Enrichment Analysis of RNA-Seq of Neuroblastoma Cells
Gepoliano Chaves
August 13th, 2025
In this code notebook my goal is to show how the enrichment plot of
signaling pathways enriched in ADRN and MES cells were generated. Here I
bring the lists of ADRN and MES genes from a different analysis. I input
the two lists of genes to the enricher function of the package
clusterProfiler. After the object is created I can look at all the
signaling pathways enriched in the ADRN and MES gene lists. I save both
ADRN and MES signalings to the same xlsx object using an xlsx
package.
1. Load libraries
library(clusterProfiler)
library(ggplot2)
2. Construct msigdb database
##_______________________________________________________##
# 2.2) Normoxia ADRN vs. MES Enrichment
library(msigdbr)
h_gene_sets_H = msigdbr(species = "Homo sapiens", category = c("H"))
h_gene_sets_C2 = msigdbr(species = "Homo sapiens", category = c("C2"))
h_gene_sets_C5 = msigdbr(species = "Homo sapiens", category = c("C5"))
# Prepare enrichment set including several gene sets
msigdbr_df <- rbind(h_gene_sets_H, h_gene_sets_C2)
msigdbr_df <- rbind(msigdbr_df, h_gene_sets_C5)
# Define database for Enrichr to look at
msigdbr_t2g = msigdbr_df %>% dplyr::distinct(gs_name, gene_symbol) %>% as.data.frame()
3. Upload list of 1298 ADRN genes
List_RNA_Normoxia_ADRN_vs_MES_Up_1298 <- readRDS("../../Hypoxia_Paper/analysis pipelines/for loop MES/data/List_RNA_Normoxia_ADRN_vs_MES_Up_1298.rds")
4. Upload list of 1469 MES genes
List_RNA_Normoxia_ADRN_vs_MES_Down_1469 <- readRDS("../../Hypoxia_Paper/analysis pipelines/for loop MES/data/List_RNA_Normoxia_ADRN_vs_MES_Down_1469.rds")
5. Construct enricher objects
# Up-regulated Enrichments (ADRN)
enrichr_RNA_Normoxia_ADRN_vs_MES_Up <- enricher(List_RNA_Normoxia_ADRN_vs_MES_Up_1298,
TERM2GENE = msigdbr_t2g)
# Down-regulated Enrichments (MES)
enrichr_RNA_Normoxia_ADRN_vs_MES_Down <- enricher(List_RNA_Normoxia_ADRN_vs_MES_Down_1469,
TERM2GENE = msigdbr_t2g)
5.1. Visualize enricher object as dataframe
5.1.1. ADRN Normoxia
Since the output of the enricher function above can be viewed as a dataframe, I want to view that output using the kable function, from kableExtra:
library(knitr)
library(kableExtra)
kable(as.data.frame(enrichr_RNA_Normoxia_ADRN_vs_MES_Up), caption="Enricher output ADRN Normoxia") %>%
kable_styling("striped", full_width = F, font_size = 12) %>%
scroll_box(width = "100%", height = "400px")| ID | Description | GeneRatio | BgRatio | RichFactor | FoldEnrichment | zScore | pvalue | p.adjust | qvalue | geneID | Count | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GOCC_SYNAPTIC_MEMBRANE | GOCC_SYNAPTIC_MEMBRANE | GOCC_SYNAPTIC_MEMBRANE | 110/1243 | 372/23056 | 0.2956989 | 5.484822 | 20.816962 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/IGSF21/OPRD1/GRIK3/RIMS3/PLPPR4/NTNG1/KCNA3/CHRNB2/SYT11/KCNJ9/ADORA1/CNTN2/KCNH1/CHRM3/OTOF/SLC8A1/NRXN1/CHRNA1/CHRND/CNTN6/LHFPL4/ATP2B2/SLC6A11/SLC6A1/GRIP2/GRM2/ERC2/CLSTN2/SLITRK3/NSG1/CHRNA9/KCTD8/GABRG1/ANK2/GLRA3/KCTD16/GABRG2/GABRP/LRFN2/RIMS1/SNAP91/CNR1/GABRR2/GRIK2/OPRM1/GRID2IP/DGKB/CHRNA2/STXBP1/GRIN1/SORCS3/ADRA2A/KCNC1/SLC6A5/SLC1A2/LRRC4C/P2RX3/SYT7/CHRM1/CNIH2/SHANK2/PDE2A/GRM5/GRIA4/DRD2/HTR3A/NECTIN1/GRIK4/IQSEC3/ENO2/PTPRO/CNTN1/FAIM2/SLC4A8/KCNC2/RPH3A/PCDH8/PCDH17/KCTD12/SLITRK1/GABRB3/GABRA5/GABRG3/CHRNA7/CPLX3/CHRNA3/CHRNB4/GSG1L/STX1B/CBLN1/SLC6A2/CACNG5/CACNG4/DCC/UNC13A/KCNC3/SHANK1/PRKCG/CACNG7/SHISA7/SNAP25/SYNDIG1/RIMS4/CACNG2/SYP/NLGN3/GRIA3/ATP2B3/NLGN4Y | 110 |
| GOCC_PRESYNAPSE | GOCC_PRESYNAPSE | GOCC_PRESYNAPSE | 119/1243 | 492/23056 | 0.2418699 | 4.486366 | 18.659839 | 0.0000000 | 0.0000000 | 0.0000000 | IGSF21/OPRD1/GRIK3/RIMS3/DNAJC6/PDE4B/NTNG1/SLC6A17/KCNA3/NGF/CHRNB2/HCN3/SYT11/KCNJ9/PPFIA4/ADORA1/KCNH1/OTOF/SLC30A3/SLC8A1/NRXN1/TMEM163/PTPRN/CNTN6/ATP2B2/SLC6A11/SLC6A1/SYN2/BSN/GRM2/ERC2/CADPS/CPLX1/KCTD8/RAB3C/KCTD16/CPLX2/SNCB/SCGN/GRM4/PACSIN1/RIMS1/SNAP91/CNR1/GRIK2/OPRM1/ICA1/NPY/DDC/PTPRN2/SLC18A1/CALB1/KCNK9/NTRK2/STXBP1/GRIN1/ADRA2A/SYT8/TH/PPFIBP2/KCNC1/SLC6A5/SLC1A2/P2RX3/SYT7/CHRM1/NRXN2/SHANK2/PDE2A/DRD2/NECTIN1/GRIK4/CNTN1/SLC4A8/KCNC2/SLC17A8/SVOP/RPH3A/P2RX7/PCDH8/PCDH17/KCTD12/SLC8A3/GABRA5/CPLX3/SCAMP5/MCTP2/STX1B/SLC6A2/DOC2B/VAMP2/RNF112/CDK5R1/SRCIN1/C1QL1/SYT4/ATCAY/UNC13A/RAB3A/SLC8A2/PPFIA3/KCNC3/PRKCG/SYT5/BRSK1/LAMP5/SNAP25/SYNDIG1/SLC32A1/RIMS4/HRH3/SEPTIN5/SEPTIN3/SYN1/SYP/NLGN3/SEPTIN6/ATP2B3/NLGN4Y | 119 |
| MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | 107/1243 | 437/23056 | 0.2448513 | 4.541666 | 17.843171 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/CHD5/DISP3/IGSF21/HTR6/EPHA8/HCRTR1/FNDC5/PLPPR5/SLC6A17/CHRNB2/FAM163A/CNTN2/KCNH1/DYSF/FBXO41/DPP10/EVX2/HOXD8/FEV/ASIC4/ECEL1/ATP2B2/SLC6A1/SCN5A/MYRIP/BSN/SLC38A3/CACNA2D2/CACNA1D/CLSTN2/SLITRK3/FGF12/FSTL4/GFRA3/PSD2/AFAP1L1/FBLL1/RASGEF1C/PACSIN1/TMEM151B/SLC35D3/MMD2/GRID2IP/JAZF1/RELN/WDR86/DLGAP2/ANK1/KCNQ3/SCRT1/TMEM215/VSTM4/DRGX/CHAT/PHYHIPL/NRG3/SLIT1/PRLHR/BRSK2/LMO1/PTPN5/SLC6A5/NELL1/C1QTNF4/NRXN2/GAL/SCN4B/HOXC10/WSCD2/ATP8A2/KL/DIO3/GABRA5/CHRNA3/HS3ST2/CBLN1/SLC6A2/JPH3/DOC2B/RAB11FIP4/TMEM132E/C1QL1/ACE/KCNH6/CACNG4/CELF4/DLL3/TTC9B/SLC8A2/KCNC3/SHISA7/RSPO4/LAMP5/VSTM2L/SLC32A1/MAFB/PTPRT/KCNK15/RIMS4/CDH22/B3GALT5/SEZ6L/NEFH/BEX1/ATP2B3/L1CAM | 107 |
| REACTOME_NEURONAL_SYSTEM | REACTOME_NEURONAL_SYSTEM | REACTOME_NEURONAL_SYSTEM | 100/1243 | 411/23056 | 0.2433090 | 4.513059 | 17.154601 | 0.0000000 | 0.0000000 | 0.0000000 | DLGAP3/GRIK3/LRRC7/KCNA3/CHRNB2/HCN3/KCNJ9/PPFIA4/KCNH1/GNG4/KCNK3/NRXN1/TUBA3E/KCNH7/CHRNA1/CHRND/SLC6A11/SLC6A1/SYN2/GRIP2/KCNH8/CACNA2D2/ADCY5/SLITRK3/BCHE/CPLX1/CHRNA9/GLRA3/GABRG2/TUBB2A/TUBB2B/LRFN2/RIMS1/GABRR2/GRIK2/DLGAP2/CHRNA2/KCNB2/KCNQ3/KCNK9/STXBP1/GRIN1/CACNA1B/CHAT/PPFIBP2/KCNJ11/KCNC1/SLC1A2/SYT7/NRXN2/KCNK7/SHANK2/GRM5/GRIA4/HTR3A/GRIK4/KCNJ8/TUBA1A/KCNC2/TUBA3C/SLITRK1/SLITRK5/KCNH5/NRXN3/KCNK10/CALM1/BEGAIN/GABRB3/GABRA5/GABRG3/CHRNA7/GJD2/CHRNA3/CHRNB4/ABAT/VAMP2/KCNH4/MAPT/PPM1E/KCNH6/CACNG4/TUBB4A/SLC1A6/KCNN1/RAB3A/GNG8/PPFIA3/KCNC3/SHANK1/PRKCG/SNAP25/SLC32A1/KCNJ6/CACNG2/TSPAN7/SYN1/NLGN3/RPS6KA6/GRIA3/NLGN4Y | 100 |
| GOCC_POSTSYNAPTIC_MEMBRANE | GOCC_POSTSYNAPTIC_MEMBRANE | GOCC_POSTSYNAPTIC_MEMBRANE | 81/1243 | 271/23056 | 0.2988930 | 5.544068 | 17.962443 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/IGSF21/OPRD1/GRIK3/PLPPR4/KCNA3/CHRNB2/ADORA1/CNTN2/KCNH1/CHRM3/SLC8A1/CHRNA1/CHRND/LHFPL4/ATP2B2/SLC6A11/SLC6A1/GRIP2/GRM2/CLSTN2/SLITRK3/NSG1/CHRNA9/KCTD8/GABRG1/ANK2/GLRA3/KCTD16/GABRG2/GABRP/LRFN2/GABRR2/GRIK2/OPRM1/GRID2IP/DGKB/CHRNA2/GRIN1/SORCS3/ADRA2A/KCNC1/LRRC4C/CHRM1/CNIH2/SHANK2/GRM5/GRIA4/DRD2/HTR3A/GRIK4/IQSEC3/PTPRO/CNTN1/FAIM2/KCNC2/RPH3A/PCDH8/PCDH17/KCTD12/SLITRK1/GABRB3/GABRA5/GABRG3/CHRNA7/CHRNA3/CHRNB4/GSG1L/CBLN1/CACNG5/CACNG4/DCC/KCNC3/SHANK1/CACNG7/SHISA7/SYNDIG1/CACNG2/NLGN3/GRIA3/NLGN4Y | 81 |
| GOBP_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | GOBP_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | GOBP_REGULATION_OF_TRANS_SYNAPTIC_SIGNALING | 101/1243 | 429/23056 | 0.2354312 | 4.366937 | 16.803918 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/DLGAP3/GRIK3/RIMS3/ELAVL4/PLPPR4/NTNG1/NGF/CHRNB2/SYT11/NTRK1/TNR/ADORA1/CNTN2/NRXN1/CNTN4/SLC6A1/PLCL2/GRM2/ERC2/IGSF11/TMEM108/CLSTN2/BCHE/CPLX1/NSG1/KIT/CPLX2/GRM6/TUBB2B/SCGN/GRM4/LRFN2/RIMS1/CNR1/GRIK2/FYN/GRID2IP/RELN/GRM8/DLGAP2/LZTS1/CALB1/SLC24A2/NTRK2/ROR2/STXBP1/GRIN1/CACNA1B/NRG3/NEURL1/SORCS3/ADRA2A/LRRC4C/P2RX3/SYT7/CNIH2/SHANK2/GRM5/DRD2/GRIK4/SLC4A8/CUX2/PCDH17/JPH4/SLC8A3/BEGAIN/CHRNA7/CPLX3/CHRNA3/CHRNB4/MCTP2/STX1B/CBLN1/JPH3/VAMP2/MAPT/CACNG5/CACNG4/CELF4/SYT4/DCC/UNC13A/RAB3A/SLC8A2/PPFIA3/SHANK1/PRKCG/CACNG7/BRSK1/SHISA7/SNAP25/RIMS4/S100B/SEPTIN5/CACNG2/MAPK8IP2/SYN1/SYP/NLGN3/NLGN4Y | 101 |
| MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | 90/1243 | 350/23056 | 0.2571429 | 4.769659 | 16.963918 | 0.0000000 | 0.0000000 | 0.0000000 | IGSF21/OPRD1/HCRTR1/GRIK3/PTGER3/SLC6A17/KCNA3/CADM3/CNTN2/SYT14/KCNH1/PGBD5/GNG4/RYR2/PLD5/KCNK3/SLC30A3/ALK/GALNT14/DPP10/AMER3/TMEM163/GALNT13/HOXD1/CDK5R2/FEV/CRYBA2/SGPP2/ECEL1/ATP2B2/KCNH8/SCN5A/MYRIP/CACNA2D2/CADPS/GPR27/PROK2/STXBP5L/GATA2/CLSTN2/PAQR9/CPLX1/PPP2R2C/KCTD8/POU4F2/ISL1/FBLL1/RASGEF1C/ACTL6B/PTPRN2/DLGAP2/RALYL/SCRT1/IGFBPL1/FAM163B/CHAT/SORCS3/DSCAML1/SCN4B/IQSEC3/RERG/WSCD2/HRK/INSM2/SYNE3/GABRA5/GABRG3/GJD2/SPINT1/CRABP1/DOK4/JPH3/RAB11FIP4/TMEM132E/SRCIN1/C1QL1/LAMA1/PLPPR3/ELAVL3/MAST1/ZNF536/PROKR2/XKR7/PTPRT/SALL4/CBLN4/HRH3/ABCG1/NEFH/ATP2B3 | 90 |
| GOBP_REGULATION_OF_MEMBRANE_POTENTIAL | GOBP_REGULATION_OF_MEMBRANE_POTENTIAL | GOBP_REGULATION_OF_MEMBRANE_POTENTIAL | 97/1243 | 425/23056 | 0.2282353 | 4.233462 | 16.060932 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/PRKCZ/NPPA/OPRD1/GRIK3/RIMS3/CLDN19/GPR88/CHRNB2/HCN3/ATP1B1/ADORA1/KCNH1/RYR2/KCNK3/SLC8A1/NRXN1/KCNH7/SCN3A/SCN1A/SCN7A/CHRNA1/CHRND/KCNH8/SCN5A/CACNA1D/IGSF11/TMEM108/FGF12/CHRNA9/GABRG1/ANK2/GLRA3/GABRG2/GABRP/RIMS1/CNR1/GABRR2/GRIK2/OPRM1/RELN/CLCN1/CHRNA2/RNF122/KCNQ3/KCNK9/NTRK2/GRIN1/KCNJ11/KCNC1/P2RX3/CHRM1/KCNK7/CNIH2/GRM5/DRD2/HTR3A/SCN4B/GRIK4/SCN3B/KCNJ8/SLC4A8/KCNC2/CUX2/P2RX7/AKAP6/KCNH5/SLC8A3/KCNK10/CALM1/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/GJD2/CHRNA3/CHRNB4/ABAT/STX1B/CBLN1/CNGB1/KCNH4/MAPT/KCNH6/DSC2/CELF4/BCL2/ATP1A3/SLC8A2/SHANK1/KCNK15/RIMS4/CACNG2/MAPK8IP2/NLGN3/GRIA3 | 97 |
| MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | 85/1243 | 345/23056 | 0.2463768 | 4.569963 | 15.948342 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/IGSF21/PAX7/EPHA8/OPRD1/HCRTR1/GRIK3/HPCAL4/SLC6A17/CADM3/CNTN2/KCNH1/PGBD5/RYR2/KCNK3/SLC30A3/ALK/BCL11A/DPP10/TMEM163/GALNT13/EVX2/WNT10A/FEV/CRYBA2/PTPRN/SGPP2/ECEL1/ATP2B2/SCN5A/CACNA2D2/GPR27/PROK2/CLSTN2/CPLX1/PPP2R2C/KCTD8/POU4F2/ISL1/FSTL4/FBLL1/RASGEF1C/TFAP2D/TFAP2B/DLGAP2/RALYL/SCRT1/IGFBPL1/FAM163B/GRIN1/CHAT/SORCS3/SLC6A5/NELL1/C1QTNF4/DRD2/DSCAML1/SCN4B/IQSEC3/HOXC10/FOXN4/FGF14/SYNE3/DEGS2/GABRA5/GABRG3/GJD2/SPINT1/JPH3/RAB11FIP4/TMEM132E/SRCIN1/C1QL1/CA10/ST8SIA3/MAST1/ZNF536/PROKR2/PTPRT/SALL4/CBLN4/HRH3/ABCG1/NEFH/MPPED1 | 85 |
| GOCC_INTRINSIC_COMPONENT_OF_SYNAPTIC_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_SYNAPTIC_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_SYNAPTIC_MEMBRANE | 56/1243 | 159/23056 | 0.3522013 | 6.532866 | 16.711669 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/OPRD1/PLPPR4/NTNG1/KCNA3/CHRNB2/KCNJ9/ADORA1/CNTN2/SLC8A1/CHRNA1/CHRND/CNTN6/ATP2B2/SLC6A11/SLC6A1/GRM2/CLSTN2/SLITRK3/CHRNA9/GABRG2/LRFN2/CNR1/OPRM1/SORCS3/ADRA2A/KCNC1/SLC6A5/SLC1A2/LRRC4C/P2RX3/SYT7/CHRM1/CNIH2/GRM5/DRD2/NECTIN1/GRIK4/PTPRO/CNTN1/PCDH8/PCDH17/SLITRK1/GABRA5/GABRG3/CPLX3/GSG1L/CACNG5/CACNG4/DCC/CACNG7/SHISA7/CACNG2/NLGN3/ATP2B3/NLGN4Y | 56 |
| GOCC_PRESYNAPTIC_MEMBRANE | GOCC_PRESYNAPTIC_MEMBRANE | GOCC_PRESYNAPTIC_MEMBRANE | 53/1243 | 142/23056 | 0.3732394 | 6.923096 | 16.900631 | 0.0000000 | 0.0000000 | 0.0000000 | IGSF21/OPRD1/GRIK3/RIMS3/NTNG1/KCNA3/CHRNB2/SYT11/KCNJ9/ADORA1/KCNH1/OTOF/NRXN1/CNTN6/ATP2B2/SLC6A11/SLC6A1/GRM2/ERC2/KCTD8/KCTD16/RIMS1/SNAP91/CNR1/GRIK2/OPRM1/STXBP1/ADRA2A/KCNC1/SLC6A5/SLC1A2/P2RX3/SYT7/CHRM1/PDE2A/DRD2/NECTIN1/GRIK4/CNTN1/SLC4A8/KCNC2/PCDH8/PCDH17/KCTD12/GABRA5/CPLX3/STX1B/SLC6A2/UNC13A/KCNC3/SNAP25/SYP/ATP2B3 | 53 |
| GOCC_NEURON_TO_NEURON_SYNAPSE | GOCC_NEURON_TO_NEURON_SYNAPSE | GOCC_NEURON_TO_NEURON_SYNAPSE | 78/1243 | 346/23056 | 0.2254335 | 4.181493 | 14.233799 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/OPRD1/DLGAP3/DNAJC6/PDE4B/LRRC7/PLPPR4/SYT11/ADORA1/KCNH1/SLC30A3/SLC8A1/BCL11A/ADD2/RAPGEF4/ATP2B2/SYN2/GRIP2/BSN/GAP43/IGSF11/TMEM108/CLSTN2/CTNND2/LRFN2/GRIK2/FYN/DLGAP2/LZTS1/DMTN/CALB1/NTRK2/GRIN1/PSD/NEURL1/SORCS3/ADRA2A/LRRC4C/P2RX3/SYT7/CHRM1/CNIH2/SHANK2/GRM5/DRD2/NECTIN1/GRIK4/IQSEC3/PTPRO/SLC4A8/NOS1/CABP1/SLITRK1/SLC8A3/CHRNA3/GSG1L/RNF112/CDK5R1/SRCIN1/CACNG5/CACNG4/DCC/ATP1A3/SLC8A2/SHANK1/PRKCG/CACNG7/SHISA7/SYNDIG1/NEFH/CACNG2/MAPK8IP2/RS1/SYN1/NLGN3/ZDHHC15/PAK3/NLGN4Y | 78 |
| GOBP_REGULATION_OF_NEUROTRANSMITTER_LEVELS | GOBP_REGULATION_OF_NEUROTRANSMITTER_LEVELS | GOBP_REGULATION_OF_NEUROTRANSMITTER_LEVELS | 60/1243 | 214/23056 | 0.2803738 | 5.200562 | 14.736953 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SYT11/OTOF/NRXN1/SLC6A11/SLC6A1/SYN2/ERC2/CADPS/BCHE/CPLX1/CPLX2/GRM4/RIMS1/CNR1/PTPRN2/SLC18A1/STXBP1/DBH/CHAT/ADRA2A/SYT8/TH/SLC6A5/SLC1A2/SYT7/NRXN2/DRD2/SLC4A8/PAH/RPH3A/NOS1/P2RX7/PRIMA1/CPLX3/CHRNA3/CHRNB4/MCTP2/ABAT/STX1B/SLC6A2/DOC2B/VAMP2/SYT4/SLC1A6/UNC13A/RAB3A/PPFIA3/PRKCG/SYT5/BRSK1/SNAP25/SLC32A1/RIMS4/HRH3/SEPTIN5/GPM6B/MAOB/SYN1/SYP | 60 |
| GOBP_NEUROTRANSMITTER_TRANSPORT | GOBP_NEUROTRANSMITTER_TRANSPORT | GOBP_NEUROTRANSMITTER_TRANSPORT | 59/1243 | 208/23056 | 0.2836538 | 5.261402 | 14.737389 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SLC6A17/SYT11/OTOF/NRXN1/SLC6A11/SLC6A1/SYN2/ERC2/CADPS/CPLX1/CPLX2/GRM4/RIMS1/CNR1/ICA1/DDC/PTPRN2/SLC18A1/STXBP1/CHAT/ADRA2A/SYT8/TH/SLC6A5/SLC1A2/SYT7/NRXN2/DRD2/SLC4A8/SLC6A15/SLC17A8/RPH3A/NOS1/P2RX7/CPLX3/CHRNA3/CHRNB4/MCTP2/STX1B/SLC6A2/DOC2B/VAMP2/SYT4/SLC1A6/UNC13A/RAB3A/PPFIA3/PRKCG/SYT5/BRSK1/SNAP25/SLC32A1/RIMS4/HRH3/SEPTIN5/GPM6B/SYN1/SYP | 59 |
| GOMF_GATED_CHANNEL_ACTIVITY | GOMF_GATED_CHANNEL_ACTIVITY | GOMF_GATED_CHANNEL_ACTIVITY | 76/1243 | 342/23056 | 0.2222222 | 4.121927 | 13.885114 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/KCNA3/CHRNB2/HCN3/KCNJ9/KCNH1/RYR2/KCNK3/KCNH7/SCN3A/SCN1A/SCN7A/CHRNA1/ASIC4/CHRND/KCNH8/SCN5A/CACNA2D2/CACNA1D/CHRNA9/GABRG1/GLRA3/GABRG2/KCNIP1/GABRP/CNR1/GABRR2/GRIK2/OPRM1/CLCN1/CHRNA2/KCNB2/KCNQ3/KCNK9/GRIN1/CACNA1B/KCNJ11/KCNC1/ANO5/P2RX3/KCNK7/GRIA4/HTR3A/SCN4B/GRIK4/SCN3B/KCNJ8/KCNC2/P2RX7/KCNH5/TMEM63C/KCNK10/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/CNGB1/KCNH4/KCNH6/CACNG5/CACNG4/CACNG1/KCNN1/KCNC3/CACNG7/TMC2/SNAP25/KCNK15/KCNJ6/CACNG2/CACNA1F/GRIA3 | 76 |
| GOBP_SYNAPSE_ORGANIZATION | GOBP_SYNAPSE_ORGANIZATION | GOBP_SYNAPSE_ORGANIZATION | 83/1243 | 418/23056 | 0.1985646 | 3.683110 | 13.215024 | 0.0000000 | 0.0000000 | 0.0000000 | IGSF21/DLGAP3/NTNG1/CHRNB2/NTRK1/TNR/PPFIA4/NFASC/CNTN2/NRXN1/ADD2/CTNNA2/CHRNA1/KIF1A/LHFPL4/SLC6A1/BSN/CAMKV/ERC2/GAP43/TMEM108/CLSTN2/SLITRK3/ADGRL3/TLR2/CTNND2/PCDHB3/PCDHB6/PCDHB10/PCDHB11/GABRG2/SNCB/LRFN2/ADGRB3/FYN/RELN/NTRK2/C1QL3/SLIT1/INA/NEURL1/PPFIBP2/LRRC4C/NRXN2/SHANK2/GRM5/VSTM5/DRD2/IL10RA/NECTIN1/PTPRO/TUBA1A/CUX2/PCDH8/PCDH17/SLITRK1/SLITRK5/SLC8A3/GABRB3/CHRNA7/ST8SIA2/CBLN1/CDK5R1/SRCIN1/C1QL1/MAPT/UNC13A/RAB3A/SLC8A2/PPFIA3/SHANK1/SHISA7/SYNDIG1/CBLN4/NEFH/CACNG2/SYN1/NLGN3/ZDHHC15/PAK3/L1CAM/RAB39B/NLGN4Y | 83 |
| MEISSNER_NPC_HCP_WITH_H3K4ME2 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | 91/1243 | 493/23056 | 0.1845842 | 3.423792 | 12.986159 | 0.0000000 | 0.0000000 | 0.0000000 | CHD5/GPR153/HTR6/RAP1GAP/AGBL4/DNAJC6/SLC44A5/PLPPR5/PLPPR4/ANKRD35/CHRNB2/PEAR1/BCL11A/DYSF/HOXD8/LHFPL4/FBLN2/BSN/FGF12/PRKG2/MARCHF11/CPLX2/GPRIN1/SNCB/N4BP3/ELOVL2/PACSIN1/TMEM151B/RIMS1/GRIK2/MAP7/NPY/ABCB4/VIPR2/MTMR7/ZMAT4/ANK1/ELAVL2/DIRAS2/ROR2/BRINP1/OLFM1/CACNA1B/FAM241B/NRG3/PIK3AP1/GOLGA7B/NEURL1/BRSK2/CDKN1C/SYT13/MAPK8IP1/CNIH2/GRIK4/KCNJ8/SVOP/DTX1/RASAL1/SRRM4/GLT1D1/CCNA1/SMAD9/RTN1/SLC8A3/PRIMA1/GSC/DLK1/CHRFAM7A/SLC27A2/TM6SF1/IRX6/SETD6/KCNH4/ACE/AATK/CELF4/ONECUT2/CAMSAP3/SLC1A6/HAPLN4/DLL3/TTC9B/ATP1A3/SHISA7/RSPO4/CHGB/SLC32A1/BMP7/SLC37A1/TMEM121B/GRK3 | 91 |
| GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_MEMBRANE | 44/1243 | 123/23056 | 0.3577236 | 6.635298 | 14.958891 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/OPRD1/PLPPR4/KCNA3/CHRNB2/ADORA1/CNTN2/SLC8A1/CHRNA1/CHRND/ATP2B2/SLC6A11/SLC6A1/GRM2/CLSTN2/SLITRK3/CHRNA9/GABRG2/LRFN2/OPRM1/SORCS3/ADRA2A/KCNC1/LRRC4C/CHRM1/CNIH2/GRM5/DRD2/GRIK4/PTPRO/CNTN1/PCDH8/PCDH17/SLITRK1/GABRA5/GSG1L/CACNG5/CACNG4/DCC/CACNG7/SHISA7/CACNG2/NLGN3/NLGN4Y | 44 |
| GOBP_VESICLE_MEDIATED_TRANSPORT_IN_SYNAPSE | GOBP_VESICLE_MEDIATED_TRANSPORT_IN_SYNAPSE | GOBP_VESICLE_MEDIATED_TRANSPORT_IN_SYNAPSE | 53/1243 | 198/23056 | 0.2676768 | 4.965049 | 13.375882 | 0.0000000 | 0.0000000 | 0.0000000 | HPCA/RIMS3/DNAJC6/OTOF/RAPGEF4/SYN2/GRIP2/BSN/ERC2/CADPS/CPLX1/NSG1/CPLX2/SNCB/PACSIN1/RIMS1/SNAP91/CNR1/DDC/SLC18A1/STXBP1/ADRA2A/BRSK2/SYT8/TH/SYT7/DRD2/SLC4A8/SLC17A8/P2RX7/PCDH17/CPLX3/GSG1L/STX1B/DOC2B/VAMP2/CDK5R1/SYT4/UNC13A/RAB3A/PPFIA3/PRKCG/SYT5/BRSK1/SNAP25/SYNDIG1/SLC32A1/RIMS4/SEPTIN5/SYN1/SYP/NLGN3/NLGN4Y | 53 |
| GOCC_DISTAL_AXON | GOCC_DISTAL_AXON | GOCC_DISTAL_AXON | 62/1243 | 270/23056 | 0.2296296 | 4.259325 | 12.859850 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/GRIK3/ELAVL4/KCNA3/HCN3/ADORA1/SLC8A1/KIF5C/MAP2/CDK5R2/PTPRN/ERC2/GAP43/CPLX1/UNC5C/CPLX2/GPRIN1/SNCB/NRSN1/SCGN/PACSIN1/CNR1/GRIK2/NPY/SLC18A1/STMN4/CALB1/NTRK2/OLFM1/GRIN1/ADRA2A/BRSK2/TH/KCNC1/P2RX3/CHRM1/SHANK2/DRD2/NECTIN1/ENO2/PTPRO/SLC4A8/KCNC2/SLC17A8/SLC8A3/CPLX3/CDK5R1/MAPT/DCC/ATCAY/UNC13A/RAB3A/SLC8A2/PRKCG/BRSK1/LAMP5/SNAP25/SLC32A1/INPP5J/SYP/SEPTIN6/L1CAM | 62 |
| REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 62/1243 | 270/23056 | 0.2296296 | 4.259325 | 12.859850 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/LRRC7/CHRNB2/KCNJ9/PPFIA4/GNG4/TUBA3E/CHRNA1/CHRND/SLC6A11/SLC6A1/SYN2/GRIP2/CACNA2D2/ADCY5/BCHE/CPLX1/CHRNA9/GLRA3/GABRG2/TUBB2A/TUBB2B/RIMS1/GABRR2/GRIK2/CHRNA2/STXBP1/GRIN1/CACNA1B/CHAT/SLC1A2/GRIA4/HTR3A/GRIK4/TUBA1A/TUBA3C/CALM1/GABRB3/GABRA5/GABRG3/CHRNA7/CHRNA3/CHRNB4/ABAT/VAMP2/MAPT/PPM1E/CACNG4/TUBB4A/SLC1A6/RAB3A/GNG8/PPFIA3/PRKCG/SNAP25/SLC32A1/KCNJ6/CACNG2/TSPAN7/SYN1/RPS6KA6/GRIA3 | 62 |
| GOBP_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | GOBP_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | GOBP_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | 43/1243 | 131/23056 | 0.3282443 | 6.088496 | 13.942184 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/PRKCZ/GRIK3/CHRNB2/ADORA1/NRXN1/CHRNA1/CHRND/IGSF11/TMEM108/CHRNA9/GABRG1/GLRA3/GABRG2/RIMS1/GABRR2/GRIK2/OPRM1/RELN/CHRNA2/GRIN1/P2RX3/CHRM1/GRM5/DRD2/GRIK4/CUX2/P2RX7/SLC8A3/GABRA5/GABRG3/CHRNA7/CHRNA3/CHRNB4/ABAT/STX1B/CBLN1/CELF4/SLC8A2/SHANK1/MAPK8IP2/NLGN3/GRIA3 | 43 |
| GOCC_ION_CHANNEL_COMPLEX | GOCC_ION_CHANNEL_COMPLEX | GOCC_ION_CHANNEL_COMPLEX | 64/1243 | 288/23056 | 0.2222222 | 4.121927 | 12.726735 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/PDE4B/OLFM3/KCNA3/CHRNB2/KCNH1/RYR2/DPP10/SCN3A/SCN1A/SCN7A/CHRNA1/UNC80/SCN5A/CACNA2D2/CACNA1D/CHRNA9/GABRG1/GLRA3/GABRG2/KCNIP1/GABRP/GABRR2/GRIK2/CLCN1/CNTNAP2/CHRNA2/KCNB2/KCNQ3/GRIN1/CACNA1B/KCNJ11/KCNC1/CNIH2/GRIA4/HTR3A/SCN4B/GRIK4/SCN3B/KCNJ8/KCNC2/AKAP6/HSPA2/CALM1/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/KCNH4/CACNG5/CACNG4/CACNG1/KCNN1/KCNC3/CACNG7/SHISA7/KCNJ6/CACNG2/CACNA1F/GRIA3 | 64 |
| GOBP_SIGNAL_RELEASE | GOBP_SIGNAL_RELEASE | GOBP_SIGNAL_RELEASE | 81/1243 | 453/23056 | 0.1788079 | 3.316650 | 11.887401 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/CHRNB2/SYT11/ADORA1/SOX11/VSNL1/OTOF/NRXN1/RAPGEF4/KLF7/ABCA12/PTPRN/SYN2/MYRIP/GRM2/ERC2/CADPS/GPR27/ADCY5/AGTR1/CPLX1/ISL1/CPLX2/SOX4/GPLD1/GRM4/TFAP2B/RIMS1/CNR1/SLC16A10/RFX6/VIP/OPRM1/ICA1/TFR2/PTPRN2/SYK/STXBP1/ADRA2A/BRSK2/SYT8/KCNJ11/SYT13/SYT7/NRXN2/GAL/DRD2/SLC4A8/RPH3A/P2RX7/IRS2/CHGA/CPLX3/CHRNA3/CHRNB4/MCTP2/ABAT/STX1B/EXOC3L1/SMPD3/DOC2B/VAMP2/SYT4/MC4R/UNC13A/RAB3A/PPFIA3/SYT3/PRKCG/SYT5/BRSK1/SNAP25/SLC32A1/RIMS4/EDN3/HRH3/SEPTIN5/PLA2G3/MAOB/SYN1/SYP | 81 |
| VERHAAK_GLIOBLASTOMA_PRONEURAL | VERHAAK_GLIOBLASTOMA_PRONEURAL | VERHAAK_GLIOBLASTOMA_PRONEURAL | 48/1243 | 177/23056 | 0.2711864 | 5.030149 | 12.848416 | 0.0000000 | 0.0000000 | 0.0000000 | CELF3/GNG4/SOX11/NRXN1/SCN3A/HOXD3/MAP2/SATB1/SOX2/ADGRL3/CXXC4/SOX4/ADGRB3/MYB/STMN4/DUSP26/MTSS1/GADD45G/RALGPS1/SORCS3/MPPED2/NRXN2/CNTN1/ASCL1/RNFT2/P2RX7/SCG3/ABAT/CDK5R1/C1QL1/MAPT/CA10/PPM1E/NOL4/MAST1/DLL3/ATP1A3/PAK5/MYT1/YPEL1/SEZ6L/NR0B1/NLGN3/ZNF711/TMEM35A/BEX1/PAK3/DCX | 48 |
| GOMF_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 83/1243 | 485/23056 | 0.1711340 | 3.174309 | 11.552531 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/KCNA3/AQP10/CHRNB2/HCN3/KCNJ9/KCNH1/RYR2/KCNK3/KCNH7/SCN3A/SCN1A/SCN7A/CHRNA1/UNC80/ASIC4/CHRND/AQP12A/KCNH8/SCN5A/CACNA2D2/CACNA1D/CHRNA9/GABRG1/GLRA3/GABRG2/KCNIP1/GABRP/CNR1/GABRR2/GRIK2/OPRM1/CLCN1/CHRNA2/KCNB2/KCNQ3/KCNK9/SLC24A2/GRIN1/CACNA1B/KCNJ11/KCNC1/ANO5/P2RX3/KCNK7/GRIA4/HTR3A/SCN4B/GRIK4/SCN3B/KCNJ8/KCNC2/P2RX7/KCNH5/TMEM63C/KCNK10/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/GJD2/CHRNA3/CHRNB4/CNGB1/KCNH4/KCNH6/CACNG5/CACNG4/CACNG1/BCL2/KCNN1/KCNC3/CACNG7/TMC2/SNAP25/KCNK15/KCNJ6/CACNG2/PKDREJ/CACNA1F/GRIA3 | 83 |
| GOMF_CATION_CHANNEL_ACTIVITY | GOMF_CATION_CHANNEL_ACTIVITY | GOMF_CATION_CHANNEL_ACTIVITY | 67/1243 | 336/23056 | 0.1994048 | 3.698694 | 11.895412 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/KCNA3/CHRNB2/HCN3/KCNJ9/KCNH1/RYR2/KCNK3/KCNH7/SCN3A/SCN1A/SCN7A/CHRNA1/UNC80/ASIC4/CHRND/KCNH8/SCN5A/CACNA2D2/CACNA1D/CHRNA9/KCNIP1/CNR1/GRIK2/OPRM1/CHRNA2/KCNB2/KCNQ3/KCNK9/SLC24A2/GRIN1/CACNA1B/KCNJ11/KCNC1/P2RX3/KCNK7/GRIA4/HTR3A/SCN4B/GRIK4/SCN3B/KCNJ8/KCNC2/P2RX7/KCNH5/TMEM63C/KCNK10/CHRNA7/CHRNA3/CHRNB4/CNGB1/KCNH4/KCNH6/CACNG5/CACNG4/CACNG1/KCNN1/KCNC3/CACNG7/TMC2/SNAP25/KCNK15/KCNJ6/CACNG2/PKDREJ/CACNA1F/GRIA3 | 67 |
| GOBP_NEUROTRANSMITTER_SECRETION | GOBP_NEUROTRANSMITTER_SECRETION | GOBP_NEUROTRANSMITTER_SECRETION | 43/1243 | 146/23056 | 0.2945205 | 5.462965 | 12.913614 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SYT11/OTOF/NRXN1/SYN2/ERC2/CADPS/CPLX1/CPLX2/GRM4/RIMS1/CNR1/PTPRN2/STXBP1/ADRA2A/SYT8/SYT7/NRXN2/DRD2/SLC4A8/RPH3A/P2RX7/CPLX3/CHRNA3/CHRNB4/MCTP2/STX1B/DOC2B/VAMP2/SYT4/UNC13A/RAB3A/PPFIA3/PRKCG/SYT5/BRSK1/SNAP25/SLC32A1/RIMS4/HRH3/SEPTIN5/SYN1/SYP | 43 |
| GOBP_COGNITION | GOBP_COGNITION | GOBP_COGNITION | 63/1243 | 306/23056 | 0.2058824 | 3.818844 | 11.849541 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/ELAVL4/GPR88/NGF/CHRNB2/SYT11/NTRK1/TNR/ADORA1/CNTN2/NRXN1/GPR155/CHL1/SLC6A1/BCHE/ATP8A1/KIT/TLR2/GLP1R/TTBK1/ADGRB3/CNR1/FYN/VIP/RELN/CNTNAP2/CALB1/SLC24A2/NTRK2/BRINP1/DBH/GRIN1/SORCS3/TH/CHRM1/NRXN2/SHANK2/GRM5/DRD2/CUX2/JPH4/SLC8A3/NRXN3/KCNK10/GABRA5/CHRNA7/JPH3/C1QL1/MAPT/SYT4/SLC8A2/SHANK1/PRKCG/BRSK1/SHISA7/PAK5/SNAP25/HRH3/S100B/MAPK8IP2/SHROOM4/NLGN3/NLGN4Y | 63 |
| MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN | 45/1243 | 162/23056 | 0.2777778 | 5.152409 | 12.660686 | 0.0000000 | 0.0000000 | 0.0000000 | TAL1/ELAVL4/SYT11/BCL11A/MAP2/SATB1/CADPS/NSG1/PDGFRA/HAND2/JAKMIP2/LY86/CNR1/FYN/SOGA3/MYB/RAPGEF5/GDAP1/ELAVL2/IGFBPL1/ALDH1A1/BRINP1/TMEM26/INA/GFRA1/BRSK2/MPPED2/FGD4/KIF21A/ABCD2/ASCL1/DACH1/RTN1/C14orf132/SCG3/RHBDL3/CDK5R1/CACNG4/NOL4/ELAVL3/NCAN/MYT1/JAM2/GPM6B/DCX | 45 |
| GOCC_NEURON_PROJECTION_TERMINUS | GOCC_NEURON_PROJECTION_TERMINUS | GOCC_NEURON_PROJECTION_TERMINUS | 40/1243 | 129/23056 | 0.3100775 | 5.751526 | 12.918581 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/GRIK3/KCNA3/HCN3/ADORA1/SLC8A1/PTPRN/BSN/CPLX1/CPLX2/SNCB/SCGN/PACSIN1/GRIK2/NPY/SLC18A1/CALB1/NTRK2/GRIN1/ADRA2A/TH/KCNC1/SLC1A2/P2RX3/CHRM1/DRD2/SLC4A8/KCNC2/SLC17A8/GCH1/SLC8A3/CPLX3/VAMP2/UNC13A/RAB3A/SLC8A2/PRKCG/SLC32A1/SYP/SEPTIN6 | 40 |
| GOBP_AXON_DEVELOPMENT | GOBP_AXON_DEVELOPMENT | GOBP_AXON_DEVELOPMENT | 78/1243 | 479/23056 | 0.1628392 | 3.020452 | 10.667032 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA8/EPHA10/PLPPR4/NTNG1/TSPAN2/NGF/CHRNB2/NTRK1/TNR/NFASC/CNTN2/DPYSL5/NRXN1/CTNNA2/KIF5C/KLF7/MAP2/CDK5R2/CHL1/CNTN6/CNTN4/EPHA6/GAP43/SEMA5B/SLITRK3/BMPR1B/UNC5C/POU4F2/ISL1/FSTL4/GFRA3/UNC5A/TUBB2B/CNR1/POU3F2/FYN/RELN/DPYSL2/NTRK2/STXBP1/OLFM1/DRGX/SLIT1/BRSK2/LRRC4C/MAP6/DRD2/DSCAML1/NECTIN1/PTPRO/CNTN1/KIF5A/ATP8A2/SLITRK1/SLITRK5/NRXN3/ISLR2/RTN4RL1/CDK5R1/MAPT/LAMA1/RNF165/DCC/BCL2/RAB3A/NOVA2/BRSK1/VSTM2L/BMP7/EDN3/CHODL/TIAM1/S100B/NEFH/ANOS1/NLGN3/PAK3/L1CAM | 78 |
| GOCC_GLUTAMATERGIC_SYNAPSE | GOCC_GLUTAMATERGIC_SYNAPSE | GOCC_GLUTAMATERGIC_SYNAPSE | 61/1243 | 317/23056 | 0.1924290 | 3.569303 | 10.995619 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/HPCA/DLGAP3/GRIK3/ELAVL4/PLPPR4/NTNG1/SLC6A17/KCNA3/TNR/SLC30A3/ATP2B2/SYN2/GRIP2/BSN/CAMKV/ERC2/CADPS/CLSTN2/CPLX1/NSG1/ADGRL3/GUCY1A1/PSD2/GABRG2/CPLX2/CNR1/GRIK2/DLGAP2/CALB1/STXBP1/NRG3/SORCS3/ADRA2A/SLC1A2/LRRC4C/CHRM1/CNIH2/SHANK2/GRM5/DRD2/PTPRO/SLC4A8/PCDH8/PCDH17/SLITRK1/GSG1L/CBLN1/CACNG5/CACNG4/SYT4/PPFIA3/SHANK1/CACNG7/SHISA7/SNAP25/CACNG2/NLGN3/PAK3/ATP2B3/NLGN4Y | 61 |
| GOBP_LEARNING | GOBP_LEARNING | GOBP_LEARNING | 40/1243 | 145/23056 | 0.2758621 | 5.116875 | 11.871077 | 0.0000000 | 0.0000000 | 0.0000000 | ELAVL4/GPR88/CHRNB2/SYT11/TNR/CNTN2/NRXN1/SLC6A1/BCHE/ATP8A1/KIT/TLR2/ADGRB3/FYN/RELN/CNTNAP2/SLC24A2/NTRK2/DBH/GRIN1/SORCS3/TH/NRXN2/SHANK2/GRM5/DRD2/JPH4/SLC8A3/NRXN3/GABRA5/JPH3/C1QL1/SLC8A2/SHANK1/BRSK1/PAK5/SNAP25/MAPK8IP2/NLGN3/NLGN4Y | 40 |
| GOCC_TRANSPORTER_COMPLEX | GOCC_TRANSPORTER_COMPLEX | GOCC_TRANSPORTER_COMPLEX | 69/1243 | 396/23056 | 0.1742424 | 3.231966 | 10.694626 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/PDE4B/OLFM3/KCNA3/CHRNB2/ATP1B1/KCNH1/RYR2/DPP10/SCN3A/SCN1A/SCN7A/CHRNA1/UNC80/SCN5A/CACNA2D2/CACNA1D/CHRNA9/ATP8A1/GABRG1/GLRA3/GABRG2/KCNIP1/GABRP/GABRR2/GRIK2/CLCN1/CNTNAP2/CHRNA2/KCNB2/KCNQ3/GRIN1/CACNA1B/KCNJ11/KCNC1/CNIH2/GRIA4/HTR3A/SCN4B/GRIK4/SCN3B/KCNJ8/KCNC2/ATP8A2/AKAP6/HSPA2/CALM1/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/CNGB1/KCNH4/CACNG5/CACNG4/CACNG1/KCNN1/ATP1A3/KCNC3/CACNG7/SHISA7/KCNJ6/CACNG2/CACNA1F/GRIA3 | 69 |
| GOMF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOMF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOMF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | 35/1243 | 111/23056 | 0.3153153 | 5.848681 | 12.223665 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/HTR6/GRIK3/CHRNB2/ADORA1/CHRM3/CHRNA1/CHRND/CHRNA9/GABRG1/GLRA3/GABRG2/GABRP/HRH2/HTR1E/GABRR2/GRIK2/CHRNA2/GRIN1/CHRM1/GRM5/GRIA4/DRD2/HTR3A/GRIK4/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/P2RY11/HRH3/GRIA3 | 35 |
| GOMF_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 72/1243 | 429/23056 | 0.1678322 | 3.113064 | 10.546011 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/KCNA3/HCN3/KCNJ9/ATP1B1/KCNH1/RYR2/KCNK3/SLC30A3/SLC8A1/KCNH7/SCN3A/SCN1A/SCN7A/ASIC4/ATP2B2/SLC6A11/SLC6A1/KCNH8/SCN5A/CACNA2D2/CACNA1D/CHRNA9/SLC10A4/KCNIP1/CNR1/GRIK2/OPRM1/SLC18A1/KCNB2/KCNQ3/KCNK9/SLC24A2/GRIN1/CACNA1B/KCNJ11/KCNC1/SLC6A5/SLC1A2/KCNK7/SCN4B/GRIK4/SCN3B/KCNJ8/SLC4A8/KCNC2/SLC6A15/KCNH5/SLC8A3/KCNK10/CHRNA7/SLC6A2/KCNH4/KCNH6/CACNG5/CACNG4/CACNG1/SLC1A6/KCNN1/ATP4A/ATP1A3/SLC8A2/KCNC3/CACNG7/TMC2/SNAP25/KCNK15/KCNJ6/CACNG2/PKDREJ/CACNA1F/ATP2B3 | 72 |
| GOBP_REGULATION_OF_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_SYNAPTIC_PLASTICITY | 46/1243 | 197/23056 | 0.2335025 | 4.331162 | 11.208841 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/RIMS3/TNR/ADORA1/CNTN2/CNTN4/ERC2/IGSF11/NSG1/KIT/CPLX2/SCGN/RIMS1/GRIK2/GRID2IP/RELN/LZTS1/CALB1/SLC24A2/NTRK2/STXBP1/GRIN1/NEURL1/SORCS3/P2RX3/SYT7/SHANK2/GRM5/DRD2/JPH4/SLC8A3/CHRNA7/CBLN1/JPH3/VAMP2/MAPT/SYT4/RAB3A/SLC8A2/PPFIA3/PRKCG/BRSK1/SHISA7/SNAP25/S100B/SYP | 46 |
| GOCC_EXOCYTIC_VESICLE | GOCC_EXOCYTIC_VESICLE | GOCC_EXOCYTIC_VESICLE | 48/1243 | 216/23056 | 0.2222222 | 4.121927 | 11.004290 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/PDE4B/SLC6A17/NGF/SYT11/OTOF/SLC30A3/TMEM163/PTPRN/SYN2/BSN/RAB3C/SNAP91/ICA1/DDC/PTPRN2/SLC18A1/KCNK9/GRIN1/SYT8/TH/SYT13/SYT7/DRD2/SLC4A8/SLC17A8/SVOP/RPH3A/CPLX3/SCAMP5/MCTP2/STX1B/VAMP2/RNF112/SYT4/UNC13A/RAB3A/SYT3/SYT5/BRSK1/LAMP5/SNAP25/SYNDIG1/SLC32A1/SEPTIN5/SYN1/SYP/SEPTIN6 | 48 |
| GOBP_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 76/1243 | 483/23056 | 0.1573499 | 2.918632 | 10.172577 | 0.0000000 | 0.0000000 | 0.0000000 | NPPA/HPCA/PDE4B/KCNA3/KCNJ9/ATP1B1/KCNH1/RYR2/CHRM3/RGS7/SLC8A1/DPP10/KCNH7/SCN3A/SCN1A/SCN7A/KCNH8/SCN5A/CACNA2D2/CACNA1D/COX17/FGF12/ANK2/KCNIP1/FYN/OPRM1/TWIST1/RELN/CLCN1/KCNB2/KCNQ3/CACNA1B/ADRA2A/KCNJ11/KCNC1/KCNK7/CNIH2/GAL/GRM5/DRD2/SCN4B/SCN3B/KCNJ8/KCNC2/NOS1/P2RX7/FGF14/JPH4/AKAP6/KCNH5/HSPA2/KCNK10/CALM1/GSG1L/JPH3/FGF11/VAMP2/KCNH4/KCNH6/CACNG5/CACNG4/CACNG1/JSRP1/HRC/KCNC3/SHANK1/CACNG7/SHISA7/TMC2/KCNK15/EDN3/KCNJ6/CACNG2/MAPK8IP2/CACNA1F/NLGN3 | 76 |
| KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | 54/1243 | 272/23056 | 0.1985294 | 3.682457 | 10.623379 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/HTR6/OPRD1/HCRTR1/GRIK3/PTGER3/CHRNB2/ADORA1/CHRM3/CHRNA1/CHRND/GRM2/AGTR1/CHRNA9/GABRG1/NPY2R/GLRA3/GABRG2/GABRP/HRH2/GRM6/GRM4/GLP1R/HTR1E/CNR1/GABRR2/GRIK2/OPRM1/ADCYAP1R1/GRM8/VIPR2/CHRNA2/PRSS3/GRIN1/ADRA2A/PRLHR/P2RX3/CHRM1/GRM5/GRIA4/DRD2/GRIK4/P2RX7/GABRB3/GABRA5/GABRG3/CHRNA7/CHRNA3/CHRNB4/SSTR2/MC4R/P2RY11/HRH3/GRIA3 | 54 |
| GOCC_GABA_ERGIC_SYNAPSE | GOCC_GABA_ERGIC_SYNAPSE | GOCC_GABA_ERGIC_SYNAPSE | 27/1243 | 70/23056 | 0.3857143 | 7.154488 | 12.310329 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/SLC6A17/ATP2B2/SLC6A11/SLC6A1/BSN/ERC2/GAP43/SLITRK3/GUCY1A1/GABRG2/CNR1/GABRR2/CALB1/ADRA2A/DRD2/IQSEC3/PTPRO/PCDH17/SLITRK1/GABRA5/GABRG3/SLC32A1/CBLN4/NLGN3/ATP2B3/NLGN4Y | 27 |
| GOBP_CHEMICAL_SYNAPTIC_TRANSMISSION_POSTSYNAPTIC | GOBP_CHEMICAL_SYNAPTIC_TRANSMISSION_POSTSYNAPTIC | GOBP_CHEMICAL_SYNAPTIC_TRANSMISSION_POSTSYNAPTIC | 32/1243 | 101/23056 | 0.3168317 | 5.876807 | 11.725140 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/CHRNB2/ADORA1/NRXN1/CHRNA1/CHRND/IGSF11/TMEM108/CHRNA9/GLRA3/RIMS1/GRIK2/OPRM1/RELN/CHRNA2/GRIN1/P2RX3/DRD2/CUX2/P2RX7/SLC8A3/CHRNA7/CHRNA3/CHRNB4/ABAT/STX1B/CBLN1/CELF4/SLC8A2/SHANK1/MAPK8IP2/NLGN3 | 32 |
| GOCC_INTRINSIC_COMPONENT_OF_PRESYNAPTIC_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_PRESYNAPTIC_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_PRESYNAPTIC_MEMBRANE | 27/1243 | 73/23056 | 0.3698630 | 6.860468 | 11.971561 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/NTNG1/KCNA3/CHRNB2/KCNJ9/ADORA1/CNTN6/ATP2B2/SLC6A11/SLC6A1/CNR1/OPRM1/ADRA2A/KCNC1/SLC6A5/SLC1A2/P2RX3/SYT7/CHRM1/DRD2/NECTIN1/GRIK4/CNTN1/PCDH17/GABRA5/CPLX3/ATP2B3 | 27 |
| GOMF_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | 27/1243 | 73/23056 | 0.3698630 | 6.860468 | 11.971561 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/CHRNB2/CHRNA1/CHRND/CHRNA9/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/GRIK2/CHRNA2/GRIN1/P2RX3/GRIA4/HTR3A/GRIK4/P2RX7/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/GRIA3 | 27 |
| GOMF_VOLTAGE_GATED_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_CHANNEL_ACTIVITY | 45/1243 | 203/23056 | 0.2216749 | 4.111775 | 10.630287 | 0.0000000 | 0.0000000 | 0.0000000 | KCNA3/HCN3/KCNJ9/KCNH1/KCNK3/KCNH7/SCN3A/SCN1A/SCN7A/KCNH8/SCN5A/CACNA2D2/CACNA1D/KCNIP1/CNR1/OPRM1/CLCN1/KCNB2/KCNQ3/KCNK9/GRIN1/CACNA1B/KCNJ11/KCNC1/KCNK7/SCN4B/SCN3B/KCNJ8/KCNC2/KCNH5/KCNK10/KCNH4/KCNH6/CACNG5/CACNG4/CACNG1/KCNN1/KCNC3/CACNG7/TMC2/SNAP25/KCNK15/KCNJ6/CACNG2/CACNA1F | 45 |
| GOCC_CATION_CHANNEL_COMPLEX | GOCC_CATION_CHANNEL_COMPLEX | GOCC_CATION_CHANNEL_COMPLEX | 46/1243 | 215/23056 | 0.2139535 | 3.968553 | 10.439193 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/PDE4B/OLFM3/KCNA3/KCNH1/RYR2/DPP10/SCN3A/SCN1A/SCN7A/UNC80/SCN5A/CACNA2D2/CACNA1D/KCNIP1/GRIK2/CNTNAP2/KCNB2/KCNQ3/GRIN1/CACNA1B/KCNJ11/KCNC1/CNIH2/GRIA4/HTR3A/SCN4B/GRIK4/SCN3B/KCNJ8/KCNC2/AKAP6/HSPA2/CALM1/KCNH4/CACNG5/CACNG4/CACNG1/KCNN1/KCNC3/CACNG7/SHISA7/KCNJ6/CACNG2/CACNA1F/GRIA3 | 46 |
| GOBP_REGULATED_EXOCYTOSIS | GOBP_REGULATED_EXOCYTOSIS | GOBP_REGULATED_EXOCYTOSIS | 48/1243 | 235/23056 | 0.2042553 | 3.788665 | 10.257071 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SYT11/OTOF/RAPGEF4/ABCA12/CDK5R2/SYN2/ERC2/CADPS/GATA2/CPLX1/KIT/CPLX2/RIMS1/CNR1/DMTN/SYK/STXBP1/ADRA2A/SYT8/SYT13/SPI1/SYT7/DRD2/SLC4A8/P2RX7/CHGA/CPLX3/SCAMP5/STX1B/DOC2B/VAMP2/SYT4/UNC13A/RAB3A/PPFIA3/SYT3/NKG7/PRKCG/SYT5/SNAP25/RIMS4/ITGB2/SEPTIN5/PLA2G3/SYN1/SYP/IL13RA2 | 48 |
| GOMF_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_LIGAND_GATED_ION_CHANNEL_ACTIVITY | 37/1243 | 145/23056 | 0.2551724 | 4.733110 | 10.764482 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/CHRNB2/KCNJ9/RYR2/KCNH7/CHRNA1/ASIC4/CHRND/CHRNA9/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/GRIK2/CHRNA2/GRIN1/KCNJ11/P2RX3/GRIA4/HTR3A/GRIK4/KCNJ8/P2RX7/GABRB3/GABRA5/GABRG3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/CNGB1/KCNH6/KCNN1/KCNJ6/GRIA3 | 37 |
| RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 17/1243 | 28/23056 | 0.6071429 | 11.261694 | 12.969714 | 0.0000000 | 0.0000000 | 0.0000000 | RGS5/KIF5C/FEV/GAP43/GATA2/ISL1/CD24/DDC/ENPP2/TMOD1/DBH/INA/RIMBP2/DLK1/ELAVL3/CHGB/DCX | 17 |
| SABATES_COLORECTAL_ADENOMA_DN | SABATES_COLORECTAL_ADENOMA_DN | SABATES_COLORECTAL_ADENOMA_DN | 54/1243 | 299/23056 | 0.1806020 | 3.349928 | 9.763218 | 0.0000000 | 0.0000000 | 0.0000000 | ACKR1/DPT/NRXN1/MEIS1/DPP10/KIF5C/SCN7A/CHRNA1/FEV/CRYBA2/CNTN4/CPB1/BCHE/KNG1/UNC5C/ANK2/ENPP6/C7/GFRA3/SPINK5/SCGN/RFX6/PKIB/VIP/NPY/VSTM2A/RUNDC3B/SCARA5/PI15/FAM13C/ANO5/NAALADL1/RERG/KCTD12/RTN1/CHGA/PRIMA1/SYNE3/MFAP4/PPY/LAMA1/ZNF536/CHGB/EDN3/CHODL/JAM2/B3GALT5/GPM6B/TSPAN7/NEXMIF/NAP1L3/CHRDL1/XPNPEP2/L1CAM | 54 |
| GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_SPECIALIZATION_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_SPECIALIZATION_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_SPECIALIZATION_MEMBRANE | 27/1243 | 80/23056 | 0.3375000 | 6.260177 | 11.250416 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/PLPPR4/CHRNB2/CHRNA1/CHRND/ATP2B2/CLSTN2/SLITRK3/CHRNA9/GABRG2/LRFN2/SORCS3/ADRA2A/LRRC4C/CHRM1/CNIH2/PTPRO/SLITRK1/GABRA5/GSG1L/CACNG4/DCC/CACNG7/SHISA7/CACNG2/NLGN3/NLGN4Y | 27 |
| MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 44/1243 | 210/23056 | 0.2095238 | 3.886388 | 10.030435 | 0.0000000 | 0.0000000 | 0.0000000 | DISP3/PTGER3/GPR88/NTNG1/KCNA3/NMNAT2/ADORA1/GALNT14/AMER3/CXCR4/KIF5C/HOXD1/CDK5R2/SATB1/MYRIP/CELSR3/PAQR9/NEUROG2/UNC5A/SLC35D3/RELN/PTPRN2/XKR5/SLC24A2/CDHR1/INA/PTPN5/TSPAN18/FGF19/HOXC4/SLC6A15/HRK/PCDH8/GPC5/INSM2/GCH1/ST8SIA2/CBLN1/FGF11/LAMA1/CHST8/GNG8/CDH22/MAPK8IP2 | 44 |
| VECCHI_GASTRIC_CANCER_EARLY_DN | VECCHI_GASTRIC_CANCER_EARLY_DN | VECCHI_GASTRIC_CANCER_EARLY_DN | 62/1243 | 384/23056 | 0.1614583 | 2.994838 | 9.409980 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/KANK4/DNAJC6/PTGER3/DPT/RGS13/ESRRG/SUSD4/CHRM3/KIF5C/SCN7A/GPR155/GRIP2/MYRIP/GPR27/ST3GAL6/KLF15/AGTR1/BCHE/SOX2/ATP13A4/SHISA3/KIT/ADGRL3/BMPR1B/UBE2QL1/C7/C6/PLCXD3/SELENOP/FUT9/PKIB/VSTM2A/SCARA5/ENPP2/ALDH1A1/INA/RASSF10/SLC1A2/CNTN1/PELI2/CHGA/PRIMA1/C14orf132/GABRB3/ARRDC4/ABAT/HLF/SYT4/ATP4A/CHGB/TMPRSS15/JAM2/GPM6B/NEXMIF/RPS6KA6/TCEAL2/BEX5/BEX1/BEX2/CHRDL1/SEPTIN6 | 62 |
| GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOMF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | 24/1243 | 64/23056 | 0.3750000 | 6.955752 | 11.389343 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/CHRNB2/CHRM3/CHRNA1/CHRND/CHRNA9/GABRG1/GABRG2/GABRR2/GRIK2/CHRNA2/CHRM1/GRM5/DRD2/GRIK4/GABRA5/GABRG3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/HRH3/GRIA3 | 24 |
| GOCC_SYNAPTIC_VESICLE_MEMBRANE | GOCC_SYNAPTIC_VESICLE_MEMBRANE | GOCC_SYNAPTIC_VESICLE_MEMBRANE | 30/1243 | 103/23056 | 0.2912621 | 5.402526 | 10.689595 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/SLC6A17/OTOF/SLC30A3/TMEM163/SYN2/BSN/RAB3C/ICA1/PTPRN2/SLC18A1/SYT8/SYT7/DRD2/SLC17A8/SVOP/RPH3A/CPLX3/SCAMP5/MCTP2/VAMP2/SYT4/UNC13A/RAB3A/SYT5/LAMP5/SYNDIG1/SLC32A1/SYN1/SYP | 30 |
| GOMF_TRANSMITTER_GATED_CHANNEL_ACTIVITY | GOMF_TRANSMITTER_GATED_CHANNEL_ACTIVITY | GOMF_TRANSMITTER_GATED_CHANNEL_ACTIVITY | 23/1243 | 60/23056 | 0.3833333 | 7.110324 | 11.312906 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/CHRNB2/CHRNA1/CHRND/CHRNA9/GABRG1/GLRA3/GABRG2/GABRR2/GRIK2/CHRNA2/GRIN1/GRIA4/HTR3A/GRIK4/GABRB3/GABRA5/GABRG3/CHRNA7/CHRNA3/CHRNB4/GRIA3 | 23 |
| CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | 39/1243 | 176/23056 | 0.2215909 | 4.110217 | 9.887340 | 0.0000000 | 0.0000000 | 0.0000000 | AK4/PLPPR4/RGS13/PPFIA4/ESRRG/VSNL1/SIX3/BCL11A/HK2/CXCR4/RAPGEF4/ABCA12/CADPS/COX17/PDGFRA/C7/H4C3/TFAP2B/CD24/MYB/ICA1/TWIST1/ELMO1/SLC18A1/RLN2/MXI1/LMO1/NELL1/ASCL1/RPH3A/DACH1/RTN1/CHGA/CHRNA3/SLC6A2/DOK4/MFAP4/PPEF1/CHRDL1 | 39 |
| GOCC_PERIKARYON | GOCC_PERIKARYON | GOCC_PERIKARYON | 36/1243 | 153/23056 | 0.2352941 | 4.364394 | 9.967052 | 0.0000000 | 0.0000000 | 0.0000000 | NPPA/HPCA/GRIK3/ELAVL4/SYT11/RGS8/KCNH1/PTPRN/GAP43/CPLX1/GLRA3/CTNND2/CPLX2/GRIK2/VIP/OPRM1/NPY/CNTNAP2/KCNB2/OLFM1/OPN4/NEURL1/TH/DRD2/ENO2/KIF5A/KCNC2/SLC17A8/SLC8A3/NGB/RTN4RL1/RNF112/CDK5R1/SLC8A2/KCNC3/CACNA1F | 36 |
| GOBP_SYNAPTIC_VESICLE_EXOCYTOSIS | GOBP_SYNAPTIC_VESICLE_EXOCYTOSIS | GOBP_SYNAPTIC_VESICLE_EXOCYTOSIS | 30/1243 | 108/23056 | 0.2777778 | 5.152409 | 10.325237 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/OTOF/ERC2/CADPS/CPLX1/CPLX2/RIMS1/CNR1/STXBP1/ADRA2A/SYT8/SYT7/DRD2/SLC4A8/P2RX7/CPLX3/STX1B/DOC2B/VAMP2/SYT4/UNC13A/RAB3A/PPFIA3/PRKCG/SYT5/SNAP25/RIMS4/SEPTIN5/SYN1/SYP | 30 |
| REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION | REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION | REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION | 42/1243 | 205/23056 | 0.2048780 | 3.800216 | 9.613383 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/LRRC7/CHRNB2/KCNJ9/GNG4/TUBA3E/CHRNA1/CHRND/GRIP2/ADCY5/CHRNA9/GLRA3/GABRG2/TUBB2A/TUBB2B/GABRR2/GRIK2/CHRNA2/GRIN1/GRIA4/HTR3A/GRIK4/TUBA1A/TUBA3C/CALM1/GABRB3/GABRA5/GABRG3/CHRNA7/CHRNA3/CHRNB4/MAPT/PPM1E/CACNG4/TUBB4A/GNG8/PRKCG/KCNJ6/CACNG2/TSPAN7/RPS6KA6/GRIA3 | 42 |
| GOCC_POSTSYNAPTIC_SPECIALIZATION_MEMBRANE | GOCC_POSTSYNAPTIC_SPECIALIZATION_MEMBRANE | GOCC_POSTSYNAPTIC_SPECIALIZATION_MEMBRANE | 31/1243 | 116/23056 | 0.2672414 | 4.956973 | 10.198958 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/PLPPR4/CHRNB2/KCNH1/CHRNA1/CHRND/ATP2B2/CLSTN2/SLITRK3/CHRNA9/GABRG2/LRFN2/SORCS3/ADRA2A/LRRC4C/CHRM1/CNIH2/GRM5/PTPRO/SLITRK1/GABRA5/GSG1L/CACNG5/CACNG4/DCC/CACNG7/SHISA7/SYNDIG1/CACNG2/NLGN3/NLGN4Y | 31 |
| GOCC_PRESYNAPTIC_ACTIVE_ZONE | GOCC_PRESYNAPTIC_ACTIVE_ZONE | GOCC_PRESYNAPTIC_ACTIVE_ZONE | 25/1243 | 75/23056 | 0.3333333 | 6.182891 | 10.731950 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/NTNG1/SYT11/PPFIA4/ADORA1/OTOF/ATP2B2/BSN/ERC2/RIMS1/STXBP1/ADRA2A/PPFIBP2/SHANK2/NECTIN1/CPLX3/STX1B/UNC13A/RAB3A/PPFIA3/BRSK1/SLC32A1/RIMS4/SYN1/SYP | 25 |
| GOBP_NEURON_PROJECTION_GUIDANCE | GOBP_NEURON_PROJECTION_GUIDANCE | GOBP_NEURON_PROJECTION_GUIDANCE | 45/1243 | 235/23056 | 0.1914894 | 3.551874 | 9.386121 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA8/EPHA10/NTRK1/TNR/NFASC/CNTN2/DPYSL5/NRXN1/KIF5C/KLF7/CDK5R2/CHL1/CNTN6/CNTN4/EPHA6/GAP43/SEMA5B/BMPR1B/UNC5C/POU4F2/ISL1/GFRA3/UNC5A/TUBB2B/FYN/RELN/DPYSL2/DRGX/SLIT1/DSCAML1/NECTIN1/PTPRO/CNTN1/KIF5A/NRXN3/CDK5R1/LAMA1/RNF165/DCC/NOVA2/VSTM2L/BMP7/EDN3/ANOS1/L1CAM | 45 |
| GOBP_MULTICELLULAR_ORGANISMAL_SIGNALING | GOBP_MULTICELLULAR_ORGANISMAL_SIGNALING | GOBP_MULTICELLULAR_ORGANISMAL_SIGNALING | 37/1243 | 165/23056 | 0.2242424 | 4.159399 | 9.722423 | 0.0000000 | 0.0000000 | 0.0000000 | CLDN19/GPR88/ATP1B1/TNR/NFASC/RYR2/SLC8A1/SCN3A/SCN1A/SCN7A/CHRNA1/ATP2B2/SCN5A/CACNA1D/FGF12/ANK2/ISL1/GRIK2/CLCN1/CNTNAP2/NTRK2/P2RX3/SCN4B/SCN3B/SLC8A3/CALM1/CHRNB4/KCNH6/CACNG5/CACNG4/DSC2/ATP1A3/SLC8A2/HRC/CACNG7/CACNG2/ATP2B3 | 37 |
| GOBP_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | GOBP_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | GOBP_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | 24/1243 | 70/23056 | 0.3428571 | 6.359545 | 10.720268 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/PLPPR4/NTRK1/TNR/ADORA1/NRXN1/GRM2/GRM6/GRM4/CNR1/GRIK2/RELN/GRM8/ROR2/STXBP1/GRM5/DRD2/CACNG5/CACNG4/UNC13A/CACNG7/CACNG2/MAPK8IP2/NLGN3 | 24 |
| GOMF_VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_CATION_CHANNEL_ACTIVITY | 34/1243 | 144/23056 | 0.2361111 | 4.379548 | 9.711107 | 0.0000000 | 0.0000000 | 0.0000000 | KCNA3/HCN3/KCNJ9/KCNH1/KCNK3/KCNH7/KCNH8/CACNA2D2/CACNA1D/CNR1/OPRM1/KCNB2/KCNQ3/KCNK9/GRIN1/CACNA1B/KCNJ11/KCNC1/KCNJ8/KCNC2/KCNH5/KCNH4/KCNH6/CACNG5/CACNG4/CACNG1/KCNN1/KCNC3/CACNG7/TMC2/SNAP25/KCNJ6/CACNG2/CACNA1F | 34 |
| GOBP_EXOCYTOSIS | GOBP_EXOCYTOSIS | GOBP_EXOCYTOSIS | 57/1243 | 360/23056 | 0.1583333 | 2.936873 | 8.841749 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SYT11/VSNL1/OTOF/RAPGEF4/ABCA12/CDK5R2/SYN2/ERC2/CADPS/STXBP5L/GATA2/CPLX1/KIT/RAB3C/CPLX2/RIMS1/CNR1/DMTN/ANK1/SYK/STXBP1/ADRA2A/BRSK2/SYT8/SYT13/SPI1/SYT7/DRD2/SLC4A8/P2RX7/STXBP6/CHGA/CPLX3/SCAMP5/STX1B/EXOC3L1/SMPD3/DOC2B/VAMP2/SRCIN1/SYT4/UNC13A/RAB3A/PPFIA3/SYT3/NKG7/PRKCG/SYT5/SNAP25/RIMS4/ITGB2/SEPTIN5/PLA2G3/SYN1/SYP/IL13RA2 | 57 |
| GOCC_TRANSPORT_VESICLE | GOCC_TRANSPORT_VESICLE | GOCC_TRANSPORT_VESICLE | 61/1243 | 403/23056 | 0.1513648 | 2.807615 | 8.738887 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/PDE4B/SLC6A17/NGF/SYT11/OTOF/SLC30A3/TMEM163/ABCA12/PTPRN/SYN2/MYRIP/BSN/CPA3/ECE2/RAB3C/NRSN1/SCGN/SNAP91/ARFGEF3/ICA1/DDC/PTPRN2/SLC18A1/KCNK9/DBH/GRIN1/SYT8/TH/SYT13/SYT7/CNIH2/MAP6/DRD2/SLC4A8/SLC17A8/SVOP/RPH3A/CHGA/SCG3/CPLX3/SCAMP5/MCTP2/STX1B/EXOC3L1/VAMP2/RNF112/SYT4/UNC13A/RAB3A/SYT3/SYT5/BRSK1/LAMP5/SNAP25/SYNDIG1/SLC32A1/SEPTIN5/SYN1/SYP/SEPTIN6 | 61 |
| GOBP_REGULATION_OF_NERVOUS_SYSTEM_PROCESS | GOBP_REGULATION_OF_NERVOUS_SYSTEM_PROCESS | GOBP_REGULATION_OF_NERVOUS_SYSTEM_PROCESS | 33/1243 | 138/23056 | 0.2391304 | 4.435552 | 9.662915 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/OPRD1/DLGAP3/TNR/ADORA1/NRXN1/IGSF11/TMEM108/FGF12/RIMS1/VIP/OPRM1/RELN/DLGAP2/GRIN1/P2RX3/CNIH2/CUX2/SLC8A3/BEGAIN/CHRNA7/CHRNB4/ABAT/STX1B/CBLN1/CACNG5/CACNG4/CELF4/SLC8A2/SHANK1/SHISA7/JAM2/NLGN3 | 33 |
| GOBP_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | GOBP_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | GOBP_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | 27/1243 | 94/23056 | 0.2872340 | 5.327810 | 10.036625 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/PLPPR4/NTRK1/TNR/ADORA1/NRXN1/GRM2/GRM6/GRM4/CNR1/GRIK2/RELN/GRM8/ROR2/STXBP1/CNIH2/GRM5/DRD2/GRIK4/SLC17A8/CACNG5/CACNG4/UNC13A/CACNG7/CACNG2/MAPK8IP2/NLGN3 | 27 |
| GOBP_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | GOBP_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | GOBP_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | 35/1243 | 161/23056 | 0.2173913 | 4.032320 | 9.216756 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/RIMS3/NTRK1/TNR/ADORA1/NRXN1/IGSF11/CLSTN2/NSG1/SCGN/RIMS1/CNR1/GRIK2/RELN/CALB1/SLC24A2/NTRK2/ROR2/STXBP1/SHANK2/DRD2/SLC4A8/SLC8A3/CHRNA7/STX1B/VAMP2/CACNG5/CACNG4/SLC8A2/PRKCG/CACNG7/SHISA7/SNAP25/CACNG2/NLGN3 | 35 |
| GOCC_TRANSPORT_VESICLE_MEMBRANE | GOCC_TRANSPORT_VESICLE_MEMBRANE | GOCC_TRANSPORT_VESICLE_MEMBRANE | 40/1243 | 205/23056 | 0.1951220 | 3.619253 | 8.992123 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/SLC6A17/OTOF/SLC30A3/TMEM163/ABCA12/PTPRN/SYN2/BSN/ECE2/RAB3C/SCGN/ARFGEF3/ICA1/PTPRN2/SLC18A1/DBH/SYT8/SYT7/CNIH2/MAP6/DRD2/SLC17A8/SVOP/RPH3A/SCG3/CPLX3/SCAMP5/MCTP2/VAMP2/SYT4/UNC13A/RAB3A/SYT3/SYT5/LAMP5/SYNDIG1/SLC32A1/SYN1/SYP | 40 |
| GOCC_TERMINAL_BOUTON | GOCC_TERMINAL_BOUTON | GOCC_TERMINAL_BOUTON | 19/1243 | 48/23056 | 0.3958333 | 7.342183 | 10.499784 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/ADORA1/CPLX1/CPLX2/SCGN/GRIK2/NPY/SLC18A1/CALB1/NTRK2/GRIN1/TH/P2RX3/SLC4A8/KCNC2/CPLX3/UNC13A/RAB3A/SYP | 19 |
| GOBP_AMINE_TRANSPORT | GOBP_AMINE_TRANSPORT | GOBP_AMINE_TRANSPORT | 27/1243 | 100/23056 | 0.2700000 | 5.008142 | 9.588604 | 0.0000000 | 0.0000000 | 0.0000000 | CHRNB2/SYT11/ADORA1/SLC6A1/SLC38A3/GRM2/CNR1/VIP/DDC/SLC18A1/STXBP1/ADRA2A/SYT8/TH/SYT13/SYT7/DRD2/P2RX7/CHGA/CHRNA3/RHCG/ABAT/SYT4/RAB3A/SYT3/SYT5/HRH3 | 27 |
| LEE_TARGETS_OF_PTCH1_AND_SUFU_DN | LEE_TARGETS_OF_PTCH1_AND_SUFU_DN | LEE_TARGETS_OF_PTCH1_AND_SUFU_DN | 25/1243 | 87/23056 | 0.2873563 | 5.330078 | 9.659280 | 0.0000000 | 0.0000000 | 0.0000000 | TSPAN2/ATP1B1/VSNL1/SLC8A1/KIF1A/ATP2B2/CLSTN2/GUCY1A1/NRSN1/CA8/CALB1/FAM241B/C1QTNF4/CNIH2/KIF5A/NRXN3/CKMT1A/CBLN1/VAMP2/SLC1A6/RAB3A/PRKCG/SLC32A1/NEFH/PCSK1N | 25 |
| GOMF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY_INVOLVED_IN_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | GOMF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY_INVOLVED_IN_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | GOMF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY_INVOLVED_IN_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | 19/1243 | 49/23056 | 0.3877551 | 7.192342 | 10.358180 | 0.0000000 | 0.0000000 | 0.0000000 | GABRD/GRIK3/CHRNB2/CHRNA1/CHRND/CHRNA9/GABRG1/GABRG2/GABRR2/GRIK2/CHRNA2/CHRM1/GRIK4/GABRA5/GABRG3/CHRNA7/CHRNA3/CHRNB4/GRIA3 | 19 |
| MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 32/1243 | 143/23056 | 0.2237762 | 4.150752 | 9.021976 | 0.0000000 | 0.0000000 | 0.0000000 | DISP3/EPHA10/KANK4/GPR88/NTNG1/NMNAT2/ADORA1/KIF5C/SATB1/CELSR3/NEUROG2/UNC5A/KHDRBS2/SLC35D3/RELN/GRM8/SLC24A2/INA/ADRA2A/PTPN5/TSPAN18/FGF19/HOXC4/PCDH8/GPC5/GCH1/ST8SIA2/CBLN1/FGF11/CHST8/CDH22/MAPK8IP2 | 32 |
| REACTOME_CARDIAC_CONDUCTION | REACTOME_CARDIAC_CONDUCTION | REACTOME_CARDIAC_CONDUCTION | 30/1243 | 127/23056 | 0.2362205 | 4.381576 | 9.121976 | 0.0000000 | 0.0000000 | 0.0000000 | NPPA/ATP1B1/RYR2/KCNK3/SLC8A1/SCN3A/SCN1A/SCN7A/ATP2B2/SCN5A/CACNA2D2/FGF12/KCNIP1/KCNK9/KCNJ11/KCNK7/SCN4B/SCN3B/NOS1/FGF14/SLC8A3/KCNK10/CALM1/FGF11/CACNG4/ATP1A3/SLC8A2/CACNG7/KCNK15/ATP2B3 | 30 |
| GOBP_POTASSIUM_ION_TRANSPORT | GOBP_POTASSIUM_ION_TRANSPORT | GOBP_POTASSIUM_ION_TRANSPORT | 43/1243 | 243/23056 | 0.1769547 | 3.282275 | 8.537691 | 0.0000000 | 0.0000000 | 0.0000000 | NPPA/KCNA3/HCN3/KCNJ9/ATP1B1/ADORA1/KCNH1/RGS7/KCNK3/DPP10/KCNH7/KCNH8/CACNA1D/ANK2/KCNIP1/VIP/KCNB2/KCNQ3/KCNK9/SLC24A2/ADRA2A/KCNJ11/KCNC1/KCNK7/GAL/DRD2/KCNJ8/KCNC2/NOS1/AKAP6/KCNH5/KCNK10/VAMP2/KCNH4/KCNH6/KCNN1/ATP4A/ATP1A3/KCNC3/SNAP25/KCNK15/EDN3/KCNJ6 | 43 |
| GOBP_REGULATION_OF_EXOCYTOSIS | GOBP_REGULATION_OF_EXOCYTOSIS | GOBP_REGULATION_OF_EXOCYTOSIS | 39/1243 | 206/23056 | 0.1893204 | 3.511642 | 8.643878 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SYT11/VSNL1/RAPGEF4/CDK5R2/CADPS/STXBP5L/GATA2/CPLX1/RAB3C/CPLX2/CNR1/SYK/STXBP1/ADRA2A/SYT8/SYT13/SPI1/SYT7/DRD2/SLC4A8/STXBP6/SCAMP5/STX1B/SMPD3/DOC2B/VAMP2/SYT4/RAB3A/SYT3/PRKCG/SYT5/RIMS4/ITGB2/SEPTIN5/PLA2G3/SYN1/SYP/IL13RA2 | 39 |
| RICKMAN_HEAD_AND_NECK_CANCER_A | RICKMAN_HEAD_AND_NECK_CANCER_A | RICKMAN_HEAD_AND_NECK_CANCER_A | 27/1243 | 105/23056 | 0.2571429 | 4.769659 | 9.241794 | 0.0000000 | 0.0000000 | 0.0000000 | RBP7/TSPAN2/ADD2/FRZB/IL17RD/GPR27/CD200/TMEM108/CRACD/ODAM/PARM1/RNF150/FABP6/GABRP/MYB/ZNF704/OLFM1/SYT13/FGF19/STXBP6/CRABP1/ARNT2/LAMA1/BCL2/CECR2/ZNF711/IL13RA2 | 27 |
| GOBP_CALCIUM_ION_REGULATED_EXOCYTOSIS | GOBP_CALCIUM_ION_REGULATED_EXOCYTOSIS | GOBP_CALCIUM_ION_REGULATED_EXOCYTOSIS | 21/1243 | 65/23056 | 0.3230769 | 5.992648 | 9.622084 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SYT11/RAPGEF4/CDK5R2/SYN2/CADPS/RIMS1/STXBP1/ADRA2A/SYT8/SYT13/SYT7/SCAMP5/STX1B/DOC2B/VAMP2/SYT4/UNC13A/RAB3A/SYT3/SYT5 | 21 |
| GOBP_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | GOBP_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | GOBP_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | 39/1243 | 213/23056 | 0.1830986 | 3.396236 | 8.386934 | 0.0000000 | 0.0000000 | 0.0000000 | CHRNB2/NTRK1/NRXN1/CTNNA2/KIF1A/LHFPL4/CAMKV/CLSTN2/SLITRK3/TLR2/LRFN2/ADGRB3/FYN/RELN/NTRK2/C1QL3/SLIT1/NEURL1/SHANK2/VSTM5/DRD2/IL10RA/NECTIN1/PTPRO/TUBA1A/SLC17A8/CUX2/PCDH8/SLITRK1/SLITRK5/ST8SIA2/STX1B/CBLN1/CDK5R1/SRCIN1/SYNDIG1/NLGN3/ZDHHC15/PAK3 | 39 |
| GOBP_ACTION_POTENTIAL | GOBP_ACTION_POTENTIAL | GOBP_ACTION_POTENTIAL | 31/1243 | 143/23056 | 0.2167832 | 4.021041 | 8.650557 | 0.0000000 | 0.0000000 | 0.0000000 | CLDN19/GPR88/CHRNB2/ATP1B1/RYR2/SLC8A1/KCNH7/SCN3A/SCN1A/SCN7A/CHRNA1/SCN5A/CACNA1D/FGF12/ANK2/CNR1/GRIK2/CLCN1/NTRK2/P2RX3/SCN4B/SCN3B/KCNJ8/KCNC2/AKAP6/CALM1/GJD2/CHRNB4/KCNH6/DSC2/SLC8A2 | 31 |
| GOBP_ADULT_BEHAVIOR | GOBP_ADULT_BEHAVIOR | GOBP_ADULT_BEHAVIOR | 30/1243 | 136/23056 | 0.2205882 | 4.091619 | 8.631942 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/CHRNB2/CNTN2/ALK/NRXN1/SCN1A/CHL1/GRM2/FGF12/GABRG2/OPRM1/NPY/CNTNAP2/PAX5/TMOD1/DBH/OTOG/SLC1A2/NRXN2/SHANK2/DRD2/PCDH17/SLITRK1/NRXN3/CHRNA3/CHRNB4/ABAT/SHANK1/SEPTIN5/NLGN3 | 30 |
| GOBP_SYNAPSE_ASSEMBLY | GOBP_SYNAPSE_ASSEMBLY | GOBP_SYNAPSE_ASSEMBLY | 35/1243 | 180/23056 | 0.1944444 | 3.606686 | 8.380992 | 0.0000000 | 0.0000000 | 0.0000000 | CHRNB2/NTRK1/NRXN1/ADD2/LHFPL4/BSN/GAP43/CLSTN2/SLITRK3/ADGRL3/TLR2/PCDHB3/PCDHB6/PCDHB10/PCDHB11/GABRG2/ADGRB3/NTRK2/SLIT1/NRXN2/SHANK2/VSTM5/DRD2/NECTIN1/CUX2/PCDH17/SLITRK1/SLITRK5/GABRB3/ST8SIA2/CBLN1/SYNDIG1/CBLN4/NLGN3/NLGN4Y | 35 |
| REACTOME_L1CAM_INTERACTIONS | REACTOME_L1CAM_INTERACTIONS | REACTOME_L1CAM_INTERACTIONS | 28/1243 | 121/23056 | 0.2314050 | 4.292255 | 8.667566 | 0.0000000 | 0.0000000 | 0.0000000 | NFASC/CNTN2/TUBA3E/SCN3A/SCN1A/SCN7A/CHL1/CNTN6/SCN5A/GAP43/ANK2/TUBB2A/TUBB2B/CD24/DPYSL2/ANK1/KCNQ3/SCN4B/SCN3B/CNTN1/TUBA1A/TUBA3C/LAMA1/TUBB4A/NCAN/RPS6KA6/DCX/L1CAM | 28 |
| GOMF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 32/1243 | 155/23056 | 0.2064516 | 3.829403 | 8.437114 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/KCNA3/HCN3/KCNJ9/ATP1B1/KCNH1/KCNK3/KCNH7/KCNH8/KCNIP1/GRIK2/KCNB2/KCNQ3/KCNK9/SLC24A2/KCNJ11/KCNC1/KCNK7/GRIK4/KCNJ8/KCNC2/KCNH5/KCNK10/KCNH4/KCNH6/KCNN1/ATP4A/ATP1A3/KCNC3/SNAP25/KCNK15/KCNJ6 | 32 |
| GOBP_MONOAMINE_TRANSPORT | GOBP_MONOAMINE_TRANSPORT | GOBP_MONOAMINE_TRANSPORT | 23/1243 | 83/23056 | 0.2771084 | 5.139994 | 9.019663 | 0.0000000 | 0.0000000 | 0.0000000 | CHRNB2/SYT11/GRM2/CNR1/VIP/SLC18A1/SYK/ADRA2A/SYT8/SYT13/SYT7/DRD2/NOS1/CHGA/ABAT/SLC6A2/SYT4/RAB3A/SYT3/SYT5/HRH3/GPM6B/MAOB | 23 |
| GOMF_POTASSIUM_CHANNEL_ACTIVITY | GOMF_POTASSIUM_CHANNEL_ACTIVITY | GOMF_POTASSIUM_CHANNEL_ACTIVITY | 28/1243 | 122/23056 | 0.2295082 | 4.257072 | 8.610490 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/KCNA3/HCN3/KCNJ9/KCNH1/KCNK3/KCNH7/KCNH8/KCNIP1/GRIK2/KCNB2/KCNQ3/KCNK9/KCNJ11/KCNC1/KCNK7/GRIK4/KCNJ8/KCNC2/KCNH5/KCNK10/KCNH4/KCNH6/KCNN1/KCNC3/SNAP25/KCNK15/KCNJ6 | 28 |
| GOBP_MODULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL | GOBP_MODULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL | GOBP_MODULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL | 16/1243 | 39/23056 | 0.4102564 | 7.609712 | 9.861680 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/NRXN1/IGSF11/TMEM108/RIMS1/RELN/GRIN1/CUX2/SLC8A3/CHRNA7/STX1B/CBLN1/CELF4/SLC8A2/SHANK1/NLGN3 | 16 |
| GOMF_LIGAND_GATED_CATION_CHANNEL_ACTIVITY | GOMF_LIGAND_GATED_CATION_CHANNEL_ACTIVITY | GOMF_LIGAND_GATED_CATION_CHANNEL_ACTIVITY | 27/1243 | 115/23056 | 0.2347826 | 4.354906 | 8.609610 | 0.0000000 | 0.0000000 | 0.0000000 | GRIK3/CHRNB2/KCNJ9/RYR2/KCNH7/CHRNA1/ASIC4/CHRND/CHRNA9/GRIK2/CHRNA2/GRIN1/KCNJ11/P2RX3/GRIA4/HTR3A/GRIK4/KCNJ8/P2RX7/CHRNA7/CHRNA3/CHRNB4/CNGB1/KCNH6/KCNN1/KCNJ6/GRIA3 | 27 |
| GOCC_EXCITATORY_SYNAPSE | GOCC_EXCITATORY_SYNAPSE | GOCC_EXCITATORY_SYNAPSE | 18/1243 | 51/23056 | 0.3529412 | 6.546590 | 9.465869 | 0.0000000 | 0.0000000 | 0.0000000 | PDE4B/SYT11/KCNJ9/CNTN6/ATP2B2/BSN/IGSF11/GRIN1/SLC17A8/CBLN1/SHANK1/SHISA7/SYNDIG1/SYP/NLGN3/GRIA3/ATP2B3/NLGN4Y | 18 |
| GOCC_NEURON_PROJECTION_MEMBRANE | GOCC_NEURON_PROJECTION_MEMBRANE | GOCC_NEURON_PROJECTION_MEMBRANE | 19/1243 | 58/23056 | 0.3275862 | 6.076289 | 9.240080 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/HPCA/ADORA1/ATP2B2/GABRG1/ADGRV1/GABRG2/UNC5A/OPRM1/CNTNAP2/KCNC1/SLC1A2/KCNC2/GABRA5/GABRG3/MAPT/KCNC3/SHISA7/LAMP5 | 19 |
| GOCC_SCHAFFER_COLLATERAL_CA1_SYNAPSE | GOCC_SCHAFFER_COLLATERAL_CA1_SYNAPSE | GOCC_SCHAFFER_COLLATERAL_CA1_SYNAPSE | 21/1243 | 72/23056 | 0.2916667 | 5.410030 | 8.946545 | 0.0000000 | 0.0000000 | 0.0000000 | PRKCZ/NTNG1/TNR/SYN2/BSN/CPLX1/TUBB2B/LRFN2/FYN/INA/LRRC4C/P2RX3/CHRM1/GRM5/GSG1L/DCC/SHANK1/NEFH/CACNG2/SYN1/SYP | 21 |
| GOBP_REGULATION_OF_HORMONE_LEVELS | GOBP_REGULATION_OF_HORMONE_LEVELS | GOBP_REGULATION_OF_HORMONE_LEVELS | 64/1243 | 499/23056 | 0.1282565 | 2.378988 | 7.434137 | 0.0000000 | 0.0000000 | 0.0000000 | ADORA1/TPO/SOX11/VSNL1/RAPGEF4/KLF7/ABCA12/PTPRN/MYRIP/GPR27/ADCY5/RBP1/AGTR1/CPA3/BCHE/ECE2/CPLX1/PDGFRA/ADH4/ISL1/SOX4/GPLD1/TFAP2B/CNR1/SLC16A10/RFX6/ESR1/VIP/ICA1/TFR2/PTPRN2/CPQ/ALDH1A1/ADRA2A/PRLHR/BRSK2/KCNJ11/SYT7/GAL/DRD2/SLCO1B1/IRS2/DHRS2/CHGA/DIO3/DUOXA1/DUOX1/CPLX3/CRABP1/ABAT/EXOC3L1/SMPD3/DOC2B/VAMP2/ACE/CHST9/MC4R/CHST8/SNAP25/EDN3/PLA2G3/ASMT/PNPLA4/PCSK1N | 64 |
| REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES | REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES | REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES | 23/1243 | 87/23056 | 0.2643678 | 4.903672 | 8.708078 | 0.0000000 | 0.0000000 | 0.0000000 | DLGAP3/PPFIA4/NRXN1/SLITRK3/LRFN2/DLGAP2/STXBP1/GRIN1/PPFIBP2/SYT7/NRXN2/SHANK2/GRM5/GRIA4/SLITRK1/SLITRK5/NRXN3/BEGAIN/PPFIA3/SHANK1/NLGN3/GRIA3/NLGN4Y | 23 |
| GOBP_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | GOBP_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | GOBP_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 58/1243 | 431/23056 | 0.1345708 | 2.496109 | 7.484590 | 0.0000000 | 0.0000000 | 0.0000000 | ELAVL4/LRRC7/PLPPR5/NTNG1/NGF/CHRNB2/NTRK1/TNR/CNTN2/ALK/BCL11A/CTNNA2/MAP2/KIF1A/NEU4/SEMA5B/POU4F2/SFRP2/FSTL4/PACSIN1/ADGRB3/CNR1/FUT9/POU3F2/FYN/GPC2/RELN/LZTS1/NTRK2/ROR2/SLIT1/BRSK2/LRRC4C/MAP6/PTPRO/CNTN1/CUX2/ATP8A2/SLITRK1/ISLR2/CHRNA3/STX1B/RTN4RL1/CDK5R1/SRCIN1/MAPT/RIT2/DCC/BRSK1/SNAP25/BMP7/CHODL/TIAM1/INPP5J/PLA2G3/ZDHHC15/PAK3/L1CAM | 58 |
| WP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS | WP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS | WP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS | 32/1243 | 162/23056 | 0.1975309 | 3.663935 | 8.122333 | 0.0000000 | 0.0000000 | 0.0000000 | NGF/CHRNB2/RYR2/MAP2/FEV/SCN5A/GATA2/SOX2/POU3F2/MYB/ADCYAP1R1/DDC/VIPR2/NTRK2/GRIN1/CHAT/TH/HTR3A/SCN4B/SCN3B/KCNJ8/TPH2/PAH/ASCL1/CHRFAM7A/CHRNA7/CHRNB4/VAMP2/SSTR2/ATP1A3/POU2F2/SNAP25 | 32 |
| GOCC_POSTSYNAPTIC_DENSITY_MEMBRANE | GOCC_POSTSYNAPTIC_DENSITY_MEMBRANE | GOCC_POSTSYNAPTIC_DENSITY_MEMBRANE | 23/1243 | 88/23056 | 0.2613636 | 4.847949 | 8.633153 | 0.0000000 | 0.0000000 | 0.0000000 | OPRD1/PLPPR4/KCNH1/ATP2B2/CLSTN2/LRFN2/SORCS3/ADRA2A/LRRC4C/CHRM1/CNIH2/GRM5/PTPRO/SLITRK1/GSG1L/CACNG5/CACNG4/DCC/CACNG7/SHISA7/SYNDIG1/CACNG2/NLGN4Y | 23 |
| GOBP_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS | GOBP_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS | GOBP_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS | 38/1243 | 220/23056 | 0.1727273 | 3.203862 | 7.840542 | 0.0000000 | 0.0000000 | 0.0000000 | CLDN19/ABCA4/CHRNB2/RGS16/RD3/PCARE/SIX3/CRYGC/CRYGB/CRYBA2/ARL6/SEMA5B/BFSP2/PDE6B/ADGRV1/GRM6/GUCA1A/RIMS1/GABRR2/GRM8/RP1L1/SLC24A2/CDH23/OPN4/TH/USH1C/CABP1/ATP8A2/GRK1/GJD2/CLN6/CPLX3/CNGB1/GUCY2D/PRCD/CRYBB1/RS1/CACNA1F | 38 |
| GOBP_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT | GOBP_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT | GOBP_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT | 24/1243 | 99/23056 | 0.2424242 | 4.496648 | 8.322856 | 0.0000000 | 0.0000000 | 0.0000000 | RIMS3/SYT11/CPLX1/CPLX2/RIMS1/CNR1/STXBP1/ADRA2A/DRD2/SLC4A8/NOS1/CPLX3/CHRNA3/CHRNB4/MCTP2/STX1B/SYT4/RAB3A/PRKCG/RIMS4/SEPTIN5/GPM6B/SYN1/SYP | 24 |
| REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | 17/1243 | 51/23056 | 0.3333333 | 6.182891 | 8.845176 | 0.0000000 | 0.0000001 | 0.0000001 | PPFIA4/SLC6A11/SLC6A1/SYN2/CPLX1/RIMS1/STXBP1/CHAT/SLC1A2/ABAT/VAMP2/SLC1A6/RAB3A/PPFIA3/SNAP25/SLC32A1/SYN1 | 17 |
| GOCC_NEURON_SPINE | GOCC_NEURON_SPINE | GOCC_NEURON_SPINE | 32/1243 | 173/23056 | 0.1849711 | 3.430968 | 7.661368 | 0.0000000 | 0.0000001 | 0.0000001 | OPRD1/HPCA/PDE4B/SYT11/ADORA1/SLC8A1/ATP2B2/OPRM1/LZTS1/CALB1/NTRK2/GRIN1/PSD/NEURL1/P2RX3/CNIH2/SHANK2/GRM5/GRIA4/DRD2/PTPRO/RPH3A/NOS1/SLC8A3/CDK5R1/MAPT/SLC8A2/KCNC3/SHANK1/SHISA7/SYNDIG1/GRIA3 | 32 |
| DOANE_BREAST_CANCER_ESR1_UP | DOANE_BREAST_CANCER_ESR1_UP | DOANE_BREAST_CANCER_ESR1_UP | 25/1243 | 111/23056 | 0.2252252 | 4.177629 | 8.010896 | 0.0000000 | 0.0000001 | 0.0000001 | VAV3/C1orf21/GREB1/CACNA1D/CLSTN2/BMPR1B/ELOVL2/MYB/ESR1/AZGP1/DUSP4/FBP1/DNAJC12/GFRA1/SLC4A8/DACH1/DHRS2/SERPINA5/SLC27A2/ABAT/MAPT/CACNG4/BCL2/PRR36/PNPLA4 | 25 |
| MIKKELSEN_IPS_WITH_HCP_H3K27ME3 | MIKKELSEN_IPS_WITH_HCP_H3K27ME3 | MIKKELSEN_IPS_WITH_HCP_H3K27ME3 | 24/1243 | 103/23056 | 0.2330097 | 4.322021 | 8.066064 | 0.0000000 | 0.0000001 | 0.0000001 | VSNL1/SIX3/EVX2/WNT10A/ZMYND10/SLITRK3/FGF12/ADGRL3/KCNIP1/TFAP2D/TFAP2B/ACTL6B/GRM8/CALB1/KCNK9/SORCS3/IL10RA/HOXC10/RPH3A/CA10/TBX4/ZNF536/CACNG2/MPPED1 | 24 |
| REACTOME_POTASSIUM_CHANNELS | REACTOME_POTASSIUM_CHANNELS | REACTOME_POTASSIUM_CHANNELS | 24/1243 | 103/23056 | 0.2330097 | 4.322021 | 8.066064 | 0.0000000 | 0.0000001 | 0.0000001 | KCNA3/HCN3/KCNJ9/KCNH1/GNG4/KCNK3/KCNH7/KCNH8/KCNB2/KCNQ3/KCNK9/KCNJ11/KCNC1/KCNK7/KCNJ8/KCNC2/KCNH5/KCNK10/KCNH4/KCNH6/KCNN1/GNG8/KCNC3/KCNJ6 | 24 |
| WP_SYNAPTIC_VESICLE_PATHWAY | WP_SYNAPTIC_VESICLE_PATHWAY | WP_SYNAPTIC_VESICLE_PATHWAY | 17/1243 | 52/23056 | 0.3269231 | 6.063989 | 8.726763 | 0.0000000 | 0.0000001 | 0.0000001 | SYN2/CPLX1/CPLX2/RIMS1/SLC18A1/STXBP1/CACNA1B/SLC17A8/CPLX3/STX1B/VAMP2/UNC13A/RAB3A/SNAP25/SLC32A1/SYN1/SYP | 17 |
| GOBP_LOCOMOTORY_BEHAVIOR | GOBP_LOCOMOTORY_BEHAVIOR | GOBP_LOCOMOTORY_BEHAVIOR | 34/1243 | 193/23056 | 0.1761658 | 3.267642 | 7.551738 | 0.0000000 | 0.0000001 | 0.0000001 | OPRD1/TAL1/ELAVL4/GPR88/CHRNB2/TNR/CNTN2/ALK/MEIS1/SCN1A/CHL1/ADCY5/FGF12/NPY2R/SELENOP/GRM6/RELN/CALB1/TMOD1/DBH/CDH23/TH/OTOG/SHANK2/GRM5/DRD2/CNTN1/CLN6/CHRNA3/CHRNB4/ABAT/C1QL1/PAK5/SNAP25 | 34 |
| GOBP_TRANSMISSION_OF_NERVE_IMPULSE | GOBP_TRANSMISSION_OF_NERVE_IMPULSE | GOBP_TRANSMISSION_OF_NERVE_IMPULSE | 20/1243 | 73/23056 | 0.2739726 | 5.081828 | 8.338217 | 0.0000000 | 0.0000001 | 0.0000001 | CLDN19/GPR88/TNR/NFASC/SCN3A/SCN1A/SCN7A/CHRNA1/SCN5A/FGF12/GRIK2/CLCN1/CNTNAP2/NTRK2/P2RX3/CHRNB4/CACNG5/CACNG4/CACNG7/CACNG2 | 20 |
| GOBP_DETECTION_OF_ABIOTIC_STIMULUS | GOBP_DETECTION_OF_ABIOTIC_STIMULUS | GOBP_DETECTION_OF_ABIOTIC_STIMULUS | 28/1243 | 138/23056 | 0.2028986 | 3.763499 | 7.772682 | 0.0000000 | 0.0000001 | 0.0000001 | ABCA4/GPR88/NTRK1/ADORA1/CXCR4/SCN1A/SEMA5B/PDE6B/CHRNA9/KIT/ADGRV1/GRM6/LHFPL5/GUCA1A/GRIK2/FYN/SLC24A2/DRGX/OPN4/ATP8A2/GRK1/STRC/CNGB1/GUCY2D/TMC2/PKDREJ/RS1/CACNA1F | 28 |
| GOBP_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | 49/1243 | 353/23056 | 0.1388102 | 2.574745 | 7.117318 | 0.0000000 | 0.0000001 | 0.0000001 | NPPA/HPCA/PDE4B/ATP1B1/RYR2/RGS7/SLC8A1/DPP10/SCN5A/CACNA1D/COX17/FGF12/ANK2/KCNIP1/FYN/OPRM1/TWIST1/RELN/ADRA2A/KCNC1/CNIH2/GAL/DRD2/SCN4B/SCN3B/KCNC2/NOS1/FGF14/JPH4/AKAP6/HSPA2/CALM1/GSG1L/JPH3/FGF11/VAMP2/CACNG5/CACNG4/CACNG1/JSRP1/HRC/SHANK1/CACNG7/SHISA7/TMC2/EDN3/CACNG2/MAPK8IP2/NLGN3 | 49 |
| REACTOME_MUSCLE_CONTRACTION | REACTOME_MUSCLE_CONTRACTION | REACTOME_MUSCLE_CONTRACTION | 34/1243 | 195/23056 | 0.1743590 | 3.234128 | 7.478906 | 0.0000000 | 0.0000001 | 0.0000001 | NPPA/ATP1B1/RYR2/KCNK3/SLC8A1/DYSF/SCN3A/SCN1A/SCN7A/ATP2B2/SCN5A/CACNA2D2/FGF12/GUCY1A1/KCNIP1/KCNK9/TMOD1/SORBS1/KCNJ11/KCNK7/SCN4B/SCN3B/NOS1/FGF14/SLC8A3/KCNK10/CALM1/FGF11/CACNG4/ATP1A3/SLC8A2/CACNG7/KCNK15/ATP2B3 | 34 |
| GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_DENSITY_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_DENSITY_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_POSTSYNAPTIC_DENSITY_MEMBRANE | 17/1243 | 53/23056 | 0.3207547 | 5.949574 | 8.611404 | 0.0000000 | 0.0000001 | 0.0000001 | OPRD1/PLPPR4/ATP2B2/CLSTN2/LRFN2/SORCS3/ADRA2A/LRRC4C/CHRM1/CNIH2/PTPRO/SLITRK1/GSG1L/CACNG4/DCC/CACNG7/CACNG2 | 17 |
| GOBP_MEMORY | GOBP_MEMORY | GOBP_MEMORY | 26/1243 | 122/23056 | 0.2131148 | 3.952996 | 7.806624 | 0.0000000 | 0.0000001 | 0.0000001 | PRKCZ/NGF/CHRNB2/SYT11/SLC6A1/CNR1/RELN/CALB1/SLC24A2/BRINP1/DBH/SORCS3/TH/DRD2/CUX2/SLC8A3/KCNK10/CHRNA7/JPH3/MAPT/SYT4/SLC8A2/SHANK1/SHISA7/PAK5/S100B | 26 |
| GOBP_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | GOBP_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | GOBP_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | 28/1243 | 140/23056 | 0.2000000 | 3.709735 | 7.676827 | 0.0000000 | 0.0000002 | 0.0000001 | RIMS3/SYT11/CDK5R2/GATA2/CNR1/SYK/STXBP1/ADRA2A/SYT8/SYT13/SPI1/SYT7/DRD2/SLC4A8/SCAMP5/DOC2B/SYT4/RAB3A/SYT3/PRKCG/SYT5/RIMS4/ITGB2/SEPTIN5/PLA2G3/SYN1/SYP/IL13RA2 | 28 |
| GOBP_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | GOBP_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | GOBP_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 31/1243 | 170/23056 | 0.1823529 | 3.382405 | 7.442443 | 0.0000000 | 0.0000002 | 0.0000002 | IGSF21/CADM3/CNTN2/CNTN6/CNTN4/CELSR3/IGSF11/CLSTN2/DCHS2/PCDHA1/PCDHB3/PCDHB6/PCDHB10/PCDHB11/PCDHB12/PCDH1/CDHR2/CDH23/CDHR1/FAT3/DSCAML1/NECTIN1/PCDH8/PCDH17/DSC2/DSC1/CDH7/VSTM2L/PTPRT/CDH22/L1CAM | 31 |
| GOBP_PROTEIN_LOCALIZATION_TO_EXTRACELLULAR_REGION | GOBP_PROTEIN_LOCALIZATION_TO_EXTRACELLULAR_REGION | GOBP_PROTEIN_LOCALIZATION_TO_EXTRACELLULAR_REGION | 49/1243 | 359/23056 | 0.1364903 | 2.531713 | 6.982337 | 0.0000000 | 0.0000002 | 0.0000002 | RSAD2/VSNL1/RAPGEF4/KLF7/ABCA12/PTPRN/MYRIP/GPR27/CD200/STXBP5L/ADCY5/CPLX1/TLR2/ISL1/RAB3C/SOX4/GPLD1/TFAP2B/CNR1/RFX6/VIP/OPRM1/ICA1/PTPRN2/DMTN/ADRA2A/BRSK2/KCNJ11/SYT7/GAL/DRD2/PLA2G1B/P2RX7/IRS2/CHGA/CPLX3/ABAT/CBLN1/PARD6A/DOC2B/SRCIN1/PPY/SYT4/MC4R/DAND5/RAB3A/SNAP25/CBLN4/ABCG1 | 49 |
| LEIN_NEURON_MARKERS | LEIN_NEURON_MARKERS | LEIN_NEURON_MARKERS | 19/1243 | 69/23056 | 0.2753623 | 5.107606 | 8.157039 | 0.0000000 | 0.0000002 | 0.0000002 | RYR2/ADD2/UNC80/PTPRN/GAP43/CPLX1/NSG2/PACSIN1/CHST1/GRIA4/FAIM2/SLC22A17/RTN1/DISP2/CHGB/SNAP25/SYP/BEX1/GRIA3 | 19 |
| GOBP_POSITIVE_REGULATION_OF_ION_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_ION_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_ION_TRANSPORT | 41/1243 | 273/23056 | 0.1501832 | 2.785698 | 7.085073 | 0.0000000 | 0.0000003 | 0.0000002 | NPPA/CHRNB2/ATP1B1/ADORA1/RYR2/RGS7/SLC6A1/SCN5A/SLC38A3/CACNA1D/COX17/FGF12/ANK2/GRM6/ADCYAP1R1/RELN/STXBP1/GRIN1/ADRA2A/KCNC1/P2RX3/CHRM1/GAL/DRD2/SCN4B/SCN3B/CNTN1/KCNC2/NOS1/PLA2G1B/P2RX7/AKAP6/HSPA2/CALM1/ABAT/CACNG4/SYT4/EDN3/PLA2G3/CACNG2/NLGN3 | 41 |
| GOBP_CALCIUM_ION_REGULATED_EXOCYTOSIS_OF_NEUROTRANSMITTER | GOBP_CALCIUM_ION_REGULATED_EXOCYTOSIS_OF_NEUROTRANSMITTER | GOBP_CALCIUM_ION_REGULATED_EXOCYTOSIS_OF_NEUROTRANSMITTER | 10/1243 | 17/23056 | 0.5882353 | 10.910984 | 9.758203 | 0.0000000 | 0.0000003 | 0.0000002 | RIMS3/RIMS1/STXBP1/SYT8/SYT7/STX1B/DOC2B/SYT4/UNC13A/SYT5 | 10 |
| SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | 53/1243 | 409/23056 | 0.1295844 | 2.403618 | 6.837000 | 0.0000000 | 0.0000003 | 0.0000003 | PTGER3/NTNG1/TSPAN2/PROX1/GALNT14/MEIS1/ARHGAP25/DPP10/PDE1A/KLF7/CAMKV/IL17RD/SEMA5B/CRACD/ADGRL3/PARM1/GUCY1A1/PHACTR1/LRFN2/BACH2/MYB/ESR1/PACRG/SOX7/ZMAT4/ZNF704/KCNK9/NTRK2/TSPAN18/SYT13/RERG/CNTN1/TMEM132C/SLITRK1/STXBP6/GABRG3/CRABP1/MFAP4/RHBDL3/TMEM132E/WFIKKN2/CHST9/DCC/TCF4/ONECUT2/SLC1A6/ZNF536/WFDC2/EYA2/PREX1/GPM6B/NR0B1/GPRASP1 | 53 |
| GOBP_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_REGULATION_OF_NEURON_DIFFERENTIATION | 33/1243 | 192/23056 | 0.1718750 | 3.188053 | 7.267630 | 0.0000000 | 0.0000003 | 0.0000003 | DISP3/RAP1GAP/NGF/BRINP2/CNTN2/PROX1/SOX11/ALK/SIX3/BCL11A/MEIS1/HOXD3/CNTN4/GATA2/SOX2/POU4F2/SFRP2/ISL1/DLL1/MMD2/DPYSL2/EYA1/BRINP1/ASCL1/DTX1/DUOXA1/RNF112/CDK5R1/TCF4/BCL2/ZNF536/BMP7/TIAM1 | 33 |
| GOBP_ADENYLATE_CYCLASE_INHIBITING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_ADENYLATE_CYCLASE_INHIBITING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_ADENYLATE_CYCLASE_INHIBITING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 20/1243 | 78/23056 | 0.2564103 | 4.756070 | 7.932047 | 0.0000000 | 0.0000004 | 0.0000003 | OPRD1/GRIK3/ADORA1/CHRM3/OXER1/GRM2/ADCY5/NPY2R/GRM6/GRM4/HTR1E/OPRM1/GRM8/ADRA2A/CHRM1/PDE2A/GRM5/DRD2/SSTR2/HRH3 | 20 |
| GOBP_ADENYLATE_CYCLASE_MODULATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_ADENYLATE_CYCLASE_MODULATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_ADENYLATE_CYCLASE_MODULATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 38/1243 | 244/23056 | 0.1557377 | 2.888728 | 7.080159 | 0.0000000 | 0.0000004 | 0.0000003 | OPRD1/GRIK3/PDE4B/PTGER3/ADORA1/CHRM3/OXER1/RAPGEF4/GRM2/CACNA1D/ADCY5/ADGRL3/NPY2R/GRM6/GRM4/GLP1R/ADGRB3/MRAP2/HTR1E/CNR1/VIP/OPRM1/ADCYAP1R1/GRM8/VIPR2/ADRA2A/GPR26/CALCB/CHRM1/PDE2A/GRM5/DRD2/GPR12/CHGA/SSTR2/RIT2/MC4R/HRH3 | 38 |
| REACTOME_PHASE_0_RAPID_DEPOLARISATION | REACTOME_PHASE_0_RAPID_DEPOLARISATION | REACTOME_PHASE_0_RAPID_DEPOLARISATION | 13/1243 | 32/23056 | 0.4062500 | 7.535398 | 8.831146 | 0.0000000 | 0.0000004 | 0.0000003 | SCN3A/SCN1A/SCN7A/SCN5A/CACNA2D2/FGF12/SCN4B/SCN3B/FGF14/CALM1/FGF11/CACNG4/CACNG7 | 13 |
| GOBP_CATECHOLAMINE_SECRETION | GOBP_CATECHOLAMINE_SECRETION | GOBP_CATECHOLAMINE_SECRETION | 17/1243 | 57/23056 | 0.2982456 | 5.532060 | 8.177848 | 0.0000000 | 0.0000004 | 0.0000004 | CHRNB2/SYT11/GRM2/CNR1/VIP/ADRA2A/SYT8/SYT13/SYT7/DRD2/CHGA/ABAT/SYT4/RAB3A/SYT3/SYT5/HRH3 | 17 |
| REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE | 10/1243 | 18/23056 | 0.5555556 | 10.304818 | 9.427188 | 0.0000000 | 0.0000006 | 0.0000005 | PPFIA4/SYN2/CPLX1/RIMS1/STXBP1/VAMP2/RAB3A/PPFIA3/SNAP25/SYN1 | 10 |
| GOBP_HORMONE_TRANSPORT | GOBP_HORMONE_TRANSPORT | GOBP_HORMONE_TRANSPORT | 42/1243 | 293/23056 | 0.1433447 | 2.658854 | 6.821622 | 0.0000000 | 0.0000007 | 0.0000006 | ADORA1/SOX11/VSNL1/RAPGEF4/KLF7/ABCA12/PTPRN/MYRIP/GPR27/ADCY5/AGTR1/CPLX1/ISL1/SOX4/GPLD1/TFAP2B/CNR1/SLC16A10/RFX6/VIP/ICA1/TFR2/PTPRN2/ADRA2A/BRSK2/KCNJ11/SYT7/GAL/DRD2/SLCO1B1/IRS2/CHGA/CPLX3/ABAT/EXOC3L1/SMPD3/DOC2B/VAMP2/MC4R/SNAP25/EDN3/PLA2G3 | 42 |
| GOMF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 28/1243 | 150/23056 | 0.1866667 | 3.462419 | 7.222597 | 0.0000000 | 0.0000007 | 0.0000006 | GRIK3/HCN3/ATP1B1/SLC8A1/SCN3A/SCN1A/SCN7A/ASIC4/SLC6A11/SLC6A1/SCN5A/SLC10A4/GRIK2/SLC18A1/SLC24A2/SLC6A5/SLC1A2/SCN4B/GRIK4/SCN3B/SLC4A8/SLC6A15/SLC8A3/SLC6A2/SLC1A6/ATP4A/ATP1A3/SLC8A2 | 28 |
| GOBP_REGULATION_OF_TRANSPORTER_ACTIVITY | GOBP_REGULATION_OF_TRANSPORTER_ACTIVITY | GOBP_REGULATION_OF_TRANSPORTER_ACTIVITY | 43/1243 | 305/23056 | 0.1409836 | 2.615059 | 6.777951 | 0.0000000 | 0.0000007 | 0.0000006 | NPPA/HPCA/PDE4B/ATP1B1/RYR2/CHRM3/CACNA1D/COX17/FGF12/ANK2/OPRM1/TWIST1/RELN/ADRA2A/KCNC1/CNIH2/GAL/GRM5/DRD2/SCN4B/SCN3B/KCNC2/NOS1/FGF14/JPH4/AKAP6/HSPA2/CALM1/GSG1L/JPH3/FGF11/VAMP2/CACNG5/CACNG4/BCL2/JSRP1/HRC/SHANK1/CACNG7/SHISA7/CACNG2/MAPK8IP2/NLGN3 | 43 |
| GOBP_REGULATION_OF_CATION_CHANNEL_ACTIVITY | GOBP_REGULATION_OF_CATION_CHANNEL_ACTIVITY | GOBP_REGULATION_OF_CATION_CHANNEL_ACTIVITY | 31/1243 | 180/23056 | 0.1722222 | 3.194494 | 7.055714 | 0.0000000 | 0.0000008 | 0.0000007 | NPPA/HPCA/PDE4B/FGF12/ANK2/OPRM1/RELN/KCNC1/CNIH2/GAL/DRD2/KCNC2/NOS1/FGF14/JPH4/AKAP6/CALM1/GSG1L/JPH3/FGF11/VAMP2/CACNG5/CACNG4/JSRP1/HRC/SHANK1/CACNG7/SHISA7/CACNG2/MAPK8IP2/NLGN3 | 31 |
| GOBP_PROTEIN_LOCALIZATION_TO_SYNAPSE | GOBP_PROTEIN_LOCALIZATION_TO_SYNAPSE | GOBP_PROTEIN_LOCALIZATION_TO_SYNAPSE | 18/1243 | 67/23056 | 0.2686567 | 4.983225 | 7.794220 | 0.0000000 | 0.0000009 | 0.0000008 | PRKCZ/NRXN1/KIF5C/GRIP2/BSN/SLITRK3/CPLX1/NSG1/RELN/NRXN2/KIF5A/STX1B/MAPT/SHANK1/CACNG7/SNAP25/CACNG2/ZDHHC15 | 18 |
| GOMF_VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_POTASSIUM_CHANNEL_ACTIVITY | 21/1243 | 91/23056 | 0.2307692 | 4.280463 | 7.484849 | 0.0000000 | 0.0000010 | 0.0000009 | KCNA3/HCN3/KCNJ9/KCNH1/KCNK3/KCNH7/KCNH8/KCNB2/KCNQ3/KCNK9/KCNJ11/KCNC1/KCNJ8/KCNC2/KCNH5/KCNH4/KCNH6/KCNN1/KCNC3/SNAP25/KCNJ6 | 21 |
| REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | 10/1243 | 19/23056 | 0.5263158 | 9.762459 | 9.121164 | 0.0000000 | 0.0000011 | 0.0000009 | SLC6A11/SLC6A1/CPLX1/RIMS1/STXBP1/ABAT/VAMP2/RAB3A/SNAP25/SLC32A1 | 10 |
| GOMF_EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | 12/1243 | 29/23056 | 0.4137931 | 7.675313 | 8.586425 | 0.0000000 | 0.0000011 | 0.0000010 | CHRNB2/CHRNA1/CHRND/CHRNA9/GLRA3/GRIK2/CHRNA2/P2RX3/P2RX7/CHRNA7/CHRNA3/CHRNB4 | 12 |
| GOBP_HEART_PROCESS | GOBP_HEART_PROCESS | GOBP_HEART_PROCESS | 38/1243 | 258/23056 | 0.1472868 | 2.731975 | 6.678263 | 0.0000000 | 0.0000016 | 0.0000014 | NPPA/CYP2J2/PDE4B/ATP1B1/ADORA1/RYR2/SLC8A1/CXCR4/SCN1A/ATP2B2/SCN5A/CACNA1D/FGF12/ANK2/ISL1/GLP1R/FYN/SGCZ/CELF2/TH/DRD2/SCN4B/SCN3B/KCNJ8/FOXN4/NOS1/GCH1/SLC8A3/CALM1/CHGA/ACE/KCNH6/DSC2/ATP1A3/SLC8A2/HRC/EDN3/ATP2B3 | 38 |
| REACTOME_SENSORY_PROCESSING_OF_SOUND | REACTOME_SENSORY_PROCESSING_OF_SOUND | REACTOME_SENSORY_PROCESSING_OF_SOUND | 19/1243 | 77/23056 | 0.2467532 | 4.576945 | 7.505031 | 0.0000000 | 0.0000016 | 0.0000014 | OTOF/ATP2B2/BSN/CACNA2D2/CACNA1D/CHRNA9/LHFPL5/CDH23/USH1C/OTOG/SLC17A8/CABP1/STRC/VAMP2/RAB3A/TMC2/SNAP25/SYN1/SYP | 19 |
| GOBP_MUSCLE_CONTRACTION | GOBP_MUSCLE_CONTRACTION | GOBP_MUSCLE_CONTRACTION | 46/1243 | 349/23056 | 0.1318052 | 2.444811 | 6.492384 | 0.0000000 | 0.0000017 | 0.0000015 | NPPA/PDE4B/PTGER3/CHRNB2/ATP1B1/ADORA1/RYR2/CHRM3/SLC8A1/CXCR4/SCN1A/SCN7A/CHRNA1/CHRND/GRIP2/SCN5A/CACNA1D/PROK2/FGF12/KIT/ANK2/GUCY1A1/CLCN1/KCNB2/TMOD1/ADRA2A/P2RX3/DRD2/SCN4B/SCN3B/KCNJ8/NOS1/ATP8A2/SLC8A3/CALM1/CHGA/CHRNA3/CHRNB4/ABAT/SSTR2/PVALEF/DSC2/JSRP1/HRC/SULF2/EDN3 | 46 |
| GOBP_PEPTIDE_TRANSPORT | GOBP_PEPTIDE_TRANSPORT | GOBP_PEPTIDE_TRANSPORT | 37/1243 | 249/23056 | 0.1485944 | 2.756229 | 6.651307 | 0.0000000 | 0.0000018 | 0.0000016 | ADORA1/VSNL1/RAPGEF4/KLF7/ABCA12/PTPRN/MYRIP/GPR27/ADCY5/CPLX1/ISL1/SOX4/GPLD1/TFAP2B/CNR1/SLC16A10/RFX6/VIP/ICA1/TFR2/PTPRN2/ADRA2A/BRSK2/KCNJ11/SYT7/GAL/DRD2/IRS2/CHGA/CPLX3/ABAT/EXOC3L1/SMPD3/DOC2B/MC4R/SNAP25/EDN3 | 37 |
| GOBP_POSITIVE_REGULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL | GOBP_POSITIVE_REGULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL | GOBP_POSITIVE_REGULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL | 11/1243 | 25/23056 | 0.4400000 | 8.161416 | 8.552103 | 0.0000000 | 0.0000020 | 0.0000018 | PRKCZ/NRXN1/IGSF11/RIMS1/RELN/GRIN1/CUX2/CHRNA7/STX1B/SHANK1/NLGN3 | 11 |
| GOBP_REGULATION_OF_AMPA_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_AMPA_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_AMPA_RECEPTOR_ACTIVITY | 11/1243 | 25/23056 | 0.4400000 | 8.161416 | 8.552103 | 0.0000000 | 0.0000020 | 0.0000018 | RELN/CNIH2/GSG1L/CACNG5/CACNG4/SHANK1/CACNG7/SHISA7/CACNG2/MAPK8IP2/NLGN3 | 11 |
| MIKKELSEN_MEF_ICP_WITH_H3K27ME3 | MIKKELSEN_MEF_ICP_WITH_H3K27ME3 | MIKKELSEN_MEF_ICP_WITH_H3K27ME3 | 33/1243 | 208/23056 | 0.1586538 | 2.942818 | 6.718931 | 0.0000000 | 0.0000021 | 0.0000018 | LINGO4/KCNJ9/RGS8/SCN1A/CFAP65/PLCXD3/NSG2/PHACTR1/GUCA1A/TFAP2B/SOGA3/ELMO1/PHYHIP/RLN1/PAX5/CALCB/FAIM2/CUX2/SLITRK1/TMEM63C/KCNK10/CKMT1A/ISLR2/ARID3B/CPLX3/CHRNB4/ATCAY/NCAN/POU2F2/SYT3/GDAP1L1/SLC38A5/TBX22 | 33 |
| GOBP_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 27/1243 | 149/23056 | 0.1812081 | 3.361169 | 6.902342 | 0.0000000 | 0.0000022 | 0.0000020 | HPCA/RD3/PROX1/SIX3/ATP2B2/PDE6B/PROM1/PDGFRA/BMPR1B/POU4F2/GRM6/TFAP2B/DLL1/RP1L1/CALB1/NTRK2/VSTM4/USH1C/NECTIN1/SLC17A8/FOXN4/ATP8A2/DIO3/LAMA1/CELF4/RS1/DCX | 27 |
| GOBP_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | GOBP_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | GOBP_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | 18/1243 | 71/23056 | 0.2535211 | 4.702480 | 7.458648 | 0.0000000 | 0.0000022 | 0.0000020 | GRIK3/SYT11/TNR/ADORA1/SLC6A1/BCHE/GRIK2/GRID2IP/SLC24A2/STXBP1/SORCS3/SHANK2/DRD2/PCDH17/CBLN1/MAPT/CELF4/SYT4 | 18 |
| HOELZEL_NF1_TARGETS_UP | HOELZEL_NF1_TARGETS_UP | HOELZEL_NF1_TARGETS_UP | 26/1243 | 140/23056 | 0.1857143 | 3.444754 | 6.926122 | 0.0000000 | 0.0000024 | 0.0000021 | RGS16/RGS13/SYT14/CHRM3/NRXN1/OSBPL6/MAP2/KCNH8/GAP43/CLSTN2/ODAM/ANK2/GUCY1A1/RAB3C/GRIK2/RELN/SLC18A1/DUSP4/TSPAN18/SESN3/PCDH17/EDN3/DGKK/CAPN6/SEPTIN6/ARHGAP36 | 26 |
| GOBP_INSULIN_SECRETION | GOBP_INSULIN_SECRETION | GOBP_INSULIN_SECRETION | 30/1243 | 179/23056 | 0.1675978 | 3.108716 | 6.760916 | 0.0000000 | 0.0000024 | 0.0000021 | VSNL1/RAPGEF4/KLF7/ABCA12/PTPRN/MYRIP/GPR27/ADCY5/CPLX1/ISL1/SOX4/GPLD1/TFAP2B/CNR1/RFX6/ICA1/PTPRN2/ADRA2A/BRSK2/KCNJ11/SYT7/GAL/DRD2/IRS2/CHGA/CPLX3/ABAT/DOC2B/MC4R/SNAP25 | 30 |
| GOBP_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | GOBP_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | GOBP_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | 23/1243 | 113/23056 | 0.2035398 | 3.775393 | 7.059909 | 0.0000000 | 0.0000025 | 0.0000022 | CHRNB2/TPO/HAND2/SNCB/SLC16A10/NPY/DDC/CPQ/DBH/TH/DRD2/PMEL/TPH2/PAH/KL/GCH1/DIO3/DUOXA1/DUOX1/ABAT/BCL2/ITGB2/MAOB | 23 |
| GOCC_CELL_BODY_MEMBRANE | GOCC_CELL_BODY_MEMBRANE | GOCC_CELL_BODY_MEMBRANE | 12/1243 | 31/23056 | 0.3870968 | 7.180131 | 8.219382 | 0.0000000 | 0.0000025 | 0.0000022 | HPCA/RGS8/ATP2B2/UNC5A/KCNB2/KCNC1/SLC4A8/KCNC2/GABRA5/SLC6A2/ATP1A3/KCNC3 | 12 |
| GOBP_DOPAMINE_SECRETION | GOBP_DOPAMINE_SECRETION | GOBP_DOPAMINE_SECRETION | 13/1243 | 37/23056 | 0.3513514 | 6.517101 | 8.017316 | 0.0000000 | 0.0000026 | 0.0000023 | CHRNB2/SYT11/GRM2/CNR1/SYT8/SYT13/SYT7/DRD2/ABAT/SYT4/RAB3A/SYT3/SYT5 | 13 |
| GOBP_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 53/1243 | 439/23056 | 0.1207289 | 2.239361 | 6.258542 | 0.0000000 | 0.0000028 | 0.0000025 | NGF/NTRK1/TNR/SOX11/NRXN1/CXCR4/MAP2/HES6/SEMA5B/FAIM/CLSTN2/SLITRK3/KIT/POU4F2/TLR2/FSTL4/TTBK1/ADGRB3/OPRM1/DLL1/FERD3L/RELN/NTRK2/BRINP1/SLIT1/NEURL1/RASSF10/MAP6/GRM5/VSTM5/DRD2/ASCL1/CUX2/SLITRK1/SPINT1/ISLR2/ST8SIA2/CBLN1/RNF112/CDK5R1/MAPT/ACE/SYT4/DCC/DLL3/SYNDIG1/BMP7/CHODL/JAM2/TIAM1/NLGN3/PAK3/L1CAM | 53 |
| GOBP_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | GOBP_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | GOBP_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 39/1243 | 277/23056 | 0.1407942 | 2.611546 | 6.441332 | 0.0000000 | 0.0000032 | 0.0000028 | IGSF21/CLDN19/NTNG1/CADM3/CNTN2/CNTN6/CNTN4/CELSR3/IGSF11/CLSTN2/SLITRK3/ADGRL3/DCHS2/PCDHA1/PCDHB3/PCDHB6/PCDHB10/PCDHB11/PCDHB12/PCDH1/CDHR2/CDH23/CDHR1/LRRC4C/FAT3/DSCAML1/NECTIN1/PCDH8/PCDH17/SLITRK1/CBLN1/DSC2/DSC1/CDH7/VSTM2L/PTPRT/CDH22/ITGB2/L1CAM | 39 |
| LU_AGING_BRAIN_DN | LU_AGING_BRAIN_DN | LU_AGING_BRAIN_DN | 27/1243 | 153/23056 | 0.1764706 | 3.273295 | 6.734662 | 0.0000000 | 0.0000037 | 0.0000033 | GABRD/PRKCZ/KCNJ9/NRXN1/MAP2/ATP2B2/SYN2/TAGLN3/B3GALNT1/FGF12/NSG1/ATP8A1/PARM1/ANK2/CALB1/ELAVL2/PTPRO/CNTN1/CALM1/GABRB3/CDK5R1/MAPT/PPM1E/RAB3A/PRKCG/CHGB/CDH22 | 27 |
| GOBP_AMIDE_TRANSPORT | GOBP_AMIDE_TRANSPORT | GOBP_AMIDE_TRANSPORT | 40/1243 | 290/23056 | 0.1379310 | 2.558438 | 6.375371 | 0.0000000 | 0.0000038 | 0.0000033 | AQP10/ADORA1/VSNL1/RAPGEF4/KLF7/ABCA12/PTPRN/MYRIP/GPR27/ADCY5/CPLX1/ISL1/SOX4/GPLD1/TFAP2B/CNR1/SLC16A10/RFX6/VIP/ICA1/ABCB4/TFR2/PTPRN2/ADRA2A/BRSK2/KCNJ11/SYT7/GAL/DRD2/IRS2/CHGA/CPLX3/ABAT/EXOC3L1/SMPD3/DOC2B/MC4R/SNAP25/EDN3/SLC38A5 | 40 |
| GOBP_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 38/1243 | 269/23056 | 0.1412639 | 2.620259 | 6.380832 | 0.0000001 | 0.0000043 | 0.0000038 | NGF/NTRK1/SOX11/NRXN1/CXCR4/FAIM/CLSTN2/SLITRK3/KIT/POU4F2/TLR2/TTBK1/ADGRB3/OPRM1/RELN/NTRK2/NEURL1/RASSF10/MAP6/GRM5/VSTM5/DRD2/ASCL1/CUX2/SLITRK1/SPINT1/ISLR2/ST8SIA2/CBLN1/RNF112/MAPT/ACE/SYNDIG1/CHODL/TIAM1/NLGN3/PAK3/L1CAM | 38 |
| GOCC_NEUROTRANSMITTER_RECEPTOR_COMPLEX | GOCC_NEUROTRANSMITTER_RECEPTOR_COMPLEX | GOCC_NEUROTRANSMITTER_RECEPTOR_COMPLEX | 14/1243 | 45/23056 | 0.3111111 | 5.770698 | 7.646820 | 0.0000001 | 0.0000044 | 0.0000038 | GRIK3/OLFM3/GRIK2/GRIN1/CNIH2/GRIA4/HTR3A/GRIK4/CACNG5/CACNG4/CACNG7/SHISA7/CACNG2/GRIA3 | 14 |
| GOMF_NEUROTRANSMITTER_BINDING | GOMF_NEUROTRANSMITTER_BINDING | GOMF_NEUROTRANSMITTER_BINDING | 9/1243 | 17/23056 | 0.5294118 | 9.819885 | 8.683924 | 0.0000001 | 0.0000047 | 0.0000041 | CHRNB2/CHRM3/CHRNA1/CHRND/SLC6A11/GRIN1/CHRFAM7A/CHRNA7/CHRNA3 | 9 |
| REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | 9/1243 | 17/23056 | 0.5294118 | 9.819885 | 8.683924 | 0.0000001 | 0.0000047 | 0.0000041 | PPFIA4/CPLX1/RIMS1/STXBP1/CHAT/VAMP2/RAB3A/PPFIA3/SNAP25 | 9 |
| GOCC_DENSE_CORE_GRANULE | GOCC_DENSE_CORE_GRANULE | GOCC_DENSE_CORE_GRANULE | 11/1243 | 27/23056 | 0.4074074 | 7.556867 | 8.137690 | 0.0000001 | 0.0000047 | 0.0000042 | OPRD1/KIF1A/MYRIP/CADPS/NPY/SYT8/SLC6A5/SYT7/CHGA/SYT4/SYT5 | 11 |
| GOMF_GLUTAMATE_RECEPTOR_ACTIVITY | GOMF_GLUTAMATE_RECEPTOR_ACTIVITY | GOMF_GLUTAMATE_RECEPTOR_ACTIVITY | 11/1243 | 27/23056 | 0.4074074 | 7.556867 | 8.137690 | 0.0000001 | 0.0000047 | 0.0000042 | GRIK3/GRM2/GRM6/GRM4/GRIK2/GRM8/GRIN1/GRM5/GRIA4/GRIK4/GRIA3 | 11 |
| GOMF_ACETYLCHOLINE_RECEPTOR_ACTIVITY | GOMF_ACETYLCHOLINE_RECEPTOR_ACTIVITY | GOMF_ACETYLCHOLINE_RECEPTOR_ACTIVITY | 10/1243 | 22/23056 | 0.4545455 | 8.431215 | 8.324284 | 0.0000001 | 0.0000053 | 0.0000047 | CHRNB2/CHRM3/CHRNA1/CHRNA2/CHRM1/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/HRH3 | 10 |
| GOBP_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | 45/1243 | 352/23056 | 0.1278409 | 2.371279 | 6.188800 | 0.0000001 | 0.0000053 | 0.0000047 | HCRTR1/PTGER3/ADORA1/RYR2/KCNK3/SLC8A1/CXCR4/ATP2B2/PROK2/ADCY5/GATA2/AGTR1/KNG1/CHRNA9/PDGFRA/ANK2/SCGN/GLP1R/CNR1/CD24/FYN/ESR1/ADCYAP1R1/CALB1/SLC24A2/GRIN1/CDH23/RIC3/CALCB/P2RX3/GRM5/DRD2/NOS1/PLA2G1B/P2RX7/JPH4/AKAP6/SLC8A3/CALM1/JPH3/BCL2/JSRP1/SLC8A2/HRC/ATP2B3 | 45 |
| GOBP_SENSORY_SYSTEM_DEVELOPMENT | GOBP_SENSORY_SYSTEM_DEVELOPMENT | GOBP_SENSORY_SYSTEM_DEVELOPMENT | 48/1243 | 388/23056 | 0.1237113 | 2.294681 | 6.139493 | 0.0000001 | 0.0000055 | 0.0000048 | HPCA/OLFM3/RD3/PROX1/SOX11/SIX3/MEIS1/CRYGC/CRYGB/CRYBA2/PRSS56/ATP2B2/BFSP2/SOX2/PDE6B/PROM1/PDGFRA/BMPR1B/POU4F2/ISL1/GRM6/TFAP2B/DLL1/TWIST1/RP1L1/CALB1/NTRK2/TMOD1/VSTM4/OPN4/TH/CDKN1C/USH1C/DRD2/NECTIN1/SLC17A8/FOXN4/ATP8A2/DIO3/TMEM132E/LAMA1/CELF4/BCL2/BMP7/CRYBB1/RS1/CHRDL1/DCX | 48 |
| GOBP_REGULATION_OF_BLOOD_CIRCULATION | GOBP_REGULATION_OF_BLOOD_CIRCULATION | GOBP_REGULATION_OF_BLOOD_CIRCULATION | 37/1243 | 261/23056 | 0.1417625 | 2.629505 | 6.319994 | 0.0000001 | 0.0000055 | 0.0000048 | NPPA/CYP2J2/PDE4B/ATP1B1/ADORA1/RYR2/CHRM3/SLC8A1/ATP2B2/SCN5A/CACNA1D/AGTR1/ANK2/ISL1/HRH2/GLP1R/DBH/CELF2/ADRA2A/TH/DRD2/SCN4B/SCN3B/FOXN4/NOS1/GCH1/SLC8A3/CALM1/CHGA/ACE/KCNH6/DSC2/ATP1A3/SLC8A2/HRC/EDN3/ATP2B3 | 37 |
| GOBP_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS | GOBP_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS | GOBP_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS | 29/1243 | 177/23056 | 0.1638418 | 3.039048 | 6.500638 | 0.0000001 | 0.0000061 | 0.0000053 | CHRNB2/NTRK1/OTOF/CXCR4/SCN1A/LHFPL4/ATP2B2/CACNA1D/CHRNA9/KIT/POU4F2/ADGRV1/DCDC2/LHFPL5/FYN/EYA1/DRGX/CDH23/TH/USH1C/OTOG/SLC17A8/SRRM4/GABRA5/STRC/LOXHD1/RAB3A/TMC2/OTOR | 29 |
| GOBP_NEUROMUSCULAR_SYNAPTIC_TRANSMISSION | GOBP_NEUROMUSCULAR_SYNAPTIC_TRANSMISSION | GOBP_NEUROMUSCULAR_SYNAPTIC_TRANSMISSION | 11/1243 | 28/23056 | 0.3928571 | 7.286979 | 7.946087 | 0.0000001 | 0.0000071 | 0.0000063 | CHRNB2/CHRNA1/ERC2/STXBP1/CHAT/P2RX3/CHRM1/RIMBP2/CHRNA3/CHRNB4/RAB3A | 11 |
| SMID_BREAST_CANCER_LUMINAL_A_UP | SMID_BREAST_CANCER_LUMINAL_A_UP | SMID_BREAST_CANCER_LUMINAL_A_UP | 19/1243 | 85/23056 | 0.2235294 | 4.146174 | 6.936856 | 0.0000001 | 0.0000071 | 0.0000063 | PTGER3/DPT/C1orf21/CPA3/ELOVL2/MYB/ESR1/PNMA2/ENPP2/ADRA2A/ATRNL1/GFRA1/DHRS2/RTN1/MFAP4/HLF/LAMP5/CCN5/CHRDL1 | 19 |
| SMID_BREAST_CANCER_LUMINAL_B_UP | SMID_BREAST_CANCER_LUMINAL_B_UP | SMID_BREAST_CANCER_LUMINAL_B_UP | 28/1243 | 169/23056 | 0.1656805 | 3.073153 | 6.457147 | 0.0000001 | 0.0000078 | 0.0000069 | GREB1/KIF5C/CELSR3/CACNA2D2/CACNA1D/CLSTN2/AGTR1/BMPR1B/ZDHHC11/ESR1/FBP1/DNAJC12/GFRA1/ASCL1/DACH1/CHGA/SERPINA5/SLC27A2/ARNT2/ABAT/MAPT/CACNG4/SSTR2/LDLRAD4/SLC8A2/PTPRT/WFDC2/MYT1 | 28 |
| REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | 10/1243 | 23/23056 | 0.4347826 | 8.064640 | 8.091688 | 0.0000001 | 0.0000086 | 0.0000075 | PPFIA4/SYN2/CPLX1/RIMS1/STXBP1/VAMP2/RAB3A/PPFIA3/SNAP25/SYN1 | 10 |
| GOCC_DENDRITE_MEMBRANE | GOCC_DENDRITE_MEMBRANE | GOCC_DENDRITE_MEMBRANE | 13/1243 | 41/23056 | 0.3170732 | 5.881286 | 7.467602 | 0.0000001 | 0.0000093 | 0.0000082 | OPRD1/HPCA/ATP2B2/GABRG1/GABRG2/OPRM1/KCNC1/KCNC2/GABRA5/GABRG3/KCNC3/SHISA7/LAMP5 | 13 |
| GOBP_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | GOBP_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | GOBP_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC | 11/1243 | 29/23056 | 0.3793103 | 7.035703 | 7.763698 | 0.0000002 | 0.0000106 | 0.0000093 | NTRK1/TNR/NRXN1/RELN/ROR2/STXBP1/CACNG5/CACNG4/CACNG7/CACNG2/NLGN3 | 11 |
| REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | 8/1243 | 14/23056 | 0.5714286 | 10.599241 | 8.576326 | 0.0000002 | 0.0000110 | 0.0000097 | CHRNB2/CHRNA1/CHRND/CHRNA9/CHRNA2/CHRNA7/CHRNA3/CHRNB4 | 8 |
| GOBP_RECEPTOR_LOCALIZATION_TO_SYNAPSE | GOBP_RECEPTOR_LOCALIZATION_TO_SYNAPSE | GOBP_RECEPTOR_LOCALIZATION_TO_SYNAPSE | 15/1243 | 56/23056 | 0.2678571 | 4.968394 | 7.097499 | 0.0000002 | 0.0000122 | 0.0000107 | PRKCZ/LRRC7/KIF5C/GRIP2/CPLX1/NSG1/RELN/CNIH2/KIF5A/STX1B/CACNG5/CACNG4/CACNG7/SNAP25/CACNG2 | 15 |
| REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | 10/1243 | 24/23056 | 0.4166667 | 7.728614 | 7.872738 | 0.0000002 | 0.0000136 | 0.0000120 | PPFIA4/CPLX1/RIMS1/STXBP1/SLC1A2/VAMP2/SLC1A6/RAB3A/PPFIA3/SNAP25 | 10 |
| GOBP_CAMERA_TYPE_EYE_DEVELOPMENT | GOBP_CAMERA_TYPE_EYE_DEVELOPMENT | GOBP_CAMERA_TYPE_EYE_DEVELOPMENT | 42/1243 | 329/23056 | 0.1276596 | 2.367916 | 5.965497 | 0.0000002 | 0.0000139 | 0.0000122 | HPCA/RD3/PROX1/SOX11/SIX3/MEIS1/CRYGC/CRYGB/CRYBA2/PRSS56/ATP2B2/BFSP2/PDE6B/PROM1/PDGFRA/BMPR1B/POU4F2/GRM6/TFAP2B/DLL1/TWIST1/RP1L1/CALB1/NTRK2/TMOD1/VSTM4/OPN4/TH/CDKN1C/USH1C/DRD2/NECTIN1/SLC17A8/FOXN4/ATP8A2/DIO3/LAMA1/CELF4/BMP7/CRYBB1/RS1/DCX | 42 |
| REACTOME_GPCR_LIGAND_BINDING | REACTOME_GPCR_LIGAND_BINDING | REACTOME_GPCR_LIGAND_BINDING | 53/1243 | 463/23056 | 0.1144708 | 2.123282 | 5.828447 | 0.0000002 | 0.0000139 | 0.0000122 | HTR6/OPRD1/HCRTR1/PTGER3/PLPPR5/PLPPR4/ACKR1/ADORA1/GNG4/CHRM3/OXER1/PROKR1/CXCR4/WNT10A/GRM2/PROK2/AGTR1/ECE2/KNG1/NPY2R/HRH2/GRM6/GRM4/GLP1R/HTR1E/CNR1/GPRC6A/VIP/OPRM1/NPY/ADCYAP1R1/GRM8/VIPR2/RLN2/PLPPR1/OPN4/ADRA2A/PRLHR/CALCB/CHRM1/GAL/GRM5/DRD2/TAC3/PPY/SSTR2/MC4R/PLPPR3/P2RY11/GNG8/PROKR2/EDN3/HRH3 | 53 |
| GOMF_CHANNEL_REGULATOR_ACTIVITY | GOMF_CHANNEL_REGULATOR_ACTIVITY | GOMF_CHANNEL_REGULATOR_ACTIVITY | 25/1243 | 144/23056 | 0.1736111 | 3.220256 | 6.379889 | 0.0000002 | 0.0000140 | 0.0000123 | PRKCZ/HPCAL4/NRXN1/DPP10/GRM2/FGF12/NPY2R/KCNIP1/GPLD1/NPY/AMBP/NRXN2/SCN4B/SCN3B/NOS1/FGF14/CALM1/CHRNA7/FGF11/CACNG5/CACNG4/CACNG1/BCL2/CACNG7/CACNG2 | 25 |
| GOBP_VOCALIZATION_BEHAVIOR | GOBP_VOCALIZATION_BEHAVIOR | GOBP_VOCALIZATION_BEHAVIOR | 9/1243 | 19/23056 | 0.4736842 | 8.786213 | 8.104954 | 0.0000002 | 0.0000143 | 0.0000126 | NRXN1/CNTNAP2/BRINP1/NRXN2/SHANK2/NRXN3/SHANK1/NLGN3/NLGN4Y | 9 |
| GOCC_POTASSIUM_CHANNEL_COMPLEX | GOCC_POTASSIUM_CHANNEL_COMPLEX | GOCC_POTASSIUM_CHANNEL_COMPLEX | 19/1243 | 89/23056 | 0.2134831 | 3.959829 | 6.678361 | 0.0000002 | 0.0000145 | 0.0000127 | GRIK3/KCNA3/KCNH1/DPP10/KCNIP1/GRIK2/CNTNAP2/KCNB2/KCNQ3/KCNJ11/KCNC1/GRIK4/KCNJ8/KCNC2/CALM1/KCNH4/KCNN1/KCNC3/KCNJ6 | 19 |
| HP_MYOCLONUS | HP_MYOCLONUS | HP_MYOCLONUS | 44/1243 | 354/23056 | 0.1242938 | 2.305485 | 5.908834 | 0.0000002 | 0.0000150 | 0.0000132 | GABRD/DNAJC6/NTNG1/NFASC/CNTN2/MYT1L/SCN3A/SCN1A/KIF1A/SLC6A1/SATB1/ADCY5/FGF12/CPLX1/CTNND2/GABRG2/PHACTR1/GRIK2/DLL1/DDC/ACTL6B/KCNQ3/NTRK2/STXBP1/GRIN1/CACNA1B/CELF2/BRSK2/TH/KCNC1/SLC6A5/SLC1A2/DRD2/KIF5A/CUX2/GABRB3/GABRA5/CLN6/MAPT/TCF4/KCNC3/PRKCG/CACNG2/GRIA3 | 44 |
| GOBP_REGULATION_OF_METAL_ION_TRANSPORT | GOBP_REGULATION_OF_METAL_ION_TRANSPORT | GOBP_REGULATION_OF_METAL_ION_TRANSPORT | 48/1243 | 403/23056 | 0.1191067 | 2.209271 | 5.846202 | 0.0000002 | 0.0000155 | 0.0000137 | NPPA/OPRD1/HPCA/PDE4B/ATP1B1/ADORA1/RYR2/RGS7/SLC8A1/DPP10/CXCR4/SCN5A/CACNA1D/FGF12/ANK2/KCNIP1/GRM6/FYN/VIP/ADCYAP1R1/GRIN1/ADRA2A/KCNC1/P2RX3/GAL/DRD2/SCN4B/SCN3B/CNTN1/KCNC2/NOS1/PLA2G1B/P2RX7/FGF14/JPH4/AKAP6/HSPA2/CALM1/JPH3/FGF11/VAMP2/ACE/CACNG1/BCL2/JSRP1/HRC/TMC2/EDN3 | 48 |
| HP_STATUS_EPILEPTICUS | HP_STATUS_EPILEPTICUS | HP_STATUS_EPILEPTICUS | 30/1243 | 196/23056 | 0.1530612 | 2.839082 | 6.172365 | 0.0000002 | 0.0000155 | 0.0000137 | GABRD/MYT1L/SCN3A/SCN1A/KIF1A/SATB1/FGF12/ADGRV1/GABRG2/DLL1/ACTL6B/KCNQ3/NTRK2/STXBP1/GRIN1/CACNA1B/CELF2/BRSK2/KCNJ11/SLC1A2/PDE2A/GRIA4/GABRA5/STX1B/VAMP2/TCF4/ATP1A3/CACNG2/NEXMIF/GRIA3 | 30 |
| GOBP_REGULATION_OF_NEURONAL_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_NEURONAL_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_NEURONAL_SYNAPTIC_PLASTICITY | 14/1243 | 50/23056 | 0.2800000 | 5.193628 | 7.086223 | 0.0000002 | 0.0000162 | 0.0000143 | CNTN2/KIT/GRIK2/NEURL1/GRM5/DRD2/JPH3/SYT4/RAB3A/SLC8A2/PPFIA3/SHISA7/S100B/SYP | 14 |
| HOELZEL_NF1_TARGETS_DN | HOELZEL_NF1_TARGETS_DN | HOELZEL_NF1_TARGETS_DN | 22/1243 | 117/23056 | 0.1880342 | 3.487785 | 6.439896 | 0.0000003 | 0.0000171 | 0.0000150 | BCL11A/SATB1/CD200/PDGFRA/ADGRL3/C7/LIX1/SCGN/SNAP91/CD24/SLC35D3/RLN2/FAT3/HRK/FAM124A/ST8SIA2/YPEL3/SSTR2/LDLRAD4/RNF165/PAK5/PHACTR3 | 22 |
| GOMF_TRANSMEMBRANE_TRANSPORTER_BINDING | GOMF_TRANSMEMBRANE_TRANSPORTER_BINDING | GOMF_TRANSMEMBRANE_TRANSPORTER_BINDING | 23/1243 | 127/23056 | 0.1811024 | 3.359208 | 6.364086 | 0.0000003 | 0.0000186 | 0.0000163 | RIMS3/PDE4B/RYR2/SLC8A1/DPP10/SCN5A/FGF12/ANK2/KCNIP1/RIMS1/FYN/ANK1/KCNJ11/KCNC1/SCN4B/SCN3B/KCNC2/NOS1/AKAP6/KCNH5/CALM1/HRC/RIMS4 | 23 |
| GOCC_ACETYLCHOLINE_GATED_CHANNEL_COMPLEX | GOCC_ACETYLCHOLINE_GATED_CHANNEL_COMPLEX | GOCC_ACETYLCHOLINE_GATED_CHANNEL_COMPLEX | 8/1243 | 15/23056 | 0.5333333 | 9.892625 | 8.224043 | 0.0000003 | 0.0000208 | 0.0000183 | CHRNB2/CHRNA1/CHRNA9/CHRNA2/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4 | 8 |
| GOBP_DOPAMINE_TRANSPORT | GOBP_DOPAMINE_TRANSPORT | GOBP_DOPAMINE_TRANSPORT | 14/1243 | 51/23056 | 0.2745098 | 5.091793 | 6.983096 | 0.0000003 | 0.0000208 | 0.0000183 | CHRNB2/SYT11/GRM2/CNR1/SYT8/SYT13/SYT7/DRD2/ABAT/SLC6A2/SYT4/RAB3A/SYT3/SYT5 | 14 |
| GOBP_ORGANIC_ACID_TRANSPORT | GOBP_ORGANIC_ACID_TRANSPORT | GOBP_ORGANIC_ACID_TRANSPORT | 41/1243 | 323/23056 | 0.1269350 | 2.354475 | 5.852002 | 0.0000003 | 0.0000211 | 0.0000185 | RBP7/SLC6A17/ADORA1/AGXT/SLC6A11/SLC6A1/SLC38A3/GRM2/RBP1/SLC10A4/ACSL1/SLC25A48/FABP6/SLC16A10/NTRK2/SYK/STXBP1/SLC6A5/SLC1A2/SLC22A6/FGF19/DRD2/SLCO1B1/ABCD2/SLC6A15/SLC17A8/PLA2G1B/P2RX7/IRS2/SLC25A29/SLC27A2/CRABP1/ABAT/ACE/SYT4/SLC1A6/SLC32A1/HRH3/PLA2G3/SLC38A5/SLC7A3 | 41 |
| REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 11/1243 | 31/23056 | 0.3548387 | 6.581787 | 7.423603 | 0.0000003 | 0.0000213 | 0.0000187 | NFASC/SCN3A/SCN1A/SCN7A/SCN5A/ANK2/ANK1/KCNQ3/SCN4B/SCN3B/L1CAM | 11 |
| GOBP_POSITIVE_REGULATION_OF_SECRETION | GOBP_POSITIVE_REGULATION_OF_SECRETION | GOBP_POSITIVE_REGULATION_OF_SECRETION | 39/1243 | 300/23056 | 0.1300000 | 2.411327 | 5.873553 | 0.0000003 | 0.0000216 | 0.0000190 | CHRNB2/ADORA1/SOX11/VSNL1/CDK5R2/SLC6A1/MYRIP/CADPS/GPR27/GATA2/TLR2/ISL1/SOX4/GPLD1/CNR1/RFX6/VIP/TFR2/SYK/STXBP1/SYT7/GAL/DRD2/SLC4A8/PLA2G1B/P2RX7/IRS2/SCAMP5/ABAT/STX1B/PARD6A/SMPD3/DOC2B/SYT4/RAB3A/EDN3/ABCG1/ITGB2/PLA2G3 | 39 |
| GOBP_CELL_JUNCTION_ASSEMBLY | GOBP_CELL_JUNCTION_ASSEMBLY | GOBP_CELL_JUNCTION_ASSEMBLY | 49/1243 | 421/23056 | 0.1163895 | 2.158872 | 5.728574 | 0.0000004 | 0.0000222 | 0.0000195 | CLDN19/CHRNB2/NTRK1/NRXN1/ADD2/LHFPL4/BSN/GAP43/CLSTN2/SLITRK3/ADGRL3/ANK2/UGT8/TLR2/CTNND2/PCDHB3/PCDHB6/PCDHB10/PCDHB11/GABRG2/ADGRB3/CNTNAP2/DMTN/NTRK2/SORBS1/SLIT1/NRXN2/SHANK2/VSTM5/DRD2/NECTIN1/PTPRO/CUX2/PCDH17/SLITRK1/SLITRK5/GABRB3/ST8SIA2/CBLN1/ACE/BCL2/CDH7/CAMSAP3/SYNDIG1/CDH22/CBLN4/GPM6B/NLGN3/NLGN4Y | 49 |
| GOMF_ACETYLCHOLINE_BINDING | GOMF_ACETYLCHOLINE_BINDING | GOMF_ACETYLCHOLINE_BINDING | 7/1243 | 11/23056 | 0.6363636 | 11.803701 | 8.555413 | 0.0000004 | 0.0000222 | 0.0000195 | CHRNB2/CHRM3/CHRNA1/CHRND/CHRFAM7A/CHRNA7/CHRNA3 | 7 |
| REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | 7/1243 | 11/23056 | 0.6363636 | 11.803701 | 8.555413 | 0.0000004 | 0.0000222 | 0.0000195 | CHRNB2/CHRNA1/CHRNA9/CHRNA2/CHRNA7/CHRNA3/CHRNB4 | 7 |
| GOBP_EXOCYTIC_PROCESS | GOBP_EXOCYTIC_PROCESS | GOBP_EXOCYTIC_PROCESS | 17/1243 | 75/23056 | 0.2266667 | 4.204366 | 6.635118 | 0.0000004 | 0.0000233 | 0.0000205 | OTOF/ERC2/CPLX1/RAB3C/CPLX2/DMTN/SYK/STXBP1/CPLX3/STX1B/VAMP2/UNC13A/RAB3A/PPFIA3/SNAP25/SEPTIN5/PLA2G3 | 17 |
| GOBP_REGULATION_OF_HEART_CONTRACTION | GOBP_REGULATION_OF_HEART_CONTRACTION | GOBP_REGULATION_OF_HEART_CONTRACTION | 31/1243 | 212/23056 | 0.1462264 | 2.712306 | 5.978932 | 0.0000004 | 0.0000259 | 0.0000228 | NPPA/CYP2J2/PDE4B/ATP1B1/ADORA1/RYR2/SLC8A1/ATP2B2/SCN5A/CACNA1D/ANK2/ISL1/GLP1R/CELF2/TH/DRD2/SCN4B/SCN3B/FOXN4/NOS1/GCH1/SLC8A3/CALM1/CHGA/KCNH6/DSC2/ATP1A3/SLC8A2/HRC/EDN3/ATP2B3 | 31 |
| GOBP_CALCIUM_ION_TRANSPORT | GOBP_CALCIUM_ION_TRANSPORT | GOBP_CALCIUM_ION_TRANSPORT | 49/1243 | 424/23056 | 0.1155660 | 2.143597 | 5.673548 | 0.0000004 | 0.0000269 | 0.0000236 | NPPA/OPRD1/HPCA/PDE4B/CHRNB2/ATP1B1/RYR2/SLC8A1/CXCR4/ATP2B2/CACNA2D2/CACNA1D/CHRNA9/ANK2/GRM6/FYN/OPRM1/ADCYAP1R1/SLC24A2/GRIN1/CACNA1B/CDH23/ADRA2A/P2RX3/DRD2/NOS1/PLA2G1B/P2RX7/JPH4/AKAP6/HSPA2/SLC8A3/CALM1/CHRNA7/JPH3/ACE/CACNG5/CACNG4/CACNG1/BCL2/JSRP1/SLC8A2/HRC/CACNG7/TMC2/CACNG2/PKDREJ/CACNA1F/ATP2B3 | 49 |
| GOCC_SARCOLEMMA | GOCC_SARCOLEMMA | GOCC_SARCOLEMMA | 23/1243 | 131/23056 | 0.1755725 | 3.256637 | 6.183055 | 0.0000005 | 0.0000310 | 0.0000273 | ATP1B1/RYR2/SLC8A1/DYSF/SCN1A/SCN5A/CACNA1D/ANK2/OPRM1/CLCN1/SGCZ/CAVIN4/KCNJ11/FGF6/KCNJ8/NOS1/AKAP6/SLC8A3/CACNG4/CACNG1/RTN2/SLC8A2/CACNG7 | 23 |
| HATADA_METHYLATED_IN_LUNG_CANCER_UP | HATADA_METHYLATED_IN_LUNG_CANCER_UP | HATADA_METHYLATED_IN_LUNG_CANCER_UP | 45/1243 | 377/23056 | 0.1193634 | 2.214033 | 5.673479 | 0.0000005 | 0.0000318 | 0.0000279 | AJAP1/OTOF/HAAO/DYSF/CNTNAP5/KCNH7/RAPGEF4/HOXD3/FRZB/CACNA2D2/CADPS/AGTR1/PROM1/KIT/ANK2/POU4F2/ZDHHC11/ISL1/ZNF454/MRAP2/ESR1/TWIST1/FERD3L/ENPP2/ELAVL2/FBP1/OLFM1/PRLHR/RIC3/NELL1/ATP8A2/KL/BEGAIN/DUOX1/ADAMTS17/YPEL3/SLC6A2/FGF11/LDLRAD4/P2RY11/ANKLE1/ZNF626/ZIM2/SULF2/DIPK2B | 45 |
| GOBP_DEVELOPMENTAL_MATURATION | GOBP_DEVELOPMENTAL_MATURATION | GOBP_DEVELOPMENTAL_MATURATION | 38/1243 | 294/23056 | 0.1292517 | 2.397448 | 5.756578 | 0.0000006 | 0.0000337 | 0.0000296 | IGSF21/EPHA8/TAL1/CNTN2/RHEX/SIX3/NRXN1/BCL11A/CDK5R2/FEV/PTPRN/ROPN1/ROPN1B/GATA2/BFSP2/SPINK5/ADGRB3/ACTL6B/RELN/CNTNAP2/DEFB1/STXBP1/NEURL1/CDKN1C/GAL/ASCL1/SRRM4/CCDC154/CNGB1/CDK5R1/C1QL1/BCL2/UNC13A/RAB3A/SHANK1/PLA2G3/SYP/ZDHHC15 | 38 |
| NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | 17/1243 | 77/23056 | 0.2207792 | 4.095161 | 6.494168 | 0.0000006 | 0.0000337 | 0.0000296 | SOX11/IGFBP2/ZDHHC11/NTRK2/EPB41L4B/OLFM1/NELL1/SHANK2/B3GAT1/CUX2/RIMBP2/DLK1/CRABP1/EDN3/NEFH/GPM6B/CAPN6 | 17 |
| GOBP_REGULATION_OF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | 15/1243 | 61/23056 | 0.2459016 | 4.561149 | 6.648119 | 0.0000006 | 0.0000354 | 0.0000311 | DLGAP3/OPRM1/RELN/DLGAP2/CNIH2/BEGAIN/GSG1L/CACNG5/CACNG4/SHANK1/CACNG7/SHISA7/CACNG2/MAPK8IP2/NLGN3 | 15 |
| GOMF_ACETYLCHOLINE_GATED_CATION_SELECTIVE_CHANNEL_ACTIVITY | GOMF_ACETYLCHOLINE_GATED_CATION_SELECTIVE_CHANNEL_ACTIVITY | GOMF_ACETYLCHOLINE_GATED_CATION_SELECTIVE_CHANNEL_ACTIVITY | 8/1243 | 16/23056 | 0.5000000 | 9.274336 | 7.903371 | 0.0000006 | 0.0000364 | 0.0000320 | CHRNB2/CHRNA1/CHRND/CHRNA9/CHRNA2/CHRNA7/CHRNA3/CHRNB4 | 8 |
| WP_GABA_RECEPTOR_SIGNALING | WP_GABA_RECEPTOR_SIGNALING | WP_GABA_RECEPTOR_SIGNALING | 11/1243 | 33/23056 | 0.3333333 | 6.182891 | 7.112274 | 0.0000007 | 0.0000411 | 0.0000361 | GABRD/SLC6A11/SLC6A1/GABRG1/GABRG2/GABRP/GABRB3/GABRA5/GABRG3/ABAT/SLC32A1 | 11 |
| GOBP_NEURON_MIGRATION | GOBP_NEURON_MIGRATION | GOBP_NEURON_MIGRATION | 26/1243 | 164/23056 | 0.1585366 | 2.940643 | 5.953690 | 0.0000007 | 0.0000436 | 0.0000384 | NTNG1/CNTN2/CTNNA2/CXCR4/CDK5R2/CHL1/GATA2/ADGRL3/GFRA3/TUBB2A/TUBB2B/PHACTR1/DCDC2/FYN/TWIST1/RELN/SCRT1/NTRK2/DRGX/NRG3/DRD2/ASCL1/CDK5R1/DCC/NEXMIF/DCX | 26 |
| GOBP_PROTEIN_LOCALIZATION_TO_CELL_JUNCTION | GOBP_PROTEIN_LOCALIZATION_TO_CELL_JUNCTION | GOBP_PROTEIN_LOCALIZATION_TO_CELL_JUNCTION | 19/1243 | 96/23056 | 0.1979167 | 3.671091 | 6.260353 | 0.0000007 | 0.0000437 | 0.0000384 | PRKCZ/NRXN1/KIF5C/GRIP2/BSN/SLITRK3/CPLX1/NSG1/RELN/NRXN2/NECTIN1/KIF5A/STX1B/MAPT/SHANK1/CACNG7/SNAP25/CACNG2/ZDHHC15 | 19 |
| GOBP_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | GOBP_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | GOBP_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | 12/1243 | 40/23056 | 0.3000000 | 5.564602 | 6.897289 | 0.0000008 | 0.0000457 | 0.0000401 | SYT11/CDK5R2/STXBP1/ADRA2A/SYT8/SYT13/SYT7/SCAMP5/DOC2B/SYT4/SYT3/SYT5 | 12 |
| GOCC_INTRINSIC_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | 12/1243 | 40/23056 | 0.3000000 | 5.564602 | 6.897289 | 0.0000008 | 0.0000457 | 0.0000401 | OPRD1/SLC6A17/SLC30A3/TMEM163/RAB3C/SLC17A8/CPLX3/SYT4/RAB3A/SLC32A1/SYN1/SYP | 12 |
| GOBP_REGULATION_OF_PROTEIN_SECRETION | GOBP_REGULATION_OF_PROTEIN_SECRETION | GOBP_REGULATION_OF_PROTEIN_SECRETION | 34/1243 | 252/23056 | 0.1349206 | 2.502599 | 5.725299 | 0.0000008 | 0.0000467 | 0.0000411 | RSAD2/VSNL1/KLF7/ABCA12/MYRIP/GPR27/CD200/STXBP5L/ADCY5/TLR2/ISL1/SOX4/GPLD1/TFAP2B/CNR1/RFX6/OPRM1/ICA1/ADRA2A/BRSK2/KCNJ11/SYT7/DRD2/PLA2G1B/P2RX7/IRS2/CHGA/ABAT/PARD6A/DOC2B/SRCIN1/SYT4/SNAP25/ABCG1 | 34 |
| SMID_BREAST_CANCER_NORMAL_LIKE_UP | SMID_BREAST_CANCER_NORMAL_LIKE_UP | SMID_BREAST_CANCER_NORMAL_LIKE_UP | 53/1243 | 484/23056 | 0.1095041 | 2.031156 | 5.472964 | 0.0000008 | 0.0000469 | 0.0000413 | CHRNB2/ACKR1/RGS5/DPT/FNDC4/NRXN1/BCL11A/LGALSL/ARHGAP25/CD8A/FRZB/CHL1/PLCL2/SATB1/VILL/NSG1/PDGFRA/KIT/ODAM/ANK2/C7/SELENOP/SPINK5/FYN/PACRG/ELMO1/RELN/LZTS1/ENPP2/PAX5/ALDH1A1/NTRK2/TMOD1/CELF2/SORBS1/CDKN1C/NRXN2/PDE2A/CD3G/KCTD12/PELI2/SYNE3/DLK1/DOC2B/MFAP4/TCF4/MAP4K1/NKG7/PPP1R16B/EDN3/S100B/TSPAN7/CHRDL1 | 53 |
| RIGGI_EWING_SARCOMA_PROGENITOR_UP | RIGGI_EWING_SARCOMA_PROGENITOR_UP | RIGGI_EWING_SARCOMA_PROGENITOR_UP | 49/1243 | 434/23056 | 0.1129032 | 2.094205 | 5.493365 | 0.0000009 | 0.0000500 | 0.0000439 | PTGER3/OLFM3/NTNG1/NTRK1/RGS5/LRATD1/KCNK3/ALK/MEIS1/CSRNP3/FRZB/IGFBP2/GATA2/CLSTN2/SOX2/SHISA3/KIT/PARM1/SERPINB9/MRAP2/GRIK2/RELN/TMEM178B/TRMT9B/STMN4/ZNF704/CCDC171/BRINP1/PLXDC2/DNAJC12/CALCB/LRRC4C/FAT3/TSPAN11/NOS1/P2RX7/PCDH17/GCH1/TM6SF1/MFAP4/MAPT/TCF4/PPFIA3/MAFB/PREX1/ITGB2/NR0B1/ZNF711/ZCCHC12 | 49 |
| GOMF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 23/1243 | 135/23056 | 0.1703704 | 3.160144 | 6.008877 | 0.0000009 | 0.0000502 | 0.0000441 | RYR2/SLC8A1/ATP2B2/CACNA2D2/CACNA1D/CHRNA9/CNR1/OPRM1/SLC24A2/GRIN1/CACNA1B/SLC8A3/CHRNA7/CACNG5/CACNG4/CACNG1/SLC8A2/CACNG7/TMC2/CACNG2/PKDREJ/CACNA1F/ATP2B3 | 23 |
| GOBP_FEEDING_BEHAVIOR | GOBP_FEEDING_BEHAVIOR | GOBP_FEEDING_BEHAVIOR | 20/1243 | 107/23056 | 0.1869159 | 3.467042 | 6.105861 | 0.0000010 | 0.0000567 | 0.0000498 | OPRD1/HCRTR1/SGIP1/CNTN2/HAND2/MRAP2/CNR1/FYN/OPRM1/NPY/NTRK2/PRLHR/TH/GAL/DRD2/ATP8A2/DACH1/PPY/ACE/MC4R | 20 |
| GOBP_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 39/1243 | 313/23056 | 0.1246006 | 2.311177 | 5.575321 | 0.0000010 | 0.0000572 | 0.0000502 | NPPA/HPCA/PDE4B/ATP1B1/RYR2/SLC8A1/ATP2B2/CACNA2D2/CACNA1D/CHRNA9/ANK2/FYN/OPRM1/SLC24A2/GRIN1/CACNA1B/ADRA2A/DRD2/NOS1/P2RX7/JPH4/AKAP6/HSPA2/SLC8A3/CALM1/CHRNA7/JPH3/CACNG5/CACNG4/CACNG1/JSRP1/SLC8A2/HRC/CACNG7/TMC2/CACNG2/PKDREJ/CACNA1F/ATP2B3 | 39 |
| GOBP_MUSCLE_SYSTEM_PROCESS | GOBP_MUSCLE_SYSTEM_PROCESS | GOBP_MUSCLE_SYSTEM_PROCESS | 50/1243 | 449/23056 | 0.1113586 | 2.065554 | 5.442989 | 0.0000010 | 0.0000572 | 0.0000502 | NPPA/PDE4B/PTGER3/CHRNB2/ATP1B1/ADORA1/RYR2/CHRM3/SLC8A1/CXCR4/SCN1A/SCN7A/CHRNA1/CHRND/GRIP2/SCN5A/CACNA1D/PROK2/KLF15/FGF12/KIT/ANK2/GUCY1A1/HAND2/CLCN1/KCNB2/TMOD1/MYMK/ADRA2A/P2RX3/DRD2/SCN4B/SCN3B/KCNJ8/NOS1/ATP8A2/AKAP6/SLC8A3/CALM1/CHGA/CHRNA3/CHRNB4/ABAT/SSTR2/PVALEF/DSC2/JSRP1/HRC/SULF2/EDN3 | 50 |
| GOBP_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_LONG_TERM_SYNAPTIC_POTENTIATION | 19/1243 | 98/23056 | 0.1938776 | 3.596171 | 6.148084 | 0.0000010 | 0.0000581 | 0.0000510 | PRKCZ/TNR/ADORA1/IGSF11/NSG1/SCGN/RELN/CALB1/SLC24A2/NTRK2/SHANK2/DRD2/SLC8A3/CHRNA7/VAMP2/SLC8A2/PRKCG/SHISA7/SNAP25 | 19 |
| GOCC_SITE_OF_POLARIZED_GROWTH | GOCC_SITE_OF_POLARIZED_GROWTH | GOCC_SITE_OF_POLARIZED_GROWTH | 26/1243 | 167/23056 | 0.1556886 | 2.887817 | 5.844740 | 0.0000011 | 0.0000586 | 0.0000515 | ELAVL4/KIF5C/MAP2/CDK5R2/ERC2/GAP43/HCLS1/UNC5C/GPRIN1/GRM6/NRSN1/CNR1/STMN4/OLFM1/SHANK2/NECTIN1/ENO2/PTPRO/CDK5R1/MAPT/DCC/ATCAY/LAMP5/SNAP25/INPP5J/L1CAM | 26 |
| GOMF_GLUTAMATE_RECEPTOR_BINDING | GOMF_GLUTAMATE_RECEPTOR_BINDING | GOMF_GLUTAMATE_RECEPTOR_BINDING | 12/1243 | 41/23056 | 0.2926829 | 5.428880 | 6.775491 | 0.0000011 | 0.0000586 | 0.0000515 | ATP2B2/GRIP2/IGSF11/FYN/SHANK2/DRD2/CDK5R1/CACNG4/SHANK1/SHISA7/SYNDIG1/CACNG2 | 12 |
| GOBP_NEURON_CELL_CELL_ADHESION | GOBP_NEURON_CELL_CELL_ADHESION | GOBP_NEURON_CELL_CELL_ADHESION | 8/1243 | 17/23056 | 0.4705882 | 8.728787 | 7.609645 | 0.0000011 | 0.0000608 | 0.0000534 | TNR/NRXN1/CNTN4/NRXN2/NRXN3/CDK5R1/NLGN3/NLGN4Y | 8 |
| REACTOME_NEUREXINS_AND_NEUROLIGINS | REACTOME_NEUREXINS_AND_NEUROLIGINS | REACTOME_NEUREXINS_AND_NEUROLIGINS | 14/1243 | 56/23056 | 0.2500000 | 4.637168 | 6.505099 | 0.0000011 | 0.0000620 | 0.0000544 | DLGAP3/NRXN1/DLGAP2/STXBP1/GRIN1/SYT7/NRXN2/SHANK2/GRM5/NRXN3/BEGAIN/SHANK1/NLGN3/NLGN4Y | 14 |
| LEE_NEURAL_CREST_STEM_CELL_UP | LEE_NEURAL_CREST_STEM_CELL_UP | LEE_NEURAL_CREST_STEM_CELL_UP | 24/1243 | 147/23056 | 0.1632653 | 3.028355 | 5.889249 | 0.0000011 | 0.0000622 | 0.0000547 | CELF3/NFASC/NRXN1/SCN3A/TAGLN3/GAP43/RBP1/BCHE/PDGFRA/SERPINB9/TFAP2B/CNR1/LZTS1/STMN4/SORBS1/SLIT1/INA/PCDH8/CHGA/SCG3/CRABP1/SNAP25/DCX/L1CAM | 24 |
| REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | 19/1243 | 99/23056 | 0.1919192 | 3.559846 | 6.093044 | 0.0000012 | 0.0000664 | 0.0000584 | SOX11/CHRND/ARPP21/CACNA2D2/TUBB2B/TFAP2B/CNR1/EYA1/TMOD1/CELF2/CDKN1C/PDE2A/SCN3B/PCDH17/ZNF536/RTN2/PPP1R16B/EYA2/DCX | 19 |
| GOCC_MEMBRANE_MICRODOMAIN | GOCC_MEMBRANE_MICRODOMAIN | GOCC_MEMBRANE_MICRODOMAIN | 40/1243 | 329/23056 | 0.1215805 | 2.255158 | 5.473758 | 0.0000014 | 0.0000753 | 0.0000662 | PRKCZ/OPRD1/KCNA3/CHRNB2/ATP1B1/TNR/RGS7/ADD2/CD8A/ATP2B2/SCN5A/ANK2/TLR2/UNC5A/CNR1/CD24/FYN/OPRM1/DLL1/ADCYAP1R1/ABCB4/CAVIN4/SORBS1/SLC1A2/P2RX3/SLC22A6/ENO2/CNTN1/FAIM2/NOS1/AKAP6/CHRNA7/CLN6/CHRNA3/SLC6A2/RTN4RL1/MAPT/RIT2/ITGB2/GPM6B | 40 |
| HP_NON_MOTOR_SEIZURE | HP_NON_MOTOR_SEIZURE | HP_NON_MOTOR_SEIZURE | 28/1243 | 191/23056 | 0.1465969 | 2.719177 | 5.695241 | 0.0000014 | 0.0000770 | 0.0000677 | GABRD/CNTN2/MYT1L/SCN1A/KIF1A/SLC6A1/SATB1/ADGRV1/GABRG2/DLL1/RELN/KCNQ3/STXBP1/GRIN1/BRSK2/GAL/PDE2A/CUX2/GABRB3/STX1B/TCF4/CACNG2/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/RAB39B | 28 |
| GOBP_DENDRITE_MORPHOGENESIS | GOBP_DENDRITE_MORPHOGENESIS | GOBP_DENDRITE_MORPHOGENESIS | 23/1243 | 139/23056 | 0.1654676 | 3.069205 | 5.841070 | 0.0000015 | 0.0000800 | 0.0000703 | ELAVL4/CHRNB2/CTNNA2/KLF7/MAP2/KIF1A/CTNND2/PHACTR1/DCDC2/ADGRB3/FYN/RELN/LZTS1/MAP6/CUX2/CHRNA7/CHRNA3/CDK5R1/SRCIN1/SHANK1/MAPK8IP2/ZDHHC15/PAK3 | 23 |
| GOBP_MULTICELLULAR_ORGANISMAL_RESPONSE_TO_STRESS | GOBP_MULTICELLULAR_ORGANISMAL_RESPONSE_TO_STRESS | GOBP_MULTICELLULAR_ORGANISMAL_RESPONSE_TO_STRESS | 16/1243 | 74/23056 | 0.2162162 | 4.010524 | 6.191907 | 0.0000016 | 0.0000863 | 0.0000759 | NTRK1/ASIC4/GRIK2/ADCYAP1R1/RELN/BRINP1/DBH/ADRA2A/P2RX3/NOS1/GCH1/GABRA5/SLC6A2/BCL2/PRKCG/MAPK8IP2 | 16 |
| GOBP_POSITIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | GOBP_POSITIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | GOBP_POSITIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY | 13/1243 | 50/23056 | 0.2600000 | 4.822655 | 6.459367 | 0.0000017 | 0.0000889 | 0.0000782 | CDK5R2/GATA2/CNR1/SYK/STXBP1/SYT7/SLC4A8/SCAMP5/DOC2B/SYT4/RAB3A/ITGB2/PLA2G3 | 13 |
| GOBP_NEGATIVE_REGULATION_OF_CATECHOLAMINE_SECRETION | GOBP_NEGATIVE_REGULATION_OF_CATECHOLAMINE_SECRETION | GOBP_NEGATIVE_REGULATION_OF_CATECHOLAMINE_SECRETION | 7/1243 | 13/23056 | 0.5384615 | 9.987747 | 7.737727 | 0.0000017 | 0.0000889 | 0.0000782 | SYT11/CNR1/ADRA2A/DRD2/CHGA/ABAT/SYT4 | 7 |
| GOCC_NEURONAL_DENSE_CORE_VESICLE | GOCC_NEURONAL_DENSE_CORE_VESICLE | GOCC_NEURONAL_DENSE_CORE_VESICLE | 7/1243 | 13/23056 | 0.5384615 | 9.987747 | 7.737727 | 0.0000017 | 0.0000889 | 0.0000782 | OPRD1/KIF1A/CADPS/NPY/CHGA/SYT4/SYT5 | 7 |
| GOBP_CATECHOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | GOBP_CATECHOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | GOBP_CATECHOL_CONTAINING_COMPOUND_METABOLIC_PROCESS | 14/1243 | 58/23056 | 0.2413793 | 4.477266 | 6.329469 | 0.0000018 | 0.0000936 | 0.0000823 | CHRNB2/HAND2/SNCB/NPY/DDC/DBH/TH/DRD2/PAH/KL/GCH1/ABAT/ITGB2/MAOB | 14 |
| REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | 12/1243 | 43/23056 | 0.2790698 | 5.176374 | 6.543459 | 0.0000018 | 0.0000971 | 0.0000854 | KCNA3/KCNH1/KCNH7/KCNH8/KCNB2/KCNQ3/KCNC1/KCNC2/KCNH5/KCNH4/KCNH6/KCNC3 | 12 |
| REACTOME_METABOLISM_OF_AMINE_DERIVED_HORMONES | REACTOME_METABOLISM_OF_AMINE_DERIVED_HORMONES | REACTOME_METABOLISM_OF_AMINE_DERIVED_HORMONES | 8/1243 | 18/23056 | 0.4444444 | 8.243854 | 7.339120 | 0.0000019 | 0.0000980 | 0.0000861 | TPO/DDC/DBH/TH/TPH2/DIO3/DUOX1/ASMT | 8 |
| REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE | REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE | 8/1243 | 18/23056 | 0.4444444 | 8.243854 | 7.339120 | 0.0000019 | 0.0000980 | 0.0000861 | PPFIA4/CPLX1/RIMS1/STXBP1/VAMP2/RAB3A/PPFIA3/SNAP25 | 8 |
| HP_FOCAL_ONSET_SEIZURE | HP_FOCAL_ONSET_SEIZURE | HP_FOCAL_ONSET_SEIZURE | 38/1243 | 309/23056 | 0.1229773 | 2.281067 | 5.411894 | 0.0000019 | 0.0000991 | 0.0000871 | GABRD/CHRNB2/CNTN2/MYT1L/DPYSL5/SCN1A/KIF1A/SLC6A1/SATB1/CACNA1D/CPLX1/CTNND2/ADGRV1/GABRG2/TUBB2B/GRIK2/DLL1/RELN/CNTNAP2/CHRNA2/KCNQ3/STXBP1/GRIN1/BRSK2/KCNJ11/GAL/PDE2A/CUX2/GABRB3/GABRA5/STX1B/VAMP2/TCF4/ATP1A3/CACNG2/SYN1/NEXMIF/DCX | 38 |
| GOBP_POSTSYNAPSE_ORGANIZATION | GOBP_POSTSYNAPSE_ORGANIZATION | GOBP_POSTSYNAPSE_ORGANIZATION | 25/1243 | 162/23056 | 0.1543210 | 2.862449 | 5.678604 | 0.0000020 | 0.0001027 | 0.0000902 | NRXN1/KIF1A/LHFPL4/GAP43/TMEM108/SLITRK3/CTNND2/LRFN2/FYN/RELN/INA/NRXN2/SHANK2/CUX2/CHRNA7/CBLN1/CDK5R1/SRCIN1/SHANK1/SHISA7/NEFH/NLGN3/ZDHHC15/PAK3/NLGN4Y | 25 |
| GOCC_PHOTORECEPTOR_OUTER_SEGMENT | GOCC_PHOTORECEPTOR_OUTER_SEGMENT | GOCC_PHOTORECEPTOR_OUTER_SEGMENT | 18/1243 | 93/23056 | 0.1935484 | 3.590066 | 5.974456 | 0.0000020 | 0.0001041 | 0.0000915 | ABCA4/RD3/PCARE/MYRIP/PDE6B/PROM1/GUCA1A/RP1L1/CDHR1/OPN4/USH1C/SHANK2/ATP8A2/GRK1/CNGB1/GUCY2D/PRCD/CACNA1F | 18 |
| GOBP_MEMBRANE_DEPOLARIZATION | GOBP_MEMBRANE_DEPOLARIZATION | GOBP_MEMBRANE_DEPOLARIZATION | 17/1243 | 84/23056 | 0.2023810 | 3.753898 | 6.035990 | 0.0000020 | 0.0001041 | 0.0000915 | PRKCZ/CHRNB2/HCN3/SLC8A1/SCN3A/SCN1A/SCN7A/SCN5A/CACNA1D/CHRNA9/ANK2/SCN4B/SCN3B/P2RX7/CNGB1/BCL2/CACNG2 | 17 |
| GOBP_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | GOBP_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | GOBP_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | 36/1243 | 286/23056 | 0.1258741 | 2.334798 | 5.422224 | 0.0000020 | 0.0001042 | 0.0000916 | ABCA4/AQP10/CHRNB2/SYT11/APOB/OSBPL6/ABCA12/GRM2/AGTR1/SLC10A4/CNR1/VIP/ABCB4/SLC18A1/SYK/ADRA2A/SYT8/SYT13/SYT7/SLC22A24/GAL/FGF19/DRD2/SLCO1B1/NOS1/CHGA/ABAT/SLC6A2/SYT4/RAB3A/SYT3/SYT5/HRH3/ABCG1/GPM6B/MAOB | 36 |
| SHEN_SMARCA2_TARGETS_DN | SHEN_SMARCA2_TARGETS_DN | SHEN_SMARCA2_TARGETS_DN | 39/1243 | 322/23056 | 0.1211180 | 2.246578 | 5.377371 | 0.0000020 | 0.0001042 | 0.0000916 | GABRD/NPPA/ACTL8/HTR6/TNR/CNTN2/ALLC/ADD2/CRYGB/ASIC4/CHRND/CAMKV/NPY2R/GABRG2/GLP1R/GABRR2/OPRM1/CLCN1/LZTS1/SLC24A2/PAX5/USH1C/SLC1A2/DRD2/NECTIN1/GPR12/KCNK10/GJD2/CHRNA3/CDK5R1/RUNDC3A/EPX/POU2F2/BMP7/MYT1/TMPRSS15/ARSF/SSX3/XPNPEP2 | 39 |
| GOCC_T_TUBULE | GOCC_T_TUBULE | GOCC_T_TUBULE | 13/1243 | 51/23056 | 0.2549020 | 4.728093 | 6.362402 | 0.0000021 | 0.0001080 | 0.0000949 | ATP1B1/SLC8A1/DYSF/SCN1A/SCN5A/CACNA1D/ANK2/KCNJ11/AKAP6/CACNG4/CACNG1/RTN2/CACNG7 | 13 |
| GOBP_REGULATION_OF_SYNAPSE_ASSEMBLY | GOBP_REGULATION_OF_SYNAPSE_ASSEMBLY | GOBP_REGULATION_OF_SYNAPSE_ASSEMBLY | 19/1243 | 103/23056 | 0.1844660 | 3.421600 | 5.879788 | 0.0000023 | 0.0001138 | 0.0001000 | CHRNB2/NTRK1/NRXN1/LHFPL4/CLSTN2/SLITRK3/TLR2/ADGRB3/NTRK2/SLIT1/VSTM5/NECTIN1/CUX2/SLITRK1/SLITRK5/ST8SIA2/CBLN1/SYNDIG1/NLGN3 | 19 |
| HP_STEREOTYPY | HP_STEREOTYPY | HP_STEREOTYPY | 33/1243 | 252/23056 | 0.1309524 | 2.428993 | 5.444841 | 0.0000023 | 0.0001138 | 0.0001000 | GABRD/PRKCZ/NTNG1/CHRNB2/MYT1L/DPYSL5/KIF5C/SCN1A/KIF1A/SATB1/CPLX1/GABRG2/GRIK2/DLL1/DDC/CNTNAP2/CHRNA2/NTRK2/STXBP1/GRIN1/BRSK2/PDE2A/GABRB3/GUCY2D/VAMP2/MAPT/ASXL3/TCF4/NOVA2/CACNG2/NLGN3/NEXMIF/RAB39B | 33 |
| GOBP_NEUROTRANSMITTER_RECEPTOR_TRANSPORT | GOBP_NEUROTRANSMITTER_RECEPTOR_TRANSPORT | GOBP_NEUROTRANSMITTER_RECEPTOR_TRANSPORT | 9/1243 | 24/23056 | 0.3750000 | 6.955752 | 6.968460 | 0.0000023 | 0.0001170 | 0.0001028 | GRIP2/CPLX1/NSG1/STX1B/CACNG5/CACNG4/CACNG7/SNAP25/CACNG2 | 9 |
| GOBP_REGULATION_OF_NEUROGENESIS | GOBP_REGULATION_OF_NEUROGENESIS | GOBP_REGULATION_OF_NEUROGENESIS | 42/1243 | 361/23056 | 0.1163435 | 2.158017 | 5.293757 | 0.0000024 | 0.0001198 | 0.0001053 | NGF/TNR/SOX11/CXCR4/MAP2/HES6/SEMA5B/FAIM/KIT/POU4F2/TLR2/FSTL4/TTBK1/OPRM1/DLL1/FERD3L/RELN/NTRK2/BRINP1/SLIT1/NEURL1/RASSF10/MAP6/GRM5/DRD2/ASCL1/CUX2/SLITRK1/SPINT1/ISLR2/RNF112/CDK5R1/MAPT/ACE/SYT4/DCC/DLL3/BMP7/CHODL/TIAM1/PAK3/L1CAM | 42 |
| WANG_LSD1_TARGETS_DN | WANG_LSD1_TARGETS_DN | WANG_LSD1_TARGETS_DN | 11/1243 | 37/23056 | 0.2972973 | 5.514470 | 6.560318 | 0.0000025 | 0.0001238 | 0.0001088 | RIMS3/SYN2/CPLX2/STXBP1/CHGA/SYT4/CHST8/DLL3/CHGB/SNAP25/PCSK1N | 11 |
| GOBP_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | GOBP_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | GOBP_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | 13/1243 | 52/23056 | 0.2500000 | 4.637168 | 6.267925 | 0.0000027 | 0.0001335 | 0.0001174 | GRIK3/GRM2/GRM6/GRM4/GRIK2/FYN/GRM8/GRIN1/GRM5/GRIA4/GRIK4/CDK5R1/GRIA3 | 13 |
| GOBP_DENDRITE_DEVELOPMENT | GOBP_DENDRITE_DEVELOPMENT | GOBP_DENDRITE_DEVELOPMENT | 31/1243 | 231/23056 | 0.1341991 | 2.489216 | 5.430235 | 0.0000027 | 0.0001337 | 0.0001175 | ELAVL4/CHRNB2/ALK/BCL11A/CTNNA2/KLF7/MAP2/KIF1A/CTNND2/FSTL4/PHACTR1/DCDC2/PACSIN1/ADGRB3/FYN/ACTL6B/RELN/LZTS1/NEURL1/MAP6/CUX2/CHRNA7/CHRNA3/CDK5R1/SRCIN1/DCC/SHANK1/BMP7/MAPK8IP2/ZDHHC15/PAK3 | 31 |
| GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING | GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING | GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING | 37/1243 | 302/23056 | 0.1225166 | 2.272520 | 5.313730 | 0.0000028 | 0.0001389 | 0.0001220 | NPPA/HPCA/ATP1B1/RYR2/CHRM3/SLC8A1/CXCR4/AGTR1/ANK2/GUCY1A1/GLP1R/GUCA1A/ADCYAP1R1/DEFB1/DMTN/SYK/GRIN1/C10orf71/P2RX3/GAL/PDE2A/GRM5/KCNC2/NOS1/KSR2/P2RX7/AKAP6/CALM1/MCTP2/GUCY2D/RUNDC3A/MAPT/RIT2/P2RY11/SLC8A2/HRC/EDN3 | 37 |
| GOBP_IMPORT_INTO_CELL | GOBP_IMPORT_INTO_CELL | GOBP_IMPORT_INTO_CELL | 31/1243 | 232/23056 | 0.1336207 | 2.478486 | 5.402887 | 0.0000030 | 0.0001453 | 0.0001277 | PLPPR4/KCNJ9/ATP1B1/SLC8A1/SLC6A11/SLC6A1/ACSL1/FYN/TFR2/SLC18A1/KCNK9/SLC24A2/KCNJ11/SLC6A5/SLC1A2/DRD2/IL10RA/KCNJ8/NOS1/IRS2/SLC8A3/SLC27A2/SLC6A2/SLC1A6/ATP4A/ATP1A3/SLC8A2/SNAP25/KCNJ6/GPM6B/SLC7A3 | 31 |
| GOCC_INHIBITORY_SYNAPSE | GOCC_INHIBITORY_SYNAPSE | GOCC_INHIBITORY_SYNAPSE | 8/1243 | 19/23056 | 0.4210526 | 7.809967 | 7.088744 | 0.0000031 | 0.0001503 | 0.0001320 | IGSF21/SYT11/LHFPL4/GABRG2/IQSEC3/SLC32A1/NLGN3/NLGN4Y | 8 |
| GOMF_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY | 12/1243 | 45/23056 | 0.2666667 | 4.946313 | 6.325436 | 0.0000031 | 0.0001516 | 0.0001332 | CACNA2D2/CACNA1D/CNR1/OPRM1/CACNA1B/CACNG5/CACNG4/CACNG1/CACNG7/TMC2/CACNG2/CACNA1F | 12 |
| GOBP_SYNAPTIC_VESICLE_CLUSTERING | GOBP_SYNAPTIC_VESICLE_CLUSTERING | GOBP_SYNAPTIC_VESICLE_CLUSTERING | 7/1243 | 14/23056 | 0.5000000 | 9.274336 | 7.392605 | 0.0000032 | 0.0001541 | 0.0001354 | SYN2/BRSK2/PCDH17/RAB3A/BRSK1/SYNDIG1/SYN1 | 7 |
| GOBP_SODIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_SODIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_SODIUM_ION_TRANSMEMBRANE_TRANSPORT | 26/1243 | 177/23056 | 0.1468927 | 2.724664 | 5.498358 | 0.0000032 | 0.0001541 | 0.0001354 | SLC6A17/HCN3/ATP1B1/SLC8A1/SCN3A/SCN1A/SCN7A/ASIC4/SLC6A11/SLC6A1/SCN5A/FGF12/SLC24A2/SLC6A5/SCN4B/SCN3B/SLC4A8/SLC6A15/NOS1/FGF14/SLC8A3/SLC6A2/FGF11/ATP4A/ATP1A3/SLC8A2 | 26 |
| GOBP_REGULATION_OF_HORMONE_SECRETION | GOBP_REGULATION_OF_HORMONE_SECRETION | GOBP_REGULATION_OF_HORMONE_SECRETION | 31/1243 | 234/23056 | 0.1324786 | 2.457303 | 5.348615 | 0.0000036 | 0.0001694 | 0.0001489 | ADORA1/SOX11/VSNL1/KLF7/ABCA12/MYRIP/GPR27/ADCY5/AGTR1/ISL1/SOX4/GPLD1/TFAP2B/CNR1/RFX6/ICA1/TFR2/ADRA2A/BRSK2/KCNJ11/SYT7/GAL/DRD2/IRS2/CHGA/ABAT/DOC2B/VAMP2/SNAP25/EDN3/PLA2G3 | 31 |
| GOBP_STRIATED_MUSCLE_CONTRACTION | GOBP_STRIATED_MUSCLE_CONTRACTION | GOBP_STRIATED_MUSCLE_CONTRACTION | 26/1243 | 178/23056 | 0.1460674 | 2.709357 | 5.465049 | 0.0000036 | 0.0001694 | 0.0001489 | NPPA/PDE4B/ATP1B1/ADORA1/RYR2/SLC8A1/CXCR4/SCN1A/CHRNA1/CHRND/SCN5A/CACNA1D/FGF12/ANK2/SCN4B/SCN3B/KCNJ8/NOS1/ATP8A2/SLC8A3/CALM1/CHGA/PVALEF/DSC2/JSRP1/HRC | 26 |
| KEGG_CALCIUM_SIGNALING_PATHWAY | KEGG_CALCIUM_SIGNALING_PATHWAY | KEGG_CALCIUM_SIGNALING_PATHWAY | 26/1243 | 178/23056 | 0.1460674 | 2.709357 | 5.465049 | 0.0000036 | 0.0001694 | 0.0001489 | HTR6/PTGER3/RYR2/CHRM3/SLC8A1/PDE1A/PLCD4/ATP2B2/CACNA1D/AGTR1/PDGFRA/HRH2/GRIN1/CACNA1B/P2RX3/CHRM1/GRM5/NOS1/P2RX7/SLC8A3/CALM1/CHRNA7/SLC8A2/PRKCG/CACNA1F/ATP2B3 | 26 |
| GOBP_RESPONSE_TO_ALKALOID | GOBP_RESPONSE_TO_ALKALOID | GOBP_RESPONSE_TO_ALKALOID | 18/1243 | 97/23056 | 0.1855670 | 3.442022 | 5.753331 | 0.0000038 | 0.0001799 | 0.0001581 | ELAVL4/CHRNB2/RYR2/SLC8A1/CXCR4/SLC6A1/GRM2/BCHE/CNR1/OPRM1/DDC/TH/SLC1A2/DRD2/ST8SIA2/ABAT/CACNG4/PRKCG | 18 |
| GOBP_REGULATION_OF_INSULIN_SECRETION | GOBP_REGULATION_OF_INSULIN_SECRETION | GOBP_REGULATION_OF_INSULIN_SECRETION | 23/1243 | 147/23056 | 0.1564626 | 2.902173 | 5.522886 | 0.0000040 | 0.0001869 | 0.0001642 | VSNL1/KLF7/ABCA12/MYRIP/GPR27/ADCY5/ISL1/SOX4/GPLD1/TFAP2B/CNR1/RFX6/ICA1/ADRA2A/BRSK2/KCNJ11/SYT7/DRD2/IRS2/CHGA/ABAT/DOC2B/SNAP25 | 23 |
| REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | 39/1243 | 331/23056 | 0.1178248 | 2.185493 | 5.185869 | 0.0000040 | 0.0001885 | 0.0001657 | HTR6/OPRD1/HCRTR1/PTGER3/PLPPR5/PLPPR4/ACKR1/ADORA1/CHRM3/OXER1/PROKR1/CXCR4/PROK2/AGTR1/ECE2/KNG1/NPY2R/HRH2/HTR1E/CNR1/OPRM1/NPY/RLN2/PLPPR1/OPN4/ADRA2A/PRLHR/CHRM1/GAL/DRD2/TAC3/PPY/SSTR2/MC4R/PLPPR3/P2RY11/PROKR2/EDN3/HRH3 | 39 |
| MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | 34/1243 | 271/23056 | 0.1254613 | 2.327140 | 5.246108 | 0.0000042 | 0.0001961 | 0.0001723 | PAX7/BMP8B/IRF6/HOXD8/HOXD1/FEV/ECEL1/POU4F2/HAND2/GFRA3/HAND1/GLP1R/NPY/WDR86/FGF17/IGFBPL1/DRGX/CHAT/ADAMTS14/GAL/HOXC4/FOXN4/INSM2/GSC/DLK1/DIO3/SPINT1/CHRNA3/RHCG/IRX6/SLC6A2/RSPO4/KCNK15/SALL4 | 34 |
| GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTRASPECIES_INTERACTION_BETWEEN_ORGANISMS | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTRASPECIES_INTERACTION_BETWEEN_ORGANISMS | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTRASPECIES_INTERACTION_BETWEEN_ORGANISMS | 13/1243 | 54/23056 | 0.2407407 | 4.465421 | 6.085980 | 0.0000043 | 0.0001979 | 0.0001739 | CHRNB2/NRXN1/CNTNAP2/BRINP1/TH/NRXN2/SHANK2/NRXN3/SHANK1/SEPTIN5/MAPK8IP2/NLGN3/NLGN4Y | 13 |
| GOMF_CELL_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_CELL_ADHESION_MEDIATOR_ACTIVITY | 13/1243 | 54/23056 | 0.2407407 | 4.465421 | 6.085980 | 0.0000043 | 0.0001979 | 0.0001739 | NTNG1/NFASC/CNTN2/CNTN6/CNTN4/CD200/LRRC4C/DSCAML1/TRIM29/CNTN1/STXBP6/DSC2/VSTM2L | 13 |
| GOBP_NEUROPEPTIDE_SIGNALING_PATHWAY | GOBP_NEUROPEPTIDE_SIGNALING_PATHWAY | GOBP_NEUROPEPTIDE_SIGNALING_PATHWAY | 19/1243 | 108/23056 | 0.1759259 | 3.263192 | 5.627576 | 0.0000047 | 0.0002175 | 0.0001911 | NPPA/OPRD1/HCRTR1/PROKR1/ECEL1/PROK2/NPY2R/GLRA3/OPRM1/NPY/SORCS3/PRLHR/GAL/TAC3/GPR139/PPY/SSTR2/PROKR2/PCSK1N | 19 |
| GOBP_SODIUM_ION_TRANSPORT | GOBP_SODIUM_ION_TRANSPORT | GOBP_SODIUM_ION_TRANSPORT | 32/1243 | 249/23056 | 0.1285141 | 2.383765 | 5.240689 | 0.0000048 | 0.0002208 | 0.0001941 | SLC6A17/HCN3/ATP1B1/SLC8A1/SCN3A/SCN1A/SCN7A/ASIC4/SLC6A11/SLC6A1/SCN5A/SLC38A3/FGF12/SLC10A4/SLC24A2/SLC6A5/DRD2/SCN4B/SCN3B/CNTN1/SLC4A8/SLC6A15/SLC17A8/NOS1/P2RX7/FGF14/SLC8A3/SLC6A2/FGF11/ATP4A/ATP1A3/SLC8A2 | 32 |
| GOBP_REGULATION_OF_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_MUSCLE_CONTRACTION | 25/1243 | 170/23056 | 0.1470588 | 2.727746 | 5.397341 | 0.0000048 | 0.0002213 | 0.0001945 | NPPA/PDE4B/ATP1B1/ADORA1/RYR2/CHRM3/SLC8A1/SCN5A/PROK2/KIT/ANK2/GUCY1A1/KCNB2/ADRA2A/NOS1/SLC8A3/CALM1/CHGA/CHRNA3/CHRNB4/ABAT/SSTR2/PVALEF/DSC2/HRC | 25 |
| GOCC_AMPA_GLUTAMATE_RECEPTOR_COMPLEX | GOCC_AMPA_GLUTAMATE_RECEPTOR_COMPLEX | GOCC_AMPA_GLUTAMATE_RECEPTOR_COMPLEX | 9/1243 | 26/23056 | 0.3461538 | 6.420694 | 6.601689 | 0.0000051 | 0.0002300 | 0.0002021 | OLFM3/CNIH2/GRIA4/CACNG5/CACNG4/CACNG7/SHISA7/CACNG2/GRIA3 | 9 |
| GOCC_SODIUM_CHANNEL_COMPLEX | GOCC_SODIUM_CHANNEL_COMPLEX | GOCC_SODIUM_CHANNEL_COMPLEX | 9/1243 | 26/23056 | 0.3461538 | 6.420694 | 6.601689 | 0.0000051 | 0.0002300 | 0.0002021 | GRIK3/SCN3A/SCN1A/SCN7A/SCN5A/GRIK2/SCN4B/GRIK4/SCN3B | 9 |
| GOCC_PHOTORECEPTOR_INNER_SEGMENT | GOCC_PHOTORECEPTOR_INNER_SEGMENT | GOCC_PHOTORECEPTOR_INNER_SEGMENT | 14/1243 | 63/23056 | 0.2222222 | 4.121927 | 5.923190 | 0.0000051 | 0.0002300 | 0.0002021 | RD3/PCARE/ADGRV1/GUCA1A/SLC24A2/CDH23/USH1C/SHANK2/ENO2/NOS1/ATP8A2/ATP1A3/SNAP25/RS1 | 14 |
| GOBP_CARDIAC_CONDUCTION | GOBP_CARDIAC_CONDUCTION | GOBP_CARDIAC_CONDUCTION | 18/1243 | 99/23056 | 0.1818182 | 3.372486 | 5.647082 | 0.0000051 | 0.0002323 | 0.0002042 | ATP1B1/RYR2/SLC8A1/ATP2B2/SCN5A/CACNA1D/ANK2/ISL1/SCN4B/SCN3B/SLC8A3/CALM1/KCNH6/DSC2/ATP1A3/SLC8A2/HRC/ATP2B3 | 18 |
| GOMF_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY | GOMF_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY | GOMF_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY | 17/1243 | 90/23056 | 0.1888889 | 3.503638 | 5.680814 | 0.0000055 | 0.0002462 | 0.0002163 | PLCH2/PDE4B/CHRM3/PDE1A/PLCD4/PLCL2/PDE6B/ENPP6/PLCXD3/GPLD1/ENPP2/MPPED2/CHRM1/PDE2A/GDPD4/PLD4/SMPD3 | 17 |
| BLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_DN | BLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_DN | BLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_DN | 20/1243 | 119/23056 | 0.1680672 | 3.117424 | 5.528069 | 0.0000055 | 0.0002470 | 0.0002171 | RAP1GAP/VWA5B2/CPLX2/CRIP3/DDC/SCARA5/AMBP/MUC5B/KCNJ11/USH1C/RERG/KSR2/DEGS2/CKMT1B/DOK4/RTN4RL1/CACNG4/PRR36/CCER2/CCN5 | 20 |
| GOBP_AMINO_ACID_TRANSPORT | GOBP_AMINO_ACID_TRANSPORT | GOBP_AMINO_ACID_TRANSPORT | 23/1243 | 150/23056 | 0.1533333 | 2.844130 | 5.409074 | 0.0000056 | 0.0002511 | 0.0002207 | SLC6A17/ADORA1/SLC6A11/SLC6A1/SLC38A3/GRM2/SLC25A48/SLC16A10/NTRK2/STXBP1/SLC6A5/SLC1A2/SLC6A15/SLC17A8/P2RX7/SLC25A29/ABAT/SYT4/SLC1A6/SLC32A1/HRH3/SLC38A5/SLC7A3 | 23 |
| GOBP_REGULATION_OF_SHORT_TERM_NEURONAL_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_SHORT_TERM_NEURONAL_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_SHORT_TERM_NEURONAL_SYNAPTIC_PLASTICITY | 7/1243 | 15/23056 | 0.4666667 | 8.656047 | 7.080436 | 0.0000057 | 0.0002543 | 0.0002234 | GRIK2/SYT4/RAB3A/SLC8A2/PPFIA3/SHISA7/SYP | 7 |
| GOBP_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION | GOBP_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION | GOBP_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION | 10/1243 | 33/23056 | 0.3030303 | 5.620810 | 6.340953 | 0.0000059 | 0.0002608 | 0.0002292 | NTRK1/CXCR4/SCN1A/CHRNA9/KIT/ADGRV1/LHFPL5/FYN/STRC/TMC2 | 10 |
| GOBP_NEURON_CELLULAR_HOMEOSTASIS | GOBP_NEURON_CELLULAR_HOMEOSTASIS | GOBP_NEURON_CELLULAR_HOMEOSTASIS | 10/1243 | 33/23056 | 0.3030303 | 5.620810 | 6.340953 | 0.0000059 | 0.0002608 | 0.0002292 | ADORA1/HAAO/CHRNA1/ATP2B2/SCGN/CNR1/CALB1/SLC6A2/SLC8A2/ATP2B3 | 10 |
| GOCC_GLIAL_CELL_PROJECTION | GOCC_GLIAL_CELL_PROJECTION | GOCC_GLIAL_CELL_PROJECTION | 10/1243 | 33/23056 | 0.3030303 | 5.620810 | 6.340953 | 0.0000059 | 0.0002608 | 0.0002292 | NFASC/SCN7A/GRM2/FYN/SLC1A2/GRM5/SLC4A8/SLC17A8/MAPT/SYT4 | 10 |
| HP_TONIC_SEIZURE | HP_TONIC_SEIZURE | HP_TONIC_SEIZURE | 18/1243 | 100/23056 | 0.1800000 | 3.338761 | 5.594975 | 0.0000060 | 0.0002614 | 0.0002298 | MYT1L/SCN1A/KIF1A/SATB1/ADGRV1/GABRG2/PHACTR1/DLL1/KCNQ3/STXBP1/GRIN1/BRSK2/CUX2/GABRB3/GABRA5/TCF4/CACNG2/NEXMIF | 18 |
| GOMF_SNARE_BINDING | GOMF_SNARE_BINDING | GOMF_SNARE_BINDING | 19/1243 | 110/23056 | 0.1727273 | 3.203862 | 5.530795 | 0.0000062 | 0.0002719 | 0.0002390 | SYT11/STXBP5L/CPLX1/CPLX2/SNAP91/STXBP1/SYT8/SYT13/SYT7/CPLX3/STX1B/EXOC3L1/DOC2B/VAMP2/SYT4/UNC13A/SYT3/SYT5/SNAP25 | 19 |
| GOBP_NEUROMUSCULAR_PROCESS | GOBP_NEUROMUSCULAR_PROCESS | GOBP_NEUROMUSCULAR_PROCESS | 23/1243 | 152/23056 | 0.1513158 | 2.806707 | 5.334753 | 0.0000071 | 0.0003070 | 0.0002698 | GPR88/TNR/NRXN1/CTNNA2/SCN1A/CHRNA1/CHRND/ADCY5/FGF12/POU4F2/CDH23/USH1C/DRD2/HOXC10/ASCL1/ATP8A2/JPH4/GCH1/SLC8A3/JPH3/PVALEF/JSRP1/SHANK1 | 23 |
| GOBP_NEGATIVE_REGULATION_OF_AMINE_TRANSPORT | GOBP_NEGATIVE_REGULATION_OF_AMINE_TRANSPORT | GOBP_NEGATIVE_REGULATION_OF_AMINE_TRANSPORT | 9/1243 | 27/23056 | 0.3333333 | 6.182891 | 6.432456 | 0.0000072 | 0.0003141 | 0.0002761 | SYT11/ADORA1/CNR1/ADRA2A/DRD2/CHGA/ABAT/SYT4/HRH3 | 9 |
| LEIN_PONS_MARKERS | LEIN_PONS_MARKERS | LEIN_PONS_MARKERS | 17/1243 | 92/23056 | 0.1847826 | 3.427472 | 5.569097 | 0.0000075 | 0.0003223 | 0.0002832 | HCRTR1/KANK4/ANKRD35/ESRRG/SGPP2/VWA5B2/ECE2/MRAP2/CDH23/SLC6A5/GPC5/DLK1/CHRNB4/RTN2/B3GALT5/S100B/PCSK1N | 17 |
| HP_FOCAL_NON_MOTOR_SEIZURE | HP_FOCAL_NON_MOTOR_SEIZURE | HP_FOCAL_NON_MOTOR_SEIZURE | 14/1243 | 65/23056 | 0.2153846 | 3.995099 | 5.772306 | 0.0000075 | 0.0003223 | 0.0002833 | CNTN2/MYT1L/SCN1A/KIF1A/DLL1/RELN/KCNQ3/STXBP1/GRIN1/BRSK2/GAL/PDE2A/TCF4/CACNG2 | 14 |
| GOBP_MAINTENANCE_OF_SYNAPSE_STRUCTURE | GOBP_MAINTENANCE_OF_SYNAPSE_STRUCTURE | GOBP_MAINTENANCE_OF_SYNAPSE_STRUCTURE | 8/1243 | 21/23056 | 0.3809524 | 7.066161 | 6.638805 | 0.0000076 | 0.0003224 | 0.0002833 | BSN/ERC2/ADGRB3/SHANK2/CBLN1/C1QL1/RAB3A/CBLN4 | 8 |
| GOCC_GABA_RECEPTOR_COMPLEX | GOCC_GABA_RECEPTOR_COMPLEX | GOCC_GABA_RECEPTOR_COMPLEX | 8/1243 | 21/23056 | 0.3809524 | 7.066161 | 6.638805 | 0.0000076 | 0.0003224 | 0.0002833 | GABRD/GABRG1/GABRG2/GABRP/GABRR2/GABRB3/GABRA5/GABRG3 | 8 |
| GOBP_CELL_JUNCTION_MAINTENANCE | GOBP_CELL_JUNCTION_MAINTENANCE | GOBP_CELL_JUNCTION_MAINTENANCE | 11/1243 | 41/23056 | 0.2682927 | 4.976473 | 6.083380 | 0.0000076 | 0.0003224 | 0.0002833 | BSN/ERC2/ADGRB3/MTSS1/SHANK2/CBLN1/PARD6A/C1QL1/CAMSAP3/RAB3A/CBLN4 | 11 |
| GOBP_POSITIVE_REGULATION_OF_EXOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_EXOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_EXOCYTOSIS | 16/1243 | 83/23056 | 0.1927711 | 3.575648 | 5.611476 | 0.0000078 | 0.0003319 | 0.0002917 | VSNL1/CDK5R2/CADPS/GATA2/CNR1/SYK/STXBP1/SYT7/SLC4A8/SCAMP5/SMPD3/DOC2B/SYT4/RAB3A/ITGB2/PLA2G3 | 16 |
| GOCC_HIPPOCAMPAL_MOSSY_FIBER_TO_CA3_SYNAPSE | GOCC_HIPPOCAMPAL_MOSSY_FIBER_TO_CA3_SYNAPSE | GOCC_HIPPOCAMPAL_MOSSY_FIBER_TO_CA3_SYNAPSE | 10/1243 | 34/23056 | 0.2941176 | 5.455492 | 6.206175 | 0.0000080 | 0.0003382 | 0.0002972 | SLC30A3/RAPGEF4/GRIK2/CALB1/P2RX3/SYT7/SHANK2/NECTIN1/GRIK4/CACNG2 | 10 |
| GOBP_SMOOTH_MUSCLE_CONTRACTION | GOBP_SMOOTH_MUSCLE_CONTRACTION | GOBP_SMOOTH_MUSCLE_CONTRACTION | 19/1243 | 112/23056 | 0.1696429 | 3.146650 | 5.436208 | 0.0000082 | 0.0003443 | 0.0003025 | PTGER3/CHRNB2/ADORA1/CHRM3/SLC8A1/GRIP2/PROK2/KIT/GUCY1A1/KCNB2/ADRA2A/P2RX3/DRD2/CHRNA3/CHRNB4/ABAT/SSTR2/SULF2/EDN3 | 19 |
| GOBP_RESPONSE_TO_NICOTINE | GOBP_RESPONSE_TO_NICOTINE | GOBP_RESPONSE_TO_NICOTINE | 12/1243 | 49/23056 | 0.2448980 | 4.542532 | 5.925736 | 0.0000082 | 0.0003458 | 0.0003039 | CHRNB2/NTRK1/GRM2/CNR1/CHRNA2/TH/DRD2/CHRNA7/CHRNA3/CHRNB4/ABAT/BCL2 | 12 |
| KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | 32/1243 | 256/23056 | 0.1250000 | 2.318584 | 5.064316 | 0.0000086 | 0.0003600 | 0.0003164 | NPPA/PDE4B/DPT/NMNAT2/ADORA1/VSNL1/KCNK3/FEV/CHL1/FBLN2/CACNA2D2/CADPS/RBP1/AGTR1/PARM1/TUBB2A/RELN/RALYL/PRUNE2/NTRK2/ROR2/CACNA1B/PDE2A/ENO2/GABRB3/DSC1/ZNF208/CHGB/CCN5/TSPAN7/GPRASP1/CHRDL1 | 32 |
| HP_BILATERAL_TONIC_CLONIC_SEIZURE | HP_BILATERAL_TONIC_CLONIC_SEIZURE | HP_BILATERAL_TONIC_CLONIC_SEIZURE | 37/1243 | 317/23056 | 0.1167192 | 2.164987 | 4.985692 | 0.0000087 | 0.0003646 | 0.0003204 | GABRD/CHRNB2/CNTN2/MYT1L/DPYSL5/SCN1A/KIF1A/SLC6A1/CACNA1D/CPLX1/ADGRV1/GABRG2/DLL1/RELN/CHRNA2/KCNQ3/STXBP1/GRIN1/BRSK2/KCNJ11/GAL/CUX2/GABRB3/GABRA5/STX1B/VAMP2/MAPT/TCF4/ATP1A3/CACNG2/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/GRIA3/RAB39B | 37 |
| GOBP_REGULATION_OF_AXONOGENESIS | GOBP_REGULATION_OF_AXONOGENESIS | GOBP_REGULATION_OF_AXONOGENESIS | 23/1243 | 154/23056 | 0.1493506 | 2.770256 | 5.261629 | 0.0000088 | 0.0003661 | 0.0003218 | NGF/TNR/CNTN2/MAP2/SEMA5B/POU4F2/FSTL4/POU3F2/NTRK2/SLIT1/BRSK2/LRRC4C/MAP6/SLITRK1/ISLR2/CDK5R1/MAPT/DCC/BRSK1/CHODL/TIAM1/PAK3/L1CAM | 23 |
| GOBP_DETECTION_OF_LIGHT_STIMULUS | GOBP_DETECTION_OF_LIGHT_STIMULUS | GOBP_DETECTION_OF_LIGHT_STIMULUS | 14/1243 | 66/23056 | 0.2121212 | 3.934567 | 5.699109 | 0.0000090 | 0.0003744 | 0.0003290 | ABCA4/GPR88/SEMA5B/PDE6B/GRM6/GUCA1A/SLC24A2/OPN4/ATP8A2/GRK1/CNGB1/GUCY2D/RS1/CACNA1F | 14 |
| HP_COLOR_VISION_DEFECT | HP_COLOR_VISION_DEFECT | HP_COLOR_VISION_DEFECT | 19/1243 | 113/23056 | 0.1681416 | 3.118803 | 5.389708 | 0.0000093 | 0.0003852 | 0.0003385 | DNAJC6/ABCA4/IL17RD/PROK2/PDE6B/PROM1/GRM6/GUCA1A/RIMS1/FGF17/CDHR1/FGF14/GRK1/TLCD3B/GUCY2D/DCC/PROKR2/ANOS1/CACNA1F | 19 |
| GOBP_DOPAMINE_METABOLIC_PROCESS | GOBP_DOPAMINE_METABOLIC_PROCESS | GOBP_DOPAMINE_METABOLIC_PROCESS | 11/1243 | 42/23056 | 0.2619048 | 4.857986 | 5.973786 | 0.0000097 | 0.0004015 | 0.0003528 | CHRNB2/SNCB/NPY/DDC/DBH/TH/DRD2/GCH1/ABAT/ITGB2/MAOB | 11 |
| GOCC_NON_MOTILE_CILIUM | GOCC_NON_MOTILE_CILIUM | GOCC_NON_MOTILE_CILIUM | 24/1243 | 166/23056 | 0.1445783 | 2.681736 | 5.190980 | 0.0000100 | 0.0004093 | 0.0003597 | ABCA4/RD3/PCARE/MYRIP/PDE6B/PROM1/NPY2R/DCDC2/GUCA1A/PKHD1/RP1L1/CDH23/CDHR1/OPN4/USH1C/SHANK2/DRD2/ATP8A2/GRK1/STRC/CNGB1/GUCY2D/PRCD/CACNA1F | 24 |
| GOBP_NEUROTRANSMITTER_METABOLIC_PROCESS | GOBP_NEUROTRANSMITTER_METABOLIC_PROCESS | GOBP_NEUROTRANSMITTER_METABOLIC_PROCESS | 9/1243 | 28/23056 | 0.3214286 | 5.962073 | 6.271545 | 0.0000102 | 0.0004156 | 0.0003652 | BCHE/DBH/CHAT/TH/PAH/NOS1/PRIMA1/ABAT/MAOB | 9 |
| GOBP_CHLORIDE_TRANSMEMBRANE_TRANSPORT | GOBP_CHLORIDE_TRANSMEMBRANE_TRANSPORT | GOBP_CHLORIDE_TRANSMEMBRANE_TRANSPORT | 14/1243 | 67/23056 | 0.2089552 | 3.875842 | 5.627336 | 0.0000109 | 0.0004425 | 0.0003889 | GABRD/SLC6A1/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/CLCN1/ANO5/SLC4A8/GABRB3/GABRA5/GABRG3/SLC4A1 | 14 |
| HALLMARK_SPERMATOGENESIS | HALLMARK_SPERMATOGENESIS | HALLMARK_SPERMATOGENESIS | 21/1243 | 135/23056 | 0.1555556 | 2.885349 | 5.244478 | 0.0000113 | 0.0004566 | 0.0004013 | OAZ3/DNAJB8/SNAP91/MAP7/PACRG/GRM8/CNIH2/DDX25/ACRBP/NOS1/TUBA3C/CCNA1/HSPA2/SCG3/ACE/DCC/THEG/NEFH/PCSK1N/IL13RA2/TKTL1 | 21 |
| GOMF_GABA_RECEPTOR_ACTIVITY | GOMF_GABA_RECEPTOR_ACTIVITY | GOMF_GABA_RECEPTOR_ACTIVITY | 8/1243 | 22/23056 | 0.3636364 | 6.744972 | 6.435392 | 0.0000113 | 0.0004566 | 0.0004013 | GABRD/GABRG1/GABRG2/GABRP/GABRR2/GABRB3/GABRA5/GABRG3 | 8 |
| GOMF_IONOTROPIC_GLUTAMATE_RECEPTOR_BINDING | GOMF_IONOTROPIC_GLUTAMATE_RECEPTOR_BINDING | GOMF_IONOTROPIC_GLUTAMATE_RECEPTOR_BINDING | 8/1243 | 22/23056 | 0.3636364 | 6.744972 | 6.435392 | 0.0000113 | 0.0004566 | 0.0004013 | IGSF11/SHANK2/DRD2/CDK5R1/CACNG4/SHANK1/SHISA7/CACNG2 | 8 |
| REACTOME_SENSORY_PERCEPTION | REACTOME_SENSORY_PERCEPTION | REACTOME_SENSORY_PERCEPTION | 34/1243 | 284/23056 | 0.1197183 | 2.220616 | 4.940808 | 0.0000116 | 0.0004681 | 0.0004114 | ABCA4/APOB/OTOF/SCN3A/ATP2B2/BSN/CACNA2D2/CACNA1D/RBP1/PDE6B/CHRNA9/GRM4/LHFPL5/GUCA1A/GPC2/CDH23/USH1C/OTOG/SCN4B/SLC17A8/CABP1/GPC5/GRK1/CALM1/STRC/CNGB1/GUCY2D/VAMP2/RAB3A/TMC2/SNAP25/PPEF1/SYN1/SYP | 34 |
| HP_EPILEPTIC_ENCEPHALOPATHY | HP_EPILEPTIC_ENCEPHALOPATHY | HP_EPILEPTIC_ENCEPHALOPATHY | 18/1243 | 105/23056 | 0.1714286 | 3.179772 | 5.343987 | 0.0000121 | 0.0004839 | 0.0004253 | NRXN1/SCN3A/SCN1A/SLC6A1/CACNA2D2/FGF12/CPLX1/GABRG2/PHACTR1/NTRK2/STXBP1/GRIN1/CACNA1B/SLC1A2/CUX2/GABRB3/NEXMIF/DCX | 18 |
| ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN | ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN | ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN | 11/1243 | 43/23056 | 0.2558140 | 4.745009 | 5.867606 | 0.0000125 | 0.0004949 | 0.0004349 | NTRK1/SCN3A/GFRA3/SOX4/CNR1/FAXC/GPR85/SCN3B/HRK/ST8SIA2/PLPPR3 | 11 |
| GOBP_NEUROTRANSMITTER_UPTAKE | GOBP_NEUROTRANSMITTER_UPTAKE | GOBP_NEUROTRANSMITTER_UPTAKE | 11/1243 | 43/23056 | 0.2558140 | 4.745009 | 5.867606 | 0.0000125 | 0.0004949 | 0.0004349 | SLC6A11/SLC6A1/SLC18A1/SLC6A5/SLC1A2/DRD2/NOS1/SLC6A2/SLC1A6/SNAP25/GPM6B | 11 |
| MIKKELSEN_ES_ICP_WITH_H3K27ME3 | MIKKELSEN_ES_ICP_WITH_H3K27ME3 | MIKKELSEN_ES_ICP_WITH_H3K27ME3 | 11/1243 | 43/23056 | 0.2558140 | 4.745009 | 5.867606 | 0.0000125 | 0.0004949 | 0.0004349 | HPCA/COL24A1/KCNJ9/PDE6B/PCDHB6/SFTPC/TH/CALCB/CHST1/CPLX3/RNF112 | 11 |
| REACTOME_PLATELET_HOMEOSTASIS | REACTOME_PLATELET_HOMEOSTASIS | REACTOME_PLATELET_HOMEOSTASIS | 16/1243 | 86/23056 | 0.1860465 | 3.450916 | 5.435726 | 0.0000125 | 0.0004964 | 0.0004363 | GNG4/APOB/SLC8A1/PDE1A/ATP2B2/PRKG2/GUCY1A1/P2RX3/PDE2A/NOS1/P2RX7/SLC8A3/CALM1/GNG8/SLC8A2/ATP2B3 | 16 |
| STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | 27/1243 | 202/23056 | 0.1336634 | 2.479278 | 5.040862 | 0.0000126 | 0.0004969 | 0.0004367 | LRRC7/PLPPR5/SLC8A1/FBXO41/KIF5C/SLC6A1/SYN2/BSN/PPP2R2C/ATP8A1/CPLX2/GPRIN1/CNR1/TMEM178B/DLGAP2/OLFM1/SLC1A2/NECTIN1/B3GAT1/RIMBP2/NRXN3/CDK5R1/RNF165/TCF4/ATP1A3/PRKCG/GRK3 | 27 |
| GOMF_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | GOMF_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | GOMF_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | 41/1243 | 373/23056 | 0.1099196 | 2.038862 | 4.828614 | 0.0000127 | 0.0005000 | 0.0004394 | PLCH2/NT5C1A/DNAJC6/PDE4B/PLPPR5/PLPPR4/DUSP23/CHRM3/PPM1B/PDE1A/PLCD4/PTPRN/SGPP2/PLCL2/PPM1L/PDE6B/ENPP6/PLCXD3/GPLD1/PTPRN2/MTMR7/DUSP4/DUSP26/EYA1/ENPP2/FBP1/PLPPR1/PTPN5/MPPED2/CHRM1/PDE2A/GDPD4/PTPRO/PLD4/SMPD3/PPM1E/PLPPR3/PTPRT/EYA2/INPP5J/PPEF1 | 41 |
| REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | 31/1243 | 249/23056 | 0.1244980 | 2.309273 | 4.958566 | 0.0000128 | 0.0005004 | 0.0004397 | SLC44A5/SLC22A15/RHBG/SLC30A3/SLC8A1/SLC6A11/SLC6A1/SLC38A3/SLC16A10/SLC18A1/SLC24A2/LCN12/SLC29A3/SLC6A5/SLC1A2/SLC22A6/SLCO1B1/SLC4A8/SLC6A15/SLC17A8/SLC8A3/CALM1/SLC25A29/RHCG/SLC6A2/SLC4A1/SLC1A6/SLC8A2/SLC32A1/SLC38A5/SLC7A3 | 31 |
| GOBP_DETECTION_OF_VISIBLE_LIGHT | GOBP_DETECTION_OF_VISIBLE_LIGHT | GOBP_DETECTION_OF_VISIBLE_LIGHT | 12/1243 | 51/23056 | 0.2352941 | 4.364394 | 5.741709 | 0.0000128 | 0.0005004 | 0.0004397 | ABCA4/GPR88/SEMA5B/PDE6B/GRM6/OPN4/ATP8A2/GRK1/CNGB1/GUCY2D/RS1/CACNA1F | 12 |
| MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3 | MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3 | MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3 | 20/1243 | 126/23056 | 0.1587302 | 2.944234 | 5.223867 | 0.0000133 | 0.0005192 | 0.0004563 | COL24A1/RGS8/MEIS1/PROKR1/NCKAP5/MST1R/NPY2R/GUCY1A1/PLCXD3/MEGF10/PHYHIP/ADARB2/TMEM26/MRGPRE/TMEM63C/KCNK10/ISLR2/MC4R/PAK5/CHODL | 20 |
| GOBP_SYNAPTIC_TRANSMISSION_CHOLINERGIC | GOBP_SYNAPTIC_TRANSMISSION_CHOLINERGIC | GOBP_SYNAPTIC_TRANSMISSION_CHOLINERGIC | 9/1243 | 29/23056 | 0.3103448 | 5.756485 | 6.118245 | 0.0000140 | 0.0005428 | 0.0004770 | CHRNB2/CHRM3/CHRNA1/CHRNA2/RIC3/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4 | 9 |
| GOCC_PRESYNAPTIC_ACTIVE_ZONE_MEMBRANE | GOCC_PRESYNAPTIC_ACTIVE_ZONE_MEMBRANE | GOCC_PRESYNAPTIC_ACTIVE_ZONE_MEMBRANE | 9/1243 | 29/23056 | 0.3103448 | 5.756485 | 6.118245 | 0.0000140 | 0.0005428 | 0.0004770 | NTNG1/SYT11/OTOF/ATP2B2/STXBP1/ADRA2A/NECTIN1/CPLX3/STX1B | 9 |
| MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 | 21/1243 | 137/23056 | 0.1532847 | 2.843227 | 5.165374 | 0.0000142 | 0.0005485 | 0.0004820 | RGS8/SUSD4/PCARE/PROKR1/MST1R/SPTSSB/NPY2R/GUCY1A1/PHYHIP/PAX5/ADARB2/TMEM26/TSPAN11/CCDC38/SLITRK1/ISLR2/NOL4/NCAN/PAK5/COX4I2/CHODL | 21 |
| CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | 47/1243 | 454/23056 | 0.1035242 | 1.920237 | 4.727316 | 0.0000149 | 0.0005744 | 0.0005048 | CRYBG2/VAV3/KIAA0040/GOLT1A/IRF6/CAPN8/MGAT4A/ABCA12/IGFBP2/CACNA1D/CTNND2/SELENOP/PCDH1/CD24/MYB/MAP7/ARFGEF3/ESR1/ICA1/AZGP1/KDM7A/RASEF/FGD3/FBP1/RALGPS1/NEBL/PPFIBP2/SYT7/SHANK2/RERG/DEGS2/SLC25A29/SPINT1/CKMT1B/ARRDC4/ABAT/SETD6/RAB11FIP4/CACNG4/HID1/CAMSAP3/PREX1/ABCG1/RSPH1/SLC37A1/INPP5J/BEX5 | 47 |
| GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT | GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT | GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT | 31/1243 | 251/23056 | 0.1235060 | 2.290872 | 4.908688 | 0.0000150 | 0.0005762 | 0.0005064 | NPPA/OPRD1/HPCA/PDE4B/ATP1B1/RYR2/SLC8A1/CXCR4/CACNA1D/ANK2/GRM6/FYN/ADCYAP1R1/GRIN1/ADRA2A/P2RX3/DRD2/NOS1/PLA2G1B/P2RX7/JPH4/AKAP6/HSPA2/CALM1/JPH3/ACE/CACNG1/BCL2/JSRP1/HRC/TMC2 | 31 |
| REACTOME_REGULATION_OF_INSULIN_SECRETION | REACTOME_REGULATION_OF_INSULIN_SECRETION | REACTOME_REGULATION_OF_INSULIN_SECRETION | 15/1243 | 78/23056 | 0.1923077 | 3.567052 | 5.421087 | 0.0000154 | 0.0005875 | 0.0005163 | GNG4/CHRM3/RAPGEF4/CACNA2D2/CACNA1D/ADCY5/GLP1R/STXBP1/ADRA2A/KCNJ11/KCNC2/VAMP2/GNG8/SYT5/SNAP25 | 15 |
| GOBP_REGULATION_OF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_POSTSYNAPTIC_NEUROTRANSMITTER_RECEPTOR_ACTIVITY | 7/1243 | 17/23056 | 0.4117647 | 7.637689 | 6.535367 | 0.0000157 | 0.0005959 | 0.0005237 | DLGAP3/DLGAP2/CNIH2/BEGAIN/CACNG5/CACNG4/SHISA7 | 7 |
| HP_TIBIAL_TORSION | HP_TIBIAL_TORSION | HP_TIBIAL_TORSION | 7/1243 | 17/23056 | 0.4117647 | 7.637689 | 6.535367 | 0.0000157 | 0.0005959 | 0.0005237 | GABRD/SCN1A/ADGRV1/GABRG2/STXBP1/SLC29A3/STX1B | 7 |
| GOMF_CALCIUM_CHANNEL_REGULATOR_ACTIVITY | GOMF_CALCIUM_CHANNEL_REGULATOR_ACTIVITY | GOMF_CALCIUM_CHANNEL_REGULATOR_ACTIVITY | 11/1243 | 44/23056 | 0.2500000 | 4.637168 | 5.764650 | 0.0000158 | 0.0005977 | 0.0005252 | HPCAL4/NRXN1/GRM2/NPY2R/NPY/AMBP/NRXN2/CALM1/CACNG4/CACNG1/CACNG7 | 11 |
| GOBP_SYNAPTIC_VESICLE_LOCALIZATION | GOBP_SYNAPTIC_VESICLE_LOCALIZATION | GOBP_SYNAPTIC_VESICLE_LOCALIZATION | 12/1243 | 52/23056 | 0.2307692 | 4.280463 | 5.653216 | 0.0000158 | 0.0005977 | 0.0005252 | KIF5C/MAP2/SYN2/SNAP91/BRSK2/CNIH2/KIF5A/PCDH17/RAB3A/BRSK1/SYNDIG1/SYN1 | 12 |
| REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | 6/1243 | 12/23056 | 0.5000000 | 9.274336 | 6.843926 | 0.0000169 | 0.0006345 | 0.0005576 | CHRNB2/CHRNA1/CHRND/CHRNA2/CHRNA3/CHRNB4 | 6 |
| REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS | REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS | REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS | 6/1243 | 12/23056 | 0.5000000 | 9.274336 | 6.843926 | 0.0000169 | 0.0006345 | 0.0005576 | SLC8A1/ATP2B2/SLC8A3/CALM1/SLC8A2/ATP2B3 | 6 |
| GOCC_MAIN_AXON | GOCC_MAIN_AXON | GOCC_MAIN_AXON | 13/1243 | 61/23056 | 0.2131148 | 3.952996 | 5.512790 | 0.0000178 | 0.0006643 | 0.0005838 | LRRC7/ADORA1/NFASC/CNTN2/SCN1A/MAP2/CNTNAP2/KCNQ3/KCNC1/SLC1A2/KCNC2/MAPT/TUBB4A | 13 |
| GOBP_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 21/1243 | 139/23056 | 0.1510791 | 2.802317 | 5.087685 | 0.0000178 | 0.0006643 | 0.0005838 | PDE4B/RGS5/RGS16/RGS13/CNTN2/GNG4/RGS7/GPR27/KCTD8/KCTD16/MRAP2/OPRM1/GRM5/DRD2/GRK1/CHGA/RGS11/GUCY2D/GRK3/SYP/GPRASP1 | 21 |
| GOBP_REGULATION_OF_PEPTIDE_TRANSPORT | GOBP_REGULATION_OF_PEPTIDE_TRANSPORT | GOBP_REGULATION_OF_PEPTIDE_TRANSPORT | 25/1243 | 183/23056 | 0.1366120 | 2.533972 | 4.973267 | 0.0000179 | 0.0006643 | 0.0005838 | ADORA1/VSNL1/KLF7/ABCA12/MYRIP/GPR27/ADCY5/ISL1/SOX4/GPLD1/TFAP2B/CNR1/RFX6/ICA1/TFR2/ADRA2A/BRSK2/KCNJ11/SYT7/DRD2/IRS2/CHGA/ABAT/DOC2B/SNAP25 | 25 |
| HP_FOCAL_IMPAIRED_AWARENESS_SEIZURE | HP_FOCAL_IMPAIRED_AWARENESS_SEIZURE | HP_FOCAL_IMPAIRED_AWARENESS_SEIZURE | 18/1243 | 108/23056 | 0.1666667 | 3.091445 | 5.200516 | 0.0000180 | 0.0006664 | 0.0005856 | GABRD/MYT1L/SCN1A/KIF1A/CACNA1D/ADGRV1/GABRG2/DLL1/RELN/KCNQ3/STXBP1/GRIN1/BRSK2/GAL/PDE2A/STX1B/TCF4/CACNG2 | 18 |
| MEISSNER_NPC_HCP_WITH_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K27ME3 | 15/1243 | 79/23056 | 0.1898734 | 3.521900 | 5.359881 | 0.0000180 | 0.0006664 | 0.0005856 | PRKCZ/PAX7/WNT10A/ATP2B2/FSTL4/NELL1/C1QTNF4/DRD2/FOXN4/DIO3/GPR139/CA10/ST8SIA3/VSTM2L/KCNK15 | 15 |
| GOBP_NEURON_PROJECTION_EXTENSION | GOBP_NEURON_PROJECTION_EXTENSION | GOBP_NEURON_PROJECTION_EXTENSION | 24/1243 | 172/23056 | 0.1395349 | 2.588187 | 4.990686 | 0.0000183 | 0.0006718 | 0.0005904 | PRKCZ/TNR/BCL11A/CXCR4/MAP2/SEMA5B/TMEM108/POU4F2/RIMS1/DPYSL2/OLFM1/SLIT1/RASAL1/ISLR2/ST8SIA2/CDK5R1/MAPT/SYT4/UNC13A/SYT3/CACNG7/EDN3/NLGN3/L1CAM | 24 |
| LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES | LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES | LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES | 10/1243 | 37/23056 | 0.2702703 | 5.013155 | 5.831818 | 0.0000183 | 0.0006718 | 0.0005904 | HPCA/DNAJC6/KIF5C/MAP2/BSN/ANK2/NSG2/INA/RPH3A/CHGB | 10 |
| HP_DIALEPTIC_SEIZURE | HP_DIALEPTIC_SEIZURE | HP_DIALEPTIC_SEIZURE | 28/1243 | 218/23056 | 0.1284404 | 2.382398 | 4.895452 | 0.0000186 | 0.0006806 | 0.0005981 | GABRD/MYT1L/SCN1A/KIF1A/SLC6A1/SATB1/CACNA1D/ADGRV1/GABRG2/DLL1/RELN/KCNQ3/STXBP1/GRIN1/BRSK2/GAL/PDE2A/CUX2/GABRB3/STX1B/TCF4/CACNG2/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/RAB39B | 28 |
| SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN | 12/1243 | 53/23056 | 0.2264151 | 4.199699 | 5.566924 | 0.0000195 | 0.0007107 | 0.0006246 | ELAVL4/TAGLN3/GAP43/LIX1/NSG2/NTRK2/OLFM1/CALCB/FXYD6-FXYD2/PCDH8/SYT4/ELAVL3 | 12 |
| GOBP_NEURON_MATURATION | GOBP_NEURON_MATURATION | GOBP_NEURON_MATURATION | 11/1243 | 45/23056 | 0.2444444 | 4.534120 | 5.664743 | 0.0000199 | 0.0007245 | 0.0006367 | EPHA8/CNTN2/BCL11A/FEV/ADGRB3/ACTL6B/CNTNAP2/CDKN1C/SRRM4/C1QL1/BCL2 | 11 |
| KEGG_MAPK_SIGNALING_PATHWAY | KEGG_MAPK_SIGNALING_PATHWAY | KEGG_MAPK_SIGNALING_PATHWAY | 32/1243 | 267/23056 | 0.1198502 | 2.223062 | 4.798460 | 0.0000203 | 0.0007379 | 0.0006485 | NGF/NTRK1/PPM1B/CACNA2D2/CACNA1D/FGF12/PDGFRA/FGF17/DUSP4/NTRK2/GADD45G/CACNA1B/PTPN5/MAPK8IP1/FGF19/FGF6/PLA2G1B/FGF14/HSPA2/FGF11/MAPT/CACNG5/CACNG4/CACNG1/MAP4K1/PRKCG/CACNG7/PLA2G3/CACNG2/MAPK8IP2/CACNA1F/RPS6KA6 | 32 |
| GOBP_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY | 13/1243 | 62/23056 | 0.2096774 | 3.889238 | 5.437913 | 0.0000214 | 0.0007740 | 0.0006802 | NTRK1/NRXN1/CLSTN2/SLITRK3/ADGRB3/NTRK2/VSTM5/CUX2/SLITRK1/ST8SIA2/CBLN1/SYNDIG1/NLGN3 | 13 |
| GOBP_CARBOXYLIC_ACID_TRANSPORT | GOBP_CARBOXYLIC_ACID_TRANSPORT | GOBP_CARBOXYLIC_ACID_TRANSPORT | 33/1243 | 280/23056 | 0.1178571 | 2.186094 | 4.766720 | 0.0000215 | 0.0007749 | 0.0006810 | SLC6A17/ADORA1/AGXT/SLC6A11/SLC6A1/SLC38A3/GRM2/SLC10A4/SLC35D3/ABCB4/NTRK2/SYK/STXBP1/SLC6A5/SLC1A2/SLC22A6/FGF19/DRD2/SLCO1B1/SLC6A15/SLC17A8/PLA2G1B/P2RX7/SLC25A29/ABAT/ACE/SYT4/SLC1A6/SLC32A1/HRH3/PLA2G3/SLC38A5/SLC7A3 | 33 |
| WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS | WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS | WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS | 22/1243 | 152/23056 | 0.1447368 | 2.684676 | 4.974426 | 0.0000226 | 0.0008135 | 0.0007149 | PRKCZ/RGS5/ATP1B1/RGS16/GNG4/RYR2/CHRM3/RGS7/SLC8A1/ATP2B2/CACNA1D/ADCY5/PKIB/CACNA1B/CHRM1/SLC8A3/CALM1/GJD2/RGS11/GNG8/PRKCG/ATP2B3 | 22 |
| GOBP_REGULATION_OF_POTASSIUM_ION_TRANSPORT | GOBP_REGULATION_OF_POTASSIUM_ION_TRANSPORT | GOBP_REGULATION_OF_POTASSIUM_ION_TRANSPORT | 18/1243 | 110/23056 | 0.1636364 | 3.035237 | 5.107617 | 0.0000233 | 0.0008341 | 0.0007331 | NPPA/ATP1B1/ADORA1/RGS7/DPP10/CACNA1D/ANK2/KCNIP1/VIP/ADRA2A/KCNC1/GAL/DRD2/KCNC2/NOS1/AKAP6/VAMP2/EDN3 | 18 |
| GOCC_CALYX_OF_HELD | GOCC_CALYX_OF_HELD | GOCC_CALYX_OF_HELD | 7/1243 | 18/23056 | 0.3888889 | 7.213373 | 6.295086 | 0.0000245 | 0.0008750 | 0.0007689 | KCNA3/ADORA1/CPLX1/CPLX2/CALB1/KCNC1/PRKCG | 7 |
| GOMF_SODIUM_CHANNEL_ACTIVITY | GOMF_SODIUM_CHANNEL_ACTIVITY | GOMF_SODIUM_CHANNEL_ACTIVITY | 11/1243 | 46/23056 | 0.2391304 | 4.435552 | 5.567723 | 0.0000249 | 0.0008875 | 0.0007800 | GRIK3/HCN3/SCN3A/SCN1A/SCN7A/ASIC4/SCN5A/GRIK2/SCN4B/GRIK4/SCN3B | 11 |
| GOBP_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 14/1243 | 72/23056 | 0.1944444 | 3.606686 | 5.288136 | 0.0000258 | 0.0009151 | 0.0008042 | DISP3/RAP1GAP/CNTN2/SIX3/MEIS1/CNTN4/SOX2/POU4F2/ISL1/DLL1/ASCL1/DTX1/ZNF536/BMP7 | 14 |
| GOBP_POSITIVE_REGULATION_OF_NEUROGENESIS | GOBP_POSITIVE_REGULATION_OF_NEUROGENESIS | GOBP_POSITIVE_REGULATION_OF_NEUROGENESIS | 28/1243 | 222/23056 | 0.1261261 | 2.339472 | 4.787179 | 0.0000260 | 0.0009221 | 0.0008103 | NGF/SOX11/CXCR4/FAIM/KIT/POU4F2/TLR2/TTBK1/OPRM1/RELN/NTRK2/NEURL1/RASSF10/MAP6/GRM5/DRD2/ASCL1/CUX2/SLITRK1/SPINT1/ISLR2/RNF112/MAPT/ACE/CHODL/TIAM1/PAK3/L1CAM | 28 |
| GOBP_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | GOBP_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | GOBP_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | 29/1243 | 234/23056 | 0.1239316 | 2.298767 | 4.766755 | 0.0000262 | 0.0009236 | 0.0008117 | PRKCZ/NGF/TNR/BCL11A/CXCR4/MAP2/SEMA5B/TMEM108/POU4F2/SFRP2/FSTL4/RIMS1/ESR1/DPYSL2/OLFM1/SLIT1/RASAL1/ISLR2/ST8SIA2/CDK5R1/MAPT/SYT4/DCC/UNC13A/SYT3/CACNG7/EDN3/NLGN3/L1CAM | 29 |
| GOBP_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOBP_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOBP_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 16/1243 | 91/23056 | 0.1758242 | 3.261305 | 5.159493 | 0.0000262 | 0.0009236 | 0.0008117 | NPPA/HPCA/PDE4B/ATP1B1/RYR2/ANK2/ADRA2A/DRD2/NOS1/JPH4/AKAP6/HSPA2/CALM1/JPH3/JSRP1/HRC | 16 |
| CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | 41/1243 | 385/23056 | 0.1064935 | 1.975313 | 4.606802 | 0.0000268 | 0.0009417 | 0.0008276 | RIIAD1/KIAA0040/GOLT1A/HK2/MGAT4A/CACNA2D2/CACNA1D/CLSTN2/PPP2R2C/CRACD/CTNND2/ELOVL2/MYB/ARFGEF3/ESR1/ICA1/KDM7A/ZNF704/RALGPS1/GARNL3/C10orf82/SHANK2/SLC4A8/DACH1/F7/TTC6/C14orf132/DEGS2/SLC25A29/SBK1/MAPT/CACNG4/HID1/ONECUT2/CAMSAP3/PRR36/PREX1/ABCG1/RSPH1/SLC37A1/INPP5J | 41 |
| GOCC_LEADING_EDGE_MEMBRANE | GOCC_LEADING_EDGE_MEMBRANE | GOCC_LEADING_EDGE_MEMBRANE | 24/1243 | 176/23056 | 0.1363636 | 2.529364 | 4.861830 | 0.0000269 | 0.0009421 | 0.0008279 | OPRD1/HPCA/THEM4/ADORA1/ATP2B2/GABRG1/ADGRV1/PSD2/GABRG2/UNC5A/PACSIN1/OPRM1/CNTNAP2/SH2D3C/PSD/KCNC1/SLC1A2/KCNC2/GABRA5/GABRG3/MAPT/KCNC3/SHISA7/LAMP5 | 24 |
| GOBP_CAMERA_TYPE_EYE_MORPHOGENESIS | GOBP_CAMERA_TYPE_EYE_MORPHOGENESIS | GOBP_CAMERA_TYPE_EYE_MORPHOGENESIS | 19/1243 | 122/23056 | 0.1557377 | 2.888728 | 4.993094 | 0.0000286 | 0.0009979 | 0.0008770 | PROX1/SOX11/SIX3/MEIS1/CRYGB/PROM1/TFAP2B/DLL1/TWIST1/CALB1/NTRK2/TH/USH1C/NECTIN1/FOXN4/ATP8A2/DIO3/BMP7/RS1 | 19 |
| HP_GENERALIZED_TONIC_SEIZURE | HP_GENERALIZED_TONIC_SEIZURE | HP_GENERALIZED_TONIC_SEIZURE | 15/1243 | 82/23056 | 0.1829268 | 3.393050 | 5.182040 | 0.0000287 | 0.0009979 | 0.0008770 | MYT1L/SCN1A/KIF1A/SATB1/ADGRV1/GABRG2/DLL1/KCNQ3/STXBP1/GRIN1/BRSK2/CUX2/GABRB3/TCF4/CACNG2 | 15 |
| MIKKELSEN_IPS_ICP_WITH_H3K27ME3 | MIKKELSEN_IPS_ICP_WITH_H3K27ME3 | MIKKELSEN_IPS_ICP_WITH_H3K27ME3 | 12/1243 | 55/23056 | 0.2181818 | 4.046983 | 5.400556 | 0.0000290 | 0.0010064 | 0.0008844 | ABCA4/LINGO4/KCNJ9/TFAP2B/CNTNAP2/PAX5/LRRC4C/CHST1/FGF14/CPLX3/NOL4/INPP5J | 12 |
| GOMF_CALMODULIN_BINDING | GOMF_CALMODULIN_BINDING | GOMF_CALMODULIN_BINDING | 26/1243 | 200/23056 | 0.1300000 | 2.411327 | 4.785233 | 0.0000296 | 0.0010229 | 0.0008989 | RGS16/KCNH1/RYR2/SLC8A1/ADD2/PDE1A/MAP2/ATP2B2/ARPP21/SCN5A/CAMKV/GAP43/KCNQ3/GRIN1/SYT7/MAP6/NOS1/KCNH5/SLC8A3/VAMP2/RIT2/CAMSAP3/UNC13A/KCNN1/SLC8A2/ATP2B3 | 26 |
| GOCC_AXOLEMMA | GOCC_AXOLEMMA | GOCC_AXOLEMMA | 6/1243 | 13/23056 | 0.4615385 | 8.560926 | 6.509349 | 0.0000300 | 0.0010350 | 0.0009096 | ADORA1/CNTNAP2/KCNC1/SLC1A2/KCNC2/MAPT | 6 |
| GOBP_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORT | GOBP_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORT | GOBP_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORT | 16/1243 | 92/23056 | 0.1739130 | 3.225856 | 5.106551 | 0.0000302 | 0.0010378 | 0.0009120 | GABRD/SLC6A1/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/CLCN1/ANO5/GRM5/SLC4A8/GABRB3/GABRA5/GABRG3/SLC4A1/SLC37A1 | 16 |
| CHYLA_CBFA2T3_TARGETS_UP | CHYLA_CBFA2T3_TARGETS_UP | CHYLA_CBFA2T3_TARGETS_UP | 41/1243 | 387/23056 | 0.1059432 | 1.965105 | 4.570611 | 0.0000302 | 0.0010378 | 0.0009120 | CYP2J2/C1orf21/IRF6/CXCR4/VILL/CXXC4/AFAP1L1/HK3/SH3BGRL2/ICA1/MGAM/FBP1/TMOD1/CELF2/ATRNL1/GFRA1/PPFIBP2/LMO1/SPI1/PDE2A/ABCD2/SLC4A8/P2RX7/PELI2/PLD4/SCAMP5/TM6SF1/CDK5R1/EPX/SSTR2/AATK/PLPPR3/TLE6/NKG7/CCM2L/SLC32A1/ABCG1/KLF8/BEX2/SEPTIN6/GRIA3 | 41 |
| DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | 13/1243 | 64/23056 | 0.2031250 | 3.767699 | 5.292744 | 0.0000306 | 0.0010449 | 0.0009183 | VAV3/ALK/CXCR4/ANK2/JAKMIP2/ANK1/EYA1/EPB41L4B/NEBL/NELL1/ABAT/GPM6B/DCX | 13 |
| GOMF_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_ADHESION_MEDIATOR_ACTIVITY | 13/1243 | 64/23056 | 0.2031250 | 3.767699 | 5.292744 | 0.0000306 | 0.0010449 | 0.0009183 | NTNG1/NFASC/CNTN2/CNTN6/CNTN4/CD200/LRRC4C/DSCAML1/TRIM29/CNTN1/STXBP6/DSC2/VSTM2L | 13 |
| GOBP_RESPONSE_TO_CALCIUM_ION | GOBP_RESPONSE_TO_CALCIUM_ION | GOBP_RESPONSE_TO_CALCIUM_ION | 21/1243 | 144/23056 | 0.1458333 | 2.705015 | 4.899348 | 0.0000307 | 0.0010453 | 0.0009187 | HPCA/SYT11/KCNH1/RYR2/SLC6A1/SCN5A/ADGRV1/GPLD1/GUCA1A/DMTN/SYT8/SYT13/SYT7/TPH2/RASAL1/P2RX7/CALM1/SYT4/SYT3/SYT5/CACNG2 | 21 |
| GOBP_RESPONSE_TO_COCAINE | GOBP_RESPONSE_TO_COCAINE | GOBP_RESPONSE_TO_COCAINE | 11/1243 | 47/23056 | 0.2340426 | 4.341179 | 5.473438 | 0.0000309 | 0.0010503 | 0.0009230 | ELAVL4/CHRNB2/SLC6A1/GRM2/CNR1/OPRM1/SLC1A2/DRD2/ST8SIA2/ABAT/CACNG4 | 11 |
| GOBP_CELLULAR_RESPONSE_TO_CALCIUM_ION | GOBP_CELLULAR_RESPONSE_TO_CALCIUM_ION | GOBP_CELLULAR_RESPONSE_TO_CALCIUM_ION | 15/1243 | 83/23056 | 0.1807229 | 3.352170 | 5.124592 | 0.0000333 | 0.0011258 | 0.0009894 | HPCA/SYT11/KCNH1/SCN5A/ADGRV1/GPLD1/GUCA1A/DMTN/SYT8/SYT13/SYT7/RASAL1/SYT4/SYT3/SYT5 | 15 |
| GOBP_RESPONSE_TO_ACETYLCHOLINE | GOBP_RESPONSE_TO_ACETYLCHOLINE | GOBP_RESPONSE_TO_ACETYLCHOLINE | 9/1243 | 32/23056 | 0.2812500 | 5.216814 | 5.698092 | 0.0000339 | 0.0011452 | 0.0010064 | CHRNB2/RGS8/CHRM3/OPRM1/CHRM1/CHRNA7/CHRNA3/CDK5R1/HRH3 | 9 |
| GOBP_RESPONSE_TO_METAL_ION | GOBP_RESPONSE_TO_METAL_ION | GOBP_RESPONSE_TO_METAL_ION | 38/1243 | 350/23056 | 0.1085714 | 2.013856 | 4.562474 | 0.0000342 | 0.0011510 | 0.0010115 | HPCA/SYT11/KCNH1/RYR2/KCNK3/SLC30A3/HAAO/IGFBP2/SLC6A1/SCN5A/KIT/ADGRV1/GPLD1/GUCA1A/TFR2/DMTN/FBP1/SYT8/TH/KCNC1/SYT13/SYT7/DRD2/TPH2/KCNC2/ASCL1/RASAL1/P2RX7/CALM1/ABAT/SMPD3/MAPT/SYT4/BCL2/SYT3/SYT5/CACNG2/MAOB | 38 |
| GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | 17/1243 | 103/23056 | 0.1650485 | 3.061431 | 5.005278 | 0.0000347 | 0.0011622 | 0.0010213 | RYR2/SLC8A1/ANK2/FYN/ADCYAP1R1/GRIN1/P2RX3/NOS1/PLA2G1B/P2RX7/JPH4/AKAP6/CALM1/JPH3/BCL2/JSRP1/HRC | 17 |
| HP_ATONIC_SEIZURE | HP_ATONIC_SEIZURE | HP_ATONIC_SEIZURE | 17/1243 | 103/23056 | 0.1650485 | 3.061431 | 5.005278 | 0.0000347 | 0.0011622 | 0.0010213 | GABRD/MYT1L/SCN1A/KIF1A/SLC6A1/ADGRV1/GABRG2/DLL1/STXBP1/GRIN1/BRSK2/CUX2/GABRB3/STX1B/TCF4/CACNG2/NEXMIF | 17 |
| GOBP_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_NEUROTRANSMITTER_RECEPTOR_LEVELS | GOBP_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_NEUROTRANSMITTER_RECEPTOR_LEVELS | GOBP_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_NEUROTRANSMITTER_RECEPTOR_LEVELS | 12/1243 | 56/23056 | 0.2142857 | 3.974715 | 5.320298 | 0.0000351 | 0.0011685 | 0.0010269 | PRKCZ/HPCA/GRIP2/CPLX1/NSG1/GSG1L/STX1B/CACNG5/CACNG4/CACNG7/SNAP25/CACNG2 | 12 |
| GOBP_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | GOBP_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | GOBP_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | 12/1243 | 56/23056 | 0.2142857 | 3.974715 | 5.320298 | 0.0000351 | 0.0011685 | 0.0010269 | RIMS3/CNR1/ADRA2A/DRD2/SLC4A8/SYT4/RAB3A/PRKCG/RIMS4/SEPTIN5/SYN1/SYP | 12 |
| MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED | MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED | MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED | 29/1243 | 238/23056 | 0.1218487 | 2.260132 | 4.664728 | 0.0000360 | 0.0011944 | 0.0010496 | OLFM3/RIIAD1/DNAJB8/PCDHA1/PCDHB10/NRSN1/HMGCLL1/CLVS2/CNTNAP2/GDAP1/KCNJ11/CNIH2/FGF6/ACRBP/RPH3A/NOS1/PIWIL1/SCG3/SSTR2/TLE6/EDN3/CACNG2/NR0B1/PCSK1N/SYP/TBX22/BEX1/BEX4/CHRDL1 | 29 |
| GOBP_NEUROTRANSMITTER_RECEPTOR_INTERNALIZATION | GOBP_NEUROTRANSMITTER_RECEPTOR_INTERNALIZATION | GOBP_NEUROTRANSMITTER_RECEPTOR_INTERNALIZATION | 7/1243 | 19/23056 | 0.3684211 | 6.833722 | 6.072534 | 0.0000370 | 0.0012138 | 0.0010667 | HPCA/GSG1L/CACNG5/CACNG4/CACNG7/SNAP25/CACNG2 | 7 |
| GOBP_SEROTONIN_TRANSPORT | GOBP_SEROTONIN_TRANSPORT | GOBP_SEROTONIN_TRANSPORT | 7/1243 | 19/23056 | 0.3684211 | 6.833722 | 6.072534 | 0.0000370 | 0.0012138 | 0.0010667 | CNR1/SLC18A1/SYK/NOS1/HRH3/GPM6B/MAOB | 7 |
| GOBP_SYNAPTIC_VESICLE_PRIMING | GOBP_SYNAPTIC_VESICLE_PRIMING | GOBP_SYNAPTIC_VESICLE_PRIMING | 7/1243 | 19/23056 | 0.3684211 | 6.833722 | 6.072534 | 0.0000370 | 0.0012138 | 0.0010667 | OTOF/ERC2/STXBP1/STX1B/UNC13A/RAB3A/SNAP25 | 7 |
| GOMF_ANKYRIN_BINDING | GOMF_ANKYRIN_BINDING | GOMF_ANKYRIN_BINDING | 7/1243 | 19/23056 | 0.3684211 | 6.833722 | 6.072534 | 0.0000370 | 0.0012138 | 0.0010667 | RHBG/SLC8A1/SCN5A/CACNA1D/KCNJ11/RHCG/SLC4A1 | 7 |
| WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION | WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION | WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION | 10/1243 | 40/23056 | 0.2500000 | 4.637168 | 5.495901 | 0.0000384 | 0.0012582 | 0.0011057 | SLC8A1/ATP2B2/CALB1/KCNQ3/GRIN1/CHRM1/GRM5/TPH2/BCL2/ATP2B3 | 10 |
| GOBP_DEVELOPMENTAL_CELL_GROWTH | GOBP_DEVELOPMENTAL_CELL_GROWTH | GOBP_DEVELOPMENTAL_CELL_GROWTH | 28/1243 | 227/23056 | 0.1233480 | 2.287942 | 4.655070 | 0.0000391 | 0.0012758 | 0.0011212 | PRKCZ/NGF/TNR/BCL11A/CXCR4/MAP2/SEMA5B/TMEM108/POU4F2/FSTL4/RIMS1/DPYSL2/OLFM1/SLIT1/RASAL1/AKAP6/ISLR2/ST8SIA2/CDK5R1/MAPT/SYT4/DCC/UNC13A/SYT3/CACNG7/EDN3/NLGN3/L1CAM | 28 |
| HP_INABILITY_TO_WALK | HP_INABILITY_TO_WALK | HP_INABILITY_TO_WALK | 31/1243 | 264/23056 | 0.1174242 | 2.178064 | 4.595576 | 0.0000405 | 0.0013182 | 0.0011585 | DNAJC6/NTNG1/SLC6A17/SIX3/DYSF/CTNNA2/SCN3A/SCN1A/UNC80/CHRND/KIF1A/SATB1/CACNA2D2/FGF12/CPLX1/DLL1/ACTL6B/GDAP1/NTRK2/STXBP1/GRIN1/CACNA1B/NODAL/SLC1A2/GRIA4/ATP8A2/MAGEL2/VAMP2/MAPT/ASXL3/MAST1 | 31 |
| LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN | 18/1243 | 115/23056 | 0.1565217 | 2.903271 | 4.884315 | 0.0000430 | 0.0013956 | 0.0012265 | MANEAL/PTGER3/VAV3/FRZB/ZDHHC11/MYB/IL20RA/ESR1/AZGP1/TPD52/DNAJC12/DACH1/ABAT/RTN4RL1/HID1/LAMP5/RSPH1/INPP5J | 18 |
| MIKKELSEN_ES_HCP_WITH_H3_UNMETHYLATED | MIKKELSEN_ES_HCP_WITH_H3_UNMETHYLATED | MIKKELSEN_ES_HCP_WITH_H3_UNMETHYLATED | 13/1243 | 66/23056 | 0.1969697 | 3.653526 | 5.153311 | 0.0000431 | 0.0013969 | 0.0012276 | OLFM3/RIIAD1/DNAJB8/PCDHB10/GOLGA7B/FGF6/RPH3A/NOS1/PIWIL1/SSTR2/CACNG2/SYP/TBX22 | 13 |
| HP_FOCAL_MOTOR_SEIZURE | HP_FOCAL_MOTOR_SEIZURE | HP_FOCAL_MOTOR_SEIZURE | 17/1243 | 105/23056 | 0.1619048 | 3.003118 | 4.910898 | 0.0000447 | 0.0014457 | 0.0012705 | CHRNB2/MYT1L/SCN1A/KIF1A/SATB1/CACNA1D/GABRG2/DLL1/RELN/CHRNA2/KCNQ3/STXBP1/GRIN1/BRSK2/TCF4/ATP1A3/CACNG2 | 17 |
| GOBP_REGULATION_OF_DENDRITE_EXTENSION | GOBP_REGULATION_OF_DENDRITE_EXTENSION | GOBP_REGULATION_OF_DENDRITE_EXTENSION | 8/1243 | 26/23056 | 0.3076923 | 5.707284 | 5.732849 | 0.0000456 | 0.0014641 | 0.0012867 | BCL11A/CXCR4/RIMS1/RASAL1/SYT4/UNC13A/SYT3/CACNG7 | 8 |
| GOBP_SYNAPTIC_VESICLE_MEMBRANE_ORGANIZATION | GOBP_SYNAPTIC_VESICLE_MEMBRANE_ORGANIZATION | GOBP_SYNAPTIC_VESICLE_MEMBRANE_ORGANIZATION | 8/1243 | 26/23056 | 0.3076923 | 5.707284 | 5.732849 | 0.0000456 | 0.0014641 | 0.0012867 | CPLX1/CPLX2/STXBP1/CPLX3/STX1B/RAB3A/SNAP25/SYP | 8 |
| HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 46/1243 | 461/23056 | 0.0997831 | 1.850844 | 4.405087 | 0.0000457 | 0.0014661 | 0.0012884 | SYT11/ATP1B1/PGBD5/NRXN1/KIF5C/SELENOP/TUBB2A/TUBB2B/SOX4/CD24/RUNDC3B/CNTNAP2/ENPP2/TMOD1/SORBS1/CDKN1C/MAPK8IP1/GAL/TUBA1A/SLC4A8/PMEL/RNFT2/ZNF10/CCNA1/KCTD12/DHRS2/HSPA2/CALM1/ACSBG1/ABAT/DNAH3/SMPD3/MAPT/PPM1E/TUBB4A/NCAN/RTN2/SNAP25/MAFB/MAGEB2/SYN1/SSX3/NAP1L3/BEX4/L1CAM/TKTL1 | 46 |
| GOBP_SENSORY_ORGAN_MORPHOGENESIS | GOBP_SENSORY_ORGAN_MORPHOGENESIS | GOBP_SENSORY_ORGAN_MORPHOGENESIS | 31/1243 | 266/23056 | 0.1165414 | 2.161687 | 4.549025 | 0.0000468 | 0.0014951 | 0.0013139 | OLFM3/PROX1/SOX11/SIX3/MEIS1/FRZB/CRYGB/GATA2/PROM1/CHRNA9/LHFPL5/TFAP2B/DLL1/TWIST1/EYA1/CALB1/NTRK2/ROR2/CDH23/TH/USH1C/NECTIN1/FOXN4/ATP8A2/GSC/DIO3/STRC/BCL2/MAFB/BMP7/RS1 | 31 |
| HP_OCULOGYRIC_CRISIS | HP_OCULOGYRIC_CRISIS | HP_OCULOGYRIC_CRISIS | 11/1243 | 49/23056 | 0.2244898 | 4.163988 | 5.292529 | 0.0000469 | 0.0014951 | 0.0013139 | MYT1L/KIF1A/DLL1/DDC/STXBP1/GRIN1/DNAJC12/BRSK2/TH/TCF4/CACNG2 | 11 |
| HP_EEG_WITH_ABNORMALLY_SLOW_FREQUENCIES | HP_EEG_WITH_ABNORMALLY_SLOW_FREQUENCIES | HP_EEG_WITH_ABNORMALLY_SLOW_FREQUENCIES | 14/1243 | 76/23056 | 0.1842105 | 3.416861 | 5.037834 | 0.0000484 | 0.0015407 | 0.0013540 | SCN3A/SCN1A/SLC6A1/FGF12/GABRG2/ACTL6B/NTRK2/STXBP1/CACNA1B/CELF2/SLC1A2/GABRA5/MAPT/NEXMIF | 14 |
| REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 17/1243 | 106/23056 | 0.1603774 | 2.974787 | 4.864546 | 0.0000507 | 0.0016067 | 0.0014120 | SLC8A1/SLC38A3/SLC16A10/SLC24A2/SLC1A2/SLC4A8/SLC6A15/SLC17A8/SLC8A3/CALM1/SLC25A29/SLC4A1/SLC1A6/SLC8A2/SLC32A1/SLC38A5/SLC7A3 | 17 |
| MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | 13/1243 | 67/23056 | 0.1940299 | 3.598996 | 5.085614 | 0.0000509 | 0.0016099 | 0.0014148 | IGFBP2/SATB1/ATP8A1/SFRP2/STMN4/ELAVL2/GARNL3/PLXDC2/SCN3B/CKMT1A/ABAT/SBK1/BEX2 | 13 |
| GOBP_CARDIAC_MUSCLE_CONTRACTION | GOBP_CARDIAC_MUSCLE_CONTRACTION | GOBP_CARDIAC_MUSCLE_CONTRACTION | 20/1243 | 138/23056 | 0.1449275 | 2.688213 | 4.748309 | 0.0000515 | 0.0016246 | 0.0014277 | NPPA/PDE4B/ATP1B1/ADORA1/RYR2/SLC8A1/CXCR4/SCN1A/SCN5A/CACNA1D/FGF12/ANK2/SCN4B/SCN3B/KCNJ8/NOS1/CALM1/CHGA/DSC2/HRC | 20 |
| GOBP_CELL_FATE_SPECIFICATION | GOBP_CELL_FATE_SPECIFICATION | GOBP_CELL_FATE_SPECIFICATION | 16/1243 | 96/23056 | 0.1666667 | 3.091445 | 4.901812 | 0.0000518 | 0.0016293 | 0.0014318 | MYT1L/FEV/SOX2/SFRP2/ISL1/POU3F2/DLL1/EYA1/NODAL/TBX10/HOXC10/ASCL1/GSC/TBX4/EYA2/TBX22 | 16 |
| HP_ABNORMAL_AGGRESSIVE_IMPULSIVE_OR_VIOLENT_BEHAVIOR | HP_ABNORMAL_AGGRESSIVE_IMPULSIVE_OR_VIOLENT_BEHAVIOR | HP_ABNORMAL_AGGRESSIVE_IMPULSIVE_OR_VIOLENT_BEHAVIOR | 38/1243 | 357/23056 | 0.1064426 | 1.974368 | 4.429089 | 0.0000526 | 0.0016513 | 0.0014512 | GABRD/PRKCZ/SLC6A17/NTRK1/NFASC/MYT1L/SOX11/DPYSL5/KIF5C/SCN1A/UNC80/ABCA12/KIF1A/UROC1/SOX4/DLL1/CNTNAP2/KCNQ3/STXBP1/GRIN1/BRSK2/PDE2A/PAH/CUX2/SLITRK1/FGF14/MAGEL2/GABRB3/VAMP2/MAPT/ASXL3/TCF4/ATP1A3/CACNG2/SYN1/NEXMIF/PAK3/GRIA3 | 38 |
| HP_LIMITED_KNEE_EXTENSION | HP_LIMITED_KNEE_EXTENSION | HP_LIMITED_KNEE_EXTENSION | 7/1243 | 20/23056 | 0.3500000 | 6.492035 | 5.865502 | 0.0000542 | 0.0016980 | 0.0014922 | GABRD/DPYSL5/SCN1A/ADGRV1/GABRG2/STXBP1/STX1B | 7 |
| GOBP_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 21/1243 | 150/23056 | 0.1400000 | 2.596814 | 4.683665 | 0.0000568 | 0.0017731 | 0.0015583 | ELAVL4/LRRC7/PLPPR5/NTRK1/ALK/PACSIN1/CNR1/FUT9/FYN/GPC2/RELN/NTRK2/ROR2/CNTN1/CUX2/ATP8A2/RIT2/BMP7/PLA2G3/ZDHHC15/PAK3 | 21 |
| GOCC_CALCIUM_CHANNEL_COMPLEX | GOCC_CALCIUM_CHANNEL_COMPLEX | GOCC_CALCIUM_CHANNEL_COMPLEX | 13/1243 | 68/23056 | 0.1911765 | 3.546070 | 5.019201 | 0.0000598 | 0.0018641 | 0.0016382 | PDE4B/RYR2/CACNA2D2/CACNA1D/CACNA1B/AKAP6/HSPA2/CALM1/CACNG4/CACNG1/CACNG7/CACNG2/CACNA1F | 13 |
| WP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS | WP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS | WP_SPLICING_FACTOR_NOVA_REGULATED_SYNAPTIC_PROTEINS | 10/1243 | 42/23056 | 0.2380952 | 4.416351 | 5.289949 | 0.0000604 | 0.0018782 | 0.0016506 | PRKCZ/RAP1GAP/NTNG1/CADM3/CHL1/GABRG2/GRIK2/GRIN1/MAPK4/KCNJ6 | 10 |
| GOBP_GAMMA_AMINOBUTYRIC_ACID_SIGNALING_PATHWAY | GOBP_GAMMA_AMINOBUTYRIC_ACID_SIGNALING_PATHWAY | GOBP_GAMMA_AMINOBUTYRIC_ACID_SIGNALING_PATHWAY | 8/1243 | 27/23056 | 0.2962963 | 5.495903 | 5.579839 | 0.0000617 | 0.0019118 | 0.0016801 | PLCL2/GABRG1/GABRG2/GABRR2/GABRB3/GABRA5/GABRG3/SHISA7 | 8 |
| HP_RETINAL_DEGENERATION | HP_RETINAL_DEGENERATION | HP_RETINAL_DEGENERATION | 31/1243 | 270/23056 | 0.1148148 | 2.129662 | 4.457147 | 0.0000621 | 0.0019197 | 0.0016871 | ABCA4/NTNG1/CFHR3/MYT1L/APOB/DPYSL5/SCN3A/SATB1/ARL6/FGF12/PROM1/GABRG2/GUCA1A/RIMS1/ACTL6B/RP1L1/NTRK2/STXBP1/CACNA1B/CELF2/CDHR1/SLC1A2/GRIA4/GRK1/GABRA5/CLN6/CNGB1/GUCY2D/PRCD/LAMA1/RS1 | 31 |
| GOBP_MEMBRANE_FUSION | GOBP_MEMBRANE_FUSION | GOBP_MEMBRANE_FUSION | 22/1243 | 163/23056 | 0.1349693 | 2.503502 | 4.598401 | 0.0000670 | 0.0020664 | 0.0018160 | VAV3/SYT11/OTOF/DYSF/ROPN1B/CPLX1/CPLX2/RIMS1/STXBP1/MYMK/SYT13/SYT7/RAB39A/STXBP6/SERPINA5/CPLX3/STX1B/DOC2B/VAMP2/SYT4/RAB3A/SNAP25 | 22 |
| HP_PRENATAL_MOVEMENT_ABNORMALITY | HP_PRENATAL_MOVEMENT_ABNORMALITY | HP_PRENATAL_MOVEMENT_ABNORMALITY | 26/1243 | 210/23056 | 0.1238095 | 2.296502 | 4.505451 | 0.0000683 | 0.0020993 | 0.0018449 | PAX7/NFASC/DPYSL5/PPM1B/KIF5C/SCN3A/CHRNA1/CHRND/FGF12/CPLX1/MEGF10/GABRG2/ACTL6B/NTRK2/STXBP1/MYMK/CACNA1B/CELF2/CHAT/SLC1A2/CNTN1/ASCL1/MAGEL2/GABRA5/SNAP25/NEXMIF | 26 |
| GOBP_DETECTION_OF_MECHANICAL_STIMULUS | GOBP_DETECTION_OF_MECHANICAL_STIMULUS | GOBP_DETECTION_OF_MECHANICAL_STIMULUS | 11/1243 | 51/23056 | 0.2156863 | 4.000694 | 5.121016 | 0.0000694 | 0.0021137 | 0.0018576 | NTRK1/CXCR4/SCN1A/CHRNA9/KIT/ADGRV1/LHFPL5/FYN/STRC/TMC2/PKDREJ | 11 |
| GOBP_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT | 11/1243 | 51/23056 | 0.2156863 | 4.000694 | 5.121016 | 0.0000694 | 0.0021137 | 0.0018576 | NPPA/ATP1B1/ADORA1/RGS7/ANK2/ADRA2A/KCNC1/GAL/KCNC2/AKAP6/EDN3 | 11 |
| GOBP_SYNAPTIC_TRANSMISSION_GABAERGIC | GOBP_SYNAPTIC_TRANSMISSION_GABAERGIC | GOBP_SYNAPTIC_TRANSMISSION_GABAERGIC | 11/1243 | 51/23056 | 0.2156863 | 4.000694 | 5.121016 | 0.0000694 | 0.0021137 | 0.0018576 | ADORA1/SLC6A1/PLCL2/SLITRK3/GABRG1/GABRG2/CNR1/STXBP1/DRD2/GABRA5/GABRG3 | 11 |
| HP_ANOSMIA | HP_ANOSMIA | HP_ANOSMIA | 11/1243 | 51/23056 | 0.2156863 | 4.000694 | 5.121016 | 0.0000694 | 0.0021137 | 0.0018576 | SIX3/IL17RD/PROK2/SOX2/FGF17/ANK1/TAC3/ARNT2/DCC/PROKR2/ANOS1 | 11 |
| GOBP_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | GOBP_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | GOBP_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | 12/1243 | 60/23056 | 0.2000000 | 3.709735 | 5.016914 | 0.0000721 | 0.0021893 | 0.0019240 | ATP1B1/RYR2/SLC8A1/SCN5A/CACNA1D/ANK2/SCN4B/SCN3B/CALM1/DSC2/ATP1A3/HRC | 12 |
| GOBP_ORGANELLE_MEMBRANE_FUSION | GOBP_ORGANELLE_MEMBRANE_FUSION | GOBP_ORGANELLE_MEMBRANE_FUSION | 17/1243 | 109/23056 | 0.1559633 | 2.892912 | 4.728694 | 0.0000727 | 0.0022030 | 0.0019361 | VAV3/SYT11/DYSF/CPLX1/CPLX2/STXBP1/SYT13/SYT7/RAB39A/STXBP6/CPLX3/STX1B/DOC2B/VAMP2/SYT4/RAB3A/SNAP25 | 17 |
| GOBP_NEURONAL_ACTION_POTENTIAL | GOBP_NEURONAL_ACTION_POTENTIAL | GOBP_NEURONAL_ACTION_POTENTIAL | 9/1243 | 35/23056 | 0.2571429 | 4.769659 | 5.327634 | 0.0000738 | 0.0022297 | 0.0019595 | GPR88/SCN3A/SCN1A/SCN7A/CHRNA1/SCN5A/FGF12/GRIK2/P2RX3 | 9 |
| GOCC_CYTOPLASMIC_REGION | GOCC_CYTOPLASMIC_REGION | GOCC_CYTOPLASMIC_REGION | 30/1243 | 260/23056 | 0.1153846 | 2.140231 | 4.413781 | 0.0000740 | 0.0022297 | 0.0019595 | CFAP74/PRKCZ/HPCA/GRIK3/RIMS3/AGBL4/DRC1/KIF5C/MAP2/KIF1A/BSN/ERC2/ARL6/TMEM108/DCDC2/RIMS1/GRIK2/OPRM1/RP1L1/INSC/KIF5A/CCDC63/DNAH3/MAPT/TUBB4A/CAMSAP3/UNC13A/PPFIA3/CFAP61/DCX | 30 |
| HP_INTERICTAL_EEG_ABNORMALITY | HP_INTERICTAL_EEG_ABNORMALITY | HP_INTERICTAL_EEG_ABNORMALITY | 33/1243 | 298/23056 | 0.1107383 | 2.054048 | 4.371815 | 0.0000746 | 0.0022445 | 0.0019725 | GABRD/CHRNB2/SCN3A/SCN1A/KIF1A/SLC6A1/SATB1/FGF12/CPLX1/ADGRV1/GABRG2/TUBB2A/PHACTR1/GRIK2/ACTL6B/RELN/CHRNA2/KCNQ3/NTRK2/STXBP1/CACNA1B/CELF2/CHAT/KCNJ11/SLC1A2/PDE2A/CUX2/GABRB3/GABRA5/STX1B/SNAP25/NEXMIF/DCX | 33 |
| GOBP_SENSORY_PERCEPTION_OF_PAIN | GOBP_SENSORY_PERCEPTION_OF_PAIN | GOBP_SENSORY_PERCEPTION_OF_PAIN | 16/1243 | 99/23056 | 0.1616162 | 2.997765 | 4.755158 | 0.0000759 | 0.0022662 | 0.0019916 | OPRD1/CHRNB2/NTRK1/ADORA1/CXCR4/SCN1A/HOXD1/PROK2/CNR1/FYN/VIP/OPRM1/P2RX3/SCN3B/P2RX7/ACE | 16 |
| GOBP_SPINAL_CORD_DEVELOPMENT | GOBP_SPINAL_CORD_DEVELOPMENT | GOBP_SPINAL_CORD_DEVELOPMENT | 16/1243 | 99/23056 | 0.1616162 | 2.997765 | 4.755158 | 0.0000759 | 0.0022662 | 0.0019916 | TAL1/PROX1/SOX11/GATA2/ISL1/SOX4/DLL1/ACTL6B/RELN/DRGX/SLIT1/VSTM5/HOXC10/ASCL1/FOXN4/DCC | 16 |
| SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | 16/1243 | 99/23056 | 0.1616162 | 2.997765 | 4.755158 | 0.0000759 | 0.0022662 | 0.0019916 | KIF5C/CPB1/ESR1/MGAM/DUSP4/FBP1/ATRNL1/GFRA1/FAIM2/SLC4A8/PAH/ASCL1/SERPINA5/ABAT/PTPRT/INPP5J | 16 |
| HP_ABNORMAL_DARK_ADAPTED_ELECTRORETINOGRAM | HP_ABNORMAL_DARK_ADAPTED_ELECTRORETINOGRAM | HP_ABNORMAL_DARK_ADAPTED_ELECTRORETINOGRAM | 7/1243 | 21/23056 | 0.3333333 | 6.182891 | 5.672154 | 0.0000776 | 0.0023032 | 0.0020241 | ABCA4/CFHR3/PDE6B/GRM6/GRK1/RS1/CACNA1F | 7 |
| WP_NICOTINE_EFFECT_ON_DOPAMINERGIC_NEURONS | WP_NICOTINE_EFFECT_ON_DOPAMINERGIC_NEURONS | WP_NICOTINE_EFFECT_ON_DOPAMINERGIC_NEURONS | 7/1243 | 21/23056 | 0.3333333 | 6.182891 | 5.672154 | 0.0000776 | 0.0023032 | 0.0020241 | CHRNB2/KCNK3/DDC/KCNK9/TH/DRD2/CHRNA3 | 7 |
| GOCC_9PLUS0_NON_MOTILE_CILIUM | GOCC_9PLUS0_NON_MOTILE_CILIUM | GOCC_9PLUS0_NON_MOTILE_CILIUM | 19/1243 | 131/23056 | 0.1450382 | 2.690266 | 4.631230 | 0.0000777 | 0.0023032 | 0.0020241 | ABCA4/RD3/PCARE/MYRIP/PDE6B/PROM1/GUCA1A/PKHD1/RP1L1/CDHR1/OPN4/USH1C/SHANK2/ATP8A2/GRK1/CNGB1/GUCY2D/PRCD/CACNA1F | 19 |
| GOBP_FOREBRAIN_DEVELOPMENT | GOBP_FOREBRAIN_DEVELOPMENT | GOBP_FOREBRAIN_DEVELOPMENT | 39/1243 | 377/23056 | 0.1034483 | 1.918828 | 4.293915 | 0.0000785 | 0.0023218 | 0.0020404 | CHD5/HTR6/ELAVL4/CHRNB2/TNR/CNTN2/PROX1/ALK/SLC8A1/SIX3/CXCR4/CDK5R2/SCN5A/GATA2/TMEM108/SOX2/ISL1/PHACTR1/POU3F2/FYN/NPY/RELN/CNTNAP2/PAX5/NTRK2/NRG3/SLIT1/TH/KCNC1/SLC1A2/DRD2/KCNC2/ASCL1/GSC/RTN4RL1/CDK5R1/SSTR2/SLC32A1/NR0B1 | 39 |
| GOBP_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_SOUND | GOBP_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_SOUND | GOBP_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_SOUND | 6/1243 | 15/23056 | 0.4000000 | 7.419469 | 5.936828 | 0.0000797 | 0.0023320 | 0.0020495 | CHRNA9/KIT/ADGRV1/LHFPL5/STRC/TMC2 | 6 |
| GOBP_G_PROTEIN_COUPLED_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | GOBP_G_PROTEIN_COUPLED_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | GOBP_G_PROTEIN_COUPLED_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | 6/1243 | 15/23056 | 0.4000000 | 7.419469 | 5.936828 | 0.0000797 | 0.0023320 | 0.0020495 | GRIK3/GRM2/GRM6/GRM4/GRM8/GRM5 | 6 |
| GOBP_REGULATION_OF_PRESYNAPTIC_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_PRESYNAPTIC_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_PRESYNAPTIC_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | 6/1243 | 15/23056 | 0.4000000 | 7.419469 | 5.936828 | 0.0000797 | 0.0023320 | 0.0020495 | ADORA1/ATP2B2/SCGN/CNR1/CALB1/ATP2B3 | 6 |
| GOCC_PARALLEL_FIBER_TO_PURKINJE_CELL_SYNAPSE | GOCC_PARALLEL_FIBER_TO_PURKINJE_CELL_SYNAPSE | GOCC_PARALLEL_FIBER_TO_PURKINJE_CELL_SYNAPSE | 6/1243 | 15/23056 | 0.4000000 | 7.419469 | 5.936828 | 0.0000797 | 0.0023320 | 0.0020495 | KCNJ9/CNTN6/ATP2B2/CBLN1/GRIA3/ATP2B3 | 6 |
| HALLMARK_KRAS_SIGNALING_DN | HALLMARK_KRAS_SIGNALING_DN | HALLMARK_KRAS_SIGNALING_DN | 25/1243 | 200/23056 | 0.1250000 | 2.318584 | 4.470778 | 0.0000799 | 0.0023334 | 0.0020506 | RYR2/RSAD2/SLC30A3/CD207/IGFBP2/ARPP21/SLC38A3/CPB1/PDE6B/BMPR1B/SELENOP/SNCB/TFAP2B/SLC29A3/CALCB/NOS1/CCNA1/NGB/RGS11/CACNG1/DCC/KCNN1/ATP4A/YPEL1/CACNA1F | 25 |
| GOBP_NEURAL_RETINA_DEVELOPMENT | GOBP_NEURAL_RETINA_DEVELOPMENT | GOBP_NEURAL_RETINA_DEVELOPMENT | 13/1243 | 70/23056 | 0.1857143 | 3.444754 | 4.890045 | 0.0000819 | 0.0023603 | 0.0020743 | SIX3/ATP2B2/PROM1/POU4F2/TFAP2B/CALB1/NTRK2/USH1C/SLC17A8/FOXN4/ATP8A2/DIO3/RS1 | 13 |
| GOBP_REGULATION_OF_ORGANIC_ACID_TRANSPORT | GOBP_REGULATION_OF_ORGANIC_ACID_TRANSPORT | GOBP_REGULATION_OF_ORGANIC_ACID_TRANSPORT | 13/1243 | 70/23056 | 0.1857143 | 3.444754 | 4.890045 | 0.0000819 | 0.0023603 | 0.0020743 | ADORA1/SLC6A1/SLC38A3/GRM2/ACSL1/SYK/STXBP1/P2RX7/IRS2/ABAT/SYT4/HRH3/PLA2G3 | 13 |
| HP_ABNORMAL_MORPHOLOGY_OF_THE_LIMBIC_SYSTEM | HP_ABNORMAL_MORPHOLOGY_OF_THE_LIMBIC_SYSTEM | HP_ABNORMAL_MORPHOLOGY_OF_THE_LIMBIC_SYSTEM | 13/1243 | 70/23056 | 0.1857143 | 3.444754 | 4.890045 | 0.0000819 | 0.0023603 | 0.0020743 | MYT1L/DPYSL5/SCN1A/KIF1A/CPLX1/GABRG2/DLL1/STXBP1/GRIN1/BRSK2/DCC/TCF4/CACNG2 | 13 |
| HP_POOR_MOTOR_COORDINATION | HP_POOR_MOTOR_COORDINATION | HP_POOR_MOTOR_COORDINATION | 13/1243 | 70/23056 | 0.1857143 | 3.444754 | 4.890045 | 0.0000819 | 0.0023603 | 0.0020743 | GABRD/CXCR4/SCN1A/BMPR1B/ADGRV1/GABRG2/STXBP1/DLK1/RTL1/MAGEL2/STX1B/DCC/DCX | 13 |
| HUANG_DASATINIB_RESISTANCE_DN | HUANG_DASATINIB_RESISTANCE_DN | HUANG_DASATINIB_RESISTANCE_DN | 13/1243 | 70/23056 | 0.1857143 | 3.444754 | 4.890045 | 0.0000819 | 0.0023603 | 0.0020743 | GREB1/IGFBP2/ICA1/TPD52/SLC1A2/CHRM1/CALM1/DEGS2/SBK1/MAPT/HID1/PREX1/ABCG1 | 13 |
| GOCC_INTEGRAL_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | GOCC_INTEGRAL_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | GOCC_INTEGRAL_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | 8/1243 | 28/23056 | 0.2857143 | 5.299621 | 5.434273 | 0.0000823 | 0.0023603 | 0.0020743 | OPRD1/SLC6A17/SLC30A3/TMEM163/SLC17A8/SYT4/SLC32A1/SYP | 8 |
| REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | 8/1243 | 28/23056 | 0.2857143 | 5.299621 | 5.434273 | 0.0000823 | 0.0023603 | 0.0020743 | SLC8A1/ATP2B2/P2RX3/P2RX7/SLC8A3/CALM1/SLC8A2/ATP2B3 | 8 |
| GOBP_REGULATION_OF_CELL_DEVELOPMENT | GOBP_REGULATION_OF_CELL_DEVELOPMENT | GOBP_REGULATION_OF_CELL_DEVELOPMENT | 48/1243 | 500/23056 | 0.0960000 | 1.780673 | 4.212921 | 0.0000824 | 0.0023603 | 0.0020743 | NGF/TNR/SOX11/BCL11A/CXCR4/FRZB/MAP2/HES6/SEMA5B/FAIM/KIT/POU4F2/TLR2/FSTL4/TTBK1/OPRM1/DLL1/FERD3L/RELN/DMTN/NTRK2/BRINP1/NODAL/SLIT1/NEURL1/RASSF10/MAP6/GRM5/DRD2/ASCL1/CUX2/SLITRK1/SPINT1/ISLR2/RNF112/CDK5R1/MAPT/ACE/SYT4/DCC/BCL2/DLL3/PREX1/BMP7/CHODL/TIAM1/PAK3/L1CAM | 48 |
| GOBP_EYE_MORPHOGENESIS | GOBP_EYE_MORPHOGENESIS | GOBP_EYE_MORPHOGENESIS | 21/1243 | 154/23056 | 0.1363636 | 2.529364 | 4.545640 | 0.0000837 | 0.0023920 | 0.0021021 | OLFM3/PROX1/SOX11/SIX3/MEIS1/CRYGB/PROM1/TFAP2B/DLL1/TWIST1/CALB1/NTRK2/TH/USH1C/NECTIN1/FOXN4/ATP8A2/DIO3/BCL2/BMP7/RS1 | 21 |
| HP_ATTENTION_DEFICIT_HYPERACTIVITY_DISORDER | HP_ATTENTION_DEFICIT_HYPERACTIVITY_DISORDER | HP_ATTENTION_DEFICIT_HYPERACTIVITY_DISORDER | 38/1243 | 365/23056 | 0.1041096 | 1.931095 | 4.280297 | 0.0000844 | 0.0024057 | 0.0021142 | NTNG1/CHRNB2/MYT1L/DPYSL5/SIX3/SCN3A/SCN1A/SLC6A1/SATB1/FGF12/GABRG2/TUBB2B/DLL1/ACTL6B/CHRNA2/NTRK2/STXBP1/CACNA1B/CELF2/DNAJC12/NODAL/CDKN1C/SLC1A2/GRIA4/PAH/SLITRK1/MAGEL2/GABRB3/GABRA5/CHRNA7/MCTP2/PRKCG/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/RAB39B | 38 |
| DURAND_STROMA_S_UP | DURAND_STROMA_S_UP | DURAND_STROMA_S_UP | 33/1243 | 300/23056 | 0.1100000 | 2.040354 | 4.329664 | 0.0000850 | 0.0024177 | 0.0021248 | CYP2J2/PEAR1/LGALSL/NCKAP5/GALNT13/PDE1A/B3GALNT1/PDGFRA/RNF150/SFRP2/SELENOP/BACH2/THSD7A/PRUNE2/ROR2/ZNF618/CDKN1C/LRRC4C/CHST1/AKAP6/DUOXA1/CRABP1/RTN4RL1/ONECUT2/CCN5/SULF2/TSPAN7/SYN1/ZDHHC15/RPS6KA6/CAPN6/LONRF3/GRIA3 | 33 |
| GOBP_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 26/1243 | 213/23056 | 0.1220657 | 2.264157 | 4.424607 | 0.0000866 | 0.0024544 | 0.0021570 | NPPA/ATP1B1/RYR2/RGS7/COX17/KLF15/ANK2/POU4F2/ACSL1/RELN/SORBS1/KCNC1/SLC1A2/GAL/FGF19/KCNC2/NOS1/P2RX7/IRS2/AKAP6/HSPA2/CALM1/CACNG4/EDN3/CACNG2/NLGN3 | 26 |
| GOBP_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 25/1243 | 201/23056 | 0.1243781 | 2.307049 | 4.442830 | 0.0000867 | 0.0024544 | 0.0021570 | CLDN19/CHRNB2/NTRK1/NRXN1/LHFPL4/CLSTN2/SLITRK3/TLR2/ADGRB3/CNTNAP2/DMTN/NTRK2/SLIT1/VSTM5/NECTIN1/CUX2/SLITRK1/SLITRK5/ST8SIA2/CBLN1/ACE/CAMSAP3/SYNDIG1/GPM6B/NLGN3 | 25 |
| GOBP_ASSOCIATIVE_LEARNING | GOBP_ASSOCIATIVE_LEARNING | GOBP_ASSOCIATIVE_LEARNING | 14/1243 | 80/23056 | 0.1750000 | 3.246018 | 4.803761 | 0.0000870 | 0.0024567 | 0.0021590 | ELAVL4/CHRNB2/TNR/SLC6A1/KIT/RELN/DBH/GRIN1/SHANK2/DRD2/GABRA5/SHANK1/BRSK1/SNAP25 | 14 |
| GOBP_REGULATION_OF_POSTSYNAPTIC_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_POSTSYNAPTIC_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_POSTSYNAPTIC_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | 5/1243 | 10/23056 | 0.5000000 | 9.274336 | 6.247350 | 0.0000906 | 0.0025493 | 0.0022404 | SLC8A1/ATP2B2/CALB1/GRM5/SLC8A2 | 5 |
| GOCC_PRESYNAPTIC_CYTOSKELETON | GOCC_PRESYNAPTIC_CYTOSKELETON | GOCC_PRESYNAPTIC_CYTOSKELETON | 5/1243 | 10/23056 | 0.5000000 | 9.274336 | 6.247350 | 0.0000906 | 0.0025493 | 0.0022404 | RIMS3/BSN/ERC2/RIMS1/SEPTIN3 | 5 |
| GOCC_CELL_PROJECTION_MEMBRANE | GOCC_CELL_PROJECTION_MEMBRANE | GOCC_CELL_PROJECTION_MEMBRANE | 36/1243 | 340/23056 | 0.1058824 | 1.963977 | 4.274651 | 0.0000911 | 0.0025570 | 0.0022472 | OPRD1/HPCA/THEM4/ADORA1/ATP2B2/GAP43/PDE6B/PROM1/GABRG1/ADGRV1/PSD2/GABRG2/CDHR2/UNC5A/PACSIN1/OPRM1/CNTNAP2/DMTN/SH2D3C/CDHR1/PSD/KCNC1/SLC1A2/SHANK2/DRD2/KCNC2/GABRA5/GABRG3/CNGB1/GUCY2D/MAPT/ACE/PRCD/KCNC3/SHISA7/LAMP5 | 36 |
| GOCC_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | GOCC_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | GOCC_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | 10/1243 | 44/23056 | 0.2272727 | 4.215607 | 5.096507 | 0.0000924 | 0.0025864 | 0.0022730 | PDE4B/CACNA2D2/CACNA1D/CACNA1B/HSPA2/CACNG4/CACNG1/CACNG7/CACNG2/CACNA1F | 10 |
| GOBP_DENDRITE_EXTENSION | GOBP_DENDRITE_EXTENSION | GOBP_DENDRITE_EXTENSION | 9/1243 | 36/23056 | 0.2500000 | 4.637168 | 5.213416 | 0.0000937 | 0.0025936 | 0.0022793 | BCL11A/CXCR4/TMEM108/RIMS1/RASAL1/SYT4/UNC13A/SYT3/CACNG7 | 9 |
| GOBP_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL | GOBP_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL | GOBP_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL | 9/1243 | 36/23056 | 0.2500000 | 4.637168 | 5.213416 | 0.0000937 | 0.0025936 | 0.0022793 | SLC8A1/SCN3A/SCN1A/SCN7A/SCN5A/CACNA1D/ANK2/SCN4B/SCN3B | 9 |
| GOBP_PROTEIN_LOCALIZATION_TO_POSTSYNAPSE | GOBP_PROTEIN_LOCALIZATION_TO_POSTSYNAPSE | GOBP_PROTEIN_LOCALIZATION_TO_POSTSYNAPSE | 9/1243 | 36/23056 | 0.2500000 | 4.637168 | 5.213416 | 0.0000937 | 0.0025936 | 0.0022793 | PRKCZ/GRIP2/CPLX1/NSG1/STX1B/CACNG7/SNAP25/CACNG2/ZDHHC15 | 9 |
| HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP | HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP | HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP | 9/1243 | 36/23056 | 0.2500000 | 4.637168 | 5.213416 | 0.0000937 | 0.0025936 | 0.0022793 | NSG1/PPP2R2C/PNMA2/OLFM1/BRSK2/RTN1/ELAVL3/PCSK1N/DCX | 9 |
| KANG_GLIS3_TARGETS | KANG_GLIS3_TARGETS | KANG_GLIS3_TARGETS | 9/1243 | 36/23056 | 0.2500000 | 4.637168 | 5.213416 | 0.0000937 | 0.0025936 | 0.0022793 | RIMS3/FRZB/ISL1/SCGN/SYT13/CHGA/GJD2/PPY/MAFB | 9 |
| WP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING | WP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING | WP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING | 20/1243 | 144/23056 | 0.1388889 | 2.576204 | 4.529213 | 0.0000946 | 0.0026107 | 0.0022944 | GRIK3/NGF/SLC38A3/GRM2/GRM4/GRIK2/GRM8/GRIN1/SLC1A2/GRM5/GRIA4/IL10RA/GRIK4/NOS1/CALM1/BCL2/SLC1A6/PRKCG/SLC38A5/GRIA3 | 20 |
| GOBP_AMINE_METABOLIC_PROCESS | GOBP_AMINE_METABOLIC_PROCESS | GOBP_AMINE_METABOLIC_PROCESS | 18/1243 | 122/23056 | 0.1475410 | 2.736689 | 4.591162 | 0.0000949 | 0.0026138 | 0.0022970 | OAZ3/CHRNB2/HAAO/HAND2/SNCB/NPY/DDC/DBH/TH/DRD2/PAH/KL/GCH1/ABAT/ATCAY/ITGB2/ASMT/MAOB | 18 |
| GOMF_SYNTAXIN_BINDING | GOMF_SYNTAXIN_BINDING | GOMF_SYNTAXIN_BINDING | 13/1243 | 71/23056 | 0.1830986 | 3.396236 | 4.827218 | 0.0000954 | 0.0026163 | 0.0022992 | STXBP5L/CPLX1/CPLX2/STXBP1/SYT8/SYT7/CPLX3/DOC2B/VAMP2/UNC13A/SYT3/SYT5/SNAP25 | 13 |
| MEBARKI_HCC_PROGENITOR_WNT_DN_BLOCKED_BY_FZD8CRD | MEBARKI_HCC_PROGENITOR_WNT_DN_BLOCKED_BY_FZD8CRD | MEBARKI_HCC_PROGENITOR_WNT_DN_BLOCKED_BY_FZD8CRD | 13/1243 | 71/23056 | 0.1830986 | 3.396236 | 4.827218 | 0.0000954 | 0.0026163 | 0.0022992 | EPHA10/PAIP2B/JAKMIP2/SPINK5/TRMT9B/FGD3/RALGPS1/ADARB2/FGD4/ABCD2/TTC6/GCH1/FBXO27 | 13 |
| GOBP_NEGATIVE_REGULATION_OF_SECRETION | GOBP_NEGATIVE_REGULATION_OF_SECRETION | GOBP_NEGATIVE_REGULATION_OF_SECRETION | 22/1243 | 167/23056 | 0.1317365 | 2.443538 | 4.469237 | 0.0000966 | 0.0026409 | 0.0023209 | PTGER3/SYT11/ADORA1/RSAD2/VSNL1/KLF7/CD200/CNR1/OPRM1/ADRA2A/KCNJ11/SPI1/DRD2/STXBP6/CHGA/ABAT/SRCIN1/ACE/SYT4/HRH3/MAOB/IL13RA2 | 22 |
| GOBP_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 36/1243 | 341/23056 | 0.1055718 | 1.958218 | 4.255449 | 0.0000967 | 0.0026409 | 0.0023209 | ELAVL4/LRRC7/PLPPR5/NGF/NTRK1/ALK/ZMYND10/KIT/POU4F2/PACSIN1/CNR1/FUT9/FYN/GPC2/RELN/ENPP2/NTRK2/ROR2/NEURL1/MAP6/CNTN1/CUX2/P2RX7/ATP8A2/SLITRK1/ISLR2/CARMIL2/MAPT/RIT2/BMP7/CHODL/TIAM1/PLA2G3/ZDHHC15/PAK3/L1CAM | 36 |
| HP_GASTROESOPHAGEAL_REFLUX | HP_GASTROESOPHAGEAL_REFLUX | HP_GASTROESOPHAGEAL_REFLUX | 43/1243 | 435/23056 | 0.0988506 | 1.833547 | 4.189664 | 0.0000988 | 0.0026920 | 0.0023658 | GABRD/PRKCZ/MYT1L/SIX3/NRXN1/SCN3A/KIF1A/SATB1/FGF12/CPLX1/GABRG2/DLL1/TWIST1/DDC/ACTL6B/SFTPC/KCNQ3/NTRK2/STXBP1/MYMK/ADAMTSL2/GRIN1/CACNA1B/CELF2/CHAT/NODAL/MUC5B/BRSK2/SLC6A5/SLC1A2/ASCL1/NOS1/MAGEL2/GABRA5/CHRNA3/ARNT2/TBX4/ASXL3/TCF4/SNAP25/CACNG2/SHROOM4/NEXMIF | 43 |
| GOCC_ANCHORED_COMPONENT_OF_PLASMA_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_PLASMA_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_PLASMA_MEMBRANE | 12/1243 | 62/23056 | 0.1935484 | 3.590066 | 4.874834 | 0.0001007 | 0.0027378 | 0.0024061 | IGSF21/NTNG1/RHBG/CNTN2/CNTN6/PKHD1/CD24/GPC2/CNTN1/GPC5/CPLX3/RTN4RL1 | 12 |
| GOBP_CALCIUM_MEDIATED_SIGNALING | GOBP_CALCIUM_MEDIATED_SIGNALING | GOBP_CALCIUM_MEDIATED_SIGNALING | 25/1243 | 203/23056 | 0.1231527 | 2.284319 | 4.387426 | 0.0001018 | 0.0027597 | 0.0024253 | HPCA/ATP1B1/RYR2/CHRM3/SLC8A1/CXCR4/AGTR1/ANK2/DEFB1/DMTN/SYK/GRIN1/C10orf71/P2RX3/GRM5/KSR2/P2RX7/AKAP6/CALM1/MCTP2/MAPT/RIT2/P2RY11/SLC8A2/HRC | 25 |
| HP_LIMB_MYOCLONUS | HP_LIMB_MYOCLONUS | HP_LIMB_MYOCLONUS | 8/1243 | 29/23056 | 0.2758621 | 5.116875 | 5.295518 | 0.0001083 | 0.0028902 | 0.0025400 | NTNG1/CPLX1/GABRG2/KCNQ3/STXBP1/DRD2/GABRB3/MAPT | 8 |
| REACTOME_ACTIVATION_OF_AMPK_DOWNSTREAM_OF_NMDARS | REACTOME_ACTIVATION_OF_AMPK_DOWNSTREAM_OF_NMDARS | REACTOME_ACTIVATION_OF_AMPK_DOWNSTREAM_OF_NMDARS | 8/1243 | 29/23056 | 0.2758621 | 5.116875 | 5.295518 | 0.0001083 | 0.0028902 | 0.0025400 | TUBA3E/TUBB2A/TUBB2B/TUBA1A/TUBA3C/CALM1/MAPT/TUBB4A | 8 |
| GOBP_CATECHOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | GOBP_CATECHOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | GOBP_CATECHOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | 7/1243 | 22/23056 | 0.3181818 | 5.901850 | 5.490945 | 0.0001085 | 0.0028902 | 0.0025400 | HAND2/DDC/DBH/TH/PAH/KL/GCH1 | 7 |
| GOBP_LIGAND_GATED_ION_CHANNEL_SIGNALING_PATHWAY | GOBP_LIGAND_GATED_ION_CHANNEL_SIGNALING_PATHWAY | GOBP_LIGAND_GATED_ION_CHANNEL_SIGNALING_PATHWAY | 7/1243 | 22/23056 | 0.3181818 | 5.901850 | 5.490945 | 0.0001085 | 0.0028902 | 0.0025400 | GRIK3/GRIK2/GRIN1/GRIA4/GRIK4/CDK5R1/GRIA3 | 7 |
| GOBP_REGULATION_OF_VESICLE_FUSION | GOBP_REGULATION_OF_VESICLE_FUSION | GOBP_REGULATION_OF_VESICLE_FUSION | 7/1243 | 22/23056 | 0.3181818 | 5.901850 | 5.490945 | 0.0001085 | 0.0028902 | 0.0025400 | CPLX1/CPLX2/STXBP1/CPLX3/DOC2B/SYT4/RAB3A | 7 |
| GOBP_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT | 7/1243 | 22/23056 | 0.3181818 | 5.901850 | 5.490945 | 0.0001085 | 0.0028902 | 0.0025400 | NTRK1/SOX11/HAND2/GFRA3/SOX4/TFAP2B/ASCL1 | 7 |
| GOBP_VESICLE_FUSION_TO_PLASMA_MEMBRANE | GOBP_VESICLE_FUSION_TO_PLASMA_MEMBRANE | GOBP_VESICLE_FUSION_TO_PLASMA_MEMBRANE | 7/1243 | 22/23056 | 0.3181818 | 5.901850 | 5.490945 | 0.0001085 | 0.0028902 | 0.0025400 | CPLX1/CPLX2/STXBP1/CPLX3/STX1B/RAB3A/SNAP25 | 7 |
| GOMF_AMINO_ACID_CATION_SYMPORTER_ACTIVITY | GOMF_AMINO_ACID_CATION_SYMPORTER_ACTIVITY | GOMF_AMINO_ACID_CATION_SYMPORTER_ACTIVITY | 7/1243 | 22/23056 | 0.3181818 | 5.901850 | 5.490945 | 0.0001085 | 0.0028902 | 0.0025400 | SLC6A11/SLC6A1/SLC6A5/SLC1A2/SLC6A15/SLC1A6/SLC32A1 | 7 |
| MIKKELSEN_MEF_LCP_WITH_H3K27ME3 | MIKKELSEN_MEF_LCP_WITH_H3K27ME3 | MIKKELSEN_MEF_LCP_WITH_H3K27ME3 | 13/1243 | 72/23056 | 0.1805556 | 3.349066 | 4.765506 | 0.0001107 | 0.0029440 | 0.0025873 | RD3/CD207/PLCD4/CDHR2/CNTNAP2/ADAMTSL2/ZNF385C/PPY/SLC4A1/BTBD17/CDH7/CCM2L/ANOS1 | 13 |
| HP_EEG_WITH_MULTIFOCAL_SLOW_ACTIVITY | HP_EEG_WITH_MULTIFOCAL_SLOW_ACTIVITY | HP_EEG_WITH_MULTIFOCAL_SLOW_ACTIVITY | 10/1243 | 45/23056 | 0.2222222 | 4.121927 | 5.004051 | 0.0001131 | 0.0030001 | 0.0026366 | SCN3A/FGF12/GABRG2/ACTL6B/NTRK2/STXBP1/CACNA1B/CELF2/SLC1A2/GABRA5 | 10 |
| MCLACHLAN_DENTAL_CARIES_DN | MCLACHLAN_DENTAL_CARIES_DN | MCLACHLAN_DENTAL_CARIES_DN | 14/1243 | 82/23056 | 0.1707317 | 3.166847 | 4.692207 | 0.0001147 | 0.0030327 | 0.0026653 | NRXN1/KIF5C/GAP43/KIT/SPOCK3/TUBB2B/CD24/CALB1/NEBL/MPPED2/DIO3/CRABP1/TIAM1/NAP1L3 | 14 |
| GOBP_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | GOBP_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | GOBP_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | 22/1243 | 169/23056 | 0.1301775 | 2.414620 | 4.406047 | 0.0001153 | 0.0030327 | 0.0026653 | CHD5/TAL1/AGBL4/ELAVL4/CHRNB2/CNTN2/PROX1/MAP2/GATA2/ISL1/SOX4/NPY/NTRK2/DRD2/FAIM2/HOXC10/ASCL1/FOXN4/CBLN1/MAPT/DCC/NOVA2 | 22 |
| GOBP_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | 22/1243 | 169/23056 | 0.1301775 | 2.414620 | 4.406047 | 0.0001153 | 0.0030327 | 0.0026653 | NGF/PROX1/CXCR4/POU4F2/RIMS1/POU3F2/DLL1/RAG2/DRD2/RASAL1/ATP8A2/AKAP6/DIO3/ISLR2/MAPT/SYT4/BCL2/UNC13A/SYT3/CACNG7/SASH3/L1CAM | 22 |
| GOCC_ANCHORED_COMPONENT_OF_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_MEMBRANE | 22/1243 | 169/23056 | 0.1301775 | 2.414620 | 4.406047 | 0.0001153 | 0.0030327 | 0.0026653 | IGSF21/NTNG1/RHBG/CNTN2/CNTN6/CNTN4/CNTN3/ENPP6/RAB3C/GFRA3/PKHD1/CD24/GPC2/GFRA1/CNTN1/GPC5/CPLX3/RTN4RL1/RAB3A/LYPD5/SYN1/XPNPEP2 | 22 |
| HP_ABNORMAL_EYELID_PHYSIOLOGY | HP_ABNORMAL_EYELID_PHYSIOLOGY | HP_ABNORMAL_EYELID_PHYSIOLOGY | 9/1243 | 37/23056 | 0.2432432 | 4.511839 | 5.103319 | 0.0001180 | 0.0030953 | 0.0027202 | HPCA/CPLX1/TWIST1/DDC/CLCN1/MAPT/TUBB4A/MAFB/SALL4 | 9 |
| GOBP_ACIDIC_AMINO_ACID_TRANSPORT | GOBP_ACIDIC_AMINO_ACID_TRANSPORT | GOBP_ACIDIC_AMINO_ACID_TRANSPORT | 12/1243 | 63/23056 | 0.1904762 | 3.533081 | 4.805979 | 0.0001184 | 0.0031001 | 0.0027244 | ADORA1/SLC6A1/GRM2/NTRK2/STXBP1/SLC1A2/SLC17A8/P2RX7/ABAT/SYT4/SLC1A6/HRH3 | 12 |
| HP_POOR_FINE_MOTOR_COORDINATION | HP_POOR_FINE_MOTOR_COORDINATION | HP_POOR_FINE_MOTOR_COORDINATION | 11/1243 | 54/23056 | 0.2037037 | 3.778433 | 4.879491 | 0.0001203 | 0.0031292 | 0.0027500 | GABRD/CXCR4/SCN1A/ADGRV1/GABRG2/STXBP1/DLK1/RTL1/MAGEL2/STX1B/DCC | 11 |
| REACTOME_ION_HOMEOSTASIS | REACTOME_ION_HOMEOSTASIS | REACTOME_ION_HOMEOSTASIS | 11/1243 | 54/23056 | 0.2037037 | 3.778433 | 4.879491 | 0.0001203 | 0.0031292 | 0.0027500 | ATP1B1/RYR2/SLC8A1/ATP2B2/KCNJ11/NOS1/SLC8A3/CALM1/ATP1A3/SLC8A2/ATP2B3 | 11 |
| WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION | WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION | WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION | 11/1243 | 54/23056 | 0.2037037 | 3.778433 | 4.879491 | 0.0001203 | 0.0031292 | 0.0027500 | PDE4B/PDE1A/ADCY5/PDE6B/GUCY1A1/GRIN1/PDE2A/DRD2/NOS1/CHRFAM7A/CHRNA7 | 11 |
| GOCC_PRESYNAPTIC_ACTIVE_ZONE_CYTOPLASMIC_COMPONENT | GOCC_PRESYNAPTIC_ACTIVE_ZONE_CYTOPLASMIC_COMPONENT | GOCC_PRESYNAPTIC_ACTIVE_ZONE_CYTOPLASMIC_COMPONENT | 6/1243 | 16/23056 | 0.3750000 | 6.955752 | 5.688736 | 0.0001216 | 0.0031378 | 0.0027576 | RIMS3/BSN/ERC2/RIMS1/UNC13A/PPFIA3 | 6 |
| GOMF_AMINO_ACID_SODIUM_SYMPORTER_ACTIVITY | GOMF_AMINO_ACID_SODIUM_SYMPORTER_ACTIVITY | GOMF_AMINO_ACID_SODIUM_SYMPORTER_ACTIVITY | 6/1243 | 16/23056 | 0.3750000 | 6.955752 | 5.688736 | 0.0001216 | 0.0031378 | 0.0027576 | SLC6A11/SLC6A1/SLC6A5/SLC1A2/SLC6A15/SLC1A6 | 6 |
| HP_EEG_WITH_FOCAL_SPIKE_WAVES | HP_EEG_WITH_FOCAL_SPIKE_WAVES | HP_EEG_WITH_FOCAL_SPIKE_WAVES | 6/1243 | 16/23056 | 0.3750000 | 6.955752 | 5.688736 | 0.0001216 | 0.0031378 | 0.0027576 | SCN1A/SLC6A1/SATB1/CPLX1/GABRG2/NEXMIF | 6 |
| WP_BIOGENIC_AMINE_SYNTHESIS | WP_BIOGENIC_AMINE_SYNTHESIS | WP_BIOGENIC_AMINE_SYNTHESIS | 6/1243 | 16/23056 | 0.3750000 | 6.955752 | 5.688736 | 0.0001216 | 0.0031378 | 0.0027576 | DDC/DBH/CHAT/TH/PAH/ASMT | 6 |
| GOMF_STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON | GOMF_STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON | GOMF_STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON | 16/1243 | 103/23056 | 0.1553398 | 2.881347 | 4.568023 | 0.0001232 | 0.0031641 | 0.0027807 | ADD2/CTNNA2/TUBA3E/VILL/BFSP2/ANK2/TUBB2A/TUBB2B/ACTL6B/ANK1/EPB41L4B/INA/TUBA1A/TUBA3C/TUBB4A/NEFH | 16 |
| HP_BRADYKINESIA | HP_BRADYKINESIA | HP_BRADYKINESIA | 16/1243 | 103/23056 | 0.1553398 | 2.881347 | 4.568023 | 0.0001232 | 0.0031641 | 0.0027807 | GABRD/DNAJC6/SCN1A/ADGRV1/GABRG2/STXBP1/DNAJC12/TH/GCH1/STX1B/JPH3/MAPT/ATP1A3/KCNC3/JAM2/RAB39B | 16 |
| GOBP_SYNAPTIC_VESICLE_RECYCLING | GOBP_SYNAPTIC_VESICLE_RECYCLING | GOBP_SYNAPTIC_VESICLE_RECYCLING | 13/1243 | 73/23056 | 0.1780822 | 3.303188 | 4.704873 | 0.0001282 | 0.0032851 | 0.0028871 | DNAJC6/SNCB/PACSIN1/SNAP91/SYT8/SYT7/STX1B/VAMP2/RAB3A/SYT5/SYP/NLGN3/NLGN4Y | 13 |
| HP_PHENOTYPIC_VARIABILITY | HP_PHENOTYPIC_VARIABILITY | HP_PHENOTYPIC_VARIABILITY | 40/1243 | 400/23056 | 0.1000000 | 1.854867 | 4.117158 | 0.0001333 | 0.0034089 | 0.0029958 | KCNK3/SIX3/SCN1A/CHRNA1/KIF1A/CACNA2D2/PROK2/FGF12/GUCY1A1/MEGF10/GABRG2/TUBB2A/TUBB2B/TWIST1/RELN/CHRNA2/EYA1/STXBP1/CDH23/TH/ANO5/GRIA4/CD3G/PTPRO/KIF5A/SMAD9/F7/GCH1/GABRB3/CHRNA7/STX1B/GUCY2D/LAMA1/DCC/TUBB4A/ATP1A3/PRKCG/PROKR2/NEFH/DCX | 40 |
| RODWELL_AGING_KIDNEY_DN | RODWELL_AGING_KIDNEY_DN | RODWELL_AGING_KIDNEY_DN | 20/1243 | 148/23056 | 0.1351351 | 2.506577 | 4.389238 | 0.0001387 | 0.0035394 | 0.0031105 | FNDC5/PTGER3/ESRRG/KNG1/FAM153A/ARFGEF3/THSD7A/TPD52/FRMD3/PLPPR1/NEBL/MPPED2/SHANK2/BTBD11/CRABP1/SLC4A1/BMP7/TSPAN7/ZNF711/GPRASP1 | 20 |
| GOBP_LONG_TERM_SYNAPTIC_DEPRESSION | GOBP_LONG_TERM_SYNAPTIC_DEPRESSION | GOBP_LONG_TERM_SYNAPTIC_DEPRESSION | 8/1243 | 30/23056 | 0.2666667 | 4.946313 | 5.163014 | 0.0001407 | 0.0035698 | 0.0031372 | ADORA1/GRID2IP/SLC24A2/STXBP1/SORCS3/SHANK2/CBLN1/MAPT | 8 |
| GOBP_NEURON_FATE_SPECIFICATION | GOBP_NEURON_FATE_SPECIFICATION | GOBP_NEURON_FATE_SPECIFICATION | 8/1243 | 30/23056 | 0.2666667 | 4.946313 | 5.163014 | 0.0001407 | 0.0035698 | 0.0031372 | MYT1L/FEV/ISL1/POU3F2/DLL1/EYA1/HOXC10/ASCL1 | 8 |
| WP_DOPAMINERGIC_NEUROGENESIS | WP_DOPAMINERGIC_NEUROGENESIS | WP_DOPAMINERGIC_NEUROGENESIS | 8/1243 | 30/23056 | 0.2666667 | 4.946313 | 5.163014 | 0.0001407 | 0.0035698 | 0.0031372 | SOX2/NEUROG2/DDC/EN2/ALDH1A1/TH/CDKN1C/ASCL1 | 8 |
| GOBP_POSTSYNAPTIC_SIGNAL_TRANSDUCTION | GOBP_POSTSYNAPTIC_SIGNAL_TRANSDUCTION | GOBP_POSTSYNAPTIC_SIGNAL_TRANSDUCTION | 9/1243 | 38/23056 | 0.2368421 | 4.393107 | 4.997076 | 0.0001472 | 0.0037265 | 0.0032749 | CHRNB2/RGS8/CHRM3/OPRM1/CHRM1/CHRNA7/CHRNA3/CDK5R1/HRH3 | 9 |
| GOBP_ORGANIC_ANION_TRANSPORT | GOBP_ORGANIC_ANION_TRANSPORT | GOBP_ORGANIC_ANION_TRANSPORT | 37/1243 | 362/23056 | 0.1022099 | 1.895859 | 4.101085 | 0.0001512 | 0.0038191 | 0.0033563 | SLC6A17/ADORA1/AGXT/SLC6A11/SLC6A1/SLC38A3/GRM2/SLC10A4/SLC35D3/ABCB4/NTRK2/SYK/STXBP1/SLC6A5/SLC1A2/SLC22A6/SLC22A24/SLC22A10/FGF19/DRD2/SLCO1B1/SLC4A8/SLC6A15/SLC17A8/PLA2G1B/P2RX7/SLC25A29/ABAT/SLC4A1/ACE/SYT4/SLC1A6/SLC32A1/HRH3/PLA2G3/SLC38A5/SLC7A3 | 37 |
| GOBP_REGULATION_OF_HEART_RATE | GOBP_REGULATION_OF_HEART_RATE | GOBP_REGULATION_OF_HEART_RATE | 16/1243 | 105/23056 | 0.1523810 | 2.826464 | 4.477808 | 0.0001553 | 0.0039132 | 0.0034390 | NPPA/RYR2/SLC8A1/SCN5A/CACNA1D/ANK2/ISL1/DRD2/SCN4B/SCN3B/GCH1/CALM1/KCNH6/DSC2/HRC/EDN3 | 16 |
| GOBP_SA_NODE_CELL_TO_ATRIAL_CARDIAC_MUSCLE_CELL_COMMUNICATION | GOBP_SA_NODE_CELL_TO_ATRIAL_CARDIAC_MUSCLE_CELL_COMMUNICATION | GOBP_SA_NODE_CELL_TO_ATRIAL_CARDIAC_MUSCLE_CELL_COMMUNICATION | 5/1243 | 11/23056 | 0.4545455 | 8.431215 | 5.884753 | 0.0001588 | 0.0039697 | 0.0034887 | RYR2/SCN5A/CACNA1D/ANK2/SCN3B | 5 |
| GOCC_ANCHORED_COMPONENT_OF_SYNAPTIC_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_SYNAPTIC_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_SYNAPTIC_MEMBRANE | 5/1243 | 11/23056 | 0.4545455 | 8.431215 | 5.884753 | 0.0001588 | 0.0039697 | 0.0034887 | NTNG1/CNTN2/CNTN6/CNTN1/CPLX3 | 5 |
| HP_GENERALIZED_CEREBRAL_ATROPHY_HYPOPLASIA | HP_GENERALIZED_CEREBRAL_ATROPHY_HYPOPLASIA | HP_GENERALIZED_CEREBRAL_ATROPHY_HYPOPLASIA | 5/1243 | 11/23056 | 0.4545455 | 8.431215 | 5.884753 | 0.0001588 | 0.0039697 | 0.0034887 | GABRD/SCN1A/ADGRV1/GABRG2/STX1B | 5 |
| REACTOME_SODIUM_CALCIUM_EXCHANGERS | REACTOME_SODIUM_CALCIUM_EXCHANGERS | REACTOME_SODIUM_CALCIUM_EXCHANGERS | 5/1243 | 11/23056 | 0.4545455 | 8.431215 | 5.884753 | 0.0001588 | 0.0039697 | 0.0034887 | SLC8A1/SLC24A2/SLC8A3/CALM1/SLC8A2 | 5 |
| JAEGER_METASTASIS_DN | JAEGER_METASTASIS_DN | JAEGER_METASTASIS_DN | 29/1243 | 259/23056 | 0.1119691 | 2.076878 | 4.160429 | 0.0001639 | 0.0040886 | 0.0035932 | CRYBG2/PLPPR4/IRF6/VSNL1/BCL11A/CD207/ABCA12/MST1R/CPA3/KIT/SPINK5/TFAP2B/CD24/MAP7/DEFB1/ENPP2/PRSS3/NTRK2/NEBL/CDHR1/TRIM29/TP53AIP1/EFS/CKMT1B/DUOX1/HLF/DSC2/DSC1/BMP7 | 29 |
| GOBP_LIPID_TRANSLOCATION | GOBP_LIPID_TRANSLOCATION | GOBP_LIPID_TRANSLOCATION | 11/1243 | 56/23056 | 0.1964286 | 3.643489 | 4.727898 | 0.0001695 | 0.0042200 | 0.0037086 | ABCA4/ABCA12/PLSCR5/ATP8A1/ABCB4/XKR5/P2RX7/ATP8A2/SLC4A1/XKR7/ABCG1 | 11 |
| MCCLUNG_COCAINE_REWARD_5D | MCCLUNG_COCAINE_REWARD_5D | MCCLUNG_COCAINE_REWARD_5D | 13/1243 | 75/23056 | 0.1733333 | 3.215103 | 4.586703 | 0.0001702 | 0.0042288 | 0.0037164 | PDE4B/OAZ3/ADORA1/ACTL6B/STXBP1/CELF2/PTPN5/GRIA4/STX1B/VAMP2/TUBB4A/TSPAN7/SYP | 13 |
| HP_UNSTEADY_GAIT | HP_UNSTEADY_GAIT | HP_UNSTEADY_GAIT | 21/1243 | 162/23056 | 0.1296296 | 2.404458 | 4.282188 | 0.0001733 | 0.0042974 | 0.0037767 | SYT14/SCN3A/SCN1A/KIF1A/SLC6A1/FGF12/GABRG2/ACTL6B/NTRK2/STXBP1/CACNA1B/CELF2/SLC1A2/FGD4/GABRA5/MAPT/DCC/MAST1/ATP1A3/NEXMIF/ATP2B3 | 21 |
| GOBP_POSITIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS | 6/1243 | 17/23056 | 0.3529412 | 6.546590 | 5.461088 | 0.0001794 | 0.0044219 | 0.0038861 | CDK5R2/STXBP1/SYT7/SCAMP5/DOC2B/SYT4 | 6 |
| GOCC_VOLTAGE_GATED_SODIUM_CHANNEL_COMPLEX | GOCC_VOLTAGE_GATED_SODIUM_CHANNEL_COMPLEX | GOCC_VOLTAGE_GATED_SODIUM_CHANNEL_COMPLEX | 6/1243 | 17/23056 | 0.3529412 | 6.546590 | 5.461088 | 0.0001794 | 0.0044219 | 0.0038861 | SCN3A/SCN1A/SCN7A/SCN5A/SCN4B/SCN3B | 6 |
| MEBARKI_HCC_PROGENITOR_WNT_DN_CTNNB1_INDEPENDENT | MEBARKI_HCC_PROGENITOR_WNT_DN_CTNNB1_INDEPENDENT | MEBARKI_HCC_PROGENITOR_WNT_DN_CTNNB1_INDEPENDENT | 6/1243 | 17/23056 | 0.3529412 | 6.546590 | 5.461088 | 0.0001794 | 0.0044219 | 0.0038861 | APOB/TRMT9B/FGD3/ABCD2/TTC6/GCH1 | 6 |
| HP_LIMITATION_OF_KNEE_MOBILITY | HP_LIMITATION_OF_KNEE_MOBILITY | HP_LIMITATION_OF_KNEE_MOBILITY | 8/1243 | 31/23056 | 0.2580645 | 4.786754 | 5.036265 | 0.0001808 | 0.0044463 | 0.0039075 | GABRD/DPYSL5/DYSF/SCN1A/ADGRV1/GABRG2/STXBP1/STX1B | 8 |
| GOBP_CELLULAR_COMPONENT_MAINTENANCE | GOBP_CELLULAR_COMPONENT_MAINTENANCE | GOBP_CELLULAR_COMPONENT_MAINTENANCE | 12/1243 | 66/23056 | 0.1818182 | 3.372486 | 4.607513 | 0.0001882 | 0.0046186 | 0.0040590 | BSN/ERC2/ADGRB3/FYN/MTSS1/SHANK2/CBLN1/PARD6A/C1QL1/CAMSAP3/RAB3A/CBLN4 | 12 |
| GOMF_ATPASE_COUPLED_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ATPASE_COUPLED_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ATPASE_COUPLED_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 16/1243 | 107/23056 | 0.1495327 | 2.773633 | 4.389694 | 0.0001943 | 0.0047604 | 0.0041835 | ABCA4/ATP1B1/ABCA12/ATP2B2/ATP13A4/ATP8A1/ABCB4/KCNJ11/KCNJ8/ABCD2/SLC4A8/SLC4A1/ATP4A/ATP1A3/ABCG1/ATP2B3 | 16 |
| GOBP_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE | GOBP_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE | GOBP_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE | 11/1243 | 57/23056 | 0.1929825 | 3.579568 | 4.654686 | 0.0001999 | 0.0048733 | 0.0042827 | PROX1/PROM1/TFAP2B/DLL1/CALB1/NTRK2/USH1C/FOXN4/ATP8A2/DIO3/RS1 | 11 |
| GOMF_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING | GOMF_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING | GOMF_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING | 11/1243 | 57/23056 | 0.1929825 | 3.579568 | 4.654686 | 0.0001999 | 0.0048733 | 0.0042827 | SYT11/DYSF/SYT8/SYT13/SYT7/RPH3A/MCTP2/DOC2B/SYT4/SYT3/SYT5 | 11 |
| GOBP_PHOTOTRANSDUCTION | GOBP_PHOTOTRANSDUCTION | GOBP_PHOTOTRANSDUCTION | 10/1243 | 48/23056 | 0.2083333 | 3.864307 | 4.741996 | 0.0002002 | 0.0048733 | 0.0042827 | ABCA4/GPR88/PDE6B/GUCA1A/SLC24A2/OPN4/GRK1/CNGB1/GUCY2D/RS1 | 10 |
| HP_DYSPHAGIA | HP_DYSPHAGIA | HP_DYSPHAGIA | 45/1243 | 477/23056 | 0.0943396 | 1.749875 | 3.950536 | 0.0002011 | 0.0048869 | 0.0042947 | GABRD/PRKCZ/PAX7/HPCA/NTRK1/IRF6/SYT14/MYT1L/DPYSL5/SIX3/DYSF/SCN3A/CHRNA1/CHRND/KIF1A/SATB1/PDGFRA/KIT/GUCY1A1/MEGF10/DLL1/RELN/CLCN1/KCNK9/STXBP1/MYMK/GRIN1/CHAT/NODAL/BRSK2/NECTIN1/KIF5A/NOS1/GCH1/CARMIL2/MAPT/TCF4/TUBB4A/ATP1A3/KCNC3/PRKCG/SNAP25/NEFH/CACNG2/DCX | 45 |
| GOBP_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | GOBP_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | GOBP_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | 28/1243 | 250/23056 | 0.1120000 | 2.077451 | 4.088872 | 0.0002097 | 0.0050860 | 0.0044697 | NPPA/PDE4B/ATP1B1/ADORA1/RYR2/CHRM3/SLC8A1/SCN5A/PROK2/KIT/ANK2/GUCY1A1/HAND2/KCNB2/MYMK/ADRA2A/NOS1/AKAP6/SLC8A3/CALM1/CHGA/CHRNA3/CHRNB4/ABAT/SSTR2/PVALEF/DSC2/HRC | 28 |
| GOBP_RESPONSE_TO_CATECHOLAMINE | GOBP_RESPONSE_TO_CATECHOLAMINE | GOBP_RESPONSE_TO_CATECHOLAMINE | 16/1243 | 108/23056 | 0.1481481 | 2.747952 | 4.346396 | 0.0002169 | 0.0052497 | 0.0046136 | HTR6/PDE4B/HCN3/RGS8/RYR2/CHRM3/ALK/ADCY5/NSG1/NSG2/HRH2/HTR1E/CHRM1/DRD2/HTR3A/HRH3 | 16 |
| MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED | MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED | MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED | 14/1243 | 87/23056 | 0.1609195 | 2.984844 | 4.427671 | 0.0002195 | 0.0053016 | 0.0046592 | TAL1/DNAJB8/PCDHB10/PCDHB11/NRSN1/SCGN/GRID2IP/GOLGA7B/FGF6/NOS1/PIWIL1/KCNH6/SSTR2/DCC | 14 |
| GOBP_RESPONSE_TO_MECHANICAL_STIMULUS | GOBP_RESPONSE_TO_MECHANICAL_STIMULUS | GOBP_RESPONSE_TO_MECHANICAL_STIMULUS | 24/1243 | 201/23056 | 0.1194030 | 2.214767 | 4.129151 | 0.0002231 | 0.0053432 | 0.0046957 | NPPA/NTRK1/RYR2/SLC8A1/NRXN1/CXCR4/SCN1A/IGFBP2/CHRNA9/KIT/ADGRV1/LHFPL5/FYN/CNTNAP2/KCNC1/P2RX3/NRXN2/PDE2A/DRD2/P2RX7/ATP8A2/STRC/TMC2/PKDREJ | 24 |
| GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 13/1243 | 77/23056 | 0.1688312 | 3.131594 | 4.472442 | 0.0002236 | 0.0053432 | 0.0046957 | ATP1B1/RYR2/SLC8A1/SCN1A/SCN5A/CACNA1D/FGF12/ANK2/SCN4B/SCN3B/KCNJ8/CALM1/DSC2 | 13 |
| GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION | 13/1243 | 77/23056 | 0.1688312 | 3.131594 | 4.472442 | 0.0002236 | 0.0053432 | 0.0046957 | NPPA/PDE4B/ATP1B1/ADORA1/RYR2/SLC8A1/SCN5A/ANK2/NOS1/CALM1/CHGA/DSC2/HRC | 13 |
| GOBP_POSITIVE_REGULATION_OF_AMINE_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_AMINE_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_AMINE_TRANSPORT | 9/1243 | 40/23056 | 0.2250000 | 4.173451 | 4.795207 | 0.0002241 | 0.0053432 | 0.0046957 | CHRNB2/SLC6A1/SLC38A3/VIP/STXBP1/DRD2/P2RX7/ABAT/SYT4 | 9 |
| GOBP_REGULATION_OF_AMINO_ACID_TRANSPORT | GOBP_REGULATION_OF_AMINO_ACID_TRANSPORT | GOBP_REGULATION_OF_AMINO_ACID_TRANSPORT | 9/1243 | 40/23056 | 0.2250000 | 4.173451 | 4.795207 | 0.0002241 | 0.0053432 | 0.0046957 | ADORA1/SLC6A1/SLC38A3/GRM2/STXBP1/P2RX7/ABAT/SYT4/HRH3 | 9 |
| WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION | WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION | WP_MBDNF_AND_PROBDNF_REGULATION_OF_GABA_NEUROTRANSMISSION | 9/1243 | 40/23056 | 0.2250000 | 4.173451 | 4.795207 | 0.0002241 | 0.0053432 | 0.0046957 | GABRD/PIK3R3/GABRG1/GABRG2/GABRP/NTRK2/GABRB3/GABRA5/GABRG3 | 9 |
| GOBP_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | GOBP_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | GOBP_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | 21/1243 | 165/23056 | 0.1272727 | 2.360740 | 4.187407 | 0.0002243 | 0.0053432 | 0.0046957 | RYR2/SLC8A1/ANK2/FYN/ADCYAP1R1/SLC24A2/GRIN1/P2RX3/DRD2/NOS1/PLA2G1B/P2RX7/JPH4/AKAP6/SLC8A3/CALM1/JPH3/BCL2/JSRP1/SLC8A2/HRC | 21 |
| HP_RIGIDITY | HP_RIGIDITY | HP_RIGIDITY | 23/1243 | 189/23056 | 0.1216931 | 2.257246 | 4.142924 | 0.0002260 | 0.0053742 | 0.0047230 | DNAJC6/SCN3A/SCN1A/ABCA12/FGF12/GABRG2/ACTL6B/NTRK2/STXBP1/CACNA1B/CELF2/TH/SLC6A5/SLC1A2/GCH1/GABRA5/JPH3/MAPT/TUBB4A/ATP1A3/PRKCG/JAM2/RAB39B | 23 |
| WP_MONOAMINE_TRANSPORT | WP_MONOAMINE_TRANSPORT | WP_MONOAMINE_TRANSPORT | 8/1243 | 32/23056 | 0.2500000 | 4.637168 | 4.914829 | 0.0002297 | 0.0054516 | 0.0047910 | SLC6A1/DBH/TH/TPH2/NOS1/SLC6A2/HRH3/SYN1 | 8 |
| HP_FOCAL_DYSTONIA | HP_FOCAL_DYSTONIA | HP_FOCAL_DYSTONIA | 15/1243 | 98/23056 | 0.1530612 | 2.839082 | 4.355196 | 0.0002346 | 0.0055556 | 0.0048824 | HPCA/COLEC11/CPLX1/TWIST1/DDC/TH/DRD2/GCH1/MAPT/TUBB4A/ATP1A3/KCNC3/PRKCG/MAFB/SALL4 | 15 |
| GOBP_NEUROMUSCULAR_PROCESS_CONTROLLING_BALANCE | GOBP_NEUROMUSCULAR_PROCESS_CONTROLLING_BALANCE | GOBP_NEUROMUSCULAR_PROCESS_CONTROLLING_BALANCE | 10/1243 | 49/23056 | 0.2040816 | 3.785443 | 4.659323 | 0.0002395 | 0.0056293 | 0.0049471 | GPR88/TNR/NRXN1/ADCY5/POU4F2/CDH23/USH1C/JPH4/JPH3/SHANK1 | 10 |
| GOBP_NEURON_RECOGNITION | GOBP_NEURON_RECOGNITION | GOBP_NEURON_RECOGNITION | 10/1243 | 49/23056 | 0.2040816 | 3.785443 | 4.659323 | 0.0002395 | 0.0056293 | 0.0049471 | CNTN2/CXCR4/CNTN6/CNTN4/GAP43/CNR1/CNTNAP2/DSCAML1/CDK5R1/VSTM2L | 10 |
| GOBP_PHOTORECEPTOR_CELL_DEVELOPMENT | GOBP_PHOTORECEPTOR_CELL_DEVELOPMENT | GOBP_PHOTORECEPTOR_CELL_DEVELOPMENT | 10/1243 | 49/23056 | 0.2040816 | 3.785443 | 4.659323 | 0.0002395 | 0.0056293 | 0.0049471 | OLFM3/PCARE/RP1L1/NTRK2/CDHR1/TH/USH1C/DIO3/CNGB1/DCX | 10 |
| HP_INTELLECTUAL_DISABILITY_MODERATE | HP_INTELLECTUAL_DISABILITY_MODERATE | HP_INTELLECTUAL_DISABILITY_MODERATE | 28/1243 | 252/23056 | 0.1111111 | 2.060964 | 4.042553 | 0.0002396 | 0.0056293 | 0.0049471 | MYT1L/SOX11/PPM1B/SCN1A/KIF1A/CPLX1/SOX4/GRIK2/DLL1/TWIST1/STXBP1/GRIN1/BRSK2/PDE2A/KIF5A/MAGEL2/CHRNA7/LAMA1/ASXL3/TCF4/CACNG2/TSPAN7/SYP/ZNF711/PAK3/GRIA3/L1CAM/RAB39B | 28 |
| REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER | REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER | REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER | 13/1243 | 78/23056 | 0.1666667 | 3.091445 | 4.416703 | 0.0002552 | 0.0059863 | 0.0052609 | PIK3R3/PDGFRA/KIT/NRG2/FYN/ESR1/FGF17/NRG3/PIK3AP1/FGF19/FGF6/KL/IRS2 | 13 |
| GOMF_LIGAND_GATED_ANION_CHANNEL_ACTIVITY | GOMF_LIGAND_GATED_ANION_CHANNEL_ACTIVITY | GOMF_LIGAND_GATED_ANION_CHANNEL_ACTIVITY | 6/1243 | 18/23056 | 0.3333333 | 6.182891 | 5.251053 | 0.0002569 | 0.0060140 | 0.0052853 | GABRG1/GLRA3/GABRG2/GABRB3/GABRA5/GABRG3 | 6 |
| GOBP_CELL_FATE_COMMITMENT | GOBP_CELL_FATE_COMMITMENT | GOBP_CELL_FATE_COMMITMENT | 29/1243 | 266/23056 | 0.1090226 | 2.022224 | 4.002903 | 0.0002587 | 0.0060327 | 0.0053017 | TAL1/PROX1/MYT1L/WNT10A/FEV/GAP43/GATA2/SOX2/SFRP2/ISL1/POU3F2/DLL1/NKX6-3/EYA1/ROR2/NODAL/RAG2/TBX10/DSCAML1/HOXC10/ASCL1/FOXN4/GSC/ONECUT1/TBX4/ONECUT2/BCL2/EYA2/TBX22 | 29 |
| GOMF_ACTIVE_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ACTIVE_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ACTIVE_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 29/1243 | 266/23056 | 0.1090226 | 2.022224 | 4.002903 | 0.0002587 | 0.0060327 | 0.0053017 | ATP1B1/SLC8A1/ATP2B2/SLC6A11/SLC6A1/ATP13A4/ATP8A1/SLC10A4/SLC18A1/SLC24A2/KCNJ11/SLC6A5/SLC1A2/SLC22A6/SLCO1B1/KCNJ8/SLC4A8/SLC6A15/SLC8A3/SLC6A2/SLC4A1/SLC1A6/ATP4A/ATP1A3/SLC8A2/COX4I2/SLC32A1/SLC37A1/ATP2B3 | 29 |
| GOBP_SYNAPTIC_VESICLE_MATURATION | GOBP_SYNAPTIC_VESICLE_MATURATION | GOBP_SYNAPTIC_VESICLE_MATURATION | 5/1243 | 12/23056 | 0.4166667 | 7.728614 | 5.565417 | 0.0002601 | 0.0060546 | 0.0053210 | STXBP1/UNC13A/RAB3A/SYP/ZDHHC15 | 5 |
| POOLA_INVASIVE_BREAST_CANCER_DN | POOLA_INVASIVE_BREAST_CANCER_DN | POOLA_INVASIVE_BREAST_CANCER_DN | 18/1243 | 132/23056 | 0.1363636 | 2.529364 | 4.206425 | 0.0002618 | 0.0060814 | 0.0053445 | FRZB/IGFBP2/CACNA1D/CPB1/NPY2R/ZDHHC11/MYB/ESR1/AZGP1/DNAJC12/GFRA1/MPPED2/DACH1/SERPINA5/CLMN/MAPT/WFDC2/EDN3 | 18 |
| GOBP_GLUTAMATE_SECRETION | GOBP_GLUTAMATE_SECRETION | GOBP_GLUTAMATE_SECRETION | 7/1243 | 25/23056 | 0.2800000 | 5.193628 | 5.007996 | 0.0002652 | 0.0061256 | 0.0053833 | ADORA1/GRM2/NTRK2/STXBP1/P2RX7/SYT4/HRH3 | 7 |
| GOMF_VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY | GOMF_VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY | 7/1243 | 25/23056 | 0.2800000 | 5.193628 | 5.007996 | 0.0002652 | 0.0061256 | 0.0053833 | HCN3/SCN3A/SCN1A/SCN7A/SCN5A/SCN4B/SCN3B | 7 |
| LA_MEN1_TARGETS | LA_MEN1_TARGETS | LA_MEN1_TARGETS | 7/1243 | 25/23056 | 0.2800000 | 5.193628 | 5.007996 | 0.0002652 | 0.0061256 | 0.0053833 | RGS16/PTER/SORBS1/CRABP1/BCL6B/TSPAN7/BEX2 | 7 |
| GOBP_ANATOMICAL_STRUCTURE_HOMEOSTASIS | GOBP_ANATOMICAL_STRUCTURE_HOMEOSTASIS | GOBP_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 33/1243 | 319/23056 | 0.1034483 | 1.918828 | 3.944787 | 0.0002696 | 0.0062154 | 0.0054622 | ABCA4/ADORA1/HAAO/CHRNA1/ABCA12/ATP2B2/GATA2/PROM1/CRACD/ADGRV1/SCGN/CNR1/IL20RA/AZGP1/RP1L1/SGCZ/CALB1/ALDH1A1/SYK/VSTM4/CDH23/CDHR1/USH1C/P2RX7/CCDC154/SLC6A2/CNGB1/MC4R/BCL2/SLC8A2/JAM2/SASH3/ATP2B3 | 33 |
| GOBP_AMINE_BIOSYNTHETIC_PROCESS | GOBP_AMINE_BIOSYNTHETIC_PROCESS | GOBP_AMINE_BIOSYNTHETIC_PROCESS | 9/1243 | 41/23056 | 0.2195122 | 4.071660 | 4.699157 | 0.0002735 | 0.0062935 | 0.0055309 | OAZ3/HAND2/DDC/DBH/TH/PAH/KL/GCH1/ASMT | 9 |
| GOBP_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS | GOBP_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS | GOBP_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS | 11/1243 | 59/23056 | 0.1864407 | 3.458227 | 4.513078 | 0.0002748 | 0.0063104 | 0.0055457 | VSNL1/KLF7/ABCA12/PTPRN/GPR27/ADCY5/GPLD1/RFX6/PTPRN2/ADRA2A/BRSK2 | 11 |
| GOBP_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 20/1243 | 156/23056 | 0.1282051 | 2.378035 | 4.122543 | 0.0002841 | 0.0065114 | 0.0057224 | NPPA/HPCA/PDE4B/ATP1B1/RYR2/SLC8A1/ANK2/FYN/ADRA2A/DRD2/NOS1/JPH4/AKAP6/HSPA2/CALM1/JPH3/CACNG1/JSRP1/HRC/TMC2 | 20 |
| GOBP_POSTSYNAPTIC_SPECIALIZATION_ORGANIZATION | GOBP_POSTSYNAPTIC_SPECIALIZATION_ORGANIZATION | GOBP_POSTSYNAPTIC_SPECIALIZATION_ORGANIZATION | 8/1243 | 33/23056 | 0.2424242 | 4.496648 | 4.798310 | 0.0002890 | 0.0066133 | 0.0058119 | NRXN1/GAP43/TMEM108/SLITRK3/RELN/NRXN2/SHANK2/CBLN1 | 8 |
| CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP | 13/1243 | 79/23056 | 0.1645570 | 3.052313 | 4.361852 | 0.0002907 | 0.0066252 | 0.0058224 | FNDC5/GPR88/HAAO/RAPGEF4/GLCCI1/ICA1/ABCB4/GARNL3/ADAMTS17/IGFALS/HAPLN4/MPPED1/MAGEB2 | 13 |
| KEGG_CARDIAC_MUSCLE_CONTRACTION | KEGG_CARDIAC_MUSCLE_CONTRACTION | KEGG_CARDIAC_MUSCLE_CONTRACTION | 13/1243 | 79/23056 | 0.1645570 | 3.052313 | 4.361852 | 0.0002907 | 0.0066252 | 0.0058224 | ATP1B1/RYR2/SLC8A1/CACNA2D2/CACNA1D/CACNG5/CACNG4/CACNG1/ATP1A3/CACNG7/COX4I2/CACNG2/CACNA1F | 13 |
| HP_EXCESSIVE_SALIVATION | HP_EXCESSIVE_SALIVATION | HP_EXCESSIVE_SALIVATION | 17/1243 | 122/23056 | 0.1393443 | 2.584651 | 4.189229 | 0.0002961 | 0.0067361 | 0.0059199 | NRXN1/SCN1A/SATB1/GABRG2/TUBB2B/STXBP1/TH/GCH1/DLK1/RTL1/ATP1A3/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/RAB39B | 17 |
| SERVITJA_ISLET_HNF1A_TARGETS_UP | SERVITJA_ISLET_HNF1A_TARGETS_UP | SERVITJA_ISLET_HNF1A_TARGETS_UP | 21/1243 | 169/23056 | 0.1242604 | 2.304865 | 4.064197 | 0.0003125 | 0.0070966 | 0.0062367 | DPT/CHL1/GAP43/STXBP5L/SOX2/CPLX1/PRKG2/GUCY1A1/NSG2/NRSN1/CNR1/VIP/ADCYAP1R1/DUSP26/ELAVL2/NEBL/PTPRO/SLC6A15/FGF14/CACNG5/ITGB2 | 21 |
| KEGG_GAP_JUNCTION | KEGG_GAP_JUNCTION | KEGG_GAP_JUNCTION | 14/1243 | 90/23056 | 0.1555556 | 2.885349 | 4.277901 | 0.0003156 | 0.0071544 | 0.0062875 | TUBA3E/ADCY5/PDGFRA/PRKG2/GUCY1A1/TUBB2A/TUBB2B/GRM5/DRD2/TUBA1A/TUBA3C/GJD2/TUBB4A/PRKCG | 14 |
| GOBP_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | GOBP_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | GOBP_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 45/1243 | 487/23056 | 0.0924025 | 1.713943 | 3.801302 | 0.0003179 | 0.0071932 | 0.0063215 | NPPA/KANK4/VAV3/NGF/TNR/ADORA1/CNTN2/CHRM3/SLC8A1/ADD2/MAP2/GRIP2/VILL/HCLS1/SEMA5B/AGTR1/KNG1/CRACD/POU4F2/GUCY1A1/FSTL4/HRH2/CDHR2/DMTN/DPYSL2/TMOD1/DBH/OLFM1/VSTM4/SLIT1/ADRA2A/USH1C/NOS1/P2RX7/GCH1/ISLR2/CARMIL2/CDK5R1/MAPT/ACE/DCC/EDN3/PAK3/L1CAM/TMSB4Y | 45 |
| GOBP_ANATOMICAL_STRUCTURE_MATURATION | GOBP_ANATOMICAL_STRUCTURE_MATURATION | GOBP_ANATOMICAL_STRUCTURE_MATURATION | 27/1243 | 244/23056 | 0.1106557 | 2.052517 | 3.945507 | 0.0003276 | 0.0073969 | 0.0065006 | EPHA8/TAL1/CNTN2/RHEX/SIX3/BCL11A/CDK5R2/FEV/ROPN1/ROPN1B/GATA2/BFSP2/SPINK5/ADGRB3/ACTL6B/CNTNAP2/DEFB1/CDKN1C/GAL/ASCL1/SRRM4/CCDC154/CNGB1/CDK5R1/C1QL1/BCL2/PLA2G3 | 27 |
| YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | 19/1243 | 146/23056 | 0.1301370 | 2.413868 | 4.091036 | 0.0003293 | 0.0074221 | 0.0065227 | AGBL4/PTGER3/ADD2/FRZB/BCHE/KNG1/NSG1/MYB/MAP7/RELN/SCARA5/NTRK2/NEBL/RIC3/RERG/TSPAN11/ST8SIA2/ARRDC4/BMP7 | 19 |
| GOBP_CHLORIDE_TRANSPORT | GOBP_CHLORIDE_TRANSPORT | GOBP_CHLORIDE_TRANSPORT | 16/1243 | 112/23056 | 0.1428571 | 2.649810 | 4.178005 | 0.0003315 | 0.0074472 | 0.0065448 | GABRD/SLC6A1/GABRG1/PRKG2/GLRA3/GABRG2/GABRP/GABRR2/CLCN1/ANO5/GRM5/SLC4A8/GABRB3/GABRA5/GABRG3/SLC4A1 | 16 |
| ZHAN_MULTIPLE_MYELOMA_MF_DN | ZHAN_MULTIPLE_MYELOMA_MF_DN | ZHAN_MULTIPLE_MYELOMA_MF_DN | 9/1243 | 42/23056 | 0.2142857 | 3.974715 | 4.606112 | 0.0003316 | 0.0074472 | 0.0065448 | SLC22A15/ESRRG/TMEM170B/GPLD1/GLCCI1/NRG3/PDZRN4/STXBP6/BRSK1 | 9 |
| GOCC_CELL_CELL_CONTACT_ZONE | GOCC_CELL_CELL_CONTACT_ZONE | GOCC_CELL_CELL_CONTACT_ZONE | 12/1243 | 70/23056 | 0.1714286 | 3.179772 | 4.360024 | 0.0003335 | 0.0074750 | 0.0065692 | AJAP1/ATP1B1/SLC8A1/SCN1A/SCN5A/ANK2/SCN4B/NECTIN1/AKAP6/DSC2/JAM2/TIAM1 | 12 |
| HP_ABNORMAL_HYPOTHALAMUS_PHYSIOLOGY | HP_ABNORMAL_HYPOTHALAMUS_PHYSIOLOGY | HP_ABNORMAL_HYPOTHALAMUS_PHYSIOLOGY | 10/1243 | 51/23056 | 0.1960784 | 3.636995 | 4.500323 | 0.0003376 | 0.0075490 | 0.0066342 | SIX3/IL17RD/PROK2/DLL1/FGF17/NODAL/MAGEL2/DCC/PROKR2/ANOS1 | 10 |
| HP_ABSENT_SPEECH | HP_ABSENT_SPEECH | HP_ABSENT_SPEECH | 33/1243 | 323/23056 | 0.1021672 | 1.895066 | 3.867125 | 0.0003380 | 0.0075490 | 0.0066342 | GABRD/PRKCZ/SLC6A17/KCNH1/SOX11/DPYSL5/SIX3/CTNNA2/KIF5C/SCN3A/SCN1A/UNC80/KIF1A/SATB1/FGF12/CPLX1/GABRG2/SOX4/DLL1/ACTL6B/CNTNAP2/NTRK2/STXBP1/GRIN1/CACNA1B/NODAL/SLC1A2/GRIA4/MAGEL2/ASXL3/TCF4/SHROOM4/NEXMIF | 33 |
| GOBP_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY | GOBP_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY | GOBP_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY | 7/1243 | 26/23056 | 0.2692308 | 4.993873 | 4.864010 | 0.0003461 | 0.0077019 | 0.0067687 | NOS1/JPH4/AKAP6/CALM1/JPH3/JSRP1/HRC | 7 |
| GOMF_SPECTRIN_BINDING | GOMF_SPECTRIN_BINDING | GOMF_SPECTRIN_BINDING | 7/1243 | 26/23056 | 0.2692308 | 4.993873 | 4.864010 | 0.0003461 | 0.0077019 | 0.0067687 | ADD2/PTPRN/ANK2/DMTN/ANK1/USH1C/CAMSAP3 | 7 |
| GOBP_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 31/1243 | 297/23056 | 0.1043771 | 1.936057 | 3.875826 | 0.0003490 | 0.0077510 | 0.0068118 | NGF/SOX11/CXCR4/FAIM/KIT/POU4F2/TLR2/TTBK1/OPRM1/RELN/DMTN/NTRK2/NEURL1/RASSF10/MAP6/GRM5/DRD2/ASCL1/CUX2/SLITRK1/SPINT1/ISLR2/RNF112/MAPT/ACE/BCL2/PREX1/CHODL/TIAM1/PAK3/L1CAM | 31 |
| GOBP_G_PROTEIN_COUPLED_ACETYLCHOLINE_RECEPTOR_SIGNALING_PATHWAY | GOBP_G_PROTEIN_COUPLED_ACETYLCHOLINE_RECEPTOR_SIGNALING_PATHWAY | GOBP_G_PROTEIN_COUPLED_ACETYLCHOLINE_RECEPTOR_SIGNALING_PATHWAY | 6/1243 | 19/23056 | 0.3157895 | 5.857475 | 5.056324 | 0.0003584 | 0.0078887 | 0.0069328 | RGS8/CHRM3/OPRM1/CHRM1/CDK5R1/HRH3 | 6 |
| GOBP_REGULATION_OF_GLUTAMATE_SECRETION | GOBP_REGULATION_OF_GLUTAMATE_SECRETION | GOBP_REGULATION_OF_GLUTAMATE_SECRETION | 6/1243 | 19/23056 | 0.3157895 | 5.857475 | 5.056324 | 0.0003584 | 0.0078887 | 0.0069328 | ADORA1/GRM2/STXBP1/P2RX7/SYT4/HRH3 | 6 |
| GOMF_IONOTROPIC_GLUTAMATE_RECEPTOR_ACTIVITY | GOMF_IONOTROPIC_GLUTAMATE_RECEPTOR_ACTIVITY | GOMF_IONOTROPIC_GLUTAMATE_RECEPTOR_ACTIVITY | 6/1243 | 19/23056 | 0.3157895 | 5.857475 | 5.056324 | 0.0003584 | 0.0078887 | 0.0069328 | GRIK3/GRIK2/GRIN1/GRIA4/GRIK4/GRIA3 | 6 |
| GOMF_RETINAL_BINDING | GOMF_RETINAL_BINDING | GOMF_RETINAL_BINDING | 6/1243 | 19/23056 | 0.3157895 | 5.857475 | 5.056324 | 0.0003584 | 0.0078887 | 0.0069328 | RBP7/ABCA4/RBP1/ADH4/OPN4/CRABP1 | 6 |
| REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | 6/1243 | 19/23056 | 0.3157895 | 5.857475 | 5.056324 | 0.0003584 | 0.0078887 | 0.0069328 | SLC6A11/SLC6A1/SLC18A1/SLC6A5/SLC6A15/SLC6A2 | 6 |
| WP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV | WP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV | WP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV | 8/1243 | 34/23056 | 0.2352941 | 4.364394 | 4.686355 | 0.0003603 | 0.0079150 | 0.0069559 | RYR2/NRXN1/GRIN1/NRXN2/RPH3A/NRXN3/SHANK1/NLGN3 | 8 |
| GOMF_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 39/1243 | 406/23056 | 0.0960591 | 1.781769 | 3.793742 | 0.0003636 | 0.0079747 | 0.0070083 | ABCA4/SLC6A17/ATP1B1/SLC8A1/ABCA12/ATP2B2/SLC6A11/SLC6A1/SLC38A3/ATP13A4/ATP8A1/SLC10A4/SLC16A10/SLC35D3/ABCB4/SLC18A1/SLC24A2/KCNJ11/SLC6A5/SLC1A2/SLC22A6/SLCO1B1/KCNJ8/ABCD2/SLC4A8/SLC6A15/SLC17A8/SLC8A3/SLC6A2/SLC4A1/SLC1A6/ATP4A/ATP1A3/SLC8A2/COX4I2/SLC32A1/ABCG1/SLC37A1/ATP2B3 | 39 |
| DELYS_THYROID_CANCER_DN | DELYS_THYROID_CANCER_DN | DELYS_THYROID_CANCER_DN | 26/1243 | 233/23056 | 0.1115880 | 2.069809 | 3.917944 | 0.0003676 | 0.0080464 | 0.0070714 | RAP1GAP/TAL1/DPT/RGS16/ESRRG/RYR2/TPO/PROM1/KIT/ZDHHC11/ELMO1/RELN/CPQ/ALDH1A1/ROR2/EPB41L4B/MPPED2/CLMN/CRABP1/HLF/BCL2/SYNDIG1/EYA2/EDN3/TSPAN7/CHRDL1 | 26 |
| DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | 34/1243 | 339/23056 | 0.1002950 | 1.860339 | 3.809380 | 0.0003892 | 0.0085037 | 0.0074733 | PGBD5/ALK/BCL11A/ARHGAP25/RAPGEF4/KLF7/SYN2/TAGLN3/ANK2/JAKMIP2/ELOVL2/TFAP2B/CNR1/MYB/ELMO1/VIPR2/DLGAP2/PAX5/GADD45G/PLPPR1/BRINP1/ADRA2A/NELL1/B3GAT1/C14orf132/ABAT/TEX14/CHST8/EYA2/EDN3/ABCG1/NR0B1/CAPN6/DCX | 34 |
| GOBP_CYTOSOLIC_CALCIUM_ION_TRANSPORT | GOBP_CYTOSOLIC_CALCIUM_ION_TRANSPORT | GOBP_CYTOSOLIC_CALCIUM_ION_TRANSPORT | 22/1243 | 184/23056 | 0.1195652 | 2.217776 | 3.958993 | 0.0003925 | 0.0085609 | 0.0075235 | RYR2/SLC8A1/ANK2/FYN/ADCYAP1R1/SLC24A2/GRIN1/P2RX3/DRD2/NOS1/PLA2G1B/P2RX7/JPH4/AKAP6/SLC8A3/CALM1/JPH3/BCL2/JSRP1/SLC8A2/HRC/ATP2B3 | 22 |
| GOBP_MEMBRANE_REPOLARIZATION | GOBP_MEMBRANE_REPOLARIZATION | GOBP_MEMBRANE_REPOLARIZATION | 10/1243 | 52/23056 | 0.1923077 | 3.567052 | 4.423797 | 0.0003980 | 0.0086365 | 0.0075899 | NPPA/ATP1B1/KCNH7/SCN5A/CACNA1D/ANK2/SCN4B/KCNJ8/AKAP6/KCNH6 | 10 |
| GOCC_CHLORIDE_CHANNEL_COMPLEX | GOCC_CHLORIDE_CHANNEL_COMPLEX | GOCC_CHLORIDE_CHANNEL_COMPLEX | 10/1243 | 52/23056 | 0.1923077 | 3.567052 | 4.423797 | 0.0003980 | 0.0086365 | 0.0075899 | GABRD/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/CLCN1/GABRB3/GABRA5/GABRG3 | 10 |
| GOBP_RESPONSE_TO_DOPAMINE | GOBP_RESPONSE_TO_DOPAMINE | GOBP_RESPONSE_TO_DOPAMINE | 14/1243 | 92/23056 | 0.1521739 | 2.822624 | 4.181457 | 0.0003981 | 0.0086365 | 0.0075899 | HTR6/HCN3/RGS8/CHRM3/ALK/ADCY5/NSG1/NSG2/HRH2/HTR1E/CHRM1/DRD2/HTR3A/HRH3 | 14 |
| GOBERT_CORE_OLIGODENDROCYTE_DIFFERENTIATION | GOBERT_CORE_OLIGODENDROCYTE_DIFFERENTIATION | GOBERT_CORE_OLIGODENDROCYTE_DIFFERENTIATION | 9/1243 | 43/23056 | 0.2093023 | 3.882280 | 4.515899 | 0.0003996 | 0.0086375 | 0.0075908 | UGT8/ENPP6/MAP7/ELMO1/SORBS1/DSCAML1/ABAT/PAK5/PAK3 | 9 |
| HP_EYELID_MYOCLONUS | HP_EYELID_MYOCLONUS | HP_EYELID_MYOCLONUS | 9/1243 | 43/23056 | 0.2093023 | 3.882280 | 4.515899 | 0.0003996 | 0.0086375 | 0.0075908 | MYT1L/KIF1A/SLC6A1/DLL1/STXBP1/GRIN1/BRSK2/TCF4/CACNG2 | 9 |
| GOBP_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | GOBP_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | GOBP_PERIPHERAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | 5/1243 | 13/23056 | 0.3846154 | 7.134105 | 5.280971 | 0.0004040 | 0.0086870 | 0.0076343 | HAND2/ISL1/NTRK2/ONECUT2/NEFH | 5 |
| GOBP_TRANS_SYNAPTIC_SIGNALING_MODULATING_SYNAPTIC_TRANSMISSION | GOBP_TRANS_SYNAPTIC_SIGNALING_MODULATING_SYNAPTIC_TRANSMISSION | GOBP_TRANS_SYNAPTIC_SIGNALING_MODULATING_SYNAPTIC_TRANSMISSION | 5/1243 | 13/23056 | 0.3846154 | 7.134105 | 5.280971 | 0.0004040 | 0.0086870 | 0.0076343 | GUCY1A1/CNR1/NTRK2/GRM5/SYT4 | 5 |
| GOMF_GABA_GATED_CHLORIDE_ION_CHANNEL_ACTIVITY | GOMF_GABA_GATED_CHLORIDE_ION_CHANNEL_ACTIVITY | GOMF_GABA_GATED_CHLORIDE_ION_CHANNEL_ACTIVITY | 5/1243 | 13/23056 | 0.3846154 | 7.134105 | 5.280971 | 0.0004040 | 0.0086870 | 0.0076343 | GABRG1/GABRG2/GABRB3/GABRA5/GABRG3 | 5 |
| GOBP_PHOTORECEPTOR_CELL_DIFFERENTIATION | GOBP_PHOTORECEPTOR_CELL_DIFFERENTIATION | GOBP_PHOTORECEPTOR_CELL_DIFFERENTIATION | 11/1243 | 62/23056 | 0.1774194 | 3.290894 | 4.311753 | 0.0004304 | 0.0092057 | 0.0080902 | OLFM3/PCARE/PROM1/RP1L1/NTRK2/CDHR1/TH/USH1C/DIO3/CNGB1/DCX | 11 |
| GOBP_REGULATION_OF_MEMBRANE_LIPID_DISTRIBUTION | GOBP_REGULATION_OF_MEMBRANE_LIPID_DISTRIBUTION | GOBP_REGULATION_OF_MEMBRANE_LIPID_DISTRIBUTION | 11/1243 | 62/23056 | 0.1774194 | 3.290894 | 4.311753 | 0.0004304 | 0.0092057 | 0.0080902 | ABCA4/ABCA12/PLSCR5/ATP8A1/ABCB4/XKR5/P2RX7/ATP8A2/SLC4A1/XKR7/ABCG1 | 11 |
| HP_LIMB_DYSTONIA | HP_LIMB_DYSTONIA | HP_LIMB_DYSTONIA | 11/1243 | 62/23056 | 0.1774194 | 3.290894 | 4.311753 | 0.0004304 | 0.0092057 | 0.0080902 | HPCA/SIX3/DLL1/DDC/NODAL/TH/GCH1/MAPT/TUBB4A/ATP1A3/JAM2 | 11 |
| REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | 32/1243 | 314/23056 | 0.1019108 | 1.890311 | 3.791861 | 0.0004311 | 0.0092057 | 0.0080902 | OPRD1/PDE4B/PTGER3/RGS5/RGS16/RGS8/RGS13/ADORA1/GNG4/RGS7/OXER1/CXCR4/PDE1A/GRM2/ADCY5/KNG1/NPY2R/GRM6/GRM4/HTR1E/CNR1/OPRM1/NPY/GRM8/ADRA2A/GAL/CALM1/RGS11/PPY/SSTR2/GNG8/PRKCG | 32 |
| HP_INTELLECTUAL_DISABILITY_SEVERE | HP_INTELLECTUAL_DISABILITY_SEVERE | HP_INTELLECTUAL_DISABILITY_SEVERE | 40/1243 | 424/23056 | 0.0943396 | 1.749875 | 3.720237 | 0.0004428 | 0.0094024 | 0.0082631 | SLC6A17/KCNH1/MYT1L/SOX11/DPYSL5/NRXN1/CTNNA2/KIF5C/SCN1A/UNC80/KIF1A/SATB1/CACNA1D/UROC1/CPLX1/CTNND2/SOX4/GRIK2/DLL1/NTRK2/STXBP1/GRIN1/BRSK2/KCNJ11/TUBA1A/PAH/GABRA5/CHRNA7/ASXL3/TCF4/KCNJ6/CACNG2/TSPAN7/SYP/SHROOM4/ZNF711/PAK3/GRIA3/L1CAM/RAB39B | 40 |
| GOBP_NEUROTRANSMITTER_REUPTAKE | GOBP_NEUROTRANSMITTER_REUPTAKE | GOBP_NEUROTRANSMITTER_REUPTAKE | 8/1243 | 35/23056 | 0.2285714 | 4.239697 | 4.578642 | 0.0004452 | 0.0094024 | 0.0082631 | SLC6A11/SLC6A1/SLC18A1/SLC1A2/DRD2/NOS1/SLC6A2/GPM6B | 8 |
| GOBP_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 7/1243 | 27/23056 | 0.2592593 | 4.808915 | 4.727223 | 0.0004457 | 0.0094024 | 0.0082631 | NPPA/ATP1B1/ANK2/KCNC1/GAL/KCNC2/AKAP6 | 7 |
| GOBP_RESPONSE_TO_AUDITORY_STIMULUS | GOBP_RESPONSE_TO_AUDITORY_STIMULUS | GOBP_RESPONSE_TO_AUDITORY_STIMULUS | 7/1243 | 27/23056 | 0.2592593 | 4.808915 | 4.727223 | 0.0004457 | 0.0094024 | 0.0082631 | NRXN1/CHRNA9/CNTNAP2/KCNC1/NRXN2/DRD2/ATP8A2 | 7 |
| GOMF_INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY | GOMF_INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY | GOMF_INWARD_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY | 7/1243 | 27/23056 | 0.2592593 | 4.808915 | 4.727223 | 0.0004457 | 0.0094024 | 0.0082631 | KCNJ9/KCNH7/KCNJ11/KCNJ8/KCNH6/KCNN1/KCNJ6 | 7 |
| HP_ABSENCE_OF_PUBERTAL_DEVELOPMENT | HP_ABSENCE_OF_PUBERTAL_DEVELOPMENT | HP_ABSENCE_OF_PUBERTAL_DEVELOPMENT | 7/1243 | 27/23056 | 0.2592593 | 4.808915 | 4.727223 | 0.0004457 | 0.0094024 | 0.0082631 | PROK2/ESR1/FGF17/TAC3/MAGEL2/PROKR2/NR0B1 | 7 |
| MEBARKI_HCC_PROGENITOR_WNT_DN | MEBARKI_HCC_PROGENITOR_WNT_DN | MEBARKI_HCC_PROGENITOR_WNT_DN | 14/1243 | 93/23056 | 0.1505376 | 2.792273 | 4.134203 | 0.0004458 | 0.0094024 | 0.0082631 | EPHA10/APOB/PAIP2B/JAKMIP2/SPINK5/TRMT9B/FGD3/RALGPS1/ADARB2/FGD4/ABCD2/TTC6/GCH1/FBXO27 | 14 |
| GOBP_ANION_TRANSMEMBRANE_TRANSPORT | GOBP_ANION_TRANSMEMBRANE_TRANSPORT | GOBP_ANION_TRANSMEMBRANE_TRANSPORT | 27/1243 | 249/23056 | 0.1084337 | 2.011302 | 3.830071 | 0.0004518 | 0.0094755 | 0.0083273 | GABRD/SLC6A1/SLC38A3/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/SLC35D3/CLCN1/SLC24A2/SLC6A5/ANO5/SLC1A2/SLC22A6/GRM5/SLC4A8/SLC17A8/SLC25A29/GABRB3/GABRA5/GABRG3/SLC4A1/SLC1A6/SLC37A1/SLC38A5/SLC7A3 | 27 |
| GOBP_TELENCEPHALON_DEVELOPMENT | GOBP_TELENCEPHALON_DEVELOPMENT | GOBP_TELENCEPHALON_DEVELOPMENT | 27/1243 | 249/23056 | 0.1084337 | 2.011302 | 3.830071 | 0.0004518 | 0.0094755 | 0.0083273 | HTR6/TNR/CNTN2/PROX1/ALK/SLC8A1/SIX3/CXCR4/CDK5R2/SCN5A/TMEM108/PHACTR1/POU3F2/NPY/RELN/CNTNAP2/PAX5/NTRK2/NRG3/SLIT1/TH/SLC1A2/DRD2/ASCL1/RTN4RL1/CDK5R1/SLC32A1 | 27 |
| WP_MAPK_SIGNALING_PATHWAY | WP_MAPK_SIGNALING_PATHWAY | WP_MAPK_SIGNALING_PATHWAY | 27/1243 | 249/23056 | 0.1084337 | 2.011302 | 3.830071 | 0.0004518 | 0.0094755 | 0.0083273 | NGF/NTRK1/PPM1B/CACNA2D2/CACNA1D/FGF12/FGF17/DUSP4/NTRK2/CACNA1B/PTPN5/MAPK8IP1/FGF19/FGF6/FGF14/HSPA2/FGF11/MAPT/CACNG5/CACNG4/CACNG1/MAP4K1/PRKCG/CACNG7/CACNG2/MAPK8IP2/CACNA1F | 27 |
| GOBP_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 15/1243 | 104/23056 | 0.1442308 | 2.675289 | 4.087490 | 0.0004531 | 0.0094755 | 0.0083273 | CLDN19/NTRK1/NRXN1/CLSTN2/SLITRK3/ADGRB3/CNTNAP2/NTRK2/VSTM5/CUX2/SLITRK1/ST8SIA2/CBLN1/SYNDIG1/NLGN3 | 15 |
| HP_OPEN_MOUTH | HP_OPEN_MOUTH | HP_OPEN_MOUTH | 15/1243 | 104/23056 | 0.1442308 | 2.675289 | 4.087490 | 0.0004531 | 0.0094755 | 0.0083273 | KCNH1/SOX11/UNC80/KIF1A/KCNK9/DLK1/RTL1/MAGEL2/ASXL3/TCF4/TUBB4A/KCNJ6/NEXMIF/PAK3/GRIA3 | 15 |
| HP_SELF_INJURIOUS_BEHAVIOR | HP_SELF_INJURIOUS_BEHAVIOR | HP_SELF_INJURIOUS_BEHAVIOR | 22/1243 | 186/23056 | 0.1182796 | 2.193929 | 3.902674 | 0.0004562 | 0.0095220 | 0.0083682 | GABRD/PRKCZ/SLC6A17/NTRK1/MYT1L/KIF5C/UNC80/ABCA12/KIF1A/DLL1/STXBP1/GRIN1/BRSK2/PAH/SLITRK1/MAGEL2/VAMP2/ASXL3/TCF4/CACNG2/NEXMIF/GRIA3 | 22 |
| GOBP_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | GOBP_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | GOBP_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | 28/1243 | 263/23056 | 0.1064639 | 1.974764 | 3.795219 | 0.0004810 | 0.0100233 | 0.0088087 | NPPA/SLC6A17/ADORA1/CHRM3/SLC8A1/SLC6A1/GRIP2/SLC38A3/AGTR1/KNG1/ATP8A1/GUCY1A1/HRH2/DBH/VSTM4/ADRA2A/SLC1A2/PDE2A/KCNJ8/SLC4A8/NOS1/GCH1/C2CD4A/ACE/SLC8A2/EDN3/SLC38A5/SLC7A3 | 28 |
| GOCC_AXON_INITIAL_SEGMENT | GOCC_AXON_INITIAL_SEGMENT | GOCC_AXON_INITIAL_SEGMENT | 6/1243 | 20/23056 | 0.3000000 | 5.564602 | 4.875002 | 0.0004888 | 0.0101339 | 0.0089059 | LRRC7/NFASC/CNTN2/SCN1A/MAP2/KCNQ3 | 6 |
| MAHADEVAN_IMATINIB_RESISTANCE_DN | MAHADEVAN_IMATINIB_RESISTANCE_DN | MAHADEVAN_IMATINIB_RESISTANCE_DN | 6/1243 | 20/23056 | 0.3000000 | 5.564602 | 4.875002 | 0.0004888 | 0.0101339 | 0.0089059 | CXCR4/BCHE/KIT/HAND1/CHODL/ABCG1 | 6 |
| REACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES | REACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES | REACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES | 6/1243 | 20/23056 | 0.3000000 | 5.564602 | 4.875002 | 0.0004888 | 0.0101339 | 0.0089059 | PPFIA4/SLITRK3/PPFIBP2/SLITRK1/SLITRK5/PPFIA3 | 6 |
| GOBP_FOREBRAIN_CELL_MIGRATION | GOBP_FOREBRAIN_CELL_MIGRATION | GOBP_FOREBRAIN_CELL_MIGRATION | 11/1243 | 63/23056 | 0.1746032 | 3.238657 | 4.247374 | 0.0004965 | 0.0102750 | 0.0090299 | HTR6/TNR/CNTN2/CXCR4/CDK5R2/POU3F2/RELN/NRG3/SLIT1/DRD2/CDK5R1 | 11 |
| REACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS | REACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS | REACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS | 14/1243 | 94/23056 | 0.1489362 | 2.762568 | 4.087572 | 0.0004983 | 0.0102946 | 0.0090472 | LRRC7/TUBA3E/TUBB2A/TUBB2B/GRIN1/GRIA4/TUBA1A/TUBA3C/CALM1/MAPT/PPM1E/TUBB4A/RPS6KA6/GRIA3 | 14 |
| CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | 21/1243 | 175/23056 | 0.1200000 | 2.225841 | 3.885760 | 0.0005015 | 0.0103438 | 0.0090904 | UBXN10/RHBG/HHAT/ESRRG/CTNNA2/MYRIP/RBP1/SLC16A10/RUNDC3B/FRMD3/PLPPR1/PHYHIPL/DNAJC12/GFRA1/SLC1A2/SLCO1B1/KCNJ8/HLF/C20orf204/YPEL1/GRK3 | 21 |
| HP_MUSCULAR_HYPOTONIA_OF_THE_TRUNK | HP_MUSCULAR_HYPOTONIA_OF_THE_TRUNK | HP_MUSCULAR_HYPOTONIA_OF_THE_TRUNK | 25/1243 | 226/23056 | 0.1106195 | 2.051844 | 3.793265 | 0.0005376 | 0.0110697 | 0.0097284 | PAX7/SIX3/SCN1A/UNC80/KIF1A/SATB1/CACNA2D2/ADCY5/FGF12/DLL1/DDC/ACTL6B/KCNQ3/STXBP1/GRIN1/DNAJC12/NODAL/TH/KCNJ11/PDE2A/VAMP2/TUBB4A/NEXMIF/DCX/GRIA3 | 25 |
| GOBP_VESICLE_DOCKING_INVOLVED_IN_EXOCYTOSIS | GOBP_VESICLE_DOCKING_INVOLVED_IN_EXOCYTOSIS | GOBP_VESICLE_DOCKING_INVOLVED_IN_EXOCYTOSIS | 8/1243 | 36/23056 | 0.2222222 | 4.121927 | 4.474884 | 0.0005456 | 0.0112061 | 0.0098482 | RAB3C/CPLX2/STXBP1/STX1B/UNC13A/RAB3A/PPFIA3/SNAP25 | 8 |
| GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | 10/1243 | 54/23056 | 0.1851852 | 3.434939 | 4.276246 | 0.0005461 | 0.0112061 | 0.0098482 | RYR2/SCN1A/SCN5A/CACNA1D/FGF12/ANK2/SCN4B/SCN3B/KCNJ8/DSC2 | 10 |
| KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | 12/1243 | 74/23056 | 0.1621622 | 3.007893 | 4.129742 | 0.0005642 | 0.0115596 | 0.0101589 | RYR2/SLC8A1/CTNNA2/CACNA2D2/CACNA1D/CACNG5/CACNG4/CACNG1/DSC2/CACNG7/CACNG2/CACNA1F | 12 |
| GOBP_REGULATION_OF_CARDIAC_CONDUCTION | GOBP_REGULATION_OF_CARDIAC_CONDUCTION | GOBP_REGULATION_OF_CARDIAC_CONDUCTION | 7/1243 | 28/23056 | 0.2500000 | 4.637168 | 4.597002 | 0.0005668 | 0.0115739 | 0.0101714 | RYR2/SLC8A1/ATP2B2/ANK2/SLC8A3/SLC8A2/ATP2B3 | 7 |
| HP_OBSESSIVE_COMPULSIVE_TRAIT | HP_OBSESSIVE_COMPULSIVE_TRAIT | HP_OBSESSIVE_COMPULSIVE_TRAIT | 7/1243 | 28/23056 | 0.2500000 | 4.637168 | 4.597002 | 0.0005668 | 0.0115739 | 0.0101714 | GABRD/SCN1A/ADGRV1/GABRG2/STXBP1/MAGEL2/STX1B | 7 |
| GOBP_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION | 9/1243 | 45/23056 | 0.2000000 | 3.709735 | 4.343358 | 0.0005699 | 0.0115753 | 0.0101727 | ADORA1/IGSF11/NSG1/SCGN/RELN/CALB1/DRD2/CHRNA7/SHISA7 | 9 |
| GOMF_ATPASE_COUPLED_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ATPASE_COUPLED_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ATPASE_COUPLED_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 9/1243 | 45/23056 | 0.2000000 | 3.709735 | 4.343358 | 0.0005699 | 0.0115753 | 0.0101727 | ATP1B1/ATP2B2/ATP13A4/ATP8A1/KCNJ11/KCNJ8/ATP4A/ATP1A3/ATP2B3 | 9 |
| GOMF_NEUROPEPTIDE_RECEPTOR_ACTIVITY | GOMF_NEUROPEPTIDE_RECEPTOR_ACTIVITY | GOMF_NEUROPEPTIDE_RECEPTOR_ACTIVITY | 9/1243 | 45/23056 | 0.2000000 | 3.709735 | 4.343358 | 0.0005699 | 0.0115753 | 0.0101727 | PROKR1/NPY2R/OPRM1/SORCS3/PRLHR/GAL/GPR139/SSTR2/PROKR2 | 9 |
| GOBP_NEURAL_NUCLEUS_DEVELOPMENT | GOBP_NEURAL_NUCLEUS_DEVELOPMENT | GOBP_NEURAL_NUCLEUS_DEVELOPMENT | 11/1243 | 64/23056 | 0.1718750 | 3.188053 | 4.184272 | 0.0005707 | 0.0115753 | 0.0101727 | CHRNB2/CDK5R2/TTBK1/INA/KCNC1/KCNC2/ASCL1/CALM1/CDK5R1/BCL2/MAOB | 11 |
| GOMF_TUBULIN_BINDING | GOMF_TUBULIN_BINDING | GOMF_TUBULIN_BINDING | 36/1243 | 374/23056 | 0.0962567 | 1.785434 | 3.655654 | 0.0005781 | 0.0117048 | 0.0102865 | AGBL4/PDE4B/SGIP1/SYT11/MAP10/KIF3C/DPYSL5/TOGARAM2/EML4/EML6/KIF5C/MAP2/KIF1A/UNC5C/CEP44/JAKMIP2/FYN/PACRG/LZTS1/DPYSL2/STMN4/JAKMIP3/MAP6/KIF21A/KIF5A/EML5/SLC6A2/CDK5R1/MAPT/CAMSAP3/MAST1/BRSK1/NEFH/BEX4/CAPN6/DCX | 36 |
| HP_MYOCLONIC_SEIZURE | HP_MYOCLONIC_SEIZURE | HP_MYOCLONIC_SEIZURE | 23/1243 | 202/23056 | 0.1138614 | 2.111978 | 3.789230 | 0.0005891 | 0.0119091 | 0.0104661 | GABRD/NTNG1/MYT1L/SCN1A/KIF1A/SLC6A1/SATB1/CACNA1D/CPLX1/ADGRV1/GABRG2/DLL1/STXBP1/GRIN1/BRSK2/KCNJ11/CUX2/GABRB3/GABRA5/STX1B/TCF4/CACNG2/NEXMIF | 23 |
| GOBP_NEUROTRANSMITTER_BIOSYNTHETIC_PROCESS | GOBP_NEUROTRANSMITTER_BIOSYNTHETIC_PROCESS | GOBP_NEUROTRANSMITTER_BIOSYNTHETIC_PROCESS | 5/1243 | 14/23056 | 0.3571429 | 6.624526 | 5.025164 | 0.0006006 | 0.0120809 | 0.0106170 | DBH/CHAT/TH/PAH/NOS1 | 5 |
| MIKKELSEN_ES_LCP_WITH_H3K27ME3 | MIKKELSEN_ES_LCP_WITH_H3K27ME3 | MIKKELSEN_ES_LCP_WITH_H3K27ME3 | 5/1243 | 14/23056 | 0.3571429 | 6.624526 | 5.025164 | 0.0006006 | 0.0120809 | 0.0106170 | CHRM1/PDE2A/PPY/KCNN1/CRYBB1 | 5 |
| STEINER_ERYTHROCYTE_MEMBRANE_GENES | STEINER_ERYTHROCYTE_MEMBRANE_GENES | STEINER_ERYTHROCYTE_MEMBRANE_GENES | 5/1243 | 14/23056 | 0.3571429 | 6.624526 | 5.025164 | 0.0006006 | 0.0120809 | 0.0106170 | ADD2/DMTN/ANK1/TMOD1/SLC4A1 | 5 |
| GOMF_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 13/1243 | 85/23056 | 0.1529412 | 2.836856 | 4.050000 | 0.0006035 | 0.0121194 | 0.0106509 | SLC6A11/SLC6A1/SLC38A3/SLC16A10/SLC6A5/SLC1A2/SLC6A15/SLC17A8/SLC25A29/SLC1A6/SLC32A1/SLC38A5/SLC7A3 | 13 |
| MANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN | 25/1243 | 228/23056 | 0.1096491 | 2.033846 | 3.744981 | 0.0006124 | 0.0122768 | 0.0107891 | GPR88/ERC2/ATP13A4/CTNND2/DCDC2/PACSIN1/CA8/PAX5/ALDH1A1/RASEF/WDFY4/NEURL1/SLC4A8/DACH1/KCTD12/STXBP6/DLK1/PLD4/PPM1E/ACE/LOXHD1/ZNF257/ZNF229/SNAP25/PHACTR3 | 25 |
| GOBP_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION | 14/1243 | 96/23056 | 0.1458333 | 2.705015 | 3.996117 | 0.0006191 | 0.0123704 | 0.0108714 | NPPA/PDE4B/ATP1B1/ADORA1/RYR2/SLC8A1/SCN5A/ANK2/NOS1/SLC8A3/CALM1/CHGA/DSC2/HRC | 14 |
| GOMF_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | GOMF_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | GOMF_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | 14/1243 | 96/23056 | 0.1458333 | 2.705015 | 3.996117 | 0.0006191 | 0.0123704 | 0.0108714 | SPINK8/SPINK5/SPINK6/SPINK13/SERPINB9/AMBP/PZP/SERPINA5/SPINT1/WFIKKN2/HMSD/WFDC2/ANOS1/PCSK1N | 14 |
| HP_ABNORMALITY_OF_SALIVATION | HP_ABNORMALITY_OF_SALIVATION | HP_ABNORMALITY_OF_SALIVATION | 21/1243 | 178/23056 | 0.1179775 | 2.188327 | 3.799244 | 0.0006287 | 0.0125411 | 0.0110215 | CHRM3/NRXN1/SCN1A/SATB1/GABRG2/TUBB2B/STXBP1/TH/GCH1/DLK1/RTL1/MAGEL2/UNC13A/ATP1A3/NEFH/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/RAB39B | 21 |
| GOBP_CARDIAC_MUSCLE_CELL_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_CONTRACTION | 12/1243 | 75/23056 | 0.1600000 | 2.967788 | 4.074598 | 0.0006393 | 0.0127322 | 0.0111894 | PDE4B/ADORA1/RYR2/SCN1A/SCN5A/CACNA1D/FGF12/ANK2/SCN4B/SCN3B/KCNJ8/DSC2 | 12 |
| HP_EUNUCHOID_HABITUS | HP_EUNUCHOID_HABITUS | HP_EUNUCHOID_HABITUS | 6/1243 | 21/23056 | 0.2857143 | 5.299621 | 4.705504 | 0.0006533 | 0.0129266 | 0.0113602 | PROK2/FGF17/TAC3/TUBB4A/PROKR2/ANOS1 | 6 |
| HP_HYPOTHALAMIC_GONADOTROPIN_RELEASING_HORMONE_DEFICIENCY | HP_HYPOTHALAMIC_GONADOTROPIN_RELEASING_HORMONE_DEFICIENCY | HP_HYPOTHALAMIC_GONADOTROPIN_RELEASING_HORMONE_DEFICIENCY | 6/1243 | 21/23056 | 0.2857143 | 5.299621 | 4.705504 | 0.0006533 | 0.0129266 | 0.0113602 | IL17RD/PROK2/FGF17/DCC/PROKR2/ANOS1 | 6 |
| HP_STATUS_EPILEPTICUS_WITHOUT_PROMINENT_MOTOR_SYMPTOMS | HP_STATUS_EPILEPTICUS_WITHOUT_PROMINENT_MOTOR_SYMPTOMS | HP_STATUS_EPILEPTICUS_WITHOUT_PROMINENT_MOTOR_SYMPTOMS | 6/1243 | 21/23056 | 0.2857143 | 5.299621 | 4.705504 | 0.0006533 | 0.0129266 | 0.0113602 | GABRD/SCN1A/ADGRV1/GABRG2/STXBP1/STX1B | 6 |
| REACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE | REACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE | REACTOME_TRANSPORT_OF_CONNEXONS_TO_THE_PLASMA_MEMBRANE | 6/1243 | 21/23056 | 0.2857143 | 5.299621 | 4.705504 | 0.0006533 | 0.0129266 | 0.0113602 | TUBA3E/TUBB2A/TUBB2B/TUBA1A/TUBA3C/TUBB4A | 6 |
| OSADA_ASCL1_TARGETS_UP | OSADA_ASCL1_TARGETS_UP | OSADA_ASCL1_TARGETS_UP | 9/1243 | 46/23056 | 0.1956522 | 3.629088 | 4.260751 | 0.0006751 | 0.0133355 | 0.0117196 | RGS16/MYB/DLL1/MTSS1/SCG3/SSTR2/CHGB/PPP1R16B/EDN3 | 9 |
| REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | 15/1243 | 108/23056 | 0.1388889 | 2.576204 | 3.919336 | 0.0006805 | 0.0134219 | 0.0117955 | GNG4/CHRM3/RAPGEF4/CACNA2D2/CACNA1D/ADCY5/GLP1R/STXBP1/ADRA2A/KCNJ11/KCNC2/VAMP2/GNG8/SYT5/SNAP25 | 15 |
| GOBP_ORGANELLE_FUSION | GOBP_ORGANELLE_FUSION | GOBP_ORGANELLE_FUSION | 18/1243 | 143/23056 | 0.1258741 | 2.334798 | 3.822108 | 0.0006983 | 0.0137500 | 0.0120838 | VAV3/SYT11/DYSF/CPLX1/CPLX2/GDAP1/STXBP1/SYT13/SYT7/RAB39A/STXBP6/CPLX3/STX1B/DOC2B/VAMP2/SYT4/RAB3A/SNAP25 | 18 |
| GOBP_ADENYLATE_CYCLASE_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_ADENYLATE_CYCLASE_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_ADENYLATE_CYCLASE_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 19/1243 | 155/23056 | 0.1225806 | 2.273708 | 3.798123 | 0.0006998 | 0.0137565 | 0.0120896 | PDE4B/PTGER3/RAPGEF4/ADCY5/ADGRL3/GLP1R/ADGRB3/MRAP2/CNR1/VIP/OPRM1/ADRA2A/GPR26/CALCB/DRD2/GPR12/CHGA/RIT2/MC4R | 19 |
| GOBP_POSTSYNAPSE_ASSEMBLY | GOBP_POSTSYNAPSE_ASSEMBLY | GOBP_POSTSYNAPSE_ASSEMBLY | 7/1243 | 29/23056 | 0.2413793 | 4.477266 | 4.472791 | 0.0007127 | 0.0139661 | 0.0122737 | NRXN1/GAP43/SLITRK3/NRXN2/CBLN1/NLGN3/NLGN4Y | 7 |
| GOBP_RESPONSE_TO_PAIN | GOBP_RESPONSE_TO_PAIN | GOBP_RESPONSE_TO_PAIN | 7/1243 | 29/23056 | 0.2413793 | 4.477266 | 4.472791 | 0.0007127 | 0.0139661 | 0.0122737 | NTRK1/RELN/DBH/P2RX3/GCH1/SLC6A2/PRKCG | 7 |
| HP_EEG_WITH_SPIKE_WAVE_COMPLEXES | HP_EEG_WITH_SPIKE_WAVE_COMPLEXES | HP_EEG_WITH_SPIKE_WAVE_COMPLEXES | 12/1243 | 76/23056 | 0.1578947 | 2.928738 | 4.020364 | 0.0007225 | 0.0141124 | 0.0124024 | GABRD/SCN1A/SLC6A1/ADGRV1/GABRG2/KCNQ3/STXBP1/CHAT/GABRB3/STX1B/SNAP25/NEXMIF | 12 |
| WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY | WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY | WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY | 12/1243 | 76/23056 | 0.1578947 | 2.928738 | 4.020364 | 0.0007225 | 0.0141124 | 0.0124024 | RYR2/SLC8A1/CTNNA2/CACNA2D2/CACNA1D/CACNG5/CACNG4/CACNG1/DSC2/CACNG7/CACNG2/CACNA1F | 12 |
| BROWNE_HCMV_INFECTION_48HR_UP | BROWNE_HCMV_INFECTION_48HR_UP | BROWNE_HCMV_INFECTION_48HR_UP | 21/1243 | 180/23056 | 0.1166667 | 2.164012 | 3.742519 | 0.0007282 | 0.0142003 | 0.0124796 | AJAP1/PIK3R3/PTGER3/DPT/RGS16/GREB1/CTNNA2/CXCR4/IGFBP2/SAP30/FUT9/CD24/RUNDC3B/MTSS1/TMOD1/CHST1/KLRG1/HSPA2/ONECUT1/EDN3/ABCG1 | 21 |
| GOBP_SODIUM_ION_HOMEOSTASIS | GOBP_SODIUM_ION_HOMEOSTASIS | GOBP_SODIUM_ION_HOMEOSTASIS | 10/1243 | 56/23056 | 0.1785714 | 3.312263 | 4.135497 | 0.0007369 | 0.0143309 | 0.0125943 | ATP1B1/ADORA1/SLC8A1/SCN7A/AGTR1/TFAP2B/DRD2/ACE/ATP4A/ATP1A3 | 10 |
| MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | 27/1243 | 257/23056 | 0.1050584 | 1.948693 | 3.650858 | 0.0007372 | 0.0143309 | 0.0125943 | SUSD4/GREB1/MAP2/FGFBP2/TUBB2B/ELOVL2/SOX4/PKIB/MYB/ESR1/OLFM1/ADRA2A/AFAP1L2/ATRNL1/GFRA1/MPPED2/RERG/HOXC10/CCNA1/SERPINA5/CRABP1/ABAT/MAPT/BCL2/PLIN5/TIAM1/ARHGAP36 | 27 |
| GOBP_ENDOCRINE_SYSTEM_DEVELOPMENT | GOBP_ENDOCRINE_SYSTEM_DEVELOPMENT | GOBP_ENDOCRINE_SYSTEM_DEVELOPMENT | 17/1243 | 132/23056 | 0.1287879 | 2.388844 | 3.819933 | 0.0007480 | 0.0145170 | 0.0127579 | RAP1GAP/SIX3/HOXD3/GATA2/SOX2/PDGFRA/ISL1/SOX4/POU3F2/RFX6/DLL1/CDKN1C/DRD2/ASCL1/ONECUT1/ONECUT2/NR0B1 | 17 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | 19/1243 | 156/23056 | 0.1217949 | 2.259133 | 3.766836 | 0.0007574 | 0.0146762 | 0.0128978 | TAL1/DNAJC6/OLFM3/RSAD2/MEIS1/OSBPL6/TUBB2A/SOX4/MAP7/DEFB1/CALB1/ENPP2/MTSS1/ALDH1A1/GCH1/PLD4/KLF1/LAMP5/RBM11 | 19 |
| GOBP_REGULATION_OF_DENDRITE_DEVELOPMENT | GOBP_REGULATION_OF_DENDRITE_DEVELOPMENT | GOBP_REGULATION_OF_DENDRITE_DEVELOPMENT | 14/1243 | 98/23056 | 0.1428571 | 2.649810 | 3.906973 | 0.0007639 | 0.0147776 | 0.0129869 | ELAVL4/CHRNB2/ALK/BCL11A/PACSIN1/ADGRB3/RELN/LZTS1/CUX2/CHRNA3/DCC/BMP7/ZDHHC15/PAK3 | 14 |
| DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 27/1243 | 258/23056 | 0.1046512 | 1.941140 | 3.628910 | 0.0007822 | 0.0151076 | 0.0132769 | VAV3/NFASC/ALK/CXCR4/SCN3A/SATB1/GATA2/BCHE/ANK2/JAKMIP2/ANK1/EYA1/PAX5/EPB41L4B/NEBL/VSTM4/NELL1/SCN3B/PCDH17/IRS2/CLMN/MAGEL2/ABAT/GRK3/GPM6B/DCX/SEPTIN6 | 27 |
| GOBP_EAR_DEVELOPMENT | GOBP_EAR_DEVELOPMENT | GOBP_EAR_DEVELOPMENT | 24/1243 | 219/23056 | 0.1095890 | 2.032731 | 3.665644 | 0.0007851 | 0.0151396 | 0.0133050 | HPCA/PLPPR4/PROX1/KCNK3/FRZB/GATA2/SOX2/CHRNA9/ADGRV1/LHFPL5/DLL1/TWIST1/EYA1/CALB1/ROR2/CDH23/USH1C/SLC17A8/ATP8A2/GSC/GABRA5/STRC/BCL2/MAFB | 24 |
| CERVERA_SDHB_TARGETS_1_UP | CERVERA_SDHB_TARGETS_1_UP | CERVERA_SDHB_TARGETS_1_UP | 16/1243 | 121/23056 | 0.1322314 | 2.452717 | 3.824589 | 0.0007921 | 0.0152444 | 0.0133971 | RBP7/PTGER3/SUSD4/KIF3C/IGFBP2/SPOCK3/PLEKHG4B/PACSIN1/DUSP4/PLXDC2/SCN4B/TUBA1A/ASCL1/C2CD4A/MFAP4/JAM2 | 16 |
| GOBP_NEGATIVE_REGULATION_OF_BLOOD_PRESSURE | GOBP_NEGATIVE_REGULATION_OF_BLOOD_PRESSURE | GOBP_NEGATIVE_REGULATION_OF_BLOOD_PRESSURE | 9/1243 | 47/23056 | 0.1914894 | 3.551874 | 4.180417 | 0.0007955 | 0.0152444 | 0.0133971 | NPPA/ADORA1/CNR1/NPY/DRD2/NOS1/KL/GCH1/ABAT | 9 |
| GOBP_PHENOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | GOBP_PHENOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | GOBP_PHENOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS | 9/1243 | 47/23056 | 0.1914894 | 3.551874 | 4.180417 | 0.0007955 | 0.0152444 | 0.0133971 | HAND2/DDC/DBH/TH/PMEL/TPH2/PAH/KL/GCH1 | 9 |
| HP_BILATERAL_TONIC_CLONIC_SEIZURE_WITH_GENERALIZED_ONSET | HP_BILATERAL_TONIC_CLONIC_SEIZURE_WITH_GENERALIZED_ONSET | HP_BILATERAL_TONIC_CLONIC_SEIZURE_WITH_GENERALIZED_ONSET | 9/1243 | 47/23056 | 0.1914894 | 3.551874 | 4.180417 | 0.0007955 | 0.0152444 | 0.0133971 | GABRD/SCN1A/SLC6A1/CPLX1/GABRG2/KCNQ3/STXBP1/GABRA5/NEXMIF | 9 |
| GOBP_FEAR_RESPONSE | GOBP_FEAR_RESPONSE | GOBP_FEAR_RESPONSE | 8/1243 | 38/23056 | 0.2105263 | 3.904984 | 4.278210 | 0.0008012 | 0.0153289 | 0.0134714 | ASIC4/GRIK2/BRINP1/DBH/ADRA2A/GABRA5/BCL2/MAPK8IP2 | 8 |
| HP_GENERALIZED_MYOCLONIC_SEIZURE | HP_GENERALIZED_MYOCLONIC_SEIZURE | HP_GENERALIZED_MYOCLONIC_SEIZURE | 20/1243 | 169/23056 | 0.1183432 | 2.195109 | 3.722348 | 0.0008048 | 0.0153736 | 0.0135107 | GABRD/NTNG1/MYT1L/SCN1A/KIF1A/SLC6A1/CPLX1/ADGRV1/GABRG2/DLL1/STXBP1/GRIN1/BRSK2/KCNJ11/CUX2/GABRB3/STX1B/TCF4/CACNG2/NEXMIF | 20 |
| WP_CIRCADIAN_RHYTHM_GENES | WP_CIRCADIAN_RHYTHM_GENES | WP_CIRCADIAN_RHYTHM_GENES | 23/1243 | 207/23056 | 0.1111111 | 2.060964 | 3.660265 | 0.0008273 | 0.0157784 | 0.0138665 | HCRTR1/CHRNB2/NTRK1/ADORA1/PROX1/SIX3/KCNH7/PROK2/PRKG2/NPY2R/DDC/SFTPC/OPN4/TH/CHRM1/DRD2/TPH2/F7/MAGEL2/ARNT2/HS3ST2/PRKCG/PROKR2 | 23 |
| GOBP_CELL_MATURATION | GOBP_CELL_MATURATION | GOBP_CELL_MATURATION | 21/1243 | 182/23056 | 0.1153846 | 2.140231 | 3.686533 | 0.0008411 | 0.0160159 | 0.0140751 | EPHA8/TAL1/CNTN2/RHEX/SIX3/BCL11A/FEV/ROPN1/ROPN1B/GATA2/BFSP2/ADGRB3/ACTL6B/CNTNAP2/DEFB1/CDKN1C/ASCL1/SRRM4/C1QL1/BCL2/PLA2G3 | 21 |
| GOBP_FATTY_ACID_TRANSPORT | GOBP_FATTY_ACID_TRANSPORT | GOBP_FATTY_ACID_TRANSPORT | 14/1243 | 99/23056 | 0.1414141 | 2.623045 | 3.863233 | 0.0008464 | 0.0160919 | 0.0141419 | RBP7/RBP1/ACSL1/FABP6/SYK/DRD2/ABCD2/PLA2G1B/P2RX7/IRS2/SLC27A2/CRABP1/ACE/PLA2G3 | 14 |
| GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER | GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER | GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER | 11/1243 | 67/23056 | 0.1641791 | 3.045304 | 4.002172 | 0.0008511 | 0.0161561 | 0.0141984 | HTR6/OPRD1/CHRM3/HRH2/HTR1E/CNR1/OPRM1/NPY/CHRM1/SSTR2/HRH3 | 11 |
| GOBP_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 6/1243 | 22/23056 | 0.2727273 | 5.058729 | 4.546499 | 0.0008576 | 0.0162444 | 0.0142760 | SLC8A1/SCN5A/CACNA1D/ANK2/SCN4B/SCN3B | 6 |
| GOMF_INHIBITORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_INHIBITORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_INHIBITORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | 5/1243 | 15/23056 | 0.3333333 | 6.182891 | 4.793221 | 0.0008611 | 0.0162444 | 0.0142760 | GABRG1/GLRA3/GABRG2/GABRA5/GABRG3 | 5 |
| HP_DYSGENESIS_OF_THE_HIPPOCAMPUS | HP_DYSGENESIS_OF_THE_HIPPOCAMPUS | HP_DYSGENESIS_OF_THE_HIPPOCAMPUS | 5/1243 | 15/23056 | 0.3333333 | 6.182891 | 4.793221 | 0.0008611 | 0.0162444 | 0.0142760 | DPYSL5/SCN1A/GABRG2/STXBP1/DCC | 5 |
| HP_GENERALIZED_DYSTONIA | HP_GENERALIZED_DYSTONIA | HP_GENERALIZED_DYSTONIA | 5/1243 | 15/23056 | 0.3333333 | 6.182891 | 4.793221 | 0.0008611 | 0.0162444 | 0.0142760 | HPCA/TH/GCH1/TUBB4A/JAM2 | 5 |
| GOBP_POSITIVE_REGULATION_OF_HORMONE_SECRETION | GOBP_POSITIVE_REGULATION_OF_HORMONE_SECRETION | GOBP_POSITIVE_REGULATION_OF_HORMONE_SECRETION | 16/1243 | 122/23056 | 0.1311475 | 2.432613 | 3.787296 | 0.0008670 | 0.0163300 | 0.0143512 | SOX11/VSNL1/MYRIP/GPR27/ISL1/SOX4/GPLD1/RFX6/TFR2/GAL/DRD2/IRS2/ABAT/DOC2B/EDN3/PLA2G3 | 16 |
| HP_GENERALIZED_ONSET_MOTOR_SEIZURE | HP_GENERALIZED_ONSET_MOTOR_SEIZURE | HP_GENERALIZED_ONSET_MOTOR_SEIZURE | 23/1243 | 208/23056 | 0.1105769 | 2.051055 | 3.634909 | 0.0008838 | 0.0166007 | 0.0145891 | GABRD/NTNG1/MYT1L/SCN1A/KIF1A/SLC6A1/SATB1/CPLX1/ADGRV1/GABRG2/DLL1/KCNQ3/STXBP1/GRIN1/BRSK2/KCNJ11/CUX2/GABRB3/GABRA5/STX1B/TCF4/CACNG2/NEXMIF | 23 |
| GOBP_RESPONSE_TO_XENOBIOTIC_STIMULUS | GOBP_RESPONSE_TO_XENOBIOTIC_STIMULUS | GOBP_RESPONSE_TO_XENOBIOTIC_STIMULUS | 38/1243 | 411/23056 | 0.0924574 | 1.714962 | 3.491230 | 0.0008863 | 0.0166007 | 0.0145891 | CYP2J2/PDE4B/VAV3/NTRK1/KCNK3/SLC8A1/SULT1C4/CXCR4/IGFBP2/SLC6A11/GRM2/BCHE/SFRP2/ACSL1/GPLD1/TFAP2B/ADCYAP1R1/DDC/FBP1/GRIN1/TH/KCNJ11/KCNC1/SLC1A2/GAL/SHANK2/DRD2/ENO2/NOS1/P2RX7/GABRG3/ABAT/SLC6A2/PPM1E/ACE/BCL2/AMH/MAOB | 38 |
| GOCC_DENDRITE_CYTOPLASM | GOCC_DENDRITE_CYTOPLASM | GOCC_DENDRITE_CYTOPLASM | 7/1243 | 30/23056 | 0.2333333 | 4.328024 | 4.354098 | 0.0008868 | 0.0166007 | 0.0145891 | HPCA/GRIK3/KIF5C/MAP2/GRIK2/OPRM1/KIF5A | 7 |
| GOMF_ORGANIC_ACID_SODIUM_SYMPORTER_ACTIVITY | GOMF_ORGANIC_ACID_SODIUM_SYMPORTER_ACTIVITY | GOMF_ORGANIC_ACID_SODIUM_SYMPORTER_ACTIVITY | 7/1243 | 30/23056 | 0.2333333 | 4.328024 | 4.354098 | 0.0008868 | 0.0166007 | 0.0145891 | SLC6A11/SLC6A1/SLC10A4/SLC6A5/SLC1A2/SLC6A15/SLC1A6 | 7 |
| FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP | FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP | FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP | 36/1243 | 383/23056 | 0.0939948 | 1.743478 | 3.502464 | 0.0008905 | 0.0166443 | 0.0146274 | KANK4/VAV3/RGS5/IRF6/HHAT/RSAD2/C2orf50/GREB1/TOGARAM2/EML6/CXXC4/TMEM154/NPY2R/C7/MRAP2/ZNF716/NEBL/VSTM4/DNAJC12/SLC22A24/ASCL1/FOXN4/CUX2/HRK/GPC5/TTC6/HSPA2/SERPINA5/CLMN/CRABP1/TEX14/APCDD1/ZNF492/CTCFL/SHROOM4/CHRDL1 | 36 |
| GOBP_REGULATION_OF_BLOOD_PRESSURE | GOBP_REGULATION_OF_BLOOD_PRESSURE | GOBP_REGULATION_OF_BLOOD_PRESSURE | 21/1243 | 183/23056 | 0.1147541 | 2.128536 | 3.658810 | 0.0009029 | 0.0168509 | 0.0148090 | NPPA/ADORA1/GRIP2/AGTR1/CPA3/GUCY1A1/GLP1R/CNR1/DLL1/NPY/DRD2/PTPRO/TAC3/NOS1/KL/GCH1/CHGA/ABAT/ACE/KLK2/EDN3 | 21 |
| GOBP_LEUKOCYTE_DEGRANULATION | GOBP_LEUKOCYTE_DEGRANULATION | GOBP_LEUKOCYTE_DEGRANULATION | 12/1243 | 78/23056 | 0.1538462 | 2.853642 | 3.914511 | 0.0009163 | 0.0170746 | 0.0150056 | GATA2/KIT/CPLX2/SYK/STXBP1/SPI1/CHGA/VAMP2/NKG7/ITGB2/PLA2G3/IL13RA2 | 12 |
| WP_NOCGMPPKG_MEDIATED_NEUROPROTECTION | WP_NOCGMPPKG_MEDIATED_NEUROPROTECTION | WP_NOCGMPPKG_MEDIATED_NEUROPROTECTION | 9/1243 | 48/23056 | 0.1875000 | 3.477876 | 4.102241 | 0.0009329 | 0.0173570 | 0.0152537 | NPPA/PRKG2/GUCY1A1/GRIN1/PDE2A/NOS1/CALM1/CNGB1/BCL2 | 9 |
| GOBP_NEURON_PROJECTION_ORGANIZATION | GOBP_NEURON_PROJECTION_ORGANIZATION | GOBP_NEURON_PROJECTION_ORGANIZATION | 13/1243 | 89/23056 | 0.1460674 | 2.709357 | 3.856879 | 0.0009416 | 0.0174640 | 0.0153478 | KIF1A/CTNND2/FYN/RELN/ABCD2/CUX2/CHRNA7/CDK5R1/SRCIN1/ATP1A3/SHANK1/ZDHHC15/PAK3 | 13 |
| GOBP_REGULATION_OF_ANION_TRANSPORT | GOBP_REGULATION_OF_ANION_TRANSPORT | GOBP_REGULATION_OF_ANION_TRANSPORT | 13/1243 | 89/23056 | 0.1460674 | 2.709357 | 3.856879 | 0.0009416 | 0.0174640 | 0.0153478 | ADORA1/SLC6A1/SLC38A3/GRM2/PRKG2/SYK/STXBP1/GRM5/P2RX7/ABAT/SYT4/HRH3/PLA2G3 | 13 |
| GOBP_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_REGULATION_OF_DEVELOPMENTAL_GROWTH | 32/1243 | 329/23056 | 0.0972644 | 1.804126 | 3.506804 | 0.0009553 | 0.0176615 | 0.0155213 | NGF/TNR/PROX1/BCL11A/CXCR4/MAP2/SEMA5B/POU4F2/FSTL4/RIMS1/POU3F2/DLL1/DPYSL2/OLFM1/SLIT1/RAG2/DRD2/RASAL1/ATP8A2/AKAP6/DIO3/ISLR2/CDK5R1/MAPT/SYT4/DCC/BCL2/UNC13A/SYT3/CACNG7/SASH3/L1CAM | 32 |
| HP_INTELLECTUAL_DISABILITY_PROFOUND | HP_INTELLECTUAL_DISABILITY_PROFOUND | HP_INTELLECTUAL_DISABILITY_PROFOUND | 19/1243 | 159/23056 | 0.1194969 | 2.216508 | 3.674385 | 0.0009555 | 0.0176615 | 0.0155213 | MYT1L/SCN1A/UNC80/KIF1A/DLL1/STXBP1/GRIN1/BRSK2/SLC1A2/ASXL3/TCF4/KCNJ6/CACNG2/TSPAN7/SYP/SHROOM4/ZNF711/PAK3/RAB39B | 19 |
| GOBP_EATING_BEHAVIOR | GOBP_EATING_BEHAVIOR | GOBP_EATING_BEHAVIOR | 8/1243 | 39/23056 | 0.2051282 | 3.804856 | 4.184841 | 0.0009609 | 0.0176615 | 0.0155213 | OPRD1/CNTN2/OPRM1/NPY/TH/ATP8A2/ACE/MC4R | 8 |
| GOBP_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | GOBP_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | GOBP_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | 8/1243 | 39/23056 | 0.2051282 | 3.804856 | 4.184841 | 0.0009609 | 0.0176615 | 0.0155213 | SCN5A/CACNA1D/ANK2/ISL1/SCN4B/SCN3B/KCNH6/DSC2 | 8 |
| GOCC_CELL_CORTEX_REGION | GOCC_CELL_CORTEX_REGION | GOCC_CELL_CORTEX_REGION | 8/1243 | 39/23056 | 0.2051282 | 3.804856 | 4.184841 | 0.0009609 | 0.0176615 | 0.0155213 | PRKCZ/RIMS3/BSN/ERC2/RIMS1/INSC/UNC13A/PPFIA3 | 8 |
| HP_HYPERVENTILATION | HP_HYPERVENTILATION | HP_HYPERVENTILATION | 8/1243 | 39/23056 | 0.2051282 | 3.804856 | 4.184841 | 0.0009609 | 0.0176615 | 0.0155213 | CHRNB2/NRXN1/GABRG2/CNTNAP2/CHRNA2/FBP1/GABRB3/TCF4 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION | 11/1243 | 68/23056 | 0.1617647 | 3.000521 | 3.943731 | 0.0009667 | 0.0177284 | 0.0155802 | RSAD2/VSNL1/KLF7/CD200/OPRM1/ADRA2A/KCNJ11/DRD2/CHGA/SRCIN1/SYT4 | 11 |
| HP_INCOMPLETE_PENETRANCE | HP_INCOMPLETE_PENETRANCE | HP_INCOMPLETE_PENETRANCE | 18/1243 | 147/23056 | 0.1224490 | 2.271266 | 3.691072 | 0.0009675 | 0.0177284 | 0.0155802 | KCNK3/SIX3/PROK2/GABRG2/RELN/CHRNA2/EYA1/CDH23/KIF5A/SMAD9/GABRB3/CHRNA7/GUCY2D/DCC/ATP1A3/PRKCG/PROKR2/DCX | 18 |
| HP_FEMALE_SEXUAL_DYSFUNCTION | HP_FEMALE_SEXUAL_DYSFUNCTION | HP_FEMALE_SEXUAL_DYSFUNCTION | 10/1243 | 58/23056 | 0.1724138 | 3.198047 | 4.000980 | 0.0009796 | 0.0179231 | 0.0157513 | DNAJC6/IL17RD/PROK2/FGF17/CDH23/TAC3/DCC/RTN2/PROKR2/ANOS1 | 10 |
| GOMF_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 31/1243 | 317/23056 | 0.0977918 | 1.813908 | 3.483211 | 0.0010419 | 0.0190348 | 0.0167282 | GABRD/SLC6A11/SLC6A1/SLC38A3/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/SLC35D3/CLCN1/SLC18A1/SLC24A2/SLC6A5/ANO5/SLC1A2/SLC22A6/SLCO1B1/SLC4A8/SLC17A8/SLC25A29/GABRB3/GABRA5/GABRG3/SLC6A2/SLC4A1/SLC1A6/SLC32A1/SLC37A1/SLC38A5/SLC7A3 | 31 |
| RODWELL_AGING_KIDNEY_NO_BLOOD_DN | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | 18/1243 | 148/23056 | 0.1216216 | 2.255920 | 3.658976 | 0.0010472 | 0.0191023 | 0.0167875 | PTGER3/ESRRG/KNG1/ARFGEF3/THSD7A/TPD52/FRMD3/PLPPR1/RALGPS1/NEBL/MPPED2/SHANK2/BTBD11/CRABP1/BMP7/TSPAN7/ZNF711/GPRASP1 | 18 |
| HP_DISINHIBITION | HP_DISINHIBITION | HP_DISINHIBITION | 22/1243 | 198/23056 | 0.1111111 | 2.060964 | 3.579105 | 0.0010615 | 0.0193350 | 0.0169920 | DNAJC6/NTRK1/DPYSL5/SIX3/SCN3A/SCN1A/FGF12/GABRG2/GRIK2/DLL1/ACTL6B/RELN/NTRK2/STXBP1/CACNA1B/CELF2/NODAL/SLC1A2/MAGEL2/GABRA5/MAPT/ATP1A3 | 22 |
| HP_GENERALIZED_ONSET_SEIZURE | HP_GENERALIZED_ONSET_SEIZURE | HP_GENERALIZED_ONSET_SEIZURE | 34/1243 | 359/23056 | 0.0947075 | 1.756699 | 3.449423 | 0.0010715 | 0.0194877 | 0.0171263 | GABRD/NTNG1/CNTN2/MYT1L/SCN1A/KIF1A/SLC6A1/SATB1/CPLX1/CTNND2/ADGRV1/GABRG2/GRIK2/DLL1/RELN/CNTNAP2/KCNQ3/STXBP1/GRIN1/BRSK2/KCNJ11/CUX2/GABRB3/GABRA5/STX1B/TCF4/CACNG2/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/DCX/RAB39B | 34 |
| GOBP_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | 20/1243 | 173/23056 | 0.1156069 | 2.144355 | 3.606516 | 0.0010787 | 0.0195597 | 0.0171896 | DLGAP3/ADORA1/MTRNR2L13/OPRM1/RELN/DLGAP2/NEURL1/ADRA2A/CNIH2/BEGAIN/GSG1L/WFIKKN2/CACNG5/CACNG4/SHANK1/CACNG7/SHISA7/CACNG2/MAPK8IP2/NLGN3 | 20 |
| MOHANKUMAR_HOXA1_TARGETS_DN | MOHANKUMAR_HOXA1_TARGETS_DN | MOHANKUMAR_HOXA1_TARGETS_DN | 20/1243 | 173/23056 | 0.1156069 | 2.144355 | 3.606516 | 0.0010787 | 0.0195597 | 0.0171896 | SLC22A15/SLC8A1/KIF5C/SLITRK3/FGF12/RNF150/GUCY1A1/SPINK5/JAZF1/DIRAS2/DRD2/RASAL1/FGF11/DSC2/SHANK1/SYNDIG1/MAFB/BMP7/PLA2G3/BEX1 | 20 |
| MCCLUNG_DELTA_FOSB_TARGETS_2WK | MCCLUNG_DELTA_FOSB_TARGETS_2WK | MCCLUNG_DELTA_FOSB_TARGETS_2WK | 9/1243 | 49/23056 | 0.1836735 | 3.406899 | 4.026117 | 0.0010890 | 0.0196871 | 0.0173015 | VSNL1/SCN1A/CADPS/TUBB2A/ELAVL2/OLFM1/INA/NEFH/INPP5J | 9 |
| REACTOME_RECYCLING_PATHWAY_OF_L1 | REACTOME_RECYCLING_PATHWAY_OF_L1 | REACTOME_RECYCLING_PATHWAY_OF_L1 | 9/1243 | 49/23056 | 0.1836735 | 3.406899 | 4.026117 | 0.0010890 | 0.0196871 | 0.0173015 | TUBA3E/TUBB2A/TUBB2B/DPYSL2/TUBA1A/TUBA3C/TUBB4A/RPS6KA6/L1CAM | 9 |
| HP_RETINAL_THINNING | HP_RETINAL_THINNING | HP_RETINAL_THINNING | 7/1243 | 31/23056 | 0.2258065 | 4.188410 | 4.240486 | 0.0010927 | 0.0196968 | 0.0173100 | ABCA4/PDE6B/PROM1/GRM6/GRK1/LAMA1/CACNA1F | 7 |
| REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | 7/1243 | 31/23056 | 0.2258065 | 4.188410 | 4.240486 | 0.0010927 | 0.0196968 | 0.0173100 | GRIP2/GRIA4/CACNG4/PRKCG/CACNG2/TSPAN7/GRIA3 | 7 |
| GOMF_CLATHRIN_BINDING | GOMF_CLATHRIN_BINDING | GOMF_CLATHRIN_BINDING | 11/1243 | 69/23056 | 0.1594203 | 2.957035 | 3.886354 | 0.0010950 | 0.0197078 | 0.0173197 | DNAJC6/SYT11/NSG1/NSG2/SNAP91/SYT8/SYT13/SYT7/SYT4/SYT3/SYT5 | 11 |
| GOCC_CELL_LEADING_EDGE | GOCC_CELL_LEADING_EDGE | GOCC_CELL_LEADING_EDGE | 38/1243 | 416/23056 | 0.0913462 | 1.694350 | 3.411515 | 0.0011068 | 0.0197632 | 0.0173684 | PRKCZ/OPRD1/HPCA/THEM4/ADORA1/CXCR4/ATP2B2/GABRG1/UNC5C/ADGRV1/PSD2/GABRG2/UNC5A/PACSIN1/OPRM1/CNTNAP2/MTSS1/FGD3/SH2D3C/PSD/KCNC1/SLC1A2/PTPRO/FGD4/KCNC2/GABRA5/GABRG3/DUOX1/CARMIL2/PARD6A/SRCIN1/MAPT/KCNC3/SHISA7/LAMP5/SAMSN1/S100B/INPP5J | 38 |
| GOBP_PHASIC_SMOOTH_MUSCLE_CONTRACTION | GOBP_PHASIC_SMOOTH_MUSCLE_CONTRACTION | GOBP_PHASIC_SMOOTH_MUSCLE_CONTRACTION | 6/1243 | 23/23056 | 0.2608696 | 4.838784 | 4.396861 | 0.0011078 | 0.0197632 | 0.0173684 | PTGER3/KIT/P2RX3/DRD2/SSTR2/EDN3 | 6 |
| GOBP_POSITIVE_REGULATION_OF_AMINO_ACID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_AMINO_ACID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_AMINO_ACID_TRANSPORT | 6/1243 | 23/23056 | 0.2608696 | 4.838784 | 4.396861 | 0.0011078 | 0.0197632 | 0.0173684 | SLC6A1/SLC38A3/STXBP1/P2RX7/ABAT/SYT4 | 6 |
| GOBP_REGULATION_OF_LONG_TERM_NEURONAL_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_LONG_TERM_NEURONAL_SYNAPTIC_PLASTICITY | GOBP_REGULATION_OF_LONG_TERM_NEURONAL_SYNAPTIC_PLASTICITY | 6/1243 | 23/23056 | 0.2608696 | 4.838784 | 4.396861 | 0.0011078 | 0.0197632 | 0.0173684 | KIT/GRIK2/NEURL1/GRM5/DRD2/SYP | 6 |
| GOCC_PHOTORECEPTOR_DISC_MEMBRANE | GOCC_PHOTORECEPTOR_DISC_MEMBRANE | GOCC_PHOTORECEPTOR_DISC_MEMBRANE | 6/1243 | 23/23056 | 0.2608696 | 4.838784 | 4.396861 | 0.0011078 | 0.0197632 | 0.0173684 | ABCA4/PDE6B/GUCA1A/OPN4/GRK1/GUCY2D | 6 |
| REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | 6/1243 | 23/23056 | 0.2608696 | 4.838784 | 4.396861 | 0.0011078 | 0.0197632 | 0.0173684 | TUBA3E/TUBB2A/TUBB2B/TUBA1A/TUBA3C/TUBB4A | 6 |
| HP_TYPICAL_ABSENCE_SEIZURE | HP_TYPICAL_ABSENCE_SEIZURE | HP_TYPICAL_ABSENCE_SEIZURE | 10/1243 | 59/23056 | 0.1694915 | 3.143843 | 3.935897 | 0.0011234 | 0.0200075 | 0.0175831 | MYT1L/KIF1A/GABRG2/DLL1/STXBP1/GRIN1/BRSK2/GABRB3/TCF4/CACNG2 | 10 |
| HP_DYSKINESIA | HP_DYSKINESIA | HP_DYSKINESIA | 26/1243 | 251/23056 | 0.1035857 | 1.921376 | 3.503639 | 0.0011248 | 0.0200075 | 0.0175831 | DNAJC6/MYT1L/SCN3A/UNC80/KIF1A/ADCY5/FGF12/GABRG2/GRIK2/DLL1/ACTL6B/NTRK2/STXBP1/GRIN1/CACNA1B/CELF2/BRSK2/SLC1A2/CUX2/FGF14/GABRB3/GABRA5/TCF4/JAM2/CACNG2/RAB39B | 26 |
| GOBP_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION | GOBP_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION | GOBP_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION | 8/1243 | 40/23056 | 0.2000000 | 3.709735 | 4.094513 | 0.0011451 | 0.0203097 | 0.0178487 | NPPA/ATP1B1/SCN5A/CACNA1D/ANK2/SCN4B/KCNJ8/KCNH6 | 8 |
| HALLMARK_PANCREAS_BETA_CELLS | HALLMARK_PANCREAS_BETA_CELLS | HALLMARK_PANCREAS_BETA_CELLS | 8/1243 | 40/23056 | 0.2000000 | 3.709735 | 4.094513 | 0.0011451 | 0.0203097 | 0.0178487 | ISL1/SCGN/STXBP1/SYT13/CHGA/MAFB/PAK3/DCX | 8 |
| GOBP_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT | GOBP_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT | GOBP_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT | 12/1243 | 80/23056 | 0.1500000 | 2.782301 | 3.811968 | 0.0011516 | 0.0203951 | 0.0179238 | AGBL4/CHRNB2/CNTN2/MAP2/GATA2/NPY/NTRK2/DRD2/ASCL1/MAPT/DCC/NOVA2 | 12 |
| GOBP_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 13/1243 | 91/23056 | 0.1428571 | 2.649810 | 3.764280 | 0.0011626 | 0.0205600 | 0.0180686 | NGF/BRINP2/PROX1/SOX11/HOXD3/GATA2/MMD2/BRINP1/ASCL1/DUOXA1/RNF112/TCF4/BMP7 | 13 |
| FOSTER_KDM1A_TARGETS_UP | FOSTER_KDM1A_TARGETS_UP | FOSTER_KDM1A_TARGETS_UP | 27/1243 | 265/23056 | 0.1018868 | 1.889865 | 3.477969 | 0.0011691 | 0.0206445 | 0.0181429 | CYP2J2/TSPAN2/THEM5/SLC30A3/DNAJC5G/HOXD8/MAP2/CD200/UROC1/BFSP2/PPP2R2C/ADH4/ANK2/SELENOP/RIMS1/RELN/CNTNAP2/DUSP26/NTRK2/DIRAS2/OTOG/MANSC1/PMEL/TPH2/CRABP1/SYT5/XPNPEP2 | 27 |
| GOCC_PLASMA_MEMBRANE_SIGNALING_RECEPTOR_COMPLEX | GOCC_PLASMA_MEMBRANE_SIGNALING_RECEPTOR_COMPLEX | GOCC_PLASMA_MEMBRANE_SIGNALING_RECEPTOR_COMPLEX | 30/1243 | 306/23056 | 0.0980392 | 1.818497 | 3.440707 | 0.0011955 | 0.0207486 | 0.0182344 | GRIK3/OLFM3/CHRNB2/CD8A/CD8B/CHRNA1/CHRNA9/BMPR1B/TLR2/GRIK2/TFR2/CHRNA2/SYK/GRIN1/CNIH2/GRIA4/HTR3A/CD3G/GRIK4/CHRFAM7A/CHRNA7/CHRNA3/CHRNB4/CACNG5/CACNG4/CACNG7/SHISA7/ITGB2/CACNG2/GRIA3 | 30 |
| GOBP_SPHINGOLIPID_METABOLIC_PROCESS | GOBP_SPHINGOLIPID_METABOLIC_PROCESS | GOBP_SPHINGOLIPID_METABOLIC_PROCESS | 19/1243 | 162/23056 | 0.1172840 | 2.175462 | 3.583980 | 0.0011964 | 0.0207486 | 0.0182344 | ABCA12/SGPP2/NEU4/PPM1L/B3GALNT1/SPTSSB/KIT/UGT8/ELOVL2/FUT9/ENPP2/TH/P2RX7/DEGS2/CLN6/ST8SIA2/TLCD3B/SMPD3/ST8SIA3 | 19 |
| GOBP_ANATOMICAL_STRUCTURE_REGRESSION | GOBP_ANATOMICAL_STRUCTURE_REGRESSION | GOBP_ANATOMICAL_STRUCTURE_REGRESSION | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | OPN4/TH/SPI1/DRD2/AMH | 5 |
| GOBP_INHIBITORY_SYNAPSE_ASSEMBLY | GOBP_INHIBITORY_SYNAPSE_ASSEMBLY | GOBP_INHIBITORY_SYNAPSE_ASSEMBLY | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | LHFPL4/GABRG2/GABRB3/CBLN1/CBLN4 | 5 |
| GOBP_NEUROTRANSMITTER_RECEPTOR_TRANSPORT_TO_PLASMA_MEMBRANE | GOBP_NEUROTRANSMITTER_RECEPTOR_TRANSPORT_TO_PLASMA_MEMBRANE | GOBP_NEUROTRANSMITTER_RECEPTOR_TRANSPORT_TO_PLASMA_MEMBRANE | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | GRIP2/CPLX1/NSG1/STX1B/SNAP25 | 5 |
| GOCC_PHOTORECEPTOR_OUTER_SEGMENT_MEMBRANE | GOCC_PHOTORECEPTOR_OUTER_SEGMENT_MEMBRANE | GOCC_PHOTORECEPTOR_OUTER_SEGMENT_MEMBRANE | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | PDE6B/PROM1/CDHR1/GUCY2D/PRCD | 5 |
| GOMF_LIPID_PHOSPHATASE_ACTIVITY | GOMF_LIPID_PHOSPHATASE_ACTIVITY | GOMF_LIPID_PHOSPHATASE_ACTIVITY | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | PLPPR5/PLPPR4/SGPP2/PLPPR1/PLPPR3 | 5 |
| GOMF_POTASSIUM_ION_LEAK_CHANNEL_ACTIVITY | GOMF_POTASSIUM_ION_LEAK_CHANNEL_ACTIVITY | GOMF_POTASSIUM_ION_LEAK_CHANNEL_ACTIVITY | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | KCNK3/KCNK9/KCNK7/KCNK10/KCNK15 | 5 |
| HP_GAZE_EVOKED_HORIZONTAL_NYSTAGMUS | HP_GAZE_EVOKED_HORIZONTAL_NYSTAGMUS | HP_GAZE_EVOKED_HORIZONTAL_NYSTAGMUS | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | PAX7/SYT14/SCN1A/UROC1/GCH1 | 5 |
| HP_NON_CONVULSIVE_STATUS_EPILEPTICUS_WITHOUT_COMA | HP_NON_CONVULSIVE_STATUS_EPILEPTICUS_WITHOUT_COMA | HP_NON_CONVULSIVE_STATUS_EPILEPTICUS_WITHOUT_COMA | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | GABRD/SCN1A/ADGRV1/GABRG2/STX1B | 5 |
| HP_PHOTOSENSITIVE_TONIC_CLONIC_SEIZURE | HP_PHOTOSENSITIVE_TONIC_CLONIC_SEIZURE | HP_PHOTOSENSITIVE_TONIC_CLONIC_SEIZURE | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | GABRD/SCN1A/GABRG2/KCNQ3/STXBP1 | 5 |
| HP_STATUS_EPILEPTICUS_WITH_PROMINENT_MOTOR_SYMPTOMS | HP_STATUS_EPILEPTICUS_WITH_PROMINENT_MOTOR_SYMPTOMS | HP_STATUS_EPILEPTICUS_WITH_PROMINENT_MOTOR_SYMPTOMS | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | SCN1A/GABRG2/STXBP1/PDE2A/VAMP2 | 5 |
| WP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE | WP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE | WP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE | 5/1243 | 16/23056 | 0.3125000 | 5.796460 | 4.581419 | 0.0011972 | 0.0207486 | 0.0182344 | GRM2/GRM6/GRM4/GRM8/GRM5 | 5 |
| HP_INTELLECTUAL_DISABILITY_MILD | HP_INTELLECTUAL_DISABILITY_MILD | HP_INTELLECTUAL_DISABILITY_MILD | 38/1243 | 418/23056 | 0.0909091 | 1.686243 | 3.379928 | 0.0012077 | 0.0209004 | 0.0183678 | NTNG1/NGF/CHRNB2/NTRK1/MYT1L/SOX11/DPYSL5/KIF1A/SATB1/CPLX1/TFAP2B/GRIK2/DLL1/ACTL6B/CHRNA2/CA8/EYA1/STXBP1/GRIN1/DNAJC12/SLC29A3/BRSK2/TH/GRIA4/KCNJ8/TAC3/FGF14/DLK1/RTL1/MAGEL2/CHRNA7/DCC/TCF4/KCNC3/CACNG2/SYN1/GRIA3/L1CAM | 38 |
| GOBP_HINDBRAIN_DEVELOPMENT | GOBP_HINDBRAIN_DEVELOPMENT | GOBP_HINDBRAIN_DEVELOPMENT | 18/1243 | 150/23056 | 0.1200000 | 2.225841 | 3.595551 | 0.0012234 | 0.0211430 | 0.0185810 | PROX1/CTNNA2/CDK5R2/SCN5A/GATA2/DLL1/EN2/KCNC1/CNTN1/FAIM2/ASCL1/ABAT/CBLN1/CDK5R1/SSTR2/BCL2/MAFB/BMP7 | 18 |
| HP_MOTOR_SEIZURE | HP_MOTOR_SEIZURE | HP_MOTOR_SEIZURE | 34/1243 | 362/23056 | 0.0939227 | 1.742141 | 3.397389 | 0.0012347 | 0.0212904 | 0.0187105 | GABRD/NTNG1/CHRNB2/MYT1L/KIF5C/SCN1A/KIF1A/SLC6A1/SATB1/CACNA1D/CPLX1/ADGRV1/GABRG2/PHACTR1/GRIK2/DLL1/ACTL6B/RELN/CHRNA2/KCNQ3/NTRK2/STXBP1/GRIN1/BRSK2/KCNJ11/CUX2/GABRB3/GABRA5/STX1B/TCF4/ATP1A3/CACNG2/NEXMIF/DCX | 34 |
| WANG_MLL_TARGETS | WANG_MLL_TARGETS | WANG_MLL_TARGETS | 29/1243 | 293/23056 | 0.0989761 | 1.835875 | 3.437329 | 0.0012355 | 0.0212904 | 0.0187105 | RGS16/FRZB/MST1R/PPM1L/SFRP2/SELENOP/IL20RA/ESR1/DLL1/PNMA2/CPQ/CDHR1/KIF21A/HOXC10/KCNC2/KCTD12/STXBP6/PELI2/SLC8A3/RTN4RL1/HLF/LAMA1/CCDC68/GNG8/MAFB/JAM2/GPM6B/RPS6KA6/TMEM35A | 29 |
| GOBP_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS | GOBP_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS | GOBP_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS | 9/1243 | 50/23056 | 0.1800000 | 3.338761 | 3.951944 | 0.0012654 | 0.0217757 | 0.0191371 | VSNL1/KLF7/ABCA12/GPR27/ADCY5/GPLD1/RFX6/ADRA2A/BRSK2 | 9 |
| DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | 10/1243 | 60/23056 | 0.1666667 | 3.091445 | 3.872188 | 0.0012841 | 0.0219232 | 0.0192667 | ALK/ANK2/JAKMIP2/PAX5/NEBL/NELL1/IRS2/ABAT/GPM6B/DCX | 10 |
| GOBP_REGULATION_OF_GLUCOSE_IMPORT | GOBP_REGULATION_OF_GLUCOSE_IMPORT | GOBP_REGULATION_OF_GLUCOSE_IMPORT | 10/1243 | 60/23056 | 0.1666667 | 3.091445 | 3.872188 | 0.0012841 | 0.0219232 | 0.0192667 | HK2/KLF15/POU4F2/SORBS1/SLC1A2/FGF19/PLA2G1B/IRS2/ACE/RTN2 | 10 |
| REACTOME_GABA_RECEPTOR_ACTIVATION | REACTOME_GABA_RECEPTOR_ACTIVATION | REACTOME_GABA_RECEPTOR_ACTIVATION | 10/1243 | 60/23056 | 0.1666667 | 3.091445 | 3.872188 | 0.0012841 | 0.0219232 | 0.0192667 | KCNJ9/GNG4/ADCY5/GABRG2/GABRR2/GABRB3/GABRA5/GABRG3/GNG8/KCNJ6 | 10 |
| HP_MALE_SEXUAL_DYSFUNCTION | HP_MALE_SEXUAL_DYSFUNCTION | HP_MALE_SEXUAL_DYSFUNCTION | 12/1243 | 81/23056 | 0.1481481 | 2.747952 | 3.761877 | 0.0012868 | 0.0219232 | 0.0192667 | DNAJC6/IL17RD/PROK2/GUCY1A1/TFR2/FGF17/CDH23/TAC3/DCC/RTN2/PROKR2/ANOS1 | 12 |
| SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | 12/1243 | 81/23056 | 0.1481481 | 2.747952 | 3.761877 | 0.0012868 | 0.0219232 | 0.0192667 | VAV3/GREB1/CXXC4/ESR1/DNAJC12/SLC4A8/DACH1/SERPINA5/SLC27A2/MAPT/CHST8/INPP5J | 12 |
| GOBP_POSITIVE_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 19/1243 | 163/23056 | 0.1165644 | 2.162115 | 3.554283 | 0.0012874 | 0.0219232 | 0.0192667 | NPPA/ATP1B1/RYR2/RGS7/COX17/ANK2/RELN/KCNC1/GAL/KCNC2/NOS1/P2RX7/AKAP6/HSPA2/CALM1/CACNG4/EDN3/CACNG2/NLGN3 | 19 |
| HP_ABNORMAL_FACIAL_EXPRESSION | HP_ABNORMAL_FACIAL_EXPRESSION | HP_ABNORMAL_FACIAL_EXPRESSION | 19/1243 | 163/23056 | 0.1165644 | 2.162115 | 3.554283 | 0.0012874 | 0.0219232 | 0.0192667 | DNAJC6/IRF6/KCNH1/SCN1A/DUX4/GABRG2/KCNQ3/KCNK9/STXBP1/TH/PDE2A/NECTIN1/DLK1/RTL1/MAPT/ASXL3/ATP1A3/JAM2/KCNJ6 | 19 |
| GOBP_DICARBOXYLIC_ACID_TRANSPORT | GOBP_DICARBOXYLIC_ACID_TRANSPORT | GOBP_DICARBOXYLIC_ACID_TRANSPORT | 13/1243 | 92/23056 | 0.1413043 | 2.621008 | 3.718911 | 0.0012884 | 0.0219232 | 0.0192667 | ADORA1/AGXT/GRM2/NTRK2/STXBP1/SLC1A2/SLC22A6/SLC17A8/P2RX7/ABAT/SYT4/SLC1A6/HRH3 | 13 |
| GOBP_EMBRYONIC_ORGAN_MORPHOGENESIS | GOBP_EMBRYONIC_ORGAN_MORPHOGENESIS | GOBP_EMBRYONIC_ORGAN_MORPHOGENESIS | 29/1243 | 294/23056 | 0.0986395 | 1.829631 | 3.417542 | 0.0013020 | 0.0221224 | 0.0194417 | PROX1/RYR2/SOX11/SIX3/HOXD3/FRZB/GATA2/CHRNA9/PDGFRA/HAND2/HAND1/LHFPL5/DLL1/TWIST1/EYA1/PAX5/ROR2/NODAL/CDH23/TH/USH1C/DSCAML1/HOXC4/FOXN4/ATP8A2/GSC/STRC/MAFB/BMP7 | 29 |
| REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS | REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS | REACTOME_RHO_GTPASES_ACTIVATE_IQGAPS | 7/1243 | 32/23056 | 0.2187500 | 4.057522 | 4.131565 | 0.0013344 | 0.0226385 | 0.0198953 | TUBA3E/TUBB2A/TUBB2B/TUBA1A/TUBA3C/CALM1/TUBB4A | 7 |
| GOMF_GTPASE_ACTIVITY | GOMF_GTPASE_ACTIVITY | GOMF_GTPASE_ACTIVITY | 32/1243 | 336/23056 | 0.0952381 | 1.766540 | 3.378787 | 0.0013503 | 0.0226385 | 0.0198953 | RAP1GAP/ABCA4/RGS5/RGS16/RGS8/RGS13/RGS7/TUBA3E/ARL6/RASL11B/RAB3C/TUBB2A/TUBB2B/RAB19/RASEF/DIRAS2/RAB39A/RERG/TUBA1A/TUBA3C/GCH1/RGS11/RNF112/RIT2/TUBB4A/RAB3A/GNG8/SEPTIN5/SEPTIN3/ERAS/SEPTIN6/RAB39B | 32 |
| HP_BILATERAL_POLYMICROGYRIA | HP_BILATERAL_POLYMICROGYRIA | HP_BILATERAL_POLYMICROGYRIA | 8/1243 | 41/23056 | 0.1951220 | 3.619253 | 4.007046 | 0.0013564 | 0.0226385 | 0.0198953 | MYT1L/KIF1A/DLL1/STXBP1/GRIN1/BRSK2/TCF4/CACNG2 | 8 |
| MIKKELSEN_ES_HCP_WITH_H3K27ME3 | MIKKELSEN_ES_HCP_WITH_H3K27ME3 | MIKKELSEN_ES_HCP_WITH_H3K27ME3 | 8/1243 | 41/23056 | 0.1951220 | 3.619253 | 4.007046 | 0.0013564 | 0.0226385 | 0.0198953 | TAL1/HOXD8/SLITRK3/PCDHB11/KCNIP1/TFAP2B/DCC/MPPED1 | 8 |
| GOBP_CARDIAC_VENTRICLE_FORMATION | GOBP_CARDIAC_VENTRICLE_FORMATION | GOBP_CARDIAC_VENTRICLE_FORMATION | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | SOX11/HAND2/HAND1/SOX4 | 4 |
| GOBP_PONS_DEVELOPMENT | GOBP_PONS_DEVELOPMENT | GOBP_PONS_DEVELOPMENT | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | CDK5R2/ASCL1/CDK5R1/BCL2 | 4 |
| GOBP_RETROGRADE_TRANS_SYNAPTIC_SIGNALING | GOBP_RETROGRADE_TRANS_SYNAPTIC_SIGNALING | GOBP_RETROGRADE_TRANS_SYNAPTIC_SIGNALING | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | GUCY1A1/CNR1/NOS1/SYT4 | 4 |
| GOBP_SYNAPTIC_VESICLE_DOCKING | GOBP_SYNAPTIC_VESICLE_DOCKING | GOBP_SYNAPTIC_VESICLE_DOCKING | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | STX1B/UNC13A/PPFIA3/SNAP25 | 4 |
| GOCC_SYMMETRIC_SYNAPSE | GOCC_SYMMETRIC_SYNAPSE | GOCC_SYMMETRIC_SYNAPSE | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | IQSEC3/SLC4A8/NLGN3/NLGN4Y | 4 |
| GOMF_NEUROPEPTIDE_Y_RECEPTOR_ACTIVITY | GOMF_NEUROPEPTIDE_Y_RECEPTOR_ACTIVITY | GOMF_NEUROPEPTIDE_Y_RECEPTOR_ACTIVITY | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | PROKR1/NPY2R/PRLHR/PROKR2 | 4 |
| HP_LACK_OF_PEER_RELATIONSHIPS | HP_LACK_OF_PEER_RELATIONSHIPS | HP_LACK_OF_PEER_RELATIONSHIPS | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | SCN1A/SLC6A1/NLGN3/NEXMIF | 4 |
| REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | GRIK3/GRIK2/GRIK4/CALM1 | 4 |
| SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN | SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN | SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN | 4/1243 | 10/23056 | 0.4000000 | 7.419469 | 4.846874 | 0.0013583 | 0.0226385 | 0.0198953 | CPB1/ELOVL2/DNAJC12/ARNT2 | 4 |
| GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 25/1243 | 241/23056 | 0.1037344 | 1.924136 | 3.442664 | 0.0013584 | 0.0226385 | 0.0198953 | SLC6A17/SLC8A1/SLC6A11/SLC6A1/SLC38A3/SLC10A4/SLC16A10/SLC35D3/SLC18A1/SLC24A2/SLC6A5/SLC1A2/SLC22A6/SLCO1B1/SLC4A8/SLC6A15/SLC17A8/SLC8A3/SLC6A2/SLC4A1/SLC1A6/ATP1A3/SLC8A2/SLC32A1/SLC37A1 | 25 |
| GOBP_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 14/1243 | 104/23056 | 0.1346154 | 2.496937 | 3.652332 | 0.0013804 | 0.0229727 | 0.0201890 | OPRD1/PTGER3/GPR27/AGTR1/ESR1/VIP/OPRM1/ADRA2A/CHRM1/GRM5/DRD2/CHGA/GPR139/P2RY11 | 14 |
| CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 30/1243 | 309/23056 | 0.0970874 | 1.800842 | 3.383175 | 0.0013931 | 0.0231312 | 0.0203282 | GRIK3/AK4/MEX3A/ADORA1/GREB1/FGFBP2/SAP30/F12/TUBB2B/ELOVL2/PKIB/MYB/PI15/FGD3/OLFM1/AFAP1L2/ATRNL1/MPPED2/RERG/CCNA1/IRS2/NRXN3/SERPINA5/SLC27A2/ABAT/MAPT/SSTR2/BCL2/PLIN5/ARHGAP36 | 30 |
| GOBP_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY | 11/1243 | 71/23056 | 0.1549296 | 2.873738 | 3.774646 | 0.0013937 | 0.0231312 | 0.0203282 | NPPA/ANK2/RELN/KCNC1/GAL/KCNC2/AKAP6/CALM1/CACNG4/CACNG2/NLGN3 | 11 |
| GOBP_DETECTION_OF_TEMPERATURE_STIMULUS | GOBP_DETECTION_OF_TEMPERATURE_STIMULUS | GOBP_DETECTION_OF_TEMPERATURE_STIMULUS | 6/1243 | 24/23056 | 0.2500000 | 4.637168 | 4.255627 | 0.0014103 | 0.0233754 | 0.0205429 | NTRK1/ADORA1/CXCR4/GRIK2/DRGX/OPN4 | 6 |
| GOMF_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_INORGANIC_ANION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 18/1243 | 152/23056 | 0.1184211 | 2.196553 | 3.533122 | 0.0014243 | 0.0235602 | 0.0207053 | GABRD/SLC6A1/GABRG1/GLRA3/GABRG2/GABRP/GABRR2/CLCN1/SLC18A1/ANO5/SLC22A6/SLC4A8/GABRB3/GABRA5/GABRG3/SLC6A2/SLC4A1/SLC37A1 | 18 |
| GOBP_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | GOBP_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | GOBP_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION | 13/1243 | 93/23056 | 0.1397849 | 2.592825 | 3.674140 | 0.0014254 | 0.0235602 | 0.0207053 | ADORA1/VSNL1/MYRIP/GPR27/ISL1/SOX4/GPLD1/RFX6/TFR2/DRD2/IRS2/ABAT/DOC2B | 13 |
| GOBP_PRESYNAPTIC_ENDOCYTOSIS | GOBP_PRESYNAPTIC_ENDOCYTOSIS | GOBP_PRESYNAPTIC_ENDOCYTOSIS | 10/1243 | 61/23056 | 0.1639344 | 3.040766 | 3.809797 | 0.0014629 | 0.0240513 | 0.0211369 | DNAJC6/SNCB/PACSIN1/SNAP91/SYT8/VAMP2/SYT5/SYP/NLGN3/NLGN4Y | 10 |
| GOMF_PHOSPHATIDYLSERINE_BINDING | GOMF_PHOSPHATIDYLSERINE_BINDING | GOMF_PHOSPHATIDYLSERINE_BINDING | 10/1243 | 61/23056 | 0.1639344 | 3.040766 | 3.809797 | 0.0014629 | 0.0240513 | 0.0211369 | SYT11/GAP43/SYT8/SYT13/SYT7/SMPD3/SYT4/SYT3/SYT5/RS1 | 10 |
| REACTOME_KINESINS | REACTOME_KINESINS | REACTOME_KINESINS | 10/1243 | 61/23056 | 0.1639344 | 3.040766 | 3.809797 | 0.0014629 | 0.0240513 | 0.0211369 | KIF3C/TUBA3E/KIF1A/TUBB2A/TUBB2B/KIF21A/TUBA1A/KIF5A/TUBA3C/TUBB4A | 10 |
| GOBP_POSITIVE_REGULATION_OF_OSSIFICATION | GOBP_POSITIVE_REGULATION_OF_OSSIFICATION | GOBP_POSITIVE_REGULATION_OF_OSSIFICATION | 9/1243 | 51/23056 | 0.1764706 | 3.273295 | 3.879629 | 0.0014642 | 0.0240513 | 0.0211369 | SOX11/SLC8A1/BMPR1B/ADGRV1/NELL1/P2RX7/KL/BMP7/GPM6B | 9 |
| GOCC_CELL_CORTEX | GOCC_CELL_CORTEX | GOCC_CELL_CORTEX | 30/1243 | 310/23056 | 0.0967742 | 1.795033 | 3.364138 | 0.0014650 | 0.0240513 | 0.0211369 | PRKCZ/RIMS3/KIAA1614/MYRIP/BSN/ERC2/HCLS1/BFSP2/SPINK5/RIMS1/DMTN/CALB1/TMOD1/INSC/ENO2/CABP1/STXBP6/EXOC3L1/PARD6A/SLC4A1/TLE6/RASAL3/UNC13A/PPFIA3/KCNC3/SEPTIN5/SEPTIN3/SHROOM4/SEPTIN6/PDZD4 | 30 |
| GOBP_NEURON_DEATH | GOBP_NEURON_DEATH | GOBP_NEURON_DEATH | 33/1243 | 352/23056 | 0.0937500 | 1.738938 | 3.334944 | 0.0014886 | 0.0244064 | 0.0214490 | NGF/NTRK1/ADORA1/CHL1/CD200/ISL1/SNCB/GRM4/TFAP2D/TFAP2B/GRIK2/FYN/NPY/EN2/NTRK2/STXBP1/ENO2/FAIM2/ASCL1/CHGA/DIO3/GABRA5/CHRNA7/ST8SIA2/CDK5R1/MAPT/DCC/BCL2/PRKCG/VSTM2L/ITGB2/PLA2G3/PAK3 | 33 |
| HP_ABNORMAL_FEAR_ANXIETY_RELATED_BEHAVIOR | HP_ABNORMAL_FEAR_ANXIETY_RELATED_BEHAVIOR | HP_ABNORMAL_FEAR_ANXIETY_RELATED_BEHAVIOR | 37/1243 | 409/23056 | 0.0904645 | 1.677997 | 3.302514 | 0.0015158 | 0.0248179 | 0.0218106 | GABRD/DNAJC6/NTNG1/CHRNB2/NFASC/MYT1L/DPYSL5/SIX3/SCN1A/SATB1/PROK2/ADCY5/ADGRV1/GABRG2/DLL1/ACTL6B/FGF17/CHRNA2/STXBP1/NODAL/CDH23/USH1C/GRIA4/DRD2/TAC3/PAH/GCH1/GABRB3/STX1B/JPH3/MAPT/UNC13A/ATP1A3/PROKR2/NEFH/NEXMIF/PAK3 | 37 |
| HP_ABNORMAL_ORAL_PHYSIOLOGY | HP_ABNORMAL_ORAL_PHYSIOLOGY | HP_ABNORMAL_ORAL_PHYSIOLOGY | 25/1243 | 243/23056 | 0.1028807 | 1.908300 | 3.397829 | 0.0015244 | 0.0249263 | 0.0219058 | IRF6/CHRM3/NRXN1/SCN1A/WNT10A/SATB1/GABRG2/TUBB2B/STXBP1/GRIN1/TH/NECTIN1/GCH1/DLK1/RTL1/MAGEL2/UNC13A/ATP1A3/NEFH/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/RAB39B | 25 |
| GOBP_HORMONE_METABOLIC_PROCESS | GOBP_HORMONE_METABOLIC_PROCESS | GOBP_HORMONE_METABOLIC_PROCESS | 24/1243 | 230/23056 | 0.1043478 | 1.935514 | 3.403765 | 0.0015476 | 0.0252717 | 0.0222094 | TPO/RBP1/CPA3/BCHE/ECE2/PDGFRA/ADH4/SLC16A10/ESR1/CPQ/ALDH1A1/PRLHR/GAL/DHRS2/DIO3/DUOXA1/DUOX1/CRABP1/ACE/CHST9/CHST8/ASMT/PNPLA4/PCSK1N | 24 |
| GOBP_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | 15/1243 | 117/23056 | 0.1282051 | 2.378035 | 3.567191 | 0.0015640 | 0.0255052 | 0.0224146 | NPPA/ATP1B1/RYR2/COX17/ANK2/RELN/KCNC1/GAL/KCNC2/AKAP6/HSPA2/CALM1/CACNG4/CACNG2/NLGN3 | 15 |
| HP_ABNORMAL_CONSUMPTION_BEHAVIOR | HP_ABNORMAL_CONSUMPTION_BEHAVIOR | HP_ABNORMAL_CONSUMPTION_BEHAVIOR | 17/1243 | 141/23056 | 0.1205674 | 2.236365 | 3.515254 | 0.0015671 | 0.0255208 | 0.0224283 | GABRD/PRKCZ/SOX11/CACNA1D/SOX2/SOX4/PKHD1/NTRK2/CHAT/KCNJ11/MAGEL2/ARNT2/MAPT/MC4R/PROKR2/SNAP25/NEXMIF | 17 |
| KEGG_AXON_GUIDANCE | KEGG_AXON_GUIDANCE | KEGG_AXON_GUIDANCE | 16/1243 | 129/23056 | 0.1240310 | 2.300611 | 3.536136 | 0.0015789 | 0.0256788 | 0.0225672 | EPHA8/NTNG1/DPYSL5/CXCR4/EPHA6/SEMA5B/UNC5C/UNC5A/FYN/DPYSL2/SLIT1/LRRC4C/DCC/PAK5/PAK3/L1CAM | 16 |
| GOBP_POSITIVE_REGULATION_OF_BONE_MINERALIZATION | GOBP_POSITIVE_REGULATION_OF_BONE_MINERALIZATION | GOBP_POSITIVE_REGULATION_OF_BONE_MINERALIZATION | 8/1243 | 42/23056 | 0.1904762 | 3.533081 | 3.922275 | 0.0015976 | 0.0257811 | 0.0226571 | SLC8A1/BMPR1B/ADGRV1/NELL1/P2RX7/KL/BMP7/GPM6B | 8 |
| HP_FOCAL_EMOTIONAL_SEIZURE | HP_FOCAL_EMOTIONAL_SEIZURE | HP_FOCAL_EMOTIONAL_SEIZURE | 8/1243 | 42/23056 | 0.1904762 | 3.533081 | 3.922275 | 0.0015976 | 0.0257811 | 0.0226571 | MYT1L/KIF1A/DLL1/STXBP1/GRIN1/BRSK2/TCF4/CACNG2 | 8 |
| REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | 8/1243 | 42/23056 | 0.1904762 | 3.533081 | 3.922275 | 0.0015976 | 0.0257811 | 0.0226571 | HTR6/CHRM3/HRH2/HTR1E/ADRA2A/CHRM1/DRD2/HRH3 | 8 |
| GOBP_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | 7/1243 | 33/23056 | 0.2121212 | 3.934567 | 4.026989 | 0.0016158 | 0.0257811 | 0.0226571 | ATP1B1/SCN5A/FGF12/SCN4B/SCN3B/CNTN1/NOS1 | 7 |
| GOMF_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY | GOMF_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY | GOMF_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY | 7/1243 | 33/23056 | 0.2121212 | 3.934567 | 4.026989 | 0.0016158 | 0.0257811 | 0.0226571 | KCNA3/KCNH1/KCNB2/KCNQ3/KCNC1/KCNC2/KCNC3 | 7 |
| HP_DISTURBANCE_OF_FACIAL_EXPRESSION | HP_DISTURBANCE_OF_FACIAL_EXPRESSION | HP_DISTURBANCE_OF_FACIAL_EXPRESSION | 7/1243 | 33/23056 | 0.2121212 | 3.934567 | 4.026989 | 0.0016158 | 0.0257811 | 0.0226571 | IRF6/SCN1A/GABRG2/KCNQ3/STXBP1/PDE2A/NECTIN1 | 7 |
| WP_MONOAMINE_GPCRS | WP_MONOAMINE_GPCRS | WP_MONOAMINE_GPCRS | 7/1243 | 33/23056 | 0.2121212 | 3.934567 | 4.026989 | 0.0016158 | 0.0257811 | 0.0226571 | HTR6/CHRM3/HRH2/HTR1E/ADRA2A/CHRM1/DRD2 | 7 |
| GOBP_DENDRITE_SELF_AVOIDANCE | GOBP_DENDRITE_SELF_AVOIDANCE | GOBP_DENDRITE_SELF_AVOIDANCE | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | CNTN2/CNTN6/CNTN4/DSCAML1/VSTM2L | 5 |
| GOBP_GAMMA_AMINOBUTYRIC_ACID_TRANSPORT | GOBP_GAMMA_AMINOBUTYRIC_ACID_TRANSPORT | GOBP_GAMMA_AMINOBUTYRIC_ACID_TRANSPORT | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | SLC6A11/SLC6A1/P2RX7/ABAT/SLC32A1 | 5 |
| GOBP_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | ELAVL4/ALK/PACSIN1/BMP7/ZDHHC15 | 5 |
| GOBP_RELAXATION_OF_CARDIAC_MUSCLE | GOBP_RELAXATION_OF_CARDIAC_MUSCLE | GOBP_RELAXATION_OF_CARDIAC_MUSCLE | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | PDE4B/ATP1B1/SLC8A1/CHGA/HRC | 5 |
| GOBP_STABILIZATION_OF_MEMBRANE_POTENTIAL | GOBP_STABILIZATION_OF_MEMBRANE_POTENTIAL | GOBP_STABILIZATION_OF_MEMBRANE_POTENTIAL | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | KCNK3/KCNK9/KCNK7/KCNK10/KCNK15 | 5 |
| GOCC_INTRINSIC_COMPONENT_OF_PRESYNAPTIC_ACTIVE_ZONE_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_PRESYNAPTIC_ACTIVE_ZONE_MEMBRANE | GOCC_INTRINSIC_COMPONENT_OF_PRESYNAPTIC_ACTIVE_ZONE_MEMBRANE | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | NTNG1/ATP2B2/ADRA2A/NECTIN1/CPLX3 | 5 |
| GOMF_GABA_RECEPTOR_BINDING | GOMF_GABA_RECEPTOR_BINDING | GOMF_GABA_RECEPTOR_BINDING | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | LHFPL4/PLCL2/GABRG1/GABRA5/SHISA7 | 5 |
| HP_COMPENSATORY_HEAD_POSTURE | HP_COMPENSATORY_HEAD_POSTURE | HP_COMPENSATORY_HEAD_POSTURE | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | PDE6B/GRM6/KIF21A/GRK1/CACNA1F | 5 |
| HP_TALIPES_VALGUS | HP_TALIPES_VALGUS | HP_TALIPES_VALGUS | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | GABRD/SCN1A/ADGRV1/GABRG2/STX1B | 5 |
| REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | 5/1243 | 17/23056 | 0.2941176 | 5.455492 | 4.386809 | 0.0016213 | 0.0257811 | 0.0226571 | GRIP2/GRIA4/PRKCG/TSPAN7/GRIA3 | 5 |
| GOMF_PEPTIDE_RECEPTOR_ACTIVITY | GOMF_PEPTIDE_RECEPTOR_ACTIVITY | GOMF_PEPTIDE_RECEPTOR_ACTIVITY | 18/1243 | 154/23056 | 0.1168831 | 2.168027 | 3.471657 | 0.0016524 | 0.0262421 | 0.0230622 | OPRD1/HCRTR1/PROKR1/CXCR4/AGTR1/NPY2R/GLP1R/OPRM1/ADCYAP1R1/VIPR2/SORCS3/PRLHR/GAL/GPR139/GUCY2D/SSTR2/MC4R/PROKR2 | 18 |
| MASSARWEH_RESPONSE_TO_ESTRADIOL | MASSARWEH_RESPONSE_TO_ESTRADIOL | MASSARWEH_RESPONSE_TO_ESTRADIOL | 10/1243 | 62/23056 | 0.1612903 | 2.991721 | 3.748673 | 0.0016614 | 0.0263167 | 0.0231278 | GREB1/MAP2/TUBB2B/ELOVL2/SOX4/MYB/OLFM1/ADRA2A/SERPINA5/MAPT | 10 |
| WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | 10/1243 | 62/23056 | 0.1612903 | 2.991721 | 3.748673 | 0.0016614 | 0.0263167 | 0.0231278 | TPO/CXCR4/HES6/GATA2/MYB/MXI1/SPI1/TRIM29/KLF1/ZNF835 | 10 |
| GOBP_RETINA_LAYER_FORMATION | GOBP_RETINA_LAYER_FORMATION | GOBP_RETINA_LAYER_FORMATION | 6/1243 | 25/23056 | 0.2400000 | 4.451681 | 4.121969 | 0.0017720 | 0.0279739 | 0.0245842 | PROM1/TFAP2B/CALB1/FOXN4/ATP8A2/RS1 | 6 |
| GOBP_SYNAPTIC_MEMBRANE_ADHESION | GOBP_SYNAPTIC_MEMBRANE_ADHESION | GOBP_SYNAPTIC_MEMBRANE_ADHESION | 6/1243 | 25/23056 | 0.2400000 | 4.451681 | 4.121969 | 0.0017720 | 0.0279739 | 0.0245842 | NTNG1/SLITRK3/LRRC4C/PCDH8/PCDH17/SLITRK1 | 6 |
| HP_DILATION_OF_LATERAL_VENTRICLES | HP_DILATION_OF_LATERAL_VENTRICLES | HP_DILATION_OF_LATERAL_VENTRICLES | 12/1243 | 84/23056 | 0.1428571 | 2.649810 | 3.616052 | 0.0017733 | 0.0279739 | 0.0245842 | MYT1L/KIF1A/SATB1/TUBB2B/DLL1/STXBP1/GRIN1/BRSK2/ASXL3/TCF4/CACNG2/DCX | 12 |
| GOBP_CELLULAR_GLUCOSE_HOMEOSTASIS | GOBP_CELLULAR_GLUCOSE_HOMEOSTASIS | GOBP_CELLULAR_GLUCOSE_HOMEOSTASIS | 18/1243 | 155/23056 | 0.1161290 | 2.154039 | 3.441277 | 0.0017776 | 0.0279739 | 0.0245842 | VSNL1/HK2/KLF7/ABCA12/PTPRN/GPR27/ADCY5/KLF15/HK3/SOX4/GPLD1/RFX6/PTPRN2/ADRA2A/BRSK2/TH/IRS2/ACE | 18 |
| GOBP_PROTEIN_CONTAINING_COMPLEX_LOCALIZATION | GOBP_PROTEIN_CONTAINING_COMPLEX_LOCALIZATION | GOBP_PROTEIN_CONTAINING_COMPLEX_LOCALIZATION | 18/1243 | 155/23056 | 0.1161290 | 2.154039 | 3.441277 | 0.0017776 | 0.0279739 | 0.0245842 | PRKCZ/HPCA/LRRC7/KIF5C/GRIP2/CPLX1/NSG1/RELN/CNIH2/KIF5A/GSG1L/STX1B/EXOC3L1/CACNG5/CACNG4/CACNG7/SNAP25/CACNG2 | 18 |
| GOBP_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 14/1243 | 107/23056 | 0.1308411 | 2.426929 | 3.531611 | 0.0018185 | 0.0285813 | 0.0251180 | GATA2/KIT/CPLX2/SERPINB9/SYK/STXBP1/SPI1/PLA2G1B/CHGA/VAMP2/ACE/ITGB2/PLA2G3/IL13RA2 | 14 |
| HP_AGGRESSIVE_BEHAVIOR | HP_AGGRESSIVE_BEHAVIOR | HP_AGGRESSIVE_BEHAVIOR | 24/1243 | 233/23056 | 0.1030043 | 1.910593 | 3.334850 | 0.0018426 | 0.0289217 | 0.0254171 | GABRD/SLC6A17/NFASC/MYT1L/SOX11/DPYSL5/SCN1A/UROC1/SOX4/CNTNAP2/KCNQ3/PDE2A/PAH/CUX2/SLITRK1/FGF14/GABRB3/MAPT/TCF4/ATP1A3/SYN1/NEXMIF/PAK3/GRIA3 | 24 |
| HP_SEVERE_GLOBAL_DEVELOPMENTAL_DELAY | HP_SEVERE_GLOBAL_DEVELOPMENTAL_DELAY | HP_SEVERE_GLOBAL_DEVELOPMENTAL_DELAY | 23/1243 | 220/23056 | 0.1045455 | 1.939179 | 3.341260 | 0.0018697 | 0.0291854 | 0.0256489 | NTNG1/KCNH1/MYT1L/DPYSL5/CTNNA2/UNC80/SATB1/CTNND2/GABRG2/TUBB2A/PHACTR1/ACTL6B/RELN/NTRK2/STXBP1/GRIN1/GRIA4/DLK1/RTL1/ARNT2/ASXL3/KCNJ6/NEXMIF | 23 |
| GOBP_PHOTORECEPTOR_CELL_MAINTENANCE | GOBP_PHOTORECEPTOR_CELL_MAINTENANCE | GOBP_PHOTORECEPTOR_CELL_MAINTENANCE | 8/1243 | 43/23056 | 0.1860465 | 3.450916 | 3.840046 | 0.0018714 | 0.0291854 | 0.0256489 | ABCA4/PROM1/ADGRV1/RP1L1/CDH23/CDHR1/USH1C/CNGB1 | 8 |
| HP_EEG_WITH_POLYSPIKE_WAVE_COMPLEXES | HP_EEG_WITH_POLYSPIKE_WAVE_COMPLEXES | HP_EEG_WITH_POLYSPIKE_WAVE_COMPLEXES | 8/1243 | 43/23056 | 0.1860465 | 3.450916 | 3.840046 | 0.0018714 | 0.0291854 | 0.0256489 | GABRD/SCN1A/SLC6A1/GABRG2/KCNQ3/CHAT/SNAP25/NEXMIF | 8 |
| HUMMEL_BURKITTS_LYMPHOMA_UP | HUMMEL_BURKITTS_LYMPHOMA_UP | HUMMEL_BURKITTS_LYMPHOMA_UP | 8/1243 | 43/23056 | 0.1860465 | 3.450916 | 3.840046 | 0.0018714 | 0.0291854 | 0.0256489 | SOX11/NSG1/TUBB2A/TUBB2B/BACH2/LZTS1/TUBA1A/BMP7 | 8 |
| ULE_SPLICING_VIA_NOVA2 | ULE_SPLICING_VIA_NOVA2 | ULE_SPLICING_VIA_NOVA2 | 8/1243 | 43/23056 | 0.1860465 | 3.450916 | 3.840046 | 0.0018714 | 0.0291854 | 0.0256489 | RAP1GAP/NTNG1/CTNNA2/CHL1/GRIK2/GRIN1/CACNA1B/MAPK8IP1 | 8 |
| GOBP_NEURON_FATE_COMMITMENT | GOBP_NEURON_FATE_COMMITMENT | GOBP_NEURON_FATE_COMMITMENT | 10/1243 | 63/23056 | 0.1587302 | 2.944234 | 3.688768 | 0.0018813 | 0.0293018 | 0.0257511 | MYT1L/FEV/GATA2/ISL1/POU3F2/DLL1/EYA1/HOXC10/ASCL1/FOXN4 | 10 |
| HP_AUTISM | HP_AUTISM | HP_AUTISM | 22/1243 | 207/23056 | 0.1062802 | 1.971356 | 3.351125 | 0.0018853 | 0.0293115 | 0.0257597 | GABRD/PRKCZ/SCN3A/SATB1/SOX2/FGF12/GABRG2/ACTL6B/NTRK2/STXBP1/CACNA1B/CELF2/SLC1A2/PAH/MAGEL2/GABRA5/CHRNA7/ARNT2/ASXL3/PROKR2/NLGN3/GRIA3 | 22 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | 21/1243 | 194/23056 | 0.1082474 | 2.007846 | 3.365103 | 0.0018867 | 0.0293115 | 0.0257597 | DNAJC6/OLFM3/CMPK2/RSAD2/SLC8A1/MEIS1/OSBPL6/KIT/SOX4/DEFB1/DUSP4/CALB1/ALDH1A1/CDKN1C/C11orf96/SCN4B/STXBP6/TDRD9/PLD4/LAMP5/ZNF711 | 21 |
| GOBP_PLASMA_MEMBRANE_ORGANIZATION | GOBP_PLASMA_MEMBRANE_ORGANIZATION | GOBP_PLASMA_MEMBRANE_ORGANIZATION | 18/1243 | 156/23056 | 0.1153846 | 2.140231 | 3.411128 | 0.0019106 | 0.0296456 | 0.0260533 | SYT11/OTOF/DYSF/CXCR4/ROPN1B/PLSCR5/ANK2/PACSIN1/XKR5/MTSS1/MYMK/SYT7/ABCD2/P2RX7/SERPINA5/SLC4A1/RAB3A/XKR7 | 18 |
| GOBP_REGULATION_OF_CYCLASE_ACTIVITY | GOBP_REGULATION_OF_CYCLASE_ACTIVITY | GOBP_REGULATION_OF_CYCLASE_ACTIVITY | 9/1243 | 53/23056 | 0.1698113 | 3.149775 | 3.740236 | 0.0019370 | 0.0300063 | 0.0263703 | HPCA/RD3/GRM2/CACNA1D/ADGRV1/GUCA1A/DRD2/NOS1/CALM1 | 9 |
| MIKKELSEN_MCV6_ICP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_MCV6_ICP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_MCV6_ICP_WITH_H3K4ME3_AND_H3K27ME3 | 7/1243 | 34/23056 | 0.2058824 | 3.818844 | 3.926445 | 0.0019413 | 0.0300063 | 0.0263703 | SUSD4/NCKAP5/CFAP65/NPY2R/SCML4/RLN1/SYT3 | 7 |
| REACTOME_THE_PHOTOTRANSDUCTION_CASCADE | REACTOME_THE_PHOTOTRANSDUCTION_CASCADE | REACTOME_THE_PHOTOTRANSDUCTION_CASCADE | 7/1243 | 34/23056 | 0.2058824 | 3.818844 | 3.926445 | 0.0019413 | 0.0300063 | 0.0263703 | PDE6B/GUCA1A/GRK1/CALM1/CNGB1/GUCY2D/PPEF1 | 7 |
| SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | 12/1243 | 85/23056 | 0.1411765 | 2.618636 | 3.568857 | 0.0019656 | 0.0302969 | 0.0266256 | VAV3/KIAA0040/PROM1/ZDHHC11/MYB/IL20RA/RAPGEF5/DEFB1/DNAJC12/SHANK2/SLC27A2/ABAT | 12 |
| HP_DECREASED_TESTICULAR_SIZE | HP_DECREASED_TESTICULAR_SIZE | HP_DECREASED_TESTICULAR_SIZE | 17/1243 | 144/23056 | 0.1180556 | 2.189774 | 3.418807 | 0.0019701 | 0.0302969 | 0.0266256 | CHRM3/IL17RD/PROK2/ARL6/FGF17/SLC29A3/CDKN1C/TAC3/TDRD9/MAGEL2/TEX14/DCC/PROKR2/KCNJ6/ANOS1/NR0B1/DAZ4 | 17 |
| REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | 17/1243 | 144/23056 | 0.1180556 | 2.189774 | 3.418807 | 0.0019701 | 0.0302969 | 0.0266256 | HTR6/GNG4/PDE1A/GPR27/ADCY5/HRH2/GLP1R/VIP/ADCYAP1R1/VIPR2/RLN2/CALCB/PDE2A/MC4R/P2RY11/GNG8/GRK3 | 17 |
| WP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING_PATHWAY | WP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING_PATHWAY | WP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING_PATHWAY | 17/1243 | 144/23056 | 0.1180556 | 2.189774 | 3.418807 | 0.0019701 | 0.0302969 | 0.0266256 | VAV3/KCNA3/NGF/NTRK1/CNR1/FYN/DPYSL2/NTRK2/GRIN1/IRS2/GABRB3/CDK5R1/MAPT/RAB3A/TIAM1/SYN1/GRIA3 | 17 |
| GOBP_REGULATION_OF_EXTENT_OF_CELL_GROWTH | GOBP_REGULATION_OF_EXTENT_OF_CELL_GROWTH | GOBP_REGULATION_OF_EXTENT_OF_CELL_GROWTH | 14/1243 | 108/23056 | 0.1296296 | 2.404458 | 3.492276 | 0.0019880 | 0.0304571 | 0.0267665 | NGF/TNR/MAP2/SEMA5B/POU4F2/FSTL4/DPYSL2/OLFM1/SLIT1/ISLR2/CDK5R1/MAPT/DCC/L1CAM | 14 |
| HP_SMALL_HAND | HP_SMALL_HAND | HP_SMALL_HAND | 14/1243 | 108/23056 | 0.1296296 | 2.404458 | 3.492276 | 0.0019880 | 0.0304571 | 0.0267665 | NTNG1/SLC6A17/KIF5C/UNC80/SATB1/CTNND2/ROR2/STXBP1/DLK1/RTL1/MAGEL2/MCTP2/TCF4/SHROOM4 | 14 |
| HP_SYNCOPE | HP_SYNCOPE | HP_SYNCOPE | 14/1243 | 108/23056 | 0.1296296 | 2.404458 | 3.492276 | 0.0019880 | 0.0304571 | 0.0267665 | NPPA/NTRK1/RYR2/SCN5A/KIT/ANK2/DBH/KCNJ11/SCN4B/SCN3B/KCNJ8/CALM1/DSC2/P2RY11 | 14 |
| GOBP_IMPORT_ACROSS_PLASMA_MEMBRANE | GOBP_IMPORT_ACROSS_PLASMA_MEMBRANE | GOBP_IMPORT_ACROSS_PLASMA_MEMBRANE | 20/1243 | 182/23056 | 0.1098901 | 2.038316 | 3.357024 | 0.0019985 | 0.0305787 | 0.0268733 | KCNJ9/ATP1B1/SLC8A1/SLC6A1/ACSL1/FYN/KCNK9/SLC24A2/KCNJ11/SLC6A5/SLC1A2/KCNJ8/IRS2/SLC8A3/SLC1A6/ATP4A/ATP1A3/SLC8A2/KCNJ6/SLC7A3 | 20 |
| HP_ABNORMAL_AUTONOMIC_NERVOUS_SYSTEM_PHYSIOLOGY | HP_ABNORMAL_AUTONOMIC_NERVOUS_SYSTEM_PHYSIOLOGY | HP_ABNORMAL_AUTONOMIC_NERVOUS_SYSTEM_PHYSIOLOGY | 15/1243 | 120/23056 | 0.1250000 | 2.318584 | 3.457005 | 0.0020171 | 0.0307298 | 0.0270061 | DNAJC6/NTRK1/SCN3A/SCN5A/ANK2/RELN/DBH/SCN4B/ASCL1/CALM1/CHRNA3/SLC6A2/MAPT/TCF4/ATP1A3 | 15 |
| BILD_E2F3_ONCOGENIC_SIGNATURE | BILD_E2F3_ONCOGENIC_SIGNATURE | BILD_E2F3_ONCOGENIC_SIGNATURE | 25/1243 | 248/23056 | 0.1008065 | 1.869826 | 3.287570 | 0.0020175 | 0.0307298 | 0.0270061 | MANEAL/AK4/CMPK2/EML6/PLCL2/GPR27/NSG1/UGT8/UBE2QL1/FAXC/MYB/ARFGEF3/FAM95C/RASEF/EPB41L4B/STXBP1/ATRNL1/CDKN1C/CHST1/ENO2/HRK/GCH1/TM6SF1/SBK1/TIAM1 | 25 |
| GOBP_NEUROTRANSMITTER_CATABOLIC_PROCESS | GOBP_NEUROTRANSMITTER_CATABOLIC_PROCESS | GOBP_NEUROTRANSMITTER_CATABOLIC_PROCESS | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | BCHE/PRIMA1/ABAT/MAOB | 4 |
| GOBP_NORADRENERGIC_NEURON_DIFFERENTIATION | GOBP_NORADRENERGIC_NEURON_DIFFERENTIATION | GOBP_NORADRENERGIC_NEURON_DIFFERENTIATION | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | SOX11/HAND2/SOX4/ASCL1 | 4 |
| GOBP_POSITIVE_REGULATION_OF_FATTY_ACID_BETA_OXIDATION | GOBP_POSITIVE_REGULATION_OF_FATTY_ACID_BETA_OXIDATION | GOBP_POSITIVE_REGULATION_OF_FATTY_ACID_BETA_OXIDATION | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | TWIST1/ABCD2/IRS2/PLIN5 | 4 |
| GOBP_POSTSYNAPTIC_MEMBRANE_ASSEMBLY | GOBP_POSTSYNAPTIC_MEMBRANE_ASSEMBLY | GOBP_POSTSYNAPTIC_MEMBRANE_ASSEMBLY | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | NRXN1/NRXN2/NLGN3/NLGN4Y | 4 |
| GOBP_REGULATION_OF_AXON_GUIDANCE | GOBP_REGULATION_OF_AXON_GUIDANCE | GOBP_REGULATION_OF_AXON_GUIDANCE | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | POU4F2/TUBB2B/PTPRO/NOVA2 | 4 |
| GOBP_SHORT_TERM_MEMORY | GOBP_SHORT_TERM_MEMORY | GOBP_SHORT_TERM_MEMORY | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | CALB1/BRINP1/CUX2/CHRNA7 | 4 |
| GOCC_L_TYPE_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | GOCC_L_TYPE_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | GOCC_L_TYPE_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | CACNA1D/CACNG4/CACNG1/CACNG7 | 4 |
| GOMF_BENZODIAZEPINE_RECEPTOR_ACTIVITY | GOMF_BENZODIAZEPINE_RECEPTOR_ACTIVITY | GOMF_BENZODIAZEPINE_RECEPTOR_ACTIVITY | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | GABRG1/GABRG2/GABRA5/GABRG3 | 4 |
| GOMF_CALCIUM_CATION_ANTIPORTER_ACTIVITY | GOMF_CALCIUM_CATION_ANTIPORTER_ACTIVITY | GOMF_CALCIUM_CATION_ANTIPORTER_ACTIVITY | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | SLC8A1/SLC24A2/SLC8A3/SLC8A2 | 4 |
| HP_LOW_SELF_ESTEEM | HP_LOW_SELF_ESTEEM | HP_LOW_SELF_ESTEEM | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | IRF6/GABRG2/NECTIN1/GABRB3 | 4 |
| HP_PARASOMNIA | HP_PARASOMNIA | HP_PARASOMNIA | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | CHRNB2/TFAP2B/CHRNA2/MAGEL2 | 4 |
| REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING | REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING | REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING | 4/1243 | 11/23056 | 0.3636364 | 6.744972 | 4.549423 | 0.0020438 | 0.0307298 | 0.0270061 | CACNA2D2/CACNA1B/CACNG4/CACNG2 | 4 |
| GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | 17/1243 | 145/23056 | 0.1172414 | 2.174672 | 3.387186 | 0.0021224 | 0.0318173 | 0.0279619 | NGF/NTRK1/CHL1/ISL1/SNCB/TFAP2D/TFAP2B/GRIK2/EN2/NTRK2/STXBP1/FAIM2/GABRA5/BCL2/PRKCG/VSTM2L/PLA2G3 | 17 |
| GOBP_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 17/1243 | 145/23056 | 0.1172414 | 2.174672 | 3.387186 | 0.0021224 | 0.0318173 | 0.0279619 | PRKCZ/OPRD1/KANK4/ADD2/MAP2/VILL/CRACD/ISL1/DMTN/TMOD1/STXBP1/CARMIL2/LDLRAD4/TUBB4A/INPP5J/NLRP2B/TMSB4Y | 17 |
| GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | 10/1243 | 64/23056 | 0.1562500 | 2.898230 | 3.630036 | 0.0021239 | 0.0318173 | 0.0279619 | EPHA8/EPHA10/NTRK1/ALK/MST1R/EPHA6/PDGFRA/KIT/NTRK2/ROR2 | 10 |
| LE_NEURONAL_DIFFERENTIATION_UP | LE_NEURONAL_DIFFERENTIATION_UP | LE_NEURONAL_DIFFERENTIATION_UP | 5/1243 | 18/23056 | 0.2777778 | 5.152409 | 4.207019 | 0.0021460 | 0.0320294 | 0.0281483 | SYT11/ANK2/CNR1/CA10/SYT5 | 5 |
| LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES | LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES | LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES | 5/1243 | 18/23056 | 0.2777778 | 5.152409 | 4.207019 | 0.0021460 | 0.0320294 | 0.0281483 | HPCAL4/RGS8/PSD/KIF5A/SBK1 | 5 |
| STEIN_ESTROGEN_RESPONSE_NOT_VIA_ESRRA | STEIN_ESTROGEN_RESPONSE_NOT_VIA_ESRRA | STEIN_ESTROGEN_RESPONSE_NOT_VIA_ESRRA | 5/1243 | 18/23056 | 0.2777778 | 5.152409 | 4.207019 | 0.0021460 | 0.0320294 | 0.0281483 | SUSD4/GREB1/OLFM1/ABAT/TIAM1 | 5 |
| KEGG_CELL_ADHESION_MOLECULES_CAMS | KEGG_CELL_ADHESION_MOLECULES_CAMS | KEGG_CELL_ADHESION_MOLECULES_CAMS | 16/1243 | 133/23056 | 0.1203008 | 2.231419 | 3.399824 | 0.0021712 | 0.0322319 | 0.0283262 | CLDN19/CADM3/NFASC/CNTN2/NRXN1/CD8A/CD8B/CNTNAP2/NRXN2/NECTIN1/CNTN1/NRXN3/JAM2/ITGB2/NLGN3/L1CAM | 16 |
| BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_CELLS_UP | 12/1243 | 86/23056 | 0.1395349 | 2.588187 | 3.522336 | 0.0021747 | 0.0322319 | 0.0283262 | MAP2/ANK2/PCDH1/N4BP3/FYN/KCNQ3/SLC6A15/TM6SF1/ARRDC4/THEG/BEX2/RAB39B | 12 |
| GOBP_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 12/1243 | 86/23056 | 0.1395349 | 2.588187 | 3.522336 | 0.0021747 | 0.0322319 | 0.0283262 | PROX1/SOX11/SIX3/MEIS1/CRYGC/CRYGB/CRYBA2/BFSP2/TMOD1/CDKN1C/NECTIN1/CRYBB1 | 12 |
| REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | REACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | 12/1243 | 86/23056 | 0.1395349 | 2.588187 | 3.522336 | 0.0021747 | 0.0322319 | 0.0283262 | SLC44A5/SLC22A15/RHBG/SLC30A3/SLC6A11/SLC6A1/SLC18A1/SLC6A5/SLC22A6/SLC6A15/RHCG/SLC6A2 | 12 |
| HP_BREAST_HYPOPLASIA | HP_BREAST_HYPOPLASIA | HP_BREAST_HYPOPLASIA | 8/1243 | 44/23056 | 0.1818182 | 3.372486 | 3.760220 | 0.0021809 | 0.0322319 | 0.0283262 | IL17RD/PROK2/ESR1/FGF17/TAC3/DCC/PROKR2/ANOS1 | 8 |
| REACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS | REACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS | REACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS | 8/1243 | 44/23056 | 0.1818182 | 3.372486 | 3.760220 | 0.0021809 | 0.0322319 | 0.0283262 | LRRC7/TUBA3E/TUBB2A/TUBB2B/GRIN1/TUBA1A/TUBA3C/TUBB4A | 8 |
| GOBP_DIENCEPHALON_DEVELOPMENT | GOBP_DIENCEPHALON_DEVELOPMENT | GOBP_DIENCEPHALON_DEVELOPMENT | 11/1243 | 75/23056 | 0.1466667 | 2.720472 | 3.562495 | 0.0021920 | 0.0322319 | 0.0283262 | CHRNB2/SIX3/GATA2/SOX2/ISL1/POU3F2/CNTNAP2/KCNC1/DRD2/KCNC2/NR0B1 | 11 |
| FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN | FONTAINE_THYROID_TUMOR_UNCERTAIN_MALIGNANCY_DN | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | FRZB/HCLS1/ODAM/TWIST1/KLF1/KLK2 | 6 |
| GOBP_EMBRYONIC_CAMERA_TYPE_EYE_MORPHOGENESIS | GOBP_EMBRYONIC_CAMERA_TYPE_EYE_MORPHOGENESIS | GOBP_EMBRYONIC_CAMERA_TYPE_EYE_MORPHOGENESIS | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | PROX1/SOX11/SIX3/TWIST1/TH/BMP7 | 6 |
| GOBP_INNERVATION | GOBP_INNERVATION | GOBP_INNERVATION | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | NTRK1/ISL1/GABRA5/RNF165/PRKCG/SULF2 | 6 |
| GOBP_NEGATIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | ADORA1/ALK/GPLD1/CNR1/ADRA2A/PLIN5 | 6 |
| GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | ATP1B1/RYR2/SLC8A1/ANK2/CALM1/HRC | 6 |
| GOBP_SENSORY_PERCEPTION_OF_TEMPERATURE_STIMULUS | GOBP_SENSORY_PERCEPTION_OF_TEMPERATURE_STIMULUS | GOBP_SENSORY_PERCEPTION_OF_TEMPERATURE_STIMULUS | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | NTRK1/ADORA1/CXCR4/GRIK2/OPN4/ADRA2A | 6 |
| KONDO_COLON_CANCER_HCP_WITH_H3K27ME1 | KONDO_COLON_CANCER_HCP_WITH_H3K27ME1 | KONDO_COLON_CANCER_HCP_WITH_H3K27ME1 | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | CADM3/CXCR4/COL9A1/MRAP2/CCNA1/PCSK1N | 6 |
| REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | 6/1243 | 26/23056 | 0.2307692 | 4.280463 | 3.995170 | 0.0021997 | 0.0322319 | 0.0283262 | TUBA3E/TUBB2A/TUBB2B/TUBA1A/TUBA3C/TUBB4A | 6 |
| WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS | WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS | WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS | 18/1243 | 158/23056 | 0.1139241 | 2.113140 | 3.351506 | 0.0022020 | 0.0322319 | 0.0283262 | PRKCZ/PDE4B/RGS5/RGS16/GNG4/RYR2/RGS7/SLC8A1/IGFBP2/ADCY5/GUCY1A1/PKIB/RLN1/NOS1/CALM1/RGS11/GNG8/PRKCG | 18 |
| HP_SHORT_ATTENTION_SPAN | HP_SHORT_ATTENTION_SPAN | HP_SHORT_ATTENTION_SPAN | 41/1243 | 477/23056 | 0.0859539 | 1.594330 | 3.131087 | 0.0022730 | 0.0332309 | 0.0292041 | DNAJC6/NTNG1/CHRNB2/NTRK1/MYT1L/DPYSL5/SIX3/SCN3A/SCN1A/SLC6A1/SATB1/FGF12/GABRG2/TUBB2B/GRIK2/DLL1/ACTL6B/CHRNA2/NTRK2/STXBP1/CACNA1B/CELF2/DNAJC12/NODAL/CDKN1C/SLC1A2/GRIA4/PAH/SLITRK1/MAGEL2/GABRB3/GABRA5/CHRNA7/MCTP2/PRKCG/TSPAN7/SYP/NEXMIF/ZNF711/PAK3/RAB39B | 41 |
| HP_ABNORMALITY_OF_THE_SENSE_OF_SMELL | HP_ABNORMALITY_OF_THE_SENSE_OF_SMELL | HP_ABNORMALITY_OF_THE_SENSE_OF_SMELL | 13/1243 | 98/23056 | 0.1326531 | 2.460538 | 3.458751 | 0.0023039 | 0.0336421 | 0.0295655 | DNAJC6/SIX3/IL17RD/PROK2/SOX2/RELN/FGF17/ANK1/TAC3/ARNT2/DCC/PROKR2/ANOS1 | 13 |
| GOBP_RELAXATION_OF_MUSCLE | GOBP_RELAXATION_OF_MUSCLE | GOBP_RELAXATION_OF_MUSCLE | 7/1243 | 35/23056 | 0.2000000 | 3.709735 | 3.829650 | 0.0023153 | 0.0337685 | 0.0296766 | PDE4B/ATP1B1/ADORA1/SLC8A1/GUCY1A1/CHGA/HRC | 7 |
| GOBP_VESICLE_ORGANIZATION | GOBP_VESICLE_ORGANIZATION | GOBP_VESICLE_ORGANIZATION | 29/1243 | 306/23056 | 0.0947712 | 1.757881 | 3.185894 | 0.0023757 | 0.0345284 | 0.0303444 | VAV3/SYT11/DYSF/PTPRN/CPLX1/CPLX2/SNAP91/CCDC136/STXBP1/SYT13/SYT7/RAB39A/ACRBP/PMEL/P2RX7/STXBP6/CPLX3/STX1B/DOC2B/VAMP2/SYT4/BCL2/UNC13A/RAB3A/SNAP25/PLA2G3/PHETA2/SYP/ZDHHC15 | 29 |
| LEE_NEURAL_CREST_STEM_CELL_DN | LEE_NEURAL_CREST_STEM_CELL_DN | LEE_NEURAL_CREST_STEM_CELL_DN | 15/1243 | 122/23056 | 0.1229508 | 2.280575 | 3.385363 | 0.0023760 | 0.0345284 | 0.0303444 | SIX3/PROM1/NPY2R/FUT9/CNTNAP2/FGF17/MPPED2/SLITRK5/BEGAIN/DLK1/BCL2/BMP7/CHRDL1/CAPN6/TKTL1 | 15 |
| WP_FRAGILE_X_SYNDROME | WP_FRAGILE_X_SYNDROME | WP_FRAGILE_X_SYNDROME | 15/1243 | 122/23056 | 0.1229508 | 2.280575 | 3.385363 | 0.0023760 | 0.0345284 | 0.0303444 | GABRD/RAP1GAP/DLGAP3/SLC6A1/GRIP2/GABRG2/CNR1/FYN/NTRK2/GRIN1/KCNC1/PTPN5/GRM5/ABAT/SHANK1 | 15 |
| GOBP_MECHANORECEPTOR_DIFFERENTIATION | GOBP_MECHANORECEPTOR_DIFFERENTIATION | GOBP_MECHANORECEPTOR_DIFFERENTIATION | 10/1243 | 65/23056 | 0.1538462 | 2.853642 | 3.572432 | 0.0023912 | 0.0346668 | 0.0304661 | NTRK1/ADGRV1/LHFPL5/DLL1/NTRK2/CDH23/USH1C/GABRA5/STRC/TMEM132E | 10 |
| GOBP_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | 10/1243 | 65/23056 | 0.1538462 | 2.853642 | 3.572432 | 0.0023912 | 0.0346668 | 0.0304661 | ADORA1/CHRM3/PROK2/KIT/GUCY1A1/KCNB2/ADRA2A/CHRNA3/CHRNB4/ABAT | 10 |
| GOBP_PEPTIDYL_TYROSINE_MODIFICATION | GOBP_PEPTIDYL_TYROSINE_MODIFICATION | GOBP_PEPTIDYL_TYROSINE_MODIFICATION | 34/1243 | 377/23056 | 0.0901857 | 1.672825 | 3.144278 | 0.0024170 | 0.0349857 | 0.0307463 | PRKCZ/EPHA8/EPHA10/NTRK1/ADORA1/ALK/MST1R/EPHA6/HCLS1/PDGFRA/KIT/SFRP2/ISL1/TTBK1/CD24/FYN/RELN/DMTN/ENPP2/NTRK2/SYK/ROR2/NEURL1/ADRA2A/AFAP1L2/GFRA1/GRM5/CNTN1/SRCIN1/ACE/AATK/SRMS/SAMSN1/ITGB2 | 34 |
| REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 21/1243 | 198/23056 | 0.1060606 | 1.967283 | 3.263080 | 0.0024205 | 0.0349857 | 0.0307463 | OPRD1/HCRTR1/ACKR1/PROKR1/CXCR4/PROK2/AGTR1/ECE2/KNG1/NPY2R/OPRM1/NPY/RLN2/PRLHR/GAL/TAC3/PPY/SSTR2/MC4R/PROKR2/EDN3 | 21 |
| GOMF_DNA_BINDING_TRANSCRIPTION_ACTIVATOR_ACTIVITY | GOMF_DNA_BINDING_TRANSCRIPTION_ACTIVATOR_ACTIVITY | GOMF_DNA_BINDING_TRANSCRIPTION_ACTIVATOR_ACTIVITY | 40/1243 | 464/23056 | 0.0862069 | 1.599023 | 3.111616 | 0.0024226 | 0.0349857 | 0.0307463 | IRF6/ESRRG/SOX11/SIX3/MEIS1/CSRNP3/HOXD8/HOXD3/KLF7/FEV/KLF15/GATA2/SOX2/POU4F2/HAND2/DUX4/ISL1/HAND1/SOX4/TFAP2B/POU3F2/RFX6/MYB/ESR1/NKX6-3/PAX5/SPI1/HOXC10/HOXC4/ONECUT1/ARNT2/IRX6/HLF/TCF4/ONECUT2/ZNF208/ZNF99/ZNF229/MAFB/CTCFL | 40 |
| WP_RAS_SIGNALING | WP_RAS_SIGNALING | WP_RAS_SIGNALING | 20/1243 | 185/23056 | 0.1081081 | 2.005262 | 3.277049 | 0.0024247 | 0.0349857 | 0.0307463 | PIK3R3/NTRK1/GNG4/PDGFRA/KIT/TTBK1/RAPGEF5/NTRK2/GRIN1/RASAL1/KSR2/PLA2G1B/CALM1/RASAL3/GNG8/PRKCG/PAK5/TIAM1/PLA2G3/PAK3 | 20 |
| GOBP_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 9/1243 | 55/23056 | 0.1636364 | 3.035237 | 3.607310 | 0.0025242 | 0.0362353 | 0.0318445 | GATA2/KIT/CPLX2/SYK/STXBP1/CHGA/VAMP2/PLA2G3/IL13RA2 | 9 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 9/1243 | 55/23056 | 0.1636364 | 3.035237 | 3.607310 | 0.0025242 | 0.0362353 | 0.0318445 | ADORA1/CD24/RELN/NEURL1/ADRA2A/AFAP1L2/GRM5/SRCIN1/ACE | 9 |
| REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | 9/1243 | 55/23056 | 0.1636364 | 3.035237 | 3.607310 | 0.0025242 | 0.0362353 | 0.0318445 | ATP1B1/ATP2B2/ATP13A4/ATP8A1/ATP8A2/CALM1/ATP4A/ATP1A3/ATP2B3 | 9 |
| GOBP_POSITIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT | 8/1243 | 45/23056 | 0.1777778 | 3.297542 | 3.682666 | 0.0025292 | 0.0362353 | 0.0318445 | SLC6A1/SLC38A3/ACSL1/STXBP1/P2RX7/ABAT/SYT4/PLA2G3 | 8 |
| GOMF_ISOPRENOID_BINDING | GOMF_ISOPRENOID_BINDING | GOMF_ISOPRENOID_BINDING | 8/1243 | 45/23056 | 0.1777778 | 3.297542 | 3.682666 | 0.0025292 | 0.0362353 | 0.0318445 | RBP7/ABCA4/RBP1/ADH4/LCN12/OPN4/SERPINA5/CRABP1 | 8 |
| SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN | 8/1243 | 45/23056 | 0.1777778 | 3.297542 | 3.682666 | 0.0025292 | 0.0362353 | 0.0318445 | ELAVL4/MEIS1/SOX4/OLFM1/SLITRK1/SYT4/TCF4/TIAM1 | 8 |
| AFFAR_YY1_TARGETS_UP | AFFAR_YY1_TARGETS_UP | AFFAR_YY1_TARGETS_UP | 21/1243 | 199/23056 | 0.1055276 | 1.957398 | 3.237947 | 0.0025723 | 0.0368086 | 0.0323483 | SYT11/PROX1/SOX2/SPOCK3/CTNND2/SELENOP/ELOVL2/GADD45G/NRG3/CDKN1C/MAP6/FXYD6-FXYD2/ABAT/CBLN1/CELF4/SLC1A6/SULF2/CHODL/NAP1L3/BEX2/GRIA3 | 21 |
| GOBP_INORGANIC_ION_IMPORT_ACROSS_PLASMA_MEMBRANE | GOBP_INORGANIC_ION_IMPORT_ACROSS_PLASMA_MEMBRANE | GOBP_INORGANIC_ION_IMPORT_ACROSS_PLASMA_MEMBRANE | 14/1243 | 111/23056 | 0.1261261 | 2.339472 | 3.376849 | 0.0025767 | 0.0368283 | 0.0323657 | KCNJ9/ATP1B1/SLC8A1/SLC6A1/FYN/KCNK9/SLC24A2/KCNJ11/KCNJ8/SLC8A3/ATP4A/ATP1A3/SLC8A2/KCNJ6 | 14 |
| MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | 12/1243 | 88/23056 | 0.1363636 | 2.529364 | 3.431240 | 0.0026473 | 0.0377930 | 0.0332134 | NPPA/TUBB2B/AZGP1/DMTN/CDKN1C/HRK/HS3ST2/C1QL1/POU2F2/PPFIA3/NPEPL1/MAPK8IP2 | 12 |
| WP_PRADERWILLI_AND_ANGELMAN_SYNDROME | WP_PRADERWILLI_AND_ANGELMAN_SYNDROME | WP_PRADERWILLI_AND_ANGELMAN_SYNDROME | 10/1243 | 66/23056 | 0.1515152 | 2.810405 | 3.515917 | 0.0026848 | 0.0382834 | 0.0336444 | GABRD/PRKCZ/NGF/GABRG1/GABRG2/GABRR2/MAGEL2/GABRB3/GABRA5/GABRG3 | 10 |
| GOBP_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING_INVOLVED_IN_CARDIAC_CONDUCTION | GOBP_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING_INVOLVED_IN_CARDIAC_CONDUCTION | GOBP_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING_INVOLVED_IN_CARDIAC_CONDUCTION | 6/1243 | 27/23056 | 0.2222222 | 4.121927 | 3.874606 | 0.0027008 | 0.0382876 | 0.0336481 | ATP1B1/RYR2/SLC8A1/CALM1/ATP1A3/HRC | 6 |
| GOBP_POSITIVE_REGULATION_OF_HEART_RATE | GOBP_POSITIVE_REGULATION_OF_HEART_RATE | GOBP_POSITIVE_REGULATION_OF_HEART_RATE | 6/1243 | 27/23056 | 0.2222222 | 4.121927 | 3.874606 | 0.0027008 | 0.0382876 | 0.0336481 | NPPA/RYR2/SCN3B/GCH1/HRC/EDN3 | 6 |
| GOBP_THYROID_HORMONE_METABOLIC_PROCESS | GOBP_THYROID_HORMONE_METABOLIC_PROCESS | GOBP_THYROID_HORMONE_METABOLIC_PROCESS | 6/1243 | 27/23056 | 0.2222222 | 4.121927 | 3.874606 | 0.0027008 | 0.0382876 | 0.0336481 | TPO/SLC16A10/CPQ/DIO3/DUOXA1/DUOX1 | 6 |
| GOMF_ATPASE_COUPLED_INTRAMEMBRANE_LIPID_TRANSPORTER_ACTIVITY | GOMF_ATPASE_COUPLED_INTRAMEMBRANE_LIPID_TRANSPORTER_ACTIVITY | GOMF_ATPASE_COUPLED_INTRAMEMBRANE_LIPID_TRANSPORTER_ACTIVITY | 6/1243 | 27/23056 | 0.2222222 | 4.121927 | 3.874606 | 0.0027008 | 0.0382876 | 0.0336481 | ABCA4/ABCA12/ATP8A1/ABCB4/ATP8A2/ABCG1 | 6 |
| HP_HEPATOBLASTOMA | HP_HEPATOBLASTOMA | HP_HEPATOBLASTOMA | 6/1243 | 27/23056 | 0.2222222 | 4.121927 | 3.874606 | 0.0027008 | 0.0382876 | 0.0336481 | SOX11/SOX4/PKHD1/CDKN1C/DLK1/RTL1 | 6 |
| MIKKELSEN_MCV6_ICP_WITH_H3K27ME3 | MIKKELSEN_MCV6_ICP_WITH_H3K27ME3 | MIKKELSEN_MCV6_ICP_WITH_H3K27ME3 | 11/1243 | 77/23056 | 0.1428571 | 2.649810 | 3.461579 | 0.0027117 | 0.0383964 | 0.0337437 | LINGO4/TFAP2B/PAX5/TH/SHANK2/CUX2/KCNK10/ISLR2/CHRNB4/NCAN/POU2F2 | 11 |
| BHAT_ESR1_TARGETS_VIA_AKT1_UP | BHAT_ESR1_TARGETS_VIA_AKT1_UP | BHAT_ESR1_TARGETS_VIA_AKT1_UP | 27/1243 | 281/23056 | 0.0960854 | 1.782257 | 3.149443 | 0.0027173 | 0.0384319 | 0.0337749 | MANEAL/BRINP2/RGS16/GREB1/HK2/GPRIN1/UNC5A/TUBB2B/PKIB/MYB/GADD45G/TH/LMO1/MPPED2/TUBA3C/DHRS2/CALM1/DEGS2/BEGAIN/GSG1L/MAPT/CHST8/SYNDIG1/CCM2L/KCNK15/RIMS4/TIAM1 | 27 |
| HALLMARK_KRAS_SIGNALING_UP | HALLMARK_KRAS_SIGNALING_UP | HALLMARK_KRAS_SIGNALING_UP | 21/1243 | 200/23056 | 0.1050000 | 1.947611 | 3.212959 | 0.0027320 | 0.0385637 | 0.0338908 | NGF/RGS16/CXCR4/KIF5C/SATB1/PRKG2/GUCY1A1/SNAP91/MAP7/RELN/GADD45G/USH1C/IL10RA/SCG3/ACE/MAP4K1/SNAP25/MAFB/ITGB2/TSPAN7/PCSK1N | 21 |
| GOBP_POSTSYNAPTIC_MEMBRANE_ORGANIZATION | GOBP_POSTSYNAPTIC_MEMBRANE_ORGANIZATION | GOBP_POSTSYNAPTIC_MEMBRANE_ORGANIZATION | 7/1243 | 36/23056 | 0.1944444 | 3.606686 | 3.736352 | 0.0027425 | 0.0385637 | 0.0338908 | NRXN1/LHFPL4/RELN/NRXN2/SHISA7/NLGN3/NLGN4Y | 7 |
| GOCC_DENDRITIC_SHAFT | GOCC_DENDRITIC_SHAFT | GOCC_DENDRITIC_SHAFT | 7/1243 | 36/23056 | 0.1944444 | 3.606686 | 3.736352 | 0.0027425 | 0.0385637 | 0.0338908 | SLC8A1/MAP2/CNIH2/GRM5/JPH4/SYNDIG1/INPP5J | 7 |
| GOMF_NEUROPEPTIDE_RECEPTOR_BINDING | GOMF_NEUROPEPTIDE_RECEPTOR_BINDING | GOMF_NEUROPEPTIDE_RECEPTOR_BINDING | 7/1243 | 36/23056 | 0.1944444 | 3.606686 | 3.736352 | 0.0027425 | 0.0385637 | 0.0338908 | NPPA/MRAP2/NPY/GAL/PPY/SHANK1/EDN3 | 7 |
| HP_DYSPAREUNIA | HP_DYSPAREUNIA | HP_DYSPAREUNIA | 7/1243 | 36/23056 | 0.1944444 | 3.606686 | 3.736352 | 0.0027425 | 0.0385637 | 0.0338908 | IL17RD/PROK2/FGF17/CDH23/DCC/PROKR2/ANOS1 | 7 |
| GOBP_DETECTION_OF_TEMPERATURE_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION | GOBP_DETECTION_OF_TEMPERATURE_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION | GOBP_DETECTION_OF_TEMPERATURE_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | NTRK1/ADORA1/CXCR4/GRIK2/OPN4 | 5 |
| GOBP_PHOTOTRANSDUCTION_VISIBLE_LIGHT | GOBP_PHOTOTRANSDUCTION_VISIBLE_LIGHT | GOBP_PHOTOTRANSDUCTION_VISIBLE_LIGHT | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | ABCA4/PDE6B/GRK1/GUCY2D/RS1 | 5 |
| GOCC_ASTROCYTE_PROJECTION | GOCC_ASTROCYTE_PROJECTION | GOCC_ASTROCYTE_PROJECTION | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | GRM2/SLC1A2/GRM5/SLC17A8/SYT4 | 5 |
| GOMF_NARROW_PORE_CHANNEL_ACTIVITY | GOMF_NARROW_PORE_CHANNEL_ACTIVITY | GOMF_NARROW_PORE_CHANNEL_ACTIVITY | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | KCNK3/KCNK9/KCNK7/KCNK10/KCNK15 | 5 |
| GOMF_NEUROTRANSMITTER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_NEUROTRANSMITTER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_NEUROTRANSMITTER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | CPLX1/SLC6A15/SLC17A8/CPLX3/SLC6A2 | 5 |
| GOMF_P_TYPE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_P_TYPE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_P_TYPE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | ATP1B1/ATP2B2/ATP4A/ATP1A3/ATP2B3 | 5 |
| GOMF_STRUCTURAL_CONSTITUENT_OF_SYNAPSE | GOMF_STRUCTURAL_CONSTITUENT_OF_SYNAPSE | GOMF_STRUCTURAL_CONSTITUENT_OF_SYNAPSE | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | BSN/ERC2/INA/SHANK2/NEFH | 5 |
| HP_STEREOTYPICAL_HAND_WRINGING | HP_STEREOTYPICAL_HAND_WRINGING | HP_STEREOTYPICAL_HAND_WRINGING | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | NTNG1/SATB1/STXBP1/VAMP2/NEXMIF | 5 |
| REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL | REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL | REACTOME_PHASE_4_RESTING_MEMBRANE_POTENTIAL | 5/1243 | 19/23056 | 0.2631579 | 4.881230 | 4.040114 | 0.0027844 | 0.0387493 | 0.0340539 | KCNK3/KCNK9/KCNK7/KCNK10/KCNK15 | 5 |
| GOBP_RECEPTOR_CLUSTERING | GOBP_RECEPTOR_CLUSTERING | GOBP_RECEPTOR_CLUSTERING | 9/1243 | 56/23056 | 0.1607143 | 2.981037 | 3.543097 | 0.0028665 | 0.0398452 | 0.0350170 | LRRC7/NRXN1/LHFPL4/SLITRK3/GRIK2/RELN/NRXN2/SHISA7/ITGB2 | 9 |
| GOBP_VENTRAL_SPINAL_CORD_DEVELOPMENT | GOBP_VENTRAL_SPINAL_CORD_DEVELOPMENT | GOBP_VENTRAL_SPINAL_CORD_DEVELOPMENT | 8/1243 | 46/23056 | 0.1739130 | 3.225856 | 3.607266 | 0.0029196 | 0.0402531 | 0.0353754 | GATA2/ISL1/SOX4/RELN/VSTM5/HOXC10/ASCL1/FOXN4 | 8 |
| GOBP_LIPID_LOCALIZATION | GOBP_LIPID_LOCALIZATION | GOBP_LIPID_LOCALIZATION | 40/1243 | 469/23056 | 0.0852878 | 1.581976 | 3.039645 | 0.0029260 | 0.0402531 | 0.0353754 | RBP7/DISP3/ABCA4/PLPPR4/APOB/OSBPL6/ABCA12/RBP1/PLSCR5/AGTR1/ATP8A1/SLC10A4/ACSL1/FABP6/VSTM2A/ABCB4/XKR5/SYK/SYT7/SLC22A24/GAL/FGF19/DRD2/SLCO1B1/ABCD2/PLA2G1B/P2RX7/ATP8A2/IRS2/FITM1/SERPINA5/SLC27A2/CRABP1/SMIM22/SLC4A1/ACE/PLIN5/XKR7/ABCG1/PLA2G3 | 40 |
| GOBP_MESODERMAL_CELL_FATE_SPECIFICATION | GOBP_MESODERMAL_CELL_FATE_SPECIFICATION | GOBP_MESODERMAL_CELL_FATE_SPECIFICATION | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | SFRP2/EYA1/NODAL/EYA2 | 4 |
| GOBP_SECRETORY_GRANULE_LOCALIZATION | GOBP_SECRETORY_GRANULE_LOCALIZATION | GOBP_SECRETORY_GRANULE_LOCALIZATION | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | MAP2/KIF1A/KIF5A/SYT4 | 4 |
| GOBP_SUBSTRATE_INDEPENDENT_TELENCEPHALIC_TANGENTIAL_MIGRATION | GOBP_SUBSTRATE_INDEPENDENT_TELENCEPHALIC_TANGENTIAL_MIGRATION | GOBP_SUBSTRATE_INDEPENDENT_TELENCEPHALIC_TANGENTIAL_MIGRATION | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | CNTN2/NRG3/SLIT1/DRD2 | 4 |
| GOCC_ANCHORED_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_SYNAPTIC_VESICLE_MEMBRANE | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | RAB3C/CPLX3/RAB3A/SYN1 | 4 |
| GOCC_CLATHRIN_SCULPTED_VESICLE | GOCC_CLATHRIN_SCULPTED_VESICLE | GOCC_CLATHRIN_SCULPTED_VESICLE | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | SLC18A1/VAMP2/RAB3A/SLC32A1 | 4 |
| GOMF_ADENYLATE_CYCLASE_BINDING | GOMF_ADENYLATE_CYCLASE_BINDING | GOMF_ADENYLATE_CYCLASE_BINDING | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | ADCY5/ADCYAP1R1/AKAP6/CALM1 | 4 |
| HP_ANGIOEDEMA | HP_ANGIOEDEMA | HP_ANGIOEDEMA | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | KNG1/SPINK5/F12/XPNPEP2 | 4 |
| HP_FOCAL_MOTOR_STATUS_EPILEPTICUS | HP_FOCAL_MOTOR_STATUS_EPILEPTICUS | HP_FOCAL_MOTOR_STATUS_EPILEPTICUS | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | SCN1A/GABRG2/STXBP1/PDE2A | 4 |
| REACTOME_ALK_MUTANTS_BIND_TKIS | REACTOME_ALK_MUTANTS_BIND_TKIS | REACTOME_ALK_MUTANTS_BIND_TKIS | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | ALK/EML4/PPM1B/BCL11A | 4 |
| REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | 4/1243 | 12/23056 | 0.3333333 | 6.182891 | 4.286908 | 0.0029356 | 0.0402531 | 0.0353754 | KCNK3/KCNK9/KCNK7/KCNK10 | 4 |
| GOCC_SARCOPLASM | GOCC_SARCOPLASM | GOCC_SARCOPLASM | 11/1243 | 78/23056 | 0.1410256 | 2.615838 | 3.412318 | 0.0030064 | 0.0409942 | 0.0360267 | RYR2/HK2/ANK1/NOS1/JPH4/AKAP6/SLC8A3/JPH3/JSRP1/RTN2/HRC | 11 |
| HP_ORAL_PHARYNGEAL_DYSPHAGIA | HP_ORAL_PHARYNGEAL_DYSPHAGIA | HP_ORAL_PHARYNGEAL_DYSPHAGIA | 11/1243 | 78/23056 | 0.1410256 | 2.615838 | 3.412318 | 0.0030064 | 0.0409942 | 0.0360267 | IRF6/MYT1L/KIF1A/DLL1/STXBP1/GRIN1/BRSK2/NECTIN1/TCF4/ATP1A3/CACNG2 | 11 |
| GOBP_POSITIVE_REGULATION_OF_INSULIN_SECRETION | GOBP_POSITIVE_REGULATION_OF_INSULIN_SECRETION | GOBP_POSITIVE_REGULATION_OF_INSULIN_SECRETION | 10/1243 | 67/23056 | 0.1492537 | 2.768459 | 3.460451 | 0.0030065 | 0.0409942 | 0.0360267 | VSNL1/MYRIP/GPR27/ISL1/SOX4/GPLD1/RFX6/IRS2/ABAT/DOC2B | 10 |
| GOCC_NEUROMUSCULAR_JUNCTION | GOCC_NEUROMUSCULAR_JUNCTION | GOCC_NEUROMUSCULAR_JUNCTION | 10/1243 | 67/23056 | 0.1492537 | 2.768459 | 3.460451 | 0.0030065 | 0.0409942 | 0.0360267 | DLGAP3/CHRNA1/CHRND/TUBA1A/P2RX7/SLC8A3/STX1B/CDK5R1/UNC13A/SYP | 10 |
| GOMF_SCAFFOLD_PROTEIN_BINDING | GOMF_SCAFFOLD_PROTEIN_BINDING | GOMF_SCAFFOLD_PROTEIN_BINDING | 10/1243 | 67/23056 | 0.1492537 | 2.768459 | 3.460451 | 0.0030065 | 0.0409942 | 0.0360267 | SCN5A/GRM2/ADCY5/FYN/DLL1/SYK/NOS1/SHANK1/NLGN3/NLGN4Y | 10 |
| GOMF_SH3_DOMAIN_BINDING | GOMF_SH3_DOMAIN_BINDING | GOMF_SH3_DOMAIN_BINDING | 15/1243 | 125/23056 | 0.1200000 | 2.225841 | 3.280484 | 0.0030122 | 0.0410263 | 0.0360549 | DNAJC6/SGIP1/HCLS1/AFAP1L1/KHDRBS2/SH3BGRL2/ELMO1/AFAP1L2/SHANK2/DTX1/EFS/MAPT/SHANK1/INPP5J/PAK3 | 15 |
| REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | 14/1243 | 113/23056 | 0.1238938 | 2.298066 | 3.301955 | 0.0030436 | 0.0414068 | 0.0363893 | PIK3R3/THEM4/PDGFRA/KIT/NRG2/FYN/ESR1/FGF17/NRG3/PIK3AP1/FGF19/FGF6/KL/IRS2 | 14 |
| REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | 22/1243 | 216/23056 | 0.1018519 | 1.889217 | 3.134345 | 0.0031994 | 0.0434400 | 0.0381762 | HCRTR1/PIK3R3/RGS5/RGS16/RGS13/GNG4/CHRM3/PROKR1/PROK2/AGTR1/KNG1/GPRC6A/DGKB/OPN4/CHRM1/GRM5/TAC3/P2RY11/GNG8/PROKR2/EDN3/DGKK | 22 |
| GOBP_REGULATION_OF_SODIUM_ION_TRANSPORT | GOBP_REGULATION_OF_SODIUM_ION_TRANSPORT | GOBP_REGULATION_OF_SODIUM_ION_TRANSPORT | 12/1243 | 90/23056 | 0.1333333 | 2.473156 | 3.342626 | 0.0032002 | 0.0434400 | 0.0381762 | ATP1B1/SLC8A1/SCN5A/FGF12/DRD2/SCN4B/SCN3B/CNTN1/NOS1/P2RX7/FGF14/FGF11 | 12 |
| GOBP_REGULATION_OF_ACTION_POTENTIAL | GOBP_REGULATION_OF_ACTION_POTENTIAL | GOBP_REGULATION_OF_ACTION_POTENTIAL | 9/1243 | 57/23056 | 0.1578947 | 2.928738 | 3.480299 | 0.0032443 | 0.0439905 | 0.0386599 | CHRNB2/RYR2/SCN5A/FGF12/ANK2/CNR1/CALM1/DSC2/SLC8A2 | 9 |
| CHEBOTAEV_GR_TARGETS_DN | CHEBOTAEV_GR_TARGETS_DN | CHEBOTAEV_GR_TARGETS_DN | 15/1243 | 126/23056 | 0.1190476 | 2.208175 | 3.246188 | 0.0032531 | 0.0440604 | 0.0387214 | DNAJC6/VAV3/BCL2L15/ATP8A1/JAZF1/CA8/ZNF704/ELAVL2/SORCS3/CNTN1/PDZRN4/NRXN3/SMIM22/RTN2/GPM6B | 15 |
| BIOCARTA_NO1_PATHWAY | BIOCARTA_NO1_PATHWAY | BIOCARTA_NO1_PATHWAY | 6/1243 | 28/23056 | 0.2142857 | 3.974715 | 3.759731 | 0.0032828 | 0.0442654 | 0.0389016 | RYR2/CHRNA1/KNG1/CHRM1/PDE2A/CALM1 | 6 |
| HP_CONE_CONE_ROD_DYSTROPHY | HP_CONE_CONE_ROD_DYSTROPHY | HP_CONE_CONE_ROD_DYSTROPHY | 6/1243 | 28/23056 | 0.2142857 | 3.974715 | 3.759731 | 0.0032828 | 0.0442654 | 0.0389016 | ABCA4/PROM1/GUCA1A/RIMS1/GUCY2D/CACNA1F | 6 |
| LEE_DOUBLE_POLAR_THYMOCYTE | LEE_DOUBLE_POLAR_THYMOCYTE | LEE_DOUBLE_POLAR_THYMOCYTE | 6/1243 | 28/23056 | 0.2142857 | 3.974715 | 3.759731 | 0.0032828 | 0.0442654 | 0.0389016 | CD8A/CD8B/CPLX1/HRK/ACSBG1/SLC7A3 | 6 |
| REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION | REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION | REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION | 6/1243 | 28/23056 | 0.2142857 | 3.974715 | 3.759731 | 0.0032828 | 0.0442654 | 0.0389016 | GNG4/CACNA2D2/CACNA1D/ADCY5/ADRA2A/GNG8 | 6 |
| WP_NEURAL_CREST_DIFFERENTIATION | WP_NEURAL_CREST_DIFFERENTIATION | WP_NEURAL_CREST_DIFFERENTIATION | 13/1243 | 102/23056 | 0.1274510 | 2.364047 | 3.295797 | 0.0032908 | 0.0443235 | 0.0389526 | PAX7/ISL1/HAND1/TFAP2B/MYB/DLL1/TWIST1/FGF19/ASCL1/TCF4/CDH7/DLL3/BMP7 | 13 |
| CHANDRAN_METASTASIS_DN | CHANDRAN_METASTASIS_DN | CHANDRAN_METASTASIS_DN | 29/1243 | 313/23056 | 0.0926518 | 1.718567 | 3.055456 | 0.0032992 | 0.0443727 | 0.0389958 | PDE4B/TSPAN2/CHRM3/SCN7A/IGFBP2/CNTN3/PPM1L/B3GALNT1/SOX2/PARM1/RNF150/SPOCK3/ISL1/PSD2/AZGP1/PTPRN2/PI15/RLN1/SORBS1/TRIM29/PDZRN4/SLC22A17/EFS/MCTP2/APCDD1/WFDC2/BMP7/NEFH/SERTM2 | 29 |
| GOBP_RENAL_SYSTEM_PROCESS | GOBP_RENAL_SYSTEM_PROCESS | GOBP_RENAL_SYSTEM_PROCESS | 14/1243 | 114/23056 | 0.1228070 | 2.277907 | 3.265100 | 0.0033017 | 0.0443727 | 0.0389958 | CHRNB2/ADORA1/AGTR1/TFAP2B/SLC22A6/DRD2/PTPRO/TMEM63C/CHRNA3/CHRNB4/SLC4A1/ACE/BCL2/SULF2 | 14 |
| DOANE_BREAST_CANCER_ESR1_DN | DOANE_BREAST_CANCER_ESR1_DN | DOANE_BREAST_CANCER_ESR1_DN | 8/1243 | 47/23056 | 0.1702128 | 3.157221 | 3.533907 | 0.0033553 | 0.0448335 | 0.0394008 | PGBD5/SOX11/BCL11A/ROPN1/UGT8/GABRP/GAL/DSC2 | 8 |
| FIGUEROA_AML_METHYLATION_CLUSTER_5_DN | FIGUEROA_AML_METHYLATION_CLUSTER_5_DN | FIGUEROA_AML_METHYLATION_CLUSTER_5_DN | 8/1243 | 47/23056 | 0.1702128 | 3.157221 | 3.533907 | 0.0033553 | 0.0448335 | 0.0394008 | CHRNA1/C10orf82/SYT13/CD3G/FAM90A1/ASXL3/TIAM1/ITGB2 | 8 |
| GOBP_ACID_SECRETION | GOBP_ACID_SECRETION | GOBP_ACID_SECRETION | 8/1243 | 47/23056 | 0.1702128 | 3.157221 | 3.533907 | 0.0033553 | 0.0448335 | 0.0394008 | PTGER3/AGXT/SLC6A1/HRH2/ABCB4/DRD2/P2RX7/ABAT | 8 |
| GOBP_RESPONSE_TO_NERVE_GROWTH_FACTOR | GOBP_RESPONSE_TO_NERVE_GROWTH_FACTOR | GOBP_RESPONSE_TO_NERVE_GROWTH_FACTOR | 8/1243 | 47/23056 | 0.1702128 | 3.157221 | 3.533907 | 0.0033553 | 0.0448335 | 0.0394008 | ELAVL4/NGF/NTRK1/TMEM108/NTRK2/KCNC1/KCNC2/MAPT | 8 |
| KEGG_TYPE_II_DIABETES_MELLITUS | KEGG_TYPE_II_DIABETES_MELLITUS | KEGG_TYPE_II_DIABETES_MELLITUS | 8/1243 | 47/23056 | 0.1702128 | 3.157221 | 3.533907 | 0.0033553 | 0.0448335 | 0.0394008 | PRKCZ/PIK3R3/HK2/CACNA1D/HK3/CACNA1B/KCNJ11/IRS2 | 8 |
| HP_ERECTILE_DYSFUNCTION | HP_ERECTILE_DYSFUNCTION | HP_ERECTILE_DYSFUNCTION | 10/1243 | 68/23056 | 0.1470588 | 2.727746 | 3.405996 | 0.0033582 | 0.0448335 | 0.0394008 | IL17RD/PROK2/GUCY1A1/TFR2/FGF17/CDH23/TAC3/DCC/PROKR2/ANOS1 | 10 |
| HP_ABNORMAL_CIRCULATING_HORMONE_CONCENTRATION | HP_ABNORMAL_CIRCULATING_HORMONE_CONCENTRATION | HP_ABNORMAL_CIRCULATING_HORMONE_CONCENTRATION | 39/1243 | 458/23056 | 0.0851528 | 1.579472 | 2.990134 | 0.0033646 | 0.0448693 | 0.0394323 | CLDN19/ABCA4/TPO/PCARE/SIX3/IL17RD/PROK2/ARL6/PDE6B/PROM1/ESR1/DLL1/RP1L1/FGF17/DBH/NODAL/SLC29A3/CDH23/CDHR1/CDKN1C/KCNJ11/TAC3/KL/TDRD9/MAGEL2/ARNT2/MCTP2/IGFALS/CNGB1/TEX14/PRCD/DCC/MC4R/AMH/PROKR2/ANOS1/NR0B1/SHROOM4/NLGN3 | 39 |
| WP_GPCRS_CLASS_A_RHODOPSINLIKE | WP_GPCRS_CLASS_A_RHODOPSINLIKE | WP_GPCRS_CLASS_A_RHODOPSINLIKE | 25/1243 | 258/23056 | 0.0968992 | 1.797352 | 3.074482 | 0.0034203 | 0.0455625 | 0.0400415 | HTR6/OPRD1/HCRTR1/PTGER3/ADORA1/CHRM3/CXCR4/GPR27/AGTR1/NPY2R/HRH2/HTR1E/CNR1/OPRM1/GPR85/OPN4/ADRA2A/PRLHR/CHRM1/DRD2/GPR12/SSTR2/MC4R/P2RY11/HRH3 | 25 |
| GOCC_EXTRINSIC_COMPONENT_OF_MEMBRANE | GOCC_EXTRINSIC_COMPONENT_OF_MEMBRANE | GOCC_EXTRINSIC_COMPONENT_OF_MEMBRANE | 29/1243 | 314/23056 | 0.0923567 | 1.713094 | 3.037090 | 0.0034532 | 0.0459511 | 0.0403830 | HPCA/PIK3R3/RGS8/GNG4/CTNNA2/KIF1A/GFRA3/KCNIP1/ARMC12/SNAP91/FYN/DEFB1/SYK/CDH23/PSD/GFRA1/RPH3A/CARMIL2/RNF112/HID1/CDH7/GNG8/SNAP25/CDH22/SRMS/TIAM1/INPP5J/RS1/SYN1 | 29 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | 19/1243 | 178/23056 | 0.1067416 | 1.979915 | 3.132922 | 0.0035360 | 0.0467730 | 0.0411053 | CMPK2/RSAD2/MEIS1/CPA3/KIT/SOX4/PKIB/ABCB4/TFR2/DEFB1/DUSP4/PRSS3/ABCD2/CCNA1/TDRD9/APCDD1/MAP4K1/LAMP5/PPP1R16B | 19 |
| GOBP_ARF_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_ARF_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_ARF_PROTEIN_SIGNAL_TRANSDUCTION | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | FBXO8/PSD2/ARFGEF3/PSD/IQSEC3 | 5 |
| GOBP_POSTSYNAPTIC_SPECIALIZATION_ASSEMBLY | GOBP_POSTSYNAPTIC_SPECIALIZATION_ASSEMBLY | GOBP_POSTSYNAPTIC_SPECIALIZATION_ASSEMBLY | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | NRXN1/GAP43/SLITRK3/NRXN2/CBLN1 | 5 |
| GOBP_REGULATION_OF_CATECHOLAMINE_METABOLIC_PROCESS | GOBP_REGULATION_OF_CATECHOLAMINE_METABOLIC_PROCESS | GOBP_REGULATION_OF_CATECHOLAMINE_METABOLIC_PROCESS | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | CHRNB2/NPY/ABAT/ITGB2/MAOB | 5 |
| GOBP_REGULATION_OF_FATTY_ACID_BETA_OXIDATION | GOBP_REGULATION_OF_FATTY_ACID_BETA_OXIDATION | GOBP_REGULATION_OF_FATTY_ACID_BETA_OXIDATION | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | CNR1/TWIST1/ABCD2/IRS2/PLIN5 | 5 |
| GOMF_G_PROTEIN_BETA_SUBUNIT_BINDING | GOMF_G_PROTEIN_BETA_SUBUNIT_BINDING | GOMF_G_PROTEIN_BETA_SUBUNIT_BINDING | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | GNG4/RGS7/OPRM1/RGS11/GNG8 | 5 |
| GOMF_PROTEIN_TYROSINE_KINASE_ACTIVATOR_ACTIVITY | GOMF_PROTEIN_TYROSINE_KINASE_ACTIVATOR_ACTIVITY | GOMF_PROTEIN_TYROSINE_KINASE_ACTIVATOR_ACTIVITY | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | TAL1/CD24/NRG3/AFAP1L2/GRM5 | 5 |
| GOMF_SYNTAXIN_1_BINDING | GOMF_SYNTAXIN_1_BINDING | GOMF_SYNTAXIN_1_BINDING | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | CPLX2/STXBP1/VAMP2/UNC13A/SNAP25 | 5 |
| HP_REFLEX_SEIZURE | HP_REFLEX_SEIZURE | HP_REFLEX_SEIZURE | 5/1243 | 20/23056 | 0.2500000 | 4.637168 | 3.884501 | 0.0035497 | 0.0467730 | 0.0411053 | GABRD/SCN1A/GABRG2/KCNQ3/STXBP1 | 5 |
| GOBP_GLIAL_CELL_DIFFERENTIATION | GOBP_GLIAL_CELL_DIFFERENTIATION | GOBP_GLIAL_CELL_DIFFERENTIATION | 22/1243 | 218/23056 | 0.1009174 | 1.871884 | 3.087582 | 0.0035778 | 0.0470933 | 0.0413867 | TAL1/TSPAN2/CNTN2/SOX11/CXCR4/GAP43/KLF15/SOX2/TLR2/SOX4/TTBK1/POU3F2/DLL1/RELN/NTRK2/ROR2/CNTN1/ASCL1/SLC8A3/SPINT1/RNF112/MAPT | 22 |
| GOBP_DENDRITIC_SPINE_MORPHOGENESIS | GOBP_DENDRITIC_SPINE_MORPHOGENESIS | GOBP_DENDRITIC_SPINE_MORPHOGENESIS | 9/1243 | 58/23056 | 0.1551724 | 2.878242 | 3.418858 | 0.0036603 | 0.0481268 | 0.0422950 | KIF1A/CTNND2/RELN/CUX2/CDK5R1/SRCIN1/SHANK1/ZDHHC15/PAK3 | 9 |
| GOBP_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | GOBP_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | GOBP_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | 11/1243 | 80/23056 | 0.1375000 | 2.550442 | 3.316071 | 0.0036731 | 0.0481387 | 0.0423055 | NPPA/GLP1R/GUCA1A/ADCYAP1R1/DEFB1/GAL/PDE2A/KCNC2/AKAP6/GUCY2D/RUNDC3A | 11 |
| GOBP_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | 11/1243 | 80/23056 | 0.1375000 | 2.550442 | 3.316071 | 0.0036731 | 0.0481387 | 0.0423055 | KANK4/ADD2/MAP2/VILL/CRACD/DMTN/TMOD1/CARMIL2/TUBB4A/INPP5J/TMSB4Y | 11 |
| ROSS_AML_WITH_PML_RARA_FUSION | ROSS_AML_WITH_PML_RARA_FUSION | ROSS_AML_WITH_PML_RARA_FUSION | 11/1243 | 80/23056 | 0.1375000 | 2.550442 | 3.316071 | 0.0036731 | 0.0481387 | 0.0423055 | PGBD5/IGFBP2/ST3GAL6/CPA3/STXBP1/CDKN1C/NAALADL1/CCNA1/CLMN/LDLRAD4/S100B | 11 |
| GOBP_MAST_CELL_ACTIVATION | GOBP_MAST_CELL_ACTIVATION | GOBP_MAST_CELL_ACTIVATION | 10/1243 | 69/23056 | 0.1449275 | 2.688213 | 3.352518 | 0.0037418 | 0.0489858 | 0.0430499 | GATA2/KIT/CPLX2/CNR1/SYK/STXBP1/CHGA/VAMP2/PLA2G3/IL13RA2 | 10 |
| CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | 19/1243 | 179/23056 | 0.1061453 | 1.968854 | 3.106315 | 0.0037615 | 0.0491908 | 0.0432301 | CYP2J2/HAAO/AGXT/MYRIP/SLC38A3/ST3GAL6/KNG1/ADH4/C6/F12/GPLD1/ABCB4/RUNDC3B/AZGP1/TFR2/KCNJ8/AMDHD1/CUX2/ABAT | 19 |
| GOMF_CYCLIC_NUCLEOTIDE_BINDING | GOMF_CYCLIC_NUCLEOTIDE_BINDING | GOMF_CYCLIC_NUCLEOTIDE_BINDING | 7/1243 | 38/23056 | 0.1842105 | 3.416861 | 3.559345 | 0.0037755 | 0.0492686 | 0.0432984 | PDE4B/HCN3/KCNH1/RAPGEF4/PRKG2/PDE2A/CNGB1 | 7 |
| REACTOME_GAP_JUNCTION_ASSEMBLY | REACTOME_GAP_JUNCTION_ASSEMBLY | REACTOME_GAP_JUNCTION_ASSEMBLY | 7/1243 | 38/23056 | 0.1842105 | 3.416861 | 3.559345 | 0.0037755 | 0.0492686 | 0.0432984 | TUBA3E/TUBB2A/TUBB2B/TUBA1A/TUBA3C/GJD2/TUBB4A | 7 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | 15/1243 | 128/23056 | 0.1171875 | 2.173673 | 3.178552 | 0.0037825 | 0.0493060 | 0.0433314 | VSNL1/MYRIP/GPR27/TLR2/ISL1/SOX4/GPLD1/RFX6/PLA2G1B/P2RX7/IRS2/ABAT/PARD6A/DOC2B/ABCG1 | 15 |
| LIU_PROSTATE_CANCER_DN | LIU_PROSTATE_CANCER_DN | LIU_PROSTATE_CANCER_DN | 41/1243 | 491/23056 | 0.0835031 | 1.548871 | 2.934632 | 0.0037958 | 0.0494266 | 0.0434373 | VAV3/ANKRD35/DPT/MEIS1/GPR155/SGPP2/RBP1/SPATA18/KIT/ANK2/UBE2QL1/GPLD1/COL9A1/FYN/JAZF1/CCDC136/VSTM4/SORBS1/TSPAN18/TRIM29/ENO2/KCNJ8/TUBA1A/EFS/PRIMA1/SERPINA5/DUOX1/CPLX3/CRABP1/DOK4/HLF/BCL2/ZNF536/WFDC2/NEFH/GPM6B/KLF8/TMEM35A/TCEAL2/GPRASP1/CHRDL1 | 41 |
| PEREZ_TP63_TARGETS | PEREZ_TP63_TARGETS | PEREZ_TP63_TARGETS | 32/1243 | 359/23056 | 0.0891365 | 1.653364 | 2.978368 | 0.0038016 | 0.0494488 | 0.0434569 | RBP7/CELF3/KCNK3/CRYBA2/PPP2R2C/KIT/ACSL1/UBE2QL1/SELENOP/MAP7/ARFGEF3/KDM7A/TNFRSF10D/FAM95C/RASEF/EPB41L4B/CELF2/PSD/CDKN1C/BTBD11/SMAD9/DIO3/ST8SIA2/PRSS33/SLC6A2/DOK4/DOC2B/RAB11FIP4/ELAVL3/PPP1R16B/MAFB/SEPTIN5 | 32 |
| GOBP_VASODILATION | GOBP_VASODILATION | GOBP_VASODILATION | 8/1243 | 48/23056 | 0.1666667 | 3.091445 | 3.462487 | 0.0038397 | 0.0496267 | 0.0436132 | NPPA/ADORA1/KNG1/GUCY1A1/VSTM4/ADRA2A/NOS1/GCH1 | 8 |
| GOCC_INTERCALATED_DISC | GOCC_INTERCALATED_DISC | GOCC_INTERCALATED_DISC | 8/1243 | 48/23056 | 0.1666667 | 3.091445 | 3.462487 | 0.0038397 | 0.0496267 | 0.0436132 | ATP1B1/SLC8A1/SCN1A/SCN5A/ANK2/SCN4B/AKAP6/DSC2 | 8 |
| GOCC_SNARE_COMPLEX | GOCC_SNARE_COMPLEX | GOCC_SNARE_COMPLEX | 8/1243 | 48/23056 | 0.1666667 | 3.091445 | 3.462487 | 0.0038397 | 0.0496267 | 0.0436132 | SYN2/STXBP5L/CPLX1/CPLX2/CPLX3/STX1B/VAMP2/SNAP25 | 8 |
| HP_BROAD_PHILTRUM | HP_BROAD_PHILTRUM | HP_BROAD_PHILTRUM | 8/1243 | 48/23056 | 0.1666667 | 3.091445 | 3.462487 | 0.0038397 | 0.0496267 | 0.0436132 | COLEC11/SOX11/SIX3/SCN1A/SLC6A1/SOX4/KCNK9/NEXMIF | 8 |
| ZHAN_MULTIPLE_MYELOMA_CD2_UP | ZHAN_MULTIPLE_MYELOMA_CD2_UP | ZHAN_MULTIPLE_MYELOMA_CD2_UP | 8/1243 | 48/23056 | 0.1666667 | 3.091445 | 3.462487 | 0.0038397 | 0.0496267 | 0.0436132 | RGS13/SLC8A1/B3GALNT1/CNR1/PAX5/PIK3AP1/PDZRN4/DTX1 | 8 |
| ZHAN_MULTIPLE_MYELOMA_MF_UP | ZHAN_MULTIPLE_MYELOMA_MF_UP | ZHAN_MULTIPLE_MYELOMA_MF_UP | 8/1243 | 48/23056 | 0.1666667 | 3.091445 | 3.462487 | 0.0038397 | 0.0496267 | 0.0436132 | GREB1/SFRP2/TUBB2B/DPYSL2/NTRK2/SYNDIG1/TMPRSS15/GPM6B | 8 |
5.1.2. MES Normoxia
kable(as.data.frame(enrichr_RNA_Normoxia_ADRN_vs_MES_Down), caption="Enricher Output MES Normoxia") %>%
kable_styling("striped", full_width = F, font_size = 12) %>%
scroll_box(width = "100%", height = "400px")| ID | Description | GeneRatio | BgRatio | RichFactor | FoldEnrichment | zScore | pvalue | p.adjust | qvalue | geneID | Count | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_UP | BLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_UP | BLANCO_MELO_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_A594_CELLS_UP | 122/1438 | 286/23056 | 0.4265734 | 6.839414 | 25.628607 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/TNFRSF1B/SPOCD1/ZC3H12A/IFI44L/GBP3/GBP1/GBP2/GBP4/GBP5/CSF1/CTSS/IFI16/LAMC2/NIBAN1/IGFN1/RASGRP3/IL1A/IL1B/AOX1/SERPINE2/SP110/SP140L/SP100/IRAK2/HRH1/CDCP1/TMEM158/UBA7/FSTL1/PARP14/IL1RAP/CXCL8/CXCL1/CXCL2/GPAT3/TNIP3/DDX60/DDX60L/TLR3/IL7R/OSMR/ERAP2/HBEGF/ADAM19/GFPT2/ID4/MICB/RUNX2/NT5E/CRYBG1/LAMA4/TNFAIP3/STX11/RAET1E/SOD2/IL6/SEMA3D/SAMD9/SAMD9L/PARP12/TCAF2/TNFRSF10A/STC1/IDO1/CA13/FBXO32/ST3GAL1/LY6K/PARP10/CD274/DDX58/KLF4/TRAF1/IL15RA/COL13A1/PLAU/PTPRE/NRIP3/CD82/BIRC3/MMP10/MMP1/CASP1/C1S/EMP1/ITGA5/CPM/GLIPR1/NAV3/TMCC3/SELPLG/OASL/LCP1/TNFSF13B/NID2/BCL2A1/ANPEP/IL4R/IL21R/NLRC5/CRISPLD2/CD68/SLFN5/CSF3/KRT17/DHX58/SOCS3/LIPG/SERPINB8/TNFSF14/C3/ICAM1/BMP2/TGM2/SDC4/MX2/MX1/USP18/APOL6/APOL3/APOL1 | 122 |
| CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | 142/1438 | 456/23056 | 0.3114035 | 4.992851 | 22.210868 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/EPHA2/RUNX3/PDZK1IP1/GBP3/GBP1/S100A2/IFI16/LAMC2/PTGS2/PLA2G4A/LAMB3/LBH/TGFA/EVA1A/IL1A/NMI/FAP/CYBRD1/ITGA6/NABP1/SERPINE2/SP100/TWIST2/HRH1/TGFBR2/CDCP1/COL8A1/PHLDB2/CCDC80/FSTL1/WWTR1/MME/FNDC3B/P3H2/IL1RAP/SEL1L3/CXCL1/CXCL3/CXCL2/EREG/ANXA3/CFI/IL15/PDGFC/IL7R/OSMR/CARD6/FST/F2RL1/ELL2/ERAP2/TGFBI/STING1/ADRB2/PXDC1/HLA-E/PSMB8/PSMB9/OGFRL1/CD109/NT5E/CRYBG1/TNFAIP3/PERP/ITGB8/SKAP2/HOXA1/HOXA3/INHBA/SAMD9/MDFIC/CAV2/CAV1/MET/AKR1B10/LOXL2/PLAT/CEBPD/FZD6/EXT1/LY6K/HRCT1/ANXA1/GAS1/AKR1C3/NRP1/ANXA8/PLAU/FAS/HTRA1/ADM/SAA1/CD44/FOSL1/MAML2/YAP1/BIRC3/CASP4/CASP1/CRYAB/NNMT/UBASH3B/C1S/C1R/YBX3/EMP1/SPX/IGFBP6/HMGA2/GLIPR1/MMP14/FRMD6/CCDC9B/MYO1E/ANXA2/BNC1/MFGE8/ALDH1A3/MT2A/MT1X/COTL1/KRT15/KRT17/CAVIN1/DSG2/LIPG/SERPINB2/MBP/C3/ICAM1/FXYD5/AXL/EMP3/SIRPA/PRNP/APOL6/RAC2/MSN/SRPX2/PLS3/GABRE | 142 |
| BLANCO_MELO_BETA_INTERFERON_TREATED_BRONCHIAL_EPITHELIAL_CELLS_UP | BLANCO_MELO_BETA_INTERFERON_TREATED_BRONCHIAL_EPITHELIAL_CELLS_UP | BLANCO_MELO_BETA_INTERFERON_TREATED_BRONCHIAL_EPITHELIAL_CELLS_UP | 121/1438 | 378/23056 | 0.3201058 | 5.132378 | 20.892857 | 0.0000000 | 0.0000000 | 0.0000000 | SPSB1/SPOCD1/GBP3/GBP1/GBP2/GBP5/CSF1/CTSS/IFI16/PTGS2/HSD11B1/WNT9A/RASGRP3/TGFA/IL1A/NMI/SP110/SP140L/SP100/CDCP1/TMEM158/UBA7/ARL14/RTP4/CLDN1/CLDN16/CXCL8/CXCL3/CXCL2/BTC/FGF5/GPAT3/SGMS2/SLC7A11/IL15/CTSO/DDX60L/VEGFC/TRIML2/IL7R/OSMR/ITGA2/FST/ADAMTS6/EDIL3/ERAP2/CSF2/HBEGF/ADRB2/EDN1/TRIM38/TENT5A/NT5E/TNFAIP3/SYNJ2/SOD2/IL6/INHBA/SAMD9/SAMD9L/PDK4/TRIM56/CADPS2/PODXL/ATP6V0A4/PARP12/TNFRSF10A/IDO1/PLAT/MATN2/HAS2/LRATD2/GSDMD/CD274/PDCD1LG2/DDX58/CEMIP2/TNFSF15/IL15RA/FAS/ANKRD1/PTPRE/TRIM5/PAMR1/PLAAT4/SYT12/BIRC3/MMP3/UBASH3B/C1S/C1R/KRT8/PHLDA1/NAV3/DRAM1/LCP1/IRF9/TMEM229B/THBS1/EHD4/BCL2A1/NLRC5/MLKL/SLFN5/SLFN11/DHX58/SOCS3/C3/MUC16/GDF15/AXL/PSG5/RELB/BMP2/TGM2/SDC4/MX1/USP18/APOL6/APOBEC3A/APOBEC3G | 121 |
| HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 89/1438 | 200/23056 | 0.4450000 | 7.134854 | 22.473637 | 0.0000000 | 0.0000000 | 0.0000000 | FUCA1/CCN1/VCAM1/ECM1/PRRX1/LAMC2/CAPG/FAP/COL3A1/COL5A2/FN1/SERPINE2/COL6A3/COL7A1/WNT5A/FSTL1/MYLK/ITGB5/LRRC15/SLIT2/CXCL8/CXCL6/CXCL1/SPP1/IL15/VEGFC/DAB2/ITGA2/EDIL3/TGFBI/SPARC/CAP2/COL12A1/NT5E/GJA1/LAMA2/CCN2/TNFAIP3/THBS2/IL6/INHBA/SERPINE1/MEST/LOXL2/MATN2/CTHRC1/TNFRSF11B/TPM2/GAS1/COL5A1/FZD8/DKK1/FAS/HTRA1/CD44/EFEMP2/SERPINH1/MMP1/MMP3/NNMT/TAGLN/ITGA5/GLIPR1/LUM/POSTN/MMP14/NID2/FBLN5/THBS1/FBN1/TPM1/LOXL1/ANPEP/TNFRSF12A/IL32/MMP2/COL1A1/FSTL3/GADD45B/TGFB1/EMP3/MYL9/TGM2/SDC4/COL6A2/LGALS1/MXRA5/SAT1/BGN | 89 |
| SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | 115/1438 | 353/23056 | 0.3257790 | 5.223339 | 20.623194 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/GBP1/CD53/OLFML3/C1orf54/CTSS/IFI16/FCGR2A/PRRX1/CFH/PTPRC/NID1/IL1R1/FAP/COL3A1/COL5A2/FN1/SERPINE2/ACKR3/COL6A3/TGFBR2/TMEM158/FSTL1/HEG1/PLSCR4/WWTR1/MME/LRRC15/SPON2/KDR/TDO2/C9/DAB2/PPIC/TGFBI/SPARC/ADAM19/GFPT2/PSMB9/RCAN2/ADGRF5/LAMA4/CCN2/THBS2/GPNMB/SKAP2/INHBA/TNS3/RARRES2/MSR1/PDLIM2/LOXL2/SULF1/ZFPM2/COL14A1/CCN4/ANXA1/GAS1/COL5A1/JCAD/NRP1/ALOX5/SRGN/PLAU/FAS/HTRA1/MICAL2/MS4A4A/EFEMP2/SERPINH1/MMP1/MMP3/CASP1/NNMT/C1S/C1R/C3AR1/EMP1/GLIPR1/LUM/NUAK1/POSTN/SLC7A7/NID2/DACT1/AHNAK2/FBN1/LOXL1/MMP2/MAF/CRISPLD2/CCL5/CAVIN1/COPZ2/COL1A1/MRC2/PECAM1/KCNJ2/SLC16A3/COLEC12/FXYD5/AXL/APOE/EMP3/PRNP/MYL9/TGM2/COL6A2/HMOX1/LGALS1/MXRA5/MSN/SRPX2/PLS3/BGN | 115 |
| GOCC_COLLAGEN_CONTAINING_EXTRACELLULAR_MATRIX | GOCC_COLLAGEN_CONTAINING_EXTRACELLULAR_MATRIX | GOCC_COLLAGEN_CONTAINING_EXTRACELLULAR_MATRIX | 121/1438 | 427/23056 | 0.2833724 | 4.543417 | 19.061529 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/MMP23B/HSPG2/TINAGL1/PODN/CCN1/ECM1/ADAMTSL4/CTSS/S100A10/LAMC2/HMCN1/PRG4/PRELP/LAMB3/TGFB2/AGT/NID1/LTBP1/VIT/EFEMP1/COL3A1/COL5A2/FN1/SERPINE2/COL6A3/COL7A1/LAMB2/SEMA3B/WNT5A/COL8A1/CCDC80/P3H2/LRRC15/SOD3/AMTN/ADAMTS3/NPNT/HAPLN1/EDIL3/TGFBI/SPARC/ADAM19/ADAMTS2/SERPINB1/COL21A1/COL19A1/COL12A1/LAMA4/LAMA2/CCN2/THBS2/SERPINE1/COL26A1/PTPRZ1/RARRES2/SHH/LOXL2/CLU/PLAT/SULF1/MATN2/CTHRC1/ANGPT1/COL14A1/ANXA1/COL27A1/FIBCD1/COL5A1/ANXA8/MBL2/COL13A1/MMRN2/FGFR2/HTRA1/EFEMP2/SERPINH1/APOC3/APOA1/ADAMTS8/ADAMTS15/VWF/LUM/POSTN/FREM2/NID2/LTBP2/FBLN5/SERPINA1/THBS1/FBN1/ANXA2/LOXL1/CSPG4/MFGE8/MMP2/CDH13/COL1A1/ITGB4/EMILIN2/SERPINB8/ELANE/ICAM1/GDF15/TGFB1/BCAM/APOE/TGM2/COL9A3/ADAMTS5/COL18A1/COL6A2/LGALS1/PDGFB/MXRA5/NDP/SRPX2/COL4A6/COL4A5/GPC4/BGN | 121 |
| ONDER_CDH1_TARGETS_2_DN | ONDER_CDH1_TARGETS_2_DN | ONDER_CDH1_TARGETS_2_DN | 124/1438 | 473/23056 | 0.2621564 | 4.203254 | 18.154545 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/TINAGL1/ZC3H12A/S100A2/LAMC2/PTGS2/PLA2G4A/ATP2B4/LAMB3/TGFA/IL1A/IL1B/IL36G/ITGB6/GALNT3/ITGA6/TMEM40/CDCP1/SEMA3B/SLC12A8/P3H2/CLDN1/IL1RAP/HES1/FGFR3/SEL1L3/ARAP2/RBM47/CXCL8/CXCL1/CXCL3/CXCL2/EREG/ANXA3/CDS1/ABCG2/INPP4B/DDX60/IRX4/ITGA2/FST/PLK2/CSF2/HBEGF/ADRB2/SERPINB1/DSP/ADTRP/EDN1/IER3/DDR1/TNFRSF21/CRYBG1/TPD52L1/TNFAIP3/PERP/HOXA1/INHBA/SEMA3C/SEMA3A/PTPRZ1/PARP12/ARHGEF5/DDX58/AQP3/PTPN3/IL15RA/ANXA8/PLAU/FGFR2/PTPRE/EPS8L2/SAA1/PRRG4/EHF/CD44/CD82/P2RY2/RAB38/BIRC3/MMP10/MMP1/CASP1/MPZL2/SCNN1A/GPRC5A/ARHGDIB/BHLHE41/KRT8/KRT18/NAV3/FOS/SERPINA1/MYO1E/CA12/ALDH1A3/IL4R/CLDN7/CSF3/KRT13/KRT15/KRT17/JUP/SOX9/ITGB4/RHBDF2/DSG2/SERPINB7/SERPINB2/MBP/C3/ICAM1/CYP4F11/B3GNT3/LYPD3/KCNN4/SIRPA/BMP2/THBD/SDC4/BACE2/CELSR1/ITM2A/ZNF185 | 124 |
| CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | 123/1438 | 466/23056 | 0.2639485 | 4.231986 | 18.178525 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/EPHA2/NEXN/S100A2/IFI16/PTGS2/TGFB2/LBH/CRIM1/CYP26B1/EVA1A/TFPI/CAVIN2/SERPINE2/COL6A3/TWIST2/IRAK2/HRH1/TGFBR2/TMEM158/GXYLT2/PHLDB2/FSTL1/MYLK/HEG1/WWTR1/P3H2/SLIT2/CXCL2/ARSJ/FAT4/IL15/PDGFC/ADAMTS12/RAI14/IL7R/OSMR/C9/DAB2/FST/EDIL3/TGFBI/SPARC/GFPT2/FOXC1/SERPINB1/PSMB9/RUNX2/NT5E/GJA1/TNFAIP3/FAM20C/PDGFA/IL6/FAM126A/INHBA/SEMA3A/SERPINE1/MDFIC/CAV2/CAV1/MET/FLNC/LOXL2/PLAT/EXT1/HAS2/GLIS3/HRCT1/ANXA1/PAPPA/COL5A1/AKR1C3/NRP1/SRGN/COL13A1/PLAU/VCL/ZCCHC24/FAS/ITPRIP/HTRA1/CD44/EFEMP2/FOSL1/MAML2/CASP1/LAYN/NNMT/UBASH3B/C1S/IGFBP6/MSRB3/HMGA2/GLIPR1/NAV3/ZIC2/PYGL/NID2/LTBP2/AHNAK2/FBN1/ANXA2/TPM1/LOXL1/MFGE8/MMP2/CAVIN1/MRC2/SOCS3/EMILIN2/ALPK2/FXYD5/AXL/TGFB1/EMP3/IL11/PRNP/APCDD1L/ADAMTS5/COL6A2/MID1/MSN | 123 |
| DELYS_THYROID_CANCER_UP | DELYS_THYROID_CANCER_UP | DELYS_THYROID_CANCER_UP | 120/1438 | 445/23056 | 0.2696629 | 4.323608 | 18.259302 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/DHRS3/EPHA2/ECE1/PDZK1IP1/GBP2/ECM1/CTSS/S100A10/S100A11/S100A5/S100A2/S100A13/CRABP2/FCGR2A/LAMC2/ELF3/LAMB3/TGFA/CAPG/DPP4/FAP/COL3A1/COL5A2/NRP2/FN1/EPHA4/BHLHE40/COL8A1/ITGB5/CLDN1/IL1RAP/SEL1L3/CXCL8/CXCL2/EREG/SPP1/CFI/TDO2/ITGA2/ATP10B/RREB1/DSP/IER3/ITPR3/TNFRSF21/NT5E/CRYBG1/THBS2/INHBA/MET/MSR1/TNFRSF10C/LOXL2/PLAG1/HAS2/ANXA1/TNFSF15/ALOX5/ANXA8/COL13A1/PLAU/FAS/PTPRE/SLC22A18/PHLDA2/ADM/CD44/PLAAT3/ALDH3B1/PRSS23/MMP1/MPZL2/OPCML/TNFRSF1A/C3AR1/ARHGDIB/EPS8/IGFBP6/NCKAP1L/HMGA2/ALOX5AP/SERPINA1/AHNAK2/THBS1/ANXA2/BCL2A1/MFGE8/ALDH1A3/CLDN7/GRB7/KRT13/KRT15/KRT19/KRT17/ITGA3/COL1A1/ABCC3/MRC2/EMILIN2/FSTL3/C3/ICAM1/GDF15/SCN1B/FXYD5/KCNN4/APOE/EMP3/RRAS/KLK6/TGM2/SDC4/BIRC7/RUNX1/LIF/HMOX1/LGALS1/KDELR3/IL13RA1 | 120 |
| VERHAAK_GLIOBLASTOMA_MESENCHYMAL | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | 82/1438 | 216/23056 | 0.3796296 | 6.086746 | 19.371941 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/PTPN22/C1orf54/S100A11/S100A13/FCGR2A/PTPRC/LTBP1/VAMP5/IL1R1/KYNU/CYBRD1/ITGA4/CASP8/SP100/TGFBR2/CDCP1/STAB1/WWTR1/FNDC3B/RBM47/TEC/ARSJ/DAB2/TGFBI/TRIM38/HFE/RUNX2/CRYBG1/TNFAIP3/SERPINE1/MSR1/ANXA1/COL5A1/IL15RA/NRP1/ALOX5/PLAU/MYOF/MS4A4A/EFEMP2/ALDH3B1/YAP1/CASP4/CASP1/TNFRSF1A/IGFBP6/ITGA5/STAT6/DRAM1/LCP1/PYGL/LTBP2/SERPINA1/THBS1/ANXA2/IL4R/CAVIN1/FMNL1/COPZ2/COL1A1/MRC2/SLC16A3/TNFRSF11A/CNN2/FXYD5/BLVRB/RELB/C5AR1/EHD2/EMP3/RRAS/THBD/PROCR/CEBPB/MYH9/RAC2/CYTH4/LGALS1/SAT1/SRPX2/PLS3 | 82 |
| BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_CALU3_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_CALU3_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_CALU3_CELLS_UP | 102/1438 | 339/23056 | 0.3008850 | 4.824203 | 18.294457 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/EDN2/IFI44L/GBP1/GBP4/GBP5/VCAM1/CSF1/IFI16/PTGS2/NUAK2/NLRP3/RASGRP3/IL1A/IL1B/FAP/CAVIN2/SP110/SP100/IRAK2/PHLDB2/PARP14/AMOTL2/RTP4/CXCL8/CXCL3/CXCL2/DDX60/DDX60L/TLR3/ADAMTS6/CSF2/HBEGF/ADRB2/H1-3/RUNX2/TENT5A/DDO/LAMA2/CCN2/TNFAIP3/STX11/IL6/INHBA/SEMA3A/SAMD9/SAMD9L/SERPINE1/PARP12/GIMAP2/IDO1/TCIM/PLAT/TNFRSF11B/PARP10/CD274/PDCD1LG2/DDX58/KLF4/TRAF1/IL15RA/MAP3K8/ANKRD1/IFITM2/TRIM5/SLC15A3/BIRC3/CASP1/C1R/RND1/NAV3/OASL/TRPC4/TNFSF13B/NFKBIA/SERPINA10/TNFAIP2/THBS1/BCL2A1/NUPR1/MT2A/NLRC5/SLFN5/CCL5/CSF3/DHX58/IFI35/C1QTNF1/SERPINB7/SERPINB2/TNFSF14/ICAM1/ZFP36/PLA2G4C/BMP2/MX2/MX1/USP18/APOL6/APOL3/CYTH4/APOBEC3G | 102 |
| REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | 96/1438 | 301/23056 | 0.3189369 | 5.113636 | 18.527846 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/VCAM1/ITGA10/CTSS/LAMC2/OPTC/LAMB3/TGFB2/NID1/LTBP1/EFEMP1/BMP10/ITGB6/ITGA6/ITGA4/COL3A1/COL5A2/FN1/COL6A3/COL7A1/LAMB2/COL8A1/ITGB5/P3H2/KDR/ADAMTS3/SPP1/ADAMTS16/ITGA2/HAPLN1/SPARC/ADAM19/ADAMTS2/DDR1/COL21A1/COL19A1/COL12A1/LAMA4/LAMA2/PDGFA/ITGB8/SERPINE1/COL26A1/LOXL2/ADAM9/COL14A1/COL27A1/COL5A1/ITGA8/COL13A1/TLL2/LOXL4/HTRA1/CD44/EFEMP2/P4HA3/SERPINH1/MMP10/MMP1/MMP3/ADAMTS8/VWF/ITGA5/ITGA7/LUM/MMP14/NID2/BMP4/LTBP2/FBLN5/THBS1/FBN1/ITGA11/LOXL1/MMP2/CTRB1/ADAMTS18/ITGA3/COL1A1/PECAM1/ITGB4/EMILIN2/ELANE/ICAM1/TGFB1/BMP2/SDC4/COL9A3/ADAMTS5/COL18A1/COL6A2/PDGFB/COL4A6/COL4A5/BGN | 96 |
| BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | 111/1438 | 428/23056 | 0.2593458 | 4.158190 | 17.009488 | 0.0000000 | 0.0000000 | 0.0000000 | HSPB7/SYNC/GBP2/VCAM1/CTSS/FMO3/PRG4/CFH/PRELP/CD34/TGFB2/CYP26B1/LRP1B/ITGA4/TFPI/FN1/SERPINE2/ACKR3/BHLHE40/PPARG/WNT5A/MITF/EPHA3/SEL1L3/CXCL8/CXCL1/CXCL3/CXCL2/CFI/SLC7A11/TLR3/MYO10/NPR3/RAI14/FOXD1/HAPLN1/HBEGF/DSP/TPD52L1/MOXD1/TNFAIP3/SOD2/GPNMB/INHBA/PDK4/SERPINE1/MET/FLNC/PODXL/LOXL2/TCIM/MYBL1/SULF1/MATN2/TNFRSF11B/COL14A1/TPM2/KLF4/PAPPA/GSN/NACC2/CLIC3/IL15RA/MAP3K8/DKK1/SRGN/PAPSS2/PPP1R3C/ACSL5/MICAL2/CD44/MMP1/GPRC5A/ARHGDIB/RND1/KRT7/KRT18/GLIPR1/IGF1/OASL/TRPC4/FOXO1/EDNRB/PRKD1/NFKBIA/CRIP1/ACTC1/THBS1/CES1/RRAD/NQO1/MAF/ABCA6/SLC16A3/COLEC12/MOCOS/GADD45B/GDF15/ZFP36/APOE/BMP2/TGM2/DOK5/MX2/MX1/COL18A1/APOL3/ITM2A/SRPX2/COL4A5/TENM1 | 111 |
| LINDGREN_BLADDER_CANCER_CLUSTER_2B | LINDGREN_BLADDER_CANCER_CLUSTER_2B | LINDGREN_BLADDER_CANCER_CLUSTER_2B | 105/1438 | 389/23056 | 0.2699229 | 4.327776 | 17.072067 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/CCN1/VCAM1/C1orf54/PRRX1/PTPN7/LBH/EFEMP1/ACTG2/IL1A/CYBRD1/ITGA4/COL5A2/NRP2/COL6A3/TMEM158/LAMB2/CCDC80/MYLK/AMOTL2/LEF1/IL7R/DAB2/IQGAP2/EDIL3/SPARC/ADAM19/DOCK2/HLA-E/RUNX2/RCAN2/ADGRF5/LAMA4/CCN2/MOXD1/TNFAIP3/THBS2/FAM126A/AQP1/CAV1/PODXL/RARRES2/PDGFRL/PNOC/TPM2/KLF4/PAPPA/TRAF1/GSN/NEK6/SRGN/HHEX/IFITM2/IFITM3/MICAL2/MS4A4A/BIRC3/NNMT/C1S/C1R/C3AR1/GLIPR1/LUM/NUAK1/LATS2/ALOX5AP/POSTN/LCP1/NFKBIA/NID2/CRIP1/TPM1/RBPMS2/BCL2A1/ANPEP/IL32/MMP2/MT2A/MT1X/MAF/COTL1/CRISPLD2/FOXF1/SLFN11/CAVIN1/COPZ2/PECAM1/SOCS3/COLEC12/GADD45B/EBI3/ICAM1/IL27RA/EMP3/SIRPA/THBD/MYL9/COL18A1/COL6A2/RAC2/CYTH4/LGALS2/LGALS1/MSN/ITM2A | 105 |
| FOROUTAN_TGFB_EMT_UP | FOROUTAN_TGFB_EMT_UP | FOROUTAN_TGFB_EMT_UP | 73/1438 | 192/23056 | 0.3802083 | 6.096025 | 18.287750 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/LBH/COL3A1/COL5A2/FN1/SERPINE2/ACKR3/COL6A3/BHLHE40/HRH1/COL7A1/WNT5A/VGLL3/SLCO2A1/FAM114A1/INPP4B/PDGFC/GASK1B/VEGFC/MYO10/ADAMTS6/FOXD1/TGFBI/SPARC/GALNT10/ADAM19/GFPT2/PXDC1/RUNX2/NT5E/PTPRK/CCN2/PDGFA/INHBA/SEMA3C/SERPINE1/PODXL/STC1/COL5A1/HTRA1/NRIP3/MICAL2/MMP10/MMP1/TAGLN/AMIGO2/ITGA5/HMGA2/GLIPR1/LUM/NUAK1/ALOX5AP/POSTN/DACT1/PLEK2/THBS1/FBN1/TPM1/MMP2/MAF/HS3ST3A1/COL1A1/MRC2/FSTL3/GADD45B/TGFB1/IL11/BMP2/MYL9/TGM2/MN1/HMOX1/KDELR3 | 73 |
| REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 106/1438 | 407/23056 | 0.2604423 | 4.175770 | 16.671548 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/RHOC/ECM1/S100A10/S100A13/ELF3/LBH/EFEMP1/CAPG/FAP/COL5A2/FN1/SERPINE2/TGFBR2/COL8A1/FSTL1/MYLK/TM4SF1/FNDC3B/LPP/ARSJ/PDGFC/VEGFC/RAI14/OSMR/DAB2/EDIL3/ELL2/PPIC/GRAMD2B/TGFBI/ADAMTS2/PXDC1/TAPBP/TPBG/NT5E/LAMA4/GJA1/CCN2/THBS2/SKAP2/INHBA/SEMA3C/FZD1/CAV2/CAV1/ZYX/PDLIM2/LOXL2/CLU/ADAM9/PLAT/EXT1/TNFRSF11B/B4GALT1/ANXA1/GSN/COL5A1/NRP1/PLAU/PAPSS2/BAG3/HTRA1/CREB3L1/EFEMP2/CASP4/NNMT/TNFRSF1A/C1S/EMP1/IGFBP6/ITGA5/STAT6/GLIPR1/DRAM1/MMP14/PRKD1/FBLN5/THBS1/FBN1/ANXA2/LOXL1/MFGE8/RHBDF1/TNFRSF12A/MMP2/NQO1/CAVIN1/COPZ2/COL1A1/MRC2/WIPI1/FSTL3/CNN2/KLF2/FXYD5/AXL/TGFB1/RRAS/COL6A2/MYH9/KDELR3/MSN/SRPX2/PLS3/IL13RA1 | 106 |
| GOBP_EXTERNAL_ENCAPSULATING_STRUCTURE_ORGANIZATION | GOBP_EXTERNAL_ENCAPSULATING_STRUCTURE_ORGANIZATION | GOBP_EXTERNAL_ENCAPSULATING_STRUCTURE_ORGANIZATION | 92/1438 | 313/23056 | 0.2939297 | 4.712687 | 17.056536 | 0.0000000 | 0.0000000 | 0.0000000 | MMP23B/TNFRSF1B/TIE1/CCN1/ADAMTSL4/CTSS/HMCN1/ELF3/OPTC/LAMB3/TGFB2/AGT/NID1/VIT/CAPG/DPP4/FAP/COL3A1/COL5A2/LAMB2/COL8A1/PHLDB2/CCDC80/ADAMTS3/NPNT/ADAMTS16/ADAMTS12/ADAMTS6/TGFBI/ADAMTS2/FOXC1/ADTRP/DDR1/COL19A1/COL12A1/CCN2/IL6/CAV2/CAV1/CSGALNACT1/LOXL2/SULF1/EXT1/TNFRSF11B/COL14A1/HAS2/B4GALT1/COL27A1/GSN/COL5A1/NOTCH1/ITGA8/COL13A1/TLL2/LOXL4/NFKB2/WT1/CREB3L1/EFEMP2/SERPINH1/MMP10/MMP1/MMP3/ADAMTS8/ADAMTS15/TNFRSF1A/LUM/POSTN/LCP1/MMP14/NID2/FBLN5/MYO1E/LOXL1/MMP2/ADAMTS18/CRISPLD2/FOXF1/COL1A1/SOX9/ELANE/ADAMTSL5/TGFB1/BCL3/HAS1/BMP2/COL9A3/ADAMTS5/RUNX1/COL18A1/COL4A6/COL4A5 | 92 |
| BLANCO_MELO_HUMAN_PARAINFLUENZA_VIRUS_3_INFECTION_A594_CELLS_UP | BLANCO_MELO_HUMAN_PARAINFLUENZA_VIRUS_3_INFECTION_A594_CELLS_UP | BLANCO_MELO_HUMAN_PARAINFLUENZA_VIRUS_3_INFECTION_A594_CELLS_UP | 74/1438 | 204/23056 | 0.3627451 | 5.816030 | 17.819536 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP3/GBP1/GBP4/GBP5/CTSS/IFI16/LAMC2/NIBAN1/RASGRP3/IL1A/IL1B/NMI/EPHA4/SP110/SP140L/SP100/CDCP1/UBA7/PARP14/RTP4/EREG/DDX60/DDX60L/TLR3/ITGA2/FST/ERAP2/GMPR/TRIM38/RUNX2/NT5E/CRYBG1/TNFAIP3/RAET1E/IL6/BMPER/SEMA3D/SAMD9/SAMD9L/PODXL/PARP12/STC1/IDO1/PARP10/CD274/DDX58/KLF4/TRAF1/IL15RA/MYPN/IFITM3/TRIM5/SLC15A3/FZD4/BIRC3/CASP1/C1S/GLIPR1/PHLDA1/OASL/TNFSF13B/IRF9/NLRC5/CD68/DHX58/IL4I1/TGM2/MX2/MX1/USP18/APOL6/APOL3/APOL1 | 74 |
| WANG_SMARCE1_TARGETS_UP | WANG_SMARCE1_TARGETS_UP | WANG_SMARCE1_TARGETS_UP | 88/1438 | 295/23056 | 0.2983051 | 4.782839 | 16.865041 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/SPOCD1/NEXN/PRRX1/HMCN1/PRG4/CFH/TGFB2/NID1/LBH/IL1R1/FAP/CYBRD1/COL3A1/FN1/COL6A3/COL8A1/MYLK/ITGB5/HEG1/SLC12A8/PLSCR4/LPP/SEL1L3/CFI/PCDH10/TDO2/NPR3/DAB2/ITGA2/IQGAP2/EDIL3/TGFBI/CD109/COL12A1/TPBG/TBX18/PERP/ITGB8/FZD1/ZNF703/TCIM/PLAT/PLAG1/SULF1/MATN2/CTHRC1/FBXO32/CCN4/CEMIP2/S1PR3/GSN/FIBCD1/COL5A1/JCAD/MAP3K8/TLL2/WT1/TAGLN/C1S/AMIGO2/KRT18/IGFBP6/LUM/TNFRSF19/POSTN/FOXO1/NID2/DACT1/DIO2/CGNL1/CA12/NUPR1/MMP2/LPCAT2/MYOCD/SLFN5/HOXB7/COL1A1/SOCS3/DSG2/SERPINB7/TGFB1/BCAM/MYL9/BACE2/ITM2A/IL13RA1 | 88 |
| BOQUEST_STEM_CELL_UP | BOQUEST_STEM_CELL_UP | BOQUEST_STEM_CELL_UP | 81/1438 | 262/23056 | 0.3091603 | 4.956885 | 16.612998 | 0.0000000 | 0.0000000 | 0.0000000 | OLFML3/CRABP2/PRRX1/NIBAN1/PLA2G4A/CFH/PRELP/TGFB2/EFEMP1/HNMT/LRP1B/FAP/CYBRD1/COL3A1/COL5A2/AOX1/SERPINE2/COL6A3/SUSD5/WNT5A/MITF/MME/SPON2/SLIT2/FST/GFPT2/NT5E/LAMA2/UST/THBS2/GPNMB/INHBA/SEMA3C/MEST/PDGFRL/MSC/ANGPT1/COL14A1/GAS1/GSN/COL5A1/ITGA8/HTRA1/PHLDA2/CD44/PAMR1/CRYAB/C1S/C1R/RERGL/BHLHE41/IGFBP6/LUM/IGF1/LTBP2/FBLN5/CRIP1/FBN1/ANPEP/MMP2/CES1/CRISPLD2/COL1A1/MRC2/ABCA8/ABCA6/SOX9/COLEC12/MBP/C3/AXL/APOE/EMP3/HAS1/PTGIS/CEBPB/COL6A2/LIF/MXRA5/TENM1/GPC4 | 81 |
| FOROUTAN_PRODRANK_TGFB_EMT_UP | FOROUTAN_PRODRANK_TGFB_EMT_UP | FOROUTAN_PRODRANK_TGFB_EMT_UP | 68/1438 | 185/23056 | 0.3675676 | 5.893350 | 17.234705 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/LBH/FN1/SERPINE2/ACKR3/BHLHE40/HRH1/COL7A1/WNT5A/SLCO2A1/FAM114A1/INPP4B/PDGFC/GASK1B/VEGFC/MYO10/ADAMTS6/FOXD1/TGFBI/SPARC/GALNT10/ADAM19/GFPT2/PXDC1/RUNX2/NT5E/PTPRK/CCN2/PDGFA/INHBA/SEMA3C/SERPINE1/PODXL/STC1/COL5A1/HTRA1/NRIP3/MICAL2/MMP10/MMP1/TAGLN/AMIGO2/ITGA5/HMGA2/GLIPR1/NUAK1/ALOX5AP/POSTN/DACT1/PLEK2/THBS1/FBN1/TPM1/MMP2/MAF/HS3ST3A1/COL1A1/MRC2/FSTL3/GADD45B/TGFB1/IL11/BMP2/MYL9/TGM2/MN1/HMOX1/KDELR3 | 68 |
| HALLMARK_TNFA_SIGNALING_VIA_NFKB | HALLMARK_TNFA_SIGNALING_VIA_NFKB | HALLMARK_TNFA_SIGNALING_VIA_NFKB | 69/1438 | 200/23056 | 0.3450000 | 5.531516 | 16.600174 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/SPSB1/ZC3H12A/CCN1/CSF1/PTGS2/LAMB3/IL1A/IL1B/KYNU/ACKR3/BHLHE40/BCL6/HES1/CXCL6/CXCL1/CXCL3/CXCL2/IL7R/PLK2/F2RL1/CSF2/HBEGF/GFPT2/EDN1/IER3/TNFAIP3/SOD2/IL6/INHBA/SERPINE1/CEBPD/MSC/DDX58/B4GALT1/KLF4/TRAF1/IL15RA/MAP3K8/PLAU/NFKB2/PTPRE/PHLDA2/CD44/FOSL1/BIRC3/PHLDA1/DRAM1/NFKBIA/FOS/TNFAIP2/BCL2A1/CCL5/SOCS3/SERPINB2/SERPINB8/GADD45B/TNFSF9/ICAM1/KLF2/ZFP36/BCL3/RELB/BMP2/SDC4/CEBPB/ICOSLG/LIF/SAT1 | 69 |
| PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | 62/1438 | 162/23056 | 0.3827160 | 6.136232 | 16.919812 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/ECE1/GBP2/LAMC2/PLA2G4A/EFEMP1/CAPG/FAP/COL8A1/ITGB5/CXCL8/CXCL1/ANXA3/VEGFC/TGFBI/BMP6/CAP2/IER3/TNFRSF21/ADGRG6/IL6/SERPINE1/LOXL2/CLU/EXT1/TPM2/DKK1/SRGN/PLAU/CD44/MMP1/NNMT/TAGLN/ARHGDIB/EPS8/KRT7/ITGA5/STAT6/NUAK1/FLT1/SLC7A7/MMP14/LTBP2/AHNAK2/TPM1/ANPEP/IL32/IL4R/MT1X/CLDN7/ICAM1/AXL/EMP3/RRAS/PRNP/PROCR/TGM2/HMOX1/RAC2/ITM2A/SRPX2/BGN | 62 |
| FOROUTAN_INTEGRATED_TGFB_EMT_UP | FOROUTAN_INTEGRATED_TGFB_EMT_UP | FOROUTAN_INTEGRATED_TGFB_EMT_UP | 53/1438 | 118/23056 | 0.4491525 | 7.201433 | 17.418452 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/FN1/SERPINE2/ACKR3/COL6A3/COL7A1/WNT5A/PDGFC/GASK1B/ADAMTS6/FOXD1/TGFBI/SPARC/GALNT10/ADAM19/GFPT2/NT5E/PTPRK/CCN2/INHBA/SERPINE1/PODXL/STC1/COL5A1/HTRA1/MMP10/MMP1/TAGLN/ITGA5/GLIPR1/LUM/NUAK1/ALOX5AP/POSTN/DACT1/PLEK2/THBS1/FBN1/TPM1/MMP2/MAF/HS3ST3A1/COL1A1/MRC2/FSTL3/GADD45B/TGFB1/IL11/MYL9/TGM2/MN1/HMOX1 | 53 |
| NABA_CORE_MATRISOME | NABA_CORE_MATRISOME | NABA_CORE_MATRISOME | 80/1438 | 275/23056 | 0.2909091 | 4.664256 | 15.765945 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/TINAGL1/PODN/CCN1/ECM1/LAMC2/HMCN1/PRG4/PRELP/OPTC/LAMB3/NID1/LTBP1/CRIM1/VIT/EFEMP1/COL3A1/COL5A2/FN1/COL6A3/COL7A1/LAMB2/COL8A1/IGSF10/SPON2/SLIT2/SPP1/NPNT/HAPLN1/EDIL3/TGFBI/SPARC/COL21A1/COL19A1/COL12A1/LAMA4/RSPO3/LAMA2/CCN2/THBS2/BMPER/COL26A1/MATN2/CTHRC1/RSPO2/COL14A1/CCN4/COL27A1/COL5A1/SRGN/COL13A1/MMRN2/TECTB/EFEMP2/VWA5A/VWF/IGFBP6/EPYC/LUM/POSTN/NID2/LTBP2/FBLN5/THBS1/FBN1/GLDN/HAPLN3/MFGE8/CRISPLD2/COL1A1/EMILIN2/COL9A3/COL18A1/COL6A2/MXRA5/SRPX2/COL4A6/COL4A5/BGN | 80 |
| BLANCO_MELO_COVID19_BRONCHIAL_EPITHELIAL_CELLS_SARS_COV_2_INFECTION_UP | BLANCO_MELO_COVID19_BRONCHIAL_EPITHELIAL_CELLS_SARS_COV_2_INFECTION_UP | BLANCO_MELO_COVID19_BRONCHIAL_EPITHELIAL_CELLS_SARS_COV_2_INFECTION_UP | 58/1438 | 144/23056 | 0.4027778 | 6.457889 | 16.944498 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/PDZK1IP1/GBP5/IKBKE/IL1B/IL36G/IRAK2/COL8A1/CXCL8/CXCL6/CXCL1/CXCL5/CXCL2/TRIML2/IL7R/CSF2/HBEGF/ADRB2/SERPINB1/EDN1/IER3/VNN1/TNFAIP3/SOD2/IL6/INHBA/PARP12/CSGALNACT1/STC1/TCIM/PLAT/MAP3K8/NFKB2/IFITM3/MYEOV/BIRC3/MMP1/C1S/C1R/RND1/DRAM1/IRF9/NFKBIA/TNFAIP2/IL32/CSF3/IFI35/SOCS3/C1QTNF1/TNFSF14/C3/ICAM1/BCL3/RELB/BMP2/TGM2/LIF/PDGFB | 58 |
| WU_CELL_MIGRATION | WU_CELL_MIGRATION | WU_CELL_MIGRATION | 65/1438 | 183/23056 | 0.3551913 | 5.694916 | 16.445462 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/CCN1/S100A2/PTGS2/EFEMP1/CAPG/IL1A/KYNU/GALNT3/FN1/WNT5A/TM4SF1/WWTR1/CXCL1/PLAC8/PDGFC/F2RL1/ERAP2/GRAMD2B/TGFBI/TNFRSF21/CRYBG1/GJA1/PERP/SERPINE1/MEST/PODXL/LOXL2/CLU/RBPMS/AQP3/TPM2/AKR1C3/ANXA8/SRGN/EHF/FOSL1/NNMT/SCNN1A/ARHGDIB/EPS8/KRT7/KRT18/IGFBP6/HMGA2/GLIPR1/TNFAIP2/AHNAK2/THBS1/MT2A/MT1X/CLDN7/KRT19/KRT17/JUP/SOX9/ITGB4/AXL/EMP3/SIRPA/TGM2/COL18A1/COL6A2/RAC2/MSN | 65 |
| LIM_MAMMARY_STEM_CELL_UP | LIM_MAMMARY_STEM_CELL_UP | LIM_MAMMARY_STEM_CELL_UP | 107/1438 | 480/23056 | 0.2229167 | 3.574108 | 14.698671 | 0.0000000 | 0.0000000 | 0.0000000 | C1QTNF12/HSPG2/TINAGL1/TIE1/PODN/PRRX1/PTGS2/LMOD1/LGR6/LAMB3/OSR1/LBH/VIT/ACTG2/EVA1A/IL1B/GYPC/ITGA6/COL5A2/CAVIN2/NRP2/TWIST2/RARB/UCN2/COL7A1/PRICKLE2/VGLL3/MYLK/HEG1/MME/P3H2/FGFRL1/SLIT2/ARHGAP24/IRX4/SEMA5A/FST/ARSI/ADAMTS2/PXDC1/ID4/PLA2G7/COL12A1/NT5E/GJA1/CCN2/PDGFA/IL6/CD36/SEMA3C/CAV1/FLNC/MEST/RARRES2/RBPMS/SULF1/MATN2/EXT1/COL14A1/HAS2/TPM2/GSN/COL5A1/NRP1/FZD8/SRGN/FAS/ANKRD1/PPP1R3C/BAG3/HTRA1/PTPRE/MICAL2/PAMR1/SERPINH1/CRYAB/NNMT/TAGLN/IGFBP6/MSRB3/POSTN/EDNRB/THBS1/CSPG4/BNC1/MMP2/CDH13/MYOCD/HS3ST3A1/ITGB4/CD70/ICAM1/CNN1/WTIP/AXL/APOE/PRNP/MYL9/MAP3K7CL/COL18A1/CARD10/LGALS1/CSDC2/CHST7/STARD8/ITM2A/PLS3 | 107 |
| MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | 73/1438 | 235/23056 | 0.3106383 | 4.980582 | 15.818576 | 0.0000000 | 0.0000000 | 0.0000000 | HSPB7/SPOCD1/SYNC/PRRX1/LTBP1/ACTG2/IL1R1/LYPD6B/GALNT5/COL3A1/NABP1/DNER/TMEM158/PRICKLE2/VGLL3/COL8A1/CCDC80/MME/CXCL8/EREG/INPP4B/GASK1B/SEMA5A/ADAMTS12/OSMR/DAB2/FST/FOXD1/ELL2/SPARC/ADAM19/GFPT2/SLC22A23/ITGB8/IL6/FAM126A/GPNMB/PDE1C/SEMA3C/ARHGEF5/LOXL2/STC1/MATN2/ANGPT1/TNFRSF11B/HAS2/FIBCD1/COL5A1/NRP1/DKK1/PLAU/PLPP4/C10orf90/ADM/MICAL2/FIBIN/CD44/AMIGO2/HMGA2/LUM/TNFRSF19/MMP14/NID2/CA12/ITGA11/ALDH1A3/GATA6/SERPINB7/DOK5/APCDD1L/ADAMTS5/LIF/CHST7 | 73 |
| RODWELL_AGING_KIDNEY_UP | RODWELL_AGING_KIDNEY_UP | RODWELL_AGING_KIDNEY_UP | 109/1438 | 500/23056 | 0.2180000 | 3.495277 | 14.548792 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/LDLRAP1/GBP5/VCAM1/CD53/PTPN22/PTPRC/RASSF5/TFPI/COL3A1/FN1/SERPINE2/IRAK2/SHISA5/STAB1/PARP14/TM4SF18/CLDN1/SPON2/SEL1L3/JCHAIN/CXCL1/GASK1B/VEGFC/OSMR/TGFBI/STING1/DOCK2/HLA-E/PSMB8/PSMB9/TAPBP/ITPR3/RUNX2/TPBG/NT5E/MOXD1/MICALL2/GPNMB/INHBA/SAMD9/SAMD9L/TRIP6/PARP12/GIMAP2/MSR1/CTHRC1/TNFRSF11B/COL14A1/DDX58/COL27A1/COL5A1/TOR4A/APBB1IP/ALOX5/SRGN/ZCCHC24/FAS/HTR7/MYOF/PTPRE/PGGHG/FIBIN/SLC15A3/MYRF/PLAAT4/EHBP1L1/SYTL2/BIRC3/CASP1/NNMT/TAGLN/C1S/C1R/ARHGDIB/BHLHE41/STAT6/LUM/DRAM1/NUAK1/SELPLG/SLC46A3/IRF9/TNFAIP2/CRIP1/FBN1/ANXA2/TPM1/LOXL1/BCL2A1/MFGE8/IL32/NLRC5/PSMB10/SLFN5/SLFN11/CCL5/COL1A1/MILR1/SOCS3/ALPK2/FXYD5/GMFG/AXL/EMP3/IL4I1/RAC2/ARHGEF6/GABRE | 109 |
| GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT | GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT | GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT | 62/1438 | 172/23056 | 0.3604651 | 5.779474 | 16.226790 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/TINAGL1/PODN/CCN1/ECM1/LAMC2/HMCN1/PRG4/PRELP/OPTC/LAMB3/NID1/LTBP1/EFEMP1/COL3A1/COL5A2/FN1/COL6A3/COL7A1/LAMB2/COL8A1/ENAM/NPNT/HAPLN1/EDIL3/TGFBI/SPARC/COL21A1/COL19A1/COL12A1/LAMA4/LAMA2/THBS2/MATN2/CTHRC1/COL14A1/COL27A1/COL5A1/COL13A1/MMRN2/TECTB/EFEMP2/VWF/LUM/POSTN/NID2/LTBP2/FBLN5/THBS1/FBN1/MFGE8/COL1A1/EMILIN2/COL9A3/COL18A1/COL6A2/MXRA5/SRPX2/COL4A6/COL4A5/BGN | 62 |
| LIU_PROSTATE_CANCER_DN | LIU_PROSTATE_CANCER_DN | LIU_PROSTATE_CANCER_DN | 107/1438 | 491/23056 | 0.2179226 | 3.494036 | 14.407215 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/HSPG2/TMEM200B/PODN/NEXN/GBP2/CRABP2/PRRX1/MR1/LMOD1/PRELP/ATP2B4/LAMB3/TGFB2/NID1/SRD5A2/LTBP1/CRIM1/EFEMP1/ACTG2/CAPG/VAMP5/GYPC/ITGB6/DES/ACKR3/COL7A1/LAMB2/UBA7/PRICKLE2/MYLK/MME/PDGFC/ITGA2/TSLP/PPIC/SPARC/GALNT10/ID4/HLA-E/RCAN2/LAMA4/GJA1/PDK4/TRIP6/CAV2/CAV1/MET/FLNC/RARRES2/CLU/RBPMS/PLEKHA2/COL14A1/AQP3/TPM2/COL27A1/COL5A1/ITGA8/COL13A1/PLAU/VCL/MYOF/FGFR2/EHF/EFEMP2/PRSS23/PGR/CASP1/LAYN/CRYAB/TAGLN/MPZL2/C1S/C1R/KRT7/MSRB3/TRPC4/AJUBA/FRMD6/FBLN5/AHNAK2/FBN1/ANXA2/TPM1/CRISPLD2/FOXF1/MYOCD/SLC47A1/SLFN5/KRT13/KRT15/KRT19/KRT17/CAVIN1/ABCC3/MRC2/C1QTNF1/SLC14A1/EHD2/ADAM33/MYL9/ADAMTS5/CLIC6/LGALS1/COL4A6/GABRE | 107 |
| GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION | 101/1438 | 446/23056 | 0.2264574 | 3.630877 | 14.470116 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/RUNX3/CCN1/VCAM1/CSF1/PTPN22/S100A10/TNFSF18/PTPRC/TGFB2/ITPKB/NID1/NLRP3/VIT/IL1A/IL1B/DPP4/ITGA4/FN1/EPHA4/TGFBR2/WNT5A/COL8A1/CCDC80/BCL6/HES1/KDR/NPNT/LEF1/IL15/MYO10/IL7R/DAB2/ITGA2/EDIL3/ADAM19/RREB1/HLA-E/VNN1/CITED2/UTRN/IL6/GLI3/CD36/COL26A1/CAV1/PODXL/SHH/PLEKHA2/ADAM9/ANGPT1/HAS2/CD274/PDCD1LG2/TEK/ANXA1/APBB1IP/MAP3K8/NRP1/ALOX5/SAA1/CD44/PTPRJ/EFEMP2/APOA1/KLRC4-KLRK1/ITGA5/NCKAP1L/TESPA1/IGF1/TNFSF13B/TPM1/IL4R/CDH13/FOXF1/PIEZO1/CCL5/CCR7/JUP/ITGA3/EMILIN2/FSTL3/ELANE/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/RRAS/IL4I1/SIRPG/SIRPA/RIN2/TGM2/SDC4/RUNX1/ICOSLG/LIF/LGALS1/PDGFB | 101 |
| HALLMARK_INFLAMMATORY_RESPONSE | HALLMARK_INFLAMMATORY_RESPONSE | HALLMARK_INFLAMMATORY_RESPONSE | 66/1438 | 200/23056 | 0.3300000 | 5.291015 | 15.719155 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/TNFRSF1B/CSF1/NLRP3/IL1R1/IL1A/IL1B/NMI/IRAK2/HRH1/STAB1/RTP4/SLC4A4/CXCL8/CXCL6/EREG/SGMS2/IL15/TLR3/IL7R/OSMR/HBEGF/EDN1/RNF144B/TAPBP/TPBG/ROS1/AHR/ITGB8/IL6/INHBA/SERPINE1/MET/MSR1/HAS2/TNFSF15/IL15RA/PTPRE/ADM/CD82/P2RY2/C3AR1/ITGA5/MMP14/NFKBIA/BDKRB1/GPR132/IL4R/CCL5/CSF3/CCR7/KCNJ2/EBI3/TNFSF9/CD70/ADGRE1/ICAM1/SCN1B/AXL/C5AR1/EMP3/FPR1/ICOSLG/LIF/IL2RB/NDP | 66 |
| ROZANOV_MMP14_TARGETS_UP | ROZANOV_MMP14_TARGETS_UP | ROZANOV_MMP14_TARGETS_UP | 76/1438 | 267/23056 | 0.2846442 | 4.563809 | 15.106422 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/TMCO4/FUCA1/GBP3/S100A2/HSD11B1/EFEMP1/IL1R1/LYPD6B/FN1/PPARG/CDCP1/MYLK/HEG1/SLCO2A1/SOD3/PLAC8/TDO2/TRIML2/NKD2/SLC12A7/FST/PLK2/LAMA4/CCN2/PDGFRL/MATN2/TNFRSF11B/HAS2/PTGR1/PTGS1/COL5A1/PAEP/ANKRD1/PYROXD2/IFITM2/MYRF/PLAAT4/PLAAT3/EFEMP2/SERPINH1/NNMT/TAGLN/SCNN1A/AMIGO2/DNAJC22/GLIPR1/RAB20/MMP14/FRMD6/CGNL1/TPM1/CA12/RBPMS2/UACA/CSPG4/IL32/NUPR1/COLEC12/EMILIN2/MOCOS/ALPK2/ADGRE1/GMFG/IL4I1/CACNG6/SIRPA/CRLS1/RIN2/MX1/COL18A1/COL6A2/APOL3/IL2RB/ITM2A/SRPX2 | 76 |
| MEBARKI_HCC_PROGENITOR_WNT_UP | MEBARKI_HCC_PROGENITOR_WNT_UP | MEBARKI_HCC_PROGENITOR_WNT_UP | 65/1438 | 200/23056 | 0.3250000 | 5.210848 | 15.425482 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/SPOCD1/CCN1/GBP1/PTPN22/OLFML3/TCHH/HMCN1/TGFB2/IL1R1/LYPD1/FAP/COL3A1/COL5A2/FN1/CDCP1/TMEM158/PRICKLE2/CCDC80/SLC12A8/LRRC15/STK32B/CXCL3/LEF1/NKD2/HAPLN1/TGFBI/SPARC/ADAM19/RBM24/MDFI/RSPO3/MOXD1/THBS2/SEMA3C/SERPINE1/PDGFRL/TRIM55/CTHRC1/EXT1/PCSK5/FIBCD1/CLIC3/PAMR1/PRSS23/LAYN/ARHGDIB/ITGA5/GLIPR1/EPYC/LUM/LCP1/DACT1/BMF/FBN1/MMP2/CRISPLD2/COL1A1/NOG/MRC2/MILR1/ITGB4/MYH9/KLHL4/SRPX2 | 65 |
| PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | 66/1438 | 210/23056 | 0.3142857 | 5.039062 | 15.164893 | 0.0000000 | 0.0000000 | 0.0000000 | HSPG2/FUCA1/NEXN/VCAM1/PRRX1/CFH/CYP26B1/HNMT/CYBRD1/COL3A1/FN1/CCDC80/FSTL1/MYLK/WWTR1/PLD1/FAM114A1/TDO2/GASK1B/RAI14/OSMR/DAB2/PPIC/SPARC/ADGRF5/COL12A1/LAMA4/GJA1/RSPO3/GPNMB/TNS3/SAMD9L/CAV2/RARRES2/CLU/RBPMS/TCIM/SULF1/CTHRC1/CCN4/S1PR3/PAPSS2/SLCO2B1/SERPINH1/ARHGAP42/YAP1/NNMT/TAGLN/VWF/C1S/C1R/LUM/FBN1/TPM1/LOXL1/ITPRIPL2/CETP/CAVIN1/COL1A1/ABCC3/C3/APOE/PLA2G4C/RRAS/MYL9/MXRA5 | 66 |
| JOHNSTONE_PARVB_TARGETS_3_UP | JOHNSTONE_PARVB_TARGETS_3_UP | JOHNSTONE_PARVB_TARGETS_3_UP | 97/1438 | 433/23056 | 0.2240185 | 3.591773 | 14.041714 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/ERRFI1/ECE1/CSF1/CTSS/S100A2/S100A16/ATP2B4/SULT1C2/HNMT/CDK15/FN1/BHLHE40/IRAK2/TGFBR2/VIPR1/CDCP1/PLD1/RBM47/ABCG2/OSMR/ITGA2/TGFBI/CCDC69/GFPT2/DSP/HLA-E/PSMB9/TAPBP/PTP4A1/CITED2/PDK4/MDFIC/PARP12/LOXL2/CLU/ZNF703/CEBPD/ST3GAL1/AQP3/ANXA1/KLF4/PTGR1/GSN/CLIC3/AKR1C3/PLAU/MYOF/LOXL4/DNMBP/ACSL5/HTRA1/PTPRE/IFITM3/MICAL2/AHNAK/PLAAT3/ALDH3B1/BCL9L/SCNN1A/C1S/H2AJ/KRT80/STAT6/NFKBIA/PYGL/TNFAIP2/AHNAK2/THBS1/CA12/UACA/ORAI3/NLRC5/CRISPLD2/PITPNM3/KRT19/JUP/IFI35/ABCC3/ITGB4/TMC8/LIPG/C3/ICAM1/FXYD5/BCL3/EHD2/PRNP/THBD/TGM2/CEBPB/COL18A1/LIF/HMOX1/APOL6/MYH9/CELSR1 | 97 |
| SANA_TNF_SIGNALING_UP | SANA_TNF_SIGNALING_UP | SANA_TNF_SIGNALING_UP | 42/1438 | 83/23056 | 0.5060241 | 8.113276 | 16.743804 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP1/VCAM1/CSF1/LAMB3/ACKR3/PARP14/CXCL8/CXCL6/CXCL3/CXCL2/DDX60/IL7R/HLA-E/HLA-C/TAPBP/TNFAIP3/SOD2/INHBA/SAMD9L/SERPINE1/PDGFRL/CTHRC1/SLC15A3/BIRC3/MMP10/MMP3/CASP1/C1S/DRAM1/NFKBIA/TNFAIP2/IL32/C1QTNF1/LIPG/ICAM1/MX2/MX1/ICOSLG/APOL3/APOL1/SAT1 | 42 |
| MCLACHLAN_DENTAL_CARIES_UP | MCLACHLAN_DENTAL_CARIES_UP | MCLACHLAN_DENTAL_CARIES_UP | 73/1438 | 265/23056 | 0.2754717 | 4.416742 | 14.428053 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/VCAM1/CD53/CTSS/FCGR2A/PTGS2/PTPRC/CAPG/IL1B/KYNU/SERPINE2/STAB1/LRRC15/SEL1L3/JCHAIN/CXCL8/CXCL1/CXCL5/PLAC8/SPP1/CFI/SLC7A11/IL7R/MZB1/IER3/PLA2G7/TNFRSF21/CRYBG1/TNFAIP3/SOD2/IL6/GPNMB/SKAP2/INHBA/MSR1/CEBPD/AQP3/ALOX5/SRGN/PLAU/ADM/SAA1/CD44/MS4A4A/BIRC3/MMP1/NNMT/C3AR1/ARHGDIB/SLC46A3/ALOX5AP/LCP1/SERPINA1/CA12/BCL2A1/ANPEP/MT2A/MT1X/CCL5/PECAM1/SOCS3/SERPINB2/C3/ICAM1/BCL3/APOE/C5AR1/CD37/FPR1/IL11/RAC2/SAT1/IL13RA1 | 73 |
| ONDER_CDH1_TARGETS_2_UP | ONDER_CDH1_TARGETS_2_UP | ONDER_CDH1_TARGETS_2_UP | 71/1438 | 257/23056 | 0.2762646 | 4.429455 | 14.258966 | 0.0000000 | 0.0000000 | 0.0000000 | OLFML3/ITGA10/PRRX1/NID1/LTBP1/GYPC/CYBRD1/TFPI/COL3A1/COL5A2/AOX1/FN1/ACKR3/COL6A3/MLPH/IL17RC/PPARG/WNT5A/MITF/COL8A1/MME/FAT4/SEMA5A/DAB2/ABLIM3/SPARC/GALNT10/PXDC1/RCAN2/CCN2/MOXD1/CITED2/SERPINE1/PODXL/PDGFRL/MYBL1/TRPA1/HAS2/KLF4/COL5A1/NRP1/SRGN/ZCCHC24/PPP1R3C/MICAL2/CREB3L1/PLAAT3/NNMT/TAGLN/EPS8/ITGA7/PPM1H/SLC46A3/POSTN/NID2/LTBP2/FBLN5/FBN1/TPM1/ANPEP/NUPR1/MMP2/COL1A1/WIPI1/ABCA8/GADD45B/MYL9/COL6A2/HMOX1/KDELR3/BGN | 71 |
| PASINI_SUZ12_TARGETS_DN | PASINI_SUZ12_TARGETS_DN | PASINI_SUZ12_TARGETS_DN | 79/1438 | 316/23056 | 0.2500000 | 4.008345 | 13.887696 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/SPSB1/CCN1/GBP2/CSF1/S100A10/TGFB2/EFEMP1/COL3A1/FN1/BHLHE40/VGLL3/PHLDB2/AMOTL2/WWTR1/LPP/ANXA3/NPNT/PLK2/HBEGF/DSP/IER3/NT5E/PERP/CITED2/GLI3/SEMA3C/CAV2/CAV1/FLNC/ZYX/LOXL2/SULF1/CA3/LRATD2/CCN4/TPM2/ANXA1/GSN/AIF1L/COL5A1/SYNPO2L/VCL/AHNAK/SERPINH1/PRSS23/CRYAB/TAGLN/GPRC5A/KRT8/KRT18/HMGA2/PHLDA1/TMCC3/NUAK1/TNFRSF19/MMP14/BMP4/ACTC1/THBS1/ANXA2/TPM1/TNFRSF12A/KRT19/CAVIN1/ITGA3/COL1A1/METRNL/COLEC12/CNN2/CNN1/AXL/PRNP/BMP2/LGALS1/PDGFB/MSN/LPAR4/COL4A5 | 79 |
| GOBP_CELL_SUBSTRATE_ADHESION | GOBP_CELL_SUBSTRATE_ADHESION | GOBP_CELL_SUBSTRATE_ADHESION | 85/1438 | 365/23056 | 0.2328767 | 3.733801 | 13.578154 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/GBP1/VCAM1/CSF1/ITGA10/S100A10/CD34/LAMB3/NID1/VIT/ITGB6/ITGA6/ITGA4/COL3A1/FN1/LAMB2/EPHA3/COL8A1/CD96/PHLDB2/CCDC80/ITGB5/BCL6/KDR/NPNT/ADAMTS12/DAB2/ITGA2/EDIL3/RREB1/DDR1/PTPRK/CCN2/UTRN/MICALL2/ITGB8/HOXA7/CD36/TRIP6/SERPINE1/COL26A1/ZYX/PLEKHA2/ADAM9/ANGPT1/HAS2/TEK/NOTCH1/ITGA8/NRP1/COL13A1/PLAU/VCL/CD44/PTPRJ/EFEMP2/FZD4/APOA1/VWF/ITGA5/ITGA7/MMP14/AJUBA/NID2/FBLN5/THBS1/SMAD6/ITGA11/MSLN/MSLNL/CDH13/FOXF1/CCR7/JUP/ITGA3/COL1A1/ITGB4/AXL/LYPD3/BCAM/RRAS/RIN2/SDC4/RAC2/PDGFB | 85 |
| GOBP_WOUND_HEALING | GOBP_WOUND_HEALING | GOBP_WOUND_HEALING | 93/1438 | 431/23056 | 0.2157773 | 3.459639 | 13.294436 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/RHOC/PLA2G4A/CD34/TGFB2/TGFA/IL1A/ITGB6/FAP/TFPI/COL3A1/FN1/SERPINE2/PPARG/TGFBR2/WNT5A/PHLDB2/MYLK/CLDN1/TXK/TEC/KDR/EREG/ARHGAP24/SLC7A11/ITGA2/F2RL1/HBEGF/RREB1/DSP/ADTRP/EDN1/DDR1/TREML1/CD109/TNFAIP3/PDGFA/IL6/GLI3/CD36/SERPINE1/CAV1/SHH/PLAT/FZD6/EXT1/CCN4/EPPK1/B4GALT1/ANXA1/COL5A1/ALOX5/ANXA8/MYOZ1/PLAU/VCL/PAPSS2/MYOF/FGFR2/NLRP6/TSPAN32/SAA1/CD44/YAP1/UBASH3B/VWF/ITGA5/IGF1/LCP1/AJUBA/SERPINA10/SERPINA1/THBS1/TPM1/TNFRSF12A/ADAMTS18/COL1A1/NOG/C1QTNF1/EMILIN2/SERPINB2/CNN2/CYP4F11/AXL/TGFB1/APOE/THBD/PROCR/MYL9/SDC4/HMOX1/MYH9/PDGFB | 93 |
| PID_INTEGRIN1_PATHWAY | PID_INTEGRIN1_PATHWAY | PID_INTEGRIN1_PATHWAY | 36/1438 | 66/23056 | 0.5454545 | 8.745480 | 16.251934 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/ITGA10/LAMC2/LAMB3/NID1/ITGA6/ITGA4/COL3A1/COL5A2/FN1/COL6A3/COL7A1/LAMB2/SPP1/NPNT/ITGA2/TGFBI/LAMA4/LAMA2/THBS2/COL5A1/ITGA8/PLAU/ITGA5/ITGA7/THBS1/FBN1/ITGA11/CSPG4/ITGA3/COL1A1/TGM2/COL18A1/COL6A2/COL4A6/COL4A5 | 36 |
| HUANG_DASATINIB_SENSITIVITY_UP | HUANG_DASATINIB_SENSITIVITY_UP | HUANG_DASATINIB_SENSITIVITY_UP | 39/1438 | 80/23056 | 0.4875000 | 7.816273 | 15.751031 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/GBP3/IFI16/LAMB3/TFPI/TGFBR2/FSTL1/P3H2/PDGFC/MYO10/RAI14/OSMR/F2RL1/ELL2/TGFBI/PSMB8/PSMB9/TNFRSF21/SAMD9L/CAV2/CAV1/MET/ZYX/EXT1/ANXA1/COL5A1/AKR1C3/IL15RA/PLAU/MAML2/LAYN/NNMT/ITGA5/COTL1/CAVIN1/FXYD5/PRNP/RAC2/MSN | 39 |
| DURAND_STROMA_S_UP | DURAND_STROMA_S_UP | DURAND_STROMA_S_UP | 75/1438 | 300/23056 | 0.2500000 | 4.008345 | 13.526784 | 0.0000000 | 0.0000000 | 0.0000000 | MMP23B/S1PR1/S100A16/NIBAN1/CYP26B1/IL1R1/COL3A1/CCDC80/RTP4/CLDN1/SPON2/SLC4A4/SPP1/FAT4/IL15/INPP4B/CTSO/NPR3/ADAMTS12/OSMR/ELL2/TGFBI/ADAM19/ADAMTS2/SERPINB1/TFAP2A/UST/AHR/BMPER/FZD1/PDK4/MEST/PODXL/PTN/CSGALNACT1/PLEKHA2/FABP4/CA13/MATN2/RSPO2/ST3GAL1/PAPPA/FZD8/FGFR2/CREB3L1/UBASH3B/WNT10B/IGF1/OASL/POSTN/PRKD1/NID2/SIX1/LTBP2/RBPMS2/LOXL1/IL4R/MMP2/MAF/CDYL2/SLFN13/CCL5/JUP/HOXB13/COL1A1/SCN1B/COL6A2/MN1/A4GALT/LPAR4/ITM2A/SRPX2/COL4A6/IL13RA1/ARHGEF6 | 75 |
| ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | 65/1438 | 232/23056 | 0.2801724 | 4.492111 | 13.787654 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ZC3H12A/PTGS2/ELF3/IL1A/IL1B/DPP4/CAVIN2/BHLHE40/HRH1/VGLL3/PHLDB2/CLDN1/IL1RAP/HES1/CXCL8/CXCL1/CXCL2/PLAC8/SGMS2/ITGA2/PLK2/F2RL1/ELL2/HBEGF/EDN1/IER3/ADGRF4/PTP4A1/TNFAIP3/STX11/MAFK/MACC1/IL6/HOXA1/SEMA3C/SEMA3A/SERPINE1/CEBPD/LRATD2/IFNE/CEMIP2/KLF4/MAP3K8/MYPN/DNMBP/NFKB2/ITPRIP/ADM/PYGM/SYT12/ARHGAP42/BIRC3/EMP1/LATS2/FRMD6/ZFP36L1/FOS/SOCS3/METRNL/GATA6/MBP/BCL3/KLK6/RUNX1 | 65 |
| SEAVEY_EPITHELIOID_HEMANGIOENDOTHELIOMA | SEAVEY_EPITHELIOID_HEMANGIOENDOTHELIOMA | SEAVEY_EPITHELIOID_HEMANGIOENDOTHELIOMA | 41/1438 | 93/23056 | 0.4408602 | 7.068479 | 15.123812 | 0.0000000 | 0.0000000 | 0.0000000 | TINAGL1/NEXN/CCN1/TGFB2/LTBP1/EFEMP1/COL8A1/VEPH1/ANXA3/MYOZ2/ERAP2/BMP6/EDN1/MICB/TNFRSF21/HOXA1/SEMA3D/SERPINE1/PLAT/HRCT1/NXNL2/TNFSF15/ANKRD1/WT1/MSRB3/LATS2/BMP4/TNFRSF12A/MYLK3/CDH13/FOXF1/ITGA3/FSTL3/GDF15/WTIP/NPAS1/EHD2/CACNG6/CDC42EP5/BACE2/SRPX2 | 41 |
| SMID_BREAST_CANCER_NORMAL_LIKE_UP | SMID_BREAST_CANCER_NORMAL_LIKE_UP | SMID_BREAST_CANCER_NORMAL_LIKE_UP | 97/1438 | 484/23056 | 0.2004132 | 3.213301 | 12.692070 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/RUNX3/TIE1/VCAM1/PTPN22/IFI16/CFH/PTPRC/LMOD1/NLRP3/RASGRP3/EFEMP1/VAMP5/IL1R1/DPP4/ITGA4/TFPI/CASP10/DES/EPHA4/SP110/CD96/MYLK/MME/P3H2/SEL1L3/JCHAIN/CXCL2/PLAC8/LEF1/CFI/IL7R/SNCAIP/MZB1/CCDC69/DOCK2/ID4/ADGRF5/NT5E/LAMA4/LAMA2/VNN2/IL6/SKAP2/HOXA7/AQP1/CAV1/MET/PTN/CSGALNACT1/DOK2/ADAM28/CLU/PNOC/FABP4/MATN2/COL14A1/PCSK5/SRGN/HHEX/SAA1/BBOX1/BIRC3/CASP1/CRYAB/C1S/C1R/NCKAP1L/TESPA1/ITGA7/GLIPR1/IGF1/FBLN5/IL21R/LAT/CES1/COTL1/CCL5/CCR7/MEOX1/FMNL1/PECAM1/ABCA8/ABCA6/MBP/C3/CNN1/IL27RA/CD22/GMFG/CD37/THBD/COL18A1/RAC2/LGALS2/APOBEC3G/ITM2A | 97 |
| ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP | 63/1438 | 223/23056 | 0.2825112 | 4.529610 | 13.660036 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/SPSB1/ZC3H12A/GBP3/NUAK2/LAMB3/IL1A/IL1B/IL36G/KYNU/IRAK2/AMOTL2/TM4SF1/ARL14/CLDN1/CXCL8/CXCL1/CXCL3/CXCL2/IL15/IL7R/GRAMD2B/HBEGF/SERPINB1/EDN1/TRIM38/LAMA2/TNFAIP3/ITGB8/INHBA/TCIM/DDX58/TRAF1/PLAU/ANKRD22/NFKB2/ARHGAP42/BIRC3/MMP10/STYK1/NAV3/TMCC3/DRAM1/OASL/IRF9/NFKBIA/TNFAIP2/GPR132/BCL2A1/IL32/SLFN5/CCL5/SOCS3/ICAM1/LYPD3/BCL3/RELB/IL4I1/BMP2/SDC4/CEBPB/USP18/LIF | 63 |
| SENESE_HDAC1_AND_HDAC2_TARGETS_DN | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | 65/1438 | 238/23056 | 0.2731092 | 4.378864 | 13.513713 | 0.0000000 | 0.0000000 | 0.0000000 | EDN2/NEXN/OLFML3/TGFB2/LBH/TMEM37/TFPI/COL3A1/COL5A2/CAVIN2/ACKR3/LAMB2/SEMA3B/TNNC1/WNT5A/PRICKLE2/GXYLT2/CCDC80/FSTL1/MYLK/PLAC8/SPP1/EGF/HAPLN1/EDIL3/CAP2/GPNMB/AQP1/PDE1C/TNS3/CCL26/CAV1/PDGFRL/CLU/MYBL1/MATN2/NACC2/ALOX5/ANXA8/LOXL4/SYT12/ALDH3B1/SYTL2/CRYAB/TAGLN/KRT80/LUM/DACT1/TPM1/SMAD6/LOXL1/MSLN/NUPR1/MAF/KRT15/KRT17/COL1A1/ABCC3/NOG/WIPI1/ALPK2/MYL9/MN1/CSDC2/PLS3 | 65 |
| OISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN | OISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN | OISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN | 70/1438 | 274/23056 | 0.2554745 | 4.096119 | 13.296926 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CDA/ECE1/HSPG2/VCAM1/MTMR11/ECM1/NIBAN1/PTGS2/EFEMP1/ITGB6/FAP/COL3A1/COL5A2/NRP2/KCNE4/RARB/SULT1E1/PLAC8/VEGFC/CCDC69/ADAMTS2/SERPINB1/H1-3/CRYBG1/CCN2/MOXD1/CITED2/STX11/THBS2/AHR/SEMA3A/TPK1/MSC/ZFPM2/TPM2/GAS1/COL5A1/CLIC3/ALOX5/DKK1/PAPSS2/ACSL5/CD82/CREB3L1/EFEMP2/LRRC32/SYTL2/TAGLN/GPRC5A/EMP1/MMP14/ZFP36L1/FBN1/MT2A/MT1X/TRPV2/SGCA/GATA6/CNN2/KCNN4/EMP3/RRAS/RIN2/PROCR/MYL9/PTGIS/MX2/COL6A2/BGN | 70 |
| GHANDHI_DIRECT_IRRADIATION_UP | GHANDHI_DIRECT_IRRADIATION_UP | GHANDHI_DIRECT_IRRADIATION_UP | 43/1438 | 105/23056 | 0.4095238 | 6.566051 | 14.743319 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/PTGS2/LAMB3/HSD11B1/CYP26B1/IL1A/IL1B/KYNU/CLDN1/CXCL8/CXCL1/CXCL5/CXCL3/CXCL2/SLC7A11/GDNF/TSLP/TNFAIP3/SOD2/IL6/INHBA/TNFRSF10C/TCIM/MYBL1/IFNE/DKK1/MYPN/FAS/PTPRE/BIRC3/MMP10/MMP1/MMP3/PLEK2/BCL2A1/MT2A/MT1X/SERPINB2/GDF15/RELB/IL11/BMP2/LIF | 43 |
| SWEET_LUNG_CANCER_KRAS_DN | SWEET_LUNG_CANCER_KRAS_DN | SWEET_LUNG_CANCER_KRAS_DN | 89/1438 | 423/23056 | 0.2104019 | 3.373453 | 12.706738 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/CCN1/GBP2/GBP4/FMO3/CFH/HSD11B1/ITPKB/NID1/IL1B/TFPI/COL3A1/CAVIN2/ACKR3/ACKR2/TNNC1/STAB1/WWTR1/SOD3/KDR/NPNT/NPR3/ADRB2/SPARC/BMP6/EDN1/LAMA2/SASH1/AHR/AQP1/MYL7/UPK3B/SEMA3C/CAV1/RARRES2/CA3/ANGPT1/ADCY8/TMEM71/TEK/KLF4/GSN/SRGN/COL13A1/VCL/PLAC9/PAPSS2/FAS/ANKRD1/IFITM3/HBD/MS4A4A/AHNAK/TAGLN/VWF/KRT4/TNS2/IGFBP6/LATS2/TNFRSF19/FLT1/POSTN/EDNRB/SLC10A2/NFKBIA/CRIP1/ACTC1/SMAD6/LOXL1/BNC1/MSLN/CES1/PSMB10/FOXF1/MYH1/KRT13/CAVIN1/MYL4/COL1A1/GADD45B/C3/IL27RA/KLF2/GMFG/THBD/MYL9/PTGIS/COL6A2/USP18 | 89 |
| KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | 78/1438 | 336/23056 | 0.2321429 | 3.722035 | 12.963234 | 0.0000000 | 0.0000000 | 0.0000000 | ECE1/CCN1/C1orf54/S100A10/HMCN1/TGFB2/CYP26B1/RPRM/DLX1/DLX2/TFPI/COL3A1/COL5A2/FN1/TGFBR2/COL7A1/LAMB2/EPHA3/CCDC80/FSTL1/AMOTL2/FNDC3B/HES1/C9/DAB2/CARD6/SPARC/FOXC1/PXDC1/TRIM38/HLA-E/IER3/TENT5A/NT5E/LAMA4/GPNMB/FZD1/ZYX/SLC26A7/ANGPT1/GSN/COL5A1/AKR1C3/DKK1/PLAU/VCL/ZCCHC24/PAPSS2/TCF7L2/ADM/CREB3L1/PRSS23/TAGLN/BCL9L/AMIGO2/NUAK1/POSTN/FOXO1/LRP10/AJUBA/FRMD6/FBN1/SMAD6/ORAI3/SLFN5/HOXB13/COL1A1/METRNL/COLEC12/MYOM1/KLF2/PRND/RIN2/DOK5/ADAMTS5/MLC1/SAT1/IL13RA1 | 78 |
| GOBP_UROGENITAL_SYSTEM_DEVELOPMENT | GOBP_UROGENITAL_SYSTEM_DEVELOPMENT | GOBP_UROGENITAL_SYSTEM_DEVELOPMENT | 80/1438 | 353/23056 | 0.2266289 | 3.633627 | 12.860394 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/TGFB2/AGT/NID1/OSR1/BMP10/CYP26B1/EPHA4/RARB/LAMB2/WNT5A/WWTR1/MME/HES1/SLIT2/NPNT/IRX2/ADAMTS16/GDNF/ADAMTS6/FOXD1/FOXC1/BMP6/TFAP2A/ID4/TBX18/SIM1/PDGFA/BMPER/GLI3/PODXL/SHH/PLAG1/SULF1/GDF6/ANGPT1/EXT1/HAS2/TEK/ANXA1/PCSK5/NOTCH1/ITGA8/NRP1/CYP26A1/FGFR2/WT1/YAP1/TNS2/GLI1/FREM2/EDNRB/BMP4/SIX1/SIX4/CRIP1/FBN1/CYP19A1/ALDH1A2/MYO1E/FOXB1/SMAD6/SOX8/SALL1/MMP2/FOXF1/MYOCD/LHX1/HOXB7/HOXB13/ITGA3/NOG/PECAM1/SOX9/SERPINB7/BMP2/SDC4/LIF/PDGFB/WNT7B | 80 |
| RIGGI_EWING_SARCOMA_PROGENITOR_UP | RIGGI_EWING_SARCOMA_PROGENITOR_UP | RIGGI_EWING_SARCOMA_PROGENITOR_UP | 90/1438 | 434/23056 | 0.2073733 | 3.324894 | 12.610632 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/PTPN22/OLFML3/HMCN1/PTGS2/PRELP/LAMB3/LBH/TGFA/CYP26B1/TMEM37/LYPD1/GALNT3/ITGA4/EPHA4/KCNE4/EPHA3/CLDN1/IL1RAP/HES1/STK32B/SLIT2/SEL1L3/ADAMTS3/CDS1/SPP1/LEF1/FAT4/TDO2/MYO10/NPR3/STING1/HBEGF/FGF18/RBM24/ID4/HLA-E/COL21A1/TRDN/CITED2/PDGFA/SCIN/CD36/FZD1/CADPS2/GPR37/PODXL/AKR1B10/RARRES2/GIMAP2/EBF2/PNOC/ZNF703/FABP4/LRATD2/CD274/AQP3/S1PR3/TNFSF15/CLIC3/JCAD/FZD8/ANKRD1/WT1/FZD4/MMP1/CASP1/CARD16/CRYAB/OPCML/C3AR1/ARHGDIB/BHLHE41/IGF1/LRFN5/FOS/CRIP1/PAQR5/CES1/SLFN11/SLFN12/KRT17/SIGLEC15/ICAM1/GDF15/TGFB1/PLA2G4C/ITM2A/IL13RA1/ARHGEF6 | 90 |
| GOBP_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | GOBP_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | GOBP_CYTOKINE_MEDIATED_SIGNALING_PATHWAY | 96/1438 | 485/23056 | 0.1979381 | 3.173617 | 12.477651 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/TNFRSF4/TNFRSF1B/IL22RA1/EDN2/GFI1/CSF1/ECM1/TNFSF18/PTPRC/IKBKE/IL1R1/IL1A/IL1B/IL36G/NMI/CASP8/SP100/ACKR3/IL17RC/IRAK2/PPARG/ACKR2/CCR3/WNT5A/PARP14/IL1RAP/SLIT2/TXK/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EREG/IL15/IL7R/OSMR/IL31RA/F2RL1/TSLP/CSF2/STING1/FOXC1/EDN1/TNFAIP3/IL6/CCL26/TRIM56/CAV1/ANGPT1/EXT1/IFNE/TRAF1/NOTCH1/IL15RA/FAS/IFITM2/IFITM3/CD44/PTPRJ/FZD4/YAP1/BIRC3/CASP4/CASP1/CARD16/APOA1/TNFRSF1A/KRT18/STAT6/OASL/TNFRSF19/FLT3/TNFSF13B/NFKBIA/IL4R/IL21R/NLRC5/CCL5/CSF3/CCR7/TNFRSF11A/EBI3/CD70/IL27RA/PLVAP/IL12RB1/AXL/BIRC7/MX1/USP18/IL2RB/PDGFB/IL13RA1 | 96 |
| GOMF_GLYCOSAMINOGLYCAN_BINDING | GOMF_GLYCOSAMINOGLYCAN_BINDING | GOMF_GLYCOSAMINOGLYCAN_BINDING | 64/1438 | 236/23056 | 0.2711864 | 4.348035 | 13.333447 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/CCN1/LAMC2/CFH/PTPRC/LGR6/PRELP/NLRP3/VIT/NRP2/FN1/SERPINE2/TGFBR2/SUSD5/STAB1/CCDC80/FSTL1/FGFRL1/SLIT2/SOD3/JCHAIN/ADAMTS3/CXCL8/CXCL6/SEMA5A/HAPLN1/HBEGF/RSPO3/CCN2/THBS2/TMEM184A/GPNMB/PTN/SHH/SULF1/RSPO2/CCN4/COL5A1/NRP1/COL13A1/FGFR2/SAA1/CD44/EFEMP2/LAYN/ADAMTS8/ADAMTS15/EPYC/POSTN/BMP4/LTBP2/SERPINA10/THBS1/FBN1/HAPLN3/CRISPLD2/LIPG/ELANE/ADAMTSL5/APOE/PRNP/ADAMTS5/TENM1/BGN | 64 |
| DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 67/1438 | 258/23056 | 0.2596899 | 4.163707 | 13.179897 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/ECM1/S100A10/S100A13/KCNN3/PRRX1/ITPKB/NID1/LTBP1/CYBRD1/NRP2/SERPINE2/ACKR3/EPHA3/HEG1/MME/P3H2/HES1/STK32B/PDGFC/VEGFC/FST/GALNT10/ADAM19/TPBG/TNFAIP3/INHBA/TNS3/FZD1/CAV2/CAV1/MET/LOXL2/PLAT/SULF1/COL14A1/AQP3/PCSK5/GAS1/KLF4/PTGS1/COL5A1/DKK1/PLAU/MYOF/TCF7L2/PTPRE/CD44/NNMT/VWA5A/EMP1/KRT18/IGFBP6/FOXO1/BMP4/THBS1/IL4R/IL27RA/FXYD5/SDC4/ADAMTS5/COL18A1/COL6A2/MN1/MYH9/CARD10/MSN | 67 |
| SEKI_INFLAMMATORY_RESPONSE_LPS_UP | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | SEKI_INFLAMMATORY_RESPONSE_LPS_UP | 37/1438 | 78/23056 | 0.4743590 | 7.605577 | 15.071492 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/GBP2/GBP4/VCAM1/CSF1/PRRX1/CXCL6/CXCL1/CXCL3/EREG/OSMR/PLK2/TSLP/IER3/TNFAIP3/STX11/SOD2/TCIM/CEMIP2/FAS/NFKB2/PTPRE/CD44/SLC15A3/FOSL1/BIRC3/CASP4/RND1/RAB20/NFKBIA/EXOC3L4/TNFAIP2/GADD45B/ICAM1/BMP2/ICOSLG/LIF | 37 |
| HAN_SATB1_TARGETS_DN | HAN_SATB1_TARGETS_DN | HAN_SATB1_TARGETS_DN | 84/1438 | 388/23056 | 0.2164948 | 3.471144 | 12.660812 | 0.0000000 | 0.0000000 | 0.0000000 | FUCA1/GBP2/ITGA10/S100A2/CRABP2/LAMC2/LAMB3/TGFB2/EFEMP1/NPAS2/SULT1C2/IL1B/ITGA6/MPP4/FN1/BHLHE40/TMEM158/CD96/CXCL1/FGF5/CDS1/LEF1/MYO10/IL7R/OSMR/TGFBI/SH3TC2/CCDC69/PXDC1/ID4/PSMB9/RUNX2/RCAN2/TENT5A/CCN2/ADGRG6/SYNJ2/FAM20C/IL6/INHBA/CCL26/SERPINE1/PTN/TPK1/CLU/TCIM/PLAT/CEBPD/MATN2/AQP3/TNFSF15/GSN/PAEP/AKR1C3/NRP1/PLAU/TCF7L2/SLC22A18/MMP10/MMP3/CASP1/MPZL2/EMP1/HMGA2/CA12/SMAD6/IL32/CLDN7/TRPV2/JUP/ITGA3/ACSF2/SLC16A5/ITGB4/GATA6/ADGRE1/GMFG/TGFB1/KCNN4/IL11/COL6A2/LIF/SAT1/ITM2A | 84 |
| PHONG_TNF_RESPONSE_NOT_VIA_P38 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | 78/1438 | 341/23056 | 0.2287390 | 3.667459 | 12.798907 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/TNFRSF1B/EPHA2/ECE1/GBP1/GBP2/VCAM1/CSF1/LAMC2/NIBAN1/IKBKE/NMI/NRP2/SP100/BHLHE40/PPARG/VIPR1/CDCP1/TMEM158/AMOTL2/CLDN1/HES1/TMEM156/RBM47/ARSJ/INPP4B/RAI14/ITGA2/CSF2/ABLIM3/GFPT2/PSMB9/MDFI/TNFRSF21/CRYBG1/SOD2/SERPINE1/PARP12/LOXL2/MYBL1/TRAF1/SRGN/PLAU/DNMBP/NFKB2/TCF7L2/PHLDA2/PRSS23/BIRC3/MMP1/GPRC5A/EMP1/BHLHE41/DRAM1/TPCN1/NFKBIA/TNFAIP2/CA12/BCL2A1/LAT/MMP2/FOXF1/SOX9/GPRC5C/RHBDF2/C1QTNF1/GATA6/FSTL3/CD70/ICAM1/BCL3/RELB/SDC4/CEBPB/COL6A2/MYH9/RAC2/MID1 | 78 |
| GOBP_CONNECTIVE_TISSUE_DEVELOPMENT | GOBP_CONNECTIVE_TISSUE_DEVELOPMENT | GOBP_CONNECTIVE_TISSUE_DEVELOPMENT | 67/1438 | 261/23056 | 0.2567050 | 4.115848 | 13.056628 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/CCN1/CSF1/ECM1/PRRX1/CD34/WNT9A/OSR1/EFEMP1/BMP10/DLX2/COL3A1/RARB/TGFBR2/WNT5A/FGFR3/NKX3-2/BMP3/ADAMTS12/FOXD1/TGFBI/FGF18/BMP6/EDN1/ID4/RUNX2/CCN2/PDGFA/SCIN/ITGB8/HOXA3/GLI3/CSGALNACT1/LOXL2/STC1/EBF2/SULF1/GDF6/RSPO2/TRPS1/EXT1/CCN4/COL27A1/COL5A1/NOTCH1/WT1/CD44/PLAAT3/SERPINH1/WNT10B/HMGA2/EPYC/BMP4/CRIP1/SOX8/MAF/HOXB3/COL1A1/NOG/SOX9/SERPINB7/TGFB1/BMP2/RUNX1/PDGFB/WNT7B/BGN | 67 |
| REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | 38/1438 | 85/23056 | 0.4470588 | 7.167864 | 14.692934 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/VCAM1/ITGA10/ITGB6/ITGA6/ITGA4/COL3A1/COL5A2/FN1/COL6A3/COL7A1/COL8A1/ITGB5/KDR/SPP1/ITGA2/ITGB8/COL5A1/ITGA8/COL13A1/CD44/VWF/ITGA5/ITGA7/LUM/THBS1/FBN1/ITGA11/ITGA3/COL1A1/PECAM1/ICAM1/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 38 |
| GOCC_ENDOPLASMIC_RETICULUM_LUMEN | GOCC_ENDOPLASMIC_RETICULUM_LUMEN | GOCC_ENDOPLASMIC_RETICULUM_LUMEN | 73/1438 | 310/23056 | 0.2354839 | 3.775602 | 12.689363 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/CSF1/ADAMTSL4/CASQ1/PTGS2/LTBP1/EVA1A/COL3A1/COL5A2/FN1/COL6A3/SHISA5/COL7A1/LAMB2/WNT5A/COL8A1/FSTL1/P3H2/AMTN/ENAM/SPP1/ARSJ/PDGFC/ERAP2/MZB1/ARSI/EDN1/COL21A1/COL19A1/COL12A1/TRDN/FUCA2/FAM20C/PDGFA/IL6/COL26A1/SHH/CLU/COL14A1/COL27A1/COL5A1/TOR4A/COL13A1/P4HA3/SERPINH1/PRSS23/APOA1/FLT3/BMP4/SERPINA10/SERPINA1/THBS1/FBN1/MFGE8/MSLN/CES1/GIP/COL1A1/FSTL3/EBI3/C3/APOE/COL9A3/ADAMTS5/COL18A1/COL6A2/APOL1/LGALS1/PDGFB/WNT7B/ARSL/COL4A6/COL4A5 | 73 |
| XIE_ST_HSC_S1PR3_OE_UP | XIE_ST_HSC_S1PR3_OE_UP | XIE_ST_HSC_S1PR3_OE_UP | 55/1438 | 188/23056 | 0.2925532 | 4.690616 | 13.104426 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/IFI44L/GBP1/GBP2/GBP5/TNFSF18/HMCN1/LAX1/SP110/COL6A3/IRAK2/XIRP1/CDCP1/SHISA5/SUCNR1/RTP4/CLDN16/KDR/SPP1/DDX60/DDX60L/DAB2/HBEGF/MOXD1/SAMD9/SAMD9L/SERPINE1/CAV2/PARP12/PARP10/DDX58/GSN/VCL/IFITM3/UBASH3B/VWA5A/KRT79/OASL/SLC7A7/IRF9/BMF/SMAD6/BCL2A1/SLFN5/CCL5/DHX58/IFI35/ABCC3/GPRC5C/RELB/MYL9/MX2/MX1/USP18/IL2RB | 55 |
| KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION | 66/1438 | 265/23056 | 0.2490566 | 3.993219 | 12.639620 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/TNFRSF4/TNFRSF9/TNFRSF1B/IL22RA1/CSF1/TNFSF18/TGFB2/IL1R1/IL1A/IL1B/TGFBR2/CCR3/IL1RAP/KDR/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EGF/IL15/PDGFC/VEGFC/IL7R/OSMR/TSLP/CSF2/TNFRSF21/PDGFA/IL6/INHBA/CCL26/MET/TNFRSF10C/TNFRSF10A/TNFRSF11B/IFNE/TNFSF15/IL15RA/FAS/TNFRSF1A/TNFRSF19/FLT3/FLT1/TNFSF13B/TNFRSF12A/IL4R/IL21R/CTF1/CCL5/CSF3/CCR7/TNFRSF11A/TNFSF9/CD70/TNFSF14/IL12RB1/TGFB1/IL11/BMP2/LIF/IL2RB/PDGFB/IL13RA1 | 66 |
| RODWELL_AGING_KIDNEY_NO_BLOOD_UP | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | 60/1438 | 223/23056 | 0.2690583 | 4.313914 | 12.825267 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/ITGB6/TFPI/COL3A1/FN1/SERPINE2/COL6A3/STAB1/MGLL/TM4SF18/CLDN1/CXCL6/CXCL2/PDGFC/VEGFC/OSMR/PLK2/ITPR3/TPBG/TMEM200A/MOXD1/MICALL2/GPNMB/INHBA/MSR1/CTHRC1/TNFRSF11B/COL14A1/ANXA1/COL27A1/COL5A1/ZCCHC24/MYOF/PGGHG/FIBIN/MYRF/SERPINH1/SYTL2/NNMT/TAGLN/C1S/C1R/BHLHE41/LUM/DRAM1/NUAK1/SLC46A3/FBN1/ANXA2/TPM1/LOXL1/MFGE8/CAVIN1/COL1A1/ABCC3/SOCS3/ALPK2/C3/AXL/CDC42EP1 | 60 |
| SENESE_HDAC2_TARGETS_DN | SENESE_HDAC2_TARGETS_DN | SENESE_HDAC2_TARGETS_DN | 46/1438 | 133/23056 | 0.3458647 | 5.545379 | 13.558589 | 0.0000000 | 0.0000000 | 0.0000000 | C1QTNF12/EDN2/NEXN/OLFML3/LBH/EVA1A/TMEM37/COL3A1/COL5A2/CAVIN2/ACKR3/SEMA3B/TNNC1/WNT5A/GXYLT2/PLAC8/SPP1/EGF/CAP2/ID4/GPNMB/AQP1/PDE1C/TNS3/CCL26/CLU/MATN2/ZCCHC24/EFEMP2/ALDH3B1/CRYAB/TAGLN/SPX/IGFBP6/LUM/DACT1/TPM1/LOXL1/MSLN/KRT17/JUP/COL1A1/ALPK2/BCAM/FOXS1/MYL9 | 46 |
| WINZEN_DEGRADED_VIA_KHSRP | WINZEN_DEGRADED_VIA_KHSRP | WINZEN_DEGRADED_VIA_KHSRP | 40/1438 | 100/23056 | 0.4000000 | 6.413352 | 13.991762 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/EDN2/CCN1/PTGS2/TGFA/CYP26B1/ITGA6/SERPINE2/MUC13/AMOTL2/ARL14/SLC4A4/CXCL8/CXCL3/CXCL2/EREG/PDGFC/FST/TSLP/CSF2/HBEGF/ADRB2/EDN1/RNF144B/CCN2/PDGFA/IL6/INHBA/CAV2/HAS2/PAPPA/DKK1/PPP1R3C/STYK1/GDF15/ZFP36/BMP2/SDC4/CYP24A1/TFAP2C | 40 |
| GOBP_CELL_MATRIX_ADHESION | GOBP_CELL_MATRIX_ADHESION | GOBP_CELL_MATRIX_ADHESION | 61/1438 | 236/23056 | 0.2584746 | 4.144221 | 12.521764 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/CSF1/ITGA10/S100A10/CD34/NID1/ITGB6/ITGA6/ITGA4/COL3A1/FN1/EPHA3/CD96/PHLDB2/ITGB5/BCL6/KDR/NPNT/ADAMTS12/ITGA2/DDR1/PTPRK/CCN2/UTRN/ITGB8/HOXA7/CD36/TRIP6/SERPINE1/ZYX/PLEKHA2/ADAM9/TEK/ITGA8/NRP1/COL13A1/PLAU/VCL/CD44/PTPRJ/EFEMP2/ITGA5/ITGA7/MMP14/AJUBA/NID2/FBLN5/THBS1/ITGA11/MSLN/MSLNL/CDH13/CCR7/JUP/ITGA3/ITGB4/LYPD3/BCAM/RRAS/RIN2/SDC4 | 61 |
| GOBP_EPITHELIAL_CELL_PROLIFERATION | GOBP_EPITHELIAL_CELL_PROLIFERATION | GOBP_EPITHELIAL_CELL_PROLIFERATION | 88/1438 | 451/23056 | 0.1951220 | 3.128464 | 11.773529 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/EPHA2/RUNX3/TIE1/ECM1/CD34/TGFB2/OSR1/TGFA/FAP/ITGA4/NRP2/PPARG/CCR3/WNT5A/COL8A1/CLDN1/HES1/KDR/EPGN/EREG/EGF/VEGFC/SEMA5A/DAB2/FST/SPARC/FGF18/SERPINB1/RREB1/BMP6/CD109/PTPRK/TNFAIP3/IL6/BMPER/CCL26/CAV2/CAV1/PTN/SHH/LOXL2/ZNF703/SULF1/ANGPT1/HAS2/EPPK1/TEK/B4GALT1/NOTCH1/JCAD/NRP1/ALOX5/MMRN2/TCF7L2/FGFR2/HTRA1/EHF/PGR/YAP1/APOA1/WNT10B/KRT4/STAT6/GLI1/IGF1/FLT1/EDNRB/MMP14/PRKD1/BMP4/SIX1/SIX4/ZFP36L1/THBS1/ALDH1A2/NUPR1/CDH13/NOG/SOX9/ZFP36/TGFB1/APOE/C5AR1/BMP2/CEBPB/HMOX1/PDGFB | 88 |
| VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP | 50/1438 | 164/23056 | 0.3048780 | 4.888225 | 12.888007 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/CCN1/S1PR1/SH2D2A/PTGS2/IL1B/NRP2/EPHA4/STAB1/WNT5A/EPHA3/HEG1/FGFR3/KDR/CXCL6/CXCL5/CXCL3/CXCL2/SPP1/VEGFC/OSMR/SPARC/THBS2/PDGFA/IL6/PTN/PLAT/FZD6/ANGPT1/TEK/PTGS1/NRP1/PLAU/FGFR2/ADM/FZD4/MMP1/ROBO4/WNT10B/IGF1/FLT1/TNFAIP2/MMP2/CCL5/GRB7/PECAM1/TGFB1/COL18A1/HMOX1/PDGFB | 50 |
| VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | 52/1438 | 177/23056 | 0.2937853 | 4.710371 | 12.780262 | 0.0000000 | 0.0000000 | 0.0000000 | PRRX1/PRELP/EFEMP1/FAP/COL5A2/FN1/EPHA4/GXYLT2/COL8A1/FSTL1/WWTR1/BCL6/IL1RAP/SLIT2/SPP1/PDGFC/ADAMTS12/DAB2/PRDM6/SPARC/ADAMTS2/GFPT2/PLA2G7/COL12A1/LAMA2/MOXD1/SOD2/THBS2/IL6/GPNMB/INHBA/CAV2/MSR1/SULF1/CTHRC1/FBXO32/CCN4/ST3GAL1/GAS1/ALOX5/PLAU/C3AR1/AMIGO2/PCED1B/NUAK1/FRMD6/NID2/LTBP2/THBS1/FBN1/AXL/BGN | 52 |
| LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | 37/1438 | 89/23056 | 0.4157303 | 6.665562 | 13.811478 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/CTSS/RNASEL/CFH/NID1/ITGB6/FN1/EPHA4/PPARG/TGFBR2/MME/SPP1/SERPINB1/PSMB8/PSMB9/PLA2G7/GPNMB/CD36/PLAT/FABP4/SFTPD/PLAAT3/CASP1/ARHGDIB/KRT7/IGF1/EDNRB/TNFSF13B/LTBP2/ACTC1/BCL2A1/PSMB10/MBP/C3/TGM2/SIM2/SAT1 | 37 |
| WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | WIEDERSCHAIN_TARGETS_OF_BMI1_AND_PCGF2 | 30/1438 | 57/23056 | 0.5263158 | 8.438621 | 14.502058 | 0.0000000 | 0.0000000 | 0.0000000 | S100A2/KCNN3/ITGA4/CCDC80/CLDN1/IL7R/F2RL1/ABLIM3/ADAM19/RREB1/EDN1/MICA/MICB/ITGB8/INHBA/CAV1/CPA4/PODXL/PLAT/TEK/PAPPA/COL5A1/MYOF/ADM/MICAL2/FOSL1/TPM1/CRISPLD2/ITGA3/AXL | 30 |
| RIGGI_EWING_SARCOMA_PROGENITOR_DN | RIGGI_EWING_SARCOMA_PROGENITOR_DN | RIGGI_EWING_SARCOMA_PROGENITOR_DN | 54/1438 | 194/23056 | 0.2783505 | 4.462899 | 12.492170 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/ECM1/PRRX1/PRG4/OSR1/IL1R1/HNMT/NRP2/GALNT15/CDCP1/TMEM158/GXYLT2/HEG1/SLC12A8/MME/VEPH1/CXCL6/FST/F2RL1/GFPT2/ITPR3/RUNX2/CRYBG1/LAMA4/MOXD1/PDK4/PTN/CSGALNACT1/STC1/CLU/COL14A1/HAS2/CCN4/PTGS1/NRP1/PPP1R3C/FIBIN/CD44/PAMR1/C1S/C1R/IGFBP6/LUM/TNFRSF19/BMP4/BDKRB1/CA12/ALDH1A3/PIEZO2/GATA6/PTGIS/APCDD1L/COL6A2/CARD10 | 54 |
| KIM_WT1_TARGETS_UP | KIM_WT1_TARGETS_UP | KIM_WT1_TARGETS_UP | 57/1438 | 216/23056 | 0.2638889 | 4.231031 | 12.304789 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CCN1/CSF1/LAMB3/LBH/BHLHE40/TM4SF1/WWTR1/IL1RAP/ARAP2/CXCL8/EREG/FGF5/LEF1/RAI14/FOXD1/HBEGF/GFPT2/FOXC1/IER3/TPBG/TNFAIP3/SYNJ2/PDGFA/INHBA/TNS3/SERPINE1/FLNC/ZYX/ST3GAL1/VCL/DNMBP/NFKB2/PTPRE/PHLDA2/WT1/CD44/FOSL1/HMGA2/GLIPR1/NFKBIA/ZFP36L1/THBS1/MYO1E/CSPG4/TNFRSF12A/IL4R/KRT17/SOX9/MBP/RELB/IL11/SDC4/DOK5/LIF/CARD10/CSDC2 | 57 |
| FOSTER_TOLERANT_MACROPHAGE_DN | FOSTER_TOLERANT_MACROPHAGE_DN | FOSTER_TOLERANT_MACROPHAGE_DN | 82/1438 | 414/23056 | 0.1980676 | 3.175694 | 11.521121 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/ERRFI1/SPSB1/PDZK1IP1/GBP4/VCAM1/CSF1/S100A10/NIBAN1/PTGS2/PLA2G4A/ITPKB/IL1B/GYPC/SP110/PARP14/CXCL1/CXCL2/CDS1/IL15/TLR3/MYO10/RAI14/HBEGF/EDN1/OGFRL1/TPBG/GJA1/TNFAIP3/CITED2/ADGRG6/MAFK/ITGB8/IL6/FZD1/SERPINE1/CAV1/ZYX/PLEKHA2/CEBPD/ANGPT1/EXT1/DDX58/CEMIP2/COL27A1/TRAF1/NEK6/NOTCH1/IL15RA/MAP3K8/FAS/HHEX/PTPRJ/UBASH3B/RND1/DRAM1/TMEM229B/FOS/EXOC3L4/UACA/TNFRSF12A/IL4R/MT1X/NLRC5/ADAP2/SLFN5/SLFN13/SMIM36/RHBDF2/SOCS3/LIPG/TNFSF9/ZFP36/BCL3/NECTIN2/IL4I1/RIN2/SDC4/MX1/ICOSLG/COL18A1/IL13RA1 | 82 |
| PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | 49/1438 | 164/23056 | 0.2987805 | 4.790461 | 12.563954 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/NUAK2/TGFB2/LBH/TGFA/KYNU/COL7A1/ARL14/FNDC3B/BCL6/CXCL8/CXCL1/CXCL3/CXCL2/EREG/PLAC8/SLC12A7/PLK2/IER3/TAPBP/TNFRSF21/TENT5A/TNFAIP3/CITED2/IL6/INHBA/TNS3/SEMA3C/SERPINE1/TCIM/CEBPD/HAS2/B4GALT1/DKK1/PLAU/NFKB2/TCF7L2/ADM/CD44/GPRC5A/GLIPR1/FOXO1/THBS1/IL4R/SERPINB2/IL27RA/KCNN4/BMP2/LIF | 49 |
| GOBP_OSSIFICATION | GOBP_OSSIFICATION | GOBP_OSSIFICATION | 82/1438 | 419/23056 | 0.1957041 | 3.137798 | 11.389860 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/EPHA2/RUNX3/CCN1/S1PR1/CSF1/ECM1/PTGS2/TGFB2/OSR1/CRIM1/COL5A2/TWIST2/PPARG/WNT5A/WWTR1/IGSF10/OSTN/FGFR3/BMP3/SPP1/NPNT/SGMS2/LEF1/VEGFC/ADAMTS12/ADRB2/FGF18/FOXC1/BMP6/TFAP2A/ID4/RUNX2/TENT5A/GJA1/CCN2/FAM20C/IL6/HOXA2/GLI3/FZD1/PTN/ATP6V0A4/SHH/CSGALNACT1/STC1/CEBPD/CTHRC1/RSPO2/EXT1/CCN4/NOTCH1/ALOX5/DKK1/SRGN/COL13A1/FGFR2/CREB3L1/YAP1/WNT10B/GLI1/IGF1/MMP14/PRKD1/BMP4/SMAD6/ITGA11/SOX8/MMP2/COL1A1/NOG/MRC2/SOX9/TNFRSF11A/FSTL3/TGFB1/BMP2/CEBPB/CYP24A1/RUNX1/MN1/WNT7B | 82 |
| KEGG_ECM_RECEPTOR_INTERACTION | KEGG_ECM_RECEPTOR_INTERACTION | KEGG_ECM_RECEPTOR_INTERACTION | 35/1438 | 84/23056 | 0.4166667 | 6.680575 | 13.451997 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/ITGA10/LAMC2/LAMB3/ITGB6/ITGA6/ITGA4/COL3A1/COL5A2/FN1/COL6A3/LAMB2/ITGB5/SPP1/ITGA2/LAMA4/LAMA2/THBS2/ITGB8/CD36/COL5A1/ITGA8/CD44/VWF/ITGA5/ITGA7/THBS1/ITGA11/ITGA3/COL1A1/ITGB4/SDC4/COL6A2/COL4A6 | 35 |
| ONDER_CDH1_SIGNALING_VIA_CTNNB1 | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | 35/1438 | 84/23056 | 0.4166667 | 6.680575 | 13.451997 | 0.0000000 | 0.0000000 | 0.0000000 | PRRX1/LTBP1/AOX1/COL6A3/MLPH/IL17RC/CXCL8/CXCL1/CXCL2/ADRB2/GALNT10/TNFAIP3/SEMA3C/SERPINE1/PODXL/MICAL2/SAA1/CD82/CREB3L1/BIRC3/TAGLN/SCNN1A/SLC46A3/POSTN/LTBP2/FBLN5/FBN1/TPM1/NUPR1/SOX9/C3/ICAM1/MYL9/KDELR3/BGN | 35 |
| GOBP_REPRODUCTIVE_SYSTEM_DEVELOPMENT | GOBP_REPRODUCTIVE_SYSTEM_DEVELOPMENT | GOBP_REPRODUCTIVE_SYSTEM_DEVELOPMENT | 84/1438 | 437/23056 | 0.1922197 | 3.081931 | 11.332471 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/PTGS2/TGFB2/OSR1/SRD5A2/IL1A/CASP8/SERPINE2/PPARG/WNT5A/FOXL2/MME/HES1/SLIT2/KDR/EREG/SPP1/LEF1/TLR3/FST/CSF2/ADAM19/FOXC1/BMP6/ID4/MDFI/GCM1/GJA1/RSPO3/CITED2/PDGFA/ITGB8/INHBA/GLI3/SEMA3A/PTN/SHH/STC1/PLAG1/SULF1/ZFPM2/DMRTA1/ANXA1/NOTCH1/AKR1C3/FGFR2/HTRA1/PHLDA2/ADM/WT1/FOSL1/FZD4/PGR/YBX3/GLI1/MMP14/BMP4/SIX4/ZFP36L1/ESRRB/CRIP1/CYP19A1/SOX8/NUPR1/SALL1/MMP2/MYOCD/LHX1/KRT19/HOXB13/DLX3/NOG/SOX9/SOCS3/GATA6/C3/AXL/CEBPB/TFAP2C/COL9A3/LIF/PDGFB/WNT7B/NDP | 84 |
| HALLMARK_INTERFERON_GAMMA_RESPONSE | HALLMARK_INTERFERON_GAMMA_RESPONSE | HALLMARK_INTERFERON_GAMMA_RESPONSE | 54/1438 | 200/23056 | 0.2700000 | 4.329013 | 12.195077 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP4/VCAM1/PTGS2/PLA2G4A/CFH/VAMP5/NMI/CASP8/SP110/PARP14/RTP4/IL15/DDX60/PSMB8/PSMB9/TAPBP/TNFAIP3/SOD2/IL6/SAMD9L/PARP12/IDO1/CD274/DDX58/IL15RA/FAS/IFITM2/IFITM3/CASP4/CASP1/C1S/C1R/METTL7B/OASL/LATS2/IRF9/NFKBIA/TNFAIP2/IL4R/MT2A/NLRC5/PSMB10/CCL5/DHX58/IFI35/SOCS3/ICAM1/FPR1/MX2/MX1/USP18/APOL6/IL2RB | 54 |
| HALLMARK_KRAS_SIGNALING_UP | HALLMARK_KRAS_SIGNALING_UP | HALLMARK_KRAS_SIGNALING_UP | 54/1438 | 200/23056 | 0.2700000 | 4.329013 | 12.195077 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/FUCA1/CTSS/PRRX1/PTGS2/CFH/HSD11B1/IL1B/GYPC/GALNT3/TFPI/TMEM158/SEMA3B/EREG/BTC/SPP1/IL7R/ITGA2/F2RL1/CSF2/HBEGF/DOCK2/GFPT2/PSMB8/TNFAIP3/GPNMB/INHBA/PLAT/PDCD1LG2/KLF4/TRAF1/NRP1/HKDC1/PLAU/DNMBP/BIRC3/MMP10/MPZL2/VWA5A/C3AR1/EMP1/LCP1/PLEK2/ALDH1A2/ALDH1A3/JUP/PECAM1/SOX9/PLVAP/SCN1B/KCNN4/CD37/BMP2/LIF | 54 |
| GOBP_CARTILAGE_DEVELOPMENT | GOBP_CARTILAGE_DEVELOPMENT | GOBP_CARTILAGE_DEVELOPMENT | 53/1438 | 194/23056 | 0.2731959 | 4.380253 | 12.194029 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/CCN1/ECM1/PRRX1/WNT9A/OSR1/EFEMP1/BMP10/DLX2/COL3A1/RARB/TGFBR2/WNT5A/FGFR3/NKX3-2/BMP3/ADAMTS12/TGFBI/FGF18/BMP6/EDN1/RUNX2/CCN2/SCIN/ITGB8/HOXA3/GLI3/CSGALNACT1/LOXL2/STC1/SULF1/GDF6/RSPO2/TRPS1/EXT1/CCN4/COL27A1/CD44/SERPINH1/WNT10B/HMGA2/EPYC/BMP4/MAF/HOXB3/COL1A1/NOG/SOX9/TGFB1/BMP2/RUNX1/WNT7B/BGN | 53 |
| GOBP_REGULATION_OF_CELL_CELL_ADHESION | GOBP_REGULATION_OF_CELL_CELL_ADHESION | GOBP_REGULATION_OF_CELL_CELL_ADHESION | 86/1438 | 458/23056 | 0.1877729 | 3.010635 | 11.209472 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ZC3H12A/VCAM1/PTPN22/ILDR2/PTPRC/LAX1/ITPKB/NLRP3/IL1A/IL1B/DPP4/ITGA4/SERPINE2/TGFBR2/WNT5A/BCL6/HES1/LEF1/IL15/MYO10/IL7R/ADAM19/BMP6/ADTRP/HFE/HLA-E/MDGA1/TNFRSF21/VNN1/CITED2/IL6/GPNMB/GLI3/CAV1/PODXL/SHH/ZNF703/IDO1/HAS2/CD274/PDCD1LG2/ANXA1/KLF4/NOTCH1/MAP3K8/ALOX5/SFTPD/CD44/LRRC32/APOA1/UBASH3B/KLRC4-KLRK1/NCKAP1L/TESPA1/IGF1/TNFSF13B/BMP4/IL4R/ADAMTS18/PIEZO1/CCL5/CCR7/C1QTNF1/EMILIN2/MBP/FSTL3/ELANE/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/FXYD5/TGFB1/IL4I1/SIRPG/SIRPA/PRNP/BMP2/SDC4/CEBPB/RUNX1/ICOSLG/LGALS1 | 86 |
| NABA_SECRETED_FACTORS | NABA_SECRETED_FACTORS | NABA_SECRETED_FACTORS | 72/1438 | 343/23056 | 0.2099125 | 3.365607 | 11.384310 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/S100A10/S100A11/TCHH/S100A5/S100A2/S100A16/S100A13/TNFSF18/BRINP3/TGFB2/WNT9A/BMP10/TGFA/IL1A/IL1B/IL36G/WNT5A/FSTL1/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EPGN/EREG/BTC/FGF5/BMP3/EGF/IL15/PDGFC/VEGFC/GDNF/FST/S100Z/CRHBP/CSF2/HBEGF/FGF18/BMP6/PDGFA/IL6/INHBA/CCL26/PTN/SHH/FGF20/GDF6/ANGPT1/IFNE/TNFSF15/WNT10B/IGF1/TNFSF13B/CBLN3/BMP4/CTF1/CCL5/CSF3/FSTL3/EBI3/TNFSF9/TNFSF14/GDF15/TGFB1/IL11/BMP2/LIF/PDGFB/WNT7B | 72 |
| GOBP_LEUKOCYTE_MIGRATION | GOBP_LEUKOCYTE_MIGRATION | GOBP_LEUKOCYTE_MIGRATION | 77/1438 | 385/23056 | 0.2000000 | 3.206676 | 11.261282 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/EDN2/MCOLN2/VCAM1/S1PR1/CSF1/ECM1/TNFSF18/CD34/TGFB2/IL1R1/IL1A/IL1B/DPP4/ITGA6/ITGA4/HRH1/WNT5A/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/VEGFC/ITGA2/F2RL1/ADTRP/EDN1/GPSM3/PLA2G7/IL6/HOXA7/CCL26/SERPINE1/PTN/ARHGEF5/RARRES2/TRIM55/EXT1/B4GALT1/ANXA1/ALOX5/SFTPD/SAA1/C3AR1/KLRC4-KLRK1/EPS8/NCKAP1L/ITGA7/SELPLG/FLT1/EDNRB/MMP14/BDKRB1/THBS1/CYP19A1/CCL5/CCR7/ITGA3/PECAM1/TNFRSF11A/ELANE/TNFSF14/ICAM1/IL27RA/PLVAP/C5AR1/SIRPA/DEFB124/HMOX1/MYH9/RAC2/PDGFB/XG/MSN | 77 |
| GOBP_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | GOBP_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | GOBP_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 53/1438 | 199/23056 | 0.2663317 | 4.270197 | 11.949371 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/CSF1/AGT/DLX2/TGFBR2/WNT5A/SLIT2/KDR/NPNT/LEF1/EGF/ADAMTS16/GDNF/FOXD1/EDN1/DDR1/GCM1/RSPO3/PDGFA/GLI3/SEMA3C/SEMA3A/MET/SHH/SULF1/RSPO2/EXT1/NOTCH1/NRP1/COL13A1/FGFR2/ADM/WT1/PGR/YAP1/MMP14/NFATC4/BMP4/SIX1/SIX4/SOX8/SALL1/FOXF1/LHX1/HOXB7/HOXB13/NOG/SOX9/SOCS3/BMP2/TGM2/CELSR1 | 53 |
| SENESE_HDAC1_AND_HDAC2_TARGETS_UP | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | 59/1438 | 243/23056 | 0.2427984 | 3.892878 | 11.692203 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/TIE1/PRRX1/LAMC2/IL1A/KYNU/ITGA6/FN1/EPHA4/COL6A3/IRAK2/TGFBR2/TMEM158/AADAC/FGFRL1/CXCL8/CXCL5/CXCL3/EREG/GPAT3/TRIML2/IL7R/OSMR/ADAMTS6/CSF2/GFPT2/TRIM38/TMEM200A/TNFAIP3/TNFRSF11B/HAS2/ST3GAL1/DKK1/SRGN/PLAU/NFKB2/NRIP3/MICAL2/SAA1/FOSL1/BIRC3/MMP1/ELMOD1/UBASH3B/ROBO4/NAV3/SERPINA1/RBPMS2/BCL2A1/TNFRSF12A/CES1/SLC16A3/SERPINB2/C3/IL11/BMP2/TGM2/MAP3K7CL/RAC2 | 59 |
| MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | 62/1438 | 269/23056 | 0.2304833 | 3.695426 | 11.468700 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/PDZK1IP1/RAB7B/ACTG2/CAPG/GALNT3/FN1/TMEM40/CDCP1/TMEM158/COL7A1/SLCO2A1/BCL6/SPON2/PLAC8/SPP1/IRX2/NPR3/PLK2/DSP/ID4/DDR1/PLA2G7/TPBG/PTPRK/PERP/THBS2/SCIN/PTN/PDLIM2/PLAT/FZD6/TRPS1/FBXO32/CEMIP2/GAS1/NFKB2/FGFR2/HTRA1/EHF/VWF/KRT7/KRT8/KRT18/IGFBP6/FOS/TNFAIP2/THBS1/MFGE8/TNFRSF12A/COTL1/CLDN7/KRT19/ABCC3/SOX9/CNN1/TGM2/SDC4/TFAP2C/ADAMTS5/RUNX1/SAT1 | 62 |
| SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | 84/1438 | 453/23056 | 0.1854305 | 2.973077 | 10.938666 | 0.0000000 | 0.0000000 | 0.0000000 | ARHGEF16/ERRFI1/DHRS3/TINAGL1/ECM1/PLA2G4A/ELF3/EFEMP1/TMEM37/RPRM/DNER/ACKR3/TMEM40/SEMA3B/EPHA3/SLCO2A1/PLSCR2/FGFR3/SULT1E1/ANXA3/PLAC8/CTSO/PDGFC/ADAMTS16/EDN1/HLA-E/MDFI/NT5E/CRYBG1/TPD52L1/RSPO3/CITED2/TMEM184A/SKAP2/PRR15/TSPAN12/PTN/ARHGEF5/SHH/PDLIM2/CLU/TCIM/CEBPD/LRATD2/ST3GAL1/AQP3/ANXA1/PTGR1/GSN/AIF1L/HKDC1/ANKRD1/CYP26A1/MYOF/FGFR2/SCNN1A/KRT7/CPM/NFKBIA/ALDH1A2/ALDH1A3/ACSM3/MT1X/NQO1/MAF/CRISPLD2/GLP2R/KRT13/KRT15/KRT19/HOXB13/SOX9/LLGL2/ITGB4/MBP/KCNN4/TFAP2C/COL9A3/CLIC6/APOL3/COL4A6/COL4A5/PLS3/TENM1 | 84 |
| GOMF_INTEGRIN_BINDING | GOMF_INTEGRIN_BINDING | GOMF_INTEGRIN_BINDING | 46/1438 | 156/23056 | 0.2948718 | 4.727791 | 12.048984 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/VCAM1/ITGA10/IL1B/ITGB6/FAP/ITGA6/ITGA4/COL3A1/FN1/LAMB2/ITGB5/KDR/SPP1/NPNT/ITGA2/EDIL3/TGFBI/CCN2/UTRN/ITGB8/GPNMB/PTPRZ1/PTN/ADAM9/CCN4/S1PR3/COL5A1/ITGA8/ADAMTS8/VWF/ITGA5/ITGA7/IGF1/LCP1/MMP14/FBLN5/THBS1/FBN1/ITGA11/MFGE8/ITGA3/ITGB4/ICAM1/ADAMTS5/MYH9 | 46 |
| GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | 50/1438 | 183/23056 | 0.2732240 | 4.380705 | 11.842012 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/OLFML3/C1orf54/ECM1/ADAMTSL4/S100A16/S100A13/OPTC/OSR1/ACTG2/COL3A1/EPHA4/PLSCR2/MME/FGF5/NPR3/OSMR/DAB2/FST/F2RL1/STING1/ADAMTS2/SERPINB1/NT5E/ADGRG6/AHR/BMPER/PLAT/CEBPD/MATN2/TNFRSF11B/TEK/GAS1/MAP3K8/PLAC9/DRAM1/NUAK1/BMP4/ZFP36L1/LTBP2/IL4R/RRAD/C1QTNF1/EMILIN2/CNN1/COL6A2/CARD10/PDGFB/GPC4/ZNF185 | 50 |
| LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | 50/1438 | 183/23056 | 0.2732240 | 4.380705 | 11.842012 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/FUCA1/S100A10/CRIM1/IL1R1/TFPI/SP100/TGFBR2/MITF/MYLK/AMOTL2/FGFR3/KDR/ANXA3/CDS1/SPP1/CTSO/DAB2/IQGAP2/SEMA3C/CAV2/PODXL/CLU/RBPMS/CEBPD/MATN2/ANGPT1/TEK/AKR1C3/PLAU/PPP1R3C/MYOF/AHNAK/LRRC32/CRYAB/CA12/ACSM3/KIFC3/MAF/KRT19/LLGL2/IL27RA/BLVRB/AXL/APOE/PRNP/MYH9/CARD10/COL4A5/PLS3 | 50 |
| KIM_GLIS2_TARGETS_UP | KIM_GLIS2_TARGETS_UP | KIM_GLIS2_TARGETS_UP | 34/1438 | 85/23056 | 0.4000000 | 6.413352 | 12.895554 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/FCGR2A/CFH/NID1/COL3A1/TGFBR2/IGSF10/OSMR/TGFBI/SPARC/ADAMTS2/PSMB8/PSMB9/CCN2/SERPINE1/PDGFRL/MATN2/COL14A1/IFITM3/EFEMP2/CASP4/LUM/POSTN/TNFSF13B/MMP14/LTBP2/FBN1/BCL2A1/CCL5/COL1A1/SOCS3/C3/ICAM1/COL18A1 | 34 |
| ZHU_CMV_ALL_DN | ZHU_CMV_ALL_DN | ZHU_CMV_ALL_DN | 40/1438 | 119/23056 | 0.3361345 | 5.389371 | 12.381172 | 0.0000000 | 0.0000000 | 0.0000000 | EFEMP1/HNMT/COL3A1/COL5A2/ACKR3/LAMB2/MITF/MYLK/SULT1E1/CRHBP/TFAP2A/TENT5A/LAMA4/THBS2/AHR/SERPINE1/CEBPD/TPM2/ANXA1/GAS1/MBL2/TCF7L2/ADM/MMP1/TAGLN/TNFRSF1A/C1R/POSTN/BMP4/ZFP36L1/THBS1/ANPEP/COL1A1/CNN2/APOE/PTGIS/RUNX1/COL6A2/MN1/MYH9 | 40 |
| SCHOEN_NFKB_SIGNALING | SCHOEN_NFKB_SIGNALING | SCHOEN_NFKB_SIGNALING | 22/1438 | 34/23056 | 0.6470588 | 10.374540 | 14.108217 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/CCN1/CTSS/PTGS2/NUAK2/IL1A/IL1B/FN1/BCL6/CXCL8/CXCL2/CSF2/EDN1/CCN2/SULF1/KLF4/HHEX/BIRC3/NFKBIA/THBS1/GADD45B/C3 | 22 |
| PHONG_TNF_TARGETS_UP | PHONG_TNF_TARGETS_UP | PHONG_TNF_TARGETS_UP | 29/1438 | 63/23056 | 0.4603175 | 7.380445 | 13.079094 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/LAMC2/NUAK2/BHLHE40/CXCL8/CXCL1/CXCL3/CXCL2/EREG/PLK2/CSF2/IER3/TNFAIP3/IL6/INHBA/CEBPD/PLAU/NFKB2/CD44/BIRC3/NFKBIA/FOS/TNFAIP2/ICAM1/ZFP36/IL11/BMP2/SDC4/LIF | 29 |
| GOMF_HEPARIN_BINDING | GOMF_HEPARIN_BINDING | GOMF_HEPARIN_BINDING | 47/1438 | 168/23056 | 0.2797619 | 4.485529 | 11.694284 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/LAMC2/CFH/PTPRC/LGR6/PRELP/NRP2/FN1/SERPINE2/CCDC80/FSTL1/FGFRL1/SLIT2/SOD3/ADAMTS3/CXCL8/CXCL6/HBEGF/RSPO3/CCN2/THBS2/TMEM184A/GPNMB/PTN/RSPO2/CCN4/COL5A1/NRP1/COL13A1/FGFR2/SAA1/EFEMP2/ADAMTS8/ADAMTS15/POSTN/BMP4/LTBP2/SERPINA10/THBS1/FBN1/CRISPLD2/LIPG/ELANE/ADAMTSL5/APOE/ADAMTS5/TENM1 | 47 |
| WALLACE_PROSTATE_CANCER_RACE_UP | WALLACE_PROSTATE_CANCER_RACE_UP | WALLACE_PROSTATE_CANCER_RACE_UP | 65/1438 | 303/23056 | 0.2145215 | 3.439504 | 11.024471 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/IFI44L/GBP1/CD53/PTPN22/C1orf54/CTSS/IFI16/PTPRC/PTPN7/NID1/RASGRP3/ITGA4/TMEM158/JCHAIN/PLAC8/IL15/DDX60/IL7R/HLA-E/PSMB8/PSMB9/COL21A1/PDK4/PARP12/ADAM28/CLU/IDO1/TCIM/CEBPD/MYBL1/CCN4/JCAD/SRGN/IFITM2/IFITM3/MS4A4A/NCKAP1L/CPM/GLIPR1/ALOX5AP/DNAJC15/IRF9/AHNAK2/FBN1/BCL2A1/ANPEP/COTL1/HS3ST3A1/SLFN12/CCL5/CCR7/PECAM1/CNN1/GMFG/APOE/C5AR1/CD37/THBD/MX2/MX1/APOL6/APOL1/RAC2/APOBEC3G | 65 |
| GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 81/1438 | 441/23056 | 0.1836735 | 2.944907 | 10.635893 | 0.0000000 | 0.0000000 | 0.0000000 | EDN2/GBP5/S1PR1/CSF1/IFI16/PTGS2/IKBKE/AGT/IL1B/NMI/WNT5A/SUCNR1/SLIT2/TXK/KDR/CXCL8/EREG/IL15/DDX60/VEGFC/TLR3/SEMA5A/OSMR/ITGA2/F2RL1/TSLP/STING1/FGF18/BMP6/EDN1/HLA-E/GPSM3/PLA2G7/TPBG/SASH1/RAET1E/IL6/CCL26/TRIM56/SERPINE1/MET/PTN/RARRES2/IDO1/FABP4/CCN4/NRP1/MBL2/TRIM5/CASP1/TNFRSF1A/C3AR1/KLRD1/KLRC4-KLRK1/NCKAP1L/OASL/ALOX5AP/PRKD1/NFKBIA/THBS1/NUPR1/NLRC5/CDH13/CCL5/CCR7/DHX58/IFI35/EMILIN2/TNFRSF11A/CREB3L3/TNFSF14/C3/TGFB1/NECTIN2/C5AR1/THBD/DEFB124/CEBPB/RAC2/LGALS1/PDGFB | 81 |
| GOBP_EMBRYONIC_ORGAN_DEVELOPMENT | GOBP_EMBRYONIC_ORGAN_DEVELOPMENT | GOBP_EMBRYONIC_ORGAN_DEVELOPMENT | 82/1438 | 451/23056 | 0.1818182 | 2.915160 | 10.593643 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ECE1/CCN1/PIFO/TBX15/PRRX1/TGFB2/OSR1/EFEMP1/DLX2/CASP8/RARB/TGFBR2/WNT5A/FOXL2/HES1/NKX3-2/KDR/CXCL8/LEF1/PDGFC/GDNF/CSF2/FOXC1/TFAP2A/EDN1/MDFI/RUNX2/GCM1/TBX18/GJA1/RSPO3/CITED2/PDGFA/HOXA1/HOXA2/HOXA3/HOXA7/GLI3/RARRES2/SHH/FZD6/CTHRC1/ZFPM2/PCSK5/CRB2/NOTCH1/ITGA8/COL13A1/FGFR2/HMX3/PHLDA2/ADM/MICAL2/ALX4/YAP1/GLI1/MMP14/BMP4/SIX1/SIX4/ZFP36L1/ESRRB/FBN1/ALDH1A2/RBPMS2/ALDH1A3/SALL1/FOXF1/LHX1/KRT19/HOXB2/HOXB3/HOXB7/NOG/SOX9/SOCS3/TGFB1/CEBPB/LIF/PDGFB/WNT7B | 82 |
| GHANDHI_BYSTANDER_IRRADIATION_UP | GHANDHI_BYSTANDER_IRRADIATION_UP | GHANDHI_BYSTANDER_IRRADIATION_UP | 33/1438 | 84/23056 | 0.3928571 | 6.298828 | 12.547994 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/PLA2G4A/LAMB3/HSD11B1/IL1A/IL1B/KYNU/CXCL8/CXCL1/CXCL5/CXCL3/CXCL2/SLC7A11/TSLP/TNFAIP3/SOD2/AHR/INHBA/STC1/TCIM/IFNE/TNFSF15/BIRC3/MMP10/MMP1/MMP3/PLEK2/BCL2A1/MT1X/SERPINB2/RELB/LIF/SAT1 | 33 |
| GOBP_LEUKOCYTE_CELL_CELL_ADHESION | GOBP_LEUKOCYTE_CELL_CELL_ADHESION | GOBP_LEUKOCYTE_CELL_CELL_ADHESION | 74/1438 | 381/23056 | 0.1942257 | 3.114095 | 10.731676 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ZC3H12A/VCAM1/PTPN22/ILDR2/PTPRC/LAX1/ITPKB/NLRP3/IL1A/IL1B/DPP4/ITGA4/TGFBR2/BCL6/HES1/LEF1/IL15/IL7R/ADTRP/HFE/HLA-E/TNFRSF21/NT5E/VNN1/IL6/GPNMB/GLI3/CAV1/SHH/IDO1/EXT1/HAS2/CD274/PDCD1LG2/ANXA1/KLF4/MAP3K8/ALOX5/SFTPD/CD44/LRRC32/KLRC4-KLRK1/ITGA5/NCKAP1L/TESPA1/IGF1/SELPLG/TNFSF13B/BMP4/IL4R/CCL5/CCR7/PECAM1/ELANE/EBI3/TNFSF9/CD70/TNFSF14/CLEC4M/ICAM1/IL27RA/IL12RB1/IL4I1/SIRPG/SIRPA/PRNP/SDC4/CEBPB/RUNX1/ICOSLG/RAC2/LGALS1/MSN | 74 |
| ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE | ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE | ANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE | 29/1438 | 64/23056 | 0.4531250 | 7.265125 | 12.944510 | 0.0000000 | 0.0000000 | 0.0000000 | PRRX1/FAP/COL3A1/COL5A2/FN1/COL6A3/TMEM158/LRRC15/SPARC/THBS2/INHBA/LOXL2/SULF1/COL5A1/PLAU/EPYC/LUM/NUAK1/POSTN/NID2/FBN1/MMP2/CRISPLD2/COPZ2/COL1A1/COL6A2/LGALS1/MXRA5/BGN | 29 |
| WINTER_HYPOXIA_METAGENE | WINTER_HYPOXIA_METAGENE | WINTER_HYPOXIA_METAGENE | 57/1438 | 243/23056 | 0.2345679 | 3.760916 | 11.158849 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/EDN2/RNASEL/PTGS2/ELF3/TGFA/COL5A2/FN1/BHLHE40/KDR/CXCL8/SPP1/EGF/VEGFC/ELL2/TGFBI/EDN1/TPBG/NT5E/TNFAIP3/CITED2/THBS2/IL6/SERPINE1/MET/TEK/ANXA1/PTGS1/COL5A1/PLAU/NFKB2/ADM/BHLHE41/KRT18/ITGA5/FLT1/FOS/THBS1/ANXA2/CA12/ALDH1A3/MMP2/KRT19/HAP1/SERPINB2/ICAM1/TGFB1/SLC6A16/SIRPA/TGM2/BACE2/HMOX1/LGALS1/PDGFB/ARSL/SAT1/COL4A5 | 57 |
| MEBARKI_HCC_PROGENITOR_WNT_UP_BLOCKED_BY_FZD8CRD | MEBARKI_HCC_PROGENITOR_WNT_UP_BLOCKED_BY_FZD8CRD | MEBARKI_HCC_PROGENITOR_WNT_UP_BLOCKED_BY_FZD8CRD | 40/1438 | 125/23056 | 0.3200000 | 5.130681 | 11.943166 | 0.0000000 | 0.0000000 | 0.0000000 | SPOCD1/TGFB2/IL1R1/LYPD1/COL3A1/COL5A2/FN1/CDCP1/TMEM158/PRICKLE2/STK32B/LEF1/NKD2/HAPLN1/RBM24/MDFI/RSPO3/MOXD1/THBS2/SEMA3C/SERPINE1/TRIM55/EXT1/FIBCD1/CLIC3/PAMR1/PRSS23/LAYN/ARHGDIB/EPYC/LUM/LCP1/BMF/FBN1/CRISPLD2/NOG/MILR1/MYH9/KLHL4/SRPX2 | 40 |
| REACTOME_COLLAGEN_FORMATION | REACTOME_COLLAGEN_FORMATION | REACTOME_COLLAGEN_FORMATION | 34/1438 | 90/23056 | 0.3777778 | 6.057055 | 12.397396 | 0.0000000 | 0.0000000 | 0.0000000 | CTSS/LAMC2/LAMB3/ITGA6/COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/P3H2/ADAMTS3/ADAMTS2/COL21A1/COL19A1/COL12A1/COL26A1/LOXL2/COL14A1/COL27A1/COL5A1/COL13A1/TLL2/LOXL4/P4HA3/SERPINH1/MMP3/LOXL1/COL1A1/ITGB4/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 34 |
| GOBP_AMEBOIDAL_TYPE_CELL_MIGRATION | GOBP_AMEBOIDAL_TYPE_CELL_MIGRATION | GOBP_AMEBOIDAL_TYPE_CELL_MIGRATION | 85/1438 | 482/23056 | 0.1763485 | 2.827463 | 10.457362 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ZC3H12A/EDN2/S100A2/PTGS2/ATP2B4/TGFB2/AGT/BMP10/DPP4/FAP/ITGA4/NRP2/FN1/SP100/PPARG/TGFBR2/SEMA3B/WNT5A/FSTL1/AMOTL2/SLIT2/KDR/ANXA3/EGF/VEGFC/SEMA5A/GDNF/ITGA2/PLK2/HBEGF/SPARC/FGF18/RREB1/ADTRP/EDN1/TPBG/GJA1/SASH1/BMPER/SEMA3C/SEMA3A/SEMA3D/EPHB4/MET/PTN/SHH/LOXL2/STC1/ADAM9/ANGPT1/HAS2/EPPK1/TEK/ANXA1/KLF4/CRB2/NOTCH1/JCAD/NRP1/MMRN2/APOA1/ARHGDIB/EDNRB/PRKD1/BMP4/THBS1/SOX8/CDH13/JUP/ITGA3/SOX9/ITGB4/SEMA6B/TGFB1/APOE/RRAS/HAS1/RIN2/SDC4/HMOX1/MYH9/CARD10/PDGFB/SRPX2 | 85 |
| WP_MALIGNANT_PLEURAL_MESOTHELIOMA | WP_MALIGNANT_PLEURAL_MESOTHELIOMA | WP_MALIGNANT_PLEURAL_MESOTHELIOMA | 81/1438 | 446/23056 | 0.1816143 | 2.911892 | 10.515616 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CSF1/LAMC2/RASSF5/LAMB3/NLRP3/TGFA/ACTG2/IL1B/ITGA6/ITGA4/FN1/LAMB2/WNT5A/WWTR1/FGFR3/KDR/RASSF6/CXCL1/CXCL5/BTC/FGF5/LEF1/EGF/PDGFC/VEGFC/CDH9/ITGA2/CSF2/HBEGF/SPARC/FGF18/ITPR3/LAMA4/LAMA2/CCN2/PDGFA/IL6/FZD1/MET/PODXL/FGF20/IDO1/FABP4/FZD6/CTHRC1/ANGPT1/CD274/TEK/FZD8/DKK1/PLAU/TCF7L2/FGFR2/CD44/FOSL1/PRSS23/YAP1/MMP3/CASP1/WNT10B/IGF1/LATS2/FLT3/FLT1/FOXO1/MMP14/AJUBA/ACTC1/MMP2/CDH13/CDH15/CCL5/CSF3/ITGA3/ITGB4/TGFB1/PDGFB/WNT7B/COL4A6/COL4A5 | 81 |
| HALLMARK_MYOGENESIS | HALLMARK_MYOGENESIS | HALLMARK_MYOGENESIS | 51/1438 | 200/23056 | 0.2550000 | 4.088512 | 11.314058 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/CASQ1/COL3A1/DES/COL6A3/BHLHE40/VIPR1/TNNC1/MYLK/ITGB5/WWTR1/SOD3/FST/HBEGF/SPARC/TPD52L1/LAMA2/MYL7/CD36/CLU/TPM2/GSN/NOTCH1/MYOZ1/PPP1R3C/PYGM/CRYAB/TAGLN/ITGA7/IGF1/ACTC1/CTF1/KIFC3/NQO1/CDH13/MYH8/MYH4/MYH1/MYH2/MYL4/SGCA/COL1A1/ITGB4/MYOM1/GADD45B/TGFB1/CKM/PRNP/PTGIS/COL6A2/MYH9 | 51 |
| MARKEY_RB1_ACUTE_LOF_DN | MARKEY_RB1_ACUTE_LOF_DN | MARKEY_RB1_ACUTE_LOF_DN | 55/1438 | 230/23056 | 0.2391304 | 3.834069 | 11.140731 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/MCOLN2/GBP2/GBP4/CRABP2/IFI16/PRRX1/PTPRC/SP100/BHLHE40/UBA7/STAB1/CXCL3/PLAC8/NPR3/IL7R/TGFBI/HLA-E/PSMB8/PSMB9/TAPBP/PLA2G7/NT5E/SOD2/SKAP2/PCSK5/SRGN/TRIM5/MMP10/MMP3/CASP4/C3AR1/KRT7/NCKAP1L/SELPLG/LCP1/IRF9/TMEM229B/ALDH1A2/BCL2A1/NUPR1/MT1X/PSMB10/CCL5/IFI35/SOCS3/TNFSF9/ADGRE1/GMFG/FPR1/PROCR/USP18/RAC2/SAT1/GPC4 | 55 |
| NABA_ECM_REGULATORS | NABA_ECM_REGULATORS | NABA_ECM_REGULATORS | 56/1438 | 238/23056 | 0.2352941 | 3.772560 | 11.088809 | 0.0000000 | 0.0000000 | 0.0000000 | MMP23B/ADAMTSL4/CTSS/AGT/SERPINE2/ITIH3/P3H2/CPN2/ADAMTS3/CTSO/ADAMTS16/ADAMTS12/ADAMTS6/ADAM19/ADAMTS2/SERPINB1/CD109/FAM20C/SERPINE1/LOXL2/ADAM28/HTRA4/ADAM9/ADAM32/PLAT/SULF1/PCSK5/PAPPA/PLAU/TLL2/LOXL4/HTRA1/PAMR1/P4HA3/SERPINH1/MMP10/MMP1/MMP3/ADAMTS8/ADAMTS15/SERPINE3/MMP14/SERPINA10/SERPINA6/SERPINA1/LOXL1/MMP2/ADAMTS18/SERPINB7/SERPINB2/SERPINB8/ELANE/ADAMTSL5/ADAM33/TGM2/ADAMTS5 | 56 |
| VERHAAK_AML_WITH_NPM1_MUTATED_UP | VERHAAK_AML_WITH_NPM1_MUTATED_UP | VERHAAK_AML_WITH_NPM1_MUTATED_UP | 49/1438 | 187/23056 | 0.2620321 | 4.201260 | 11.336328 | 0.0000000 | 0.0000000 | 0.0000000 | FCGR2A/PLA2G4A/LTBP1/RASGRP3/IL1B/HNMT/BCL6/CXCL3/CXCL2/EREG/SNCAIP/FOXC1/IER3/RHAG/VNN1/VNN2/TNFAIP3/SOD2/IL6/HOXA7/CD36/CLU/NFKB2/SLC15A3/CASP1/C3AR1/NFKBIA/SERPINA1/TNFAIP2/THBS1/BCL2A1/MMP2/HOXB2/HOXB3/KCNJ2/SLC16A3/PIEZO2/SERPINB2/ADGRE1/GDF15/C5AR1/FPR1/RUNX1/GGT1/HMOX1/LGALS2/APOBEC3A/SAT1/COL4A5 | 49 |
| GOBP_KIDNEY_EPITHELIUM_DEVELOPMENT | GOBP_KIDNEY_EPITHELIUM_DEVELOPMENT | GOBP_KIDNEY_EPITHELIUM_DEVELOPMENT | 42/1438 | 140/23056 | 0.3000000 | 4.810014 | 11.662064 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/AGT/OSR1/EPHA4/RARB/LAMB2/WWTR1/HES1/SLIT2/NPNT/IRX2/ADAMTS16/GDNF/FOXD1/FOXC1/SIM1/BMPER/GLI3/PODXL/SHH/EXT1/NOTCH1/FGFR2/WT1/YAP1/EDNRB/BMP4/SIX1/SIX4/MYO1E/SMAD6/SOX8/SALL1/LHX1/HOXB7/NOG/PECAM1/SOX9/BMP2/SDC4/LIF/WNT7B | 42 |
| BRUECKNER_TARGETS_OF_MIRLET7A3_DN | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | 31/1438 | 76/23056 | 0.4078947 | 6.539931 | 12.476432 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/LBH/EFEMP1/NRP2/FN1/PPARG/CXCL1/CXCL5/CXCL3/ANXA3/PLK2/SPARC/GALNT10/AKR1B10/LOXL2/MATN2/COL5A1/PLAAT3/PRSS23/NNMT/PCED1B/DIO2/LACTB/BCL2A1/MFGE8/MT2A/MT1X/COTL1/CD70/RIN2/COL4A6 | 31 |
| NABA_ECM_GLYCOPROTEINS | NABA_ECM_GLYCOPROTEINS | NABA_ECM_GLYCOPROTEINS | 50/1438 | 196/23056 | 0.2551020 | 4.090148 | 11.205299 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/TINAGL1/CCN1/ECM1/LAMC2/HMCN1/LAMB3/NID1/LTBP1/CRIM1/VIT/EFEMP1/FN1/LAMB2/IGSF10/SPON2/SLIT2/SPP1/NPNT/EDIL3/TGFBI/SPARC/LAMA4/RSPO3/LAMA2/CCN2/THBS2/BMPER/MATN2/CTHRC1/RSPO2/CCN4/MMRN2/TECTB/EFEMP2/VWA5A/VWF/IGFBP6/POSTN/NID2/LTBP2/FBLN5/THBS1/FBN1/GLDN/MFGE8/CRISPLD2/EMILIN2/MXRA5/SRPX2 | 50 |
| HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | 31/1438 | 77/23056 | 0.4025974 | 6.454997 | 12.365981 | 0.0000000 | 0.0000000 | 0.0000000 | FUCA1/OLFML3/TGFA/SERPINE2/P3H2/CXCL8/CXCL6/CXCL1/EDIL3/IER3/HLA-C/FILIP1/TNFAIP3/IL6/INHBA/CLU/FABP4/ADM/CREB3L1/TAGLN/NUAK1/FBN1/IL32/ITGA3/ACSF2/ICAM1/CNN1/APOE/RELB/SDC4/MX1 | 31 |
| BILD_HRAS_ONCOGENIC_SIGNATURE | BILD_HRAS_ONCOGENIC_SIGNATURE | BILD_HRAS_ONCOGENIC_SIGNATURE | 57/1438 | 250/23056 | 0.2280000 | 3.655611 | 10.888400 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/PTGS2/TGFB2/TGFA/IL1A/IL1B/FN1/EPHA4/CDCP1/BCL6/CXCL8/CXCL1/CXCL5/CXCL3/CXCL2/EREG/GPAT3/IRX2/ITGA2/HBEGF/ADRB2/SERPINB1/IER3/ITPR3/COL12A1/NT5E/PDGFA/TNFRSF10A/CD274/GAS1/COL27A1/ITPRIP/TCF7L2/FGFR2/PTPRE/PHLDA2/FOSL1/CASP1/ADAMTS15/NAV3/MMP14/FOS/AHNAK2/TNFRSF12A/SLC16A3/SERPINB2/GDF15/ZFP36/KCNN4/IL11/PRNP/BMP2/SDC4/ADAMTS5/RUNX1/LIF/MID1 | 57 |
| LEI_MYB_TARGETS | LEI_MYB_TARGETS | LEI_MYB_TARGETS | 66/1438 | 323/23056 | 0.2043344 | 3.276171 | 10.625073 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/S100A10/CRABP2/LAMC2/CRIM1/IL1B/FAP/FN1/SERPINE2/COL6A3/BHLHE40/TMEM158/TM4SF1/CXCL8/ANXA3/DAB2/PLK2/TGFBI/SPARC/TFAP2A/DDR1/MICB/ITPR3/GJA1/ADGRG6/IL6/TRIP6/SERPINE1/CAV1/CLU/ANXA1/SRGN/VCL/IFITM2/SAA1/PRSS23/MMP1/CRYAB/NNMT/KRT7/KRT8/KRT18/STAT6/LUM/AHNAK2/ANXA2/TPM1/CA12/NUPR1/MT1X/RRAD/CLDN7/KRT15/KRT19/KRT17/JUP/SLC16A3/SERPINB2/AXL/MYL9/TGM2/CEBPB/TFAP2C/HMOX1/SAT1/MSN | 66 |
| FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP | FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP | FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_UP | 73/1438 | 383/23056 | 0.1906005 | 3.055970 | 10.464441 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/S100A2/RNASEL/LAMC2/LAX1/NUAK2/PTPN14/MAP1LC3C/SULT1C2/KCNE4/SP140L/RARB/CDCP1/WNT5A/EPHA3/COL8A1/CD96/PARP14/TM4SF1/WWTR1/TMEM212/TECRL/ENAM/EREG/FGF5/ARHGAP24/TLR3/ADAMTS6/S100Z/ERAP2/ADTRP/HFE/RHAG/LGSN/DDO/SASH1/MACC1/BMPER/FOXP2/CADPS2/ASB15/CPA4/TCAF2/STC1/TMEM236/NRP1/MYPN/SLC16A12/PRRG4/EHF/PAMR1/PTPRJ/NNMT/KLRD1/TESPA1/PPM1H/MSRB3/BEST3/FLT1/SIX4/THBS1/CGNL1/BNC1/MYOCD/ABCA9/SLC14A2/SLC14A1/CD22/NFATC2/APOL6/APOL1/APOBEC3A/TBC1D8B | 73 |
| MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_DEPENDENT | MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_DEPENDENT | MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_DEPENDENT | 33/1438 | 88/23056 | 0.3750000 | 6.012517 | 12.150381 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/CCN1/GBP1/HMCN1/IL1R1/LYPD1/COL3A1/COL5A2/PRICKLE2/CCDC80/SLC12A8/CXCL3/LEF1/NKD2/HAPLN1/SPARC/RBM24/SEMA3C/SERPINE1/CTHRC1/PCSK5/CLIC3/PAMR1/EPYC/LUM/LCP1/DACT1/CRISPLD2/COL1A1/NOG/ITGB4/KLHL4/SRPX2 | 33 |
| GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 78/1438 | 429/23056 | 0.1818182 | 2.915160 | 10.327007 | 0.0000000 | 0.0000000 | 0.0000000 | C1QTNF12/TNFRSF1B/IFI16/PTPRC/CD34/NLRP3/NMI/DPP4/FAP/TFPI/EPHA4/SERPINE2/PPARG/SEMA3B/WNT5A/CD96/PHLDB2/PARP14/SLIT2/SPP1/GRID2/SEMA5A/PLK2/ADTRP/EDN1/TRIM38/HLA-E/MICA/MICB/CD109/NT5E/TNFAIP3/PDGFA/SEMA3C/SEMA3A/SEMA3D/SERPINE1/PLAT/EPPK1/TEK/KLF4/NOTCH1/NRP1/ALOX5/MYOZ1/PLAU/HTRA1/NLRP6/SAA1/CARD16/APOA1/UBASH3B/TNFRSF1A/KLRD1/KLRC4-KLRK1/SPX/IGF1/LRFN5/THBS1/CYP19A1/NLRC5/ADAMTS18/FOXF1/DHX58/RHBDF2/SOCS3/C1QTNF1/METRNL/SERPINB2/ELANE/SEMA6B/ZFP36/APOE/SIRPA/THBD/PTGIS/USP18/PDGFB | 78 |
| KEGG_FOCAL_ADHESION | KEGG_FOCAL_ADHESION | KEGG_FOCAL_ADHESION | 50/1438 | 199/23056 | 0.2512563 | 4.028487 | 11.066160 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/LAMC2/LAMB3/ITGB6/ITGA6/ITGA4/COL3A1/COL5A2/FN1/COL6A3/LAMB2/MYLK/ITGB5/KDR/SPP1/EGF/PDGFC/VEGFC/ITGA2/LAMA4/LAMA2/THBS2/PDGFA/ITGB8/MYL7/CAV2/CAV1/MET/FLNC/ZYX/COL5A1/ITGA8/VCL/BIRC3/VWF/ITGA5/ITGA7/IGF1/FLT1/THBS1/ITGA11/MYLK3/ITGA3/COL1A1/ITGB4/MYL9/COL6A2/RAC2/PDGFB/COL4A6 | 50 |
| HORIUCHI_WTAP_TARGETS_UP | HORIUCHI_WTAP_TARGETS_UP | HORIUCHI_WTAP_TARGETS_UP | 64/1438 | 309/23056 | 0.2071197 | 3.320829 | 10.592895 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/CSF1/OLFML3/HMCN1/CFH/TGFA/IL1R1/HNMT/ITGA4/TFPI/SERPINE2/FNDC3B/LPP/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/CFI/IL15/TLR3/IL7R/OSMR/TAPBP/CD109/TMEM200A/TNFAIP3/SOD2/TCIM/CEBPD/GLIS3/KLF4/COL27A1/PAPPA/PTGS1/COL5A1/PPP1R3C/ACSL5/PLAAT4/LRRC32/BIRC3/CASP1/TAGLN/H2AJ/FLT1/EDNRB/PLEK2/ZFP36L1/FBN1/ADAMTS18/PITPNM3/HOXB7/KCNJ2/COLEC12/TNFRSF11A/ICAM1/CDC42EP5/PRNP/MYL9/SDC4/CEBPB/HMOX1/APOL1/ITM2A | 64 |
| JINESH_BLEBBISHIELD_TO_IMMUNE_CELL_FUSION_PBSHMS_UP | JINESH_BLEBBISHIELD_TO_IMMUNE_CELL_FUSION_PBSHMS_UP | JINESH_BLEBBISHIELD_TO_IMMUNE_CELL_FUSION_PBSHMS_UP | 74/1438 | 395/23056 | 0.1873418 | 3.003722 | 10.359784 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/EPHA2/CCN1/GBP1/RHOC/S100A10/CRIM1/EFEMP1/TGFA/ACTG2/IL1A/COL5A2/NABP1/ACKR3/ACKR2/MYLK/ARL14/ANXA3/PLAC8/INPP4B/ADRB2/CITED2/ADGRG6/SASH1/CAV2/CAV1/CPA4/PODXL/ZYX/ADAM9/ASPH/MATN2/FBXO32/EPPK1/S1PR3/GSN/CLIC3/DKK1/VCL/ANKRD1/ADM/MICAL2/AHNAK/PLAAT3/SERPINH1/SYTL2/PRSS23/TAGLN/GPRC5A/KRT80/KRT7/NUAK1/TNFRSF19/THBS1/ANXA2/TPM1/ALDH1A3/RHBDF1/TNFRSF12A/COTL1/PIEZO1/KRT17/JUP/CAVIN1/ACSF2/DSG2/CNN2/GADD45B/KCNN4/HMOX1/MYH9/A4GALT/DACH2/PLS3 | 74 |
| WANG_MLL_TARGETS | WANG_MLL_TARGETS | WANG_MLL_TARGETS | 62/1438 | 293/23056 | 0.2116041 | 3.392729 | 10.630821 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/S1PR1/PTPN22/TBX15/HSD11B1/AGT/EVA1A/DLX2/TWIST2/CCDC80/PARP14/SLCO2A1/MME/SPON2/SLIT2/CXCL3/PLAC8/VEGFC/DAB2/FOXD1/TGFBI/SH3RF2/ADAM19/FOXC1/RNF144B/B3GALT4/ARHGAP18/SASH1/THBS2/IL6/PDK4/ASB15/FABP4/GDF6/ANGPT1/RSPO2/COL14A1/S1PR3/ADM/ARHGDIB/AMIGO2/IGFBP6/GRIP1/POSTN/ZIC2/MMP14/NFATC4/PLEK2/BNC1/MMP2/MAF/KRT13/HOXB3/MRC2/ABCA9/KCNJ2/GATA6/CACNA1A/THBD/FOXS1/COL6A2/ARHGEF6 | 62 |
| QI_PLASMACYTOMA_UP | QI_PLASMACYTOMA_UP | QI_PLASMACYTOMA_UP | 57/1438 | 254/23056 | 0.2244094 | 3.598042 | 10.738183 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/CD53/S100A13/ACTG2/CAPG/DPP4/ITGA6/SP100/BHLHE40/ARAP2/PLAC8/MYO10/GPSM3/PSMB8/PSMB9/TNFAIP3/SCIN/ZYX/CLU/TRAF1/PTGS1/FAS/ANKRD1/PHLDA2/TRIM5/CD82/MMP10/CASP4/CASP1/UBASH3B/KLRD1/ARHGDIB/IGF1/FLT3/ALOX5AP/LCP1/TNFSF13B/NFKBIA/ZFP36L1/TNFAIP2/IL4R/IL21R/LAT/RRAD/CCL5/IFI35/CNN2/IL27RA/CD22/AXL/TGFB1/RELB/CD37/TGM2/IL2RB/RAC2/PDGFB | 57 |
| ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION | ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION | ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION | 39/1438 | 126/23056 | 0.3095238 | 4.962713 | 11.503502 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/GBP4/FCGR2A/IL1A/IL1B/IL36G/CXCL6/CXCL3/CXCL2/IL15/OSMR/CSF2/PLA2G7/TNFAIP3/SOD2/IL6/SERPINE1/SLC26A4/CEBPD/ST3GAL1/MAP3K8/TRIM5/ADM/SLC15A3/CASP4/RAB20/NFKBIA/TNFAIP2/THBS1/BCL2A1/MT1X/SOCS3/EBI3/TNFSF9/BCL3/RELB/IL4I1/MX1/USP18 | 39 |
| HAN_SATB1_TARGETS_UP | HAN_SATB1_TARGETS_UP | HAN_SATB1_TARGETS_UP | 77/1438 | 425/23056 | 0.1811765 | 2.904871 | 10.222625 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/CD34/TGFB2/LTBP1/EFEMP1/CYP26B1/SULT1C2/IL1B/BHLHE40/HRH1/TMEM158/LAMB2/WNT5A/MITF/FSTL1/FNDC3B/CLDN1/CXCL8/CXCL1/BMP3/SLC7A11/IL7R/OSMR/FST/GRAMD2B/TGFBI/CITED2/ADGRG6/IL6/GPNMB/INHBA/PDGFRL/TCIM/PLAT/ASPH/MATN2/CEMIP2/TNFSF15/PAEP/NACC2/SRGN/AIFM2/ZCCHC24/PAPSS2/ANKRD1/TCF7L2/PTPRE/ADM/CD82/SERPINH1/FZD4/MMP10/MMP1/CASP4/CASP1/NNMT/MPZL2/TPCN1/FLT1/TPM1/CA12/IL32/HOXB7/SERPINB8/MBP/ADGRE1/IL11/MYL9/TFAP2C/MX2/MX1/COL6A2/GGT1/LIF/APOL3/CELSR1/COL4A5 | 77 |
| GOBP_NEPHRON_DEVELOPMENT | GOBP_NEPHRON_DEVELOPMENT | GOBP_NEPHRON_DEVELOPMENT | 42/1438 | 146/23056 | 0.2876712 | 4.612342 | 11.292940 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/AGT/NID1/OSR1/LAMB2/WWTR1/HES1/NPNT/IRX2/ADAMTS16/GDNF/FOXD1/FOXC1/PDGFA/GLI3/PODXL/SHH/SULF1/ANGPT1/EXT1/TEK/NOTCH1/WT1/YAP1/EDNRB/BMP4/SIX1/SIX4/MYO1E/SOX8/SALL1/LHX1/HOXB7/ITGA3/NOG/PECAM1/SOX9/SERPINB7/BMP2/LIF/PDGFB/WNT7B | 42 |
| GOBP_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 71/1438 | 373/23056 | 0.1903485 | 3.051930 | 10.304359 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/HJV/TGFB2/LTBP1/CRIM1/BMP10/ITGB6/DLX1/COL3A1/PPARG/TGFBR2/WNT5A/FSTL1/ITGB5/WWTR1/VEPH1/HES1/KDR/BMP3/NPNT/LEF1/DAB2/FST/FOXD1/BMP6/HFE/RUNX2/CD109/PTPRK/CITED2/ITGB8/BMPER/INHBA/FZD1/CAV2/CAV1/ZYX/SHH/RBPMS/ZNF703/HTRA4/ADAM9/SULF1/GDF6/EXT1/CRB2/NOTCH1/ITGA8/DKK1/HTRA1/LRRC32/APOA1/BCL9L/LATS2/BMP4/DACT1/LTBP2/FOS/THBS1/FBN1/RBPMS2/SMAD6/MYOCD/ITGA3/NOG/GATA6/FSTL3/GDF15/TGFB1/PSG9/BMP2 | 71 |
| REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | 41/1438 | 140/23056 | 0.2928571 | 4.695490 | 11.311517 | 0.0000000 | 0.0000000 | 0.0000000 | HSPG2/CTSS/LAMC2/OPTC/LAMB3/NID1/COL3A1/COL5A2/FN1/COL6A3/COL7A1/COL8A1/SPP1/ADAMTS16/COL19A1/COL12A1/COL26A1/ADAM9/COL14A1/COL5A1/COL13A1/TLL2/HTRA1/CD44/MMP10/MMP1/MMP3/ADAMTS8/MMP14/FBN1/MMP2/CTRB1/ADAMTS18/COL1A1/ELANE/COL9A3/ADAMTS5/COL18A1/COL6A2/COL4A6/COL4A5 | 41 |
| GOBP_RESPIRATORY_SYSTEM_DEVELOPMENT | GOBP_RESPIRATORY_SYSTEM_DEVELOPMENT | GOBP_RESPIRATORY_SYSTEM_DEVELOPMENT | 50/1438 | 203/23056 | 0.2463054 | 3.949108 | 10.884823 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/EDN2/HSD11B1/ITGB6/COL3A1/THRB/TGFBR2/WNT5A/HEG1/MME/HES1/FGFRL1/KDR/LEF1/SLC7A11/FGF18/ADAMTS2/CCN2/PDGFA/GLI3/SHH/MSC/ZFPM2/RSPO2/EXT1/NOTCH1/SFTPD/FGFR2/WT1/PGR/YAP1/GLI1/MMP14/BMP4/SIX1/SIX4/ALDH1A2/ALDH1A3/CRISPLD2/FOXF1/MYOCD/ITGA3/NOG/SOX9/GATA6/KLF2/SIM2/LIF/WNT7B/CELSR1 | 50 |
| GOBP_POSITIVE_REGULATION_OF_MAPK_CASCADE | GOBP_POSITIVE_REGULATION_OF_MAPK_CASCADE | GOBP_POSITIVE_REGULATION_OF_MAPK_CASCADE | 84/1438 | 492/23056 | 0.1707317 | 2.737406 | 10.046855 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/PTPN22/PTPRC/TGFB2/TGFA/IL1A/IL1B/EPHA4/ACKR3/WNT5A/FGFR3/KDR/EPGN/NPNT/EGF/PDGFC/TLR3/F2RL1/SH3RF2/ADRB2/FGF18/EDN1/TPBG/TPD52L1/CCN2/SASH1/PDGFA/IL6/GPNMB/BMPER/CCL26/CD36/SEMA3A/CAV2/GPR37/ARHGEF5/FGF20/ADAM9/GDF6/ANGPT1/TEK/TRAF1/NOTCH1/JCAD/NRP1/FZD8/DKK1/FGFR2/TRIM5/CD44/PTPRJ/OR2AT4/FZD4/IGFBP6/IGF1/TNFRSF19/FLT3/FLT1/AJUBA/BMP4/THBS1/TNFAIP8L3/CSPG4/CCL5/CCR7/C1QTNF1/TNFRSF11A/ELANE/GADD45B/ICAM1/GDF15/TGFB1/APOE/C5AR1/IL11/ADRA1D/BMP2/DOK5/BIRC7/LIF/PDGFB/WNT7B/MID1/TENM1 | 84 |
| KOYAMA_SEMA3B_TARGETS_UP | KOYAMA_SEMA3B_TARGETS_UP | KOYAMA_SEMA3B_TARGETS_UP | 58/1438 | 266/23056 | 0.2180451 | 3.496000 | 10.560087 | 0.0000000 | 0.0000000 | 0.0000000 | CRABP2/LAMC2/NPAS2/AOX1/SP140L/SP100/CDCP1/SEMA3B/CCDC80/TM4SF18/ARL14/COX7B2/FGF5/LEF1/LVRN/TGFBI/ADRB2/SH3TC2/SPARC/RREB1/PSMB8/ITPR3/CRYBG1/TPD52L1/TMEM200A/CCN2/PDGFA/HOXA2/SERPINE1/PLAG1/CTHRC1/ANXA1/PLAU/RNLS/ARHGDIB/KRT8/KRT18/IGFBP6/GLIPR1/LTBP2/SERPINA1/CRIP1/THBS1/CCDC9B/PAQR5/LOXL1/EMILIN2/ST8SIA5/SERPINB8/GDF15/AXL/KCNN4/NECTIN2/SIRPA/MAP3K7CL/MID1/MSN/MAGEA10 | 58 |
| GRUETZMANN_PANCREATIC_CANCER_UP | GRUETZMANN_PANCREATIC_CANCER_UP | GRUETZMANN_PANCREATIC_CANCER_UP | 69/1438 | 359/23056 | 0.1922006 | 3.081625 | 10.252261 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP1/GBP2/CD53/ECM1/S100A10/S100A11/CRABP2/PTGS2/PTPRC/NID1/LTBP1/SULT1C2/KYNU/FAP/COL5A2/FN1/WNT5A/MYLK/ITGB5/ITGA2/SPARC/DOCK2/ITPR3/LAMA4/TNFAIP3/THBS2/SERPINE1/CAV2/CAV1/LOXL2/ADAM9/PLAT/ANXA1/KLF4/PTGS1/ALOX5/ANXA8/SRGN/PLAU/IFITM2/SERPINH1/BIRC3/CASP4/CASP1/NNMT/SCNN1A/EPS8/LUM/POSTN/LCP1/PYGL/SERPINA1/FBN1/IL4R/MMP2/FOXF1/KRT13/ITGA3/COL1A1/ITGB4/CNN1/EMP3/PRNP/MYL9/MX2/MYH9/MSN/GABRE | 69 |
| GOBP_TISSUE_MIGRATION | GOBP_TISSUE_MIGRATION | GOBP_TISSUE_MIGRATION | 70/1438 | 368/23056 | 0.1902174 | 3.049828 | 10.223448 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ZC3H12A/EDN2/S100A2/PTGS2/ATP2B4/TGFB2/AGT/BMP10/ACTG2/DPP4/FAP/NRP2/SP100/PPARG/TGFBR2/WNT5A/FSTL1/SLIT2/KDR/ANXA3/EGF/VEGFC/SEMA5A/ITGA2/PLK2/HBEGF/SPARC/FGF18/RREB1/ADTRP/EDN1/SASH1/BMPER/SEMA3A/EPHB4/MET/PTN/LOXL2/STC1/ADAM9/ANGPT1/HAS2/EPPK1/TEK/ANXA1/KLF4/NOTCH1/JCAD/NRP1/MMRN2/APOA1/PRKD1/BMP4/ACTC1/THBS1/CDH13/FOXF1/JUP/ITGA3/SOX9/TGFB1/APOE/RRAS/RIN2/HMOX1/MYH9/CARD10/PDGFB/SRPX2 | 70 |
| GOBP_MUSCLE_TISSUE_DEVELOPMENT | GOBP_MUSCLE_TISSUE_DEVELOPMENT | GOBP_MUSCLE_TISSUE_DEVELOPMENT | 74/1438 | 405/23056 | 0.1827160 | 2.929556 | 10.104048 | 0.0000000 | 0.0000000 | 0.0000000 | S1PR1/CASQ1/TGFB2/AGT/OSR1/BMP10/CYP26B1/VAMP5/XIRP2/COL3A1/DNER/RARB/TGFBR2/TNNC1/WNT5A/MYLK/HEG1/FOXL2/LEF1/MYOZ2/FOXC1/DSP/EDN1/RBM24/COL19A1/TBX18/GJA1/CITED2/MYL7/SEMA3C/CAV2/CAV1/SHH/FGF20/MSC/ZFPM2/NOTCH1/ITGA8/DKK1/MYOZ1/ANKRD1/TLL2/FGFR2/WT1/EFEMP2/YAP1/YBX3/WNT10B/ITGA7/GLI1/IGF1/BMP4/SIX1/SIX4/FOS/ACTC1/ALDH1A2/TPM1/HCN4/ALPK3/SOX8/NUPR1/MYLK3/MYOCD/NOG/SOX9/GATA6/DSG2/ALPK2/TGFB1/BMP2/JPH2/GATA5/RUNX1 | 74 |
| GOMF_SULFUR_COMPOUND_BINDING | GOMF_SULFUR_COMPOUND_BINDING | GOMF_SULFUR_COMPOUND_BINDING | 58/1438 | 269/23056 | 0.2156134 | 3.457011 | 10.454276 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/CCN1/LAMC2/CFH/PTPRC/LGR6/PRELP/CD34/SULT1C3/NRP2/FN1/SERPINE2/CCDC80/FSTL1/FGFRL1/SLIT2/SOD3/ADAMTS3/CXCL8/CXCL6/SEMA5A/ITGA2/FST/ACOT12/HBEGF/RSPO3/CCN2/THBS2/TMEM184A/GPNMB/PTN/TPK1/FGF20/RSPO2/CCN4/COL5A1/NRP1/COL13A1/FGFR2/SAA1/EFEMP2/ADAMTS8/ADAMTS15/SOAT2/POSTN/BMP4/LTBP2/SERPINA10/THBS1/FBN1/CRISPLD2/LIPG/ELANE/ADAMTSL5/APOE/ADAMTS5/PNPLA3/TENM1 | 58 |
| GOBP_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | GOBP_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | GOBP_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | 68/1438 | 354/23056 | 0.1920904 | 3.079858 | 10.170857 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/ZC3H12A/GFI1/VCAM1/PTPN22/PTGS2/NLRP3/IL1A/IL1B/IL36G/CASP8/CPS1/IRAK2/WNT5A/CD96/PLSCR4/CLDN1/SPON2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/TNIP3/PCSK1/CSF2/BMP6/EDN1/TNFAIP3/SASH1/SOD2/IL6/CD36/SERPINE1/ADAM9/IDO1/CD274/PDCD1LG2/NOTCH1/ANKRD1/FGFR2/TRIM5/ADM/CASP1/CARD16/KLRC4-KLRK1/EDNRB/NFKBIA/FOS/DIO2/BDKRB1/SMAD6/LOXL1/CD68/CCL5/CSF3/CCR7/TNFRSF11A/ELANE/ZFP36/AXL/TGFB1/C5AR1/SIRPA/THBD/DEFB124/CEBPB | 68 |
| WP_FOCAL_ADHESION | WP_FOCAL_ADHESION | WP_FOCAL_ADHESION | 49/1438 | 202/23056 | 0.2425743 | 3.889285 | 10.637492 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/LAMC2/LAMB3/ITGB6/ITGA6/ITGA4/COL5A2/FN1/LAMB2/MYLK/ITGB5/TXK/KDR/SPP1/EGF/PDGFC/VEGFC/ITGA2/LAMA4/LAMA2/THBS2/PDGFA/ITGB8/MYL7/CAV2/CAV1/MET/FLNC/ZYX/ITGA8/VCL/BIRC3/VWF/STYK1/ITGA5/ITGA7/IGF1/FLT1/THBS1/ITGA11/MYLK3/ITGA3/COL1A1/ITGB4/MYL9/COL6A2/RAC2/PDGFB/COL4A6 | 49 |
| GOCC_BASEMENT_MEMBRANE | GOCC_BASEMENT_MEMBRANE | GOCC_BASEMENT_MEMBRANE | 33/1438 | 95/23056 | 0.3473684 | 5.569490 | 11.510346 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/LAMC2/HMCN1/LAMB3/NID1/FN1/COL7A1/LAMB2/COL8A1/CCDC80/P3H2/AMTN/NPNT/TGFBI/SPARC/LAMA4/LAMA2/THBS2/LOXL2/COL5A1/MMRN2/EFEMP2/FREM2/NID2/FBN1/ANXA2/LOXL1/ITGB4/COL9A3/COL18A1/COL4A6/COL4A5 | 33 |
| PLASARI_TGFB1_TARGETS_10HR_UP | PLASARI_TGFB1_TARGETS_10HR_UP | PLASARI_TGFB1_TARGETS_10HR_UP | 48/1438 | 195/23056 | 0.2461538 | 3.946678 | 10.657532 | 0.0000000 | 0.0000000 | 0.0000000 | PRG4/PTGS2/NUAK2/WNT9A/GALNT3/BHLHE40/MGLL/EREG/PDGFC/F2RL1/HBEGF/FGF18/GFPT2/IER3/CCN2/TNFAIP3/PDGFA/IL6/INHBA/SERPINE1/TNFRSF11B/HAS2/FBXO32/PAPSS2/ANKRD1/MICAL2/FOSL1/ITGA5/TMCC3/NUAK1/FLT1/ALDH1A2/CSPG4/ALDH1A3/TNFRSF12A/CDYL2/CRISPLD2/MEOX1/FSTL3/GADD45B/CNN1/TGFB1/IL11/FOXS1/RUNX1/LIF/CARD10/PDGFB | 48 |
| LIANG_SILENCED_BY_METHYLATION_2 | LIANG_SILENCED_BY_METHYLATION_2 | LIANG_SILENCED_BY_METHYLATION_2 | 26/1438 | 58/23056 | 0.4482759 | 7.187377 | 12.168297 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/PTGS2/SP100/CXCL6/CXCL5/CXCL2/CSF2/HBEGF/NT5E/TNFAIP3/SOD2/IL6/INHBA/STC1/SAA1/MMP1/C1S/CCL5/KRT17/SERPINB2/C3/ICAM1/THBD/MX2/MX1/SSX2 | 26 |
| HINATA_NFKB_TARGETS_KERATINOCYTE_UP | HINATA_NFKB_TARGETS_KERATINOCYTE_UP | HINATA_NFKB_TARGETS_KERATINOCYTE_UP | 31/1438 | 84/23056 | 0.3690476 | 5.917081 | 11.643990 | 0.0000000 | 0.0000000 | 0.0000000 | GBP1/IL1B/ITGB6/FN1/WNT5A/CXCL8/CXCL6/CXCL3/IL15/IL7R/CSF2/TNFAIP3/SOD2/IL6/SERPINE1/PLAT/TRAF1/PLAU/SAA1/MMP1/ARHGDIB/KRT7/MMP14/NFKBIA/TNFAIP2/BCL2A1/IL32/CCL5/SERPINB2/ICAM1/BMP2 | 31 |
| ZHU_CMV_24_HR_DN | ZHU_CMV_24_HR_DN | ZHU_CMV_24_HR_DN | 31/1438 | 84/23056 | 0.3690476 | 5.917081 | 11.643990 | 0.0000000 | 0.0000000 | 0.0000000 | EFEMP1/COL3A1/COL5A2/ACKR3/LAMB2/MITF/MYLK/SULT1E1/CRHBP/TENT5A/LAMA4/THBS2/AHR/SERPINE1/TPM2/ANXA1/GAS1/MBL2/ADM/TAGLN/TNFRSF1A/C1R/POSTN/THBS1/ANPEP/COL1A1/CNN2/PTGIS/RUNX1/COL6A2/MN1 | 31 |
| HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | 54/1438 | 242/23056 | 0.2231405 | 3.577696 | 10.396639 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/S1PR1/MTMR11/CFH/IL1R1/IL1A/IL1B/NMI/SERPINE2/CDCP1/TM4SF1/MME/IL1RAP/CXCL3/EREG/ANXA3/SLC12A7/OSMR/FST/SERPINB1/TNFRSF21/NT5E/ADGRG6/SOD2/IL6/STC1/GSDMD/GAS1/PAPPA/TOR4A/IL15RA/PLAU/FOSL1/MMP3/CASP4/C1S/C1R/YBX3/PHLDA1/IRF9/PYGL/SERPINA1/EHD4/BCL2A1/CD68/CSF3/IFI35/WIPI1/SOCS3/MOCOS/KLF2/BCL3/PROCR/SAT1 | 54 |
| COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | COLINA_TARGETS_OF_4EBP1_AND_4EBP2 | 68/1438 | 359/23056 | 0.1894150 | 3.036963 | 10.032298 | 0.0000000 | 0.0000000 | 0.0000000 | FUCA1/TINAGL1/GBP2/GBP4/VCAM1/S100A13/PRRX1/OSR1/VIT/VAMP5/TFPI/BHLHE40/SHISA5/WNT5A/PLSCR2/TM4SF1/MME/RTP4/SOD3/CXCL6/ABCG2/NPR3/FST/FOXD1/FGF18/FOXC1/ID4/HLA-E/PSMB8/PSMB9/PERP/SASH1/SKAP2/HOXA2/PON3/FOXP2/PARP12/FABP4/CA13/RSPO2/TNFRSF11B/PPP1R3C/ACSL5/IFITM3/TRIM5/MMP3/NNMT/C1S/C1R/PHLDA1/POSTN/DNAJC15/IRF9/LTBP2/THBS1/MT1X/CCL5/IFI35/HOXB2/SLC16A3/C3/FXYD5/BLVRB/THBD/TGM2/SDC4/USP18/IL13RA1 | 68 |
| HELLER_SILENCED_BY_METHYLATION_UP | HELLER_SILENCED_BY_METHYLATION_UP | HELLER_SILENCED_BY_METHYLATION_UP | 59/1438 | 283/23056 | 0.2084806 | 3.342648 | 10.226909 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/TNFRSF4/TNFRSF9/TNFRSF1B/IFI44L/GBP1/VCAM1/CTSS/S100A13/LAMC2/CAPG/HNMT/KYNU/TFPI/BCL6/IL15/DDX60/SPARC/ADAM19/IER3/GPNMB/TRIP6/MSR1/CLU/DDX58/KLF4/PAEP/MAP3K8/MYOF/PHLDA2/BIRC3/KRT7/LCP1/IRF9/TNFAIP2/FBN1/IL32/NQO1/CCR7/PECAM1/SOCS3/TNFRSF11A/EBI3/ICAM1/APOE/C5AR1/PLA2G4C/SIRPA/MX1/DNMT3L/USP18/APOBEC3G/CELSR1/SAT1/SSX1/SSX2/IL13RA1/GPC4/MAGEA9 | 59 |
| GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN | 30/1438 | 79/23056 | 0.3797468 | 6.088625 | 11.684809 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/PTGS2/IKBKE/IL1B/BHLHE40/CXCL3/SPP1/RREB1/IER3/TAPBP/TNFAIP3/PDGFA/TRAF1/NFKB2/PTPRE/CD44/FOSL1/ITGA5/PHLDA1/NFKBIA/TNFAIP2/MT1X/CCL5/CSF3/SOCS3/GADD45B/TNFSF9/BCL3/CEBPB/RAC2 | 30 |
| VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN | VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN | 39/1438 | 134/23056 | 0.2910448 | 4.666431 | 10.978018 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/CFH/TGFB2/TGFA/NRP2/EPHA4/STAB1/EPHA3/FGFR3/CXCL8/CXCL1/CXCL5/EREG/EGF/PDGFC/F2RL1/CCN2/CD36/FZD1/EPHB4/PTN/EPHB6/ANGPT1/TNFSF15/PTGS1/NOTCH1/FZD8/C10orf55/FGFR2/PRSS23/IGF1/THBS1/ANPEP/TNFRSF12A/MMP2/CSF3/TGFB1/WNT7B | 39 |
| HENDRICKS_SMARCA4_TARGETS_UP | HENDRICKS_SMARCA4_TARGETS_UP | HENDRICKS_SMARCA4_TARGETS_UP | 25/1438 | 54/23056 | 0.4629630 | 7.422861 | 12.187001 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/SPOCD1/S100A2/PTPN7/ATP2B4/AGT/SERPINE2/TEC/CRYBG1/PERP/LOXL2/HKDC1/AHNAK/MMP1/ITGA5/TPM1/MFGE8/COTL1/KRT15/ITGA3/PSG5/PSG4/PSG9/EMP3/LGALS1 | 25 |
| TIAN_TNF_SIGNALING_VIA_NFKB | TIAN_TNF_SIGNALING_VIA_NFKB | TIAN_TNF_SIGNALING_VIA_NFKB | 18/1438 | 26/23056 | 0.6923077 | 11.100032 | 13.289747 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/PTGS2/CXCL8/CXCL1/CXCL3/CXCL2/PLK2/GFPT2/CCN2/TNFAIP3/IL6/TRAF1/NFKB2/NFKBIA/TNFAIP2/ZFP36/RELB/SDC4 | 18 |
| GOBP_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | GOBP_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | GOBP_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 75/1438 | 425/23056 | 0.1764706 | 2.829420 | 9.817711 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ZC3H12A/GBP1/PTPN22/IFI16/ILDR2/PTPRC/LAX1/TGFB2/NMI/DPP4/COL3A1/PPARG/CD96/PARP14/BCL6/SLIT2/TLR3/IL7R/IL31RA/PLK2/ADTRP/HFE/HLA-E/MICA/ADGRF5/TNFRSF21/TNFAIP3/AHR/GPNMB/HOXA7/INHBA/GLI3/SHH/IDO1/ANGPT1/CD274/PDCD1LG2/ANXA1/SFTPD/NLRP6/TSPAN32/PTPRJ/LRRC32/APOA1/UBASH3B/KLRD1/KLRC4-KLRK1/NCKAP1L/STAT6/LRFN5/BMP4/THBS1/FBN1/CYP19A1/IL4R/NLRC5/FOXF1/CD68/DHX58/MILR1/SOX9/RHBDF2/FSTL3/IL27RA/CD22/AXL/TGFB1/IL4I1/PRNP/SDC4/CEBPB/RUNX1/USP18/HMOX1 | 75 |
| SERVITJA_ISLET_HNF1A_TARGETS_UP | SERVITJA_ISLET_HNF1A_TARGETS_UP | SERVITJA_ISLET_HNF1A_TARGETS_UP | 44/1438 | 169/23056 | 0.2603550 | 4.174371 | 10.682204 | 0.0000000 | 0.0000000 | 0.0000000 | GBP4/VCAM1/CSF1/RHOC/PLA2G4A/TGFB2/EFEMP1/CAPG/COL3A1/COL5A2/SERPINE2/FST/SERPINB1/ID4/THBS2/PTN/CCN4/ANXA1/HTRA1/IFITM3/MS4A4A/SLC15A3/EFEMP2/SERPINH1/RAB38/C1S/ARHGDIB/ITGA7/POSTN/MMP14/TNFAIP2/FBN1/ANXA2/MAF/ABCC3/CNN2/BLVRB/APOE/PROCR/TGM2/COL18A1/LGALS1/MSN/BGN | 44 |
| HALLMARK_INTERFERON_ALPHA_RESPONSE | HALLMARK_INTERFERON_ALPHA_RESPONSE | HALLMARK_INTERFERON_ALPHA_RESPONSE | 33/1438 | 97/23056 | 0.3402062 | 5.454655 | 11.339077 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP2/GBP4/CSF1/NMI/CASP8/SP110/UBA7/PARP14/RTP4/IL15/DDX60/GMPR/HLA-C/PSMB8/PSMB9/TENT5A/SAMD9/SAMD9L/PARP12/IFITM2/IFITM3/TRIM5/CASP1/C1S/OASL/IRF9/IL4R/DHX58/IFI35/PROCR/MX1/USP18 | 33 |
| CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 53/1438 | 238/23056 | 0.2226891 | 3.570458 | 10.280507 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/ATP2B4/TGFBR2/SUSD5/HEG1/WWTR1/SEL1L3/SPP1/SLC7A11/IL15/PLK2/F2RL1/ELL2/PCSK1/ABLIM3/PXDC1/CAP2/MICB/SYNJ2/SERPINE1/FLNC/MEST/ZYX/CLU/PLAT/AQP3/NACC2/AKR1C3/FAS/PHLDA2/CD44/PLAAT3/SERPINH1/C1S/ITGA7/FOS/ALDH1A2/ANXA2/RRAD/NQO1/SLC16A3/SERPINB8/TNFSF9/GDF15/ZFP36/BLVRB/IL11/CEBPB/HMOX1/SAT1/SSX1/SSX2/ZNF185 | 53 |
| GOMF_EXTRACELLULAR_MATRIX_BINDING | GOMF_EXTRACELLULAR_MATRIX_BINDING | GOMF_EXTRACELLULAR_MATRIX_BINDING | 25/1438 | 55/23056 | 0.4545455 | 7.287900 | 12.041147 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/TINAGL1/CCN1/ECM1/CTSS/NID1/LRRC15/SLIT2/SPP1/ITGA2/TGFBI/SPARC/ADGRG6/SHH/PLEKHA2/ADAM9/ADAMTS15/ITGA7/THBS1/ITGA3/LYPD3/BCAM/ADAMTS5/LGALS1/BGN | 25 |
| SENESE_HDAC3_TARGETS_UP | SENESE_HDAC3_TARGETS_UP | SENESE_HDAC3_TARGETS_UP | 82/1438 | 495/23056 | 0.1656566 | 2.656035 | 9.606100 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/RHOC/IFI16/NPAS2/HNMT/KYNU/ITGA6/FN1/SERPINE2/TRPM8/TGFBR2/TMEM158/PHLDB2/SLC12A8/TM4SF18/TM4SF1/AADAC/ARL14/PLD1/BCL6/IL1RAP/CXCL8/CXCL5/CXCL3/SPP1/ARSJ/SLC7A11/PDGFC/GASK1B/VEGFC/IL7R/IQGAP2/F2RL1/HAPLN1/EDIL3/STING1/ADAM19/GFPT2/FOXC1/RSPO3/TNFAIP3/SOD2/ITGB8/FAM126A/PDK4/MET/AKR1B10/ASPH/TNFRSF11B/HAS2/B4GALT1/TNFSF15/PAPPA/TRAF1/AKR1C3/FZD8/PLAU/FAS/NFKB2/HTRA1/MICAL2/SAA1/CD44/BIRC3/MMP1/NNMT/UBASH3B/ROBO4/EMP1/HMGA2/NAV3/OASL/MMP14/NFKBIA/LTBP2/IL32/SLFN5/SLC14A1/BMP2/SAT1/SPANXB1/SPANXA1 | 82 |
| SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | 74/1438 | 421/23056 | 0.1757720 | 2.818219 | 9.710714 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/CSF1/S100A2/CRABP2/MR1/LAMB3/CNIH3/EFEMP1/CYP26B1/IL1R1/IL1B/GYPC/RPRM/COL6A3/FOXL2/FGFR3/SLC7A11/CSF2/HBEGF/SPARC/IER3/PSMB8/COL21A1/SYNJ2/SOD2/AHR/HOXA1/SAMD9/SERPINE1/STC1/ADAM28/PLAT/AQP3/OBP2B/PAEP/ZCCHC24/NFKB2/SAA1/EFEMP2/LRRC32/RAB38/BIRC3/KRT7/TESPA1/ITGA7/SLC7A7/PLEK2/SERPINA1/IL32/LAT/SALL1/TRPV2/CCL5/LHX1/DHX58/COPZ2/ABCC3/MRC2/KCNJ2/C3/ICAM1/CACNA1A/GDF15/CD22/GMFG/LYPD3/NPAS1/PROCR/TFAP2C/MX1/RAC2/SSX1/COL4A6/MAGEA9 | 74 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | 47/1438 | 194/23056 | 0.2422680 | 3.884375 | 10.405185 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/NEXN/IFI44L/MCOLN2/GBP1/PTGS2/FN1/SERPINE2/SP110/TM4SF1/RTP4/JCHAIN/CFI/IL15/INPP4B/DDX60/DDX60L/IL31RA/TSLP/FGF18/GMPR/TMEM200A/UST/HOXA3/HOXA7/SAMD9/SAMD9L/CAV1/RBPMS/IDO1/ANGPT1/DDX58/HBD/PLAAT4/SLC6A13/KRT18/METTL7B/OASL/FLT3/THBS1/HOXB3/MX2/MX1/USP18/APOL6/LGALS2/SLITRK4 | 47 |
| GOCC_CELL_SUBSTRATE_JUNCTION | GOCC_CELL_SUBSTRATE_JUNCTION | GOCC_CELL_SUBSTRATE_JUNCTION | 75/1438 | 431/23056 | 0.1740139 | 2.790031 | 9.675183 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/EPHA2/HSPG2/NEXN/HMCN1/PTPRC/ITGB6/DPP4/FAP/XIRP2/ITGA6/ITGA4/XIRP1/PHLDB2/ITGB5/MME/LPP/FGFR3/ARHGAP24/DAB2/ITGA2/GJA1/ITGB8/TNS3/FZD1/TRIP6/CAV2/CAV1/FLNC/ZYX/ADAM9/EPPK1/TEK/ANXA1/GSN/AIF1L/ITGA8/APBB1IP/NRP1/PLAU/VCL/CD44/AHNAK/LAYN/TNS2/ITGA5/FLT1/LCP1/TNFSF13B/MMP14/AJUBA/ACTC1/ITGA11/CSPG4/CDH13/GRB7/JUP/ITGA3/MRC2/ITGB4/CNN2/ICAM1/CNN1/NECTIN2/RRAS/PROCR/TGM2/SDC4/MYH9/RAC2/CDC42EP1/SMPX/MSN/STARD8/ZNF185 | 75 |
| GOBP_MUSCLE_CELL_PROLIFERATION | GOBP_MUSCLE_CELL_PROLIFERATION | GOBP_MUSCLE_CELL_PROLIFERATION | 52/1438 | 233/23056 | 0.2231760 | 3.578265 | 10.201720 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/S1PR1/PTGS2/TGFB2/AGT/BMP10/PPARG/TGFBR2/EREG/IL15/NPR3/ITGA2/HBEGF/FOXC1/EDN1/GJA1/TNFAIP3/CITED2/SOD2/IL6/SHH/FGF20/ZFPM2/ANGPT1/CCN4/NOTCH1/TCF7L2/FGFR2/EFEMP2/YAP1/GLI1/IGF1/BMP4/SIX1/THBS1/TPM1/RBPMS2/MMP2/CDH13/MYOCD/CCL5/NOG/GATA6/ELANE/CNN1/TGFB1/APOE/SIX5/BMP2/RUNX1/HMOX1/PDGFB | 52 |
| GOMF_LAMININ_BINDING | GOMF_LAMININ_BINDING | GOMF_LAMININ_BINDING | 18/1438 | 27/23056 | 0.6666667 | 10.688920 | 12.991938 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/TINAGL1/ECM1/CTSS/NID1/LRRC15/SLIT2/ITGA2/ADGRG6/SHH/PLEKHA2/ADAM9/ITGA7/THBS1/ITGA3/LYPD3/BCAM/LGALS1 | 18 |
| GOBP_MUSCLE_ORGAN_DEVELOPMENT | GOBP_MUSCLE_ORGAN_DEVELOPMENT | GOBP_MUSCLE_ORGAN_DEVELOPMENT | 64/1438 | 333/23056 | 0.1921922 | 3.081490 | 9.867746 | 0.0000000 | 0.0000000 | 0.0000000 | S1PR1/CASQ1/TGFB2/BMP10/CYP26B1/VAMP5/XIRP2/COL3A1/DNER/COL6A3/TNNC1/WNT5A/MYLK/HEG1/FOXL2/FGFRL1/LEF1/MYOZ2/HBEGF/FOXC1/DSP/RBM24/COL19A1/GJA1/LAMA2/CITED2/UTRN/FZD1/CAV2/CAV1/SHH/MSC/ZFPM2/NOTCH1/MYOZ1/ANKRD1/TLL2/FGFR2/WT1/ALX4/EFEMP2/CRYAB/TAGLN/YBX3/WNT10B/ITGA7/IGF1/BMP4/SIX1/SIX4/FOS/ACTC1/TPM1/ITGA11/SOX8/NUPR1/CTF1/MYOCD/SGCA/NOG/TGFB1/BMP2/JPH2/LIF | 64 |
| GOBP_GLAND_DEVELOPMENT | GOBP_GLAND_DEVELOPMENT | GOBP_GLAND_DEVELOPMENT | 75/1438 | 432/23056 | 0.1736111 | 2.783573 | 9.651666 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CSF1/ELF3/TGFB2/LBH/TGFA/CPS1/SERPINE2/TGFBR2/WNT5A/CLDN1/HES1/LEF1/EGF/ITGA2/PCSK1/FOXC1/RREB1/EDN1/ID4/DDR1/GJA1/TNFAIP3/CITED2/SOD2/PDGFA/IL6/HOXA3/GLI3/SEMA3C/SEMA3A/CAV1/MET/PTN/SHH/ZNF703/PLAG1/SULF1/EXT1/ANXA1/PTPN3/NOTCH1/NRP1/FGFR2/CCKBR/WT1/PGR/APOA1/STAT6/GLI1/BMP4/SIX1/SIX4/SERPINA10/CRIP1/CYP19A1/ALDH1A2/FOXB1/ALDH1A3/SALL1/MMP2/FOXF1/HOXB3/HOXB13/NOG/SOX9/GATA6/TNFRSF11A/TGFB1/BMP2/TGM2/CEBPB/HMOX1/WNT7B/MSN | 75 |
| ISSAEVA_MLL2_TARGETS | ISSAEVA_MLL2_TARGETS | ISSAEVA_MLL2_TARGETS | 26/1438 | 61/23056 | 0.4262295 | 6.833900 | 11.766882 | 0.0000000 | 0.0000000 | 0.0000000 | ELF3/LAMB3/SEMA3B/TNNC1/FSTL1/NPR3/HSPB3/NT5E/LOXL2/GSN/COL5A1/ANXA8L1/DKK1/PLAU/AHNAK/IGFBP6/CRIP1/SMAD6/LOXL1/CSPG4/KRT17/MEOX1/SLC16A5/AXL/C5AR1/COL9A3 | 26 |
| KANG_IMMORTALIZED_BY_TERT_UP | KANG_IMMORTALIZED_BY_TERT_UP | KANG_IMMORTALIZED_BY_TERT_UP | 31/1438 | 88/23056 | 0.3522727 | 5.648122 | 11.267084 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/LAMC2/TGFB2/ACTG2/PPARG/COL7A1/WNT5A/COL8A1/PDGFC/DOCK2/TFAP2A/SKAP2/CD36/TNFRSF11B/DKK1/NNMT/HPD/POSTN/CSPG4/IL21R/TRPV2/ITGA3/SERPINB2/C3/ICAM1/TGFB1/COL6A2/GGTLC2/PDGFB/COL4A6/BGN | 31 |
| KEGG_PATHWAYS_IN_CANCER | KEGG_PATHWAYS_IN_CANCER | KEGG_PATHWAYS_IN_CANCER | 63/1438 | 325/23056 | 0.1938462 | 3.108009 | 9.870954 | 0.0000000 | 0.0000000 | 0.0000000 | PTCH2/LAMC2/PTGS2/RASSF5/LAMB3/TGFB2/WNT9A/TGFA/ITGA6/CASP8/FN1/PPARG/RARB/TGFBR2/LAMB2/WNT5A/MITF/PLD1/FGFR3/CXCL8/FGF5/LEF1/EGF/VEGFC/ITGA2/FGF18/LAMA4/LAMA2/PDGFA/IL6/GLI3/FZD1/MET/SHH/FGF20/FZD6/TRAF1/FZD8/FAS/NFKB2/TCF7L2/FGFR2/FZD4/BIRC3/MMP1/WNT10B/GLI1/IGF1/FLT3/FOXO1/NFKBIA/BMP4/FOS/MMP2/JUP/ITGA3/TGFB1/BMP2/RUNX1/RAC2/PDGFB/WNT7B/COL4A6 | 63 |
| GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE | GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE | GOBP_REGULATION_OF_INFLAMMATORY_RESPONSE | 71/1438 | 397/23056 | 0.1788413 | 2.867431 | 9.679961 | 0.0000000 | 0.0000000 | 0.0000000 | C1QTNF12/TNFRSF1B/PTGS2/PTPRC/AGT/NLRP3/IL1R1/IL1B/NMI/PPARG/WNT5A/MGLL/SUCNR1/BCL6/IL15/TLR3/ADAMTS12/OSMR/ITGA2/PLK2/TSLP/STING1/HLA-E/GPSM3/PLA2G7/NT5E/TNFAIP3/IL6/SERPINE1/ZYX/IDO1/FABP4/CCN4/TEK/ANXA1/KLF4/ALOX5/NLRP6/SAA1/BIRC3/MMP3/CASP4/CASP1/APOA1/TNFRSF1A/IGF1/ALOX5AP/EDNRB/NFKBIA/LRFN5/CYP19A1/NUPR1/FOXF1/CCL5/CCR7/IFI35/RHBDF2/SOCS3/METRNL/TNFRSF11A/ELANE/CREB3L3/C3/ZFP36/APOE/SIRPA/PTGIS/CEBPB/USP18/GGT1/LGALS1 | 71 |
| JAEGER_METASTASIS_DN | JAEGER_METASTASIS_DN | JAEGER_METASTASIS_DN | 55/1438 | 259/23056 | 0.2123552 | 3.404772 | 10.037814 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/PDZK1IP1/S100A2/LAMC2/CFH/PRELP/LAMB3/CYP26B1/COL7A1/WNT5A/TM4SF1/FGFR3/ARAP2/CDS1/IRX4/FST/F2RL1/DSP/ITPR3/CRYBG1/GJA1/TPD52L1/PERP/PTPRZ1/AKR1B10/EPHB6/MATN2/EPPK1/AQP3/KLF4/PTGS1/CLIC3/ANXA8/FGFR2/BBOX1/EHF/AHNAK/MPZL2/SCNN1A/DIO2/CA12/MAF/KRT15/KRT19/KRT17/JUP/ABCC3/ITGB4/LYPD3/THBD/TFAP2C/ITM2A/COL4A6/GABRE/ZNF185 | 55 |
| LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP | LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_UP | 30/1438 | 83/23056 | 0.3614458 | 5.795197 | 11.287323 | 0.0000000 | 0.0000000 | 0.0000000 | PLA2G4A/CYP26B1/EVA1A/HRH1/TMEM158/FOXL2/P3H2/CXCL8/FOXD1/HAPLN1/FOXC1/SOD2/IL6/FAM126A/TNFRSF11B/HAS2/HRCT1/COL27A1/ADM/YBX3/CSPG4/BCL2A1/TNFRSF12A/ICAM1/PRNP/BMP2/CEBPB/COL9A3/HMOX1/MSN | 30 |
| GOBP_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE | GOBP_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE | GOBP_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE | 41/1438 | 153/23056 | 0.2679739 | 4.296527 | 10.551407 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/CSF1/AGT/TGFBR2/WNT5A/SLIT2/KDR/NPNT/LEF1/EGF/ADAMTS16/GDNF/FOXD1/EDN1/DDR1/GLI3/MET/SHH/RSPO2/EXT1/NOTCH1/NRP1/FGFR2/WT1/PGR/YAP1/MMP14/NFATC4/BMP4/SIX1/SIX4/SOX8/SALL1/FOXF1/LHX1/HOXB7/NOG/SOX9/BMP2/CELSR1 | 41 |
| MANALO_HYPOXIA_UP | MANALO_HYPOXIA_UP | MANALO_HYPOXIA_UP | 48/1438 | 205/23056 | 0.2341463 | 3.754157 | 10.215680 | 0.0000000 | 0.0000000 | 0.0000000 | SPSB1/NPAS2/GYPC/ACKR3/BHLHE40/PPARG/FNDC3B/BCL6/HES1/VEGFC/RAI14/TGFBI/EDN1/HLA-E/IER3/B3GALT4/TENT5A/TNFAIP3/GPNMB/INHBA/SERPINE1/LOXL2/STC1/TCIM/PTGS1/COL5A1/HTRA1/ADM/LRRC32/VWF/NUAK1/NFATC4/TPM1/SMAD6/ALPK3/MMP2/MYH13/GADD45B/CYP4F11/AXL/RRAS/PTGIS/BACE2/COL18A1/MN1/PDGFB/ITM2A/BGN | 48 |
| MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | MCBRYAN_PUBERTAL_TGFB1_TARGETS_UP | 43/1438 | 168/23056 | 0.2559524 | 4.103782 | 10.413486 | 0.0000000 | 0.0000000 | 0.0000000 | HSPG2/CCN1/ECM1/PTPN14/CRIM1/ACTG2/CAPG/GALNT3/FN1/BHLHE40/COL7A1/WNT5A/COL8A1/HES1/KDR/PDGFC/IER3/GJA1/PTPRK/UTRN/CLU/PLAT/FZD6/HAS2/TPM2/CEMIP2/GSN/HTRA1/FZD4/TAGLN/KRT18/MMP14/MFGE8/MMP2/COTL1/SOX9/LIPG/CNN1/CDC42EP5/SIRPA/TGM2/RUNX1/IL13RA1 | 43 |
| GOMF_GROWTH_FACTOR_BINDING | GOMF_GROWTH_FACTOR_BINDING | GOMF_GROWTH_FACTOR_BINDING | 39/1438 | 140/23056 | 0.2785714 | 4.466442 | 10.610424 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CCN1/S100A13/LTBP1/CRIM1/IL1R1/ITGA6/COL3A1/NRP2/TGFBR2/FGFRL1/FGFR3/KDR/NKD2/OSMR/CD109/CCN2/PDGFA/CD36/HTRA4/CCN4/COL5A1/NRP1/FGFR2/HTRA1/LRRC32/IGFBP6/FLT3/FLT1/LTBP2/THBS1/RHBDF1/HAP1/COL1A1/ITGB4/RHBDF2/IL2RB/PDGFB/SRPX2 | 39 |
| CERVERA_SDHB_TARGETS_2 | CERVERA_SDHB_TARGETS_2 | CERVERA_SDHB_TARGETS_2 | 35/1438 | 114/23056 | 0.3070175 | 4.922529 | 10.828223 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/PRRX1/TGFB2/SULT1C2/NMI/GALNT3/SERPINE2/COL7A1/VGLL3/P3H2/IL1RAP/CXCL8/CXCL5/TFAP2A/MICB/NT5E/CRYBG1/GJA1/MOXD1/CADPS2/CSGALNACT1/MATN2/LRATD2/HKDC1/MICAL2/SYT12/PRSS23/APOA1/UBASH3B/METTL7B/NUAK1/TNFRSF19/LTBP2/FSTL3/GPC4 | 35 |
| GOCC_ACTIN_CYTOSKELETON | GOCC_ACTIN_CYTOSKELETON | GOCC_ACTIN_CYTOSKELETON | 81/1438 | 494/23056 | 0.1639676 | 2.628955 | 9.439261 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/HSPB7/NEXN/GBP1/VCAM1/LMOD1/ACTG2/CAPG/XIRP2/MPP4/CATIP/MLPH/XIRP1/ACKR2/TNNC1/EPHA3/MYLK/LPP/ARSJ/MYOZ2/MYO10/ACTBL2/IQGAP2/ABLIM3/CLIC5/FILIP1/UTRN/MICALL2/SCIN/WIPF3/MYL7/TRIP6/LMOD2/ZYX/ARHGEF5/PDLIM2/ADCY8/CD274/TEK/DDX58/TPM2/ANXA1/GSN/AIF1L/MYOZ1/SYNPO2L/VCL/BAG3/C10orf90/MICAL2/AHNAK/EHBP1L1/CRYAB/RND1/FLT1/LCP1/ACTC1/BMF/CGNL1/MYO1E/TPM1/MYLK3/COTL1/MYH13/MYH8/MYH4/MYH1/MYH2/KRT19/HAP1/JUP/MYL4/LLGL2/CNN2/AXL/MYL9/GAS2L1/MYH9/RAC2/PLS3/ZNF185 | 81 |
| TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | 48/1438 | 206/23056 | 0.2330097 | 3.735933 | 10.173028 | 0.0000000 | 0.0000000 | 0.0000000 | CYP4X1/PDZK1IP1/LAMC2/ELF3/LAMB3/TGFA/ACTG2/IQCA1/CMTM8/MYLK/TM4SF1/JCHAIN/CFI/GRAMD2B/ID4/SOD2/ITGB8/HOXA3/TRIP6/CAV2/MET/PTN/RBPMS/TCIM/FBXO32/ANXA1/SAA1/BBOX1/EHF/CRYAB/TAGLN/YBX3/BHLHE41/KRT7/FOS/SERPINA1/CCDC9B/ANPEP/ALDH1A3/RRAD/KRT15/KRT17/SOX9/ITGB4/CNN1/ADAMTS5/MID1/GABRE | 48 |
| BROWNE_HCMV_INFECTION_48HR_DN | BROWNE_HCMV_INFECTION_48HR_DN | BROWNE_HCMV_INFECTION_48HR_DN | 80/1438 | 485/23056 | 0.1649485 | 2.644681 | 9.441292 | 0.0000000 | 0.0000000 | 0.0000000 | HSPG2/MTMR11/S100A13/CRABP2/LAMC2/CFH/LMOD1/EFEMP1/DPP4/FAP/ITGA4/AOX1/FN1/PPARG/UBA7/SLCO2A1/LPP/CXCL6/SPP1/RAI14/OSMR/TGFBI/ADAMTS2/PSMB8/RCAN2/PTP4A1/ROS1/GJA1/LAMA2/MOXD1/THBS2/INHBA/MDFIC/ZYX/PDGFRL/LOXL2/PNOC/RBPMS/ASPH/SULF1/MSC/MATN2/HAS2/JCAD/IFITM2/SLC22A18/MICAL2/EFEMP2/SERPINH1/MMP3/TAGLN/C3AR1/IGFBP6/POSTN/SLC7A7/NFATC4/SIX1/LTBP2/FBLN5/EPB42/ANXA2/CA12/CAVIN1/IFI35/ITGA3/WIPI1/ABCA6/SLC16A5/SOCS3/SERPINB7/CACNA1A/HSPB6/ZFP36/PSG4/EMP3/MYL9/COL6A2/FRMPD4/SSX2/MAGEA10 | 80 |
| WP_NUCLEAR_RECEPTORS_METAPATHWAY | WP_NUCLEAR_RECEPTORS_METAPATHWAY | WP_NUCLEAR_RECEPTORS_METAPATHWAY | 62/1438 | 321/23056 | 0.1931464 | 3.096790 | 9.756953 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/EDN2/PTGS2/TGFB2/TGFA/IL1B/CAVIN2/DNER/ACKR3/BHLHE40/TGFBR2/EPHA3/HES1/SOD3/UGT2B7/SLC7A11/AHRR/PLK2/HBEGF/SLC6A7/CAP2/ADGRF4/TNFAIP3/AHR/PDK4/PTGR1/SRGN/ANKRD1/MYOF/NFKB2/SLC5A12/PRRG4/SLCO2B1/BIRC3/APOC3/APOA1/SLC6A13/SCNN1A/SLC2A14/AMIGO2/NAV3/ALOX5AP/FOXO1/DNAJC15/ZIC2/SERPINA1/MFGE8/CES1/NQO1/ABCC3/SERPINB2/GADD45B/BLVRB/TGFB1/SLC6A16/IL11/THBD/GGTLC2/GGT1/HMOX1/PDGFB/SRPX2 | 62 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | 45/1438 | 184/23056 | 0.2445652 | 3.921207 | 10.260616 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/S1PR1/RHOC/ECM1/IFI16/NID1/TFPI/COL3A1/TGFBR2/FSTL1/TM4SF1/CXCL8/SLC7A11/DAB2/F2RL1/CRHBP/SPARC/DDR1/AHR/RBPMS/PLAT/DDX58/GSN/NFKB2/TCF7L2/TRIM5/PRSS23/EMP1/EPS8/AMIGO2/DRAM1/IRF9/ALDH1A2/ANXA2/NQO1/JUP/SERPINB2/GDF15/PSG9/APOE/RRAS/PROCR/RUNX1/HMOX1/IL13RA1 | 45 |
| HALLMARK_APICAL_JUNCTION | HALLMARK_APICAL_JUNCTION | HALLMARK_APICAL_JUNCTION | 47/1438 | 200/23056 | 0.2350000 | 3.767844 | 10.139366 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/NEXN/VCAM1/ITGA10/LAMC2/PTPRC/CD34/LAMB3/ACTG2/SLIT2/ITGA2/TGFBI/SKAP2/FLNC/ZYX/ADAM9/TNFRSF11B/CD274/B4GALT1/TRAF1/VCL/LAYN/MPZL2/VWF/AMIGO2/ACTC1/FBN1/CLDN6/MMP2/CDH15/CLDN7/GRB7/JUP/ITGA3/PECAM1/ITGB4/CNN2/ICAM1/NECTIN2/RRAS/SIRPA/MYL9/ADAMTS5/MYH9/RAC2/MSN/ARHGEF6 | 47 |
| GOBP_CELL_CHEMOTAXIS | GOBP_CELL_CHEMOTAXIS | GOBP_CELL_CHEMOTAXIS | 61/1438 | 315/23056 | 0.1936508 | 3.104877 | 9.701333 | 0.0000000 | 0.0000000 | 0.0000000 | ARHGEF16/EPHA2/EDN2/VCAM1/S1PR1/CSF1/TGFB2/IL1B/DPP4/ACKR3/HRH1/ACKR2/CCR3/WNT5A/SLIT2/KDR/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/LEF1/VEGFC/SEMA5A/F2RL1/HBEGF/FGF18/EDN1/GPSM3/PLA2G7/TPBG/IL6/CCL26/SERPINE1/MET/PTN/ARHGEF5/RARRES2/ANXA1/NOTCH1/NRP1/ALOX5/SFTPD/SAA1/C3AR1/KLRC4-KLRK1/NCKAP1L/FLT1/EDNRB/PRKD1/THBS1/CYP19A1/CCL5/CCR7/TNFRSF11A/TNFSF14/C5AR1/DEFB124/RAC2/PDGFB | 61 |
| GOBP_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | GOBP_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | GOBP_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 61/1438 | 315/23056 | 0.1936508 | 3.104877 | 9.701333 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/HJV/ATP2B4/AGT/LTBP1/CRIM1/IL1B/DLX1/PPARG/WNT5A/FSTL1/VEPH1/HES1/SLIT2/KDR/ADAMTS3/NPNT/VEGFC/ADAMTS12/DAB2/FST/FOXD1/FGF18/RUNX2/CD109/CITED2/FAM20C/BMPER/FZD1/CAV2/CAV1/TSPAN12/ZNF703/HTRA4/SULF1/CRB2/NOTCH1/ITGA8/JCAD/DKK1/MMRN2/HHEX/HTRA1/CREB3L1/FZD4/BCL9L/ITGA5/LATS2/BMP4/THBS1/FBN1/RBPMS2/SMAD6/MYOCD/ITGA3/NOG/GATA6/FSTL3/TGFB1/BMP2/DOK5 | 61 |
| GOBP_REGULATION_OF_T_CELL_ACTIVATION | GOBP_REGULATION_OF_T_CELL_ACTIVATION | GOBP_REGULATION_OF_T_CELL_ACTIVATION | 64/1438 | 342/23056 | 0.1871345 | 3.000399 | 9.612515 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/RUNX3/ZC3H12A/VCAM1/PTPN22/ILDR2/TNFSF18/PTPRC/LAX1/ITPKB/NLRP3/CYP26B1/IL1A/IL1B/DPP4/TGFBR2/BCL6/HES1/LEF1/IL15/IL7R/HFE/HLA-E/TNFRSF21/VNN1/IL6/GPNMB/GLI3/CAV1/SHH/IDO1/CD274/PDCD1LG2/ANXA1/MAP3K8/SFTPD/LRRC32/KLRC4-KLRK1/NCKAP1L/TESPA1/IGF1/TNFSF13B/BMP4/IL4R/LAT/CCL5/CCR7/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/PSG9/IL4I1/SIRPG/SIRPA/PRNP/SDC4/CEBPB/RUNX1/ICOSLG/RAC2/LGALS1 | 64 |
| GOBP_CHONDROCYTE_DIFFERENTIATION | GOBP_CHONDROCYTE_DIFFERENTIATION | GOBP_CHONDROCYTE_DIFFERENTIATION | 34/1438 | 110/23056 | 0.3090909 | 4.955772 | 10.725767 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ECM1/WNT9A/OSR1/EFEMP1/COL3A1/RARB/TGFBR2/FGFR3/NKX3-2/ADAMTS12/TGFBI/FGF18/BMP6/RUNX2/CCN2/SCIN/GLI3/LOXL2/SULF1/GDF6/TRPS1/EXT1/CCN4/COL27A1/SERPINH1/WNT10B/HMGA2/BMP4/MAF/SOX9/TGFB1/BMP2/RUNX1 | 34 |
| GOBP_GLAND_MORPHOGENESIS | GOBP_GLAND_MORPHOGENESIS | GOBP_GLAND_MORPHOGENESIS | 36/1438 | 123/23056 | 0.2926829 | 4.692697 | 10.590586 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CSF1/ELF3/TGFB2/TGFA/TGFBR2/WNT5A/ID4/DDR1/TNFAIP3/PDGFA/IL6/GLI3/SEMA3C/SEMA3A/CAV1/PTN/SHH/PLAG1/SULF1/NOTCH1/NRP1/FGFR2/PGR/STAT6/GLI1/BMP4/CRIP1/MMP2/HOXB13/NOG/SOX9/TGFB1/TGM2/CEBPB/MSN | 36 |
| GOCC_COLLAGEN_TRIMER | GOCC_COLLAGEN_TRIMER | GOCC_COLLAGEN_TRIMER | 30/1438 | 86/23056 | 0.3488372 | 5.593039 | 11.005839 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/COL21A1/COL19A1/COL12A1/COL26A1/MSR1/CTHRC1/COLEC10/COL14A1/COL27A1/COL5A1/MBL2/COL13A1/SFTPD/LUM/GLDN/C1QTNF8/COL1A1/C1QTNF1/COLEC12/EMILIN2/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 30 |
| GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION | 58/1438 | 291/23056 | 0.1993127 | 3.195656 | 9.721456 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/VCAM1/PTPN22/PTPRC/ITPKB/NLRP3/IL1A/IL1B/DPP4/ITGA4/TGFBR2/WNT5A/BCL6/HES1/LEF1/IL15/MYO10/IL7R/ADAM19/HLA-E/VNN1/CITED2/IL6/GLI3/CAV1/PODXL/SHH/HAS2/CD274/PDCD1LG2/ANXA1/MAP3K8/ALOX5/CD44/KLRC4-KLRK1/NCKAP1L/TESPA1/IGF1/TNFSF13B/IL4R/PIEZO1/CCL5/CCR7/EMILIN2/FSTL3/ELANE/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/IL4I1/SIRPG/SIRPA/RUNX1/ICOSLG/LGALS1 | 58 |
| FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | 76/1438 | 453/23056 | 0.1677704 | 2.689927 | 9.368892 | 0.0000000 | 0.0000000 | 0.0000000 | FUCA1/IFI44L/GBP1/GBP2/IFI16/ITPKB/VAMP5/HNMT/NMI/SP110/SP100/HRH1/TGFBR2/STAB1/HEG1/SUCNR1/TMEM212/BCL6/ARAP2/RBM47/SLC12A7/TGFBI/SLC22A23/TRIM38/TENT5A/CITED2/ZC3H12D/GPNMB/CD36/SAMD9/SAMD9L/PDGFRL/PLEKHA2/IDO1/CEBPD/PARP10/DDX58/KLF4/IL15RA/MAP3K8/FAS/IFITM2/IFITM3/TRIM5/MS4A4A/MAML2/C1S/C3AR1/CPM/OASL/SLC46A3/NUPR1/CES1/MAF/SLFN5/DHX58/PECAM1/RHBDF2/SOCS3/MBP/GADD45B/ADGRE1/KLF2/ZFP36/BLVRB/CD37/FPR1/RIN2/MX2/MX1/USP18/HMOX1/APOL3/APOBEC3A/APOBEC3G/SAT1 | 76 |
| GOBP_REGULATION_OF_VASCULATURE_DEVELOPMENT | GOBP_REGULATION_OF_VASCULATURE_DEVELOPMENT | GOBP_REGULATION_OF_VASCULATURE_DEVELOPMENT | 65/1438 | 353/23056 | 0.1841360 | 2.952322 | 9.533480 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/HSPG2/ZC3H12A/TIE1/ECM1/ATP2B4/CD34/TGFB2/AGT/IL1A/IL1B/SP100/PPARG/TGFBR2/CCR3/STAB1/WNT5A/KDR/CXCL8/ANXA3/VEGFC/TLR3/SEMA5A/PLK2/SPARC/FGF18/FOXC1/TNFAIP3/SASH1/THBS2/ITGB8/IL6/GPNMB/AQP1/BMPER/SERPINE1/TSPAN12/SULF1/TEK/CEMIP2/KLF4/JCAD/NRP1/ALOX5/HHEX/ADM/CREB3L1/C3AR1/ITGA5/HMGA2/FLT1/PRKD1/THBS1/JUP/EMILIN2/GATA6/C3/KLF2/HSPB6/C5AR1/RRAS/PTGIS/RUNX1/HMOX1/CYSLTR1 | 65 |
| GOBP_NEPHRON_EPITHELIUM_DEVELOPMENT | GOBP_NEPHRON_EPITHELIUM_DEVELOPMENT | GOBP_NEPHRON_EPITHELIUM_DEVELOPMENT | 34/1438 | 111/23056 | 0.3063063 | 4.911125 | 10.653037 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/AGT/OSR1/LAMB2/WWTR1/HES1/NPNT/IRX2/ADAMTS16/GDNF/FOXD1/FOXC1/GLI3/PODXL/SHH/EXT1/NOTCH1/WT1/YAP1/EDNRB/BMP4/SIX1/SIX4/MYO1E/SOX8/SALL1/LHX1/HOXB7/NOG/PECAM1/SOX9/BMP2/LIF/WNT7B | 34 |
| HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | 51/1438 | 235/23056 | 0.2170213 | 3.479585 | 9.853710 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/CCN1/CD53/CTSS/S100A10/S100A11/S100A13/CRABP2/IFI16/FCGR2A/PTPRC/IKBKE/EFEMP1/GYPC/COL3A1/COL5A2/CXCL1/IL7R/DAB2/PPIC/IER3/DDR1/ITPR3/CCN2/GPNMB/AQP1/ADAM9/TPM2/ANXA1/IL15RA/SRGN/TAGLN/C3AR1/ARHGDIB/GLIPR1/LUM/ALOX5AP/POSTN/LCP1/LTBP2/FBN1/BCL2A1/CCL5/CCR7/CD37/RIN2/PROCR/COL6A2/IL2RB/LGALS1/MSN | 51 |
| GOBP_MESENCHYME_DEVELOPMENT | GOBP_MESENCHYME_DEVELOPMENT | GOBP_MESENCHYME_DEVELOPMENT | 59/1438 | 302/23056 | 0.1953642 | 3.132349 | 9.620267 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/OSR1/ACTG2/IL1B/NRP2/FN1/EPHA4/TGFBR2/SEMA3B/WNT5A/EPHA3/PHLDB2/WWTR1/HES1/LEF1/SEMA5A/GDNF/DAB2/FOXD1/FOXC1/EDN1/RBM24/CITED2/IL6/SEMA3C/SEMA3A/SEMA3D/SHH/LOXL2/ZNF703/ZFPM2/EXT1/HAS2/CRB2/NOTCH1/NRP1/TCF7L2/FGFR2/WT1/YAP1/BCL9L/HMGA2/EDNRB/BMP4/SIX1/SIX4/ZFP36L1/ACTC1/ALDH1A2/SOX8/FOXF1/MEOX1/COL1A1/NOG/SOX9/SEMA6B/TGFB1/BMP2/GATA5 | 59 |
| KATSANOU_ELAVL1_TARGETS_UP | KATSANOU_ELAVL1_TARGETS_UP | KATSANOU_ELAVL1_TARGETS_UP | 43/1438 | 174/23056 | 0.2471264 | 3.962272 | 10.115953 | 0.0000000 | 0.0000000 | 0.0000000 | C1QTNF12/SPSB1/DHRS3/CTSS/HMCN1/EPHA4/DNER/RARB/TNNC1/SPON2/FOXD1/FOXC1/DSP/ADGRF5/VNN1/MEST/PLEKHA2/FZD6/AIF1L/FAS/ANKRD1/TRIM5/FIBIN/SYTL2/C3AR1/IGF1/SLC7A7/BMP4/ALDH1A3/ITPRIPL2/NUPR1/MMP2/LPCAT2/FOXF1/ITGA3/MYOM1/GDF15/APOE/TGM2/ADAMTS5/MAP3K7CL/PDGFB/SAT1 | 43 |
| MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | 48/1438 | 212/23056 | 0.2264151 | 3.630199 | 9.922583 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/CCN1/HSD11B1/PTPN14/EFEMP1/FN1/MLPH/CDCP1/COL8A1/JCHAIN/SPP1/IRX2/PLK2/DSP/GMPR/ID4/GJA1/PERP/FZD1/PTN/CLU/TRPS1/HAS2/FBXO32/CEMIP2/GAS1/GSN/ADM/EHF/KRT7/KRT8/KRT18/PHLDA1/MMP14/SERPINA1/CSPG4/MFGE8/TNFRSF12A/KRT19/ACSF2/ABCC3/MRC2/SOX9/LIPG/CNN1/TFAP2C/RUNX1/SRPX2 | 48 |
| GOBP_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 55/1438 | 269/23056 | 0.2044610 | 3.278200 | 9.693458 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/HJV/TGFB2/LTBP1/CRIM1/BMP10/DLX1/PPARG/TGFBR2/WNT5A/FSTL1/VEPH1/HES1/KDR/BMP3/NPNT/DAB2/FST/FOXD1/BMP6/HFE/CD109/CITED2/BMPER/INHBA/FZD1/CAV2/CAV1/SHH/RBPMS/ZNF703/HTRA4/SULF1/GDF6/CRB2/NOTCH1/ITGA8/DKK1/HTRA1/BCL9L/LATS2/BMP4/DACT1/THBS1/FBN1/RBPMS2/SMAD6/MYOCD/ITGA3/NOG/GATA6/FSTL3/GDF15/TGFB1/BMP2 | 55 |
| GU_PDEF_TARGETS_UP | GU_PDEF_TARGETS_UP | GU_PDEF_TARGETS_UP | 27/1438 | 71/23056 | 0.3802817 | 6.097201 | 11.094121 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/ITGA6/COL5A2/FN1/COL6A3/LAMB2/WNT5A/LEF1/TGFBI/CCN2/FZD1/SERPINE1/COL5A1/FZD8/COL13A1/FZD4/ITGA5/SERPINA1/ITGA3/COL1A1/SERPINB7/TGFB1/BMP2/COL6A2/RAC2/COL4A6/COL4A5 | 27 |
| PEDRIOLI_MIR31_TARGETS_DN | PEDRIOLI_MIR31_TARGETS_DN | PEDRIOLI_MIR31_TARGETS_DN | 71/1438 | 412/23056 | 0.1723301 | 2.763034 | 9.312943 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF4/GBP2/VCAM1/PLA2G4A/NID1/NPAS2/SERPINE2/ACKR3/IRAK2/TGFBR2/AADAC/CXCL8/CXCL2/ANXA3/PLAC8/SPP1/ABCG2/SLC7A11/CTSO/TSLP/SH3TC2/PSORS1C1/LAMA2/TNFAIP3/RAET1E/SOD2/MAFK/SAMD9/SAMD9L/PDK4/SLC26A4/EPHB6/DOK2/STC1/CLU/PNOC/ADAM32/AIF1L/NRP1/NFKB2/OR6A2/RAB38/BIRC3/MMP10/VWF/EMP1/BHLHE41/WNT10B/CPM/LATS2/SLC46A3/EDNRB/CYP46A1/IL32/RRAD/NQO1/CDH13/FMNL1/ITGB4/SLC16A3/EMILIN2/MYOM1/DSG2/TNFSF14/ICAM1/PLVAP/RELB/PLA2G4C/MAP3K7CL/MX1/GGTLC2 | 71 |
| REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES | REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES | REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES | 25/1438 | 61/23056 | 0.4098361 | 6.571057 | 11.236733 | 0.0000000 | 0.0000000 | 0.0000000 | CTSS/LAMC2/LAMB3/ITGA6/COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/COL12A1/LOXL2/COL14A1/COL27A1/COL5A1/TLL2/LOXL4/MMP3/LOXL1/COL1A1/ITGB4/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 25 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | 44/1438 | 184/23056 | 0.2391304 | 3.834069 | 9.954547 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP3/GBP1/S100A10/IFI16/PTGS2/PLA2G4A/SP110/PARP14/SLC12A8/TXK/JCHAIN/INPP4B/DDX60/DDX60L/CRHBP/TSLP/FGF18/GMPR/VNN1/AHR/ITGB8/HOXA3/HOXA7/PDE1C/SAMD9/SAMD9L/CAV1/PARP12/RBPMS/IDO1/ANGPT1/PARP10/DDX58/PTGS1/PRSS23/OASL/IRF9/ACSM3/IFI35/HOXB3/MX2/MX1/USP18 | 44 |
| PETROVA_PROX1_TARGETS_DN | PETROVA_PROX1_TARGETS_DN | PETROVA_PROX1_TARGETS_DN | 24/1438 | 56/23056 | 0.4285714 | 6.871448 | 11.345656 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/PLA2G4A/FAP/BMP6/CAP2/TNFRSF21/ADGRG6/IL6/SERPINE1/NRP1/SRGN/PLAU/NNMT/ARHGDIB/KRT7/ITGA5/NUAK1/MMP14/LTBP2/IL32/AXL/EMP3/PRNP/PROCR | 24 |
| GOBP_ENDOTHELIAL_CELL_MIGRATION | GOBP_ENDOTHELIAL_CELL_MIGRATION | GOBP_ENDOTHELIAL_CELL_MIGRATION | 56/1438 | 281/23056 | 0.1992883 | 3.195264 | 9.549157 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ZC3H12A/EDN2/S100A2/PTGS2/ATP2B4/AGT/BMP10/DPP4/FAP/NRP2/SP100/PPARG/WNT5A/FSTL1/SLIT2/KDR/ANXA3/EGF/VEGFC/SEMA5A/PLK2/SPARC/FGF18/ADTRP/EDN1/SASH1/BMPER/EPHB4/MET/PTN/LOXL2/STC1/ANGPT1/TEK/ANXA1/KLF4/NOTCH1/JCAD/NRP1/MMRN2/APOA1/PRKD1/BMP4/THBS1/CDH13/JUP/TGFB1/APOE/RRAS/RIN2/HMOX1/MYH9/CARD10/PDGFB/SRPX2 | 56 |
| CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | 38/1438 | 141/23056 | 0.2695035 | 4.321053 | 10.201867 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/S100A13/VAMP5/COL5A2/LAMB2/CCDC80/FSTL1/ITGB5/AMOTL2/PLAC8/DDR1/CCN2/CITED2/HOXA2/AQP1/SEMA3C/GAS1/GSN/COL5A1/NOTCH1/ANXA8L1/PAPSS2/ADM/PRSS23/SLC38A4/FOS/FBN1/SMAD6/MSLN/NUPR1/JUP/IFI35/COPZ2/COL1A1/LLGL2/SOCS3/KLF2/COL4A5 | 38 |
| CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | 42/1438 | 170/23056 | 0.2470588 | 3.961188 | 9.994469 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/TBX15/PRG4/EFEMP1/CAPG/COL3A1/SERPINE2/COL6A3/CCDC80/MUC13/MGLL/SEL1L3/IL7R/C9/RCAN2/MOXD1/VNN1/VNN2/THBS2/GPNMB/SERPINE1/SULF1/ERICH5/CTHRC1/GLIS3/COL5A1/FGFR2/YBX3/AMIGO2/LUM/TNFSF13B/MYO1E/LOXL1/COL1A1/SOCS3/MYOM1/GATA6/BMP2/MYL9/BACE2/MXRA5/BGN | 42 |
| REACTOME_SIGNALING_BY_INTERLEUKINS | REACTOME_SIGNALING_BY_INTERLEUKINS | REACTOME_SIGNALING_BY_INTERLEUKINS | 76/1438 | 463/23056 | 0.1641469 | 2.631829 | 9.148133 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/IL22RA1/VCAM1/S1PR1/CSF1/PTGS2/PTPN7/PTPN14/IL1R1/IL1A/IL1B/IL36G/FN1/IL17RC/IRAK2/BCL6/IL1RAP/TEC/CXCL8/CXCL1/CXCL2/IL15/IL7R/OSMR/IL31RA/TSLP/CSF2/H3C6/PSMB8/PSMB9/SOD2/IL6/CD36/PTPRZ1/CEBPD/CA1/GSDMD/ANXA1/IL15RA/MAP3K8/ALOX5/NFKB2/SAA1/MMP1/MMP3/CASP1/TNFRSF1A/STAT6/FOXO1/LCP1/NFKBIA/FOS/ANXA2/IL32/IL4R/IL21R/CTF1/MMP2/PSMB10/CCL5/CSF3/SOCS3/SERPINB2/CNN2/EBI3/ICAM1/IL27RA/IL12RB1/TGFB1/FPR1/IL11/LIF/HMOX1/IL2RB/MSN/IL13RA1 | 76 |
| GOBP_REGULATION_OF_CELL_SUBSTRATE_ADHESION | GOBP_REGULATION_OF_CELL_SUBSTRATE_ADHESION | GOBP_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 48/1438 | 217/23056 | 0.2211982 | 3.546554 | 9.720721 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/GBP1/CSF1/S100A10/NID1/VIT/FN1/EPHA3/COL8A1/PHLDB2/CCDC80/BCL6/KDR/NPNT/DAB2/EDIL3/RREB1/DDR1/UTRN/HOXA7/CD36/SERPINE1/COL26A1/PLEKHA2/HAS2/TEK/NOTCH1/NRP1/PLAU/VCL/PTPRJ/EFEMP2/FZD4/APOA1/ITGA5/MMP14/THBS1/CDH13/FOXF1/CCR7/JUP/ITGA3/COL1A1/RRAS/RIN2/SDC4/RAC2/PDGFB | 48 |
| AMIT_EGF_RESPONSE_480_HELA | AMIT_EGF_RESPONSE_480_HELA | AMIT_EGF_RESPONSE_480_HELA | 41/1438 | 164/23056 | 0.2500000 | 4.008345 | 9.971533 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/RHOC/SH2D2A/ITGA6/SERPINE2/TMEM158/ITGB5/TM4SF1/P3H2/OSMR/ITGA2/FST/FOXD1/HBEGF/ITPR3/TNFRSF21/TPBG/SERPINE1/ZYX/STC1/EXT1/B4GALT1/PTGS1/TOR4A/PLAU/NFKB2/PHLDA2/MICAL2/CD44/SERPINH1/GPRC5A/AMIGO2/ITGA5/ACTC1/TNFRSF12A/MT2A/MT1X/KRT17/MBP/IL11/TGM2 | 41 |
| BOQUEST_STEM_CELL_DN | BOQUEST_STEM_CELL_DN | BOQUEST_STEM_CELL_DN | 48/1438 | 218/23056 | 0.2201835 | 3.530285 | 9.681062 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/TIE1/IFI44L/S1PR1/NR5A2/RASGRP3/ITGA6/CAVIN2/TM4SF1/KDR/ANXA3/CFI/IL15/MYO10/HBEGF/ADRB2/ABLIM3/CLIC5/TPD52L1/STX11/AQP1/EPHB4/MET/TSPAN12/PODXL/STC1/TEK/JCAD/SRGN/MMRN2/HHEX/PTPRE/MMP1/MPZL2/VWF/RND1/FLT1/ALDH1A2/CSF3/MEOX1/HOXB7/PECAM1/DSG2/PLVAP/GMFG/THBD/TGM2/CARD10 | 48 |
| GOMF_COLLAGEN_BINDING | GOMF_COLLAGEN_BINDING | GOMF_COLLAGEN_BINDING | 26/1438 | 68/23056 | 0.3823529 | 6.130410 | 10.927232 | 0.0000000 | 0.0000000 | 0.0000000 | PODN/ITGA10/CTSS/NID1/FN1/LRRC15/ITGA2/TGFBI/SPARC/DDR1/ADGRG6/PDGFA/ADAM9/COL14A1/CD44/SERPINH1/VWF/LUM/NID2/THBS1/ITGA11/ITGA3/MRC2/C1QTNF1/COL6A2/PDGFB | 26 |
| SENESE_HDAC1_TARGETS_UP | SENESE_HDAC1_TARGETS_UP | SENESE_HDAC1_TARGETS_UP | 74/1438 | 451/23056 | 0.1640798 | 2.630754 | 9.020461 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/ZC3H12A/IFI16/LAMC2/LAMB3/NLRP3/NPAS2/IL1A/KYNU/ITGA6/TFPI/NABP1/MPP4/FN1/IRAK2/TGFBR2/TMEM158/TM4SF1/AADAC/ARL14/TMEM156/CXCL8/CXCL5/CXCL3/GPAT3/SLC7A11/VEGFC/TRIML2/IL7R/OSMR/ITGA2/ADAMTS6/FOXD1/CSF2/TRIM38/OGFRL1/TNFAIP3/SOD2/FAM126A/MET/ATP6V0A4/CEBPD/ASPH/TNFRSF11B/SRGN/PLAU/FAS/NFKB2/ITPRIP/NRIP3/SAA1/CD44/FOSL1/BIRC3/MMP1/MMP3/ROBO4/GLIPR1/NAV3/LCP1/NFKBIA/BCL2A1/TNFRSF12A/MLKL/DSG2/SERPINB2/SERPINB8/C3/PRNP/BMP2/TGM2/RAC2/SPANXB1/SPANXA1 | 74 |
| HALLMARK_COAGULATION | HALLMARK_COAGULATION | HALLMARK_COAGULATION | 37/1438 | 138/23056 | 0.2681159 | 4.298805 | 10.024484 | 0.0000000 | 0.0000000 | 0.0000000 | S100A13/CFH/DPP4/FN1/CFI/CTSO/C9/ITGA2/SPARC/SERPINE1/CLU/ADAM9/PLAT/ANXA1/GSN/MBL2/PLAU/HTRA1/PRSS23/MMP10/MMP1/MMP3/APOC3/APOA1/VWF/C1S/C1R/MMP14/SERPINA1/THBS1/FBN1/MMP2/PECAM1/SERPINB2/C3/THBD/PDGFB | 37 |
| KIM_WT1_TARGETS_12HR_UP | KIM_WT1_TARGETS_12HR_UP | KIM_WT1_TARGETS_12HR_UP | 41/1438 | 167/23056 | 0.2455090 | 3.936339 | 9.822120 | 0.0000000 | 0.0000000 | 0.0000000 | SYNC/CSF1/ATP2B4/LBH/MYLK/ITGB5/HEG1/TM4SF1/IL1RAP/FGFR3/C9/DAB2/HBEGF/ID4/DDR1/AQP1/TNS3/SERPINE1/PODXL/PLAT/MYBL1/TNFRSF11B/PLAU/ZCCHC24/MYOF/HTRA1/ADM/WT1/CREB3L1/SERPINH1/EPS8/BHLHE41/CA12/CSPG4/SOX9/GDF15/IL11/MYL9/GGT1/MN1/CSDC2 | 41 |
| GOBP_PEPTIDYL_TYROSINE_MODIFICATION | GOBP_PEPTIDYL_TYROSINE_MODIFICATION | GOBP_PEPTIDYL_TYROSINE_MODIFICATION | 66/1438 | 377/23056 | 0.1750663 | 2.806905 | 9.123221 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/ERRFI1/EPHA2/TIE1/TNFSF18/PTPRC/AGT/EFEMP1/TGFA/EPHA4/EPHA3/PARP14/HES1/FGFR3/ZFYVE28/DOK7/TXK/TEC/KDR/EPGN/EREG/BTC/EGF/IL15/PDGFC/IL31RA/TSLP/CSF2/HBEGF/BMP6/DDR1/ROS1/PDGFA/IL6/CD36/EPHB4/CAV1/MET/EPHB6/ANGPT1/TEK/NRP1/FGFR2/CD44/PTPRJ/TNFRSF1A/STYK1/GPRC5A/ITGA5/IGF1/FLT3/FLT1/LTK/EHD4/CSPG4/CTF1/CCL5/CSF3/PECAM1/SOCS3/AXL/TGFB1/IL11/PRNP/LIF/PDGFB | 66 |
| GOBP_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | 43/1438 | 183/23056 | 0.2349727 | 3.767406 | 9.693735 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/TIE1/ECM1/CD34/IL1A/IL1B/TGFBR2/CCR3/WNT5A/KDR/CXCL8/ANXA3/VEGFC/TLR3/SEMA5A/FGF18/SASH1/ITGB8/AQP1/BMPER/SERPINE1/TEK/KLF4/JCAD/NRP1/ADM/C3AR1/ITGA5/HMGA2/FLT1/PRKD1/THBS1/JUP/EMILIN2/GATA6/C3/HSPB6/C5AR1/RRAS/PTGIS/RUNX1/HMOX1/CYSLTR1 | 43 |
| HINATA_NFKB_TARGETS_FIBROBLAST_UP | HINATA_NFKB_TARGETS_FIBROBLAST_UP | HINATA_NFKB_TARGETS_FIBROBLAST_UP | 28/1438 | 81/23056 | 0.3456790 | 5.542403 | 10.562206 | 0.0000000 | 0.0000000 | 0.0000000 | NPAS2/IL1B/FN1/ADAMTS3/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/FGF5/EDN1/IER3/TNFAIP3/SOD2/IL6/SERPINE1/MYBL1/MSC/ANXA13/NFKB2/MMP1/KRT7/MMP14/NFKBIA/TNFAIP2/SERPINB2/ICAM1/RELB | 28 |
| MEISSNER_NPC_HCP_WITH_H3K4ME2 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | 78/1438 | 493/23056 | 0.1582150 | 2.536721 | 8.895583 | 0.0000000 | 0.0000000 | 0.0000000 | SYNC/NEXN/SYPL2/ADAMTSL4/S100A11/LGR6/NMI/TWIST2/HRH1/PRICKLE2/BMP3/NKD2/SLC12A7/ACOT12/ADRB2/ABLIM3/SOX30/FGF18/RNF144B/B3GALT4/ITPR3/RCAN2/COL12A1/PERP/FLNC/PARP12/LOXL2/EBF2/PLEKHA2/FZD6/NXNL2/AIFM2/SLC16A12/TLL2/PTPRE/TCERG1L/NRIP3/PRRG4/ALX4/CREB3L1/PCED1B/DNAJC15/CYP46A1/LTK/TNFAIP8L3/ANXA2/TPM1/ALDH1A3/IL4R/MT1X/RRAD/MLKL/ADAMTS18/PITPNM3/HS3ST3A1/ADAP2/FMNL1/COPZ2/DLX4/LLGL2/EMILIN2/MBP/GIPC3/WTIP/SCN1B/KCNK6/ADRA1D/KIAA1755/CEBPB/NFATC2/COL9A3/ADAMTS5/COL18A1/MN1/LIF/CARD10/IL13RA1/SLITRK4 | 78 |
| HUMMERICH_SKIN_CANCER_PROGRESSION_UP | HUMMERICH_SKIN_CANCER_PROGRESSION_UP | HUMMERICH_SKIN_CANCER_PROGRESSION_UP | 29/1438 | 87/23056 | 0.3333333 | 5.344460 | 10.470770 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/RHOC/CRABP2/COL5A2/CASP8/COL6A3/COL7A1/SERPINB1/PERP/SOD2/THBS2/SLC26A4/DOK2/IFITM3/CD44/CASP1/TNFRSF1A/ITGA5/MMP14/FOS/TNFRSF12A/IL4R/MT1X/KRT19/COL1A1/ITGB4/GADD45B/COL18A1/HMOX1 | 29 |
| ONDER_CDH1_TARGETS_3_DN | ONDER_CDH1_TARGETS_3_DN | ONDER_CDH1_TARGETS_3_DN | 24/1438 | 59/23056 | 0.4067797 | 6.522053 | 10.953306 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/TGFA/IL1B/IL36G/CXCL8/CXCL1/CXCL3/CXCL2/FST/CSF2/HBEGF/SERPINB1/EDN1/EHF/P2RY2/MMP10/GPRC5A/KRT8/NAV3/CSF3/KRT13/KRT15/SOX9/SERPINB2 | 24 |
| REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS | REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS | REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS | 24/1438 | 59/23056 | 0.4067797 | 6.522053 | 10.953306 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/LAMC2/LAMB3/ITGA6/COL3A1/COL5A2/FN1/LAMB2/ITGB5/ITGA2/DDR1/LAMA4/LAMA2/PDGFA/COL5A1/THBS1/COL1A1/ITGB4/TGFB1/SDC4/PDGFB/COL4A6/COL4A5 | 24 |
| TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | 68/1438 | 398/23056 | 0.1708543 | 2.739371 | 9.027704 | 0.0000000 | 0.0000000 | 0.0000000 | ARHGEF16/FUCA1/IFI44L/VCAM1/CSF1/CRABP2/IKBKE/CD34/ITPKB/HRH1/MITF/FSTL1/MME/HES1/CXCL8/IL7R/DAB2/GMPR/DDR1/GCM1/PTPRK/TNFAIP3/GPNMB/CLU/RBPMS/COL14A1/TRAF1/ITGA8/HHEX/NFKB2/IFITM3/HBD/ADM/BIRC3/CRYAB/APOC3/C1S/WNT10B/ALOX5AP/SLC10A2/NFKBIA/BMP4/LTBP2/FOS/SERPINA1/TNFAIP2/ACTC1/FBN1/TPM1/IL4R/CES1/CDH15/CCR7/JUP/HOXB2/HOXB13/ITGA3/COL1A1/SLC14A2/ELANE/MAG/CD22/APOE/RELB/SIRPA/RUNX1/MX2/MX1 | 68 |
| GOBP_MUSCLE_CELL_DIFFERENTIATION | GOBP_MUSCLE_CELL_DIFFERENTIATION | GOBP_MUSCLE_CELL_DIFFERENTIATION | 67/1438 | 389/23056 | 0.1722365 | 2.761533 | 9.036971 | 0.0000000 | 0.0000000 | 0.0000000 | SYPL2/CD53/CASQ1/LMOD1/AGT/BMP10/CYP26B1/DNER/RARB/HES1/EREG/NPNT/MYOZ2/PRDM6/EDN1/RBM24/TBX18/SOD2/CAV2/LMOD2/FLNC/SHH/NOTCH1/ITGA8/DKK1/MYPN/MYOZ1/SYNPO2L/ANKRD1/MYOF/FGFR2/ADM/WT1/EFEMP2/ADAMTS15/BHLHE41/WNT10B/IGF1/EDNRB/MMP14/NFATC4/BMP4/SIX1/SIX4/ACTC1/TPM1/RBPMS2/ALPK3/IL4R/MYLK3/FOXF1/PIEZO1/MYOCD/KRT19/SOX9/GATA6/ALPK2/TNFSF14/GDF15/TGFB1/EHD2/BMP2/MYL9/NFATC2/ADAMTS5/MYH9/PDGFB | 67 |
| AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP | 35/1438 | 126/23056 | 0.2777778 | 4.453717 | 10.025919 | 0.0000000 | 0.0000000 | 0.0000000 | SH2D2A/IFI16/PTGS2/CFH/LTBP1/TGFA/ITGB6/COL5A2/AOX1/CPS1/FN1/SERPINE2/HRH1/TGFBR2/CLDN1/FST/PLK2/PTPRK/VNN1/DDX58/B4GALT1/COL5A1/SRGN/MMP3/NNMT/ARHGDIB/THBS1/CA12/NUPR1/CSF3/EMP3/PRNP/MX1/APOBEC3G/IL13RA1 | 35 |
| GOBP_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | GOBP_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | GOBP_RESPONSE_TO_TUMOR_NECROSIS_FACTOR | 51/1438 | 248/23056 | 0.2056452 | 3.297187 | 9.380648 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/TNFRSF4/TNFRSF1B/ZC3H12A/GBP3/GBP1/GBP2/VCAM1/TNFSF18/PTGS2/CASP8/CLDN1/HES1/CXCL8/NPNT/ADAMTS12/F2RL1/CRHBP/EDN1/TNFRSF21/TNFAIP3/CCL26/ADAM9/FABP4/EXT1/HAS2/TRAF1/FAS/ANKRD1/BIRC3/CASP4/CASP1/CARD16/APOA1/TNFRSF1A/YBX3/KRT18/TNFRSF19/TNFSF13B/NFKBIA/ZFP36L1/THBS1/CCL5/COL1A1/TNFRSF11A/MBP/CD70/KLF2/PLVAP/ZFP36/BIRC7 | 51 |
| GOBP_POSITIVE_REGULATION_OF_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_CHEMOTAXIS | 37/1438 | 140/23056 | 0.2642857 | 4.237393 | 9.909330 | 0.0000000 | 0.0000000 | 0.0000000 | EDN2/S1PR1/CSF1/WNT5A/SUCNR1/SLIT2/KDR/CXCL8/VEGFC/SEMA5A/ITGA2/F2RL1/FGF18/EDN1/GPSM3/PLA2G7/TPBG/IL6/CCL26/SERPINE1/MET/PTN/RARRES2/NRP1/C3AR1/NCKAP1L/PRKD1/THBS1/CDH13/CCL5/CCR7/TNFSF14/TGFB1/C5AR1/DEFB124/RAC2/PDGFB | 37 |
| GOBP_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | GOBP_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | GOBP_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 56/1438 | 291/23056 | 0.1924399 | 3.085461 | 9.233558 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ZC3H12A/PTGS2/ATP2B4/TGFB2/AGT/BMP10/NRP2/SP100/PPARG/TGFBR2/WNT5A/SLIT2/KDR/ANXA3/EGF/VEGFC/SEMA5A/ITGA2/PLK2/HBEGF/SPARC/FGF18/RREB1/EDN1/SASH1/BMPER/SEMA3A/MET/PTN/STC1/ADAM9/ANGPT1/HAS2/EPPK1/TEK/ANXA1/KLF4/NOTCH1/JCAD/NRP1/MMRN2/PRKD1/BMP4/THBS1/JUP/ITGA3/SOX9/TGFB1/APOE/RRAS/RIN2/HMOX1/CARD10/PDGFB/SRPX2 | 56 |
| RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 17/1438 | 28/23056 | 0.6071429 | 9.734552 | 11.927400 | 0.0000000 | 0.0000000 | 0.0000000 | NID1/DLX2/DAB2/CCNO/TFAP2A/HLA-E/HLA-C/MICB/CCN2/MDFIC/ANXA1/HTRA1/PHLDA2/GADD45B/EMP3/MN1/GPC4 | 17 |
| GOMF_GROWTH_FACTOR_ACTIVITY | GOMF_GROWTH_FACTOR_ACTIVITY | GOMF_GROWTH_FACTOR_ACTIVITY | 40/1438 | 162/23056 | 0.2469136 | 3.958859 | 9.747095 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/TGFB2/AGT/EFEMP1/BMP10/TGFA/CXCL1/EPGN/EREG/BTC/FGF5/BMP3/EGF/PDGFC/VEGFC/GDNF/CSF2/HBEGF/FGF18/BMP6/CCN2/PDGFA/MACC1/IL6/INHBA/PTN/FGF20/GDF6/DKK1/IGF1/BMP4/OSGIN1/CSF3/GDF15/GMFG/TGFB1/IL11/BMP2/LIF/PDGFB | 40 |
| REACTOME_ECM_PROTEOGLYCANS | REACTOME_ECM_PROTEOGLYCANS | REACTOME_ECM_PROTEOGLYCANS | 27/1438 | 76/23056 | 0.3552632 | 5.696069 | 10.575977 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/TGFB2/ITGB6/COL3A1/COL5A2/FN1/COL6A3/LAMB2/ITGB5/ITGA2/HAPLN1/SPARC/LAMA4/LAMA2/SERPINE1/COL5A1/ITGA8/ITGA7/LUM/COL1A1/TGFB1/COL9A3/COL6A2/COL4A6/COL4A5/BGN | 27 |
| REACTOME_ELASTIC_FIBRE_FORMATION | REACTOME_ELASTIC_FIBRE_FORMATION | REACTOME_ELASTIC_FIBRE_FORMATION | 21/1438 | 45/23056 | 0.4666667 | 7.482244 | 11.225821 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/LTBP1/EFEMP1/BMP10/ITGB6/FN1/ITGB5/ITGB8/LOXL2/ITGA8/LOXL4/EFEMP2/ITGA5/BMP4/LTBP2/FBLN5/FBN1/LOXL1/EMILIN2/TGFB1/BMP2 | 21 |
| GOCC_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE | GOCC_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE | GOCC_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE | 73/1438 | 448/23056 | 0.1629464 | 2.612582 | 8.889636 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/TNFRSF4/TNFRSF9/ECE1/VCAM1/S1PR1/ITGA10/MR1/PTPRC/CD34/IL1R1/ITGB6/ITGA6/ITGA4/SERPINE2/TRPM8/ACKR3/TGFBR2/ACKR2/CCR3/HEG1/KDR/ABCG2/IL7R/OSMR/ITGA2/IL31RA/HFE/MOG/HLA-E/MICA/MICB/NT5E/RAET1E/CD36/MSR1/ADAM9/CD274/PDCD1LG2/B4GALT1/TMC1/ANXA1/ITGA8/FAS/KLRD1/KLRC4-KLRK1/ITGA5/ITGA7/THBS1/ITGA11/MFGE8/ANPEP/IL4R/IL21R/CDH13/CCR7/ITGA3/TNFRSF11A/EBI3/ADGRE1/CLEC4M/ICAM1/IL27RA/IL12RB1/CD22/BCAM/PRNP/PRND/THBD/ICOSLG/IL2RB/IL13RA1/GPC4 | 73 |
| WESTON_VEGFA_TARGETS | WESTON_VEGFA_TARGETS | WESTON_VEGFA_TARGETS | 30/1438 | 95/23056 | 0.3157895 | 5.063173 | 10.234955 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/CD34/EFEMP1/FAP/COL6A3/KDR/SULT1E1/CXCL1/SEMA5A/BMP6/MEST/AQP7/ANKRD1/MMP10/MMP1/NNMT/VWF/C1S/KRT7/KRT18/POSTN/FOXO1/NID2/BMP4/IL32/MMP2/ADGRE1/SDC4/SAT1/BGN | 30 |
| MAHAJAN_RESPONSE_TO_IL1A_UP | MAHAJAN_RESPONSE_TO_IL1A_UP | MAHAJAN_RESPONSE_TO_IL1A_UP | 27/1438 | 77/23056 | 0.3506494 | 5.622094 | 10.477866 | 0.0000000 | 0.0000000 | 0.0000000 | LMOD1/IL1B/ACKR3/COL7A1/KDR/CXCL5/CXCL3/CXCL2/IL7R/CSF2/HBEGF/EDN1/SOD2/MAFK/IL6/PTPRZ1/B4GALT1/IL15RA/OASL/FLT1/TNFAIP2/THBS1/CCL5/SERPINB2/FSTL3/IL2RB/CHST7 | 27 |
| GOCC_MEMBRANE_MICRODOMAIN | GOCC_MEMBRANE_MICRODOMAIN | GOCC_MEMBRANE_MICRODOMAIN | 60/1438 | 329/23056 | 0.1823708 | 2.924021 | 9.065481 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/S1PR1/S100A10/PTGS2/PTPRC/ATP2B4/LAX1/DPP4/TFPI/CAVIN2/CASP8/TRPM8/TGFBR2/GASK1A/MME/KDR/ABCG2/ADTRP/GJA1/SYNJ2/CD36/CAV2/CAV1/PODXL/SHH/TNFRSF10A/SULF1/ANGPT1/HAS2/ADCY8/LY6K/TEK/FAS/MYOF/MS4A4A/AHNAK/SERPINH1/BIRC3/KCNA5/TNFRSF1A/STAT6/SELPLG/TRPC4/EDNRB/ANXA2/LAT/CDH13/CDH15/CAVIN1/SGCA/PECAM1/ICAM1/PLVAP/MAG/EHD2/PRNP/SDC4/PTGIS/HMOX1/MLC1 | 60 |
| SWEET_KRAS_TARGETS_UP | SWEET_KRAS_TARGETS_UP | SWEET_KRAS_TARGETS_UP | 28/1438 | 83/23056 | 0.3373494 | 5.408851 | 10.377909 | 0.0000000 | 0.0000000 | 0.0000000 | ECE1/HSPG2/ATP2B4/TGFB2/LBH/SERPINE2/ACKR3/BHLHE40/COL7A1/INPP4B/TGFBI/SPARC/ADAM19/SERPINE1/TCIM/MSC/MATN2/COL5A1/MAP3K8/TAGLN/C1S/GLIPR1/NUAK1/GOLGA8F/TPM1/COL1A1/GADD45B/MYL9 | 28 |
| JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | JAATINEN_HEMATOPOIETIC_STEM_CELL_DN | 49/1438 | 235/23056 | 0.2085106 | 3.343130 | 9.311449 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/NEXN/FCGR2A/NID1/LBH/TRABD2A/EPHA4/SPON2/LEF1/GYPA/IL7R/TGFBI/ADTRP/RHAG/SAMD3/TNFAIP3/CITED2/STX11/CD36/DOK2/CEBPD/MYBL1/CA1/AQP3/PCSK5/KLF4/HBD/ZFP36L1/SERPINA1/THBS1/IL21R/LAT/COTL1/CRISPLD2/SLFN5/CCL5/CCR7/MYL4/SLC14A1/SERPINB2/S1PR5/KLF2/BLVRB/C5AR1/FPR1/IL2RB/LGALS2/IL13RA1/TENM1 | 49 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_CELL_ADHESION | 57/1438 | 305/23056 | 0.1868852 | 2.996402 | 9.052154 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ZC3H12A/GBP1/PTPN22/ILDR2/PTPRC/LAX1/EPHA4/SERPINE2/PHLDB2/BCL6/SEMA5A/TGFBI/BMP6/ADTRP/HFE/TNFRSF21/GPNMB/HOXA7/GLI3/SERPINE1/PODXL/SHH/ZNF703/IDO1/ANGPT1/CD274/PDCD1LG2/ANXA1/KLF4/NOTCH1/SFTPD/LRRC32/FZD4/APOA1/UBASH3B/ARHGDIB/RND1/NCKAP1L/MMP14/BMP4/THBS1/IL4R/MMP2/ADAMTS18/CDH13/COL1A1/C1QTNF1/MBP/FXYD5/TGFB1/IL4I1/PRNP/BMP2/SDC4/CEBPB/RUNX1 | 57 |
| GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | 50/1438 | 245/23056 | 0.2040816 | 3.272118 | 9.221383 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/VCAM1/PTPN22/PTPRC/ITPKB/NLRP3/IL1A/IL1B/DPP4/ITGA4/TGFBR2/BCL6/HES1/LEF1/IL15/IL7R/HLA-E/VNN1/IL6/GLI3/CAV1/SHH/HAS2/CD274/PDCD1LG2/ANXA1/MAP3K8/ALOX5/CD44/KLRC4-KLRK1/NCKAP1L/TESPA1/IGF1/TNFSF13B/IL4R/CCL5/CCR7/ELANE/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/IL4I1/SIRPG/SIRPA/RUNX1/ICOSLG/LGALS1 | 50 |
| REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES | REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES | REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES | 25/1438 | 67/23056 | 0.3731343 | 5.982604 | 10.533872 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/P3H2/ADAMTS3/ADAMTS2/COL21A1/COL19A1/COL12A1/COL26A1/COL14A1/COL27A1/COL5A1/COL13A1/TLL2/P4HA3/SERPINH1/COL1A1/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 25 |
| PLASARI_TGFB1_TARGETS_10HR_DN | PLASARI_TGFB1_TARGETS_10HR_DN | PLASARI_TGFB1_TARGETS_10HR_DN | 51/1438 | 254/23056 | 0.2007874 | 3.219301 | 9.172776 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/GBP2/VCAM1/PRRX1/RNASEL/OSR1/RASGRP3/NMI/CAVIN2/RARB/PRICKLE2/PLSCR2/RTP4/FAT4/NPR3/DAB2/FOXC1/SERPINB1/LAMA4/RSPO3/ARHGAP18/ADGRG6/AQP1/CD36/SEMA3A/PDK4/FOXP2/MEST/ZNF467/PDLIM2/RSPO2/TRPS1/GAS1/S1PR3/PPP1R3C/TCF7L2/FGFR2/ADM/VWA5A/C3AR1/LUM/IGF1/EDNRB/SIX1/NQO1/SLC14A1/THBD/ADAMTS5/SIM2/USP18/LPAR4 | 51 |
| GOBP_ODONTOGENESIS | GOBP_ODONTOGENESIS | GOBP_ODONTOGENESIS | 35/1438 | 130/23056 | 0.2692308 | 4.316679 | 9.780594 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/CD34/TGFB2/OSR1/ITGB6/DLX1/DLX2/AMTN/ENAM/LEF1/FST/FOXC1/TFAP2A/EDN1/RUNX2/PERP/FAM20C/AQP1/INHBA/GLI3/SERPINE1/SHH/RSPO2/TNFRSF11B/AQP3/FGFR2/HTRA1/ADM/BMP4/SLC24A4/DLX3/COL1A1/GATA6/BMP2/ADAMTS5 | 35 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | 39/1438 | 159/23056 | 0.2452830 | 3.932716 | 9.570475 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/ECM1/ADAMTSL4/IFI16/TM4SF1/FNDC3B/IL1RAP/CXCL5/SLC7A11/PLK2/CRHBP/DDR1/TNFRSF21/PDGFA/GPNMB/TPK1/RBPMS/PLAT/EXT1/GPR20/PAPSS2/MYOF/TCF7L2/SLC15A3/C3AR1/EMP1/AMIGO2/CPM/SERPINA1/ALDH1A2/ANXA2/BCL2A1/NUPR1/NQO1/MAF/SOCS3/ELANE/KLF2/GDF15 | 39 |
| GOBP_HEART_MORPHOGENESIS | GOBP_HEART_MORPHOGENESIS | GOBP_HEART_MORPHOGENESIS | 51/1438 | 255/23056 | 0.2000000 | 3.206676 | 9.138732 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/CCN1/S1PR1/TGFB2/BMP10/XIRP2/NRP2/TGFBR2/TNNC1/WNT5A/HEG1/HES1/FGFRL1/SLIT2/FOXC1/DSP/EDN1/GJA1/CITED2/ADGRG6/SEMA3C/FZD1/EPHB4/SHH/ZFPM2/EXT1/HAS2/TEK/COL5A1/NOTCH1/NRP1/DKK1/SYNPO2L/ANKRD1/FGFR2/MICAL2/YAP1/BMP4/SIX1/ACTC1/ALDH1A2/TPM1/SMAD6/FOXF1/NOG/SOX9/GATA6/ALPK2/TGFB1/BMP2/GATA5 | 51 |
| PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 67/1438 | 399/23056 | 0.1679198 | 2.692322 | 8.794729 | 0.0000000 | 0.0000000 | 0.0000000 | SPOCD1/S100A2/S100A16/NR5A2/TGFA/LONRF2/RPRM/ITGB6/TFPI/SP100/PHLDB2/ITGB5/MGLL/WWTR1/FNDC3B/CLDN1/TMEM156/ABCG2/NPNT/VEGFC/MYO10/GALNT10/MICA/MICB/NT5E/TPD52L1/MAFK/PRR15/CAV2/MET/TNFRSF10A/LOXL2/STC1/ADAM9/GLIS3/AIF1L/CLIC3/IL15RA/COL13A1/ANKRD22/PPP1R3C/MYOF/CD44/MMP1/DNAJC22/ITGA5/ACSS3/DRAM1/LATS2/LRP10/SIX1/MYO1E/ANXA2/CA12/BCL2A1/ALDH1A3/CAVIN1/ITGA3/DSG2/FSTL3/FXYD5/PLA2G4C/IL11/SDCBP2/PROCR/IL13RA1/ZNF185 | 67 |
| AMIT_SERUM_RESPONSE_240_MCF10A | AMIT_SERUM_RESPONSE_240_MCF10A | AMIT_SERUM_RESPONSE_240_MCF10A | 23/1438 | 57/23056 | 0.4035088 | 6.469609 | 10.663346 | 0.0000000 | 0.0000000 | 0.0000000 | GBP1/TGFA/ITGB6/TM4SF1/CLDN1/ITGA2/FST/GRAMD2B/ADRB2/ABLIM3/TNFRSF21/SERPINE1/DKK1/PHLDA2/EMP1/ITGA5/GLIPR1/THBS1/EHD4/ALDH1A3/SERPINB2/NECTIN2/CDC42EP1 | 23 |
| GOBP_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 75/1438 | 477/23056 | 0.1572327 | 2.520972 | 8.657295 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/CCN1/CSF1/PIFO/PTPRC/ATP2B4/TGFB2/AGT/TGFA/IL1B/EPHA4/TGFBR2/WNT5A/EPHA3/FGFR3/DOK7/KDR/EPGN/EREG/BTC/EGF/PDGFC/VEGFC/TLR3/HBEGF/ADRB2/FGF18/EDN1/DDR1/ROS1/TPD52L1/SASH1/PDGFA/EPHB4/MET/EPHB6/ARHGEF5/TNFRSF10A/CLU/ADAM9/TCIM/ANGPT1/ADCY8/TEK/TNFSF15/FZD8/DKK1/FGFR2/FZD4/GPRC5A/NCKAP1L/HMGA2/IGF1/FLT3/FLT1/AJUBA/PRKD1/THBS1/LTK/TNFAIP8L3/LAT/CCL5/CCR7/GPRC5C/TNFRSF11A/ELANE/AXL/TGFB1/PRNP/BMP2/SDC4/CARD10/PDGFB/TENM1 | 75 |
| MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | 52/1438 | 265/23056 | 0.1962264 | 3.146173 | 9.062753 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/FUCA1/PTPN22/HMCN1/NID1/LBH/NMI/DPP4/GALNT3/KCNE4/FOXL2/TM4SF1/CLDN1/IL1RAP/SLC7A11/NPR3/HAPLN1/FGF18/HLA-E/MDFI/COL21A1/PODXL/AKR1B10/RARRES2/ZNF703/JCAD/FZD8/FAS/FZD4/MMP3/CRYAB/ARHGDIB/BHLHE41/KRT18/NFATC4/SIX1/FBLN5/PAQR5/CES1/KRT19/SIGLEC15/ICAM1/KLF2/CDC42EP5/SDCBP2/SIRPA/ADRA1D/PRND/TGM2/APOL6/XG/ARHGEF6 | 52 |
| GOBP_MUSCLE_SYSTEM_PROCESS | GOBP_MUSCLE_SYSTEM_PROCESS | GOBP_MUSCLE_SYSTEM_PROCESS | 72/1438 | 449/23056 | 0.1603563 | 2.571054 | 8.670559 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/TNFRSF1B/HTR1D/TRIM63/ZC3H12A/EDN2/CASQ1/PTGS2/LMOD1/ATP2B4/AGT/BMP10/IL1B/DES/KCNE4/PPARG/TNNC1/MYLK/NPNT/MYOZ2/TRPC3/IL15/GDNF/ITGA2/ADRB2/DSP/EDN1/GJA1/TRDN/CCN2/UTRN/CAV1/LMOD2/STC1/ASPH/SULF1/FBXO32/TPM2/GSN/NOTCH1/MYOZ1/HTR7/MYOF/ARHGAP42/CRYAB/KCNA5/TNFRSF1A/SPX/IGF1/FOXO1/EDNRB/TPM1/HCN4/MYH13/MYH8/MYH4/MYH1/MYH2/MYOCD/JUP/MYL4/SGCA/KCNJ2/MYOM1/GATA6/DSG2/CNN1/SCN1B/MYL9/GATA5/HMOX1/SMPX | 72 |
| JINESH_BLEBBISHIELD_TRANSFORMED_STEM_CELL_SPHERES_UP | JINESH_BLEBBISHIELD_TRANSFORMED_STEM_CELL_SPHERES_UP | JINESH_BLEBBISHIELD_TRANSFORMED_STEM_CELL_SPHERES_UP | 41/1438 | 176/23056 | 0.2329545 | 3.735049 | 9.393937 | 0.0000000 | 0.0000000 | 0.0000000 | SPOCD1/LAMC2/NIBAN1/LAMB3/KYNU/MLPH/WNT5A/AADAC/ARL14/GPAT3/SPP1/SLC7A11/IL7R/F2RL1/TNFRSF21/SOD2/SAMD9/SERPINE1/AKR1B10/AKR1B15/FBXO32/ST3GAL1/ANXA1/PTGR1/ANXA8/CD44/AHNAK/EMP1/THBS1/ANXA2/ALDH1A3/MT1X/NQO1/SLC16A5/SLC14A1/SERPINB8/CYP4F11/LYPD3/SDCBP2/MX1/HMOX1 | 41 |
| GOBP_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_CELL_ADHESION_MEDIATED_BY_INTEGRIN | 28/1438 | 86/23056 | 0.3255814 | 5.220170 | 10.112370 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ITGA10/TGFB2/ITGB6/DPP4/ITGA6/ITGA4/ITGB5/NPNT/ITGA2/ITGB8/SERPINE1/PODXL/ADAM9/EXT1/ITGA8/PLAU/ITGA5/NCKAP1L/ITGA7/FBN1/ITGA11/PIEZO1/CCL5/ITGA3/ITGB4/ICAM1/LIF | 28 |
| SENESE_HDAC1_TARGETS_DN | SENESE_HDAC1_TARGETS_DN | SENESE_HDAC1_TARGETS_DN | 52/1438 | 266/23056 | 0.1954887 | 3.134345 | 9.029995 | 0.0000000 | 0.0000000 | 0.0000000 | C1QTNF12/SYNC/S100A10/TGFB2/LYPD1/COL3A1/IQCA1/THRB/LAMB2/GXYLT2/PHLDB2/FSTL1/MYLK/P3H2/FAM114A1/C9/HAPLN1/EDIL3/TGFBI/ID4/RUNX2/COL12A1/UTRN/PDE1C/RBPMS/MYBL1/GSN/COL5A1/ALOX5/LOXL4/EPS8L2/MYRF/AHNAK/EFEMP2/KRT7/ITGA7/PYGL/BMP4/FOS/LACTB/MAF/CAVIN1/COL1A1/ABCC3/MRC2/CNN1/BCAM/FOXS1/MYL9/ELFN2/CSDC2/GPC4 | 52 |
| WP_LUNG_FIBROSIS | WP_LUNG_FIBROSIS | WP_LUNG_FIBROSIS | 24/1438 | 63/23056 | 0.3809524 | 6.107954 | 10.470651 | 0.0000000 | 0.0000000 | 0.0000000 | TGFA/IL1B/CCR3/CXCL8/CXCL2/SPP1/EGF/CSF2/DSP/EDN1/CCN2/PDGFA/IL6/PLAU/IGF1/SERPINA1/MMP2/MT2A/CCL5/CSF3/TGFB1/CEBPB/HMOX1/PDGFB | 24 |
| REACTOME_LAMININ_INTERACTIONS | REACTOME_LAMININ_INTERACTIONS | REACTOME_LAMININ_INTERACTIONS | 17/1438 | 30/23056 | 0.5666667 | 9.085582 | 11.429228 | 0.0000000 | 0.0000000 | 0.0000000 | HSPG2/LAMC2/LAMB3/NID1/ITGA6/COL7A1/LAMB2/ITGA2/LAMA4/LAMA2/ITGA7/NID2/ITGA3/ITGB4/COL18A1/COL4A6/COL4A5 | 17 |
| GOBP_REGULATION_OF_CHEMOTAXIS | GOBP_REGULATION_OF_CHEMOTAXIS | GOBP_REGULATION_OF_CHEMOTAXIS | 47/1438 | 225/23056 | 0.2088889 | 3.349195 | 9.132761 | 0.0000000 | 0.0000000 | 0.0000000 | EDN2/S1PR1/CSF1/DPP4/SEMA3B/WNT5A/SUCNR1/SLIT2/KDR/CXCL8/VEGFC/SEMA5A/ITGA2/F2RL1/FGF18/EDN1/GPSM3/PLA2G7/TPBG/IL6/CCL26/SEMA3C/SEMA3A/SEMA3D/SERPINE1/MET/PTN/RARRES2/NOTCH1/NRP1/C3AR1/KLRC4-KLRK1/NCKAP1L/PRKD1/THBS1/CYP19A1/CDH13/CCL5/CCR7/ELANE/SEMA6B/TNFSF14/TGFB1/C5AR1/DEFB124/RAC2/PDGFB | 47 |
| CROMER_TUMORIGENESIS_UP | CROMER_TUMORIGENESIS_UP | CROMER_TUMORIGENESIS_UP | 23/1438 | 58/23056 | 0.3965517 | 6.358064 | 10.537344 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/IL1B/FAP/COL3A1/COL5A2/FN1/LRRC15/CXCL8/CXCL1/SPP1/SPARC/TNFAIP3/IL6/SERPINE1/PLAU/MMP10/MMP1/MMP3/LUM/OASL/POSTN/KRT17/MAGEA1 | 23 |
| HUPER_BREAST_BASAL_VS_LUMINAL_DN | HUPER_BREAST_BASAL_VS_LUMINAL_DN | HUPER_BREAST_BASAL_VS_LUMINAL_DN | 23/1438 | 58/23056 | 0.3965517 | 6.358064 | 10.537344 | 0.0000000 | 0.0000000 | 0.0000000 | FUCA1/CCN1/EFEMP1/MLPH/SEMA3B/TM4SF1/PSMB8/PSMB9/DKK1/PLAAT3/GPRC5A/KRT8/KRT18/TNFAIP2/LOXL1/ANPEP/IL32/CLDN7/KRT15/KRT19/KLK6/ADAMTS5/BACE2 | 23 |
| JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 25/1438 | 69/23056 | 0.3623188 | 5.809196 | 10.318346 | 0.0000000 | 0.0000000 | 0.0000000 | GBP4/PTPN22/CFH/COL3A1/ACKR3/CXCL6/CXCL2/DAB2/PPIC/SPARC/PLA2G7/INHBA/GAS1/PTGS1/HTRA1/IFITM3/SERPINH1/MMP2/CDH15/CD68/BCL3/RRAS/IL11/PROCR/COL6A2 | 25 |
| GOBP_REGULATION_OF_BODY_FLUID_LEVELS | GOBP_REGULATION_OF_BODY_FLUID_LEVELS | GOBP_REGULATION_OF_BODY_FLUID_LEVELS | 65/1438 | 385/23056 | 0.1688312 | 2.706934 | 8.710961 | 0.0000000 | 0.0000000 | 0.0000000 | PLA2G4A/CD34/CYP26B1/FAP/TFPI/COL3A1/FN1/SERPINE2/HEG1/CLDN1/TXK/TEC/SLC7A11/NPR3/ITGA2/F2RL1/ADTRP/EDN1/DDR1/TREML1/GJA1/PDGFA/IL6/AQP1/CD36/SERPINE1/CAV1/MET/SHH/PLAT/FZD6/EXT1/HAS2/AQP3/ANXA8/PLAU/VCL/PAPSS2/NLRP6/TSPAN32/ADM/SAA1/P2RY2/UBASH3B/VWF/SCNN1A/NFE2/EDNRB/SERPINA10/SERPINA1/THBS1/FOXB1/ADAMTS18/C1QTNF1/EMILIN2/SERPINB2/CYP4F11/AXL/KCNN4/APOE/THBD/PROCR/MYL9/MYH9/PDGFB | 65 |
| KRIEG_HYPOXIA_VIA_KDM3A | KRIEG_HYPOXIA_VIA_KDM3A | KRIEG_HYPOXIA_VIA_KDM3A | 22/1438 | 53/23056 | 0.4150943 | 6.655365 | 10.630669 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/EDN2/LAMC2/LAMB3/NRP2/COL7A1/TM4SF1/IL1RAP/CXCL1/CXCL5/EDN1/SERPINE1/ASPH/FBXO32/PHLDA2/ADM/BIRC3/HMGA2/SERPINB8/GDF15/TGM2/HMOX1 | 22 |
| GOMF_CYTOKINE_ACTIVITY | GOMF_CYTOKINE_ACTIVITY | GOMF_CYTOKINE_ACTIVITY | 48/1438 | 234/23056 | 0.2051282 | 3.288898 | 9.076363 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/TNFSF18/TGFB2/WNT9A/BMP10/IL1A/IL1B/IL36G/CMTM8/WNT5A/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/BMP3/SPP1/IL15/TSLP/CSF2/BMP6/EDN1/IL6/INHBA/CCL26/GDF6/TNFRSF11B/IFNE/TNFSF15/WNT10B/TNFSF13B/BMP4/IL32/CTF1/CCL5/CSF3/EBI3/TNFSF9/CD70/TNFSF14/GDF15/TGFB1/IL11/BMP2/LIF/WNT7B/NDP | 48 |
| SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | 26/1438 | 75/23056 | 0.3466667 | 5.558238 | 10.197588 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP1/SLIT2/ABCG2/DDX60/TENT5A/SEMA3A/SAMD9/PTN/ADAM28/CLU/IDO1/DDX58/KLF4/PLAAT4/GPRC5A/IGFBP6/OASL/BMP4/ALDH1A3/CRISPLD2/CCL5/LIPG/MX2/MX1/NDP | 26 |
| GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_UP | 24/1438 | 64/23056 | 0.3750000 | 6.012517 | 10.356470 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/NIBAN1/PTGS2/PTPRC/IL1B/KYNU/TFPI/TM4SF1/CXCL6/CXCL1/CXCL3/CXCL2/CRHBP/TPBG/VNN1/SOD2/INHBA/RBPMS/ALOX5/TCF7L2/MPZL2/EMP1/GLIPR1/EBI3 | 24 |
| REACTOME_COLLAGEN_DEGRADATION | REACTOME_COLLAGEN_DEGRADATION | REACTOME_COLLAGEN_DEGRADATION | 24/1438 | 64/23056 | 0.3750000 | 6.012517 | 10.356470 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/COL19A1/COL12A1/COL26A1/ADAM9/COL14A1/COL5A1/COL13A1/MMP10/MMP1/MMP3/MMP14/MMP2/COL1A1/ELANE/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 24 |
| GOBP_LEUKOCYTE_PROLIFERATION | GOBP_LEUKOCYTE_PROLIFERATION | GOBP_LEUKOCYTE_PROLIFERATION | 59/1438 | 331/23056 | 0.1782477 | 2.857914 | 8.780956 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF4/TNFRSF1B/VCAM1/CSF1/PTPN22/TNFSF18/PTPRC/IL1A/IL1B/TGFBR2/BCL6/HES1/LEF1/IL15/NPR3/IL7R/F2RL1/CSF2/MZB1/DOCK2/HLA-E/TNFRSF21/GJA1/TNFAIP3/AHR/IL6/GPNMB/SHH/CLU/IDO1/CD274/PDCD1LG2/IFNE/ANXA1/SFTPD/HHEX/LRRC32/NCKAP1L/IGF1/FLT3/TNFSF13B/BMP4/PSMB10/CCL5/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/CD22/IL4I1/PRNP/SDC4/CEBPB/NFATC2/ICOSLG/RAC2/MSN | 59 |
| GOBP_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT | GOBP_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT | GOBP_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT | 34/1438 | 127/23056 | 0.2677165 | 4.292401 | 9.595691 | 0.0000000 | 0.0000000 | 0.0000000 | TBX15/PRRX1/WNT9A/OSR1/DLX1/DLX2/TGFBR2/WNT5A/NKX3-2/TFAP2A/MDFI/RUNX2/HOXA1/HOXA2/HOXA3/HOXA7/GLI3/SHH/SULF1/EXT1/DMRT2/PCSK5/FGFR2/ALX4/MMP14/BMP4/SIX1/SIX4/LHX1/HOXB2/HOXB3/HOXB7/COL1A1/NOG | 34 |
| ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | 72/1438 | 454/23056 | 0.1585903 | 2.542739 | 8.562510 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/SPSB1/HSPB7/ZC3H12A/BTBD19/PTGS2/IL1R1/IL1A/IL1B/KCNE4/IRAK2/XIRP1/WNT5A/FNDC3B/SOD3/CXCL1/CXCL3/CXCL2/EREG/SGMS2/HAPLN1/TSLP/SLC22A23/PXDC1/EDN1/RNF144B/ID4/IER3/TNFAIP3/SOD2/ITGB8/IL6/SERPINE1/COL26A1/FOXP2/MSC/CA13/ST3GAL1/DMRTA1/B4GALT1/S1PR3/TNFSF15/TRAF1/NFKB2/ITPRIP/TCF7L2/ADM/CD44/FOSL1/DRAM1/NFKBIA/TNFAIP2/SLC28A1/CTF1/CDH15/CSF3/KRT19/SERPINB2/SERPINB8/TNFSF9/ICAM1/RELB/BFSP1/SDC4/ICOSLG/MN1/LIF/PDGFB/NDP/STARD8/KLHL4/MAGEA10 | 72 |
| GOBP_HEMOSTASIS | GOBP_HEMOSTASIS | GOBP_HEMOSTASIS | 47/1438 | 228/23056 | 0.2061404 | 3.305127 | 9.021578 | 0.0000000 | 0.0000000 | 0.0000000 | PLA2G4A/CD34/FAP/TFPI/COL3A1/FN1/SERPINE2/TXK/TEC/SLC7A11/ITGA2/F2RL1/ADTRP/EDN1/TREML1/PDGFA/IL6/CD36/SERPINE1/CAV1/SHH/PLAT/FZD6/ANXA8/PLAU/VCL/PAPSS2/TSPAN32/SAA1/UBASH3B/VWF/NFE2/SERPINA10/SERPINA1/THBS1/ADAMTS18/C1QTNF1/EMILIN2/SERPINB2/CYP4F11/AXL/APOE/THBD/PROCR/MYL9/MYH9/PDGFB | 47 |
| GROSS_HYPOXIA_VIA_ELK3_DN | GROSS_HYPOXIA_VIA_ELK3_DN | GROSS_HYPOXIA_VIA_ELK3_DN | 38/1438 | 157/23056 | 0.2420382 | 3.880691 | 9.340980 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/CCN1/IFI16/PTGS2/ITGA6/BHLHE40/TM4SF1/CXCL6/CXCL3/CXCL2/SLC7A11/FST/PLK2/HBEGF/EDN1/GJA1/CCN2/IL6/TCIM/TRPS1/KLF4/SRGN/ANKRD1/ADM/EHF/CD44/RND1/NFKBIA/FOS/ANPEP/CSF3/C3/ZFP36/THBD/CEBPB/MYH9/SAT1/IL13RA1 | 38 |
| NAKAMURA_ADIPOGENESIS_EARLY_DN | NAKAMURA_ADIPOGENESIS_EARLY_DN | NAKAMURA_ADIPOGENESIS_EARLY_DN | 18/1438 | 35/23056 | 0.5142857 | 8.245738 | 11.063915 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/VCAM1/ACTG2/SERPINE2/RAI14/HAPLN1/EDIL3/NT5E/THBS2/SERPINE1/TNFRSF11B/PRSS23/GLIPR1/POSTN/TPM1/ITGA3/GDF15/COL9A3 | 18 |
| GOBP_RESPONSE_TO_BMP | GOBP_RESPONSE_TO_BMP | GOBP_RESPONSE_TO_BMP | 40/1438 | 173/23056 | 0.2312139 | 3.707140 | 9.217890 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/HJV/TGFB2/CRIM1/BMP10/DLX1/PPARG/WNT5A/FSTL1/HES1/KDR/LEF1/ADAMTS12/FST/FOXD1/BMP6/HFE/RUNX2/BMPER/FZD1/SULF1/GDF6/EXT1/CRB2/NOTCH1/DKK1/HTRA1/BMP4/FBN1/RBPMS2/SMAD6/ITGA3/NOG/SOX9/GATA6/FSTL3/GDF15/TGFB1/BMP2/GATA5 | 40 |
| GOBP_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 33/1438 | 122/23056 | 0.2704918 | 4.336898 | 9.530971 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/CSF1/S100A10/NID1/VIT/FN1/COL8A1/CCDC80/KDR/NPNT/DAB2/EDIL3/RREB1/UTRN/CD36/COL26A1/PLEKHA2/HAS2/TEK/NRP1/PTPRJ/EFEMP2/APOA1/ITGA5/CDH13/FOXF1/CCR7/JUP/ITGA3/RRAS/RIN2/SDC4/PDGFB | 33 |
| GOBP_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | GOBP_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | GOBP_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | 34/1438 | 129/23056 | 0.2635659 | 4.225852 | 9.475888 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/CD34/AGT/WNT5A/PRICKLE2/GDNF/DAB2/EDN1/RUNX2/RSPO3/CITED2/PDGFA/FZD1/SHH/SULF1/FZD6/CTHRC1/RSPO2/TNFRSF11B/DKK1/WT1/BMP4/DACT1/SIX1/SIX4/SOX8/LHX1/HOXB7/NOG/SOX9/BMP2/GATA5/CELSR1/GPC4 | 34 |
| WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM | WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM | WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM | 23/1438 | 60/23056 | 0.3833333 | 6.146129 | 10.294005 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/CRIM1/RARB/SLIT2/FAT4/GDNF/FST/FOXC1/BMPER/GLI3/SHH/ITGA8/FGFR2/WT1/GLI1/GRIP1/FREM2/BMP4/SIX1/SALL1/LHX1/BMP2/CELSR1 | 23 |
| OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | 46/1438 | 222/23056 | 0.2072072 | 3.322232 | 8.966962 | 0.0000000 | 0.0000000 | 0.0000000 | SPSB1/ZC3H12A/CASQ1/PTGS2/NR5A2/IL1A/IL1B/CXCL8/CXCL1/CXCL3/CXCL2/EREG/ABCG2/LEF1/DAB2/PLK2/TFAP2A/IER3/RHAG/TNFAIP3/SOD2/IL6/FLNC/CA1/KLF4/AKR1C3/CD44/SLCO2B1/BIRC3/C3AR1/AMIGO2/NFKBIA/ZFP36L1/FOS/EPB42/FBN1/BCL2A1/ACSM3/KCNJ2/SERPINB2/GADD45B/ICAM1/KLF2/ZFP36/RUNX1/IL2RB | 46 |
| GOBP_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | GOBP_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | GOBP_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | 42/1438 | 190/23056 | 0.2210526 | 3.544221 | 9.082193 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/TNFSF18/PTPRC/AGT/TGFA/EPHA4/PARP14/HES1/FGFR3/DOK7/TEC/EPGN/EREG/BTC/EGF/IL15/IL31RA/TSLP/CSF2/HBEGF/BMP6/IL6/CD36/ANGPT1/NRP1/CD44/PTPRJ/TNFRSF1A/ITGA5/IGF1/FLT3/EHD4/CSPG4/CTF1/CCL5/CSF3/PECAM1/TGFB1/IL11/PRNP/LIF/PDGFB | 42 |
| WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING_PATHWAY | WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING_PATHWAY | WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING_PATHWAY | 56/1438 | 309/23056 | 0.1812298 | 2.905726 | 8.698249 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CSF1/ITGA10/LAMC2/LAMB3/ITGB6/ITGA6/ITGA4/COL3A1/COL5A2/FN1/LAMB2/ITGB5/FGFR3/KDR/SPP1/EGF/PDGFC/VEGFC/IL7R/OSMR/ITGA2/FGF18/LAMA4/LAMA2/THBS2/PDGFA/ITGB8/MET/FGF20/ANGPT1/TEK/COL5A1/ITGA8/FGFR2/CREB3L1/VWF/ITGA5/ITGA7/IGF1/FLT1/FOXO1/THBS1/ITGA11/IL4R/CSF3/GNGT2/ITGA3/COL1A1/ITGB4/CREB3L3/COL6A2/IL2RB/PDGFB/LPAR4/COL4A6 | 56 |
| GOBP_FORMATION_OF_PRIMARY_GERM_LAYER | GOBP_FORMATION_OF_PRIMARY_GERM_LAYER | GOBP_FORMATION_OF_PRIMARY_GERM_LAYER | 33/1438 | 123/23056 | 0.2682927 | 4.301639 | 9.469038 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/LAMB3/ITGA4/COL5A2/FN1/COL7A1/WNT5A/COL8A1/ITGB5/LEF1/ITGA2/FOXC1/COL12A1/GJA1/INHBA/KLF4/CRB2/COL5A1/ITGA8/DKK1/FGFR2/ITGA5/ITGA7/HMGA2/MMP14/BMP4/MMP2/FOXF1/LHX1/ITGA3/NOG/ITGB4/GATA6 | 33 |
| KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | 33/1438 | 123/23056 | 0.2682927 | 4.301639 | 9.469038 | 0.0000000 | 0.0000000 | 0.0000000 | TMEM158/SEL1L3/CXCL8/SLC7A11/IL7R/PLK2/GFPT2/GPNMB/SERPINE1/CAV2/PTPRZ1/PODXL/AKR1B10/PTN/STC1/MYBL1/FABP4/AKR1C3/DKK1/ANKRD1/ADM/CRYAB/THBS1/NUPR1/MT2A/MT1X/WIPI1/GDF15/IL11/HMOX1/NDP/SPANXB1/SPANXA1 | 33 |
| LIU_SMARCA4_TARGETS | LIU_SMARCA4_TARGETS | LIU_SMARCA4_TARGETS | 21/1438 | 50/23056 | 0.4200000 | 6.734019 | 10.468341 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/CSF1/CD53/ECM1/S100A13/COL3A1/SPARC/ITPR3/PODXL/IFITM2/AHNAK/CRYAB/TAGLN/GPRC5A/IGF1/IL32/NUPR1/MMP2/LPCAT2/GDF15/BCAM | 21 |
| GOBP_EPITHELIAL_TUBE_MORPHOGENESIS | GOBP_EPITHELIAL_TUBE_MORPHOGENESIS | GOBP_EPITHELIAL_TUBE_MORPHOGENESIS | 58/1438 | 328/23056 | 0.1768293 | 2.835171 | 8.633503 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/CSF1/TGFB2/AGT/OSR1/EPHA4/TGFBR2/WNT5A/HES1/SLIT2/KDR/NPNT/LEF1/EGF/IRX2/ADAMTS16/ADAMTS12/GDNF/FOXD1/EDN1/DDR1/GJA1/CITED2/GLI3/FZD1/MET/PODXL/SHH/FZD6/CTHRC1/RSPO2/EXT1/NOTCH1/NRP1/MMRN2/FGFR2/ADM/MICAL2/WT1/PGR/YAP1/MMP14/NFATC4/BMP4/SIX1/SIX4/SOX8/SALL1/FOXF1/LHX1/HOXB7/NOG/SOX9/TGFB1/BMP2/SDC4/CELSR1 | 58 |
| BROWNE_HCMV_INFECTION_24HR_DN | BROWNE_HCMV_INFECTION_24HR_DN | BROWNE_HCMV_INFECTION_24HR_DN | 36/1438 | 145/23056 | 0.2482759 | 3.980701 | 9.286128 | 0.0000000 | 0.0000000 | 0.0000000 | MTMR11/S100A10/CRIM1/COL5A2/CPS1/COL6A3/TGFBR2/COL8A1/CTSO/SEMA5A/ITGA2/LAMA4/PDE1C/SEMA3C/CAV1/MEST/ANGPT1/EXT1/TPM2/COL13A1/DNMBP/CD44/PAMR1/PRSS23/MMP1/VWA5A/THBS1/FBN1/CA12/ACSM3/CDH13/MYH8/ABCA8/SLC14A1/RIN2/MXRA5 | 36 |
| IGLESIAS_E2F_TARGETS_UP | IGLESIAS_E2F_TARGETS_UP | IGLESIAS_E2F_TARGETS_UP | 36/1438 | 145/23056 | 0.2482759 | 3.980701 | 9.286128 | 0.0000000 | 0.0000000 | 0.0000000 | GBP4/CD53/CTSS/S100A10/S100A11/S100A13/CD34/COL3A1/COL5A2/COL6A3/ANXA3/DAB2/SPARC/LAMA4/GJA1/CA3/GSN/SERPINH1/EMP1/LUM/POSTN/LCP1/NFKBIA/NID2/CRIP1/ANXA2/CES1/KRT19/COL1A1/C3/APOE/COL18A1/COL6A2/LGALS1/SAT1/ITM2A | 36 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_CELL_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_CELL_ACTIVATION | 45/1438 | 216/23056 | 0.2083333 | 3.340287 | 8.912556 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ZC3H12A/PTPN22/ILDR2/PTPRC/LAX1/SERPINE2/BCL6/IL31RA/HFE/MICA/ADGRF5/TNFRSF21/TNFAIP3/PDGFA/GPNMB/INHBA/GLI3/SHH/IDO1/CD274/PDCD1LG2/ANXA1/SFTPD/TSPAN32/LRRC32/UBASH3B/NCKAP1L/LRFN5/BMP4/IL4R/ADAMTS18/FOXF1/MILR1/C1QTNF1/AXL/APOE/IL4I1/PRNP/THBD/SDC4/CEBPB/RUNX1/HMOX1/PDGFB | 45 |
| DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | 28/1438 | 91/23056 | 0.3076923 | 4.933348 | 9.696255 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/EFEMP1/IL1R1/KYNU/ITGB6/TFPI/MME/NPNT/GALNT10/RNF144B/CRYBG1/UTRN/TNS3/TSPAN12/ATP6V0A4/ZNF467/S1PR3/RND1/DRAM1/NUAK1/HCAR1/DNAJC15/AHNAK2/BMF/UACA/CDYL2/CRISPLD2/GRB7 | 28 |
| CROONQUIST_STROMAL_STIMULATION_UP | CROONQUIST_STROMAL_STIMULATION_UP | CROONQUIST_STROMAL_STIMULATION_UP | 22/1438 | 56/23056 | 0.3928571 | 6.298828 | 10.239156 | 0.0000000 | 0.0000000 | 0.0000000 | COL6A3/CXCL1/CXCL3/CXCL2/TGFBI/SPARC/IER3/LAMA4/CCN2/THBS2/IL6/SERPINE1/SULF1/TPM2/MYOF/MICAL2/NNMT/LUM/NFKBIA/FOS/NUPR1/TGM2 | 22 |
| BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | 20/1438 | 46/23056 | 0.4347826 | 6.971035 | 10.455010 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/EPHA2/LBH/SEMA3B/F2RL1/RREB1/TPD52L1/THBS2/SERPINE1/COL5A1/BMP4/SMAD6/TNFRSF12A/ITGA3/SOX9/ITGB4/GADD45B/CD70/IL11/CARD10 | 20 |
| GOBP_BONE_DEVELOPMENT | GOBP_BONE_DEVELOPMENT | GOBP_BONE_DEVELOPMENT | 45/1438 | 218/23056 | 0.2064220 | 3.309643 | 8.836866 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/PTPRC/SRD5A2/CYP26B1/ITGB6/COL3A1/RARB/TGFBR2/FGFR3/KDR/PDGFC/ADAMTS12/FGF18/FOXC1/BMP6/TFAP2A/RUNX2/GJA1/CITED2/FAM20C/GLI3/CSGALNACT1/STC1/SULF1/EXT1/HAS2/CCN4/COL27A1/COL13A1/PAPSS2/FGFR2/SERPINH1/EPYC/IGF1/MMP14/BMP4/FBN1/ANXA2/COL1A1/SOX9/SIGLEC15/BMP2/TGM2/PLS3/BGN | 45 |
| GOCC_CELL_CELL_JUNCTION | GOCC_CELL_CELL_JUNCTION | GOCC_CELL_CELL_JUNCTION | 75/1438 | 497/23056 | 0.1509054 | 2.419524 | 8.251165 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/NEXN/CD53/S100A11/ILDR2/HMCN1/CCDC85A/VAMP5/DPP4/MPP4/DES/EPHA4/HEG1/AMOTL2/CLDN1/CLDN16/FGFRL1/AMTN/ARHGAP24/CDH9/DSP/GJA1/PTPRK/PERP/MICALL2/PODXL/ZYX/PDLIM2/EPPK1/TEK/DDX58/B4GALT1/AQP7/AQP3/ANXA1/CRB2/NOTCH1/JCAD/COL13A1/VCL/DNMBP/PTPRJ/AHNAK/FZD4/HEPACAM/KCNA5/YBX3/RND1/KRT18/ITGA5/TRPC4/AJUBA/PRKD1/FRMD6/CGNL1/MYO1E/ANXA2/CLDN6/LAT/KIFC3/CLDN7/MYH1/MYH2/JUP/SGCA/PECAM1/KCNJ2/DSG2/CNN2/WTIP/SCN1B/NECTIN2/MYH9/CDC42EP1/MSN | 75 |
| GOBP_REGULATION_OF_WOUND_HEALING | GOBP_REGULATION_OF_WOUND_HEALING | GOBP_REGULATION_OF_WOUND_HEALING | 34/1438 | 133/23056 | 0.2556391 | 4.098759 | 9.243408 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/FAP/TFPI/SERPINE2/PHLDB2/MYLK/CLDN1/F2RL1/HBEGF/RREB1/ADTRP/EDN1/CD109/TNFAIP3/PDGFA/CD36/SERPINE1/CAV1/PLAT/CCN4/EPPK1/ANXA1/ALOX5/MYOZ1/PLAU/UBASH3B/THBS1/TNFRSF12A/ADAMTS18/C1QTNF1/SERPINB2/APOE/THBD/PDGFB | 34 |
| GOBP_SKELETAL_SYSTEM_MORPHOGENESIS | GOBP_SKELETAL_SYSTEM_MORPHOGENESIS | GOBP_SKELETAL_SYSTEM_MORPHOGENESIS | 46/1438 | 227/23056 | 0.2026432 | 3.249055 | 8.782614 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/TBX15/PRRX1/OSR1/CYP26B1/DLX2/COL3A1/RARB/TGFBR2/FGFR3/NKX3-2/FGF18/FOXC1/BMP6/TFAP2A/MDFI/RUNX2/CCN2/CITED2/HOXA1/HOXA2/HOXA3/HOXA7/GLI3/CSGALNACT1/STC1/EXT1/HAS2/COL27A1/COL13A1/FGFR2/ALX4/SERPINH1/WNT10B/MMP14/BMP4/SIX1/SIX4/MMP2/LHX1/HOXB2/HOXB3/HOXB7/COL1A1/NOG/SOX9 | 46 |
| WP_IL18_SIGNALING_PATHWAY | WP_IL18_SIGNALING_PATHWAY | WP_IL18_SIGNALING_PATHWAY | 52/1438 | 279/23056 | 0.1863799 | 2.988300 | 8.617674 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/PTGS2/PTPN7/IL1B/COL3A1/CASP8/FN1/DES/IL17RC/PLD1/CLDN1/CXCL8/CXCL3/CXCL2/SPP1/TNIP3/IER3/RUNX2/PLA2G7/TNFAIP3/IL6/CD36/PTPRZ1/TNFRSF11B/CCN4/TRAF1/FAS/NFKB2/BIRC3/MMP1/MMP3/TNFRSF1A/EPS8/MMP14/NFATC4/NFKBIA/FOS/TNFAIP2/MMP2/CETP/KIFC3/CCL5/COL1A1/SOCS3/ICAM1/KLF2/BMP2/TGM2/SDC4/CEBPB/ADAMTS5/HMOX1 | 52 |
| GOBP_REGULATION_OF_LEUKOCYTE_MIGRATION | GOBP_REGULATION_OF_LEUKOCYTE_MIGRATION | GOBP_REGULATION_OF_LEUKOCYTE_MIGRATION | 45/1438 | 219/23056 | 0.2054795 | 3.294530 | 8.799349 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/EDN2/CSF1/ECM1/TNFSF18/IL1R1/IL1A/DPP4/ITGA4/WNT5A/SLIT2/CXCL8/VEGFC/ITGA2/F2RL1/ADTRP/EDN1/GPSM3/PLA2G7/IL6/HOXA7/SERPINE1/PTN/RARRES2/ANXA1/C3AR1/KLRC4-KLRK1/NCKAP1L/MMP14/BDKRB1/THBS1/CYP19A1/CCL5/CCR7/ELANE/TNFSF14/ICAM1/IL27RA/PLVAP/C5AR1/DEFB124/HMOX1/RAC2/XG/MSN | 45 |
| GOBP_VASCULOGENESIS | GOBP_VASCULOGENESIS | GOBP_VASCULOGENESIS | 26/1438 | 80/23056 | 0.3250000 | 5.210848 | 9.730421 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/CD34/ACKR3/TGFBR2/HEG1/KDR/CITED2/ITGB8/CAV1/SHH/ZFPM2/HAS2/NOTCH1/ADM/WT1/FZD4/YAP1/ZFP36L1/MYO1E/FOXF1/MYOCD/TGFB1/RRAS/RIN2/WNT7B | 26 |
| GOBP_MESENCHYMAL_CELL_DIFFERENTIATION | GOBP_MESENCHYMAL_CELL_DIFFERENTIATION | GOBP_MESENCHYMAL_CELL_DIFFERENTIATION | 48/1438 | 246/23056 | 0.1951220 | 3.128464 | 8.656165 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/OSR1/IL1B/NRP2/FN1/EPHA4/TGFBR2/SEMA3B/WNT5A/EPHA3/PHLDB2/WWTR1/HES1/LEF1/SEMA5A/GDNF/DAB2/FOXC1/EDN1/CITED2/IL6/SEMA3C/SEMA3A/SEMA3D/SHH/LOXL2/ZNF703/EXT1/HAS2/CRB2/NOTCH1/NRP1/TCF7L2/FGFR2/BCL9L/HMGA2/EDNRB/BMP4/SIX1/ALDH1A2/SOX8/COL1A1/NOG/SOX9/SEMA6B/TGFB1/BMP2/GATA5 | 48 |
| MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_DEPENDENT_BLOCKED_BY_FZD8CRD | MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_DEPENDENT_BLOCKED_BY_FZD8CRD | MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_DEPENDENT_BLOCKED_BY_FZD8CRD | 20/1438 | 47/23056 | 0.4255319 | 6.822715 | 10.305755 | 0.0000000 | 0.0000000 | 0.0000000 | IL1R1/LYPD1/COL3A1/COL5A2/PRICKLE2/LEF1/NKD2/HAPLN1/RBM24/SEMA3C/SERPINE1/CLIC3/PAMR1/EPYC/LUM/LCP1/CRISPLD2/NOG/KLHL4/SRPX2 | 20 |
| JINESH_BLEBBISHIELD_VS_LIVE_CONTROL_DN | JINESH_BLEBBISHIELD_VS_LIVE_CONTROL_DN | JINESH_BLEBBISHIELD_VS_LIVE_CONTROL_DN | 55/1438 | 308/23056 | 0.1785714 | 2.863103 | 8.489752 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/IFI44L/GBP2/GBP4/LAMC2/CFH/IKBKE/HNMT/KYNU/SP110/IRAK2/TGFBR2/TMEM158/UBA7/ARL14/SLC4A4/CXCL1/SNCAIP/SERPINB1/EDN1/NT5E/SOD2/SAMD9/PODXL/TPK1/ANXA8/IFITM2/IFITM3/CD44/PLAAT4/MMP10/CASP4/CASP1/TAGLN/MPZL2/C1RL/NUAK1/OASL/IRF9/PYGL/ANXA2/CA12/SMAD6/IL32/KRT17/IFI35/SLC16A5/LIPG/SERPINB8/C3/S1PR5/RIN2/MX2/MX1/SAT1 | 55 |
| WP_PI3KAKT_SIGNALING_PATHWAY | WP_PI3KAKT_SIGNALING_PATHWAY | WP_PI3KAKT_SIGNALING_PATHWAY | 59/1438 | 345/23056 | 0.1710145 | 2.741940 | 8.407733 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CSF1/ITGA10/LAMC2/LAMB3/TGFA/ITGB6/ITGA6/ITGA4/FN1/COL6A3/LAMB2/ITGB5/FGFR3/KDR/FGF5/SPP1/EGF/PDGFC/VEGFC/IL7R/OSMR/ITGA2/FGF18/LAMA4/LAMA2/THBS2/PDGFA/ITGB8/IL6/MET/FGF20/ANGPT1/TEK/ITGA8/FGFR2/CREB3L1/VWF/ITGA5/ITGA7/IGF1/FLT3/FLT1/THBS1/ITGA11/IL4R/CSF3/GNGT2/ITGA3/COL1A1/ITGB4/CREB3L3/COL9A3/COL6A2/IL2RB/PDGFB/LPAR4/COL4A6/COL4A5 | 59 |
| HALLMARK_IL6_JAK_STAT3_SIGNALING | HALLMARK_IL6_JAK_STAT3_SIGNALING | HALLMARK_IL6_JAK_STAT3_SIGNALING | 27/1438 | 87/23056 | 0.3103448 | 4.975877 | 9.582431 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/CSF1/IL1R1/IL1B/ITGA4/CXCL1/CXCL3/PDGFC/OSMR/CSF2/TNFRSF21/IL6/CD36/IL15RA/MAP3K8/FAS/CD44/TNFRSF1A/IRF9/TNFRSF12A/IL4R/SOCS3/EBI3/IL12RB1/TGFB1/HMOX1/IL13RA1 | 27 |
| RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | 66/1438 | 412/23056 | 0.1601942 | 2.568454 | 8.285106 | 0.0000000 | 0.0000000 | 0.0000000 | HSD11B1/NLRP3/CRIM1/IL1A/IL1B/KYNU/SP110/SP140L/MITF/SLC12A8/RBM47/CXCL1/CXCL5/CXCL3/EREG/SPP1/TNIP3/SLC7A11/C9/IQGAP2/HBEGF/CCDC69/SPARC/HLA-E/PLA2G7/VNN1/SOD2/GPNMB/TNS3/SERPINE1/ADAM28/IDO1/ST3GAL1/NRP1/ALOX5/MYOF/TCF7L2/IFITM2/NRIP3/MS4A4A/PLAAT4/CASP1/VWA5A/C1S/C3AR1/EMP1/BHLHE41/CPM/RAB20/SLC7A7/LTBP2/MMP2/CES1/MT2A/MT1X/NQO1/ABCC3/PECAM1/C3/APOE/C5AR1/FPR1/RIN2/TGM2/MX2/NDP | 66 |
| GILDEA_METASTASIS | GILDEA_METASTASIS | GILDEA_METASTASIS | 16/1438 | 29/23056 | 0.5517241 | 8.846003 | 10.903929 | 0.0000000 | 0.0000000 | 0.0000000 | GBP1/IFI16/VAMP5/HNMT/COL5A2/FN1/SPARC/AKR1C3/SRGN/TAGLN/MPZL2/ARHGDIB/GLIPR1/KRT19/MYL9/RAC2 | 16 |
| GOBP_T_CELL_PROLIFERATION | GOBP_T_CELL_PROLIFERATION | GOBP_T_CELL_PROLIFERATION | 43/1438 | 205/23056 | 0.2097561 | 3.363099 | 8.765174 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF4/TNFRSF1B/VCAM1/PTPN22/TNFSF18/PTPRC/IL1A/IL1B/TGFBR2/HES1/IL15/DOCK2/HLA-E/TNFRSF21/GJA1/IL6/GPNMB/SHH/IDO1/CD274/PDCD1LG2/ANXA1/SFTPD/LRRC32/NCKAP1L/IGF1/TNFSF13B/BMP4/PSMB10/CCL5/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/IL4I1/PRNP/SDC4/CEBPB/ICOSLG/RAC2/MSN | 43 |
| PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | 25/1438 | 75/23056 | 0.3333333 | 5.344460 | 9.719327 | 0.0000000 | 0.0000000 | 0.0000000 | S100A2/TGFA/ITGB6/TFPI/NABP1/PHLDB2/MGLL/WWTR1/TMEM156/F2RL1/NT5E/MET/LOXL2/STC1/ADAM9/COL13A1/ANKRD22/CD44/MMP1/ITGA5/BCL2A1/CAVIN1/FSTL3/IL11/ZNF185 | 25 |
| GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN | 28/1438 | 94/23056 | 0.2978723 | 4.775900 | 9.460930 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/IFI16/PTPRC/IL1B/TFPI/TM4SF1/CXCL8/CXCL6/CXCL1/CXCL3/CXCL2/CTSO/CRHBP/TPBG/VNN1/ADGRG6/SOD2/INHBA/ADAM28/RBPMS/AKR1C3/ALOX5/TCF7L2/CD44/BIRC3/MPZL2/EMP1/GLIPR1 | 28 |
| GOBP_REGULATION_OF_RESPONSE_TO_WOUNDING | GOBP_REGULATION_OF_RESPONSE_TO_WOUNDING | GOBP_REGULATION_OF_RESPONSE_TO_WOUNDING | 38/1438 | 166/23056 | 0.2289157 | 3.670292 | 8.905209 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/FAP/TFPI/EPHA4/SERPINE2/PHLDB2/MYLK/CLDN1/SPP1/F2RL1/HBEGF/RREB1/ADTRP/EDN1/CD109/TNFAIP3/PDGFA/CD36/SERPINE1/CAV1/PTN/PLAT/CCN4/EPPK1/ANXA1/KLF4/ALOX5/MYOZ1/PLAU/UBASH3B/THBS1/TNFRSF12A/ADAMTS18/C1QTNF1/SERPINB2/APOE/THBD/PDGFB | 38 |
| GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | 23/1438 | 64/23056 | 0.3593750 | 5.761996 | 9.838862 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/CRIM1/EFEMP1/NRP2/EPHA4/EPHA3/FGFRL1/FGFR3/KDR/DDR1/ROS1/EPHB4/MET/EPHB6/PDGFRL/TEK/NRP1/FGFR2/FLT3/FLT1/LTK/AXL | 23 |
| TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_UP | 24/1438 | 70/23056 | 0.3428571 | 5.497159 | 9.718736 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/PRRX1/COL3A1/COL5A2/FN1/COL6A3/COL8A1/LRRC15/SPARC/COL12A1/THBS2/INHBA/SULF1/CTHRC1/CCN4/COL5A1/MICAL2/IGF1/POSTN/FBN1/COL1A1/C5AR1/MXRA5/BGN | 24 |
| GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 39/1438 | 175/23056 | 0.2228571 | 3.573153 | 8.812546 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/PTGS2/TGFB2/AGT/NRP2/TGFBR2/WNT5A/KDR/ANXA3/EGF/VEGFC/SEMA5A/ITGA2/PLK2/HBEGF/SPARC/FGF18/RREB1/EDN1/SASH1/MET/ADAM9/ANGPT1/HAS2/TEK/ANXA1/JCAD/NRP1/PRKD1/BMP4/THBS1/ITGA3/SOX9/TGFB1/RRAS/RIN2/HMOX1/PDGFB/SRPX2 | 39 |
| GOBP_OSTEOBLAST_DIFFERENTIATION | GOBP_OSTEOBLAST_DIFFERENTIATION | GOBP_OSTEOBLAST_DIFFERENTIATION | 47/1438 | 241/23056 | 0.1950207 | 3.126842 | 8.560275 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CCN1/CRIM1/TWIST2/PPARG/WWTR1/OSTN/BMP3/SPP1/NPNT/LEF1/VEGFC/BMP6/ID4/RUNX2/TENT5A/GJA1/FAM20C/IL6/HOXA2/GLI3/FZD1/SHH/CEBPD/CTHRC1/RSPO2/CCN4/NOTCH1/FGFR2/CREB3L1/YAP1/WNT10B/GLI1/IGF1/PRKD1/BMP4/SMAD6/ITGA11/SOX8/COL1A1/NOG/MRC2/SOX9/BMP2/CEBPB/CYP24A1/WNT7B | 47 |
| PILON_KLF1_TARGETS_UP | PILON_KLF1_TARGETS_UP | PILON_KLF1_TARGETS_UP | 74/1438 | 497/23056 | 0.1488934 | 2.387264 | 8.063648 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/VCAM1/RHOC/LGR6/IL1B/ITGA4/COL3A1/COL5A2/CAVIN2/NRP2/FN1/MLPH/TMEM158/ITIH3/FSTL1/MYLK/AADAC/LPP/FAM114A1/ABCG2/CFI/GYPA/DAB2/ELL2/LECT2/SPARC/SLC22A23/CAP2/HLA-E/OGFRL1/FAM126A/FZD1/FOXP2/PODXL/AKR1B10/MSR1/LOXL2/CLU/ASPH/FABP4/CA1/COL14A1/LOXL4/FGFR2/SERPINH1/APOA1/MPZL2/VWF/C1S/SLC38A4/DNAJC22/KRT8/LUM/FLT1/EDNRB/NID2/PLEK2/SERPINA10/SERPINA6/EPB42/RHBDF1/COL1A1/ABCC3/ABCA8/GATA6/LIPG/MYL9/COL18A1/COL6A2/GAS2L1/HMOX1/ITM2A/PRRG3/BGN | 74 |
| MARKEY_RB1_CHRONIC_LOF_DN | MARKEY_RB1_CHRONIC_LOF_DN | MARKEY_RB1_CHRONIC_LOF_DN | 32/1438 | 123/23056 | 0.2601626 | 4.171286 | 9.095189 | 0.0000000 | 0.0000000 | 0.0000000 | CD53/CTSS/IFI16/CFH/PTPRC/TGFB2/ACTG2/TFPI/STAB1/PLSCR2/TEC/PLAC8/NPR3/SLC22A23/EDN1/PLA2G7/TPD52L1/IL6/SKAP2/UPK3B/MEST/MSR1/CA3/CCN4/SRGN/HTRA1/C3AR1/KRT18/NUPR1/TRPV2/APOE/HMOX1 | 32 |
| EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 42/1438 | 200/23056 | 0.2100000 | 3.367010 | 8.671000 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA6/CASP10/DES/COL6A3/HRH1/RARB/TNNC1/WWTR1/INPP4B/MYO10/HSPB3/HBEGF/ABLIM3/SERPINB1/TPD52L1/UTRN/CD36/GPR37/ATP6V0A4/PNOC/PYGM/EHBP1L1/CRYAB/TAGLN/C1R/TNFAIP2/AHNAK2/ALDH1A2/TPM1/IL32/CTF1/MYH8/MYH1/CAVIN1/MYL4/COL1A1/MYOM1/GADD45B/TGM2/LIF/SMPX/ARHGEF6 | 42 |
| HALLMARK_ESTROGEN_RESPONSE_EARLY | HALLMARK_ESTROGEN_RESPONSE_EARLY | HALLMARK_ESTROGEN_RESPONSE_EARLY | 42/1438 | 200/23056 | 0.2100000 | 3.367010 | 8.671000 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/OLFML3/ELF3/CYP26B1/MLPH/BHLHE40/SEMA3B/HES1/FOXC1/MICB/TPBG/GJA1/TPD52L1/PODXL/MYBL1/B4GALT1/AQP3/KLF4/CLIC3/PAPSS2/MYOF/CD44/PLAAT3/SYT12/ALDH3B1/P2RY2/PRSS23/PGR/SCNN1A/KRT8/KRT18/FOS/CA12/CLDN7/KRT13/KRT15/KRT19/BLVRB/TGM2/TFAP2C/CELSR1/ZNF185 | 42 |
| GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | GOMF_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | 26/1438 | 83/23056 | 0.3132530 | 5.022505 | 9.468495 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/HJV/LTBP1/CRIM1/EFEMP1/NRP2/EPHA4/TGFBR2/EPHA3/FGFRL1/FGFR3/KDR/DDR1/ROS1/EPHB4/MET/EPHB6/PDGFRL/TEK/NRP1/FGFR2/FLT3/FLT1/LTK/AXL | 26 |
| KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM | KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM | KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM | 26/1438 | 83/23056 | 0.3132530 | 5.022505 | 9.468495 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/TGFB2/ITGB6/ITGA6/ITGA4/DES/TNNC1/ITGB5/ITGA2/LAMA2/ITGB8/IL6/TPM2/ITGA8/CACNA2D4/ITGA5/ITGA7/IGF1/ACTC1/TPM1/ITGA11/ITGA3/SGCA/ITGB4/TGFB1/CACNG6 | 26 |
| NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP | 26/1438 | 83/23056 | 0.3132530 | 5.022505 | 9.468495 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/ECM1/FCGR2A/CFH/EFEMP1/KYNU/FAP/MME/DOCK2/THBS2/GPNMB/SERPINE1/CD44/MS4A4A/SLC15A3/NNMT/C1S/NCKAP1L/LUM/SERPINA1/THBS1/IL4R/CCL5/C3/APOL1/SRPX2 | 26 |
| WP_GLUCOCORTICOID_RECEPTOR_PATHWAY | WP_GLUCOCORTICOID_RECEPTOR_PATHWAY | WP_GLUCOCORTICOID_RECEPTOR_PATHWAY | 24/1438 | 71/23056 | 0.3380282 | 5.419734 | 9.619606 | 0.0000000 | 0.0000000 | 0.0000000 | EDN2/PTGS2/CAVIN2/DNER/ACKR3/BHLHE40/PLK2/ADGRF4/TNFAIP3/SRGN/ANKRD1/NFKB2/PRRG4/BIRC3/SCNN1A/AMIGO2/NAV3/ALOX5AP/DNAJC15/ZIC2/MFGE8/GADD45B/IL11/THBD | 24 |
| HP_THICKENED_SKIN | HP_THICKENED_SKIN | HP_THICKENED_SKIN | 66/1438 | 419/23056 | 0.1575179 | 2.525544 | 8.127868 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/FUCA1/NEXN/ECM1/LAMC2/LAMB3/HSD11B1/NLRP3/ITGB6/CCDC141/DES/COL6A3/IL17RC/PPARG/COL7A1/TNNC1/SLCO2A1/CLDN1/FGFR3/VEGFC/IL7R/PCSK1/ADAMTS2/DSP/CAP2/HFE/PSMB8/PSMB9/COL12A1/LAMA4/GJA1/PERP/SASH1/SEMA3A/CAV1/COL14A1/DDX58/MYPN/VCL/ANKRD1/BAG3/FGFR2/CRYAB/LTBP2/FOS/ACTC1/FBN1/CYP19A1/TPM1/MMP2/KRT13/KRT17/JUP/CAVIN1/COL1A1/ITGB4/RHBDF2/DSG2/SERPINB7/SERPINB8/RIN2/COL6A2/IL2RB/PDGFB/ARSL/COL4A5 | 66 |
| REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | 32/1438 | 124/23056 | 0.2580645 | 4.137646 | 9.035415 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/CSF1/LTBP1/EVA1A/FN1/SHISA5/LAMB2/FSTL1/AMTN/ENAM/SPP1/FUCA2/FAM20C/IL6/PAPPA/PRSS23/MMP1/APOA1/IGFBP6/IGF1/BMP4/SERPINA10/SERPINA1/FBN1/MFGE8/MSLN/MMP2/FSTL3/C3/APOE/APOL1/LGALS1 | 32 |
| WP_BURN_WOUND_HEALING | WP_BURN_WOUND_HEALING | WP_BURN_WOUND_HEALING | 30/1438 | 110/23056 | 0.2727273 | 4.372740 | 9.144921 | 0.0000000 | 0.0000000 | 0.0000000 | S100A11/TGFB2/IL1A/IL1B/FN1/FGFR3/KDR/CXCL8/CXCL1/EGF/IL15/TLR3/FST/SPARC/TNFAIP3/IL6/INHBA/KLF4/FGFR2/SERPINH1/MMP1/MMP3/TAGLN/NFKBIA/FBN1/MMP2/COL1A1/CNN2/ICAM1/TGFB1 | 30 |
| GOBP_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | GOBP_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | GOBP_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION | 49/1438 | 261/23056 | 0.1877395 | 3.010098 | 8.423100 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/ERRFI1/TNFSF18/PTPRC/AGT/TGFA/EPHA4/PARP14/HES1/FGFR3/ZFYVE28/DOK7/TEC/EPGN/EREG/BTC/EGF/IL15/PDGFC/IL31RA/TSLP/CSF2/HBEGF/BMP6/PDGFA/IL6/CD36/CAV1/ANGPT1/NRP1/CD44/PTPRJ/TNFRSF1A/GPRC5A/ITGA5/IGF1/FLT3/EHD4/CSPG4/CTF1/CCL5/CSF3/PECAM1/SOCS3/TGFB1/IL11/PRNP/LIF/PDGFB | 49 |
| LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE | LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE | LINDGREN_BLADDER_CANCER_HIGH_RECURRENCE | 20/1438 | 49/23056 | 0.4081633 | 6.544237 | 10.019915 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/PRRX1/COL5A2/NRP2/MYLK/IL7R/SPARC/ADAM19/LAMA4/PAPPA/MICAL2/SERPINH1/BIRC3/NID2/CRIP1/IL32/MYL9/COL18A1/LGALS1/MSN | 20 |
| NABA_COLLAGENS | NABA_COLLAGENS | NABA_COLLAGENS | 19/1438 | 44/23056 | 0.4318182 | 6.923505 | 10.143367 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/COL21A1/COL19A1/COL12A1/COL26A1/COL14A1/COL27A1/COL5A1/COL13A1/COL1A1/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 19 |
| REACTOME_COLLAGEN_CHAIN_TRIMERIZATION | REACTOME_COLLAGEN_CHAIN_TRIMERIZATION | REACTOME_COLLAGEN_CHAIN_TRIMERIZATION | 19/1438 | 44/23056 | 0.4318182 | 6.923505 | 10.143367 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/COL21A1/COL19A1/COL12A1/COL26A1/COL14A1/COL27A1/COL5A1/COL13A1/COL1A1/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 19 |
| GOBP_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | GOBP_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | GOBP_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA | 49/1438 | 262/23056 | 0.1870229 | 2.998609 | 8.391170 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/TGFB2/LTBP1/ITGB6/DLX1/COL3A1/PPARG/TGFBR2/WNT5A/ITGB5/VEPH1/CLDN1/NPNT/DAB2/EDN1/CD109/PTPRK/CITED2/PDGFA/ITGB8/CAV2/CAV1/ZYX/ZNF703/HTRA4/ADAM9/ITGA8/ANKRD1/FGFR2/HTRA1/LRRC32/APOA1/BCL9L/LATS2/ZFP36L1/LTBP2/FOS/THBS1/FBN1/SMAD6/MYOCD/ITGA3/COL1A1/SOX9/GDF15/TGFB1/PSG9/BMP2/MXRA5 | 49 |
| LEE_NEURAL_CREST_STEM_CELL_UP | LEE_NEURAL_CREST_STEM_CELL_UP | LEE_NEURAL_CREST_STEM_CELL_UP | 35/1438 | 147/23056 | 0.2380952 | 3.817471 | 8.838313 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/S100A10/S100A11/CRABP2/IFI16/GYPC/FAP/ITGA4/COL3A1/NRP2/MITF/SPP1/NPR3/FST/HAPLN1/TGFBI/TFAP2A/MDFI/MOXD1/ADGRG6/HOXA2/SEMA3C/PODXL/CEBPD/COL14A1/ANXA1/GSN/ZCCHC24/CYP26A1/LUM/POSTN/DACT1/HOXB2/LGALS1/BGN | 35 |
| RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | 62/1438 | 383/23056 | 0.1618799 | 2.595482 | 8.120654 | 0.0000000 | 0.0000000 | 0.0000000 | FBLIM1/S100A2/IL1A/PPP1R1C/NABP1/HRH1/TMEM40/OSBPL10/CDCP1/EREG/SGMS2/INPP4B/CARD6/FST/ELL2/ERAP2/PPIC/HBEGF/GALNT10/DSP/ADGRF4/NT5E/PERP/MAFK/FAM126A/INHBA/CD36/EPPK1/PTGS1/ITPRIP/HTRA1/ADM/CD44/AHNAK/EHBP1L1/RAB38/MMP10/MMP1/CASP4/ADAMTS15/KRT80/IGFBP6/CPM/GLIPR1/TMCC3/FRMD6/AHNAK2/CA12/BNC1/LPCAT2/KRT17/JUP/CAVIN1/METRNL/KCNK6/EHD2/SDCBP2/GAS2L1/CARD10/KDELR3/PLS3/IL13RA1 | 62 |
| LU_AGING_BRAIN_UP | LU_AGING_BRAIN_UP | LU_AGING_BRAIN_UP | 49/1438 | 263/23056 | 0.1863118 | 2.987208 | 8.359391 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/S1PR1/IFI16/CFH/ITPKB/AGT/LTBP1/EFEMP1/TGFBR2/SEMA3B/AMOTL2/TM4SF1/WWTR1/LPP/FGFR3/SLC4A4/ANXA3/MYO10/ID4/DDR1/HCRTR2/GJA1/CAV2/CAV1/PODXL/CEBPD/TNFRSF11B/GSN/ZCCHC24/MYOF/FGFR2/HTRA1/BBOX1/AHNAK/SERPINH1/CRYAB/VWF/NFKBIA/NUPR1/MT2A/PECAM1/WIPI1/SLC14A1/RIN2/TGM2/MLC1/MSN/ITM2A/COL4A5 | 49 |
| CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | 17/1438 | 35/23056 | 0.4857143 | 7.787642 | 10.364422 | 0.0000000 | 0.0000000 | 0.0000000 | LTBP1/COL3A1/COL5A2/COL6A3/TWIST2/CXCL6/NT5E/LAMA2/SEMA3C/S1PR3/COL5A1/LTBP2/FBN1/LOXL1/EMILIN2/COL6A2/BGN | 17 |
| WP_PHOTODYNAMIC_THERAPYINDUCED_NFKB_SURVIVAL_SIGNALING | WP_PHOTODYNAMIC_THERAPYINDUCED_NFKB_SURVIVAL_SIGNALING | WP_PHOTODYNAMIC_THERAPYINDUCED_NFKB_SURVIVAL_SIGNALING | 17/1438 | 35/23056 | 0.4857143 | 7.787642 | 10.364422 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/PTGS2/IL1A/IL1B/CXCL8/CXCL2/CSF2/IL6/NFKB2/BIRC3/MMP1/MMP3/TNFRSF1A/BCL2A1/MMP2/ICAM1/RELB | 17 |
| GOBP_CELLULAR_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | GOBP_CELLULAR_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | GOBP_CELLULAR_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN | 45/1438 | 229/23056 | 0.1965066 | 3.150664 | 8.435681 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/ZC3H12A/GFI1/PTPN22/NLRP3/IL1A/IL1B/IL36G/IRAK2/WNT5A/PLSCR4/SPON2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/TNIP3/CSF2/BMP6/TNFAIP3/SASH1/IL6/CD36/SERPINE1/ADAM9/CD274/PDCD1LG2/ANKRD1/TRIM5/CASP1/CARD16/KLRC4-KLRK1/EDNRB/NFKBIA/CD68/CCL5/CSF3/ZFP36/AXL/TGFB1/SIRPA/DEFB124/CEBPB | 45 |
| GOCC_CONTRACTILE_FIBER | GOCC_CONTRACTILE_FIBER | GOCC_CONTRACTILE_FIBER | 46/1438 | 238/23056 | 0.1932773 | 3.098889 | 8.394471 | 0.0000000 | 0.0000000 | 0.0000000 | TRIM63/SYNC/NEXN/CASQ1/IGFN1/LMOD1/ATP2B4/BMP10/XIRP2/DES/TNNC1/NPNT/MYOZ2/GJA1/MYL7/LMOD2/FLNC/PDLIM2/IDO1/FBXO32/TPM2/MYPN/MYOZ1/SYNPO2L/VCL/ANKRD1/BAG3/AHNAK/CRYAB/KCNA5/ACTC1/TPM1/MMP2/MYH13/MYH8/MYH4/MYH1/MYH2/KRT19/JUP/MYL4/MYOM1/MYL9/JPH2/SDC4/SMPX | 46 |
| WOO_LIVER_CANCER_RECURRENCE_UP | WOO_LIVER_CANCER_RECURRENCE_UP | WOO_LIVER_CANCER_RECURRENCE_UP | 29/1438 | 105/23056 | 0.2761905 | 4.428267 | 9.080771 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/COL6A3/EPHA3/SLIT2/CXCL8/CXCL6/CXCL1/DAB2/DDR1/TPBG/LAMA4/CCN2/PDGFA/SEMA3C/FZD1/CSGALNACT1/EXT1/TPM2/HKDC1/PLAU/FGFR2/CRYAB/BHLHE41/POSTN/CRIP1/COL1A1/SOX9/TGFB1/GPC4 | 29 |
| GOBP_MYELOID_LEUKOCYTE_MIGRATION | GOBP_MYELOID_LEUKOCYTE_MIGRATION | GOBP_MYELOID_LEUKOCYTE_MIGRATION | 45/1438 | 230/23056 | 0.1956522 | 3.136966 | 8.400416 | 0.0000000 | 0.0000000 | 0.0000000 | EDN2/MCOLN2/CSF1/TGFB2/IL1R1/IL1A/IL1B/DPP4/HRH1/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/VEGFC/EDN1/PLA2G7/IL6/CCL26/SERPINE1/ARHGEF5/RARRES2/TRIM55/ANXA1/SFTPD/SAA1/C3AR1/NCKAP1L/FLT1/EDNRB/MMP14/THBS1/CYP19A1/CCL5/CCR7/PECAM1/TNFRSF11A/C5AR1/SIRPA/DEFB124/RAC2/PDGFB/XG | 45 |
| GOBP_GLOMERULUS_DEVELOPMENT | GOBP_GLOMERULUS_DEVELOPMENT | GOBP_GLOMERULUS_DEVELOPMENT | 23/1438 | 67/23056 | 0.3432836 | 5.503996 | 9.522031 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/NID1/OSR1/LAMB2/WWTR1/HES1/FOXC1/PDGFA/PODXL/SULF1/ANGPT1/EXT1/TEK/NOTCH1/WT1/EDNRB/BMP4/MYO1E/LHX1/NOG/PECAM1/SERPINB7/PDGFB | 23 |
| GOBP_SKIN_DEVELOPMENT | GOBP_SKIN_DEVELOPMENT | GOBP_SKIN_DEVELOPMENT | 50/1438 | 274/23056 | 0.1824818 | 2.925799 | 8.270745 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/EPHA2/PTCH2/TCHH/SPRR2F/TGFB2/CYP26B1/IL1A/ITGB6/ITGA6/COL3A1/COL5A2/WNT5A/CLDN1/EREG/ITGA2/FST/ADAMTS2/FOXC1/DSP/CD109/PDGFA/HOXA7/INHBA/MET/SHH/ADAM9/FZD6/EXT1/AQP3/ANXA1/COL5A1/NOTCH1/AKR1C3/DKK1/FGFR2/ALX4/PLAAT4/YAP1/WNT10B/TNFRSF19/ZFP36L1/KRT17/JUP/ITGA3/COL1A1/SOX9/ITGB4/GATA6/ZFP36 | 50 |
| GOBP_STRIATED_MUSCLE_CELL_DIFFERENTIATION | GOBP_STRIATED_MUSCLE_CELL_DIFFERENTIATION | GOBP_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 51/1438 | 283/23056 | 0.1802120 | 2.889408 | 8.248273 | 0.0000000 | 0.0000000 | 0.0000000 | CD53/CASQ1/LMOD1/AGT/BMP10/CYP26B1/DNER/RARB/MYOZ2/EDN1/RBM24/TBX18/CAV2/LMOD2/FLNC/SHH/NOTCH1/DKK1/MYPN/MYOZ1/SYNPO2L/ANKRD1/MYOF/WT1/ADAMTS15/BHLHE41/WNT10B/IGF1/MMP14/BMP4/SIX1/SIX4/ACTC1/TPM1/ALPK3/IL4R/MYLK3/PIEZO1/MYOCD/KRT19/GATA6/ALPK2/TNFSF14/GDF15/TGFB1/EHD2/BMP2/MYL9/NFATC2/ADAMTS5/MYH9 | 51 |
| GOBP_MESONEPHROS_DEVELOPMENT | GOBP_MESONEPHROS_DEVELOPMENT | GOBP_MESONEPHROS_DEVELOPMENT | 28/1438 | 99/23056 | 0.2828283 | 4.534693 | 9.090044 | 0.0000000 | 0.0000000 | 0.0000000 | AGT/OSR1/RARB/HES1/SLIT2/NPNT/ADAMTS16/GDNF/FOXD1/FOXC1/SIM1/BMPER/GLI3/SHH/FGFR2/WT1/BMP4/SIX1/SIX4/SMAD6/SOX8/SALL1/LHX1/HOXB7/NOG/SOX9/BMP2/SDC4 | 28 |
| GOBP_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | GOBP_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | GOBP_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | 45/1438 | 231/23056 | 0.1948052 | 3.123386 | 8.365343 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ZC3H12A/PTGS2/ATP2B4/AGT/BMP10/NRP2/SP100/PPARG/WNT5A/SLIT2/KDR/ANXA3/EGF/VEGFC/SEMA5A/PLK2/SPARC/FGF18/EDN1/SASH1/BMPER/MET/PTN/STC1/ANGPT1/TEK/ANXA1/KLF4/NOTCH1/JCAD/NRP1/MMRN2/PRKD1/BMP4/THBS1/JUP/TGFB1/APOE/RRAS/RIN2/HMOX1/CARD10/PDGFB/SRPX2 | 45 |
| KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | 24/1438 | 74/23056 | 0.3243243 | 5.200015 | 9.333124 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/ITGB6/ITGA6/ITGA4/DES/ITGB5/LEF1/ITGA2/DSP/GJA1/LAMA2/ITGB8/ITGA8/TCF7L2/CACNA2D4/ITGA5/ITGA7/ITGA11/JUP/ITGA3/SGCA/ITGB4/DSG2/CACNG6 | 24 |
| GOBP_ERK1_AND_ERK2_CASCADE | GOBP_ERK1_AND_ERK2_CASCADE | GOBP_ERK1_AND_ERK2_CASCADE | 57/1438 | 341/23056 | 0.1671554 | 2.680066 | 8.061234 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/EPHA2/CCN1/GBP1/PTPN22/PTPRC/AGT/IL1A/IL1B/FN1/EPHA4/ACKR3/FGFR3/KDR/NPNT/EGF/PDGFC/DAB2/F2RL1/FGF18/EDN1/TPBG/ROS1/CCN2/PDGFA/GPNMB/BMPER/CCL26/CD36/ARHGEF5/FGF20/ANGPT1/TEK/NOTCH1/NRP1/FGFR2/NLRP6/CD44/OR2AT4/APOA1/IGF1/BMP4/ZFP36L1/TNFAIP8L3/CCL5/CCR7/SOX9/TNFRSF11A/ICAM1/TGFB1/APOE/C5AR1/RRAS/SIRPA/BMP2/LIF/PDGFB | 57 |
| IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | 29/1438 | 107/23056 | 0.2710280 | 4.345495 | 8.945914 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/PODN/S100A16/ATP2B4/COL5A2/KCNE4/ACKR3/TNNC1/CCDC80/ANXA3/NPR3/DAB2/SLC22A23/LAMA4/TPD52L1/MEST/LOXL2/FBXO32/VCL/SYTL2/CRYAB/IGF1/NUAK1/POSTN/LTBP2/FBN1/CA12/MYH2/PTGIS | 29 |
| BURTON_ADIPOGENESIS_PEAK_AT_2HR | BURTON_ADIPOGENESIS_PEAK_AT_2HR | BURTON_ADIPOGENESIS_PEAK_AT_2HR | 19/1438 | 46/23056 | 0.4130435 | 6.622483 | 9.844712 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/TNFRSF1B/CCN1/PTGS2/ACKR3/CXCL2/IER3/CCN2/IL6/SEMA3C/SERPINE1/CEBPD/KLF4/BAG3/ADM/PHLDA1/FOS/THBS1/ZFP36 | 19 |
| KHETCHOUMIAN_TRIM24_TARGETS_UP | KHETCHOUMIAN_TRIM24_TARGETS_UP | KHETCHOUMIAN_TRIM24_TARGETS_UP | 19/1438 | 46/23056 | 0.4130435 | 6.622483 | 9.844712 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/TGFBR2/SPP1/RAI14/HBEGF/SPARC/PDGFA/SERPINE1/FGFR2/CD44/CASP1/EMP1/KRT18/FOS/COL1A1/ICAM1/TGFB1/TGM2/LGALS1 | 19 |
| AFFAR_YY1_TARGETS_UP | AFFAR_YY1_TARGETS_UP | AFFAR_YY1_TARGETS_UP | 41/1438 | 199/23056 | 0.2060302 | 3.303360 | 8.416527 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TINAGL1/GBP2/CFH/TGFB2/EFEMP1/ITGB6/ACKR3/LAMB2/TNNC1/KDR/TSLP/BMP6/ID4/COL19A1/SIM1/TPD52L1/PERP/TNFRSF10A/EBF2/CLU/ANXA8L1/FAS/ANKRD1/WT1/EHF/CRYAB/FLT1/AJUBA/BMP4/FOS/ACTC1/TPM1/MMP2/MYH1/MYH2/KRT19/MYOM1/ICAM1/S1PR5/TGM2 | 41 |
| GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT_CONFERRING_TENSILE_STRENGTH | GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT_CONFERRING_TENSILE_STRENGTH | GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT_CONFERRING_TENSILE_STRENGTH | 18/1438 | 41/23056 | 0.4390244 | 7.039045 | 9.981802 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/COL21A1/COL19A1/COL12A1/COL14A1/COL27A1/COL5A1/COL13A1/COL1A1/COL9A3/COL18A1/COL6A2/COL4A6/COL4A5 | 18 |
| SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | 36/1438 | 159/23056 | 0.2264151 | 3.630199 | 8.583258 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/DHRS3/CDA/TIE1/FCGR2A/HNMT/EPHA4/BHLHE40/COL7A1/WNT5A/MYLK/CXCL8/TGFBI/HBEGF/SPARC/IER3/PERP/CLU/ALOX5/PLAU/ADM/P2RY2/PRSS23/TNFRSF1A/C3AR1/THBS1/ANPEP/IL21R/ADAP2/SERPINB2/TGFB1/C5AR1/FPR1/THBD/CEBPB/HMOX1 | 36 |
| GOBP_PATTERN_SPECIFICATION_PROCESS | GOBP_PATTERN_SPECIFICATION_PROCESS | GOBP_PATTERN_SPECIFICATION_PROCESS | 69/1438 | 460/23056 | 0.1500000 | 2.405007 | 7.850474 | 0.0000000 | 0.0000000 | 0.0000000 | RNF220/PIFO/OSR1/CYP26B1/DLX1/DLX2/NRP2/DAW1/BHLHE40/TGFBR2/WNT5A/HES1/NKX3-2/LEF1/IRX4/IRX2/DNAH5/GDNF/FST/FOXD1/FOXC1/EDN1/MDFI/TDRD6/TBX18/GJA1/CITED2/HOXA2/HOXA3/HOXA7/GLI3/PKD1L1/SEMA3C/SEMA3A/SHH/STC1/ASPH/EXT1/DMRT2/PCSK5/CRB2/NOTCH1/NRP1/DKK1/HHEX/FGFR2/MICAL2/WT1/ALX4/BHLHE41/GLI1/BMP4/SIX1/ALDH1A2/FOXB1/SMAD6/FOXF1/LHX1/MEOX1/HOXB2/HOXB3/HOXB7/NOG/C3/BMP2/GATA5/SIM2/WNT7B/MID1 | 69 |
| THUM_SYSTOLIC_HEART_FAILURE_UP | THUM_SYSTOLIC_HEART_FAILURE_UP | THUM_SYSTOLIC_HEART_FAILURE_UP | 66/1438 | 430/23056 | 0.1534884 | 2.460937 | 7.887079 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/CD53/CTSS/PRRX1/MR1/PLA2G4A/PTPRC/HNMT/CAVIN2/EPHA4/SERPINE2/HRH1/TGFBR2/VGLL3/EPHA3/PLSCR4/TM4SF1/CXCL2/ARHGAP24/CFI/PDGFC/GASK1B/PLK2/DOCK2/EDN1/ID4/H3C6/CLIC5/NT5E/TRDN/UTRN/SKAP2/TSPAN12/GIMAP2/MSR1/ADAM9/PLAT/NECAB1/CTHRC1/TNFRSF11B/FBXO32/GSN/SRGN/FAS/PPP1R3C/ADM/MS4A4A/CASP1/C1S/C3AR1/ARHGDIB/OASL/ALOX5AP/LCP1/LTBP2/THBS1/LOXL1/MFGE8/GADD45B/PRNP/TGM2/NFATC2/MAP3K7CL/IL2RB/RAC2/SRPX2 | 66 |
| HALLMARK_P53_PATHWAY | HALLMARK_P53_PATHWAY | HALLMARK_P53_PATHWAY | 41/1438 | 200/23056 | 0.2050000 | 3.286843 | 8.377327 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/FUCA1/S100A10/TCHH/PTPN14/TGFA/IL1A/TM4SF1/SLC7A11/PLK2/HBEGF/IER3/TPD52L1/PERP/PDGFA/KLF4/NOTCH1/FAS/PTPRE/EPS8L2/CD82/CASP1/VWA5A/H2AJ/DRAM1/ZFP36L1/FOS/NUPR1/RRAD/CDH13/OSGIN1/KRT17/ITGB4/RHBDF2/TNFSF9/TGFB1/BMP2/PROCR/LIF/HMOX1/SAT1 | 41 |
| GOBP_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | GOBP_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | GOBP_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | 45/1438 | 234/23056 | 0.1923077 | 3.083342 | 8.261254 | 0.0000000 | 0.0000000 | 0.0000000 | S1PR1/TGFB2/AGT/BMP10/XIRP2/RARB/TGFBR2/TNNC1/WNT5A/HEG1/FOXC1/DSP/EDN1/TBX18/GJA1/CITED2/MYL7/FGF20/MSC/ZFPM2/NOTCH1/DKK1/ANKRD1/FGFR2/WT1/YAP1/GLI1/IGF1/BMP4/ACTC1/ALDH1A2/TPM1/HCN4/ALPK3/MYLK3/MYOCD/NOG/GATA6/DSG2/ALPK2/TGFB1/BMP2/JPH2/GATA5/RUNX1 | 45 |
| GOBP_REGULATION_OF_CARTILAGE_DEVELOPMENT | GOBP_REGULATION_OF_CARTILAGE_DEVELOPMENT | GOBP_REGULATION_OF_CARTILAGE_DEVELOPMENT | 23/1438 | 69/23056 | 0.3333333 | 5.344460 | 9.321235 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/WNT9A/EFEMP1/BMP10/RARB/WNT5A/NKX3-2/ADAMTS12/FGF18/BMP6/RUNX2/CCN2/SCIN/GLI3/LOXL2/GDF6/TRPS1/CCN4/BMP4/MAF/NOG/SOX9/BMP2 | 23 |
| JINESH_BLEBBISHIELD_TO_IMMUNE_CELL_FUSION_PBSHMS_DN | JINESH_BLEBBISHIELD_TO_IMMUNE_CELL_FUSION_PBSHMS_DN | JINESH_BLEBBISHIELD_TO_IMMUNE_CELL_FUSION_PBSHMS_DN | 63/1438 | 402/23056 | 0.1567164 | 2.512694 | 7.891251 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/PADI3/IFI44L/CRABP2/IFI16/CFH/SRD5A2/HNMT/KYNU/MLPH/BHLHE40/WNT5A/CXCL8/CXCL1/SNCAIP/IER3/NT5E/SOD2/GPNMB/CADPS2/AKR1B10/CEBPD/C9orf152/AKR1C3/ANXA8/IFITM2/IFITM3/PAMR1/RAB38/MMP10/CASP1/VWF/SCNN1A/SLC38A4/ZIC2/IRF9/ZFP36L1/FOS/TNFAIP2/CA12/SMAD6/KRT13/IFI35/HOXB2/ABCA9/ABCA6/GPRC5C/SERPINB8/MBP/PLIN4/C3/CYP4F11/IL4I1/CDC42EP5/SDCBP2/BMP2/RIN2/THBD/MX2/MX1/APOBEC3G/COL4A6/ARHGEF6 | 63 |
| RUTELLA_RESPONSE_TO_HGF_UP | RUTELLA_RESPONSE_TO_HGF_UP | RUTELLA_RESPONSE_TO_HGF_UP | 65/1438 | 422/23056 | 0.1540284 | 2.469596 | 7.858287 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF4/NIBAN1/HSD11B1/RASGRP3/CRIM1/IL1R1/IL1A/IL1B/KYNU/SP140L/MITF/SLC12A8/MGLL/RBM47/CXCL1/CXCL5/CXCL3/SPP1/TNIP3/SLC7A11/C9/SPARC/PLA2G7/VNN1/SOD2/GPNMB/INHBA/TNS3/SERPINE1/ADAM28/IDO1/ST3GAL1/TRAF1/NRP1/MYOF/NRIP3/RAB38/BIRC3/VWA5A/C1S/C3AR1/EMP1/BHLHE41/CPM/RAB20/LTBP2/ANXA2/IL21R/MMP2/CES1/MT2A/MT1X/NQO1/CCR7/ABCC3/EBI3/C3/LYPD3/NECTIN2/APOE/RIN2/TGM2/SDC4/RUNX1/NDP | 65 |
| SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | 34/1438 | 145/23056 | 0.2344828 | 3.759551 | 8.597153 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/PDZK1IP1/GBP2/IFI16/KYNU/CYBRD1/TFPI/GALNT15/LAMB2/MME/BCL6/CXCL1/CXCL3/SNCAIP/DSP/ROS1/VNN1/TNFAIP3/CITED2/SEMA3C/CLU/FBXO32/AQP3/GAS1/ANXA8L1/IFITM2/IFITM3/BIRC3/C1S/NFKBIA/FOS/KRT13/KRT19/SAT1 | 34 |
| OSADA_ASCL1_TARGETS_DN | OSADA_ASCL1_TARGETS_DN | OSADA_ASCL1_TARGETS_DN | 14/1438 | 24/23056 | 0.5833333 | 9.352805 | 10.559087 | 0.0000000 | 0.0000000 | 0.0000000 | CRIM1/TGFBI/RSPO3/SEMA3C/DKK1/CD44/AHNAK/BIRC3/IGFBP6/BCL2A1/SOCS3/AXL/CYP24A1/WNT7B | 14 |
| BOYLAN_MULTIPLE_MYELOMA_C_D_DN | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | 50/1438 | 280/23056 | 0.1785714 | 2.863103 | 8.089683 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/VCAM1/PTPN22/IFI16/LAX1/HSD11B1/RASGRP3/ITGB5/FNDC3B/RTP4/SGMS2/INPP4B/IQGAP2/F2RL1/ELL2/TGFBI/DSP/HLA-E/RUNX2/TNS3/C7orf57/PON3/MDFIC/ZNF467/AQP3/PTPRE/IFITM3/TRIM5/MS4A4A/PLAAT3/CASP4/KLRD1/KLRC4-KLRK1/PYGL/FOS/ANXA2/ITPRIPL2/MAF/CLDN7/CCL5/WIPI1/SLC16A5/DSG2/ELANE/C3/FPR1/IL2RB/KDELR3/LPAR4/IL13RA1 | 50 |
| GOBP_LEUKOCYTE_CHEMOTAXIS | GOBP_LEUKOCYTE_CHEMOTAXIS | GOBP_LEUKOCYTE_CHEMOTAXIS | 45/1438 | 236/23056 | 0.1906780 | 3.057212 | 8.192785 | 0.0000000 | 0.0000000 | 0.0000000 | EDN2/S1PR1/CSF1/TGFB2/IL1B/DPP4/HRH1/WNT5A/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/VEGFC/F2RL1/EDN1/GPSM3/PLA2G7/IL6/CCL26/SERPINE1/PTN/ARHGEF5/RARRES2/ANXA1/ALOX5/SFTPD/SAA1/C3AR1/KLRC4-KLRK1/NCKAP1L/FLT1/EDNRB/THBS1/CYP19A1/CCL5/CCR7/TNFRSF11A/TNFSF14/C5AR1/DEFB124/RAC2/PDGFB | 45 |
| GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION | GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION | GOBP_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 47/1438 | 254/23056 | 0.1850394 | 2.966807 | 8.129171 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF4/TNFRSF1B/VCAM1/CSF1/PTPN22/TNFSF18/PTPRC/IL1A/IL1B/TGFBR2/BCL6/HES1/IL15/CSF2/MZB1/HLA-E/TNFRSF21/TNFAIP3/AHR/IL6/GPNMB/SHH/IDO1/CD274/PDCD1LG2/ANXA1/SFTPD/HHEX/LRRC32/NCKAP1L/IGF1/TNFSF13B/BMP4/CCL5/EBI3/TNFSF9/CD70/IL27RA/IL12RB1/CD22/IL4I1/PRNP/SDC4/CEBPB/NFATC2/ICOSLG/RAC2 | 47 |
| SANA_RESPONSE_TO_IFNG_UP | SANA_RESPONSE_TO_IFNG_UP | SANA_RESPONSE_TO_IFNG_UP | 24/1438 | 76/23056 | 0.3157895 | 5.063173 | 9.150636 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP3/GBP1/GBP4/CFH/VAMP5/PARP14/DDX60/HLA-E/HLA-C/SAMD9L/ATP6V0A4/IDO1/CD274/PLAAT4/CASP1/C1S/NLRC5/MLKL/IFI35/LIPG/MX1/APOL3/APOL1 | 24 |
| WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY | WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY | WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY | 24/1438 | 76/23056 | 0.3157895 | 5.063173 | 9.150636 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/ITGB6/ITGA6/ITGA4/DES/ITGB5/LEF1/ITGA2/DSP/GJA1/LAMA2/ITGB8/ITGA8/TCF7L2/CACNA2D4/ITGA5/ITGA7/ITGA11/JUP/ITGA3/SGCA/ITGB4/DSG2/CACNG6 | 24 |
| WANG_SMARCE1_TARGETS_DN | WANG_SMARCE1_TARGETS_DN | WANG_SMARCE1_TARGETS_DN | 61/1438 | 385/23056 | 0.1584416 | 2.540354 | 7.860854 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ITGA10/S100A2/TRABD2A/KYNU/CAVIN2/SUSD5/CDCP1/TM4SF18/TM4SF1/SPON2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/FGF5/CFAP299/ARSJ/INPP4B/GASK1B/PLK2/ADAMTS2/MICA/PSMB8/PSMB9/TNFRSF21/PTP4A1/OGFRL1/NT5E/LAMA4/TPD52L1/RSPO3/CITED2/SOD2/SEMA3C/CAV2/CAV1/PARP12/MYBL1/ZFPM2/TNFRSF11B/SRGN/PRSS23/TRPC4/DNAJC15/BDKRB1/EHD4/TPM1/LOXL1/IL4R/CD70/GDF15/TGM2/MX2/MX1/LIF/MXRA5/MID1/MAGEA1 | 61 |
| GOBP_METANEPHROS_DEVELOPMENT | GOBP_METANEPHROS_DEVELOPMENT | GOBP_METANEPHROS_DEVELOPMENT | 26/1438 | 89/23056 | 0.2921348 | 4.683909 | 8.980613 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/OSR1/LAMB2/WWTR1/HES1/IRX2/GDNF/FOXD1/PDGFA/GLI3/SHH/GDF6/ITGA8/WT1/YAP1/BMP4/SIX1/SIX4/FBN1/SOX8/SALL1/LHX1/SOX9/LIF/PDGFB/WNT7B | 26 |
| GOBP_CELL_CELL_SIGNALING_BY_WNT | GOBP_CELL_CELL_SIGNALING_BY_WNT | GOBP_CELL_CELL_SIGNALING_BY_WNT | 68/1438 | 455/23056 | 0.1494505 | 2.396197 | 7.757878 | 0.0000000 | 0.0000000 | 0.0000000 | RNF220/TRABD2B/LGR6/WNT9A/TRABD2A/WNT5A/PRICKLE2/MITF/AMOTL2/WWTR1/LEF1/EGF/NKD2/SEMA5A/DAB2/SOX30/EDN1/MDFI/TPBG/TBX18/RSPO3/TNFAIP3/GLI3/HECW1/FZD1/MDFIC/CAV1/SHH/ZNF703/SULF1/FZD6/CTHRC1/RSPO2/EXT1/CCN4/KLF4/NOTCH1/FZD8/DKK1/HHEX/TCF7L2/FGFR2/FZD4/YAP1/BCL9L/WNT10B/IGFBP6/GLI1/LATS2/FOXO1/EDNRB/NFATC4/DACT1/SALL1/JUP/ITGA3/COL1A1/NOG/SOX9/ALPK2/TGFB1/APOE/BMP2/APCDD1L/WNT7B/CELSR1/NDP/GPC4 | 68 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | 38/1438 | 178/23056 | 0.2134831 | 3.422856 | 8.369180 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/MCOLN2/PTGS2/LBH/LTBP1/FN1/SLC12A8/EREG/CFI/IL31RA/ZNF366/TSLP/ADAM19/PTPRK/TMEM200A/AHR/HOXA3/HOXA7/IDO1/S1PR3/ANKRD22/HBD/WT1/TESPA1/METTL7B/ITGA7/LUM/OASL/THBS1/CES1/HOXB2/HOXB3/MX2/MX1/USP18/LIF/LGALS2/SLITRK4 | 38 |
| CHYLA_CBFA2T3_TARGETS_UP | CHYLA_CBFA2T3_TARGETS_UP | CHYLA_CBFA2T3_TARGETS_UP | 61/1438 | 387/23056 | 0.1576227 | 2.527225 | 7.814418 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/GBP4/GFI1/C1orf54/S100A11/FCGR2A/IKBKE/CD34/HSD11B1/ITPKB/HNMT/FNDC3B/ANXA3/SGMS2/TMEM144/TSLP/PPIC/TGFBI/STING1/SERPINB1/GMPR/MDGA1/RBPMS/PLEKHA2/TEK/CEMIP2/PTGS1/NEK6/DNMBP/PTPRJ/CASP1/UBASH3B/TNFRSF1A/C1R/GPRC5A/EMP1/ARHGDIB/KRT80/KRT7/KRT18/DRAM1/SELPLG/FLT1/ALOX5AP/LCP1/PLEK2/UACA/TNFRSF12A/IL21R/CTF1/HOXB2/SERPINB2/ELANE/GADD45B/EBI3/GMFG/CEBPB/CYTH4/STARD8/ITM2A/ARHGEF6 | 61 |
| GOBP_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | 47/1438 | 256/23056 | 0.1835938 | 2.943628 | 8.065291 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/CDA/ZC3H12A/GFI1/PTPN22/NLRP3/IL1A/IL1B/IL36G/IRAK2/WNT5A/PLSCR4/SPON2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/TNIP3/CSF2/BMP6/TNFAIP3/SASH1/IL6/CD36/SERPINE1/ADAM9/CD274/PDCD1LG2/NOTCH1/ANKRD1/TRIM5/CASP1/CARD16/KLRC4-KLRK1/EDNRB/NFKBIA/CD68/CCL5/CSF3/ZFP36/AXL/TGFB1/SIRPA/DEFB124/CEBPB | 47 |
| KEGG_DILATED_CARDIOMYOPATHY | KEGG_DILATED_CARDIOMYOPATHY | KEGG_DILATED_CARDIOMYOPATHY | 26/1438 | 90/23056 | 0.2888889 | 4.631865 | 8.903537 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/TGFB2/ITGB6/ITGA6/ITGA4/DES/TNNC1/ITGB5/ITGA2/LAMA2/ITGB8/ADCY8/TPM2/ITGA8/CACNA2D4/ITGA5/ITGA7/IGF1/ACTC1/TPM1/ITGA11/ITGA3/SGCA/ITGB4/TGFB1/CACNG6 | 26 |
| LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_DN | 19/1438 | 48/23056 | 0.3958333 | 6.346546 | 9.563321 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/RUNX3/AGT/TGFA/TGFBR2/SPP1/EGF/DAB2/ITGA2/INHBA/SEMA3C/FZD1/ANGPT1/COL5A1/IGFBP6/THBS1/LHX1/APOE/GPC4 | 19 |
| REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES | REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES | REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES | 17/1438 | 38/23056 | 0.4473684 | 7.172828 | 9.821920 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/LTBP1/EFEMP1/BMP10/ITGB6/FN1/ITGB5/ITGB8/ITGA8/EFEMP2/BMP4/LTBP2/FBLN5/FBN1/EMILIN2/TGFB1/BMP2 | 17 |
| CAIRO_HEPATOBLASTOMA_CLASSES_DN | CAIRO_HEPATOBLASTOMA_CLASSES_DN | CAIRO_HEPATOBLASTOMA_CLASSES_DN | 42/1438 | 214/23056 | 0.1962617 | 3.146738 | 8.137165 | 0.0000000 | 0.0000000 | 0.0000000 | MTMR11/ECM1/FMO3/LMOD1/HSD11B1/IL1R1/AOX1/BHLHE40/RARB/UBA7/MYLK/AMOTL2/AADAC/BCL6/SLC4A4/FAT4/CTSO/TFAP2A/LAMA2/RARRES2/ITGA8/ZCCHC24/MMRN2/FAS/ACSL5/HTRA1/PAMR1/CASP4/C1S/C1R/TNS2/IGF1/HPD/NFKBIA/COPZ2/ABCA6/HSPB6/PLA2G4C/RRAS/COL18A1/IL2RB/ITM2A | 42 |
| GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | 33/1438 | 141/23056 | 0.2340426 | 3.752493 | 8.455321 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF18/EDN2/CSF1/TNFSF18/IL1R1/IL1A/ITGA4/WNT5A/CXCL8/VEGFC/ITGA2/F2RL1/EDN1/GPSM3/PLA2G7/IL6/SERPINE1/PTN/RARRES2/C3AR1/NCKAP1L/MMP14/BDKRB1/THBS1/CCL5/CCR7/TNFSF14/ICAM1/PLVAP/C5AR1/DEFB124/RAC2/XG | 33 |
| GOBP_CARDIAC_CHAMBER_MORPHOGENESIS | GOBP_CARDIAC_CHAMBER_MORPHOGENESIS | GOBP_CARDIAC_CHAMBER_MORPHOGENESIS | 31/1438 | 126/23056 | 0.2460317 | 3.944720 | 8.548336 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/CCN1/TGFB2/BMP10/NRP2/TGFBR2/TNNC1/WNT5A/HEG1/HES1/FGFRL1/SLIT2/FOXC1/DSP/CITED2/ADGRG6/SEMA3C/FZD1/ZFPM2/TEK/NOTCH1/NRP1/FGFR2/BMP4/TPM1/SMAD6/FOXF1/NOG/GATA6/TGFB1/BMP2 | 31 |
| GOBP_REGIONALIZATION | GOBP_REGIONALIZATION | GOBP_REGIONALIZATION | 57/1438 | 351/23056 | 0.1623932 | 2.603711 | 7.808601 | 0.0000000 | 0.0000000 | 0.0000000 | RNF220/PIFO/OSR1/CYP26B1/DLX1/DLX2/NRP2/BHLHE40/WNT5A/HES1/LEF1/IRX2/GDNF/FOXD1/FOXC1/EDN1/MDFI/TDRD6/TBX18/CITED2/HOXA2/HOXA3/HOXA7/GLI3/PKD1L1/SEMA3C/SEMA3A/SHH/EXT1/DMRT2/PCSK5/CRB2/NOTCH1/NRP1/DKK1/HHEX/FGFR2/WT1/ALX4/BHLHE41/GLI1/BMP4/SIX1/ALDH1A2/FOXB1/SMAD6/FOXF1/LHX1/MEOX1/HOXB2/HOXB3/HOXB7/NOG/C3/BMP2/GATA5/WNT7B | 57 |
| CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | 20/1438 | 54/23056 | 0.3703704 | 5.938289 | 9.370113 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/PTGS2/NID1/IL1R1/CCDC80/IGSF10/CXCL6/CXCL2/OSMR/DDR1/LAMA4/PDK4/FAS/FGFR2/LTBP2/FOS/LOXL1/C3/ZFP36/CEBPB | 20 |
| VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 | VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 | VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 | 20/1438 | 54/23056 | 0.3703704 | 5.938289 | 9.370113 | 0.0000000 | 0.0000000 | 0.0000000 | HSPG2/RHOC/NID1/COL3A1/FN1/COL6A3/ITGB5/SPARC/LAMA4/SERPINE1/ZYX/ADAM9/PLAT/TCF7L2/CD44/MMP3/MMP14/JUP/ITGA3/ICAM1 | 20 |
| BLANCO_MELO_COVID19_SARS_COV_2_POS_PATIENT_LUNG_TISSUE_UP | BLANCO_MELO_COVID19_SARS_COV_2_POS_PATIENT_LUNG_TISSUE_UP | BLANCO_MELO_COVID19_SARS_COV_2_POS_PATIENT_LUNG_TISSUE_UP | 37/1438 | 173/23056 | 0.2138728 | 3.429104 | 8.271171 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/IFI44L/GBP5/CD53/S100A11/RTP4/PLAC8/DDX60L/TRIM38/SAMD9/SAMD9L/CA1/TMEM71/APBB1IP/SRGN/ANKRD22/IFITM2/IFITM3/CARD16/C3AR1/METTL7B/ALOX5AP/LCP1/TNFSF13B/CYP19A1/BCL2A1/HS3ST3A1/KCNJ2/TNFSF14/ADGRE1/CACNA1A/CD37/FPR1/MX2/MX1/APOBEC3A/ARSL | 37 |
| GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP | 27/1438 | 98/23056 | 0.2755102 | 4.417360 | 8.743614 | 0.0000000 | 0.0000000 | 0.0000000 | S100A10/CD34/SEMA3B/CXCL6/NPNT/TGFBI/RNF144B/ID4/RCAN2/PTN/PDGFRL/CLU/SULF1/CTHRC1/HAS2/ADM/CARNS1/CRYAB/C1S/SLC38A4/POSTN/FOS/CRIP1/CCL5/COLEC12/PROCR/IL13RA1 | 27 |
| GOBP_GASTRULATION | GOBP_GASTRULATION | GOBP_GASTRULATION | 39/1438 | 190/23056 | 0.2052632 | 3.291062 | 8.178484 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/LAMB3/OSR1/ITGA4/COL5A2/FN1/TGFBR2/COL7A1/WNT5A/COL8A1/PHLDB2/ITGB5/LEF1/ITGA2/FOXC1/COL12A1/GJA1/INHBA/EXT1/KLF4/CRB2/COL5A1/ITGA8/DKK1/FGFR2/APOA1/ITGA5/ITGA7/HMGA2/MMP14/BMP4/MMP2/FOXF1/LHX1/ITGA3/NOG/ITGB4/GATA6/MBP | 39 |
| GOMF_CYTOKINE_BINDING | GOMF_CYTOKINE_BINDING | GOMF_CYTOKINE_BINDING | 33/1438 | 142/23056 | 0.2323944 | 3.726067 | 8.403970 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/TNFRSF1B/IL22RA1/GBP1/HJV/LTBP1/IL1R1/ITGA4/NRP2/ACKR3/TGFBR2/ACKR2/CCR3/OSMR/IL31RA/CD109/CD36/NRP1/LRRC32/FZD4/TNFRSF1A/THBS1/CCR7/NOG/TMC8/TNFRSF11A/ELANE/EBI3/IL27RA/IL12RB1/ZFP36/IL2RB/IL13RA1 | 33 |
| BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | 38/1438 | 182/23056 | 0.2087912 | 3.347629 | 8.200651 | 0.0000000 | 0.0000000 | 0.0000000 | HSPG2/EDN2/LGR6/PTPN14/CNIH3/ACTG2/FAP/EPHA3/COL8A1/FSTL1/MYLK/ITGB5/SEMA5A/NPR3/ADAMTS12/MDFI/LAMA2/PERP/AQP1/CAV1/PTPRZ1/FLNC/FBXO32/TPM2/ZCCHC24/AHNAK/TAGLN/MSRB3/NAV3/UACA/CAVIN1/COPZ2/CNN2/MYL9/RUNX1/MYH9/SRPX2/BGN | 38 |
| GOBP_REGULATION_OF_T_CELL_PROLIFERATION | GOBP_REGULATION_OF_T_CELL_PROLIFERATION | GOBP_REGULATION_OF_T_CELL_PROLIFERATION | 37/1438 | 174/23056 | 0.2126437 | 3.409397 | 8.227923 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/VCAM1/PTPN22/TNFSF18/PTPRC/IL1A/IL1B/TGFBR2/HES1/IL15/HLA-E/TNFRSF21/IL6/GPNMB/SHH/IDO1/CD274/PDCD1LG2/ANXA1/SFTPD/LRRC32/NCKAP1L/IGF1/TNFSF13B/BMP4/CCL5/EBI3/TNFSF9/CD70/IL27RA/IL12RB1/IL4I1/PRNP/SDC4/CEBPB/ICOSLG/RAC2 | 37 |
| HP_FRAGILE_SKIN | HP_FRAGILE_SKIN | HP_FRAGILE_SKIN | 16/1438 | 34/23056 | 0.4705882 | 7.545120 | 9.850081 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/LAMB3/ITGA6/COL3A1/COL5A2/COL7A1/ADAMTS2/DSP/HFE/COL5A1/MMP1/C1S/JUP/ITGA3/COL1A1/ITGB4 | 16 |
| DANG_REGULATED_BY_MYC_DN | DANG_REGULATED_BY_MYC_DN | DANG_REGULATED_BY_MYC_DN | 46/1438 | 251/23056 | 0.1832669 | 2.938388 | 7.963736 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/GBP2/VCAM1/TCHH/NIBAN1/COL3A1/FN1/COL6A3/TGFBR2/FSTL1/PLD1/IL1RAP/PLAC8/HBEGF/SPARC/SERPINB1/EDN1/IER3/CCN2/PERP/AQP1/INHBA/FZD1/SERPINE1/CAV1/GAS1/KLF4/COL5A1/FAS/ADM/CASP1/CRYAB/POSTN/ZFP36L1/FBLN5/THBS1/TPM1/CSPG4/IFI35/COL1A1/TGFB1/JPH2/HMOX1/PDGFB/MSN/PLS3 | 46 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | 40/1438 | 199/23056 | 0.2010050 | 3.222790 | 8.122124 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ZC3H12A/PTPN22/ILDR2/LAX1/SERPINE2/BCL6/BMP6/ADTRP/HFE/TNFRSF21/GPNMB/GLI3/PODXL/SHH/ZNF703/IDO1/CD274/PDCD1LG2/ANXA1/KLF4/NOTCH1/SFTPD/LRRC32/APOA1/UBASH3B/NCKAP1L/BMP4/IL4R/ADAMTS18/C1QTNF1/MBP/FXYD5/TGFB1/IL4I1/PRNP/BMP2/SDC4/CEBPB/RUNX1 | 40 |
| GOBP_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | GOBP_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | GOBP_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 32/1438 | 135/23056 | 0.2370370 | 3.800505 | 8.416677 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/CRIM1/TWIST2/PPARG/WWTR1/OSTN/NPNT/VEGFC/BMP6/RUNX2/TENT5A/FAM20C/IL6/HOXA2/GLI3/CEBPD/CTHRC1/CCN4/NOTCH1/FGFR2/YAP1/WNT10B/GLI1/IGF1/PRKD1/BMP4/SMAD6/NOG/SOX9/BMP2/CEBPB/WNT7B | 32 |
| GOBP_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | 23/1438 | 73/23056 | 0.3150685 | 5.051613 | 8.942115 | 0.0000000 | 0.0000000 | 0.0000000 | HES1/EREG/NPNT/PRDM6/TBX18/SOD2/SHH/NOTCH1/ITGA8/FGFR2/ADM/EFEMP2/EDNRB/NFATC4/BMP4/SIX1/RBPMS2/FOXF1/MYOCD/SOX9/GATA6/NFATC2/PDGFB | 23 |
| CERVERA_SDHB_TARGETS_1_UP | CERVERA_SDHB_TARGETS_1_UP | CERVERA_SDHB_TARGETS_1_UP | 30/1438 | 121/23056 | 0.2479339 | 3.975218 | 8.462845 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/LONRF2/SCTR/LYPD1/LYPD6B/ITGB6/SERPINE2/ACKR3/TMEM40/SUSD5/FSTL1/SUCNR1/TMEM156/CDC20B/EDN1/AQP1/INHBA/LOXL2/ANXA13/PCSK5/MYOF/HTRA1/PRSS23/UBASH3B/KRT80/TNFRSF19/RAB20/KRT17/COL1A1/CLIC6 | 30 |
| GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 41/1438 | 209/23056 | 0.1961722 | 3.145304 | 8.035292 | 0.0000000 | 0.0000000 | 0.0000000 | ECM1/OSR1/TGFA/ITGA4/NRP2/CCR3/WNT5A/CLDN1/KDR/EPGN/EGF/VEGFC/SEMA5A/RREB1/BMP6/TNFAIP3/CCL26/CAV2/PTN/SHH/ZNF703/HAS2/TEK/B4GALT1/NOTCH1/JCAD/NRP1/TCF7L2/FGFR2/HTRA1/YAP1/IGF1/PRKD1/BMP4/CDH13/NOG/SOX9/C5AR1/BMP2/HMOX1/PDGFB | 41 |
| MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | MEISSNER_BRAIN_HCP_WITH_H3K27ME3 | 48/1438 | 271/23056 | 0.1771218 | 2.839861 | 7.857770 | 0.0000000 | 0.0000000 | 0.0000000 | FOXD2/GFI1/LGR6/CDCP1/NKX3-2/IRX4/IRX2/PRDM6/TDRD6/SIM1/FGF20/DMRTA1/TPM2/COL13A1/CYP26A1/HMX3/WT1/ALX4/PLEKHG6/WNT10B/KRT7/KRT18/HMGA2/SIX1/LTBP2/TNFAIP2/FOXB1/LOXL1/BNC1/ALDH1A3/MMP2/CLDN7/SLC47A1/LHX1/KRT19/HOXB7/DLX4/DLX3/B3GNT3/BCL3/NPAS1/REM1/CYP24A1/TFAP2C/GATA5/SIM2/WNT7B/CELSR1 | 48 |
| BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN | BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN | BERENJENO_TRANSFORMED_BY_RHOA_FOREVER_DN | 15/1438 | 30/23056 | 0.5000000 | 8.016690 | 9.918315 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/PTGS2/CAVIN2/CCDC80/CXCL2/EREG/ANXA3/NPNT/HBEGF/IER3/GJA1/ANKRD1/PHLDA1/POSTN/BNC1 | 15 |
| GOBP_ENDOTHELIAL_CELL_PROLIFERATION | GOBP_ENDOTHELIAL_CELL_PROLIFERATION | GOBP_ENDOTHELIAL_CELL_PROLIFERATION | 40/1438 | 201/23056 | 0.1990050 | 3.190722 | 8.045425 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/ECM1/CD34/ITGA4/NRP2/PPARG/CCR3/WNT5A/KDR/EGF/VEGFC/SEMA5A/SPARC/FGF18/BMP6/BMPER/CCL26/CAV2/CAV1/LOXL2/SULF1/ANGPT1/TEK/JCAD/NRP1/ALOX5/MMRN2/APOA1/FLT1/MMP14/PRKD1/BMP4/THBS1/ALDH1A2/CDH13/APOE/BMP2/HMOX1/PDGFB | 40 |
| GOBP_RESPONSE_TO_MECHANICAL_STIMULUS | GOBP_RESPONSE_TO_MECHANICAL_STIMULUS | GOBP_RESPONSE_TO_MECHANICAL_STIMULUS | 40/1438 | 201/23056 | 0.1990050 | 3.190722 | 8.045425 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/AGT/IL1B/CASP8/SERPINE2/TGFBR2/TLR3/ITGA2/BMP6/EDN1/CITED2/AQP1/PKD1L1/PTN/TNFRSF10A/TRPA1/TMC1/GSN/FAS/ANKRD1/BAG3/FOSL1/CASP1/KCNA5/TNFRSF1A/MMP14/NFKBIA/FOS/BDKRB1/THBS1/MMP2/PIEZO1/JUP/COL1A1/KCNJ2/SOX9/PIEZO2/CNN2/TNFSF14/MAG | 40 |
| GOBP_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 52/1438 | 309/23056 | 0.1682848 | 2.698174 | 7.750926 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/ZC3H12A/VCAM1/IFI16/PTGS2/PTPRC/NUAK2/AGT/MAP1LC3C/IL1B/ITGA4/CASP8/UCN2/IL15/TLR3/ITGA2/BMP6/AQP1/PDK4/TNFRSF10A/GSDMD/AQP3/AKR1C3/FAS/ANKRD1/BAG3/FOSL1/CASP1/TNFRSF1A/NUAK1/POSTN/FOXO1/DNAJC15/PRKD1/FOS/PIEZO1/CD68/MYH13/MYOCD/COL1A1/WIPI1/KCNJ2/SOX9/PIEZO2/CNN2/TNFSF14/MAG/AXL/CYP24A1/MN1/GAS2L1/HMOX1 | 52 |
| BAELDE_DIABETIC_NEPHROPATHY_DN | BAELDE_DIABETIC_NEPHROPATHY_DN | BAELDE_DIABETIC_NEPHROPATHY_DN | 65/1438 | 437/23056 | 0.1487414 | 2.384828 | 7.537963 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/CCN1/PTPN7/PTPN14/CRIM1/NMI/COL3A1/SP100/SEMA3B/MYLK/ITGB5/MME/CXCL2/CDS1/SEMA5A/RAI14/OSMR/IQGAP2/FOXC1/PSMB9/TAPBP/CLIC5/GJA1/CCN2/CITED2/PDGFA/GPNMB/SEMA3C/SERPINE1/PODXL/RARRES2/CEBPD/SULF1/AQP3/ANXA1/GAS1/FGFR2/HTRA1/ADM/WT1/ALDH3B1/BIRC3/CASP1/C1S/C1R/YBX3/GPRC5A/POSTN/MYO1E/LOXL1/NUPR1/IFI35/ITGA3/AXL/BCAM/NECTIN2/KLK6/BMP2/MYL9/SDC4/APOL1/MYH9/COL4A6/PLS3/ZNF185 | 65 |
| PID_AVB3_INTEGRIN_PATHWAY | PID_AVB3_INTEGRIN_PATHWAY | PID_AVB3_INTEGRIN_PATHWAY | 23/1438 | 74/23056 | 0.3108108 | 4.983348 | 8.851654 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/COL3A1/COL5A2/CASP8/FN1/COL6A3/TGFBR2/COL7A1/COL8A1/KDR/SPP1/EDIL3/COL12A1/COL14A1/COL5A1/COL13A1/VCL/MFGE8/COL1A1/COL9A3/COL6A2/COL4A6/COL4A5 | 23 |
| GOBP_RENAL_TUBULE_DEVELOPMENT | GOBP_RENAL_TUBULE_DEVELOPMENT | GOBP_RENAL_TUBULE_DEVELOPMENT | 26/1438 | 94/23056 | 0.2765957 | 4.434765 | 8.606177 | 0.0000000 | 0.0000000 | 0.0000000 | AGT/OSR1/WWTR1/HES1/NPNT/IRX2/ADAMTS16/GDNF/FOXD1/GLI3/SHH/NOTCH1/WT1/YAP1/BMP4/SIX1/SIX4/SOX8/SALL1/LHX1/HOXB7/NOG/SOX9/BMP2/LIF/WNT7B | 26 |
| FOROUTAN_TGFB_EMT_DN | FOROUTAN_TGFB_EMT_DN | FOROUTAN_TGFB_EMT_DN | 28/1438 | 108/23056 | 0.2592593 | 4.156802 | 8.480883 | 0.0000000 | 0.0000000 | 0.0000000 | CFH/ELF3/CAVIN2/MITF/RBM47/EREG/SERPINB1/TFAP2A/TPD52L1/CITED2/PDK4/CEBPD/AQP3/EHF/PLAAT4/PLAAT3/RAB38/BIRC3/MPZL2/SCNN1A/EMP1/TNFAIP2/ALDH1A3/KRT15/KRT19/GPRC5C/MBP/GDF15 | 28 |
| GOBP_COLLAGEN_FIBRIL_ORGANIZATION | GOBP_COLLAGEN_FIBRIL_ORGANIZATION | GOBP_COLLAGEN_FIBRIL_ORGANIZATION | 21/1438 | 62/23056 | 0.3387097 | 5.430661 | 9.009721 | 0.0000000 | 0.0000000 | 0.0000000 | OPTC/TGFB2/COL3A1/COL5A2/ADAMTS3/ADAMTS12/ADAMTS2/FOXC1/COL12A1/LOXL2/EXT1/COL14A1/COL5A1/COL13A1/TLL2/LOXL4/EFEMP2/SERPINH1/LUM/LOXL1/COL1A1 | 21 |
| GOBP_MUSCLE_CONTRACTION | GOBP_MUSCLE_CONTRACTION | GOBP_MUSCLE_CONTRACTION | 56/1438 | 349/23056 | 0.1604585 | 2.572691 | 7.635378 | 0.0000000 | 0.0000000 | 0.0000000 | HTR1D/TRIM63/ZC3H12A/EDN2/CASQ1/PTGS2/LMOD1/ATP2B4/AGT/BMP10/DES/KCNE4/TNNC1/MYLK/NPNT/GDNF/ITGA2/ADRB2/DSP/EDN1/GJA1/TRDN/CCN2/UTRN/CAV1/LMOD2/STC1/ASPH/SULF1/TPM2/GSN/HTR7/MYOF/ARHGAP42/CRYAB/KCNA5/SPX/EDNRB/TPM1/HCN4/MYH13/MYH8/MYH4/MYH1/MYH2/MYOCD/JUP/MYL4/SGCA/KCNJ2/MYOM1/DSG2/CNN1/SCN1B/MYL9/SMPX | 56 |
| PEREZ_TP63_TARGETS | PEREZ_TP63_TARGETS | PEREZ_TP63_TARGETS | 57/1438 | 359/23056 | 0.1587744 | 2.545690 | 7.612715 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/RUNX3/NIBAN1/RASSF5/TMEM63A/LBH/DLX2/EPHA4/SLIT2/SMIM32/FGF18/GFPT2/ID4/MOXD1/SASH1/SYNJ2/MICALL2/C7orf57/FZD1/GPR37/TNFRSF10C/CLU/ST3GAL1/EPPK1/AQP3/PCSK5/COL27A1/CLIC3/ZCCHC24/PTPRJ/ELMOD1/CRYAB/NUAK1/ZIC2/CGNL1/SMAD6/SOX8/CLDN6/MAF/CDYL2/CRISPLD2/FOXF1/ADAP2/COL1A1/SOCS3/METRNL/GATA6/PLIN4/BMP2/COL9A3/MX1/COL18A1/LGALS2/WNT7B/MXRA5/ARHGEF6/GABRE | 57 |
| CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | 30/1438 | 123/23056 | 0.2439024 | 3.910580 | 8.347491 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/VCAM1/CSF1/IFI16/NID1/IL1R1/AOX1/PHLDB2/IGSF10/CXCL6/NPNT/OSMR/ADAM19/LAMA4/THBS2/IL6/PDK4/CEBPD/HAS2/APBB1IP/FGFR2/CASP4/HMGA2/PHLDA1/LTBP2/THBS1/LOXL1/C3/CEBPB/GPC4 | 30 |
| GOBP_MUSCLE_ORGAN_MORPHOGENESIS | GOBP_MUSCLE_ORGAN_MORPHOGENESIS | GOBP_MUSCLE_ORGAN_MORPHOGENESIS | 24/1438 | 81/23056 | 0.2962963 | 4.750631 | 8.721142 | 0.0000000 | 0.0000000 | 0.0000000 | S1PR1/TGFB2/BMP10/XIRP2/COL3A1/TNNC1/WNT5A/MYLK/HEG1/FOXC1/DSP/FZD1/ZFPM2/NOTCH1/ANKRD1/FGFR2/EFEMP2/BMP4/ACTC1/TPM1/NOG/TGFB1/BMP2/LIF | 24 |
| GOBP_FAT_CELL_DIFFERENTIATION | GOBP_FAT_CELL_DIFFERENTIATION | GOBP_FAT_CELL_DIFFERENTIATION | 44/1438 | 238/23056 | 0.1848739 | 2.964154 | 7.855603 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/RNASEL/PTGS2/LAMB3/PPARG/WNT5A/WWTR1/HES1/SULT1E1/PLAC8/CDS1/ADRB2/RREB1/ID4/PSMB8/ADGRF5/SOD2/IL6/RARRES2/EBF2/CEBPD/FABP4/GDF6/ZFPM2/CCN4/KLF4/ALOX5/TCF7L2/YAP1/WNT10B/HMGA2/FOXO1/SIX1/ZFP36L1/DIO2/SMAD6/SOX8/METRNL/ZFP36/TGFB1/IL11/BMP2/CEBPB/PNPLA3 | 44 |
| ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | 62/1438 | 409/23056 | 0.1515892 | 2.430488 | 7.528262 | 0.0000000 | 0.0000000 | 0.0000000 | SPSB1/HSPB7/ZC3H12A/RPE65/NEXN/PTGS2/ELF3/CAMK1G/IL1R1/IL1B/IRAK2/WNT5A/TM4SF18/RTP4/CLDN1/TEC/SULT1E1/CXCL1/CXCL3/CXCL2/EREG/LEF1/TSLP/EDN1/RNF144B/IER3/FILIP1/ITGB8/IL6/FZD1/SERPINE1/FOXP2/CA13/DMRTA1/DDX58/B4GALT1/KLF4/NFKB2/ADM/CD44/FOSL1/FZD4/VWF/DRAM1/OASL/NPAS3/TNFAIP2/AHNAK2/SLC28A1/CTRB1/CDH15/SLFN5/CSF3/SERPINB2/TNFSF9/ICAM1/RELB/SDC4/ADAMTS5/MX2/USP18/MXRA5 | 62 |
| GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 56/1438 | 350/23056 | 0.1600000 | 2.565341 | 7.610739 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/GBP5/PTPN22/IFI16/MR1/CFH/IKBKE/IL1B/NMI/CASP8/PPARG/WNT5A/CD96/PARP14/TXK/CXCL6/EREG/IL15/DDX60/F2RL1/STING1/BMP6/TRIM38/HLA-E/MICA/MICB/TNFAIP3/SASH1/RAET1E/AHR/CD36/TRIM56/CD274/DDX58/MBL2/HTRA1/TSPAN32/TRIM5/BIRC3/CARD16/KLRD1/KLRC4-KLRK1/OASL/NLRC5/RNF135/CCL5/DHX58/IFI35/EMILIN2/GATA6/IL12RB1/NECTIN2/APOE/IL4I1/USP18/APOBEC3G | 56 |
| GOBP_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | GOBP_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | GOBP_INTEGRIN_MEDIATED_SIGNALING_PATHWAY | 28/1438 | 109/23056 | 0.2568807 | 4.118666 | 8.417313 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/ITGB6/ITGA6/ITGA4/COL3A1/FN1/ITGB5/TXK/TEC/DAB2/ITGA2/CCN2/ITGB8/PTN/ZYX/ADAM9/ITGA8/NRP1/TSPAN32/APOA1/ITGA5/ITGA7/PRKD1/ITGA11/LAT/ITGA3/ITGB4/MYH9 | 28 |
| GOBP_RESPONSE_TO_RETINOIC_ACID | GOBP_RESPONSE_TO_RETINOIC_ACID | GOBP_RESPONSE_TO_RETINOIC_ACID | 28/1438 | 109/23056 | 0.2568807 | 4.118666 | 8.417313 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/BRINP3/WNT9A/OSR1/CYP26B1/WNT5A/EPHA3/BMP6/MICB/PDGFA/HOXA2/AQP1/STRA8/AQP3/KLF4/DKK1/CYP26A1/FGFR2/FZD4/YAP1/WNT10B/LTK/ALDH1A2/MMP2/COL1A1/SOX9/GATA6/WNT7B | 28 |
| DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | 37/1438 | 179/23056 | 0.2067039 | 3.314162 | 8.016320 | 0.0000000 | 0.0000000 | 0.0000000 | OLFML3/C1orf54/CRABP2/NIBAN1/CYP26B1/COL5A2/SEMA3B/FNDC3B/FAT4/INPP4B/PLK2/SNCAIP/TPBG/LAMA2/EPHB4/TRIP6/PTN/PDGFRL/PLAG1/TRPS1/EXT1/CREB3L1/EFEMP2/SERPINH1/FZD4/TNFRSF1A/HMGA2/CPM/NAV3/NUAK1/BMP4/RHBDF1/MMP2/COLEC12/EMP3/ITM2A/GPC4 | 37 |
| GOBP_EMBRYONIC_ORGAN_MORPHOGENESIS | GOBP_EMBRYONIC_ORGAN_MORPHOGENESIS | GOBP_EMBRYONIC_ORGAN_MORPHOGENESIS | 50/1438 | 294/23056 | 0.1700680 | 2.726765 | 7.685215 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TBX15/PRRX1/OSR1/EFEMP1/DLX2/RARB/TGFBR2/WNT5A/FOXL2/HES1/NKX3-2/TFAP2A/EDN1/MDFI/RUNX2/TBX18/GJA1/CITED2/HOXA1/HOXA2/HOXA3/HOXA7/GLI3/SHH/FZD6/CTHRC1/CRB2/NOTCH1/ITGA8/FGFR2/HMX3/MICAL2/ALX4/YAP1/GLI1/MMP14/BMP4/SIX1/SIX4/FBN1/RBPMS2/ALDH1A3/FOXF1/LHX1/HOXB2/HOXB3/HOXB7/NOG/SOX9 | 50 |
| HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP | 21/1438 | 63/23056 | 0.3333333 | 5.344460 | 8.905586 | 0.0000000 | 0.0000000 | 0.0000000 | FUCA1/PTGS2/NLRP3/IL1B/KYNU/CXCL8/CXCL1/CXCL3/CXCL2/EREG/HBEGF/IER3/VNN1/SOD2/KLF4/ADM/MS4A4A/GLIPR1/RAB20/WIPI1/ZNF185 | 21 |
| GOBP_REGENERATION | GOBP_REGENERATION | GOBP_REGENERATION | 38/1438 | 188/23056 | 0.2021277 | 3.240789 | 7.956465 | 0.0000000 | 0.0000000 | 0.0000000 | PRRX1/LGR6/EPHA4/TGFBR2/LAMB2/CLDN1/TXK/TEC/ANXA3/SPP1/GJA1/IL6/GLI3/PTN/EPPK1/SPAAR/ANXA1/KLF4/PTPN3/NOTCH1/MYOZ1/ADM/YAP1/NNMT/WNT10B/GLI1/IGF1/FLT3/LCP1/SERPINA10/MMP2/SGCA/MAG/AXL/KLK6/CEBPB/RUNX1/HMOX1 | 38 |
| PID_SYNDECAN_1_PATHWAY | PID_SYNDECAN_1_PATHWAY | PID_SYNDECAN_1_PATHWAY | 18/1438 | 46/23056 | 0.3913043 | 6.273931 | 9.234414 | 0.0000000 | 0.0000000 | 0.0000000 | COL3A1/COL5A2/COL6A3/COL7A1/COL8A1/COL12A1/MET/COL14A1/COL5A1/COL13A1/MMP1/CCL5/COL1A1/TGFB1/COL9A3/COL6A2/COL4A6/COL4A5 | 18 |
| YANG_BCL3_TARGETS_UP | YANG_BCL3_TARGETS_UP | YANG_BCL3_TARGETS_UP | 54/1438 | 333/23056 | 0.1621622 | 2.600007 | 7.585174 | 0.0000000 | 0.0000000 | 0.0000000 | PERM1/GBP2/GBP4/TMEM37/NMI/SP110/TGFBR2/UBA7/EPHA3/PARP14/IGSF10/MME/RTP4/RBM47/TGFBI/SERPINB1/EDN1/PSMB8/PSMB9/TNFRSF21/RSPO3/IL6/SEMA3D/PDK4/SERPINE1/PTN/PLAT/DDX58/AQP7/PCSK5/ITGA8/ANXA8L1/TRIM5/MMP10/MMP3/C1R/KRT7/IGFBP6/OASL/EDNRB/NID2/CD68/DHX58/IFI35/ABCA8/SERPINB2/TNFSF9/PEX11G/SDCBP2/ADRA1D/THBD/MYL9/BACE2/MX1 | 54 |
| BAELDE_DIABETIC_NEPHROPATHY_UP | BAELDE_DIABETIC_NEPHROPATHY_UP | BAELDE_DIABETIC_NEPHROPATHY_UP | 25/1438 | 89/23056 | 0.2808989 | 4.503758 | 8.541443 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/CD34/SLCO2A1/UGT2B7/CRHBP/SLC6A7/CCDC69/ATP10B/ADGRF5/AQP1/CLU/RBPMS/TEK/AKR1C3/ZCCHC24/BBOX1/CRIP1/LTK/MT2A/PECAM1/PTGIS/GGT1/GAS2L1/STARD8/ITM2A | 25 |
| SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | 53/1438 | 324/23056 | 0.1635802 | 2.622744 | 7.586789 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/PDZK1IP1/GBP1/S100A2/IFI16/PTGS2/PLA2G4A/PRELP/LTBP1/CYP26B1/ACTG2/KYNU/ITGA6/TMEM158/TM4SF1/WWTR1/CLDN1/CXCL8/CXCL5/TDO2/HAPLN1/FOXC1/EDN1/ID4/CYP39A1/TNFRSF21/PERP/SOD2/PTPRZ1/TNFRSF11B/OBP2B/DKK1/BBOX1/CD44/CRYAB/YBX3/MMP14/MFGE8/MSLN/IL32/KRT17/SOX9/SLC16A3/SERPINB2/MUC16/CD22/KCNN4/KLK6/TFAP2C/COL9A3/RAC2/LGALS2/BGN | 53 |
| BASSO_CD40_SIGNALING_UP | BASSO_CD40_SIGNALING_UP | BASSO_CD40_SIGNALING_UP | 27/1438 | 103/23056 | 0.2621359 | 4.202925 | 8.402333 | 0.0000000 | 0.0000000 | 0.0000000 | CAPG/IL1B/ELL2/IER3/TNFAIP3/TRAF1/MAP3K8/SRGN/NFKB2/PTPRE/CD44/LRRC32/KRT7/NCKAP1L/IRF9/NFKBIA/ZFP36L1/TNFAIP2/BCL2A1/CCR7/GADD45B/TNFSF9/ICAM1/KCNN4/ICOSLG/RAC2/LGALS1 | 27 |
| WIELAND_UP_BY_HBV_INFECTION | WIELAND_UP_BY_HBV_INFECTION | WIELAND_UP_BY_HBV_INFECTION | 27/1438 | 103/23056 | 0.2621359 | 4.202925 | 8.402333 | 0.0000000 | 0.0000000 | 0.0000000 | GBP1/GBP2/CD53/C1orf54/S100A10/IFI16/SP110/PLAC8/HLA-E/PSMB9/TAPBP/SOD2/GPNMB/PARP12/SRGN/PLAAT4/C3AR1/ARHGDIB/DRAM1/RAB20/SLC7A7/PSMB10/COTL1/CCL5/ADGRE1/APOL3/RAC2 | 27 |
| GOBP_NEGATIVE_REGULATION_OF_WOUND_HEALING | GOBP_NEGATIVE_REGULATION_OF_WOUND_HEALING | GOBP_NEGATIVE_REGULATION_OF_WOUND_HEALING | 23/1438 | 76/23056 | 0.3026316 | 4.852207 | 8.675523 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/FAP/TFPI/SERPINE2/PHLDB2/ADTRP/EDN1/CD109/PDGFA/SERPINE1/PLAT/EPPK1/ALOX5/MYOZ1/PLAU/UBASH3B/THBS1/ADAMTS18/C1QTNF1/SERPINB2/APOE/THBD/PDGFB | 23 |
| GOBP_NEGATIVE_REGULATION_OF_COAGULATION | GOBP_NEGATIVE_REGULATION_OF_COAGULATION | GOBP_NEGATIVE_REGULATION_OF_COAGULATION | 19/1438 | 52/23056 | 0.3653846 | 5.858350 | 9.045718 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/FAP/TFPI/SERPINE2/ADTRP/EDN1/PDGFA/SERPINE1/PLAT/PLAU/UBASH3B/THBS1/ADAMTS18/C1QTNF1/SERPINB2/APOE/THBD/PROCR/PDGFB | 19 |
| GOBP_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS | 22/1438 | 70/23056 | 0.3142857 | 5.039062 | 8.728751 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/AGT/IL1B/CASP8/TLR3/ITGA2/BMP6/AQP1/TNFRSF10A/FAS/ANKRD1/BAG3/CASP1/TNFRSF1A/PIEZO1/COL1A1/KCNJ2/SOX9/PIEZO2/CNN2/TNFSF14/MAG | 22 |
| GOBP_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_SMOOTH_MUSCLE_CELL_PROLIFERATION | 36/1438 | 173/23056 | 0.2080925 | 3.336426 | 7.955598 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/S1PR1/PTGS2/AGT/PPARG/TGFBR2/EREG/IL15/NPR3/ITGA2/HBEGF/EDN1/GJA1/TNFAIP3/SOD2/IL6/CCN4/TCF7L2/FGFR2/EFEMP2/IGF1/BMP4/THBS1/TPM1/RBPMS2/MMP2/CDH13/MYOCD/CCL5/ELANE/CNN1/TGFB1/APOE/BMP2/HMOX1/PDGFB | 36 |
| NAGASHIMA_NRG1_SIGNALING_UP | NAGASHIMA_NRG1_SIGNALING_UP | NAGASHIMA_NRG1_SIGNALING_UP | 36/1438 | 173/23056 | 0.2080925 | 3.336426 | 7.955598 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/CCN1/LAMC2/TGFB2/DLX2/BHLHE40/SEMA3B/HES1/LRRC15/F2RL1/HBEGF/EDN1/IER3/TNFRSF21/CCN2/ZYX/TNFRSF11B/EPPK1/AQP3/MAP3K8/VCL/PHLDA2/ADM/FOSL1/FOS/TNFRSF12A/GATA6/SERPINB8/GADD45B/KLF2/GDF15/ZFP36/LYPD3/CEBPB/CYP24A1/LIF | 36 |
| MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | 55/1438 | 345/23056 | 0.1594203 | 2.556046 | 7.510487 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/GFI1/EVA1A/NPAS2/VIPR1/SLIT2/SOWAHB/NPR3/BMP6/SIM1/HECW1/GPR37/MSC/COL14A1/DMRT2/PAPPA/FIBCD1/COL13A1/HTR7/CYP26A1/TCERG1L/NLRP6/PHLDA2/CCKBR/SYT12/PGR/SLC38A4/AMIGO2/FLT3/LRFN5/BMP4/LTBP2/ALDH1A2/BNC1/PITPNM3/CLDN7/HOXB2/HOXB3/HOXB7/DLX3/LLGL2/COLEC12/LIPG/TNFRSF11A/S1PR5/KCNK6/NPAS1/KCNA7/IL11/NFATC2/TFAP2C/GATA5/SIM2/PDGFB/CELSR1 | 55 |
| GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 20/1438 | 58/23056 | 0.3448276 | 5.528752 | 8.906390 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/OSR1/LAMB2/WWTR1/HES1/GDNF/GLI3/PODXL/SHH/EXT1/NOTCH1/WT1/YAP1/EDNRB/BMP4/MYO1E/SALL1/LHX1/LIF/PDGFB | 20 |
| GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 68/1438 | 476/23056 | 0.1428571 | 2.290483 | 7.337498 | 0.0000000 | 0.0000000 | 0.0000000 | MCOLN2/GBP5/PTPN22/S100A13/IFI16/PTGS2/PTPRC/RAB7B/CD34/AGT/NLRP3/IL1R1/IL1A/IL1B/CASP8/WNT5A/HEG1/IL1RAP/SPON2/TXK/EREG/IL15/TLR3/F2RL1/TSLP/CSF2/STING1/HLA-E/GPSM3/IL6/CD36/TRIM56/SERPINE1/CLU/IDO1/SULF1/GSDMD/CD274/DDX58/ANXA1/PAEP/SAA1/PTPRJ/CASP1/C3AR1/KLRC4-KLRK1/LUM/NFATC4/THBS1/IL4R/RNF135/CCR7/DHX58/GATA6/SERPINB7/MBP/ELANE/EBI3/C3/IL27RA/IL12RB1/TGFB1/BCL3/C5AR1/DEFB124/CEBPB/RUNX1/HMOX1 | 68 |
| GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE | 49/1438 | 288/23056 | 0.1701389 | 2.727901 | 7.610392 | 0.0000000 | 0.0000000 | 0.0000000 | GBP5/IFI16/PTGS2/IKBKE/AGT/NPAS2/IL1B/NMI/WNT5A/SUCNR1/TXK/EREG/IL15/TLR3/OSMR/ITGA2/F2RL1/TSLP/STING1/HLA-E/GPSM3/PLA2G7/RAET1E/IL6/TRIM56/SERPINE1/IDO1/FABP4/CCN4/MBL2/TRIM5/CASP1/TNFRSF1A/KLRD1/KLRC4-KLRK1/ALOX5AP/NFKBIA/NUPR1/NLRC5/CCL5/CCR7/IFI35/EMILIN2/TNFRSF11A/CREB3L3/C3/NECTIN2/CEBPB/LGALS1 | 49 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN | 40/1438 | 207/23056 | 0.1932367 | 3.098238 | 7.820968 | 0.0000000 | 0.0000000 | 0.0000000 | NIBAN1/HSD11B1/GXYLT2/BCL6/CXCL1/CXCL5/CXCL3/TDO2/GASK1B/IL7R/C9/DAB2/TGFBI/ADAM19/PLA2G7/ARHGAP18/GPNMB/PDK4/CLU/ADAM9/PCSK5/NRP1/ALOX5/PYROXD2/HTRA1/SLCO2B1/MMP1/EMP1/TMCC3/SLC7A7/MMP14/PYGL/SERPINA1/MAF/COLEC12/KLF2/C5AR1/FPR1/PRNP/ITM2A | 40 |
| REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING | REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING | REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING | 28/1438 | 111/23056 | 0.2522523 | 4.044456 | 8.292423 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/VCAM1/S1PR1/PTGS2/IL1A/IL1B/FN1/BCL6/CXCL8/IL6/CD36/CEBPD/ANXA1/ALOX5/SAA1/MMP1/MMP3/STAT6/FOXO1/FOS/IL4R/MMP2/SOCS3/ICAM1/TGFB1/LIF/HMOX1/IL13RA1 | 28 |
| BROWNE_HCMV_INFECTION_18HR_DN | BROWNE_HCMV_INFECTION_18HR_DN | BROWNE_HCMV_INFECTION_18HR_DN | 37/1438 | 182/23056 | 0.2032967 | 3.259533 | 7.892919 | 0.0000000 | 0.0000000 | 0.0000000 | VAMP5/COL3A1/MYLK/UGT2B7/CTSO/SEMA5A/CRHBP/GLI3/EPHB6/SHH/PNOC/RBPMS/MSC/ANGPT1/EXT1/TNFRSF11B/SLC22A18/CD44/PAMR1/ALDH3B1/LRRC32/TNS2/THBS1/ANXA2/CA12/LOXL1/ACSM3/PSMB10/CAVIN1/ABCA8/CACNA1A/AXL/RRAS/RIN2/PTGIS/COL6A2/RAC2 | 37 |
| GOBP_REGULATION_OF_WNT_SIGNALING_PATHWAY | GOBP_REGULATION_OF_WNT_SIGNALING_PATHWAY | GOBP_REGULATION_OF_WNT_SIGNALING_PATHWAY | 54/1438 | 337/23056 | 0.1602374 | 2.569147 | 7.484076 | 0.0000000 | 0.0000000 | 0.0000000 | RNF220/TRABD2B/LGR6/TRABD2A/WNT5A/WWTR1/LEF1/EGF/NKD2/SEMA5A/DAB2/SOX30/MDFI/TPBG/TBX18/RSPO3/TNFAIP3/GLI3/HECW1/FZD1/MDFIC/CAV1/SHH/ZNF703/SULF1/FZD6/CTHRC1/RSPO2/CCN4/NOTCH1/DKK1/HHEX/TCF7L2/FGFR2/FZD4/YAP1/WNT10B/IGFBP6/GLI1/LATS2/FOXO1/NFATC4/DACT1/SALL1/JUP/ITGA3/COL1A1/NOG/SOX9/ALPK2/TGFB1/APOE/BMP2/APCDD1L | 54 |
| GOBP_APPENDAGE_MORPHOGENESIS | GOBP_APPENDAGE_MORPHOGENESIS | GOBP_APPENDAGE_MORPHOGENESIS | 32/1438 | 142/23056 | 0.2253521 | 3.613156 | 8.055886 | 0.0000000 | 0.0000000 | 0.0000000 | ECE1/CRABP2/PRRX1/TGFB2/OSR1/CYP26B1/SP9/COL3A1/RARB/WNT5A/LEF1/TFAP2A/RUNX2/GJA1/GLI3/SEMA3C/SHH/ASPH/FZD6/RSPO2/EXT1/PCSK5/NOTCH1/DKK1/FGFR2/ALX4/FREM2/BMP4/ALDH1A2/SALL1/NOG/SOX9 | 32 |
| GOBP_DIGESTIVE_SYSTEM_DEVELOPMENT | GOBP_DIGESTIVE_SYSTEM_DEVELOPMENT | GOBP_DIGESTIVE_SYSTEM_DEVELOPMENT | 32/1438 | 142/23056 | 0.2253521 | 3.613156 | 8.055886 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/COL3A1/CPS1/RARB/TGFBR2/WNT5A/HES1/NKX3-2/CXCL8/PDGFC/GLI3/RARRES2/SHH/EXT1/PCSK5/NOTCH1/FGFR2/CCKBR/ALX4/YAP1/GLI1/EDNRB/BMP4/DACT1/ALDH1A2/RBPMS2/SALL1/FOXF1/MYOCD/GIP/GATA6/GATA5 | 32 |
| GOBP_STEM_CELL_DIFFERENTIATION | GOBP_STEM_CELL_DIFFERENTIATION | GOBP_STEM_CELL_DIFFERENTIATION | 41/1438 | 217/23056 | 0.1889401 | 3.029348 | 7.746440 | 0.0000000 | 0.0000000 | 0.0000000 | PTPRC/TGFB2/OSR1/LBH/NRP2/FN1/SEMA3B/HES1/SEMA5A/GDNF/FOXC1/EDN1/RBM24/RUNX2/CITED2/HOXA7/SEMA3C/SEMA3A/SEMA3D/FZD1/PTN/SHH/EXT1/NOTCH1/NRP1/FGFR2/YAP1/HMGA2/EDNRB/BMP4/SIX1/ESRRB/ALDH1A2/SOX8/MYOCD/MEOX1/SOX9/GATA6/SEMA6B/DNMT3L/LIF | 41 |
| GOBP_REGULATION_OF_COAGULATION | GOBP_REGULATION_OF_COAGULATION | GOBP_REGULATION_OF_COAGULATION | 22/1438 | 71/23056 | 0.3098592 | 4.968089 | 8.636596 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/FAP/TFPI/SERPINE2/F2RL1/ADTRP/EDN1/PDGFA/CD36/SERPINE1/CAV1/PLAT/PLAU/UBASH3B/THBS1/ADAMTS18/C1QTNF1/SERPINB2/APOE/THBD/PROCR/PDGFB | 22 |
| ANDERSEN_CHOLANGIOCARCINOMA_CLASS2 | ANDERSEN_CHOLANGIOCARCINOMA_CLASS2 | ANDERSEN_CHOLANGIOCARCINOMA_CLASS2 | 36/1438 | 175/23056 | 0.2057143 | 3.298295 | 7.871212 | 0.0000000 | 0.0000000 | 0.0000000 | SPOCD1/MTMR11/GPA33/LAMC2/LAMB3/CAPG/ITGB6/NRP2/COL6A3/CDCP1/ANXA3/PLAC8/ITGA2/COL12A1/SCIN/CTHRC1/CLIC3/DKK1/ANKRD22/ALDH3B1/MYEOV/STYK1/GPRC5A/BHLHE41/SIX4/PLEK2/MSLN/KRT15/KRT19/KRT17/HOXB7/SLC16A3/SERPINB2/KCNN4/KLK6/MXRA5 | 36 |
| GOBP_ANIMAL_ORGAN_FORMATION | GOBP_ANIMAL_ORGAN_FORMATION | GOBP_ANIMAL_ORGAN_FORMATION | 21/1438 | 65/23056 | 0.3230769 | 5.180015 | 8.703819 | 0.0000000 | 0.0000000 | 0.0000000 | TGFBR2/WNT5A/HES1/NKX3-2/GDNF/CITED2/HOXA3/GLI3/SHH/SULF1/EXT1/NOTCH1/DKK1/FGFR2/WT1/BMP4/SIX1/NOG/GATA6/BMP2/GATA5 | 21 |
| GOBP_CARDIAC_CHAMBER_DEVELOPMENT | GOBP_CARDIAC_CHAMBER_DEVELOPMENT | GOBP_CARDIAC_CHAMBER_DEVELOPMENT | 35/1438 | 167/23056 | 0.2095808 | 3.360289 | 7.895221 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/CCN1/TGFB2/BMP10/XIRP2/NRP2/TGFBR2/TNNC1/WNT5A/HEG1/HES1/FGFRL1/SLIT2/ADAMTS6/FOXC1/DSP/CITED2/ADGRG6/SEMA3C/FZD1/ZFPM2/TEK/NOTCH1/NRP1/FGFR2/BMP4/TPM1/SMAD6/SALL1/FOXF1/MYOCD/NOG/GATA6/TGFB1/BMP2 | 35 |
| KIM_WT1_TARGETS_8HR_UP | KIM_WT1_TARGETS_8HR_UP | KIM_WT1_TARGETS_8HR_UP | 35/1438 | 167/23056 | 0.2095808 | 3.360289 | 7.895221 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/LAMB3/DLX2/TM4SF1/WWTR1/IL1RAP/EREG/PDGFC/DAB2/HBEGF/ADAM19/GFPT2/ID4/TPBG/SYNJ2/SERPINE1/PODXL/ZYX/ST3GAL1/PHLDA2/ADM/WT1/CREB3L1/FOSL1/SERPINH1/EMP1/CA12/CSPG4/BCL2A1/IL4R/SOX9/IL11/SIRPA/DOK5/CSDC2 | 35 |
| GOBP_ENDODERM_DEVELOPMENT | GOBP_ENDODERM_DEVELOPMENT | GOBP_ENDODERM_DEVELOPMENT | 23/1438 | 78/23056 | 0.2948718 | 4.727791 | 8.505445 | 0.0000000 | 0.0000000 | 0.0000000 | LAMB3/ITGA4/COL5A2/FN1/COL7A1/COL8A1/ITGB5/COL12A1/INHBA/EXT1/COL5A1/NOTCH1/DKK1/ITGA5/ITGA7/HMGA2/MMP14/BMP4/ZFP36L1/MMP2/LHX1/NOG/GATA6 | 23 |
| IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | 30/1438 | 128/23056 | 0.2343750 | 3.757823 | 8.069425 | 0.0000000 | 0.0000000 | 0.0000000 | KYNU/ARHGAP24/SLC7A11/SERPINB1/TFAP2A/PSMB8/PSMB9/PTPRK/PDGFA/PTN/PLAT/HAS2/PTGR1/NEK6/SRGN/AIFM2/ACSL5/PHLDA2/CD44/FOSL1/CASP1/HMGA2/NID2/MT2A/MT1X/PSMB10/NQO1/MAF/COTL1/HMOX1 | 30 |
| SANA_TNF_SIGNALING_DN | SANA_TNF_SIGNALING_DN | SANA_TNF_SIGNALING_DN | 24/1438 | 85/23056 | 0.2823529 | 4.527072 | 8.402105 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/EFEMP1/ITGA6/CAVIN2/TM4SF1/KDR/GASK1B/DDR1/NT5E/CCN2/SASH1/CLU/ANXA1/MYOF/VWF/ARHGDIB/KRT7/PHLDA1/POSTN/AHNAK2/NQO1/PECAM1/TGM2/BGN | 24 |
| WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY | WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY | WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY | 18/1438 | 48/23056 | 0.3750000 | 6.012517 | 8.965847 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/WNT5A/EGF/FST/NT5E/PDGFA/IL6/INHBA/SHH/NOTCH1/DKK1/IGF1/BMP4/NOG/TGFB1/IL11/PDGFB/WNT7B | 18 |
| RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN | 52/1438 | 321/23056 | 0.1619938 | 2.597308 | 7.432721 | 0.0000000 | 0.0000000 | 0.0000000 | NLRP3/IL1B/ITGA4/SP110/SP140L/MITF/CXCL1/CXCL5/CXCL3/EREG/PLAC8/C9/IQGAP2/F2RL1/HBEGF/CCDC69/SPARC/HLA-E/PLA2G7/VNN1/SOD2/ADAM28/IDO1/ALOX5/MYOF/TCF7L2/IFITM2/NRIP3/MS4A4A/PLAAT4/CASP1/VWA5A/C3AR1/EMP1/BHLHE41/CPM/RAB20/SLC7A7/CES1/MT2A/MT1X/ABCC3/PECAM1/SLC16A5/C3/ZFP36/C5AR1/FPR1/RIN2/MX2/ARHGEF6/ZNF185 | 52 |
| GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | 25/1438 | 92/23056 | 0.2717391 | 4.356897 | 8.320748 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/FAP/TFPI/EPHA4/SERPINE2/PHLDB2/SPP1/ADTRP/EDN1/CD109/PDGFA/SERPINE1/PLAT/EPPK1/ALOX5/MYOZ1/PLAU/UBASH3B/THBS1/ADAMTS18/C1QTNF1/SERPINB2/APOE/THBD/PDGFB | 25 |
| GOCC_PROTEIN_COMPLEX_INVOLVED_IN_CELL_ADHESION | GOCC_PROTEIN_COMPLEX_INVOLVED_IN_CELL_ADHESION | GOCC_PROTEIN_COMPLEX_INVOLVED_IN_CELL_ADHESION | 17/1438 | 43/23056 | 0.3953488 | 6.338778 | 9.037404 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/ITGB6/ITGA6/ITGA4/ITGB5/ITGA2/ITGB8/ITGA8/PLAU/TSPAN32/ITGA5/ITGA7/ITGA11/ITGA3/ITGB4/LGALS2/LGALS1 | 17 |
| PID_INTEGRIN3_PATHWAY | PID_INTEGRIN3_PATHWAY | PID_INTEGRIN3_PATHWAY | 17/1438 | 43/23056 | 0.3953488 | 6.338778 | 9.037404 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/FN1/TGFBR2/KDR/SPP1/EDIL3/TGFBI/LAMA4/PLAU/THBS1/FBN1/COL1A1/PECAM1/SDC4/PDGFB/COL4A6/COL4A5 | 17 |
| MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_INDEPENDENT | MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_INDEPENDENT | MEBARKI_HCC_PROGENITOR_WNT_UP_CTNNB1_INDEPENDENT | 13/1438 | 24/23056 | 0.5416667 | 8.684747 | 9.714571 | 0.0000000 | 0.0000000 | 0.0000000 | SPOCD1/OLFML3/FAP/FN1/LRRC15/TGFBI/ADAM19/MDFI/PDGFRL/COL5A1/FBN1/MMP2/MRC2 | 13 |
| HP_ABNORMAL_PLEURA_MORPHOLOGY | HP_ABNORMAL_PLEURA_MORPHOLOGY | HP_ABNORMAL_PLEURA_MORPHOLOGY | 31/1438 | 137/23056 | 0.2262774 | 3.627991 | 7.956839 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/PTPN22/FCGR2A/LAMC2/CFH/LAMB3/TGFB2/COL3A1/TGFBR2/MYLK/BCL6/SLC34A2/ADAMTS3/SPP1/CFI/FAT4/ADAMTS2/HFE/IL6/EPHB4/EXT1/FAS/EFEMP2/TNFRSF1A/STAT6/FBLN5/FBN1/FOXF1/PIEZO1/PLVAP/BMP2 | 31 |
| WP_NETWORK_MAP_OF_SARSCOV2_SIGNALING_PATHWAY | WP_NETWORK_MAP_OF_SARSCOV2_SIGNALING_PATHWAY | WP_NETWORK_MAP_OF_SARSCOV2_SIGNALING_PATHWAY | 41/1438 | 221/23056 | 0.1855204 | 2.974518 | 7.606959 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/PTGS2/CFH/AGT/NLRP3/IL1A/IL1B/CASP8/FN1/TGFBR2/COL7A1/ITIH3/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/CFI/AHR/IL6/CCL26/SERPINE1/DDX58/GSN/NFKB2/IFITM3/HBD/SAA1/APOA1/C1S/C1R/IRF9/FOS/SERPINA10/CCL5/ITGA3/RRAS/CEBPB/MX1/APOL1 | 41 |
| HUANG_FOXA2_TARGETS_DN | HUANG_FOXA2_TARGETS_DN | HUANG_FOXA2_TARGETS_DN | 16/1438 | 38/23056 | 0.4210526 | 6.750897 | 9.150563 | 0.0000000 | 0.0000000 | 0.0000000 | ATP2B4/CXCL2/SPP1/CFI/TGFBI/SPARC/LOXL2/PLAT/CLIC3/COL13A1/CD44/IGFBP6/SMAD6/ITGB4/TGM2/GAS2L1 | 16 |
| BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_CELLS_UP | 24/1438 | 86/23056 | 0.2790698 | 4.474431 | 8.325431 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF9/GBP4/LAMC2/HSD11B1/IL1A/IL1B/CDCP1/TMEM156/CXCL8/EREG/CSF2/RUNX2/CRYBG1/IL6/BMPER/PTPRE/MMP10/MMP1/SPX/BCL2A1/SLFN5/CCL5/SERPINB7/ICAM1 | 24 |
| HOOI_ST7_TARGETS_UP | HOOI_ST7_TARGETS_UP | HOOI_ST7_TARGETS_UP | 25/1438 | 93/23056 | 0.2688172 | 4.310048 | 8.249274 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/NEXN/LAMB3/TGFA/EVA1A/ANXA3/FGF5/IL15/INPP4B/IL7R/IL31RA/ADAMTS6/SOX30/RUNX2/OGFRL1/ARHGAP18/ADGRG6/TRIP6/SERPINE1/FLNC/MEST/PODXL/JCAD/GLIPR1/IL32 | 25 |
| MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | 68/1438 | 485/23056 | 0.1402062 | 2.247979 | 7.164023 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/FBLIM1/MCOLN2/RHOC/PTPN22/PRRX1/PTGS2/HSD11B1/CRIM1/EFEMP1/TGFA/IL1B/GALNT3/MPP4/BHLHE40/HRH1/EPHA3/FSTL1/WWTR1/SPON2/JCHAIN/CXCL3/ARHGAP24/TLR3/F2RL1/EDIL3/GRAMD2B/SERPINB1/DSP/ID4/RUNX2/COL19A1/AHR/CD36/MDFIC/EBF2/FZD6/TMC1/ANXA1/GAS1/KLF4/IFITM2/CD44/PTPRJ/MS4A4A/AHNAK/SYTL2/PRSS23/KLRD1/KLRC4-KLRK1/EPS8/IGF1/LATS2/POSTN/FOS/MYO1E/BNC1/CCL5/CCR7/SOCS3/DSG2/KCNN4/CYP24A1/SIM2/IL2RB/CARD10/SAT1/CHST7 | 68 |
| GAURNIER_PSMD4_TARGETS | GAURNIER_PSMD4_TARGETS | GAURNIER_PSMD4_TARGETS | 22/1438 | 73/23056 | 0.3013699 | 4.831977 | 8.457369 | 0.0000000 | 0.0000000 | 0.0000000 | IL22RA1/IL1A/CCR3/CXCL8/CXCL6/CXCL1/CXCL3/CXCL2/HLA-E/HLA-C/IL6/NFKB2/C3AR1/IL21R/CCL5/CCR7/C3/IL12RB1/TGFB1/RELB/C5AR1/IL13RA1 | 22 |
| GOBP_MULTI_MULTICELLULAR_ORGANISM_PROCESS | GOBP_MULTI_MULTICELLULAR_ORGANISM_PROCESS | GOBP_MULTI_MULTICELLULAR_ORGANISM_PROCESS | 40/1438 | 213/23056 | 0.1877934 | 3.010963 | 7.604517 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/AGT/IL1B/SERPINE2/TGFBR2/SPP1/ITGA2/CRHBP/EDN1/DDR1/CLIC5/DDO/GJA1/CITED2/PTN/STC1/PNOC/IDO1/B4GALT1/PCSK5/PAPPA/HMX3/ADM/FOSL1/PGR/ARHGDIB/ITGA5/EPYC/FOS/MMP2/GIP/ITGA3/ITGB4/PSG5/PSG4/PSG9/PLA2G4C/THBD/LIF/NDP | 40 |
| GOBP_MONONUCLEAR_CELL_DIFFERENTIATION | GOBP_MONONUCLEAR_CELL_DIFFERENTIATION | GOBP_MONONUCLEAR_CELL_DIFFERENTIATION | 63/1438 | 434/23056 | 0.1451613 | 2.327426 | 7.200190 | 0.0000000 | 0.0000000 | 0.0000000 | RUNX3/ZC3H12A/VCAM1/CSF1/PTPN22/IFI16/MR1/PTPRC/ITPKB/NLRP3/CYP26B1/IL1A/IL1B/ITGB6/ITGA4/PPARG/TGFBR2/BCL6/LEF1/IL15/IL7R/IL31RA/F2RL1/CSF2/DOCK2/RUNX2/VNN1/ITGB8/IL6/HOXA7/INHBA/GLI3/SHH/ST3GAL1/IFNE/ANXA1/IL15RA/FZD8/HHEX/PTPRJ/NCKAP1L/TESPA1/STAT6/FLT3/TNFSF13B/MMP14/BMP4/ZFP36L1/IL4R/CCR7/TNFSF9/IL12RB1/AXL/PSG9/BCL3/RELB/IL4I1/IL11/CEBPB/RUNX1/MYH9/LGALS1/ITM2A | 63 |
| BROWNE_INTERFERON_RESPONSIVE_GENES | BROWNE_INTERFERON_RESPONSIVE_GENES | BROWNE_INTERFERON_RESPONSIVE_GENES | 21/1438 | 67/23056 | 0.3134328 | 5.025388 | 8.510191 | 0.0000000 | 0.0000000 | 0.0000000 | IFI44L/GBP1/GBP2/NMI/SP110/SP100/IL15/TLR3/GMPR/PSMB8/PSMB9/STX11/IDO1/IL15RA/PLAAT4/CASP1/OASL/IFI35/MX2/MX1/APOBEC3G | 21 |
| GOBP_ENDODERM_FORMATION | GOBP_ENDODERM_FORMATION | GOBP_ENDODERM_FORMATION | 19/1438 | 55/23056 | 0.3454545 | 5.538804 | 8.691679 | 0.0000000 | 0.0000000 | 0.0000000 | LAMB3/ITGA4/COL5A2/FN1/COL7A1/COL8A1/ITGB5/COL12A1/INHBA/COL5A1/DKK1/ITGA5/ITGA7/HMGA2/MMP14/MMP2/LHX1/NOG/GATA6 | 19 |
| LINDSTEDT_DENDRITIC_CELL_MATURATION_A | LINDSTEDT_DENDRITIC_CELL_MATURATION_A | LINDSTEDT_DENDRITIC_CELL_MATURATION_A | 20/1438 | 61/23056 | 0.3278689 | 5.256846 | 8.585990 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF4/GBP1/PLA2G4A/IL1B/KYNU/CXCL8/CXCL1/CXCL2/SLC7A11/IL7R/CSF2/EDN1/PLA2G7/SOD2/IL6/INHBA/PLAT/CCL5/TNFSF9/ICAM1 | 20 |
| GOBP_COLLAGEN_METABOLIC_PROCESS | GOBP_COLLAGEN_METABOLIC_PROCESS | GOBP_COLLAGEN_METABOLIC_PROCESS | 26/1438 | 101/23056 | 0.2574257 | 4.127405 | 8.123821 | 0.0000000 | 0.0000000 | 0.0000000 | MMP23B/ERRFI1/CTSS/FAP/P3H2/ADAMTS3/ITGA2/ADAMTS2/CCN2/IL6/COL5A1/CREB3L1/SERPINH1/MMP10/MMP1/MMP3/TNS2/MMP14/BMP4/MMP2/COL1A1/MRC2/SERPINB7/TGFB1/KLK6/RUNX1 | 26 |
| KEGG_HEMATOPOIETIC_CELL_LINEAGE | KEGG_HEMATOPOIETIC_CELL_LINEAGE | KEGG_HEMATOPOIETIC_CELL_LINEAGE | 24/1438 | 87/23056 | 0.2758621 | 4.423001 | 8.249923 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/CD34/IL1R1/IL1A/IL1B/ITGA6/ITGA4/MME/GYPA/IL7R/ITGA2/CSF2/IL6/CD36/CD44/ITGA5/FLT3/ANPEP/IL4R/CSF3/ITGA3/CD22/CD37/IL11 | 24 |
| GOMF_GROWTH_FACTOR_RECEPTOR_BINDING | GOMF_GROWTH_FACTOR_RECEPTOR_BINDING | GOMF_GROWTH_FACTOR_RECEPTOR_BINDING | 31/1438 | 139/23056 | 0.2230216 | 3.575790 | 7.855850 | 0.0000000 | 0.0000000 | 0.0000000 | ECM1/EFEMP1/TGFA/IL1R1/IL1A/IL1B/IL36G/IL1RAP/EPGN/EREG/BTC/FGF5/EGF/PDGFC/VEGFC/GDNF/TSLP/CSF2/HBEGF/FGF18/PDGFA/IL6/TRIP6/FGF20/PTPRJ/ITGA5/CSF3/IL27RA/IL12RB1/IL11/PDGFB | 31 |
| TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_DN | 22/1438 | 74/23056 | 0.2972973 | 4.766680 | 8.370183 | 0.0000000 | 0.0000000 | 0.0000000 | PRRX1/COL3A1/COL5A2/FN1/COL6A3/COL8A1/LRRC15/SPP1/CAP2/COL12A1/THBS2/CTHRC1/CCN4/EPPK1/COL5A1/POSTN/FBN1/MMP2/COL1A1/C5AR1/MXRA5/BGN | 22 |
| GOBP_PROTEIN_PROCESSING | GOBP_PROTEIN_PROCESSING | GOBP_PROTEIN_PROCESSING | 43/1438 | 242/23056 | 0.1776860 | 2.848906 | 7.457206 | 0.0000000 | 0.0000000 | 0.0000000 | ECE1/HJV/CTSS/S100A10/IFI16/DPP4/CASP8/SERPINE2/MME/ADAMTS3/NKD2/PCSK1/ADAM19/ADAMTS2/PLA2G7/PERP/GLI3/SERPINE1/SHH/PLAT/ASPH/PCSK5/GAS1/GSN/SRGN/PLAU/NLRP6/MYRF/CASP4/CASP1/CARD16/C1R/C1RL/CPM/MMP14/THBS1/ANXA2/KLK6/PRNP/RUNX1/BACE2/GGT1/MYH9 | 43 |
| AMIT_EGF_RESPONSE_60_MCF10A | AMIT_EGF_RESPONSE_60_MCF10A | AMIT_EGF_RESPONSE_60_MCF10A | 16/1438 | 39/23056 | 0.4102564 | 6.577797 | 8.991350 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/CCN1/PTGS2/ITGB6/BHLHE40/HES1/CXCL8/CXCL2/PLK2/IER3/CCN2/TNFAIP3/IL6/INHBA/GLIPR1/TPM1 | 16 |
| GOBP_NERVE_DEVELOPMENT | GOBP_NERVE_DEVELOPMENT | GOBP_NERVE_DEVELOPMENT | 23/1438 | 81/23056 | 0.2839506 | 4.552688 | 8.260875 | 0.0000000 | 0.0000000 | 0.0000000 | ECE1/VCAM1/ITGA4/NRP2/SERPINE2/ACKR3/HES1/TFAP2A/EDN1/CITED2/HOXA1/HOXA3/GLI3/SEMA3A/SULF1/EXT1/NRP1/SIX1/SIX4/SLC24A4/SALL1/HOXB2/HOXB3 | 23 |
| GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | 30/1438 | 132/23056 | 0.2272727 | 3.643950 | 7.856864 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/PTGS2/AGT/NRP2/WNT5A/KDR/ANXA3/EGF/VEGFC/SEMA5A/PLK2/SPARC/FGF18/EDN1/SASH1/MET/ANGPT1/TEK/ANXA1/JCAD/NRP1/PRKD1/BMP4/THBS1/TGFB1/RRAS/RIN2/HMOX1/PDGFB/SRPX2 | 30 |
| RUIZ_TNC_TARGETS_UP | RUIZ_TNC_TARGETS_UP | RUIZ_TNC_TARGETS_UP | 33/1438 | 156/23056 | 0.2115385 | 3.391676 | 7.730387 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/VCAM1/ATP2B4/IL1R1/HNMT/COL3A1/COL5A2/TM4SF1/BCL6/SPP1/LEF1/TDO2/SEMA5A/PLK2/IQGAP2/SNCAIP/SEMA3C/CSGALNACT1/CLU/ST3GAL1/GSN/JCAD/ZCCHC24/PLAAT4/C1RL/FOXF1/WIPI1/GPRC5C/GDF15/APOE/COL18A1/SAT1/COL4A5 | 33 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | 33/1438 | 156/23056 | 0.2115385 | 3.391676 | 7.730387 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/IFI44L/GBP1/PTGS2/CAVIN2/SLC12A8/JCHAIN/DDX60/TSLP/FGF18/FOXC1/RHAG/GJA1/HOXA3/HOXA7/RBPMS/IDO1/ANGPT1/DDX58/HBD/PRSS23/SLC6A13/KRT18/METTL7B/FLT3/THBS1/CCR7/HOXB3/NOG/GDF15/MX2/MX1/USP18 | 33 |
| GOBP_PLACENTA_DEVELOPMENT | GOBP_PLACENTA_DEVELOPMENT | GOBP_PLACENTA_DEVELOPMENT | 32/1438 | 148/23056 | 0.2162162 | 3.466677 | 7.764326 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/PTGS2/CASP8/PPARG/MME/HES1/SPP1/LEF1/CSF2/ADAM19/MDFI/GCM1/RSPO3/CITED2/ITGB8/PTN/STC1/FGFR2/HTRA1/PHLDA2/ADM/FOSL1/ZFP36L1/ESRRB/KRT19/DLX3/SOCS3/CEBPB/LIF/PDGFB/WNT7B/NDP | 32 |
| CHIBA_RESPONSE_TO_TSA_UP | CHIBA_RESPONSE_TO_TSA_UP | CHIBA_RESPONSE_TO_TSA_UP | 18/1438 | 50/23056 | 0.3600000 | 5.772017 | 8.712056 | 0.0000000 | 0.0000000 | 0.0000000 | SOD3/VEGFC/HBEGF/BMP6/CCN2/CD36/TRIP6/CAV2/ARHGDIB/KRT7/ITGA7/LUM/BMP4/FOS/KRT19/JUP/ITGA3/TGFB1 | 18 |
| GOBP_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | 18/1438 | 50/23056 | 0.3600000 | 5.772017 | 8.712056 | 0.0000000 | 0.0000000 | 0.0000000 | WNT9A/EFEMP1/RARB/NKX3-2/ADAMTS12/FGF18/BMP6/RUNX2/CCN2/SCIN/GLI3/LOXL2/GDF6/TRPS1/CCN4/BMP4/MAF/SOX9 | 18 |
| SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | 18/1438 | 50/23056 | 0.3600000 | 5.772017 | 8.712056 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/COL5A2/LAMB2/FSTL1/AMOTL2/EDN1/ID4/DDR1/CCN2/CEBPD/TNFRSF11B/TAGLN/TNFRSF1A/LTBP2/FBLN5/FBN1/COL1A1/BGN | 18 |
| TSUNODA_CISPLATIN_RESISTANCE_DN | TSUNODA_CISPLATIN_RESISTANCE_DN | TSUNODA_CISPLATIN_RESISTANCE_DN | 18/1438 | 50/23056 | 0.3600000 | 5.772017 | 8.712056 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/KYNU/CPS1/FN1/WNT5A/NPR3/ELL2/CLU/TCIM/B4GALT1/ANXA8L1/C1S/KRT7/CRIP1/FBN1/FSTL3/C3/MAGEA9 | 18 |
| PEREZ_TP53_AND_TP63_TARGETS | PEREZ_TP53_AND_TP63_TARGETS | PEREZ_TP53_AND_TP63_TARGETS | 39/1438 | 207/23056 | 0.1884058 | 3.020782 | 7.532259 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/RASSF5/LBH/SLIT2/FGF18/ID4/MOXD1/SASH1/MICALL2/C7orf57/FZD1/GPR37/EPPK1/AQP3/PCSK5/COL27A1/ZCCHC24/PTPRJ/ELMOD1/CRYAB/NUAK1/ZIC2/CGNL1/SMAD6/SOX8/MAF/CRISPLD2/FOXF1/ADAP2/METRNL/PLIN4/BMP2/COL9A3/MX1/COL18A1/WNT7B/MXRA5/ARHGEF6/GABRE | 39 |
| GOBP_MYELOID_LEUKOCYTE_ACTIVATION | GOBP_MYELOID_LEUKOCYTE_ACTIVATION | GOBP_MYELOID_LEUKOCYTE_ACTIVATION | 42/1438 | 234/23056 | 0.1794872 | 2.877786 | 7.446144 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/EDN2/CSF1/S100A13/PLA2G4A/PTPRC/NMI/ITGB6/FN1/TGFBR2/WNT5A/SUCNR1/CXCL8/CXCL6/ANXA3/IL15/TLR3/IL31RA/F2RL1/TSLP/CSF2/DOCK2/ADGRF5/ITGB8/IL6/CLU/ADAM9/ANXA1/TSPAN32/LRFN5/THBS1/IL4R/LAT/FOXF1/CCL5/IFI35/MILR1/NECTIN2/RELB/C5AR1/HMOX1/RAC2 | 42 |
| GERHOLD_ADIPOGENESIS_DN | GERHOLD_ADIPOGENESIS_DN | GERHOLD_ADIPOGENESIS_DN | 20/1438 | 62/23056 | 0.3225806 | 5.172058 | 8.483854 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/ECM1/IL1R1/CASP8/FN1/ANXA3/IER3/CCN2/THBS2/PLAT/CEBPD/GAS1/CD44/CRYAB/MMP14/TNFAIP2/THBS1/ANXA2/IL4R/THBD | 20 |
| GOBP_EPITHELIAL_CELL_DEVELOPMENT | GOBP_EPITHELIAL_CELL_DEVELOPMENT | GOBP_EPITHELIAL_CELL_DEVELOPMENT | 39/1438 | 208/23056 | 0.1875000 | 3.006259 | 7.496331 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ADAMTSL4/IL1A/IL1B/RARB/LAMB2/WNT5A/HEG1/CLDN1/NKX3-2/F2RL1/BMP6/ROS1/GJA1/MET/PODXL/STC1/B4GALT1/S1PR3/NOTCH1/VCL/PGR/YAP1/ROBO4/TNFRSF1A/EDNRB/FRMD6/BMP4/MYO1E/SOX8/HOXB13/PECAM1/SOX9/ICAM1/BFSP1/COL18A1/PDGFB/WNT7B/MSN | 39 |
| HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 65/1438 | 461/23056 | 0.1409978 | 2.260672 | 7.051809 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/FUCA1/CFH/CYP26B1/DLX2/ITGA6/TFPI/NABP1/FN1/SERPINE2/EPHA3/SLC12A8/BCL6/HES1/FGFR3/SPP1/IL15/PLK2/GMPR/IER3/LGSN/MICALL2/AHR/HOXA1/TRIP6/MET/TSPAN12/PDGFRL/MYBL1/COL14A1/GSN/PAEP/AKR1C3/MYOF/PHLDA2/MICAL2/BIRC3/C1S/KRT18/ITGA7/FOS/AHNAK2/FBN1/TPM1/ALDH1A3/MT2A/MT1X/RRAD/COTL1/CRISPLD2/JUP/SLC16A3/C3/KLF2/APOE/RRAS/SDC4/TFAP2C/COL6A2/SAT1/SSX1/SSX2/IL13RA1/TENM1/MAGEA9 | 65 |
| GOBP_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 64/1438 | 451/23056 | 0.1419069 | 2.275247 | 7.053985 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF4/ZC3H12A/RNF220/GFI1/TNFSF18/RAB7B/IKBKE/AGT/NLRP3/IL1B/SP100/BHLHE40/IRAK2/PPARG/WNT5A/IL1RAP/HES1/ANXA3/TLR3/TRIML2/TRIML1/STING1/EDN1/TRIM38/MDFI/TNFAIP3/IL6/GLI3/CD36/FZD1/CAV1/ARHGEF5/SHH/CLU/FZD6/ADCY8/PARP10/DDX58/KLF4/TRAF1/TCF7L2/FANK1/TRIM5/FOSL1/FZD4/CARD16/WNT10B/GLI1/ZIC2/PRKD1/NFKBIA/NUPR1/NLRC5/MYOCD/CSF3/JUP/TNFRSF11A/BCL3/PRNP/BMP2/FOXS1/PTGIS/HMOX1/NDP | 64 |
| ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP | 28/1438 | 118/23056 | 0.2372881 | 3.804531 | 7.877306 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/GBP4/VCAM1/CD53/CTSS/IFI16/SHISA5/UBA7/CXCL2/PLAC8/PSMB8/PSMB9/TAPBP/CRYBG1/MSR1/PTGS1/FAS/MS4A4A/KRT18/NFKBIA/SERPINA10/BCL2A1/PSMB10/IFI35/ADGRE1/ICAM1/PROCR/USP18 | 28 |
| HALLMARK_COMPLEMENT | HALLMARK_COMPLEMENT | HALLMARK_COMPLEMENT | 38/1438 | 200/23056 | 0.1900000 | 3.046342 | 7.496307 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/CTSS/S100A13/PLA2G4A/CFH/KYNU/DPP4/CASP10/FN1/CXCL1/CTSO/C9/ERAP2/PSMB9/PLA2G7/TNFAIP3/IL6/CD36/SERPINE1/CLU/ADAM9/PLAT/ZFPM2/CASP4/CASP1/C1S/C1R/CPM/MMP14/SERPINA1/CDH13/CCL5/GNGT2/SERPINB2/C3/CEBPB/APOBEC3G/PDGFB | 38 |
| REACTOME_O_LINKED_GLYCOSYLATION | REACTOME_O_LINKED_GLYCOSYLATION | REACTOME_O_LINKED_GLYCOSYLATION | 27/1438 | 111/23056 | 0.2432432 | 3.900011 | 7.898987 | 0.0000000 | 0.0000000 | 0.0000000 | ADAMTSL4/GALNT5/GALNT3/GALNT15/MUC13/SPON2/ADAMTS3/GALNTL6/ADAMTS16/SEMA5A/ADAMTS12/ADAMTS6/GALNT10/ADAMTS2/THBS2/GALNT17/ST3GAL1/GALNT18/ADAMTS8/ADAMTS15/GALNT9/THBS1/ADAMTS18/ADAMTSL5/MUC16/B3GNT3/ADAMTS5 | 27 |
| GOBP_TISSUE_REMODELING | GOBP_TISSUE_REMODELING | GOBP_TISSUE_REMODELING | 35/1438 | 175/23056 | 0.2000000 | 3.206676 | 7.557434 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/TIE1/S1PR1/ELF3/AGT/IL1A/PPARG/MITF/SPP1/IL15/ADRB2/FOXC1/GJA1/RSPO3/TNFAIP3/IL6/GPNMB/HOXA3/SEMA3C/PDK4/CAV1/PTN/CTHRC1/EXT1/TNFRSF11B/UBASH3B/MMP14/CSPG4/MMP2/SIGLEC15/TNFRSF11A/AXL/TGFB1/RUNX1/LIF | 35 |
| REACTOME_MET_ACTIVATES_PTK2_SIGNALING | REACTOME_MET_ACTIVATES_PTK2_SIGNALING | REACTOME_MET_ACTIVATES_PTK2_SIGNALING | 14/1438 | 30/23056 | 0.4666667 | 7.482244 | 9.162859 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/LAMB3/COL3A1/COL5A2/FN1/LAMB2/ITGA2/LAMA4/LAMA2/MET/COL27A1/COL5A1/ITGA3/COL1A1 | 14 |
| NABA_BASEMENT_MEMBRANES | NABA_BASEMENT_MEMBRANES | NABA_BASEMENT_MEMBRANES | 16/1438 | 40/23056 | 0.4000000 | 6.413352 | 8.837625 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/HSPG2/LAMC2/HMCN1/LAMB3/NID1/COL6A3/LAMB2/NPNT/LAMA4/LAMA2/NID2/COL18A1/COL6A2/COL4A6/COL4A5 | 16 |
| GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_UP | 40/1438 | 219/23056 | 0.1826484 | 2.928471 | 7.395541 | 0.0000000 | 0.0000000 | 0.0000000 | GBP2/CSF1/PRELP/HSD11B1/OSR1/COL3A1/COL5A2/SP110/SP100/UBA7/PHLDB2/FSTL1/PARP14/RTP4/EGF/DDX60/TLR3/RNF144B/HLA-E/SOD2/AQP1/MEST/PARP12/ANGPT1/NXNL2/NACC2/FAS/TRIM5/PRSS23/NNMT/IRF9/PSMB10/IFI35/HOXB7/C3/RIN2/MX1/USP18/APOL3/BGN | 40 |
| NAKAMURA_ADIPOGENESIS_LATE_DN | NAKAMURA_ADIPOGENESIS_LATE_DN | NAKAMURA_ADIPOGENESIS_LATE_DN | 15/1438 | 35/23056 | 0.4285714 | 6.871448 | 8.965436 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/ACTG2/SERPINE2/RAI14/HAPLN1/EDIL3/NT5E/THBS2/SERPINE1/GLIPR1/POSTN/TPM1/ITGA3/GDF15/COL9A3 | 15 |
| GOBP_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | GOBP_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | GOBP_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | 24/1438 | 90/23056 | 0.2666667 | 4.275568 | 8.030072 | 0.0000000 | 0.0000000 | 0.0000000 | CSF1/ITGB6/DLX1/DLX2/AMTN/ENAM/LEF1/FST/FOXC1/RUNX2/PERP/FAM20C/GLI3/SERPINE1/SHH/RSPO2/TNFRSF11B/HTRA1/ADM/BMP4/SLC24A4/DLX3/GATA6/BMP2 | 24 |
| GOBP_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_CANONICAL_WNT_SIGNALING_PATHWAY | 50/1438 | 313/23056 | 0.1597444 | 2.561243 | 7.172540 | 0.0000000 | 0.0000000 | 0.0000000 | RNF220/LGR6/WNT9A/WNT5A/MITF/WWTR1/LEF1/EGF/NKD2/SEMA5A/DAB2/EDN1/TPBG/TBX18/RSPO3/GLI3/HECW1/FZD1/CAV1/SHH/ZNF703/FZD6/CTHRC1/RSPO2/EXT1/KLF4/NOTCH1/FZD8/DKK1/HHEX/TCF7L2/FGFR2/FZD4/YAP1/BCL9L/WNT10B/IGFBP6/GLI1/LATS2/FOXO1/EDNRB/DACT1/JUP/COL1A1/NOG/SOX9/TGFB1/APOE/BMP2/WNT7B | 50 |
| GOBP_POSITIVE_REGULATION_OF_LIPID_LOCALIZATION | GOBP_POSITIVE_REGULATION_OF_LIPID_LOCALIZATION | GOBP_POSITIVE_REGULATION_OF_LIPID_LOCALIZATION | 27/1438 | 112/23056 | 0.2410714 | 3.865190 | 7.839387 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/ZC3H12A/PLA2G4A/IKBKE/IL1A/IL1B/PPARG/SPP1/DAB2/BMP6/EDN1/CD36/CAV1/MSR1/ACSL5/APOA1/NFKBIA/CYP19A1/ANXA2/CES1/CETP/ABCA8/C1QTNF1/LIPG/TNFRSF11A/C3/APOE | 27 |
| KONDO_EZH2_TARGETS | KONDO_EZH2_TARGETS | KONDO_EZH2_TARGETS | 41/1438 | 229/23056 | 0.1790393 | 2.870605 | 7.337189 | 0.0000000 | 0.0000000 | 0.0000000 | CNIH3/OSR1/NPAS2/DLX2/ITGA6/TFPI/COL3A1/AOX1/DNER/IQCA1/ACKR2/COL8A1/MYLK/MGLL/WWTR1/CXCL5/EDIL3/SPARC/EDN1/CAP2/RNF144B/NT5E/GJA1/CCN2/UST/SERPINE1/FABP4/HAS2/ST3GAL1/MAP3K8/NRP1/LOXL4/MMP1/NNMT/C1S/EMP1/CYP19A1/BCL2A1/COL1A1/KLF2/IL13RA1 | 41 |
| GOBP_ENDODERMAL_CELL_DIFFERENTIATION | GOBP_ENDODERMAL_CELL_DIFFERENTIATION | GOBP_ENDODERMAL_CELL_DIFFERENTIATION | 17/1438 | 46/23056 | 0.3695652 | 5.925380 | 8.624115 | 0.0000000 | 0.0000000 | 0.0000000 | LAMB3/ITGA4/COL5A2/FN1/COL7A1/COL8A1/ITGB5/COL12A1/INHBA/COL5A1/DKK1/ITGA5/ITGA7/HMGA2/MMP14/MMP2/GATA6 | 17 |
| REACTOME_INTERLEUKIN_10_SIGNALING | REACTOME_INTERLEUKIN_10_SIGNALING | REACTOME_INTERLEUKIN_10_SIGNALING | 17/1438 | 46/23056 | 0.3695652 | 5.925380 | 8.624115 | 0.0000000 | 0.0000000 | 0.0000000 | TNFRSF1B/CSF1/PTGS2/IL1R1/IL1A/IL1B/CXCL8/CXCL1/CXCL2/CSF2/IL6/TNFRSF1A/CCL5/CSF3/ICAM1/FPR1/LIF | 17 |
| GOBP_POSITIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 28/1438 | 120/23056 | 0.2333333 | 3.741122 | 7.764516 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/TGFB2/BMP10/PPARG/TGFBR2/HES1/KDR/BMP3/NPNT/DAB2/FOXD1/BMP6/HFE/CITED2/INHBA/RBPMS/SULF1/GDF6/CRB2/NOTCH1/ITGA8/BMP4/THBS1/MYOCD/GATA6/GDF15/TGFB1/BMP2 | 28 |
| GOBP_REGULATION_OF_BMP_SIGNALING_PATHWAY | GOBP_REGULATION_OF_BMP_SIGNALING_PATHWAY | GOBP_REGULATION_OF_BMP_SIGNALING_PATHWAY | 26/1438 | 105/23056 | 0.2476190 | 3.970170 | 7.867367 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/HJV/CRIM1/DLX1/PPARG/WNT5A/FSTL1/HES1/KDR/FST/FOXD1/BMPER/FZD1/SULF1/CRB2/NOTCH1/DKK1/HTRA1/BMP4/FBN1/RBPMS2/SMAD6/ITGA3/NOG/GATA6/FSTL3 | 26 |
| GOBP_MESONEPHRIC_TUBULE_MORPHOGENESIS | GOBP_MESONEPHRIC_TUBULE_MORPHOGENESIS | GOBP_MESONEPHRIC_TUBULE_MORPHOGENESIS | 20/1438 | 64/23056 | 0.3125000 | 5.010431 | 8.286038 | 0.0000000 | 0.0000000 | 0.0000000 | AGT/OSR1/HES1/NPNT/ADAMTS16/GDNF/FOXD1/GLI3/SHH/WT1/BMP4/SIX1/SIX4/SOX8/SALL1/LHX1/HOXB7/NOG/SOX9/BMP2 | 20 |
| GOBP_NEPHRON_MORPHOGENESIS | GOBP_NEPHRON_MORPHOGENESIS | GOBP_NEPHRON_MORPHOGENESIS | 22/1438 | 77/23056 | 0.2857143 | 4.580966 | 8.117722 | 0.0000000 | 0.0000000 | 0.0000000 | AGT/OSR1/HES1/NPNT/IRX2/ADAMTS16/GDNF/FOXD1/GLI3/SHH/WT1/BMP4/SIX1/SIX4/SOX8/SALL1/LHX1/HOXB7/NOG/SOX9/BMP2/LIF | 22 |
| GOBP_APPENDAGE_DEVELOPMENT | GOBP_APPENDAGE_DEVELOPMENT | GOBP_APPENDAGE_DEVELOPMENT | 35/1438 | 177/23056 | 0.1977401 | 3.170442 | 7.476023 | 0.0000000 | 0.0000000 | 0.0000000 | ECE1/CRABP2/PRRX1/TGFB2/OSR1/CYP26B1/ITGA6/SP9/COL3A1/RARB/WNT5A/LEF1/SLC7A11/TFAP2A/RUNX2/GJA1/GLI3/SEMA3C/SHH/ASPH/FZD6/RSPO2/EXT1/PCSK5/NOTCH1/DKK1/FGFR2/ALX4/FREM2/BMP4/ALDH1A2/SALL1/NOG/SOX9/ITGB4 | 35 |
| GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | 13/1438 | 26/23056 | 0.5000000 | 8.016690 | 9.232647 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/FN1/TGFBR2/CAV1/MET/NRP1/VCL/CD44/PRSS23/CASP1/NQO1/COL18A1/IL13RA1 | 13 |
| PID_INTEGRIN_CS_PATHWAY | PID_INTEGRIN_CS_PATHWAY | PID_INTEGRIN_CS_PATHWAY | 13/1438 | 26/23056 | 0.5000000 | 8.016690 | 9.232647 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/ITGB6/ITGA6/ITGA4/ITGB5/ITGA2/ITGB8/ITGA8/ITGA5/ITGA7/ITGA11/ITGA3/ITGB4 | 13 |
| GOBP_BONE_MORPHOGENESIS | GOBP_BONE_MORPHOGENESIS | GOBP_BONE_MORPHOGENESIS | 25/1438 | 98/23056 | 0.2551020 | 4.090148 | 7.906414 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/CYP26B1/COL3A1/RARB/TGFBR2/FGFR3/FGF18/FOXC1/BMP6/TFAP2A/RUNX2/CITED2/GLI3/CSGALNACT1/STC1/EXT1/HAS2/COL27A1/COL13A1/FGFR2/SERPINH1/MMP14/BMP4/COL1A1/SOX9 | 25 |
| KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP | KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP | KIM_RESPONSE_TO_TSA_AND_DECITABINE_UP | 30/1438 | 136/23056 | 0.2205882 | 3.536775 | 7.652412 | 0.0000000 | 0.0000000 | 0.0000000 | CDA/FUCA1/S100A2/LAMC2/LAMB3/COL3A1/CDCP1/MUC13/ARL14/IL1RAP/F2RL1/TPD52L1/CLU/AQP3/CLIC3/PLAAT3/KRT7/CLDN7/KRT19/KRT17/PECAM1/CD70/CNN1/GDF15/TGM2/CYP24A1/SAT1/SSX1/SSX2/MAGEA9 | 30 |
| AMIT_SERUM_RESPONSE_60_MCF10A | AMIT_SERUM_RESPONSE_60_MCF10A | AMIT_SERUM_RESPONSE_60_MCF10A | 19/1438 | 58/23056 | 0.3275862 | 5.252314 | 8.362739 | 0.0000000 | 0.0000000 | 0.0000000 | ZC3H12A/CCN1/PTGS2/NUAK2/CYBRD1/FN1/BHLHE40/VGLL3/TM4SF1/CXCL8/EREG/PLK2/ELL2/HBEGF/CCN2/TNFAIP3/INHBA/GAS1/MAP3K8 | 19 |
| LEE_EARLY_T_LYMPHOCYTE_DN | LEE_EARLY_T_LYMPHOCYTE_DN | LEE_EARLY_T_LYMPHOCYTE_DN | 19/1438 | 58/23056 | 0.3275862 | 5.252314 | 8.362739 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/GBP2/S1PR1/TRABD2A/HLA-E/SAMD3/IFITM2/CD44/PTPRJ/AMIGO2/FOXO1/IL4R/NLRC5/COTL1/CCR7/IL27RA/KLF2/EMP3/NFATC2 | 19 |
| GOBP_ACUTE_INFLAMMATORY_RESPONSE | GOBP_ACUTE_INFLAMMATORY_RESPONSE | GOBP_ACUTE_INFLAMMATORY_RESPONSE | 27/1438 | 113/23056 | 0.2389381 | 3.830985 | 7.780471 | 0.0000000 | 0.0000000 | 0.0000000 | VCAM1/PTGS2/NLRP3/IL1A/IL1B/FN1/OSMR/IL31RA/HLA-E/VNN1/IL6/EXT1/B4GALT1/MBL2/NLRP6/SAA1/ALOX5AP/EDNRB/SERPINA1/NUPR1/MYLK3/CCR7/TNFRSF11A/ELANE/CREB3L3/C3/CEBPB | 27 |
| HALLMARK_APOPTOSIS | HALLMARK_APOPTOSIS | HALLMARK_APOPTOSIS | 33/1438 | 161/23056 | 0.2049689 | 3.286345 | 7.508248 | 0.0000000 | 0.0000000 | 0.0000000 | RNASEL/TGFB2/IL1A/IL1B/CASP8/EREG/LEF1/IER3/SOD2/IL6/CAV1/CLU/PLAT/ANXA1/GSN/FAS/IFITM3/CD44/BIRC3/CASP4/CASP1/EMP1/KRT18/IGFBP6/LUM/BMF/TNFRSF12A/MMP2/GADD45B/BMP2/HMOX1/SAT1/BGN | 33 |
| DER_IFN_GAMMA_RESPONSE_UP | DER_IFN_GAMMA_RESPONSE_UP | DER_IFN_GAMMA_RESPONSE_UP | 21/1438 | 71/23056 | 0.2957746 | 4.742267 | 8.145091 | 0.0000000 | 0.0000000 | 0.0000000 | GBP1/RHOC/IFI16/NMI/CASP8/SP110/VEGFC/HLA-E/HLA-C/PSMB8/PSMB9/IL6/CEBPD/IL15RA/FAS/FOSL1/C1S/IRF9/PSMB10/IFI35/ICAM1 | 21 |
| GOBP_LIPID_LOCALIZATION | GOBP_LIPID_LOCALIZATION | GOBP_LIPID_LOCALIZATION | 65/1438 | 469/23056 | 0.1385928 | 2.222110 | 6.896389 | 0.0000000 | 0.0000000 | 0.0000000 | LDLRAP1/ZC3H12A/CRABP2/PLA2G4A/IKBKE/AGT/IL1A/IL1B/PPARG/OSBPL10/SLCO2A1/ESYT3/PLSCR4/PLSCR2/CDS1/SPP1/ABCG2/EGF/DAB2/ATP10B/BMP6/EDN1/IL6/INHBA/CD36/CAV1/MEST/SHH/MSR1/CLU/FABP4/ANXA1/ACSL5/SLCO2B1/FZD4/APOC3/APOA1/SPX/SOAT2/SLC10A2/LRP10/NFKBIA/THBS1/TNFAIP8L3/CYP19A1/ANXA2/CES1/CETP/PITPNM3/ABCC3/ABCA8/ABCA9/ABCA6/ABCA10/C1QTNF1/LIPG/TNFRSF11A/ATP8B3/C3/KCNN4/APOE/PLA2G4C/APOL6/APOL3/APOL1 | 65 |
| GOBP_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | GOBP_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | GOBP_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | 31/1438 | 145/23056 | 0.2137931 | 3.427826 | 7.563691 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/AGT/IL1B/NMI/WNT5A/SUCNR1/IL15/TLR3/OSMR/ITGA2/TSLP/HLA-E/GPSM3/PLA2G7/IL6/SERPINE1/IDO1/FABP4/CCN4/CASP1/TNFRSF1A/ALOX5AP/NFKBIA/NUPR1/CCR7/IFI35/TNFRSF11A/CREB3L3/C3/CEBPB/LGALS1 | 31 |
| GOBP_REGULATION_OF_MAP_KINASE_ACTIVITY | GOBP_REGULATION_OF_MAP_KINASE_ACTIVITY | GOBP_REGULATION_OF_MAP_KINASE_ACTIVITY | 36/1438 | 187/23056 | 0.1925134 | 3.086640 | 7.389227 | 0.0000000 | 0.0000000 | 0.0000000 | PTPN22/PTPRC/LAX1/AGT/TGFA/IL1B/EPHA4/PPARG/WNT5A/EPGN/EGF/PDGFC/FGF18/EDN1/TPD52L1/SASH1/PDGFA/CAV1/ARHGEF5/ADAM9/FZD8/DKK1/PTPRJ/FZD4/FLT3/FLT1/AJUBA/BMP4/THBS1/TNFRSF11A/ELANE/TGFB1/APOE/BMP2/PDGFB/TENM1 | 36 |
| GOCC_INTEGRIN_COMPLEX | GOCC_INTEGRIN_COMPLEX | GOCC_INTEGRIN_COMPLEX | 14/1438 | 31/23056 | 0.4516129 | 7.240881 | 8.967702 | 0.0000000 | 0.0000000 | 0.0000000 | ITGA10/ITGB6/ITGA6/ITGA4/ITGB5/ITGA2/ITGB8/ITGA8/TSPAN32/ITGA5/ITGA7/ITGA11/ITGA3/ITGB4 | 14 |
| WP_OLIGODENDROCYTE_SPECIFICATION_AND_DIFFERENTIATION_LEADING_TO_MYELIN_COMPONENTS_FOR_CNS | WP_OLIGODENDROCYTE_SPECIFICATION_AND_DIFFERENTIATION_LEADING_TO_MYELIN_COMPONENTS_FOR_CNS | WP_OLIGODENDROCYTE_SPECIFICATION_AND_DIFFERENTIATION_LEADING_TO_MYELIN_COMPONENTS_FOR_CNS | 14/1438 | 31/23056 | 0.4516129 | 7.240881 | 8.967702 | 0.0000000 | 0.0000000 | 0.0000000 | IL1B/CXCL1/CXCL2/MOG/SHH/IGF1/BMP4/SOX8/SOX9/MBP/MAG/BMP2/LIF/PDGFB | 14 |
| ONDER_CDH1_TARGETS_1_DN | ONDER_CDH1_TARGETS_1_DN | ONDER_CDH1_TARGETS_1_DN | 34/1438 | 170/23056 | 0.2000000 | 3.206676 | 7.447874 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/TGFA/IL1B/IL36G/CASP8/SP100/CXCL8/CXCL1/CXCL3/CXCL2/IL7R/OSMR/FST/CSF2/HBEGF/SERPINB1/EDN1/MEST/CEMIP2/DKK1/EHF/FOSL1/P2RY2/MMP10/GPRC5A/KRT8/GLIPR1/NAV3/CSF3/KRT13/KRT15/SOX9/SERPINB2/SERPINB8 | 34 |
| GOMF_PROTEOGLYCAN_BINDING | GOMF_PROTEOGLYCAN_BINDING | GOMF_PROTEOGLYCAN_BINDING | 15/1438 | 36/23056 | 0.4166667 | 6.680575 | 8.797213 | 0.0000000 | 0.0000000 | 0.0000000 | AGRN/CTSS/CFH/PTPRC/NID1/FN1/SLIT2/SEMA5A/ITGA2/FST/GPNMB/FGF20/COL5A1/THBS1/APOE | 15 |
| HP_ATROPHIC_SCARS | HP_ATROPHIC_SCARS | HP_ATROPHIC_SCARS | 15/1438 | 36/23056 | 0.4166667 | 6.680575 | 8.797213 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/LAMB3/ITGA6/COL3A1/COL5A2/COL6A3/COL7A1/COL12A1/COL5A1/MMP1/C1S/C1R/COL1A1/ITGB4/COL6A2 | 15 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_KINASE_ACTIVITY | 58/1438 | 397/23056 | 0.1460957 | 2.342408 | 6.958469 | 0.0000000 | 0.0000000 | 0.0000000 | CCN1/CSF1/PTPRC/ATP2B4/TGFB2/AGT/TGFA/IL1B/EPHA4/TGFBR2/WNT5A/DOK7/EPGN/EREG/BTC/EGF/PDGFC/VEGFC/TLR3/HBEGF/ADRB2/FGF18/EDN1/TPD52L1/SASH1/PDGFA/ARHGEF5/TNFRSF10A/CLU/ADAM9/TCIM/ANGPT1/ADCY8/TNFSF15/FZD8/DKK1/FZD4/GPRC5A/NCKAP1L/HMGA2/IGF1/FLT3/FLT1/AJUBA/THBS1/LAT/CCL5/CCR7/GPRC5C/TNFRSF11A/ELANE/TGFB1/PRNP/BMP2/SDC4/CARD10/PDGFB/TENM1 | 58 |
| DELACROIX_RAR_TARGETS_UP | DELACROIX_RAR_TARGETS_UP | DELACROIX_RAR_TARGETS_UP | 17/1438 | 47/23056 | 0.3617021 | 5.799308 | 8.494404 | 0.0000000 | 0.0000000 | 0.0000000 | DHRS3/CRABP2/NID1/AOX1/BHLHE40/RARB/TM4SF1/FGF18/CCN2/TNFRSF11B/CA12/MSLN/TNFRSF12A/NUPR1/MMP2/CEBPB/SAT1 | 17 |
| KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | 17/1438 | 47/23056 | 0.3617021 | 5.799308 | 8.494404 | 0.0000000 | 0.0000000 | 0.0000000 | ERRFI1/CD53/LBH/IL1R1/RCAN2/THBS2/CAV2/CPED1/RBPMS/FBXO32/PTGS1/ANXA8L1/EPS8/HMGA2/DLX3/SMIM36/THBD | 17 |
| GOBP_SENSORY_SYSTEM_DEVELOPMENT | GOBP_SENSORY_SYSTEM_DEVELOPMENT | GOBP_SENSORY_SYSTEM_DEVELOPMENT | 57/1438 | 388/23056 | 0.1469072 | 2.355419 | 6.944439 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/RPE65/IGFN1/ATP2B4/TGFB2/WNT9A/EFEMP1/DLX1/DLX2/COL5A2/THRB/RARB/TGFBR2/LAMB2/WNT5A/MITF/COL8A1/FOXL2/KDR/SLC7A11/FOXC1/BMP6/TFAP2A/GJA1/CITED2/INHBA/GLI3/SEMA3A/TSPAN12/SHH/KLF4/CRB2/COL5A1/NRP1/PITX3/WT1/PLAAT3/CABP4/FZD4/CRYAB/FLT1/FREM2/BMP4/FBN1/ALDH1A2/ALDH1A3/SOX8/ADAMTS18/MAF/LHX1/SOX9/C3/SIX5/BFSP1/BIRC7/WNT7B/NDP | 57 |
| LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | LIN_SILENCED_BY_TUMOR_MICROENVIRONMENT | 26/1438 | 107/23056 | 0.2429907 | 3.895961 | 7.743852 | 0.0000000 | 0.0000000 | 0.0000000 | PTGS2/ELF3/CRIM1/ANXA3/INPP4B/SH3TC2/CCN2/SAMD9/PDK4/AIF1L/CLIC3/DKK1/PLAAT3/SYTL2/GPRC5A/EMP1/ARHGDIB/KRT7/KRT4/ALDH1A3/CLDN7/KRT13/SOX9/MUC16/KLK6/APOBEC3A | 26 |
| GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 18/1438 | 53/23056 | 0.3396226 | 5.445299 | 8.356048 | 0.0000000 | 0.0000000 | 0.0000000 | TGFB2/IL1B/TGFBR2/WWTR1/LEF1/DAB2/FOXC1/IL6/LOXL2/ZNF703/CRB2/NOTCH1/TCF7L2/BCL9L/BMP4/COL1A1/TGFB1/BMP2 | 18 |
| LANDIS_BREAST_CANCER_PROGRESSION_DN | LANDIS_BREAST_CANCER_PROGRESSION_DN | LANDIS_BREAST_CANCER_PROGRESSION_DN | 21/1438 | 72/23056 | 0.2916667 | 4.676402 | 8.058064 | 0.0000000 | 0.0000000 | 0.0000000 | CD34/COL3A1/COL6A3/CCDC80/FSTL1/PLAC8/TGFBI/GJA1/KLF4/COL5A1/NRP1/HTRA1/AHNAK/FZD4/VWF/IGFBP6/LUM/CRIP1/COL1A1/THBD/COL18A1 | 21 |
| WP_HIPPOMERLIN_SIGNALING_DYSREGULATION | WP_HIPPOMERLIN_SIGNALING_DYSREGULATION | WP_HIPPOMERLIN_SIGNALING_DYSREGULATION | 28/1438 | 123/23056 | 0.2276423 | 3.649875 | 7.599793 | 0.0000000 | 0.0000000 | 0.0000000 | EPHA2/ITGA10/ITGB6/ITGA6/ITGA4/ITGB5/FGFR3/KDR/CDH9/ITGA2/CCN2/ITGB8/MET/TEK/ITGA8/FGFR2/CD44/ITGA5/ITGA7/LATS2/FLT3/FLT1/AJUBA/ITGA11/CDH13/CDH15/ITGA3/ITGB4 | 28 |
| REACTOME_GPCR_LIGAND_BINDING | REACTOME_GPCR_LIGAND_BINDING | REACTOME_GPCR_LIGAND_BINDING | 64/1438 | 463/23056 | 0.1382289 | 2.216277 | 6.818523 | 0.0000000 | 0.0000000 | 0.0000000 | TAS1R1/ECE1/HTR1D/EDN2/PTCH2/S1PR1/WNT9A/AGT/SCTR/GPR39/ACKR3/HRH1/VIPR1/ACKR2/CCR3/UCN2/WNT5A/SUCNR1/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/F2RL1/CRHBP/ADRB2/EDN1/HCRTR2/FZD1/GPR37/SHH/PNOC/FZD6/ANXA1/S1PR3/FZD8/NPY4R/HTR7/CCKBR/ADM/SAA1/P2RY2/FZD4/C3AR1/WNT10B/HCAR1/EDNRB/BDKRB1/GPR132/GLP2R/CCL5/CCR7/GIP/GNGT2/C3/ADGRE1/S1PR5/C5AR1/FPR1/ADRA1D/WNT7B/CYSLTR1/LPAR4 | 64 |
| GAJATE_RESPONSE_TO_TRABECTEDIN_UP | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | 20/1438 | 66/23056 | 0.3030303 | 4.858600 | 8.096298 | 0.0000000 | 0.0000000 | 0.0000000 | TM4SF1/TGFBI/HLA-C/TNFAIP3/IL6/GPNMB/CLU/ANXA1/GSN/SRGN/CD44/CASP4/C1R/OASL/NID2/FOS/CRIP1/CYP19A1/NUPR1/CLDN7 | 20 |
| WESTON_VEGFA_TARGETS_3HR | WESTON_VEGFA_TARGETS_3HR | WESTON_VEGFA_TARGETS_3HR | 20/1438 | 66/23056 | 0.3030303 | 4.858600 | 8.096298 | 0.0000000 | 0.0000000 | 0.0000000 | TIE1/CD34/EFEMP1/KDR/SULT1E1/CXCL1/BMP6/AQP7/ANKRD1/MMP10/MMP1/NNMT/VWF/KRT7/FOXO1/BMP4/IL32/ADGRE1/SAT1/BGN | 20 |
| PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | 26/1438 | 108/23056 | 0.2407407 | 3.859888 | 7.683210 | 0.0000000 | 0.0000000 | 0.0000000 | LAMC2/FN1/PPARG/PLD1/ARSJ/ELL2/COL12A1/CADPS2/ASPH/MYBL1/NECAB1/AQP3/ANXA1/PHLDA2/MYEOV/EMP1/FREM2/CGNL1/ITPRIPL2/MT2A/MT1X/ABCC3/SLC16A3/B3GNT3/NCAM2/SAT1 | 26 |
| BROWNE_HCMV_INFECTION_14HR_DN | BROWNE_HCMV_INFECTION_14HR_DN | BROWNE_HCMV_INFECTION_14HR_DN | 47/1438 | 291/23056 | 0.1615120 | 2.589584 | 7.038017 | 0.0000000 | 0.0000000 | 0.0000000 | PRRX1/LAMC2/ACKR3/WNT5A/INPP4B/VEGFC/MYO10/ITGA2/HSPB3/CAP2/CRYBG1/SYNJ2/PDE1C/SERPINE1/MET/RBPMS/CEBPD/EXT1/HAS2/TPM2/GAS1/JCAD/DKK1/PLAU/ZCCHC24/PAPSS2/FAS/TCF7L2/MICAL2/MMP3/CASP1/NNMT/SLC10A2/ZFP36L1/AHNAK2/THBS1/ANXA2/SMAD6/PSMB10/CDH13/ITGA3/SLC14A2/BLVRB/AXL/RRAS/SIRPA/MAGEA10 | 47 |
| GOBP_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | GOBP_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | GOBP_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM | 44/1438 | 263/23056 | 0.1673004 | 2.682390 | 7.077147 | 0.0000000 | 0.0000001 | 0.0000000 | ECE1/HTR1D/EDN2/PTGS2/ATP2B4/AGT/CPS1/HRH1/SLIT2/SOD3/SLC4A4/ABCG2/NPR3/F2RL1/ADRB2/FOXC1/BMP6/EDN1/SOD2/SLC22A1/CD36/CAV1/ANGPT1/EXT1/TEK/SLC16A12/HTR7/ADM/PTPRJ/P2RY2/SLCO2B1/ARHGAP42/SLC6A13/KCNA5/EDNRB/MYLK3/MMP2/ABCC3/KLF2/PLVAP/TGFB1/APOE/ADRA1D/CYSLTR1 | 44 |
| WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | 37/1438 | 199/23056 | 0.1859296 | 2.981081 | 7.238912 | 0.0000000 | 0.0000001 | 0.0000000 | IFI16/TGFB2/EFEMP1/LONRF2/WNT5A/COL8A1/CCDC80/PLSCR4/SLIT2/KDR/PDGFC/C9/DAB2/CAP2/LAMA4/SOD2/GPNMB/GLI3/CAV1/FLNC/SULF1/ZFPM2/GAS1/PTGS1/MAP3K8/HTRA1/WT1/C1S/IGFBP6/ACSS3/AJUBA/MAF/SIRPA/PRNP/CRLS1/PROCR/DOK5 | 37 |
| GOBP_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 17/1438 | 48/23056 | 0.3541667 | 5.678489 | 8.368373 | 0.0000000 | 0.0000001 | 0.0000000 | CD34/OSR1/LAMB2/WWTR1/GDNF/PODXL/EXT1/NOTCH1/WT1/YAP1/EDNRB/BMP4/MYO1E/SALL1/LHX1/LIF/PDGFB | 17 |
| HP_ABNORMALITY_OF_BLADDER_MORPHOLOGY | HP_ABNORMALITY_OF_BLADDER_MORPHOLOGY | HP_ABNORMALITY_OF_BLADDER_MORPHOLOGY | 21/1438 | 73/23056 | 0.2876712 | 4.612342 | 7.972622 | 0.0000000 | 0.0000001 | 0.0000000 | LAMC2/LMOD1/LAMB3/ACTG2/ITGA6/COL3A1/COL5A2/MYLK/TMEM270/COL5A1/MYRF/EFEMP2/GRIP1/FREM2/FBLN5/FOXF1/MYOCD/COL1A1/ITGB4/MYL9/RAC2 | 21 |
| POOLA_INVASIVE_BREAST_CANCER_UP | POOLA_INVASIVE_BREAST_CANCER_UP | POOLA_INVASIVE_BREAST_CANCER_UP | 47/1438 | 292/23056 | 0.1609589 | 2.580715 | 7.010920 | 0.0000000 | 0.0000001 | 0.0000000 | GBP1/VCAM1/CD53/ECM1/CTSS/FCGR2A/PTPRC/HHIPL2/FAP/ITGA4/COL5A2/FN1/COL6A3/LRRC15/PLAC8/TDO2/DOCK2/PLA2G7/INHBA/SERPINE1/TPK1/SULF1/CCN4/EPPK1/TRAF1/COL5A1/SRGN/CREB3L1/MMP1/MMP3/CPM/GLIPR1/EPYC/SELPLG/SLC7A7/NID2/SERPINA6/LOXL1/BCL2A1/IL32/COTL1/HS3ST3A1/CCR7/SLC16A3/GDF15/LGALS2/KDELR3 | 47 |
| HOLLERN_EMT_BREAST_TUMOR_UP | HOLLERN_EMT_BREAST_TUMOR_UP | HOLLERN_EMT_BREAST_TUMOR_UP | 30/1438 | 140/23056 | 0.2142857 | 3.435724 | 7.455503 | 0.0000000 | 0.0000001 | 0.0000000 | HSPG2/CSF1/PRRX1/CFH/OSR1/AOX1/NRP2/FN1/TGFBR2/VEGFC/DAB2/FLNC/PLAT/MATN2/ZFPM2/TRAF1/ANKRD1/HHEX/EHBP1L1/EFEMP2/ITGA5/GLIPR1/LOXL1/RRAD/CDH13/MRC2/FXYD5/AXL/EMP3/CYSLTR1 | 30 |
| GOBP_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS | GOBP_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS | GOBP_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS | 24/1438 | 94/23056 | 0.2553191 | 4.093629 | 7.751425 | 0.0000000 | 0.0000001 | 0.0000000 | TBX15/PRRX1/OSR1/DLX2/TGFBR2/TFAP2A/MDFI/RUNX2/HOXA1/HOXA2/HOXA3/HOXA7/GLI3/FGFR2/ALX4/MMP14/BMP4/SIX1/SIX4/LHX1/HOXB2/HOXB3/HOXB7/NOG | 24 |
| GOBP_KIDNEY_MORPHOGENESIS | GOBP_KIDNEY_MORPHOGENESIS | GOBP_KIDNEY_MORPHOGENESIS | 24/1438 | 94/23056 | 0.2553191 | 4.093629 | 7.751425 | 0.0000000 | 0.0000001 | 0.0000000 | AGT/OSR1/WWTR1/HES1/NPNT/IRX2/ADAMTS16/GDNF/FOXD1/GLI3/SHH/WT1/BMP4/SIX1/SIX4/SOX8/SALL1/LHX1/HOXB7/NOG/SOX9/BMP2/LIF/WNT7B | 24 |
| GOBP_REGULATION_OF_OSSIFICATION | GOBP_REGULATION_OF_OSSIFICATION | GOBP_REGULATION_OF_OSSIFICATION | 27/1438 | 117/23056 | 0.2307692 | 3.700011 | 7.551364 | 0.0000000 | 0.0000001 | 0.0000000 | DHRS3/CCN1/S1PR1/CSF1/ECM1/TGFB2/OSR1/WNT5A/SGMS2/ADRB2/BMP6/TFAP2A/RUNX2/TENT5A/GJA1/FAM20C/PTN/NOTCH1/ALOX5/DKK1/SRGN/WNT10B/BMP4/SMAD6/SOX9/TGFB1/BMP2 | 27 |
| HP_ABNORMALITY_OF_SKIN_PHYSIOLOGY | HP_ABNORMALITY_OF_SKIN_PHYSIOLOGY | HP_ABNORMALITY_OF_SKIN_PHYSIOLOGY | 63/1438 | 456/23056 | 0.1381579 | 2.215138 | 6.759398 | 0.0000000 | 0.0000001 | 0.0000000 | TNFRSF1B/GFI1/PTPN22/ECM1/FCGR2A/LAMC2/PTPRC/LAMB3/NLRP3/ITGA6/CASP10/CASP8/SP110/IL17RC/COL7A1/SLCO2A1/ADAMTS3/SPP1/CFI/FAT4/VEGFC/IL7R/OSMR/IL31RA/STING1/RREB1/DSP/HLA-C/PSMB8/PSMB9/PLA2G7/GJA1/TNFAIP3/PERP/STX11/IL6/GPNMB/TEK/PTPN3/TNFSF15/GSN/MBL2/PAPSS2/FAS/NFKB2/FGFR2/LRRC32/MMP1/APOA1/TNFRSF1A/SCNN1A/NCKAP1L/EPB42/IL4R/PSMB10/KRT17/ITGB4/TMC8/ELANE/IL12RB1/TGFB1/RUNX1/MSN | 63 |
| CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP | 25/1438 | 102/23056 | 0.2450980 | 3.929750 | 7.648138 | 0.0000000 | 0.0000001 | 0.0000000 | CCN1/NID1/FNDC3B/BCL6/CCN2/PDK4/SERPINE1/FLNC/CLU/CEBPD/SYNPO2L/VCL/ANKRD1/POSTN/NFKBIA/MT2A/MT1X/MYOM1/FSTL3/GADD45B/CNN1/KLF2/ZFP36/CEBPB/CSDC2 | 25 |
| GOBP_MUSCLE_CELL_DEVELOPMENT | GOBP_MUSCLE_CELL_DEVELOPMENT | GOBP_MUSCLE_CELL_DEVELOPMENT | 35/1438 | 183/23056 | 0.1912568 | 3.066493 | 7.238561 | 0.0000000 | 0.0000001 | 0.0000000 | SYPL2/CASQ1/LMOD1/AGT/BMP10/DNER/HES1/MYOZ2/EDN1/TBX18/CAV2/LMOD2/FLNC/NOTCH1/MYPN/MYOZ1/SYNPO2L/ANKRD1/MYOF/ADM/EFEMP2/WNT10B/IGF1/NFATC4/BMP4/SIX1/SIX4/ACTC1/TPM1/ALPK3/MYLK3/KRT19/ALPK2/MYL9/NFATC2 | 35 |
| FARMER_BREAST_CANCER_CLUSTER_4 | FARMER_BREAST_CANCER_CLUSTER_4 | FARMER_BREAST_CANCER_CLUSTER_4 | 11/1438 | 19/23056 | 0.5789474 | 9.282483 | 9.314910 | 0.0000000 | 0.0000001 | 0.0000000 | FAP/COL3A1/COL5A2/SPARC/THBS2/COL5A1/HTRA1/NID2/DACT1/FBN1/SRPX2 | 11 |
| COWLING_MYCN_TARGETS | COWLING_MYCN_TARGETS | COWLING_MYCN_TARGETS | 16/1438 | 43/23056 | 0.3720930 | 5.965909 | 8.406217 | 0.0000000 | 0.0000001 | 0.0000000 | SYNC/LBH/SPP1/BMPER/SAMD9L/MMP10/MMP3/CRYAB/TAGLN/GALNT9/FBLN5/MFGE8/COPZ2/ALPK2/CNN1/MYL9 | 16 |
| GOBP_EAR_DEVELOPMENT | GOBP_EAR_DEVELOPMENT | GOBP_EAR_DEVELOPMENT | 39/1438 | 219/23056 | 0.1780822 | 2.855259 | 7.114779 | 0.0000000 | 0.0000001 | 0.0000000 | ECE1/PRRX1/TGFB2/OSR1/EPHA4/WNT5A/HES1/NKX3-2/TFAP2A/EDN1/DDR1/TBX18/PDGFA/HOXA1/HOXA2/BMPER/GLI3/SHH/FGF20/CEBPD/FZD6/CTHRC1/TMC1/NOTCH1/ITGA8/FGFR2/HMX3/FREM2/LRP10/BMP4/SIX1/SIX4/ESRRB/ALDH1A3/MAF/NOG/SOX9/BMP2/SDC4 | 39 |
| GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | 24/1438 | 95/23056 | 0.2526316 | 4.050538 | 7.684172 | 0.0000000 | 0.0000001 | 0.0000000 | LDLRAP1/S1PR1/PTGS2/AGT/TGFBR2/EREG/ITGA2/HBEGF/EDN1/GJA1/IL6/CCN4/FGFR2/IGF1/BMP4/THBS1/RBPMS2/MMP2/CDH13/CCL5/ELANE/TGFB1/HMOX1/PDGFB | 24 |
| HECKER_IFNB1_TARGETS | HECKER_IFNB1_TARGETS | HECKER_IFNB1_TARGETS | 24/1438 | 95/23056 | 0.2526316 | 4.050538 | 7.684172 | 0.0000000 | 0.0000001 | 0.0000000 | PDZK1IP1/IFI44L/GBP1/RTP4/SPON2/CXCL8/DDX60/TREML1/SAMD9/SAMD9L/PARP12/CLU/DDX58/MS4A4A/C3AR1/KLRD1/OASL/JUP/DHX58/IFI35/MYL9/MX2/MX1/APOBEC3A | 24 |
| DER_IFN_ALPHA_RESPONSE_UP | DER_IFN_ALPHA_RESPONSE_UP | DER_IFN_ALPHA_RESPONSE_UP | 21/1438 | 74/23056 | 0.2837838 | 4.550013 | 7.888713 | 0.0000000 | 0.0000001 | 0.0000000 | GBP1/RHOC/IFI16/NMI/CASP8/SP110/VEGFC/GMPR/HLA-E/HLA-C/PSMB8/PSMB9/IL6/FAS/C1S/OASL/IRF9/PSMB10/IFI35/MX2/MX1 | 21 |
| DASU_IL6_SIGNALING_UP | DASU_IL6_SIGNALING_UP | DASU_IL6_SIGNALING_UP | 19/1438 | 61/23056 | 0.3114754 | 4.994003 | 8.055841 | 0.0000000 | 0.0000001 | 0.0000000 | AGRN/TMEM158/CXCL8/CXCL3/IER3/TAPBP/SOD2/IL6/HTRA1/MMP1/MMP3/IRF9/ANPEP/SERPINB2/ZFP36/TGFB1/PLA2G4C/CEBPB/TFAP2C | 19 |
| GOBP_ORGAN_GROWTH | GOBP_ORGAN_GROWTH | GOBP_ORGAN_GROWTH | 34/1438 | 175/23056 | 0.1942857 | 3.115057 | 7.243655 | 0.0000000 | 0.0000001 | 0.0000000 | S1PR1/ECM1/TGFB2/AGT/BMP10/RARB/TGFBR2/HEG1/OSTN/FGFR3/FOXC1/EDN1/CITED2/SHH/FGF20/STC1/PLAG1/ZFPM2/RSPO2/EXT1/COL27A1/NOTCH1/FGFR2/WT1/YAP1/YBX3/GLI1/IGF1/LATS2/CYP19A1/NOG/SOX9/GATA6/RUNX1 | 34 |
| SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN | 34/1438 | 175/23056 | 0.1942857 | 3.115057 | 7.243655 | 0.0000000 | 0.0000001 | 0.0000000 | PDZK1IP1/CRABP2/DNER/TRPM8/AADAC/SULT1E1/SLC4A4/CXCL6/CXCL5/CD109/TPD52L1/PDK4/SLC26A4/MYBL1/HRCT1/COL27A1/FZD8/ANXA8/NNMT/SLC6A13/KRT7/KRT4/ACSS3/FREM2/SERPINA1/AHNAK2/CCDC9B/ANPEP/MSLN/ACSM3/RRAD/NQO1/ALPK2/CLIC6 | 34 |
| BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | 23/1438 | 88/23056 | 0.2613636 | 4.190542 | 7.733899 | 0.0000000 | 0.0000001 | 0.0000000 | EDN2/TGFB2/KYNU/EPHA4/PPARG/OSBPL10/SLC22A23/RNF144B/PTPRK/SASH1/TNS3/PDK4/EXT1/LRATD2/S1PR3/NRP1/TCF7L2/SYTL2/TNFRSF19/NPAS3/FRMD6/CDYL2/SLC16A5 | 23 |
| GOBP_PROSTATE_GLAND_DEVELOPMENT | GOBP_PROSTATE_GLAND_DEVELOPMENT | GOBP_PROSTATE_GLAND_DEVELOPMENT | 17/1438 | 49/23056 | 0.3469388 | 5.562601 | 8.245838 | 0.0000000 | 0.0000001 | 0.0000000 | WNT5A/ID4/GLI3/SHH/PLAG1/SULF1/ANXA1/NOTCH1/FGFR2/GLI1/BMP4/CRIP1/CYP19A1/MMP2/HOXB13/NOG/SOX9 | 17 |
| GOBP_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 27/1438 | 118/23056 | 0.2288136 | 3.668655 | 7.495660 | 0.0000000 | 0.0000001 | 0.0000000 | PTPRC/TGFA/IL1B/EPHA4/WNT5A/EPGN/EGF/PDGFC/FGF18/EDN1/TPD52L1/SASH1/PDGFA/ARHGEF5/ADAM9/FZD8/DKK1/FZD4/FLT3/FLT1/AJUBA/THBS1/TNFRSF11A/ELANE/TGFB1/PDGFB/TENM1 | 27 |
| PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_UP | 29/1438 | 134/23056 | 0.2164179 | 3.469911 | 7.395399 | 0.0000000 | 0.0000001 | 0.0000000 | S100A16/NID1/LBH/GXYLT2/FSTL1/PLSCR2/TGFBI/GMPR/COL12A1/BMPER/CAV2/TCIM/MATN2/GSN/TRIM5/CRYAB/APOA1/GLI1/HMGA2/TMCC3/NUAK1/LCP1/ZFP36L1/FBLN5/MMP2/ADGRE1/GMFG/EMP3/TGM2 | 29 |
| GOBP_MYELOID_LEUKOCYTE_DIFFERENTIATION | GOBP_MYELOID_LEUKOCYTE_DIFFERENTIATION | GOBP_MYELOID_LEUKOCYTE_DIFFERENTIATION | 38/1438 | 211/23056 | 0.1800948 | 2.887528 | 7.103842 | 0.0000000 | 0.0000001 | 0.0000000 | EPHA2/CSF1/IFI16/ITGB6/CASP8/PPARG/TGFBR2/MITF/LEF1/IL15/TLR3/IL31RA/F2RL1/CSF2/CD109/CITED2/FAM20C/ITGB8/HOXA7/INHBA/CCN4/UBASH3B/BMP4/ZFP36L1/FOS/FBN1/ANXA2/CSF3/CCR7/SIGLEC15/TNFRSF11A/FSTL3/TGFB1/RELB/CEBPB/RUNX1/LIF/MYH9 | 38 |
| WEINMANN_ADAPTATION_TO_HYPOXIA_DN | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | 15/1438 | 38/23056 | 0.3947368 | 6.328966 | 8.479206 | 0.0000000 | 0.0000001 | 0.0000000 | PLA2G4A/IL1A/COL3A1/VEGFC/IER3/TPBG/NT5E/SOD2/IL6/MEST/MMP1/NNMT/TPM1/SLC16A3/SDC4 | 15 |
| GOBP_EPIDERMIS_DEVELOPMENT | GOBP_EPIDERMIS_DEVELOPMENT | GOBP_EPIDERMIS_DEVELOPMENT | 51/1438 | 335/23056 | 0.1522388 | 2.440903 | 6.851688 | 0.0000000 | 0.0000001 | 0.0000000 | ERRFI1/EPHA2/PTCH2/TCHH/SPRR2F/CRABP2/LAMC2/LAMB3/TGFB2/CYP26B1/IL1A/COL7A1/WNT5A/HES1/EREG/FST/FOXC1/DSP/CD109/CCN2/PDGFA/HOXA7/INHBA/SHH/ADAM9/FZD6/EXT1/AQP3/TMC1/ANXA1/KLF4/NOTCH1/AKR1C3/DKK1/FGFR2/ALX4/PLAAT4/YAP1/EMP1/WNT10B/GLI1/TNFRSF19/BMP4/ZFP36L1/BNC1/KRT15/KRT17/HOXB13/SOX9/GATA6/ZFP36 | 51 |
| LI_CISPLATIN_RESISTANCE_DN | LI_CISPLATIN_RESISTANCE_DN | LI_CISPLATIN_RESISTANCE_DN | 14/1438 | 33/23056 | 0.4242424 | 6.802040 | 8.602229 | 0.0000000 | 0.0000001 | 0.0000001 | CFH/XIRP2/TDO2/PPIC/LAMA4/ADGRG6/MEST/IDO1/AKR1C3/FZD8/ADM/MMP10/AMIGO2/EDNRB | 14 |
| LIANG_SILENCED_BY_METHYLATION_UP | LIANG_SILENCED_BY_METHYLATION_UP | LIANG_SILENCED_BY_METHYLATION_UP | 14/1438 | 33/23056 | 0.4242424 | 6.802040 | 8.602229 | 0.0000000 | 0.0000001 | 0.0000001 | LAMC2/ANXA3/AQP1/PAPPA/ANXA8/SRGN/SAA1/MMP3/KRT7/KRT8/ALDH1A3/KRT19/KRT17/C3 | 14 |
| LIEN_BREAST_CARCINOMA_METAPLASTIC | LIEN_BREAST_CARCINOMA_METAPLASTIC | LIEN_BREAST_CARCINOMA_METAPLASTIC | 14/1438 | 33/23056 | 0.4242424 | 6.802040 | 8.602229 | 0.0000000 | 0.0000001 | 0.0000001 | PRRX1/KCNE4/IQCA1/EDIL3/SPARC/THBS2/PDGFA/HOXA7/RARRES2/LUM/POSTN/THBS1/ADAMTS5/COL18A1 | 14 |
| PLASARI_TGFB1_TARGETS_1HR_UP | PLASARI_TGFB1_TARGETS_1HR_UP | PLASARI_TGFB1_TARGETS_1HR_UP | 14/1438 | 33/23056 | 0.4242424 | 6.802040 | 8.602229 | 0.0000000 | 0.0000001 | 0.0000001 | SPSB1/PTGS2/NUAK2/WNT9A/BHLHE40/HES1/HBEGF/FGF18/ID4/IER3/IL6/SERPINE1/GADD45B/LIF | 14 |
| ROZANOV_MMP14_TARGETS_SUBSET | ROZANOV_MMP14_TARGETS_SUBSET | ROZANOV_MMP14_TARGETS_SUBSET | 14/1438 | 33/23056 | 0.4242424 | 6.802040 | 8.602229 | 0.0000000 | 0.0000001 | 0.0000001 | EFEMP1/FN1/LAMA4/MATN2/TNFRSF11B/HAS2/PTGS1/COL5A1/PAEP/ANKRD1/SERPINH1/EMILIN2/COL18A1/COL6A2 | 14 |
| WP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_PART_3_OF_3 | WP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_PART_3_OF_3 | WP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_PART_3_OF_3 | 23/1438 | 89/23056 | 0.2584270 | 4.143458 | 7.663104 | 0.0000000 | 0.0000001 | 0.0000001 | RUNX3/CD34/WNT5A/LEF1/FST/BMP6/CCN2/PERP/FZD1/GAS1/NOTCH1/DKK1/PHLDA1/IGF1/BMP4/FOS/KRT15/KRT19/DLX3/SOX9/ELANE/TGFB1/KLK6 | 23 |
| WP_SPINAL_CORD_INJURY | WP_SPINAL_CORD_INJURY | WP_SPINAL_CORD_INJURY | 27/1438 | 119/23056 | 0.2268908 | 3.637826 | 7.440558 | 0.0000000 | 0.0000001 | 0.0000001 | RHOC/FCGR2A/PTGS2/IL1R1/IL1A/IL1B/EPHA4/SLIT2/CXCL8/CXCL1/CXCL2/GDNF/ROS1/GJA1/IL6/AQP1/PTPRZ1/ANXA1/TNFSF13B/FOS/CSPG4/SOX9/MBP/ICAM1/MAG/ZFP36/TGFB1 | 27 |
| REACTOME_DISEASES_OF_GLYCOSYLATION | REACTOME_DISEASES_OF_GLYCOSYLATION | REACTOME_DISEASES_OF_GLYCOSYLATION | 30/1438 | 143/23056 | 0.2097902 | 3.363646 | 7.312464 | 0.0000000 | 0.0000001 | 0.0000001 | AGRN/HSPG2/ADAMTSL4/PRELP/GALNT3/MUC13/SPON2/ADAMTS3/ADAMTS16/SEMA5A/ADAMTS12/ADAMTS6/ADAMTS2/THBS2/EXT1/B4GALT1/NOTCH1/PAPSS2/ADAMTS8/ADAMTS15/LUM/THBS1/CSPG4/ADAMTS18/ADAMTSL5/MUC16/SDC4/ADAMTS5/GPC4/BGN | 30 |
| RUIZ_TNC_TARGETS_DN | RUIZ_TNC_TARGETS_DN | RUIZ_TNC_TARGETS_DN | 30/1438 | 143/23056 | 0.2097902 | 3.363646 | 7.312464 | 0.0000000 | 0.0000001 | 0.0000001 | CRIM1/EFEMP1/LYPD1/SERPINE2/TMEM158/P3H2/CXCL8/IL7R/FST/OGFRL1/CAV2/CAV1/MET/MEST/MYBL1/DKK1/PLAU/MYOF/MICAL2/CD44/FOSL1/GPRC5A/AMIGO2/NAV3/DIO2/THBS1/TPM1/TNFRSF12A/MT1X/SERPINB2 | 30 |
| FOROUTAN_PRODRANK_TGFB_EMT_DN | FOROUTAN_PRODRANK_TGFB_EMT_DN | FOROUTAN_PRODRANK_TGFB_EMT_DN | 22/1438 | 82/23056 | 0.2682927 | 4.301639 | 7.724536 | 0.0000000 | 0.0000001 | 0.0000001 | ELF3/CAVIN2/MITF/RBM47/EREG/SERPINB1/TFAP2A/TPD52L1/CITED2/PDK4/CEBPD/EHF/PLAAT4/PLAAT3/RAB38/BIRC3/SCNN1A/TNFAIP2/KRT19/GPRC5C/MBP/GDF15 | 22 |
| WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS | WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS | WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS | 19/1438 | 62/23056 | 0.3064516 | 4.913455 | 7.957986 | 0.0000000 | 0.0000001 | 0.0000001 | RUNX3/LTBP1/ITGB6/TGFBR2/SPP1/LEF1/EGF/FST/RUNX2/INHBA/SERPINE1/BMP4/FOS/THBS1/FBN1/SMAD6/NOG/TGFB1/LIF | 19 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINDED_IN_ERYTHROCYTE_UP | 16/1438 | 44/23056 | 0.3636364 | 5.830320 | 8.271405 | 0.0000000 | 0.0000001 | 0.0000001 | GBP2/ECM1/IFI16/TM4SF1/SLC7A11/CRHBP/DDR1/RBPMS/PLAT/TCF7L2/EMP1/AMIGO2/ALDH1A2/ANXA2/NQO1/GDF15 | 16 |
| WP_GENES_CONTROLLING_NEPHROGENESIS | WP_GENES_CONTROLLING_NEPHROGENESIS | WP_GENES_CONTROLLING_NEPHROGENESIS | 16/1438 | 44/23056 | 0.3636364 | 5.830320 | 8.271405 | 0.0000000 | 0.0000001 | 0.0000001 | LAMB2/SLIT2/KDR/GDNF/FOXD1/FOXC1/GLI3/CD36/SHH/ITGA8/FGFR2/WT1/SIX1/LHX1/ITGA3/PDGFB | 16 |
| KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 38/1438 | 213/23056 | 0.1784038 | 2.860415 | 7.035215 | 0.0000000 | 0.0000001 | 0.0000001 | ITGA10/ITGB6/ITGA6/ITGA4/FN1/MYLK/ITGB5/FGFR3/FGF5/EGF/PDGFC/ITGA2/IQGAP2/FGF18/PDGFA/SCIN/ITGB8/MYL7/FGF20/GSN/ITGA8/VCL/FGFR2/ITGA5/NCKAP1L/ITGA7/BDKRB1/ITGA11/MYLK3/ITGA3/ITGB4/RRAS/MYL9/MYH9/RAC2/PDGFB/MSN/ARHGEF6 | 38 |
| GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 37/1438 | 204/23056 | 0.1813725 | 2.908015 | 7.059745 | 0.0000000 | 0.0000001 | 0.0000001 | TGFB2/LTBP1/ITGB6/COL3A1/PPARG/TGFBR2/ITGB5/VEPH1/NPNT/DAB2/CD109/PTPRK/CITED2/ITGB8/CAV2/CAV1/ZYX/ZNF703/HTRA4/ADAM9/ITGA8/HTRA1/LRRC32/APOA1/BCL9L/LATS2/LTBP2/FOS/THBS1/FBN1/SMAD6/MYOCD/ITGA3/GDF15/TGFB1/PSG9/BMP2 | 37 |
| VERHAAK_AML_WITH_NPM1_MUTATED_DN | VERHAAK_AML_WITH_NPM1_MUTATED_DN | VERHAAK_AML_WITH_NPM1_MUTATED_DN | 42/1438 | 250/23056 | 0.1680000 | 2.693608 | 6.944045 | 0.0000000 | 0.0000001 | 0.0000001 | DHRS3/HSPG2/RUNX3/IFI44L/MTMR11/IFI16/GPA33/NIBAN1/CD34/GYPC/ITGA6/TFPI/SERPINE2/TMEM158/STK32B/ARAP2/NPR3/F2RL1/TGFBI/SPARC/GMPR/TNFRSF21/NT5E/GJA1/MDFIC/CAV1/MEST/CSGALNACT1/RBPMS/FZD6/GSN/ANXA8/EMP1/EPS8/FOXO1/MSLN/JUP/CAVIN1/ELANE/MX1/MN1/ITM2A | 42 |
| LANDIS_ERBB2_BREAST_TUMORS_324_DN | LANDIS_ERBB2_BREAST_TUMORS_324_DN | LANDIS_ERBB2_BREAST_TUMORS_324_DN | 31/1438 | 152/23056 | 0.2039474 | 3.269966 | 7.241685 | 0.0000000 | 0.0000001 | 0.0000001 | CD34/COL3A1/CAVIN2/COL6A3/CCDC80/FSTL1/JCHAIN/PLAC8/TGFBI/GJA1/CD36/ZNF703/KLF4/COL5A1/NRP1/PAPSS2/HTRA1/AHNAK/FZD4/MMP3/VWF/IGFBP6/LUM/POSTN/CRIP1/CES1/KRT19/COL1A1/THBD/MYL9/COL18A1 | 31 |
| GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | 17/1438 | 50/23056 | 0.3400000 | 5.451349 | 8.126627 | 0.0000000 | 0.0000001 | 0.0000001 | TNFRSF1B/TIE1/AGT/DPP4/FAP/PHLDB2/ADTRP/DDR1/IL6/HAS2/NOTCH1/EFEMP2/TNFRSF1A/SOX9/TGFB1/BMP2/RUNX1 | 17 |
| WESTON_VEGFA_TARGETS_6HR | WESTON_VEGFA_TARGETS_6HR | WESTON_VEGFA_TARGETS_6HR | 17/1438 | 50/23056 | 0.3400000 | 5.451349 | 8.126627 | 0.0000000 | 0.0000001 | 0.0000001 | FAP/COL6A3/SULT1E1/SEMA5A/MEST/AQP7/ANKRD1/NNMT/C1S/KRT18/POSTN/NID2/BMP4/MMP2/SDC4/SAT1/BGN | 17 |
| ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | 30/1438 | 144/23056 | 0.2083333 | 3.340287 | 7.265629 | 0.0000000 | 0.0000001 | 0.0000001 | GBP2/GBP4/VCAM1/CD53/CTSS/S100A11/PTPRC/NABP1/SHISA5/CXCL2/PLAC8/HLA-E/PSMB9/TAPBP/MSR1/APBB1IP/CYP26A1/MS4A4A/CASP1/NNMT/SELPLG/BCL2A1/MT1X/CD68/CCL5/ADGRE1/RRAS/FPR1/SIRPA/PROCR | 30 |
| GOBP_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | GOBP_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | GOBP_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 34/1438 | 178/23056 | 0.1910112 | 3.062556 | 7.124607 | 0.0000000 | 0.0000001 | 0.0000001 | GFI1/CSF1/ECM1/PTPRC/IKBKE/IL1R1/CASP8/IRAK2/PPARG/WNT5A/PARP14/SLIT2/TXK/F2RL1/TSLP/STING1/EDN1/TNFAIP3/IL6/TRIM56/CAV1/ANGPT1/DDX58/KLF4/CASP4/CASP1/CARD16/APOA1/TNFRSF1A/NLRC5/CCL5/AXL/BIRC7/USP18 | 34 |
| GOCC_CAVEOLA | GOCC_CAVEOLA | GOCC_CAVEOLA | 22/1438 | 83/23056 | 0.2650602 | 4.249811 | 7.649668 | 0.0000000 | 0.0000001 | 0.0000001 | PTGS2/ATP2B4/TFPI/CAVIN2/TGFBR2/GASK1A/ADTRP/CD36/CAV2/CAV1/ADCY8/MYOF/KCNA5/TRPC4/CDH13/CDH15/CAVIN1/PLVAP/EHD2/PTGIS/HMOX1/MLC1 | 22 |
| REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS | REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS | REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS | 15/1438 | 39/23056 | 0.3846154 | 6.166684 | 8.328641 | 0.0000000 | 0.0000001 | 0.0000001 | ADAMTSL4/SPON2/ADAMTS3/ADAMTS16/SEMA5A/ADAMTS12/ADAMTS6/ADAMTS2/THBS2/ADAMTS8/ADAMTS15/THBS1/ADAMTS18/ADAMTSL5/ADAMTS5 | 15 |
| LEE_LIVER_CANCER_E2F1_UP | LEE_LIVER_CANCER_E2F1_UP | LEE_LIVER_CANCER_E2F1_UP | 19/1438 | 63/23056 | 0.3015873 | 4.835464 | 7.862209 | 0.0000000 | 0.0000001 | 0.0000001 | CTSS/FMO3/ACTG2/COL5A2/SPON2/SPARC/CYP39A1/NT5E/PLAT/FABP4/ANXA1/JCAD/CASP4/KRT8/ANXA2/BCL2A1/MFGE8/COL1A1/USP18 | 19 |
| MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | MCBRYAN_PUBERTAL_TGFB1_TARGETS_DN | 19/1438 | 63/23056 | 0.3015873 | 4.835464 | 7.862209 | 0.0000000 | 0.0000001 | 0.0000001 | NID1/BCL6/JCHAIN/ID4/SOD2/PDK4/PTN/SFTPD/PPP1R3C/NFKB2/ADM/VWF/PHLDA1/NID2/TNFAIP2/MT1X/ABCC3/BCL3/PTGIS | 19 |
| GOCC_BASAL_PART_OF_CELL | GOCC_BASAL_PART_OF_CELL | GOCC_BASAL_PART_OF_CELL | 44/1438 | 271/23056 | 0.1623616 | 2.603206 | 6.847051 | 0.0000000 | 0.0000001 | 0.0000001 | LDLRAP1/ADCY10/ATP2B4/CD34/TGFA/FAP/PHLDB2/CLDN1/SLC4A4/NKD2/ITGA2/DSP/EDN1/HFE/SLC22A1/AQP1/MET/SLC26A7/ADCY8/EPPK1/TEK/B4GALT1/AQP7/AQP3/ANXA1/SLC16A12/CD44/SLC6A13/TRPC4/SLC7A7/ANXA2/CLDN7/SLC47A1/ITGA3/ABCC3/ABCA8/ITGB4/SLC16A3/SLC14A1/ALPK2/C5AR1/PDGFB/MLC1/MSN | 44 |
| WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | 27/1438 | 121/23056 | 0.2231405 | 3.577696 | 7.332116 | 0.0000000 | 0.0000001 | 0.0000001 | TNFRSF1B/ECE1/GBP3/MTMR11/CD34/GALNT3/COL3A1/COL5A2/FN1/COL6A3/PARP14/JCHAIN/SPARC/TNFAIP3/SERPINE1/SRGN/TCF7L2/IFITM3/C1S/C1R/LUM/TNFRSF12A/CCR7/PECAM1/SOCS3/SDC4/LGALS2 | 27 |
| MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | 28/1438 | 129/23056 | 0.2170543 | 3.480113 | 7.285293 | 0.0000000 | 0.0000001 | 0.0000001 | GBP2/C1orf54/ECM1/MR1/RAB7B/IKBKE/ACTG2/CAPG/COL3A1/IL17RC/BTC/DDR1/GPSM3/INHBA/CCN4/ANXA1/CASP4/NNMT/VWA5A/ARHGDIB/TNS2/SOAT2/LUM/POSTN/OSGIN1/IFI35/SERPINB8/EMP3 | 28 |
| GOBP_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | GOBP_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | GOBP_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 65/1438 | 487/23056 | 0.1334702 | 2.139979 | 6.557818 | 0.0000000 | 0.0000001 | 0.0000001 | ECE1/HTR1D/EDN2/CRABP2/PTGS2/LMOD1/AGT/CAPG/SCTR/CPS1/FN1/HRH1/SEMA3B/WNT5A/SLC12A8/SLIT2/SOD3/SPP1/SLC12A7/SEMA5A/NPR3/IL7R/F2RL1/ADRB2/FOXC1/EDN1/ARHGAP18/SOD2/SCIN/AQP1/CCL26/SEMA3C/SEMA3A/SEMA3D/CAV1/LMOD2/EXT1/GSN/NRP1/HTR7/ADM/P2RY2/ARHGAP42/KCNA5/EPS8/NCKAP1L/EDNRB/MMP2/COTL1/TRPV2/CSF3/CCR7/SEMA6B/PEX11G/KLF2/MAG/KCNN4/APOE/CDC42EP5/ADRA1D/CDC42EP1/WNT7B/MSN/CYSLTR1/TENM1 | 65 |
| GOBP_ENDOCHONDRAL_BONE_MORPHOGENESIS | GOBP_ENDOCHONDRAL_BONE_MORPHOGENESIS | GOBP_ENDOCHONDRAL_BONE_MORPHOGENESIS | 18/1438 | 57/23056 | 0.3157895 | 5.063173 | 7.921410 | 0.0000000 | 0.0000001 | 0.0000001 | COL3A1/RARB/TGFBR2/FGFR3/FGF18/FOXC1/BMP6/RUNX2/CSGALNACT1/STC1/EXT1/COL27A1/COL13A1/SERPINH1/MMP14/BMP4/COL1A1/SOX9 | 18 |
| GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 56/1438 | 392/23056 | 0.1428571 | 2.290483 | 6.646320 | 0.0000000 | 0.0000001 | 0.0000001 | S1PR1/RHOC/S100A10/LMOD1/BMP10/CAPG/IL1A/TNNC1/EPHA3/PHLDB2/SLIT2/SEMA5A/IQGAP2/F2RL1/DSP/EDN1/ARHGAP18/CCN2/PDGFA/SCIN/CCL26/CAV1/MET/LMOD2/ARHGEF5/STC1/TEK/GSN/NRP1/SYNPO2L/APOA1/ARHGDIB/EPS8/RND1/NCKAP1L/FRMD6/CGNL1/TPM1/HCN4/MYLK3/COTL1/CSF3/CCR7/JUP/KCNJ2/DSG2/SIGLEC15/CNN2/GMFG/CDC42EP5/SDC4/MYH9/RAC2/CDC42EP1/CELSR1/TENM1 | 56 |
| BROWNE_HCMV_INFECTION_16HR_DN | BROWNE_HCMV_INFECTION_16HR_DN | BROWNE_HCMV_INFECTION_16HR_DN | 22/1438 | 84/23056 | 0.2619048 | 4.199218 | 7.575972 | 0.0000000 | 0.0000001 | 0.0000001 | DHRS3/ATP2B4/CAMK1G/WNT5A/SLIT2/SEMA5A/ADAMTS2/GJA1/SEMA3A/RBPMS/AKR1C3/NRP1/COL13A1/ANKRD1/SERPINH1/THBS1/TPM1/ANPEP/COL1A1/SLC16A5/RUNX1/NDP | 22 |
| GOBP_RENAL_SYSTEM_PROCESS | GOBP_RENAL_SYSTEM_PROCESS | GOBP_RENAL_SYSTEM_PROCESS | 26/1438 | 114/23056 | 0.2280702 | 3.656736 | 7.333975 | 0.0000000 | 0.0000001 | 0.0000001 | CD34/AGT/SUCNR1/JCHAIN/ABCG2/NPR3/F2RL1/EDN1/ADGRF5/AQP1/PON3/STC1/SULF1/HAS2/AQP3/PCSK5/GSN/AKR1C3/ADM/SPX/EDNRB/BMP4/MYO1E/ITGA3/PDGFB/TBC1D8B | 26 |
| GOMF_METALLOENDOPEPTIDASE_ACTIVITY | GOMF_METALLOENDOPEPTIDASE_ACTIVITY | GOMF_METALLOENDOPEPTIDASE_ACTIVITY | 26/1438 | 114/23056 | 0.2280702 | 3.656736 | 7.333975 | 0.0000000 | 0.0000001 | 0.0000001 | MMP23B/ECE1/TRABD2B/TRABD2A/MME/ADAMTS3/ADAMTS16/ADAMTS12/ADAMTS6/ADAM19/ADAMTS2/ADAM28/ADAM9/ADAM32/PAPPA/TLL2/MMP10/MMP1/MMP3/ADAMTS8/ADAMTS15/MMP14/MMP2/ADAMTS18/ADAM33/ADAMTS5 | 26 |
| ELVIDGE_HYPOXIA_UP | ELVIDGE_HYPOXIA_UP | ELVIDGE_HYPOXIA_UP | 33/1438 | 172/23056 | 0.1918605 | 3.076172 | 7.048809 | 0.0000000 | 0.0000001 | 0.0000001 | ECE1/CCN1/S100A2/ELF3/BHLHE40/PLAC8/VEGFC/TGFBI/DDR1/GJA1/CITED2/SERPINE1/CAV1/MET/PDGFRL/CSGALNACT1/LOXL2/STC1/ASPH/ADM/GPRC5A/KRT7/FOS/AHNAK2/LOXL1/ORAI3/KRT15/CAVIN1/SOX9/GADD45B/GDF15/PDGFB/SAT1 | 33 |
| GOBP_POSITIVE_CHEMOTAXIS | GOBP_POSITIVE_CHEMOTAXIS | GOBP_POSITIVE_CHEMOTAXIS | 19/1438 | 64/23056 | 0.2968750 | 4.759910 | 7.768430 | 0.0000000 | 0.0000002 | 0.0000001 | S1PR1/WNT5A/KDR/CXCL8/VEGFC/SEMA5A/GDNF/ITGA2/F2RL1/GPNMB/MET/ANGPT1/COLEC10/NRP1/PTPRJ/BMP4/CDH13/CCL5/PDGFB | 19 |
| GOBP_METANEPHRIC_NEPHRON_DEVELOPMENT | GOBP_METANEPHRIC_NEPHRON_DEVELOPMENT | GOBP_METANEPHRIC_NEPHRON_DEVELOPMENT | 15/1438 | 40/23056 | 0.3750000 | 6.012517 | 8.183239 | 0.0000000 | 0.0000002 | 0.0000001 | CD34/OSR1/LAMB2/HES1/IRX2/GDNF/FOXD1/WT1/BMP4/SOX8/SALL1/LHX1/SOX9/LIF/PDGFB | 15 |
| TRAYNOR_RETT_SYNDROM_UP | TRAYNOR_RETT_SYNDROM_UP | TRAYNOR_RETT_SYNDROM_UP | 15/1438 | 40/23056 | 0.3750000 | 6.012517 | 8.183239 | 0.0000000 | 0.0000002 | 0.0000001 | PLA2G4A/LTBP1/DPP4/GALNT15/SPON2/HSPB3/MOXD1/IL6/SYTL2/MMP10/MMP1/MMP3/C1R/TNFRSF19/CA12 | 15 |
| GOBP_CARDIAC_SEPTUM_MORPHOGENESIS | GOBP_CARDIAC_SEPTUM_MORPHOGENESIS | GOBP_CARDIAC_SEPTUM_MORPHOGENESIS | 20/1438 | 71/23056 | 0.2816901 | 4.516445 | 7.653587 | 0.0000000 | 0.0000002 | 0.0000001 | DHRS3/CCN1/TGFB2/NRP2/TGFBR2/WNT5A/HES1/FGFRL1/SLIT2/CITED2/SEMA3C/FZD1/ZFPM2/NOTCH1/NRP1/FGFR2/BMP4/SMAD6/NOG/GATA6 | 20 |
| BURTON_ADIPOGENESIS_9 | BURTON_ADIPOGENESIS_9 | BURTON_ADIPOGENESIS_9 | 22/1438 | 85/23056 | 0.2588235 | 4.149816 | 7.503414 | 0.0000000 | 0.0000002 | 0.0000001 | CCN1/VCAM1/CSF1/PTGS2/PLA2G4A/RASSF5/CXCL2/SPP1/PLK2/TPD52L1/CITED2/THBS2/SKAP2/PLAT/CEBPD/KLF4/PHLDA1/LATS2/FOS/TPM1/JUP/GPC4 | 22 |
| WP_TGFBETA_RECEPTOR_SIGNALING | WP_TGFBETA_RECEPTOR_SIGNALING | WP_TGFBETA_RECEPTOR_SIGNALING | 18/1438 | 58/23056 | 0.3103448 | 4.975877 | 7.819088 | 0.0000000 | 0.0000002 | 0.0000001 | RUNX3/LTBP1/ITGB6/TGFBR2/SPP1/LEF1/EGF/FST/RUNX2/INHBA/SERPINE1/BMP4/FOS/THBS1/SMAD6/NOG/TGFB1/LIF | 18 |
| HALLMARK_HYPOXIA | HALLMARK_HYPOXIA | HALLMARK_HYPOXIA | 36/1438 | 200/23056 | 0.1800000 | 2.886008 | 6.908961 | 0.0000000 | 0.0000002 | 0.0000001 | ERRFI1/EDN2/CCN1/ACKR3/BHLHE40/PLAC8/TGFBI/IER3/TPBG/CCN2/TNFAIP3/CITED2/IL6/SERPINE1/CAV1/STC1/EXT1/COL5A1/PPP1R3C/ADM/PYGM/FOS/ANXA2/CA12/MT2A/CAVIN1/ZFP36/HAS1/TGM2/SDC4/HMOX1/MYH9/KDELR3/PDGFB/GPC4/BGN | 36 |
| PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | 16/1438 | 46/23056 | 0.3478261 | 5.576828 | 8.013817 | 0.0000000 | 0.0000002 | 0.0000001 | ERRFI1/EPHA2/BHLHE40/EREG/SLC7A11/ITGA2/HBEGF/RUNX2/TNFRSF21/CCN2/ADGRG6/FOSL1/MPZL2/PHLDA1/PLEK2/LIF | 16 |
| STEGER_ADIPOGENESIS_DN | STEGER_ADIPOGENESIS_DN | STEGER_ADIPOGENESIS_DN | 12/1438 | 25/23056 | 0.4800000 | 7.696022 | 8.639423 | 0.0000000 | 0.0000002 | 0.0000001 | OLFML3/OSR1/WNT5A/FSTL1/PLA2G7/THBS2/PDLIM2/PLAT/CCN4/CD44/POSTN/MMP2 | 12 |
| GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION | 53/1438 | 365/23056 | 0.1452055 | 2.328135 | 6.596536 | 0.0000000 | 0.0000002 | 0.0000001 | ERRFI1/EPHA2/ZC3H12A/GBP1/PTPN22/PTPRC/CD34/TGFB2/NLRP3/NMI/FN1/CD96/BCL6/LEF1/F2RL1/SERPINB1/HFE/TNFRSF21/TNFAIP3/IL6/GPNMB/INHBA/IDO1/ANGPT1/CD274/PDCD1LG2/ANXA1/KLF4/SRGN/SFTPD/NLRP6/LRRC32/CARD16/APOA1/NCKAP1L/NAV3/IGF1/THBS1/CCR7/DHX58/GATA6/ELANE/IL27RA/KLF2/ZFP36/AXL/TGFB1/PSG9/BCL3/RELB/SIRPA/PRNP/HMOX1 | 53 |
| GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | GOBP_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 52/1438 | 355/23056 | 0.1464789 | 2.348551 | 6.604097 | 0.0000000 | 0.0000002 | 0.0000001 | TNFRSF4/TNFRSF1B/ZC3H12A/PTPN22/MR1/CFH/PTPRC/TGFB2/NLRP3/IL1R1/IL1B/WNT5A/CD96/BCL6/SPON2/CXCL6/DDX60/TLR3/IL7R/F2RL1/MZB1/HFE/HLA-E/MICA/RAET1E/AHR/IL6/CD36/ANGPT1/COLEC10/DDX58/ANXA1/MBL2/PTPRJ/APOA1/KLRD1/KLRC4-KLRK1/NCKAP1L/STAT6/IL4R/FOXF1/DHX58/C3/ICAM1/IL27RA/IL12RB1/CD22/TGFB1/NECTIN2/IL4I1/HMOX1/RAC2 | 52 |
| LI_INDUCED_T_TO_NATURAL_KILLER_UP | LI_INDUCED_T_TO_NATURAL_KILLER_UP | LI_INDUCED_T_TO_NATURAL_KILLER_UP | 48/1438 | 315/23056 | 0.1523810 | 2.443182 | 6.651594 | 0.0000000 | 0.0000002 | 0.0000001 | TNFRSF18/TNFRSF9/ERRFI1/GBP2/S100A10/S100A11/S100A13/FCGR2A/HSD11B1/CAPG/SERPINE2/BHLHE40/IRAK2/TMEM158/SPP1/IQGAP2/IER3/TENT5A/NT5E/CRYBG1/CCN2/STX11/PDGFA/SCIN/SAMD9L/DOK2/TNFRSF11B/TRPM6/TRAF1/HHEX/BAG3/IFITM2/IFITM3/AHNAK/SYTL2/CASP1/KLRD1/EMP1/GLIPR1/EHD4/MYO1E/ANXA2/MLKL/COTL1/CCL5/EMILIN2/FXYD5/LGALS1 | 48 |
| GOMF_ENDOPEPTIDASE_ACTIVITY | GOMF_ENDOPEPTIDASE_ACTIVITY | GOMF_ENDOPEPTIDASE_ACTIVITY | 60/1438 | 439/23056 | 0.1366743 | 2.191350 | 6.499927 | 0.0000000 | 0.0000002 | 0.0000001 | MMP23B/ECE1/TRABD2B/CTSS/TRABD2A/DPP4/FAP/CASP10/CASP8/CPS1/MME/ADAMTS3/CFI/CTSO/ADAMTS16/ADAMTS12/ADAMTS6/PCSK1/ERAP2/ADAM19/ADAMTS2/PSMB8/PSMB9/ADGRG6/SHH/ADAM28/HTRA4/ADAM9/ADAM32/PLAT/PCSK5/PAPPA/PLAU/TLL2/HTRA1/NRIP3/PRSS23/MMP10/MMP1/MMP3/CASP4/CASP1/ADAMTS8/ADAMTS15/C1S/C1R/C1RL/MMP14/RHBDF1/MMP2/PSMB10/CTRB1/ADAMTS18/RHBDF2/ELANE/KLK6/ADAM33/ADAMTS5/BACE2/USP18 | 60 |
| GOBP_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | GOBP_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | GOBP_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | 19/1438 | 65/23056 | 0.2923077 | 4.686680 | 7.676575 | 0.0000000 | 0.0000002 | 0.0000001 | AGT/WNT5A/EGF/ADAMTS12/GDNF/GJA1/PDGFA/SHH/SULF1/MMRN2/BMP4/SIX1/SIX4/SOX8/LHX1/HOXB7/NOG/SOX9/LIF | 19 |
| GOBP_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT | GOBP_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT | GOBP_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT | 13/1438 | 30/23056 | 0.4333333 | 6.947798 | 8.407402 | 0.0000000 | 0.0000002 | 0.0000001 | CD34/OSR1/HES1/PDGFA/ANGPT1/TEK/NOTCH1/NRP1/WT1/BMP4/PECAM1/SERPINB7/PDGFB | 13 |
| HP_ABNORMALITY_OF_HUMORAL_IMMUNITY | HP_ABNORMALITY_OF_HUMORAL_IMMUNITY | HP_ABNORMALITY_OF_HUMORAL_IMMUNITY | 44/1438 | 276/23056 | 0.1594203 | 2.556046 | 6.707403 | 0.0000000 | 0.0000002 | 0.0000001 | TNFRSF1B/CFH/CASP10/CASP8/SP110/COL7A1/ADAMTS3/SPP1/CFI/FAT4/IL7R/C9/STING1/HFE/PSMB8/PSMB9/PLA2G7/STX11/SAMD9L/TNFSF15/FAS/NFKB2/C1S/NCKAP1L/SLC7A7/SERPINA1/IL4R/IL21R/LAT/CAVIN1/COL1A1/TNFRSF11A/ELANE/CD70/C3/PLVAP/IL12RB1/TGFB1/KCNN4/HMOX1/IL2RB/RAC2/MSN/GPC4 | 44 |
| MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 37/1438 | 210/23056 | 0.1761905 | 2.824929 | 6.851801 | 0.0000000 | 0.0000002 | 0.0000001 | PODN/RASSF5/WNT9A/CCDC85A/FGF5/GPAT3/CDS1/GDNF/CCNO/PRDM6/ADAMTS2/TFAP2A/PSMB9/SLC26A4/SHH/PLAG1/RSPO2/COL27A1/AHNAK/ADAMTS8/KCNH3/FLT1/RAB20/ESRRB/SLC24A4/BMF/FOXB1/SMAD6/FOXF1/HS3ST3A1/ITGA3/NOG/GPRC5C/GATA6/TGFB1/KDELR3/A4GALT | 37 |
| GOBP_MESODERM_DEVELOPMENT | GOBP_MESODERM_DEVELOPMENT | GOBP_MESODERM_DEVELOPMENT | 28/1438 | 132/23056 | 0.2121212 | 3.401020 | 7.134964 | 0.0000000 | 0.0000002 | 0.0000001 | EPHA2/TIE1/OSR1/WNT5A/LEF1/ITGA2/FOXC1/GJA1/CITED2/INHBA/MEST/SHH/ZFPM2/EXT1/KLF4/CRB2/ITGA8/DKK1/FGFR2/YAP1/HMGA2/BMP4/ZFP36L1/FOXF1/LHX1/ITGA3/NOG/ITGB4 | 28 |
| GOBP_RESPONSE_TO_CORTICOSTEROID | GOBP_RESPONSE_TO_CORTICOSTEROID | GOBP_RESPONSE_TO_CORTICOSTEROID | 31/1438 | 157/23056 | 0.1974522 | 3.165827 | 7.022949 | 0.0000000 | 0.0000002 | 0.0000001 | ERRFI1/TRIM63/PTGS2/CPS1/CLDN1/SLIT2/ANXA3/PCSK1/SOX30/BMP6/EDN1/CCN2/IL6/AQP1/STC1/ADAM9/PLAT/FBXO32/ANXA1/PAPPA/NOTCH1/AKR1C3/ADM/FIBIN/FOSL1/FLT3/ZFP36L1/FOS/COL1A1/ZFP36/WNT7B | 31 |
| GOBP_POSITIVE_REGULATION_OF_CELL_ACTIVATION | GOBP_POSITIVE_REGULATION_OF_CELL_ACTIVATION | GOBP_POSITIVE_REGULATION_OF_CELL_ACTIVATION | 59/1438 | 429/23056 | 0.1375291 | 2.205057 | 6.497959 | 0.0000000 | 0.0000002 | 0.0000001 | TNFRSF4/RUNX3/VCAM1/PTPN22/PLA2G4A/PTPRC/ITPKB/NLRP3/IL1A/IL1B/DPP4/TGFBR2/WNT5A/BCL6/HES1/LEF1/IL15/IL7R/F2RL1/TSLP/HLA-E/CCN2/VNN1/IL6/GLI3/CAV1/SHH/CD274/PDCD1LG2/ANXA1/IL15RA/MAP3K8/KLRC4-KLRK1/NCKAP1L/TESPA1/STAT6/IGF1/TNFSF13B/MMP14/THBS1/IL4R/CCL5/CCR7/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/AXL/TGFB1/NECTIN2/IL4I1/SIRPG/SIRPA/NFATC2/RUNX1/ICOSLG/LGALS1 | 59 |
| GOBP_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 33/1438 | 175/23056 | 0.1885714 | 3.023437 | 6.929877 | 0.0000000 | 0.0000002 | 0.0000001 | TRABD2B/TRABD2A/WNT5A/WWTR1/NKD2/DAB2/SOX30/MDFI/TPBG/TBX18/GLI3/HECW1/FZD1/CAV1/SHH/FZD6/CTHRC1/NOTCH1/DKK1/TCF7L2/FZD4/IGFBP6/GLI1/LATS2/FOXO1/NFATC4/DACT1/NOG/SOX9/ALPK2/APOE/BMP2/APCDD1L | 33 |
| REACTOME_MET_PROMOTES_CELL_MOTILITY | REACTOME_MET_PROMOTES_CELL_MOTILITY | REACTOME_MET_PROMOTES_CELL_MOTILITY | 15/1438 | 41/23056 | 0.3658537 | 5.865871 | 8.042689 | 0.0000000 | 0.0000002 | 0.0000002 | LAMC2/LAMB3/COL3A1/COL5A2/FN1/LAMB2/ITGA2/LAMA4/LAMA2/TNS3/MET/COL27A1/COL5A1/ITGA3/COL1A1 | 15 |
| MATTHEWS_AP1_TARGETS | MATTHEWS_AP1_TARGETS | MATTHEWS_AP1_TARGETS | 10/1438 | 17/23056 | 0.5882353 | 9.431400 | 8.969053 | 0.0000000 | 0.0000002 | 0.0000002 | PTGS2/LBH/SPP1/HBEGF/CAV1/FLNC/CA3/CD44/MMP10/BCL3 | 10 |
| PID_INTEGRIN5_PATHWAY | PID_INTEGRIN5_PATHWAY | PID_INTEGRIN5_PATHWAY | 10/1438 | 17/23056 | 0.5882353 | 9.431400 | 8.969053 | 0.0000000 | 0.0000002 | 0.0000002 | CCN1/VCAM1/ITGB6/ITGA4/FN1/ITGB5/EDIL3/ITGB8/PLAU/FBN1 | 10 |
| GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 38/1438 | 221/23056 | 0.1719457 | 2.756871 | 6.768457 | 0.0000000 | 0.0000003 | 0.0000002 | TNFRSF1B/PTPRC/TGFB2/AGT/IL1A/IL1B/ITGA6/CASP8/SP100/FGFR3/TLR3/GDNF/CSF2/TNFAIP3/INHBA/SERPINE1/CAV1/TNFRSF10C/TNFRSF10A/TRAF1/NRP1/FAS/ITPRIP/TCF7L2/BAG3/YAP1/TNFRSF1A/KRT18/IGF1/BMP4/THBS1/BCL2A1/TNFRSF12A/TMC8/CD70/ICAM1/TGFB1/HMOX1 | 38 |
| GOBP_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | GOBP_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | GOBP_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 45/1438 | 288/23056 | 0.1562500 | 2.505216 | 6.629591 | 0.0000000 | 0.0000003 | 0.0000002 | ZC3H12A/RHOC/ECM1/S100A13/IKBKE/IL1A/IL1B/CASP10/CASP8/IRAK2/SHISA5/WNT5A/TNIP3/TLR3/TRIML2/TRIML1/PLK2/F2RL1/EDN1/TRIM38/GJA1/TNFAIP3/CD36/ANGPT1/TRAF1/NEK6/NLRP6/TRIM5/BIRC3/CASP1/CARD16/TNFRSF1A/TNFRSF19/EDNRB/AJUBA/PRKD1/NFKBIA/CCR7/BCL3/RELB/SIRPA/DEFB124/HMOX1/APOL3/LGALS1 | 45 |
| GOBP_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | GOBP_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | GOBP_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | 19/1438 | 66/23056 | 0.2878788 | 4.615670 | 7.586571 | 0.0000000 | 0.0000003 | 0.0000002 | TGFB2/BMP10/PPARG/TGFBR2/BMP3/DAB2/BMP6/HFE/BMPER/INHBA/RBPMS/GDF6/DKK1/BMP4/SMAD6/NOG/GDF15/TGFB1/BMP2 | 19 |
| GOBP_POSITIVE_REGULATION_OF_LIPID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_LIPID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_LIPID_TRANSPORT | 22/1438 | 87/23056 | 0.2528736 | 4.054418 | 7.361584 | 0.0000000 | 0.0000003 | 0.0000002 | LDLRAP1/PLA2G4A/IL1A/IL1B/PPARG/SPP1/DAB2/BMP6/EDN1/CAV1/ACSL5/APOA1/NFKBIA/CYP19A1/ANXA2/CES1/CETP/ABCA8/C1QTNF1/LIPG/TNFRSF11A/APOE | 22 |
| CASTELLANO_NRAS_TARGETS_UP | CASTELLANO_NRAS_TARGETS_UP | CASTELLANO_NRAS_TARGETS_UP | 20/1438 | 73/23056 | 0.2739726 | 4.392707 | 7.487876 | 0.0000000 | 0.0000003 | 0.0000002 | GBP2/CRABP2/IFI16/CFH/SERPINE2/PLSCR2/NPR3/PSMB8/CRYBG1/GJA1/VNN1/PERP/PON3/MEST/ZNF703/ANXA8L1/NQO1/IFI35/USP18/IL13RA1 | 20 |
| GOBP_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 20/1438 | 73/23056 | 0.2739726 | 4.392707 | 7.487876 | 0.0000000 | 0.0000003 | 0.0000002 | CCN1/WWTR1/NPNT/BMP6/RUNX2/TENT5A/FAM20C/IL6/GLI3/CEBPD/CTHRC1/CCN4/YAP1/WNT10B/IGF1/PRKD1/BMP4/BMP2/CEBPB/WNT7B | 20 |
| WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | 20/1438 | 73/23056 | 0.2739726 | 4.392707 | 7.487876 | 0.0000000 | 0.0000003 | 0.0000002 | ATP2B4/IL1R1/PLSCR4/KDR/CFI/C9/DAB2/ID4/CLIC5/CAV1/PODXL/SULF1/GAS1/PTGS1/ANXA8/IFITM2/WT1/IGFBP6/C3/PROCR | 20 |
| GOBP_CAMERA_TYPE_EYE_DEVELOPMENT | GOBP_CAMERA_TYPE_EYE_DEVELOPMENT | GOBP_CAMERA_TYPE_EYE_DEVELOPMENT | 49/1438 | 329/23056 | 0.1489362 | 2.387950 | 6.539658 | 0.0000000 | 0.0000003 | 0.0000002 | EPHA2/RPE65/IGFN1/ATP2B4/TGFB2/WNT9A/EFEMP1/DLX1/DLX2/THRB/TGFBR2/LAMB2/WNT5A/MITF/COL8A1/FOXL2/KDR/SLC7A11/FOXC1/TFAP2A/GJA1/CITED2/INHBA/GLI3/TSPAN12/SHH/KLF4/CRB2/NRP1/PITX3/WT1/PLAAT3/CABP4/FZD4/CRYAB/FLT1/BMP4/FBN1/ALDH1A2/ALDH1A3/SOX8/MAF/LHX1/SOX9/SIX5/BFSP1/BIRC7/WNT7B/NDP | 49 |
| GOBP_POSITIVE_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | GOBP_POSITIVE_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | GOBP_POSITIVE_REGULATION_OF_MORPHOGENESIS_OF_AN_EPITHELIUM | 14/1438 | 36/23056 | 0.3888889 | 6.235203 | 8.107489 | 0.0000000 | 0.0000003 | 0.0000002 | AGT/EGF/GDNF/GJA1/MMRN2/BMP4/SIX1/SIX4/SOX8/LHX1/HOXB7/NOG/SOX9/LIF | 14 |
| UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN | UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN | UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN | 14/1438 | 36/23056 | 0.3888889 | 6.235203 | 8.107489 | 0.0000000 | 0.0000003 | 0.0000002 | CCN1/PTGS2/CXCL8/CXCL2/ELL2/HBEGF/CITED2/PDK4/KLF4/MAP3K8/KCNJ2/KLF2/ZFP36/BMP2 | 14 |
| CHEBOTAEV_GR_TARGETS_DN | CHEBOTAEV_GR_TARGETS_DN | CHEBOTAEV_GR_TARGETS_DN | 27/1438 | 126/23056 | 0.2142857 | 3.435724 | 7.070752 | 0.0000000 | 0.0000003 | 0.0000002 | NEXN/PLA2G4A/PTPN14/TGFB2/PHLDB2/MME/GPAT3/GDNF/TSLP/CHSY3/ARSI/RSPO3/THBS2/PLAT/TNFRSF11B/PPP1R3C/EFEMP2/SLC38A4/PRKD1/ZFP36L1/LOXL1/COTL1/CRISPLD2/SLC14A1/CNN2/MYL9/USP18 | 27 |
| GOBP_CARDIAC_VENTRICLE_DEVELOPMENT | GOBP_CARDIAC_VENTRICLE_DEVELOPMENT | GOBP_CARDIAC_VENTRICLE_DEVELOPMENT | 27/1438 | 126/23056 | 0.2142857 | 3.435724 | 7.070752 | 0.0000000 | 0.0000003 | 0.0000002 | CCN1/TGFB2/BMP10/XIRP2/TGFBR2/TNNC1/WNT5A/HEG1/HES1/FGFRL1/SLIT2/FOXC1/DSP/CITED2/SEMA3C/FZD1/ZFPM2/NOTCH1/FGFR2/BMP4/TPM1/SMAD6/SALL1/FOXF1/MYOCD/NOG/TGFB1 | 27 |
| GOBP_RESPONSE_TO_VIRUS | GOBP_RESPONSE_TO_VIRUS | GOBP_RESPONSE_TO_VIRUS | 55/1438 | 391/23056 | 0.1406650 | 2.255335 | 6.456904 | 0.0000000 | 0.0000003 | 0.0000002 | ZC3H12A/IFI44L/GBP3/GBP1/PTPN22/IFI16/RNASEL/PTPRC/IKBKE/NLRP3/IL1B/NMI/ITGB6/RTP4/SPON2/IL15/DDX60/TLR3/F2RL1/STING1/TRIM38/MICA/MICB/TNFAIP3/ITGB8/IL6/TRIM56/CLU/EXT1/IFNE/DDX58/HTRA1/IFITM2/IFITM3/TSPAN32/TRIM5/FOSL1/BIRC3/HMGA2/OASL/IRF9/NLRC5/MLKL/RNF135/SLFN11/SLFN13/CCL5/DHX58/IL12RB1/BCL3/MX2/MX1/APOBEC3A/APOBEC3G/APOBEC3H | 55 |
| GOMF_CYTOKINE_RECEPTOR_BINDING | GOMF_CYTOKINE_RECEPTOR_BINDING | GOMF_CYTOKINE_RECEPTOR_BINDING | 43/1438 | 270/23056 | 0.1592593 | 2.553464 | 6.622216 | 0.0000000 | 0.0000003 | 0.0000002 | CSF1/ECM1/TNFSF18/TGFB2/IL1A/IL1B/IL36G/CASP8/TGFBR2/IL1RAP/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/IL15/VEGFC/OSMR/TSLP/CSF2/IL6/CCL26/TRIP6/IFNE/TNFSF15/TRAF1/ITGA5/TNFSF13B/SMAD6/CTF1/CCL5/CSF3/EBI3/TNFSF9/CD70/TNFSF14/IL27RA/IL12RB1/TGFB1/IL11/LIF/IL13RA1 | 43 |
| GOBP_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS | GOBP_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS | GOBP_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS | 18/1438 | 60/23056 | 0.3000000 | 4.810014 | 7.621322 | 0.0000000 | 0.0000003 | 0.0000002 | S1PR1/TGFB2/BMP10/XIRP2/TNNC1/WNT5A/HEG1/FOXC1/DSP/ZFPM2/NOTCH1/ANKRD1/FGFR2/ACTC1/TPM1/NOG/TGFB1/BMP2 | 18 |
| WP_CYTOKINES_AND_INFLAMMATORY_RESPONSE | WP_CYTOKINES_AND_INFLAMMATORY_RESPONSE | WP_CYTOKINES_AND_INFLAMMATORY_RESPONSE | 12/1438 | 26/23056 | 0.4615385 | 7.400021 | 8.421227 | 0.0000000 | 0.0000003 | 0.0000002 | CSF1/IL1A/IL1B/CXCL1/CXCL2/IL15/CSF2/PDGFA/IL6/CSF3/TGFB1/IL11 | 12 |
| MOSERLE_IFNA_RESPONSE | MOSERLE_IFNA_RESPONSE | MOSERLE_IFNA_RESPONSE | 13/1438 | 31/23056 | 0.4193548 | 6.723675 | 8.224514 | 0.0000000 | 0.0000003 | 0.0000002 | IFI44L/GBP1/IFI16/RTP4/DDX60/DDX60L/SAMD9/SAMD9L/CD274/DDX58/OASL/MX1/USP18 | 13 |
| SANSOM_APC_TARGETS_DN | SANSOM_APC_TARGETS_DN | SANSOM_APC_TARGETS_DN | 52/1438 | 361/23056 | 0.1440443 | 2.309517 | 6.467761 | 0.0000000 | 0.0000003 | 0.0000002 | EDN2/GBP2/CD53/RHOC/S100A13/PTPRC/IKBKE/VAMP5/LCT/MLPH/AADAC/SOD3/JCHAIN/SLC4A4/NPR3/TGFBI/GALNT10/ADAM19/HLA-E/GPSM3/RUNX2/AKR1B10/ZNF467/IDO1/PCSK5/SRGN/PAPSS2/FAS/PTPRE/SLC22A18/CD82/CASP1/ARHGDIB/SOAT2/SELPLG/BMP4/CCL5/FMNL1/GIP/ITGA3/ABCC3/MOCOS/CD70/IL12RB1/CD22/TGFB1/IL4I1/SIRPA/GGT1/IL2RB/RAC2/COL4A5 | 52 |
| GOBP_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION | 24/1438 | 103/23056 | 0.2330097 | 3.735933 | 7.177259 | 0.0000000 | 0.0000003 | 0.0000002 | VCAM1/PTPN22/PTPRC/IL1A/IL1B/TGFBR2/HES1/IL15/HLA-E/IL6/SHH/CD274/PDCD1LG2/ANXA1/NCKAP1L/IGF1/TNFSF13B/CCL5/EBI3/TNFSF9/CD70/IL27RA/IL12RB1/ICOSLG | 24 |
| GOBP_CRANIAL_NERVE_DEVELOPMENT | GOBP_CRANIAL_NERVE_DEVELOPMENT | GOBP_CRANIAL_NERVE_DEVELOPMENT | 17/1438 | 54/23056 | 0.3148148 | 5.047546 | 7.679980 | 0.0000000 | 0.0000003 | 0.0000002 | NRP2/ACKR3/HES1/TFAP2A/CITED2/HOXA1/HOXA3/GLI3/SEMA3A/EXT1/NRP1/SIX1/SIX4/SLC24A4/SALL1/HOXB2/HOXB3 | 17 |
| HARRIS_HYPOXIA | HARRIS_HYPOXIA | HARRIS_HYPOXIA | 21/1438 | 81/23056 | 0.2592593 | 4.156802 | 7.340343 | 0.0000000 | 0.0000003 | 0.0000002 | EDN2/PTGS2/TGFA/BHLHE40/CXCL8/SPP1/EDN1/IL6/STC1/TEK/COL5A1/ADM/TAGLN/FLT1/FOS/CA12/TGFB1/TGM2/HMOX1/PDGFB/SAT1 | 21 |
| CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | 30/1438 | 152/23056 | 0.1973684 | 3.164483 | 6.905172 | 0.0000000 | 0.0000003 | 0.0000002 | AGRN/S100A13/LAMC2/CD34/CAPG/VAMP5/COL5A2/BHLHE40/PLAC8/DAB2/ADRB2/CCN2/UTRN/SKAP2/AQP1/SEMA3C/KLF4/ANXA8L1/PAPSS2/ADM/PRSS23/TNS2/STAT6/FBN1/MSLN/NUPR1/ITGB4/KLF2/FXYD5/EMP3 | 30 |
| DELYS_THYROID_CANCER_DN | DELYS_THYROID_CANCER_DN | DELYS_THYROID_CANCER_DN | 39/1438 | 233/23056 | 0.1673820 | 2.683699 | 6.662086 | 0.0000000 | 0.0000003 | 0.0000002 | CCN1/LRP1B/CYBRD1/TFPI/AOX1/ACKR3/EPHA3/SLC4A4/IQGAP2/ID4/PLA2G7/LAMA2/CITED2/CD36/SEMA3D/SLC26A4/PTN/ASPH/MATN2/ZFPM2/TNFRSF11B/TEK/GAS1/HHEX/FGFR2/CRYAB/RERGL/FOS/DIO2/FBLN5/ALDH1A2/MT1X/COPZ2/ACSF2/SLC14A1/LIPG/BMP2/COL9A3/ITM2A | 39 |
| FOROUTAN_INTEGRATED_TGFB_EMT_DN | FOROUTAN_INTEGRATED_TGFB_EMT_DN | FOROUTAN_INTEGRATED_TGFB_EMT_DN | 20/1438 | 74/23056 | 0.2702703 | 4.333346 | 7.407243 | 0.0000000 | 0.0000003 | 0.0000002 | CFH/ELF3/CAVIN2/RBM47/EREG/SERPINB1/PDK4/CEBPD/AQP3/EHF/PLAAT4/BIRC3/MPZL2/SCNN1A/EMP1/ALDH1A3/KRT15/KRT19/MBP/GDF15 | 20 |
| EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION | EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION | EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION | 16/1438 | 48/23056 | 0.3333333 | 5.344460 | 7.770898 | 0.0000000 | 0.0000003 | 0.0000002 | DES/COL6A3/TNNC1/MYO10/HBEGF/ABLIM3/UTRN/CRYAB/TAGLN/TPM1/CTF1/MYH8/MYH1/MYL4/MYOM1/SMPX | 16 |
| CAIRO_LIVER_DEVELOPMENT_DN | CAIRO_LIVER_DEVELOPMENT_DN | CAIRO_LIVER_DEVELOPMENT_DN | 38/1438 | 224/23056 | 0.1696429 | 2.719948 | 6.671472 | 0.0000000 | 0.0000004 | 0.0000002 | CFH/AGT/NID1/NABP1/CPS1/FN1/ITIH3/ALDH1L1/CLDN1/PLAC8/C9/HLA-E/TAPBP/TENT5A/AQP1/PON3/MATN2/ANXA1/GSN/ALOX5AP/LCP1/SLC7A7/PYGL/SERPINA10/SERPINA1/ORAI3/CES1/CD68/ABCA8/TNFRSF11A/ELANE/C3/ADGRE1/B3GNT3/APOE/COL18A1/HMOX1/KDELR3 | 38 |
| HALLMARK_UV_RESPONSE_DN | HALLMARK_UV_RESPONSE_DN | HALLMARK_UV_RESPONSE_DN | 29/1438 | 144/23056 | 0.2013889 | 3.228944 | 6.919955 | 0.0000000 | 0.0000004 | 0.0000002 | CCN1/ATP2B4/LTBP1/EFEMP1/TFPI/COL3A1/COL5A2/BHLHE40/PPARG/TGFBR2/MGLL/INPP4B/DAB2/CAP2/GJA1/CITED2/SYNJ2/SERPINE1/CAV1/MET/RBPMS/HAS2/NRP1/SLC22A18/FBLN5/ANXA2/COL1A1/CACNA1A/RUNX1 | 29 |
| HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_UP | 18/1438 | 61/23056 | 0.2950820 | 4.731161 | 7.525693 | 0.0000000 | 0.0000004 | 0.0000002 | CSF1/S100A2/NT5E/LAMA4/THBS2/PLAT/PLAU/HHEX/PRSS23/PHLDA1/LUM/LCP1/IL32/MT2A/MT1X/MAF/CD68/ITM2A | 18 |
| HOOI_ST7_TARGETS_DN | HOOI_ST7_TARGETS_DN | HOOI_ST7_TARGETS_DN | 26/1438 | 120/23056 | 0.2166667 | 3.473899 | 7.007579 | 0.0000000 | 0.0000004 | 0.0000003 | TRABD2B/CCDC141/FN1/GXYLT2/TM4SF1/KDR/DNAH5/SPARC/SLC22A23/PLA2G7/ITGB8/CADPS2/CSGALNACT1/RBPMS/AKR1C3/CREB3L1/MMP10/MMP1/NNMT/VWA5A/CRIP1/COL1A1/NOG/SLC14A1/APOBEC3G/TBC1D8B | 26 |
| MAHADEVAN_IMATINIB_RESISTANCE_UP | MAHADEVAN_IMATINIB_RESISTANCE_UP | MAHADEVAN_IMATINIB_RESISTANCE_UP | 11/1438 | 22/23056 | 0.5000000 | 8.016690 | 8.492063 | 0.0000000 | 0.0000004 | 0.0000003 | CRIM1/KYNU/SERPINE2/PDGFC/MYO10/NNMT/AXL/SPANXB1/SPANXC/SPANXA1/SPANXA2 | 11 |
| REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS | REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS | REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS | 19/1438 | 68/23056 | 0.2794118 | 4.479915 | 7.411852 | 0.0000000 | 0.0000004 | 0.0000003 | ADAMTSL4/GALNT3/MUC13/SPON2/ADAMTS3/ADAMTS16/SEMA5A/ADAMTS12/ADAMTS6/ADAMTS2/THBS2/NOTCH1/ADAMTS8/ADAMTS15/THBS1/ADAMTS18/ADAMTSL5/MUC16/ADAMTS5 | 19 |
| BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | 36/1438 | 207/23056 | 0.1739130 | 2.788414 | 6.666131 | 0.0000000 | 0.0000004 | 0.0000003 | TNFRSF1B/GBP4/GBP5/VCAM1/CTSS/CASP10/CDCP1/IL15/CCDC69/MICB/PSMB8/PSMB9/SOD2/CEBPD/CD274/IL15RA/SRGN/AIFM2/ANKRD22/NFKB2/ACSL5/BIRC3/C1S/C1RL/STYK1/YBX3/DRAM1/TNFAIP2/IL32/PSMB10/SOCS3/ICAM1/IL27RA/IL12RB1/APOE/RELB | 36 |
| GOBP_BIOMINERALIZATION | GOBP_BIOMINERALIZATION | GOBP_BIOMINERALIZATION | 32/1438 | 171/23056 | 0.1871345 | 3.000399 | 6.771632 | 0.0000000 | 0.0000004 | 0.0000003 | CCN1/S1PR1/ECM1/PTGS2/OSR1/ITGB6/FGFR3/AMTN/ENAM/SPP1/SGMS2/ADRB2/BMP6/TFAP2A/TENT5A/GJA1/FAM20C/PTN/RSPO2/NOTCH1/ALOX5/SRGN/FGFR2/WNT10B/IGF1/BMP4/SLC24A4/COL1A1/SOX9/TGFB1/BMP2/CEBPB | 32 |
| GOBP_POSITIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 42/1438 | 264/23056 | 0.1590909 | 2.550765 | 6.535984 | 0.0000000 | 0.0000004 | 0.0000003 | RNF220/TNFSF18/RAB7B/IKBKE/AGT/NLRP3/IL1B/IRAK2/PPARG/WNT5A/IL1RAP/ANXA3/TLR3/TRIML2/TRIML1/STING1/EDN1/TRIM38/IL6/CD36/FZD1/CAV1/ARHGEF5/SHH/CLU/ADCY8/DDX58/TRAF1/FANK1/TRIM5/FOSL1/FZD4/CARD16/WNT10B/ZIC2/PRKD1/MYOCD/CSF3/JUP/TNFRSF11A/BMP2/NDP | 42 |
| RICKMAN_HEAD_AND_NECK_CANCER_F | RICKMAN_HEAD_AND_NECK_CANCER_F | RICKMAN_HEAD_AND_NECK_CANCER_F | 17/1438 | 55/23056 | 0.3090909 | 4.955772 | 7.575189 | 0.0000000 | 0.0000004 | 0.0000003 | NEXN/XIRP2/DES/TNNC1/HSPB3/PDK4/ZFPM2/TPM2/IGF1/ACTC1/TPM1/MYH1/MYH2/ABCA8/CKM/PTGIS/SMPX | 17 |
| GOBP_ENTRY_INTO_HOST | GOBP_ENTRY_INTO_HOST | GOBP_ENTRY_INTO_HOST | 30/1438 | 154/23056 | 0.1948052 | 3.123386 | 6.818782 | 0.0000000 | 0.0000005 | 0.0000003 | TNFRSF4/EPHA2/ITGB6/ITGB5/CLDN1/CXCL8/GYPA/TRIML2/TRIML1/ITGA2/TRIM38/MOG/FUCA2/CAV2/CAV1/GSN/NRP1/IFITM2/IFITM3/TRIM5/ITGA5/SELPLG/TPCN1/ANPEP/CLDN6/CLEC4M/ICAM1/AXL/NECTIN2/LGALS1 | 30 |
| GOBP_GRANULOCYTE_MIGRATION | GOBP_GRANULOCYTE_MIGRATION | GOBP_GRANULOCYTE_MIGRATION | 30/1438 | 154/23056 | 0.1948052 | 3.123386 | 6.818782 | 0.0000000 | 0.0000005 | 0.0000003 | EDN2/MCOLN2/CSF1/TGFB2/IL1R1/IL1A/IL1B/DPP4/HRH1/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EDN1/CCL26/RARRES2/ANXA1/SAA1/C3AR1/NCKAP1L/THBS1/CCL5/CCR7/PECAM1/C5AR1/RAC2/XG | 30 |
| GOBP_REGULATION_OF_KIDNEY_DEVELOPMENT | GOBP_REGULATION_OF_KIDNEY_DEVELOPMENT | GOBP_REGULATION_OF_KIDNEY_DEVELOPMENT | 13/1438 | 32/23056 | 0.4062500 | 6.513560 | 8.049539 | 0.0000000 | 0.0000005 | 0.0000003 | AGT/OSR1/GDNF/FOXD1/WT1/BMP4/SIX1/SIX4/SOX8/LHX1/HOXB7/NOG/SOX9 | 13 |
| GOBP_MONONUCLEAR_CELL_MIGRATION | GOBP_MONONUCLEAR_CELL_MIGRATION | GOBP_MONONUCLEAR_CELL_MIGRATION | 35/1438 | 199/23056 | 0.1758794 | 2.819941 | 6.650105 | 0.0000000 | 0.0000005 | 0.0000003 | S1PR1/CSF1/ECM1/ITGA4/WNT5A/SLIT2/ADTRP/PLA2G7/IL6/CCL26/SERPINE1/ARHGEF5/RARRES2/EXT1/ANXA1/ALOX5/SAA1/C3AR1/KLRC4-KLRK1/EPS8/FLT1/THBS1/CCL5/CCR7/PECAM1/TNFRSF11A/TNFSF14/ICAM1/IL27RA/C5AR1/SIRPA/DEFB124/PDGFB/XG/MSN | 35 |
| GOBP_URETER_DEVELOPMENT | GOBP_URETER_DEVELOPMENT | GOBP_URETER_DEVELOPMENT | 10/1438 | 18/23056 | 0.5555556 | 8.907433 | 8.655729 | 0.0000000 | 0.0000005 | 0.0000003 | OSR1/TBX18/SHH/BMP4/SIX1/ALDH1A2/SOX8/FOXF1/LHX1/SOX9 | 10 |
| REACTOME_SYNDECAN_INTERACTIONS | REACTOME_SYNDECAN_INTERACTIONS | REACTOME_SYNDECAN_INTERACTIONS | 12/1438 | 27/23056 | 0.4444444 | 7.125947 | 8.214323 | 0.0000000 | 0.0000005 | 0.0000003 | ITGA6/COL3A1/COL5A2/FN1/ITGB5/ITGA2/COL5A1/THBS1/COL1A1/ITGB4/TGFB1/SDC4 | 12 |
| JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 18/1438 | 62/23056 | 0.2903226 | 4.654852 | 7.432119 | 0.0000000 | 0.0000005 | 0.0000003 | ITGB5/BCL6/PLK2/ID4/CCN2/NRP1/FZD8/HMGA2/BMP4/FOS/THBS1/GRB7/JUP/KLF2/ZFP36/TGM2/MYH9/SAT1 | 18 |
| NAKAMURA_ADIPOGENESIS_EARLY_UP | NAKAMURA_ADIPOGENESIS_EARLY_UP | NAKAMURA_ADIPOGENESIS_EARLY_UP | 18/1438 | 62/23056 | 0.2903226 | 4.654852 | 7.432119 | 0.0000000 | 0.0000005 | 0.0000003 | IL22RA1/NID1/IL1R1/CYBRD1/COL6A3/COL8A1/P3H2/GASK1B/SMIM3/SOD2/CEBPD/GAS1/S1PR3/DKK1/NFE2/FOXO1/GADD45B/ZFP36 | 18 |
| GOBP_SENSORY_ORGAN_MORPHOGENESIS | GOBP_SENSORY_ORGAN_MORPHOGENESIS | GOBP_SENSORY_ORGAN_MORPHOGENESIS | 42/1438 | 266/23056 | 0.1578947 | 2.531586 | 6.479841 | 0.0000000 | 0.0000005 | 0.0000003 | EPHA2/RPE65/PRRX1/IGFN1/WNT9A/OSR1/EFEMP1/CYP26B1/COL5A2/THRB/RARB/WNT5A/COL8A1/FOXL2/NKX3-2/KDR/TFAP2A/EDN1/TBX18/CITED2/HOXA1/HOXA2/GLI3/TSPAN12/FZD6/CTHRC1/CRB2/COL5A1/ITGA8/PITX3/FGFR2/HMX3/CABP4/BMP4/SIX1/SIX4/FBN1/ALDH1A3/SOX8/LHX1/NOG/SOX9 | 42 |
| KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | 27/1438 | 130/23056 | 0.2076923 | 3.330010 | 6.870993 | 0.0000000 | 0.0000005 | 0.0000004 | RNASEL/TGFB2/IL1R1/IL1A/IL1B/WNT5A/RTP4/CXCL8/EREG/TLR3/GJA1/PERP/IL6/FZD1/CAV1/TNFRSF10A/PLAT/PLAU/FAS/BIRC3/CASP1/LUM/NFKBIA/TNFRSF12A/MMP2/BMP2/BGN | 27 |
| GOBP_ARTERY_DEVELOPMENT | GOBP_ARTERY_DEVELOPMENT | GOBP_ARTERY_DEVELOPMENT | 24/1438 | 106/23056 | 0.2264151 | 3.630199 | 7.000104 | 0.0000000 | 0.0000006 | 0.0000004 | PRRX1/TGFB2/COL3A1/MYLK/HES1/ADAMTS6/FOXC1/EDN1/ADGRF5/CITED2/HOXA1/GLI3/SHH/NOTCH1/NRP1/EFEMP2/BMP4/SIX1/SMAD6/LOXL1/FOXF1/MYOCD/NOG/APOE | 24 |
| GOBP_CARDIAC_SEPTUM_DEVELOPMENT | GOBP_CARDIAC_SEPTUM_DEVELOPMENT | GOBP_CARDIAC_SEPTUM_DEVELOPMENT | 24/1438 | 106/23056 | 0.2264151 | 3.630199 | 7.000104 | 0.0000000 | 0.0000006 | 0.0000004 | DHRS3/CCN1/TGFB2/XIRP2/NRP2/TGFBR2/WNT5A/HEG1/HES1/FGFRL1/SLIT2/ADAMTS6/CITED2/SEMA3C/FZD1/ZFPM2/NOTCH1/NRP1/FGFR2/BMP4/SMAD6/SALL1/NOG/GATA6 | 24 |
| GOCC_PLASMA_MEMBRANE_RAFT | GOCC_PLASMA_MEMBRANE_RAFT | GOCC_PLASMA_MEMBRANE_RAFT | 25/1438 | 114/23056 | 0.2192982 | 3.516092 | 6.945725 | 0.0000000 | 0.0000006 | 0.0000004 | PTGS2/ATP2B4/TFPI/CAVIN2/TGFBR2/GASK1A/ADTRP/CD36/CAV2/CAV1/HAS2/ADCY8/MYOF/MS4A4A/KCNA5/SELPLG/TRPC4/CDH13/CDH15/CAVIN1/PLVAP/EHD2/PTGIS/HMOX1/MLC1 | 25 |
| GOCC_PLATELET_ALPHA_GRANULE | GOCC_PLATELET_ALPHA_GRANULE | GOCC_PLATELET_ALPHA_GRANULE | 22/1438 | 91/23056 | 0.2417582 | 3.876202 | 7.090242 | 0.0000000 | 0.0000006 | 0.0000004 | TGFB2/FN1/SERPINE2/EGF/VEGFC/SPARC/TREML1/CD109/THBS2/PDGFA/CD36/SERPINE1/CLU/TOR4A/SRGN/VWF/IGF1/SERPINA1/THBS1/PECAM1/TGFB1/PDGFB | 22 |
| CAIRO_HEPATOBLASTOMA_DN | CAIRO_HEPATOBLASTOMA_DN | CAIRO_HEPATOBLASTOMA_DN | 42/1438 | 267/23056 | 0.1573034 | 2.522105 | 6.451962 | 0.0000000 | 0.0000006 | 0.0000004 | EPHA2/CDA/ZC3H12A/ECM1/PRG4/SRD5A2/VIPR1/STAB1/MGLL/IL1RAP/TDO2/C9/CRHBP/ABLIM3/PXDC1/CYP39A1/TENT5A/VNN1/SLC22A1/SERPINE1/EXT1/AQP3/PAPSS2/CYP26A1/ADM/BBOX1/PLAAT3/NNMT/C1R/C1RL/SLC38A4/IGF1/SLC46A3/FOXO1/IL4R/CETP/MYOM1/SERPINB8/CLEC4M/CYP4F11/CHST7/TENM1 | 42 |
| GOMF_PEPTIDE_BINDING | GOMF_PEPTIDE_BINDING | GOMF_PEPTIDE_BINDING | 48/1438 | 327/23056 | 0.1467890 | 2.353524 | 6.357755 | 0.0000000 | 0.0000006 | 0.0000004 | ECE1/HSPG2/LDLRAP1/TGFB2/SCTR/EPHA4/PPARG/VIPR1/TMEM158/MME/NPR3/ITGA2/CRHBP/ERAP2/LVRN/PPIC/ADRB2/HFE/HLA-E/HLA-C/TAPBP/HCRTR2/INHBA/CD36/GPR37/MSR1/CLU/FZD6/PCSK5/NPY4R2/NLRP6/CCKBR/FZD4/CRYAB/APOA1/EDNRB/NFKBIA/BDKRB1/CRIP1/ANPEP/GLP2R/EBI3/CLEC4M/CACNA1A/APOE/PRNP/KDELR3/ITM2A | 48 |
| GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION | 44/1438 | 287/23056 | 0.1533101 | 2.458079 | 6.410683 | 0.0000000 | 0.0000006 | 0.0000004 | TNFRSF4/EPHA2/ZC3H12A/ITGB6/FN1/ITGB5/CLDN1/LRRC15/CXCL8/CXCL6/LEF1/GYPA/TRIML2/TRIML1/ITGA2/F2RL1/TRIM38/MOG/FUCA2/CAV2/CAV1/GSN/NRP1/MBL2/SFTPD/NLRP6/IFITM2/IFITM3/TRIM5/ITGA5/HMGA2/SELPLG/TPCN1/ANPEP/CLDN6/CCL5/ELANE/CLEC4M/ICAM1/AXL/NECTIN2/APOE/APOL1/LGALS1 | 44 |
| WIERENGA_STAT5A_TARGETS_UP | WIERENGA_STAT5A_TARGETS_UP | WIERENGA_STAT5A_TARGETS_UP | 35/1438 | 201/23056 | 0.1741294 | 2.791882 | 6.580685 | 0.0000000 | 0.0000006 | 0.0000004 | TNFRSF4/DHRS3/GBP4/FCGR2A/CFH/BHLHE40/XIRP1/FNDC3B/P3H2/CXCL8/GPAT3/SPP1/MYO10/IL7R/DAB2/ITGA2/F2RL1/CSF2/RHAG/TRAF1/PLAU/ADM/SLC2A14/EMP1/PHLDA1/TNFAIP8L3/IL4R/CCL5/CCR7/GADD45B/KLF2/PLVAP/IL4I1/TGM2/A4GALT | 35 |
| GOBP_HEART_PROCESS | GOBP_HEART_PROCESS | GOBP_HEART_PROCESS | 41/1438 | 258/23056 | 0.1589147 | 2.547940 | 6.448666 | 0.0000000 | 0.0000006 | 0.0000004 | HSPB7/ZC3H12A/EDN2/ATP2B4/TGFB2/AGT/BMP10/DES/KCNE4/THRB/TNNC1/WWTR1/HBEGF/DSP/EDN1/TBX18/GJA1/TRDN/CCN2/MYL7/SEMA3A/CAV1/STC1/EXT1/GSN/RNLS/ADM/YAP1/KCNA5/SPX/EDNRB/ACTC1/TPM1/HCN4/JUP/MYL4/KCNJ2/GATA6/DSG2/SCN1B/ADRA1D | 41 |
| GOBP_REGULATION_OF_LIPID_LOCALIZATION | GOBP_REGULATION_OF_LIPID_LOCALIZATION | GOBP_REGULATION_OF_LIPID_LOCALIZATION | 33/1438 | 183/23056 | 0.1803279 | 2.891265 | 6.624768 | 0.0000000 | 0.0000006 | 0.0000004 | LDLRAP1/ZC3H12A/PLA2G4A/IKBKE/AGT/IL1A/IL1B/PPARG/SPP1/EGF/DAB2/BMP6/EDN1/IL6/CD36/CAV1/SHH/MSR1/ACSL5/APOC3/APOA1/NFKBIA/THBS1/CYP19A1/ANXA2/CES1/CETP/ABCA8/C1QTNF1/LIPG/TNFRSF11A/C3/APOE | 33 |
| WORSCHECH_TUMOR_REJECTION_UP | WORSCHECH_TUMOR_REJECTION_UP | WORSCHECH_TUMOR_REJECTION_UP | 18/1438 | 63/23056 | 0.2857143 | 4.580966 | 7.340521 | 0.0000000 | 0.0000006 | 0.0000004 | TNFRSF4/TNFRSF1B/IFI16/IL1A/IL1B/IL36G/IL1RAP/JCHAIN/CXCL3/CXCL2/IL7R/MSR1/KLRD1/STAT6/BCL2A1/CCL5/IL4I1/MX1 | 18 |
| GOBP_REGULATION_OF_CELL_MATRIX_ADHESION | GOBP_REGULATION_OF_CELL_MATRIX_ADHESION | GOBP_REGULATION_OF_CELL_MATRIX_ADHESION | 26/1438 | 123/23056 | 0.2113821 | 3.389170 | 6.852095 | 0.0000000 | 0.0000007 | 0.0000004 | CSF1/S100A10/EPHA3/PHLDB2/BCL6/KDR/DDR1/UTRN/HOXA7/CD36/SERPINE1/PLEKHA2/TEK/NRP1/PLAU/VCL/PTPRJ/EFEMP2/MMP14/THBS1/CDH13/CCR7/JUP/RRAS/RIN2/SDC4 | 26 |
| GOBP_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | GOBP_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | GOBP_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | 24/1438 | 107/23056 | 0.2242991 | 3.596272 | 6.942477 | 0.0000000 | 0.0000007 | 0.0000004 | TNFRSF18/TNFRSF4/TNFRSF1B/TNFSF18/CASP8/F2RL1/TNFAIP3/EXT1/TRAF1/FAS/BIRC3/CASP4/CASP1/CARD16/APOA1/TNFRSF1A/KRT18/TNFRSF19/TNFSF13B/NFKBIA/TNFRSF11A/CD70/PLVAP/BIRC7 | 24 |
| MARZEC_IL2_SIGNALING_UP | MARZEC_IL2_SIGNALING_UP | MARZEC_IL2_SIGNALING_UP | 25/1438 | 115/23056 | 0.2173913 | 3.485517 | 6.891501 | 0.0000000 | 0.0000007 | 0.0000004 | TNFRSF18/TNFRSF4/TNFRSF9/TNFRSF1B/PTPN7/IL1A/CXCL8/SPP1/CSF2/IER3/TNFRSF21/AHR/TNFRSF10A/PHLDA2/WT1/BIRC3/PHLDA1/TNFRSF12A/GADD45B/TNFSF14/TGFB1/BMP2/LIF/IL2RB/CARD10 | 25 |
| ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | 28/1438 | 140/23056 | 0.2000000 | 3.206676 | 6.754410 | 0.0000000 | 0.0000007 | 0.0000005 | CFH/LTBP1/RASGRP3/HNMT/CAVIN2/LAMB2/SNCAIP/FOXC1/HOXA1/HOXA2/HOXA7/CLU/ASPH/AQP3/WT1/RAB38/C3AR1/KRT18/ITGA5/LUM/DRAM1/MMP2/HOXB2/HOXB3/HOXB7/PIEZO2/ADGRE1/COL4A5 | 28 |
| MARTENS_BOUND_BY_PML_RARA_FUSION | MARTENS_BOUND_BY_PML_RARA_FUSION | MARTENS_BOUND_BY_PML_RARA_FUSION | 60/1438 | 456/23056 | 0.1315789 | 2.109655 | 6.172634 | 0.0000000 | 0.0000007 | 0.0000005 | TNFRSF4/ECE1/RUNX3/ZC3H12A/ADCY10/ATP2B4/NUAK2/WNT9A/NLRP3/CAPG/ITGA4/BHLHE40/MGLL/ZFYVE28/PLAC8/STING1/SMIM3/SERPINB1/TNFAIP3/INHBA/HECW1/PLEKHA2/B4GALT1/S1PR3/NEK6/APBB1IP/IFITM3/C11orf21/CD82/PTPRJ/P2RY2/MAML2/UBASH3B/NFE2/LATS2/FLT3/ALOX5AP/RAB20/TNFAIP2/GPR132/UACA/CETP/COTL1/FMNL1/RHBDF2/TMC8/MBP/ICAM1/KLF2/SLC7A10/BCL3/C5AR1/SIRPA/RUNX1/MX2/MN1/HMOX1/MYH9/RAC2/CYTH4 | 60 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | 34/1438 | 193/23056 | 0.1761658 | 2.824533 | 6.564748 | 0.0000000 | 0.0000007 | 0.0000005 | RUNX3/LDLRAP1/CSF1/PTPN22/FCGR2A/CAPG/ITGA6/STAB1/TMEM156/PLAC8/IL7R/TGFBI/GMPR/CD36/DOK2/AQP3/C11orf21/HBD/MICAL2/CD82/BIRC3/NFE2/SELPLG/TPCN1/ALOX5AP/TPM1/ANPEP/LAT/MMP2/CCR7/MYL4/SLC16A3/MBP/LGALS1 | 34 |
| DUTTA_APOPTOSIS_VIA_NFKB | DUTTA_APOPTOSIS_VIA_NFKB | DUTTA_APOPTOSIS_VIA_NFKB | 13/1438 | 33/23056 | 0.3939394 | 6.316180 | 7.881882 | 0.0000000 | 0.0000007 | 0.0000005 | CASP8/IER3/TNFRSF21/TNFAIP3/SOD2/TNFRSF10C/TNFRSF10A/CD274/TRAF1/FAS/BIRC3/BCL2A1/GADD45B | 13 |
| SIMBULAN_UV_RESPONSE_NORMAL_DN | SIMBULAN_UV_RESPONSE_NORMAL_DN | SIMBULAN_UV_RESPONSE_NORMAL_DN | 13/1438 | 33/23056 | 0.3939394 | 6.316180 | 7.881882 | 0.0000000 | 0.0000007 | 0.0000005 | ITGA6/ADRB2/PTP4A1/RBPMS/HAS2/AHNAK/EMP1/PHLDA1/THBS1/GRB7/ITGB4/GADD45B/MN1 | 13 |
| GOBP_REGULATION_OF_PEPTIDASE_ACTIVITY | GOBP_REGULATION_OF_PEPTIDASE_ACTIVITY | GOBP_REGULATION_OF_PEPTIDASE_ACTIVITY | 60/1438 | 457/23056 | 0.1312910 | 2.105039 | 6.153827 | 0.0000000 | 0.0000008 | 0.0000005 | CCN1/ECM1/IFI16/PTGS2/AGT/NLRP3/CRIM1/TFPI/CASP10/CASP8/FN1/EPHA4/SERPINE2/COL6A3/PPARG/COL7A1/ITIH3/FOXL2/SERPINB1/PSMB8/PSMB9/CD109/CCN2/PERP/AQP1/SERPINE1/CAV1/ASPH/KLF4/TNFSF15/GSN/CRB2/ANXA8L1/ANXA8/FAS/NLRP6/CD44/SERPINH1/BIRC3/CASP4/CASP1/CARD16/CRYAB/BLID/SERPINE3/SERPINA10/SERPINA6/SERPINA1/THBS1/ANXA2/UACA/SERPINB7/SERPINB2/SERPINB8/MBP/TNFSF14/C3/PRNP/WFDC10B/BIRC7 | 60 |
| GOBP_RESPONSE_TO_STEROID_HORMONE | GOBP_RESPONSE_TO_STEROID_HORMONE | GOBP_RESPONSE_TO_STEROID_HORMONE | 48/1438 | 330/23056 | 0.1454545 | 2.332128 | 6.286308 | 0.0000000 | 0.0000008 | 0.0000005 | ERRFI1/TRIM63/PTGS2/TGFB2/LBH/SRD5A2/TFPI/CPS1/TGFBR2/CLDN1/SLIT2/ANXA3/SPP1/DAB2/ZNF366/PCSK1/SOX30/BMP6/ADTRP/EDN1/CCN2/IL6/AQP1/CAV1/STC1/ADAM9/PLAT/FBXO32/ANXA1/PAPPA/NOTCH1/AKR1C3/ADM/FIBIN/FOSL1/PGR/YAP1/FLT3/BMP4/ZFP36L1/FOS/ESRRB/THBS1/COL1A1/MBP/ZFP36/TGFB1/WNT7B | 48 |
| GOBP_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | GOBP_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | GOBP_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | 26/1438 | 124/23056 | 0.2096774 | 3.361838 | 6.801335 | 0.0000000 | 0.0000008 | 0.0000005 | EDN2/CSF1/DPP4/WNT5A/SLIT2/CXCL8/VEGFC/F2RL1/EDN1/GPSM3/PLA2G7/IL6/SERPINE1/PTN/RARRES2/C3AR1/KLRC4-KLRK1/NCKAP1L/THBS1/CYP19A1/CCL5/CCR7/TNFSF14/C5AR1/DEFB124/RAC2 | 26 |
| GOBP_PROSTATE_GLAND_MORPHOGENESIS | GOBP_PROSTATE_GLAND_MORPHOGENESIS | GOBP_PROSTATE_GLAND_MORPHOGENESIS | 12/1438 | 28/23056 | 0.4285714 | 6.871448 | 8.017711 | 0.0000000 | 0.0000008 | 0.0000005 | WNT5A/ID4/SHH/SULF1/NOTCH1/FGFR2/BMP4/CRIP1/MMP2/HOXB13/NOG/SOX9 | 12 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | 35/1438 | 203/23056 | 0.1724138 | 2.764376 | 6.512110 | 0.0000000 | 0.0000008 | 0.0000005 | IFI44L/GBP1/CSF1/TFPI/TMEM158/TM4SF1/CRHBP/DDR1/SASH1/PDGFA/AQP1/INHBA/TRIP6/EXT1/GPR20/AKR1C3/MYOF/TCF7L2/MYRF/MMP10/MMP1/EPS8/ALDH1A2/BCL2A1/MT2A/MT1X/ADAP2/CAVIN1/GDF15/KCNN4/APOE/EHD2/MX1/USP18/PLS3 | 35 |
| YAMAZAKI_TCEB3_TARGETS_UP | YAMAZAKI_TCEB3_TARGETS_UP | YAMAZAKI_TCEB3_TARGETS_UP | 31/1438 | 167/23056 | 0.1856287 | 2.976256 | 6.610622 | 0.0000000 | 0.0000008 | 0.0000005 | HSPG2/CCN1/NID1/TFPI/AMOTL2/LPP/SPARC/CITED2/EPHB4/MDFIC/ZYX/TNFRSF10A/CLU/PLAT/EXT1/SRGN/CYP26A1/TCF7L2/CREB3L1/EFEMP2/SERPINH1/CRYAB/MPZL2/NID2/ANXA2/MFGE8/GATA6/THBD/CDC42EP1/KDELR3/COL4A5 | 31 |
| BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE | 20/1438 | 78/23056 | 0.2564103 | 4.111123 | 7.098435 | 0.0000000 | 0.0000008 | 0.0000005 | IFI44L/GBP4/ITGA4/ARAP2/TNIP3/DDX60/SAMD9L/PARP12/CD274/IFITM3/OASL/LAT/DHX58/IFI35/RIN2/CYP24A1/MX1/APOL6/APOL1/APOBEC3G | 20 |
| GOCC_ACTIN_FILAMENT_BUNDLE | GOCC_ACTIN_FILAMENT_BUNDLE | GOCC_ACTIN_FILAMENT_BUNDLE | 20/1438 | 78/23056 | 0.2564103 | 4.111123 | 7.098435 | 0.0000000 | 0.0000008 | 0.0000005 | FBLIM1/XIRP2/XIRP1/MYLK/LPP/ABLIM3/MICALL2/TRIP6/ZYX/PDLIM2/TEK/BAG3/CRYAB/LCP1/TPM1/CNN2/MYL9/GAS2L1/MYH9/PLS3 | 20 |
| GOBP_POSITIVE_REGULATION_OF_PHAGOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_PHAGOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_PHAGOCYTOSIS | 19/1438 | 71/23056 | 0.2676056 | 4.290623 | 7.162082 | 0.0000000 | 0.0000009 | 0.0000005 | PTPRC/IL1B/IL15/ITGA2/F2RL1/DOCK2/CD36/COLEC10/IL15RA/MBL2/SFTPD/PTPRJ/APOA1/NCKAP1L/MFGE8/C3/SIRPG/SIRPA/IL2RB | 19 |
| GEISS_RESPONSE_TO_DSRNA_UP | GEISS_RESPONSE_TO_DSRNA_UP | GEISS_RESPONSE_TO_DSRNA_UP | 14/1438 | 39/23056 | 0.3589744 | 5.755572 | 7.665932 | 0.0000000 | 0.0000009 | 0.0000006 | GBP1/ELF3/NMI/IQGAP2/TNFAIP3/ANXA1/KLF4/TRAF1/SRGN/CD44/IGFBP6/NFKBIA/TNFAIP2/SAT1 | 14 |
| GOBP_DEFENSE_RESPONSE_TO_SYMBIONT | GOBP_DEFENSE_RESPONSE_TO_SYMBIONT | GOBP_DEFENSE_RESPONSE_TO_SYMBIONT | 44/1438 | 291/23056 | 0.1512027 | 2.424291 | 6.306170 | 0.0000000 | 0.0000009 | 0.0000006 | ZC3H12A/IFI44L/GBP3/GBP1/PTPN22/IFI16/RNASEL/PTPRC/IL1B/RTP4/SPON2/IL15/DDX60/TLR3/F2RL1/STING1/TRIM38/MICA/MICB/TNFAIP3/IL6/TRIM56/IFNE/DDX58/HTRA1/IFITM2/IFITM3/TSPAN32/TRIM5/BIRC3/OASL/IRF9/NLRC5/MLKL/RNF135/SLFN11/SLFN13/DHX58/IL12RB1/MX2/MX1/APOBEC3A/APOBEC3G/APOBEC3H | 44 |
| SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | 55/1438 | 405/23056 | 0.1358025 | 2.177373 | 6.165268 | 0.0000000 | 0.0000009 | 0.0000006 | SYNC/CYP4X1/NEXN/ADCY10/PRRX1/PTGS2/CFH/TGFB2/HNMT/KYNU/TFPI/EPHA4/TMEM158/IGSF10/SUCNR1/FNDC3B/RASSF6/CXCL8/ANXA3/SLC7A11/IL15/FST/ELL2/SNCAIP/SIM1/ARHGAP18/SAMD9L/FOXP2/MEST/PLAT/PLAG1/SULF1/TRPA1/FABP4/MATN2/TNFRSF11B/CD274/PAPPA/PHLDA2/TRIM5/EHF/MMP10/MMP1/HMGA2/TNFRSF19/POSTN/NPAS3/BCL2A1/SOX8/MOCOS/TNFRSF11A/GDF15/PSG5/ADAMTS5/USP18 | 55 |
| WP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION | WP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION | WP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION | 15/1438 | 45/23056 | 0.3333333 | 5.344460 | 7.523650 | 0.0000000 | 0.0000009 | 0.0000006 | S100A10/PTGS2/PLA2G4A/HSD11B1/PPARG/MITF/ANXA3/EDN1/ANXA1/PTGS1/AKR1C3/EDNRB/ANXA2/SOX9/PTGIS | 15 |
| GOBP_POSITIVE_REGULATION_OF_HEMOPOIESIS | GOBP_POSITIVE_REGULATION_OF_HEMOPOIESIS | GOBP_POSITIVE_REGULATION_OF_HEMOPOIESIS | 30/1438 | 159/23056 | 0.1886792 | 3.025166 | 6.608823 | 0.0000000 | 0.0000009 | 0.0000006 | RUNX3/CSF1/PTPRC/ITPKB/NLRP3/CASP8/TGFBR2/BCL6/LEF1/IL15/IL7R/VNN1/GLI3/SHH/ANXA1/IL15RA/NCKAP1L/TESPA1/MMP14/ZFP36L1/FOS/IL4R/TNFSF9/IL12RB1/AXL/TGFB1/IL4I1/RUNX1/LIF/LGALS1 | 30 |
| GOBP_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | GOBP_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | GOBP_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | 37/1438 | 223/23056 | 0.1659193 | 2.660247 | 6.425366 | 0.0000000 | 0.0000009 | 0.0000006 | PTPN22/PTPRC/IL1A/ACKR3/FGFR3/KDR/NPNT/PDGFC/F2RL1/FGF18/TPBG/CCN2/PDGFA/GPNMB/BMPER/CCL26/CD36/FGF20/ANGPT1/TEK/NOTCH1/NRP1/FGFR2/CD44/OR2AT4/IGF1/BMP4/TNFAIP8L3/CCL5/CCR7/TNFRSF11A/ICAM1/TGFB1/APOE/C5AR1/BMP2/PDGFB | 37 |
| WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY | WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY | WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY | 24/1438 | 109/23056 | 0.2201835 | 3.530285 | 6.829266 | 0.0000000 | 0.0000009 | 0.0000006 | CFH/TGFB2/CASP10/CASP8/PLSCR4/CFI/C9/CLU/COLEC10/CRB2/MBL2/FAS/C1S/C1R/C3AR1/MFGE8/LLGL2/COLEC12/MBP/ATP8B3/C3/AXL/TGFB1/C5AR1 | 24 |
| BIOCARTA_ERYTH_PATHWAY | BIOCARTA_ERYTH_PATHWAY | BIOCARTA_ERYTH_PATHWAY | 9/1438 | 15/23056 | 0.6000000 | 9.620028 | 8.613068 | 0.0000000 | 0.0000010 | 0.0000006 | TGFB2/IL1A/CSF2/IL6/IGF1/FLT3/CSF3/TGFB1/IL11 | 9 |
| CHICAS_RB1_TARGETS_GROWING | CHICAS_RB1_TARGETS_GROWING | CHICAS_RB1_TARGETS_GROWING | 39/1438 | 243/23056 | 0.1604938 | 2.573259 | 6.358670 | 0.0000001 | 0.0000010 | 0.0000006 | OLFML3/IFI16/NIBAN1/NMI/FAP/COL3A1/CCDC80/MYLK/LRRC15/SLIT2/ANXA3/GASK1B/ADAMTS6/ADAMTS2/CRYBG1/ADGRG6/CAV1/MEST/PTN/CLU/SULF1/MATN2/HAS2/S1PR3/NRP1/C1R/LUM/POSTN/PYGL/LTBP2/CA12/ANPEP/NUPR1/SLFN11/CAVIN1/SLC14A1/AXL/PSG5/BGN | 39 |
| GOBP_NEGATIVE_REGULATION_OF_LOCOMOTION | GOBP_NEGATIVE_REGULATION_OF_LOCOMOTION | GOBP_NEGATIVE_REGULATION_OF_LOCOMOTION | 54/1438 | 396/23056 | 0.1363636 | 2.186370 | 6.141749 | 0.0000001 | 0.0000010 | 0.0000007 | TIE1/PODN/ATP2B4/BMP10/DPP4/COL3A1/EPHA4/SP100/PPARG/SEMA3B/WNT5A/MITF/PHLDB2/SLIT2/SEMA5A/ADTRP/GJA1/PTPRK/CITED2/HOXA7/SEMA3C/SEMA3A/SEMA3D/SERPINE1/SHH/STC1/SULF1/EPPK1/KLF4/NOTCH1/NRP1/VCL/MMRN2/PTPRJ/KLRC4-KLRK1/ARHGDIB/NAV3/THBS1/CYP19A1/TPM1/MYOCD/JUP/NOG/EMILIN2/ELANE/CNN2/SEMA6B/IL27RA/TGFB1/APOE/RRAS/HAS1/HMOX1/CARD10 | 54 |
| CORRE_MULTIPLE_MYELOMA_UP | CORRE_MULTIPLE_MYELOMA_UP | CORRE_MULTIPLE_MYELOMA_UP | 20/1438 | 79/23056 | 0.2531646 | 4.059083 | 7.024452 | 0.0000001 | 0.0000010 | 0.0000007 | IL1B/DPP4/TFPI/AADAC/VEPH1/ADAMTS12/ITGA2/SLC22A23/SERPINE1/PDGFRL/CSGALNACT1/PLAT/COL13A1/ANKRD1/ALDH1A3/ABCA6/GATA6/SERPINB2/GDF15/PTGIS | 20 |
| HP_HYPERKERATOSIS | HP_HYPERKERATOSIS | HP_HYPERKERATOSIS | 40/1438 | 253/23056 | 0.1581028 | 2.534922 | 6.331473 | 0.0000001 | 0.0000010 | 0.0000007 | TNFRSF1B/FUCA1/NEXN/ECM1/LAMC2/LAMB3/DES/COL6A3/IL17RC/COL7A1/TNNC1/SLCO2A1/VEGFC/ADAMTS2/DSP/CAP2/COL12A1/LAMA4/GJA1/PERP/SASH1/COL14A1/DDX58/MYPN/VCL/ANKRD1/BAG3/FGFR2/CRYAB/ACTC1/TPM1/KRT13/KRT17/JUP/ITGB4/RHBDF2/DSG2/SERPINB7/SERPINB8/COL6A2 | 40 |
| GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS | 22/1438 | 94/23056 | 0.2340426 | 3.752493 | 6.896672 | 0.0000001 | 0.0000010 | 0.0000007 | EDN2/CSF1/WNT5A/CXCL8/VEGFC/F2RL1/EDN1/GPSM3/PLA2G7/IL6/SERPINE1/PTN/RARRES2/C3AR1/NCKAP1L/THBS1/CCL5/CCR7/TNFSF14/C5AR1/DEFB124/RAC2 | 22 |
| LEE_LIVER_CANCER_ACOX1_DN | LEE_LIVER_CANCER_ACOX1_DN | LEE_LIVER_CANCER_ACOX1_DN | 18/1438 | 65/23056 | 0.2769231 | 4.440013 | 7.162952 | 0.0000001 | 0.0000011 | 0.0000007 | HSD11B1/DPP4/IL1RAP/TDO2/LECT2/GPR37/CA3/TPM2/MBL2/SFTPD/PPP1R3C/CYP26A1/SLCO2B1/PHLDA1/HPD/SERPINA1/MYH1/ELANE | 18 |
| MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3 | MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3 | MIKKELSEN_IPS_ICP_WITH_H3K4ME3_AND_H327ME3 | 26/1438 | 126/23056 | 0.2063492 | 3.308475 | 6.701356 | 0.0000001 | 0.0000011 | 0.0000007 | EDN2/CRABP2/BRINP3/COL7A1/CXCL2/ADAMTS16/HLA-E/LAMA4/PTN/ERICH5/PTGS1/DKK1/FIBIN/CD44/PAMR1/OPCML/SCNN1A/HCAR1/SLFN5/HOXB13/ABCC3/KCNJ2/CNN1/FXYD5/ADAM33/FOXS1 | 26 |
| GOBP_POSITIVE_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | GOBP_POSITIVE_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | GOBP_POSITIVE_REGULATION_OF_ANIMAL_ORGAN_MORPHOGENESIS | 13/1438 | 34/23056 | 0.3823529 | 6.130410 | 7.721012 | 0.0000001 | 0.0000011 | 0.0000007 | CSF1/CD34/WNT5A/GDNF/EDN1/DKK1/BMP4/SIX1/SIX4/SOX8/SOX9/BMP2/GATA5 | 13 |
| GOBP_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | GOBP_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | GOBP_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | 38/1438 | 234/23056 | 0.1623932 | 2.603711 | 6.359332 | 0.0000001 | 0.0000011 | 0.0000007 | EDN2/S1PR1/CSF1/CRABP2/ITGA4/NRP2/FN1/TGFBR2/LAMB2/SEMA3B/WNT5A/OSTN/SLIT2/SPP1/SEMA5A/EDN1/DDR1/SEMA3C/SEMA3A/SEMA3D/SHH/EXT1/NOTCH1/NRP1/VCL/FGFR2/YAP1/BMP4/SIX1/SIX4/SALL1/TRPV2/LHX1/SOX9/SEMA6B/MAG/APOE/WNT7B | 38 |
| GOMF_ACTIN_BINDING | GOMF_ACTIN_BINDING | GOMF_ACTIN_BINDING | 58/1438 | 440/23056 | 0.1318182 | 2.113491 | 6.082182 | 0.0000001 | 0.0000011 | 0.0000007 | NEXN/GBP1/LMOD1/CAPG/XIRP2/MLPH/XIRP1/TNNC1/MYLK/MYOZ2/MYO10/RAI14/IQGAP2/ABLIM3/CAP2/UTRN/MICALL2/SCIN/WIPF3/LMOD2/FLNC/PDLIM2/ADCY8/TPM2/GSN/AIF1L/ANXA8/MYPN/MYOZ1/SYNPO2L/VCL/EPS8L2/MICAL2/TAGLN/EPS8/LCP1/AJUBA/MYO1E/TPM1/COTL1/MYH13/MYH8/MYH4/MYH1/MYH2/FMNL1/MYL4/MYOM1/CNN2/CNN1/FXYD5/GMFG/GAS2L1/MYH9/MSN/KLHL4/PLS3/ZNF185 | 58 |
| GOBP_REGULATION_OF_BIOMINERALIZATION | GOBP_REGULATION_OF_BIOMINERALIZATION | GOBP_REGULATION_OF_BIOMINERALIZATION | 23/1438 | 102/23056 | 0.2254902 | 3.615370 | 6.827446 | 0.0000001 | 0.0000011 | 0.0000007 | CCN1/S1PR1/ECM1/OSR1/AMTN/ENAM/SGMS2/ADRB2/BMP6/TFAP2A/TENT5A/GJA1/FAM20C/PTN/NOTCH1/ALOX5/SRGN/WNT10B/BMP4/SOX9/TGFB1/BMP2/CEBPB | 23 |
| GOBP_MUSCLE_ADAPTATION | GOBP_MUSCLE_ADAPTATION | GOBP_MUSCLE_ADAPTATION | 25/1438 | 118/23056 | 0.2118644 | 3.396902 | 6.732368 | 0.0000001 | 0.0000011 | 0.0000007 | ERRFI1/TNFRSF1B/TRIM63/CASQ1/ATP2B4/AGT/BMP10/IL1B/PPARG/TNNC1/MYOZ2/TRPC3/IL15/EDN1/FBXO32/GSN/NOTCH1/MYOZ1/TNFRSF1A/IGF1/FOXO1/SGCA/GATA6/GATA5/HMOX1 | 25 |
| GOBP_MAMMARY_GLAND_DEVELOPMENT | GOBP_MAMMARY_GLAND_DEVELOPMENT | GOBP_MAMMARY_GLAND_DEVELOPMENT | 27/1438 | 135/23056 | 0.2000000 | 3.206676 | 6.631976 | 0.0000001 | 0.0000012 | 0.0000008 | EPHA2/CSF1/ELF3/LBH/TGFA/TGFBR2/WNT5A/LEF1/EGF/ITGA2/RREB1/DDR1/GJA1/GLI3/CAV1/ZNF703/FGFR2/PGR/STAT6/BMP4/CYP19A1/FOXB1/FOXF1/SOX9/TNFRSF11A/CEBPB/WNT7B | 27 |
| WANG_TNF_TARGETS | WANG_TNF_TARGETS | WANG_TNF_TARGETS | 11/1438 | 24/23056 | 0.4583333 | 7.348632 | 8.025539 | 0.0000001 | 0.0000012 | 0.0000008 | VCAM1/CSF2/TNFAIP3/IL6/TRAF1/MMP3/NFKBIA/CD68/CCL5/CSF3/GDF15 | 11 |
| SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | 55/1438 | 409/23056 | 0.1344743 | 2.156078 | 6.084119 | 0.0000001 | 0.0000012 | 0.0000008 | PRRX1/RAB7B/IL1R1/GYPC/LYPD6B/ITGA4/NRP2/TGFBR2/COL8A1/CCDC80/SPON2/SLIT2/BMP3/PCDH10/DAB2/EDIL3/CHSY3/TGFBI/FGF18/ID4/TENT5A/AHR/AQP1/INHBA/SULF1/SLC26A7/MATN2/RSPO2/COLEC10/GAS1/PAPPA/TCERG1L/FIBIN/PAMR1/SLCO2B1/ARHGAP42/MMP10/MMP3/UBASH3B/ADAMTS8/IGF1/NUAK1/LRFN5/ZFP36L1/THBS1/BMF/LOXL1/ANPEP/ADAMTS18/KRT17/SLC16A3/SLC14A1/SLC7A10/RUNX1/DACH2 | 55 |
| REACTOME_TNFS_BIND_THEIR_PHYSIOLOGICAL_RECEPTORS | REACTOME_TNFS_BIND_THEIR_PHYSIOLOGICAL_RECEPTORS | REACTOME_TNFS_BIND_THEIR_PHYSIOLOGICAL_RECEPTORS | 12/1438 | 29/23056 | 0.4137931 | 6.634502 | 7.830511 | 0.0000001 | 0.0000012 | 0.0000008 | TNFRSF18/TNFRSF4/TNFRSF9/TNFRSF1B/TNFSF18/TNFRSF11B/TNFSF15/TNFRSF1A/TNFSF13B/TNFSF9/CD70/TNFSF14 | 12 |
| GOBP_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS | GOBP_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS | GOBP_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS | 15/1438 | 46/23056 | 0.3260870 | 5.228276 | 7.403519 | 0.0000001 | 0.0000012 | 0.0000008 | TBX15/PRRX1/DLX2/TGFBR2/TFAP2A/RUNX2/HOXA1/HOXA2/GLI3/FGFR2/MMP14/BMP4/SIX1/SIX4/LHX1 | 15 |
| GOBP_NEGATIVE_REGULATION_OF_GROWTH | GOBP_NEGATIVE_REGULATION_OF_GROWTH | GOBP_NEGATIVE_REGULATION_OF_GROWTH | 39/1438 | 245/23056 | 0.1591837 | 2.552252 | 6.299810 | 0.0000001 | 0.0000012 | 0.0000008 | CDA/TGFB2/AGT/BMP10/SERPINE2/TGFBR2/SEMA3B/WNT5A/BCL6/OSTN/FGFR3/SLIT2/PLAC8/SPP1/SEMA5A/DAB2/ADRB2/GJA1/CITED2/INHBA/SEMA3C/SEMA3A/SEMA3D/NRP1/MYOZ1/TLL2/WT1/PTPRJ/CRYAB/BMP4/BDKRB1/MT2A/MT1X/OSGIN1/NOG/SEMA6B/GDF15/MAG/TGFB1 | 39 |
| HP_ARTHRITIS | HP_ARTHRITIS | HP_ARTHRITIS | 35/1438 | 207/23056 | 0.1690821 | 2.710958 | 6.377422 | 0.0000001 | 0.0000013 | 0.0000008 | PTPN22/HJV/FCGR2A/PRG4/NLRP3/COL3A1/COL5A2/CASP10/SLCO2A1/FGFR3/SPP1/CFI/RREB1/HFE/HLA-C/PSMB9/TENT5A/CCN2/IL6/CAV1/TRPS1/EXT1/TNFRSF11B/COL5A1/FAS/FGFR2/TNFRSF1A/MMP14/EPB42/FBN1/MMP2/COL1A1/APOE/COL9A3/IL2RB | 35 |
| GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | 22/1438 | 95/23056 | 0.2315789 | 3.712993 | 6.833912 | 0.0000001 | 0.0000013 | 0.0000008 | TGFB2/RASGRP3/ITGB5/SOD3/AHRR/HLA-E/COL19A1/TENT5A/MACC1/UPK3B/SEMA3C/SEMA3D/COLEC10/LRATD2/EPPK1/LOXL4/SLC22A18/PHLDA2/LCP1/KLF2/CSDC2/WNT7B | 22 |
| LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | 37/1438 | 226/23056 | 0.1637168 | 2.624934 | 6.331275 | 0.0000001 | 0.0000013 | 0.0000008 | IFI16/LAMB3/NPAS2/HNMT/COL7A1/FGFR3/ITGA2/GPSM3/NT5E/ROS1/ADGRG6/GLI3/TRIP6/EPHB6/EXT1/COL27A1/NOTCH1/PYROXD2/PTPRE/CD44/AHNAK/SYTL2/CASP4/CASP1/MPZL2/VWA5A/AJUBA/FRMD6/SMAD6/LPCAT2/KRT17/CNN2/GMFG/CYP24A1/MXRA5/COL4A6/COL4A5 | 37 |
| BURTON_ADIPOGENESIS_8 | BURTON_ADIPOGENESIS_8 | BURTON_ADIPOGENESIS_8 | 20/1438 | 80/23056 | 0.2500000 | 4.008345 | 6.951678 | 0.0000001 | 0.0000013 | 0.0000008 | VCAM1/CAPG/TWIST2/PHLDB2/ANXA3/TAPBP/PLA2G7/TPBG/VCL/PRSS23/EMP1/SLC38A4/SMAD6/FXYD5/EMP3/PTGIS/MYH9/KDELR3/MSN/COL4A5 | 20 |
| GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP | GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP | GRAHAM_CML_QUIESCENT_VS_NORMAL_DIVIDING_UP | 17/1438 | 59/23056 | 0.2881356 | 4.619787 | 7.180054 | 0.0000001 | 0.0000013 | 0.0000008 | GBP1/PTGS2/IL1B/CXCL8/CXCL6/CXCL5/CXCL2/RHAG/SOD2/INHBA/CA1/TCF7L2/CCL5/SERPINB2/GADD45B/BCL3/APOE | 17 |
| WP_COMPLEMENT_AND_COAGULATION_CASCADES | WP_COMPLEMENT_AND_COAGULATION_CASCADES | WP_COMPLEMENT_AND_COAGULATION_CASCADES | 17/1438 | 59/23056 | 0.2881356 | 4.619787 | 7.180054 | 0.0000001 | 0.0000013 | 0.0000008 | CFH/TFPI/CFI/C9/SERPINE1/CLU/PLAT/PLAU/VWF/C1S/C1R/C3AR1/SERPINA1/BDKRB1/C3/C5AR1/THBD | 17 |
| GOBP_EMBRYONIC_APPENDAGE_MORPHOGENESIS | GOBP_EMBRYONIC_APPENDAGE_MORPHOGENESIS | GOBP_EMBRYONIC_APPENDAGE_MORPHOGENESIS | 25/1438 | 119/23056 | 0.2100840 | 3.368357 | 6.680464 | 0.0000001 | 0.0000013 | 0.0000008 | ECE1/CRABP2/PRRX1/TGFB2/OSR1/CYP26B1/SP9/RARB/WNT5A/LEF1/TFAP2A/RUNX2/GJA1/GLI3/SHH/FZD6/RSPO2/NOTCH1/DKK1/ALX4/FREM2/BMP4/ALDH1A2/SALL1/NOG | 25 |
| NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | 43/1438 | 285/23056 | 0.1508772 | 2.419071 | 6.217129 | 0.0000001 | 0.0000013 | 0.0000008 | FBLIM1/LAMC2/NIBAN1/LTBP1/CRIM1/EFEMP1/GPR39/ITGB6/COL3A1/FN1/CCDC80/ITGB5/ANXA3/IL7R/FST/F2RL1/TGFBI/ADAM19/COL12A1/LAMA4/PTPRK/INHBA/CAV2/CAV1/PODXL/LY6K/VCL/MYEOV/PRSS23/EMP1/AMIGO2/KRT7/HMGA2/GLIPR1/LATS2/NID2/THBS1/TPM1/MMP2/KIFC3/AXL/NFATC2/MYH9 | 43 |
| GOBP_SEGMENTATION | GOBP_SEGMENTATION | GOBP_SEGMENTATION | 23/1438 | 103/23056 | 0.2233010 | 3.580269 | 6.768901 | 0.0000001 | 0.0000013 | 0.0000008 | OSR1/NRP2/WNT5A/LEF1/IRX2/FOXC1/TDRD6/TBX18/HOXA2/SEMA3C/SEMA3A/DMRT2/CRB2/NOTCH1/NRP1/DKK1/WT1/BMP4/ALDH1A2/FOXB1/FOXF1/LHX1/MEOX1 | 23 |
| HOSHIDA_LIVER_CANCER_SURVIVAL_UP | HOSHIDA_LIVER_CANCER_SURVIVAL_UP | HOSHIDA_LIVER_CANCER_SURVIVAL_UP | 19/1438 | 73/23056 | 0.2602740 | 4.173071 | 7.003130 | 0.0000001 | 0.0000013 | 0.0000008 | EPHA4/SP100/COL6A3/LPP/ANXA3/EGF/DAB2/IER3/DDR1/PSMB9/PODXL/LOXL2/ANXA1/NFKB2/KRT7/IGFBP6/FBN1/SERPINB2/SERPINB8 | 19 |
| LINDVALL_IMMORTALIZED_BY_TERT_DN | LINDVALL_IMMORTALIZED_BY_TERT_DN | LINDVALL_IMMORTALIZED_BY_TERT_DN | 19/1438 | 73/23056 | 0.2602740 | 4.173071 | 7.003130 | 0.0000001 | 0.0000013 | 0.0000008 | HSPG2/CCN1/FAP/FN1/CCDC80/ITGB5/LRRC15/CXCL1/MDFI/LAMA4/FBXO32/PAPPA/ADM/LRRC32/NNMT/SELPLG/LTBP2/CRIP1/SAT1 | 19 |
| GOBP_SPROUTING_ANGIOGENESIS | GOBP_SPROUTING_ANGIOGENESIS | GOBP_SPROUTING_ANGIOGENESIS | 33/1438 | 189/23056 | 0.1746032 | 2.799479 | 6.406596 | 0.0000001 | 0.0000013 | 0.0000009 | EPHA2/PTGS2/SLIT2/KDR/LEF1/VEGFC/SEMA5A/PLK2/FGF18/ADTRP/RSPO3/BMPER/EPHB4/LOXL2/ANGPT1/TEK/CEMIP2/ANXA1/KLF4/NOTCH1/JCAD/NRP1/ALOX5/MMRN2/CREB3L1/ITGA5/BMP4/THBS1/CDH13/KLF2/HMOX1/CARD10/SRPX2 | 33 |
| LEE_LIVER_CANCER_CIPROFIBRATE_DN | LEE_LIVER_CANCER_CIPROFIBRATE_DN | LEE_LIVER_CANCER_CIPROFIBRATE_DN | 18/1438 | 66/23056 | 0.2727273 | 4.372740 | 7.076843 | 0.0000001 | 0.0000013 | 0.0000009 | HSD11B1/KYNU/DPP4/BCL6/IL1RAP/LECT2/GPR37/CA3/MBL2/PPP1R3C/CYP26A1/WNT10B/KRT4/HPD/SERPINA6/TRPV2/KRT13/ELANE | 18 |
| REACTOME_DISEASES_OF_METABOLISM | REACTOME_DISEASES_OF_METABOLISM | REACTOME_DISEASES_OF_METABOLISM | 39/1438 | 246/23056 | 0.1585366 | 2.541877 | 6.270598 | 0.0000001 | 0.0000013 | 0.0000009 | AGRN/HSPG2/ADAMTSL4/FMO3/PRELP/CYP26B1/LCT/GALNT3/MUC13/SPON2/SLC34A2/ADAMTS3/ADAMTS16/SEMA5A/ADAMTS12/ADAMTS6/ADAMTS2/THBS2/EXT1/B4GALT1/NOTCH1/SFTPD/PAPSS2/PPP1R3C/ADAMTS8/ADAMTS15/LUM/THBS1/CYP19A1/CSPG4/ADAMTS18/ADAMTSL5/MUC16/SDC4/CYP24A1/ADAMTS5/GGT1/GPC4/BGN | 39 |
| GOBP_CELL_FATE_COMMITMENT | GOBP_CELL_FATE_COMMITMENT | GOBP_CELL_FATE_COMMITMENT | 41/1438 | 266/23056 | 0.1541353 | 2.471310 | 6.224826 | 0.0000001 | 0.0000014 | 0.0000009 | PTCH2/TBX15/PRRX1/WNT9A/CYP26B1/DLX1/DLX2/PPARG/WNT5A/MITF/HES1/KDR/EDN1/RUNX2/GCM1/TBX18/IL6/HOXA2/GLI3/SHH/EBF2/EXT1/GAS1/KLF4/NOTCH1/NRP1/DKK1/TCF7L2/FGFR2/WT1/WNT10B/STAT6/BMP4/SIX1/SOX8/SOX9/GATA6/IL12RB1/BMP2/GATA5/WNT7B | 41 |
| WP_OVERVIEW_OF_PROINFLAMMATORY_AND_PROFIBROTIC_MEDIATORS | WP_OVERVIEW_OF_PROINFLAMMATORY_AND_PROFIBROTIC_MEDIATORS | WP_OVERVIEW_OF_PROINFLAMMATORY_AND_PROFIBROTIC_MEDIATORS | 26/1438 | 128/23056 | 0.2031250 | 3.256780 | 6.603367 | 0.0000001 | 0.0000014 | 0.0000009 | CSF1/IL1A/IL1B/IL36G/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/SPP1/IL15/TSLP/CSF2/IL6/CCL26/MMP1/MMP3/TNFSF13B/CTF1/CCL5/CSF3/EBI3/TGFB1/IL11/LIF | 26 |
| GOBP_ACTOMYOSIN_STRUCTURE_ORGANIZATION | GOBP_ACTOMYOSIN_STRUCTURE_ORGANIZATION | GOBP_ACTOMYOSIN_STRUCTURE_ORGANIZATION | 34/1438 | 199/23056 | 0.1708543 | 2.739371 | 6.355702 | 0.0000001 | 0.0000014 | 0.0000009 | S1PR1/RHOC/S100A10/CASQ1/LMOD1/BMP10/PHLDB2/ITGB5/MYOZ2/EDN1/CCN2/MET/LMOD2/FLNC/ZYX/ARHGEF5/NRP1/MYPN/MYOZ1/SYNPO2L/ANKRD1/APOA1/FRMD6/SIX4/ACTC1/CGNL1/TPM1/MYLK3/KRT19/CNN2/CNN1/MYL9/SDC4/MYH9 | 34 |
| HALLMARK_IL2_STAT5_SIGNALING | HALLMARK_IL2_STAT5_SIGNALING | HALLMARK_IL2_STAT5_SIGNALING | 34/1438 | 199/23056 | 0.1708543 | 2.739371 | 6.355702 | 0.0000001 | 0.0000014 | 0.0000009 | TNFRSF18/TNFRSF4/TNFRSF9/TNFRSF1B/DHRS3/GBP4/CSF1/ECM1/CAPG/ITGA6/BHLHE40/CDCP1/SPP1/CSF2/ADAM19/TNFRSF21/NT5E/AHR/TRAF1/MAP3K8/NRP1/IFITM3/CD44/AHNAK/EMP1/PHLDA1/MYO1E/IL4R/GADD45B/PRNP/BMP2/TGM2/LIF/IL2RB | 34 |
| GOBP_POSITIVE_REGULATION_OF_BIOMINERALIZATION | GOBP_POSITIVE_REGULATION_OF_BIOMINERALIZATION | GOBP_POSITIVE_REGULATION_OF_BIOMINERALIZATION | 16/1438 | 53/23056 | 0.3018868 | 4.840266 | 7.218737 | 0.0000001 | 0.0000015 | 0.0000009 | CCN1/OSR1/AMTN/ENAM/ADRB2/BMP6/TFAP2A/TENT5A/FAM20C/PTN/ALOX5/WNT10B/BMP4/TGFB1/BMP2/CEBPB | 16 |
| GOBP_NEURAL_CREST_CELL_DIFFERENTIATION | GOBP_NEURAL_CREST_CELL_DIFFERENTIATION | GOBP_NEURAL_CREST_CELL_DIFFERENTIATION | 22/1438 | 96/23056 | 0.2291667 | 3.674316 | 6.771996 | 0.0000001 | 0.0000015 | 0.0000010 | NRP2/FN1/SEMA3B/HES1/SEMA5A/GDNF/FOXC1/EDN1/CITED2/SEMA3C/SEMA3A/SEMA3D/SHH/EXT1/NRP1/EDNRB/BMP4/SIX1/ALDH1A2/SOX8/SOX9/SEMA6B | 22 |
| GOBP_REGULATION_OF_CELL_DEVELOPMENT | GOBP_REGULATION_OF_CELL_DEVELOPMENT | GOBP_REGULATION_OF_CELL_DEVELOPMENT | 63/1438 | 500/23056 | 0.1260000 | 2.020206 | 5.948343 | 0.0000001 | 0.0000015 | 0.0000010 | TNFRSF1B/GBP1/S100A10/CRABP2/IL1A/IL1B/DLX1/DLX2/FN1/EPHA4/SERPINE2/BHLHE40/SEMA3B/WNT5A/MME/HES1/SLIT2/SPP1/VEGFC/SEMA5A/DAB2/RREB1/ID4/TCP11/IL6/GLI3/SEMA3C/SEMA3A/SEMA3D/PTPRZ1/PTN/SHH/PLAG1/HAS2/S1PR3/PAEP/NOTCH1/NRP1/VCL/PITX3/YAP1/APOA1/TNFRSF1A/BHLHE41/IGF1/EDNRB/NFATC4/BMP4/FBN1/BNC1/SOX8/TRPV2/HAP1/HOXB3/NOG/SIGLEC15/MBP/SEMA6B/MAG/TGFB1/BMP2/TGM2/LIF | 63 |
| GOBP_OUTFLOW_TRACT_MORPHOGENESIS | GOBP_OUTFLOW_TRACT_MORPHOGENESIS | GOBP_OUTFLOW_TRACT_MORPHOGENESIS | 20/1438 | 81/23056 | 0.2469136 | 3.958859 | 6.880077 | 0.0000001 | 0.0000015 | 0.0000010 | DHRS3/TGFB2/NRP2/TGFBR2/WNT5A/HES1/FOXC1/EDN1/CITED2/SEMA3C/FZD1/ZFPM2/NOTCH1/NRP1/FGFR2/BMP4/SIX1/SMAD6/NOG/GATA6 | 20 |
| GOBP_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | GOBP_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | GOBP_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES | 42/1438 | 277/23056 | 0.1516245 | 2.431054 | 6.179919 | 0.0000001 | 0.0000015 | 0.0000010 | NEXN/VCAM1/HMCN1/IGFN1/TGFB2/TGFBR2/CLDN1/CLDN16/IL1RAP/FGFRL1/GRID2/FAT4/PCDH10/CDH9/MDGA1/KLF4/CRB2/MYPN/APOA1/MPZL2/ROBO4/AMIGO2/ITGA5/AJUBA/LRFN5/CLDN6/CDH13/CDH15/CLDN7/PECAM1/MILR1/DSG2/MBP/ICAM1/FXYD5/MAG/NECTIN2/BMP2/GATA5/CELSR1/TENM1/GPC4 | 42 |
| BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP | BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP | BLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP | 27/1438 | 137/23056 | 0.1970803 | 3.159863 | 6.539476 | 0.0000001 | 0.0000015 | 0.0000010 | GBP1/CSF1/DPP4/CLDN16/IL7R/EDIL3/CD109/TNFAIP3/IL6/PLAT/TRAF1/PTGS1/PYGM/BIRC3/C1S/ITGA7/POSTN/IRF9/THBS1/NLRC5/CDYL2/SLFN5/CCL5/DHX58/IFI35/ICAM1/USP18 | 27 |
| MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 | MIKKELSEN_ES_ICP_WITH_H3K4ME3_AND_H3K27ME3 | 27/1438 | 137/23056 | 0.1970803 | 3.159863 | 6.539476 | 0.0000001 | 0.0000015 | 0.0000010 | EDN2/KCNN3/CRABP2/BRINP3/ADAMTS16/HLA-E/LAMA4/GPNMB/PDE1C/MYL7/PTN/IDO1/PTGS1/APBB1IP/DKK1/FIBIN/CD44/PAMR1/OPCML/SCNN1A/IGF1/SLFN5/HOXB13/ABCC3/KCNJ2/FXYD5/ADAM33 | 27 |
| HALLMARK_ALLOGRAFT_REJECTION | HALLMARK_ALLOGRAFT_REJECTION | HALLMARK_ALLOGRAFT_REJECTION | 34/1438 | 200/23056 | 0.1700000 | 2.725674 | 6.321615 | 0.0000001 | 0.0000016 | 0.0000010 | GBP2/CSF1/CTSS/PTPRC/TGFB2/NLRP3/CAPG/IL1B/STAB1/CD96/EREG/IL15/TLR3/HLA-E/TAPBP/IL6/INHBA/MBL2/SRGN/FAS/KLRD1/IL4R/PSMB10/CCL5/ELANE/ICAM1/IL27RA/IL12RB1/TGFB1/BCL3/IL11/ICOSLG/LIF/IL2RB | 34 |
| DAZARD_UV_RESPONSE_CLUSTER_G28 | DAZARD_UV_RESPONSE_CLUSTER_G28 | DAZARD_UV_RESPONSE_CLUSTER_G28 | 10/1438 | 20/23056 | 0.5000000 | 8.016690 | 8.096512 | 0.0000001 | 0.0000016 | 0.0000011 | PTGS2/CXCL8/CXCL3/CXCL2/IER3/CCN2/CITED2/PHLDA2/ANXA2/GADD45B | 10 |
| MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_DN | 10/1438 | 20/23056 | 0.5000000 | 8.016690 | 8.096512 | 0.0000001 | 0.0000016 | 0.0000011 | EFEMP1/ACTG2/ITGB6/NT5E/CCN2/TNS3/AQP3/TAGLN/KRT17/SPANXA1 | 10 |
| GOBP_CELLULAR_RESPONSE_TO_RETINOIC_ACID | GOBP_CELLULAR_RESPONSE_TO_RETINOIC_ACID | GOBP_CELLULAR_RESPONSE_TO_RETINOIC_ACID | 18/1438 | 67/23056 | 0.2686567 | 4.307475 | 6.992431 | 0.0000001 | 0.0000017 | 0.0000011 | BRINP3/WNT9A/OSR1/CYP26B1/WNT5A/EPHA3/HOXA2/AQP1/STRA8/FGFR2/FZD4/YAP1/WNT10B/LTK/ALDH1A2/COL1A1/SOX9/WNT7B | 18 |
| VANHARANTA_UTERINE_FIBROID_DN | VANHARANTA_UTERINE_FIBROID_DN | VANHARANTA_UTERINE_FIBROID_DN | 18/1438 | 67/23056 | 0.2686567 | 4.307475 | 6.992431 | 0.0000001 | 0.0000017 | 0.0000011 | LTBP1/TFPI/ACKR3/BCL6/MOXD1/CITED2/MDFIC/RARRES2/KLF4/MS4A4A/PLAAT4/BIRC3/C1S/C1R/ABCA8/GADD45B/KLF2/APOL3 | 18 |
| GOBP_MESENCHYMAL_CELL_DEVELOPMENT | GOBP_MESENCHYMAL_CELL_DEVELOPMENT | GOBP_MESENCHYMAL_CELL_DEVELOPMENT | 21/1438 | 89/23056 | 0.2359551 | 3.783157 | 6.784765 | 0.0000001 | 0.0000017 | 0.0000011 | NRP2/FN1/SEMA3B/HES1/SEMA5A/GDNF/FOXC1/EDN1/CITED2/SEMA3C/SEMA3A/SEMA3D/SHH/NOTCH1/NRP1/EDNRB/BMP4/ALDH1A2/SOX8/SOX9/SEMA6B | 21 |
| HP_DERMAL_ATROPHY | HP_DERMAL_ATROPHY | HP_DERMAL_ATROPHY | 21/1438 | 89/23056 | 0.2359551 | 3.783157 | 6.784765 | 0.0000001 | 0.0000017 | 0.0000011 | LAMC2/LAMB3/TGFB2/ITGA6/COL3A1/COL5A2/COL6A3/TWIST2/TGFBR2/COL7A1/TFAP2A/COL12A1/GSN/COL5A1/MMP1/C1S/C1R/FBN1/COL1A1/ITGB4/COL6A2 | 21 |
| GOBP_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_REGULATION_OF_DEVELOPMENTAL_GROWTH | 47/1438 | 329/23056 | 0.1428571 | 2.290483 | 6.080417 | 0.0000001 | 0.0000017 | 0.0000011 | AGRN/CSF1/CRABP2/BMP10/FN1/TGFBR2/SEMA3B/WNT5A/OSTN/FGFR3/PLAC8/SPP1/SEMA5A/ADRB2/FOXC1/EDN1/CITED2/SEMA3C/SEMA3A/SEMA3D/FGF20/ZFPM2/EPPK1/SPAAR/NOTCH1/NRP1/MYOZ1/TLL2/FGFR2/WT1/YAP1/YBX3/GLI1/IGF1/LATS2/BMP4/SIX1/SIX4/TRPV2/NOG/GATA6/SEMA6B/GDF15/MAG/APOE/FOXS1/RUNX1 | 47 |
| GOMF_CYTOKINE_RECEPTOR_ACTIVITY | GOMF_CYTOKINE_RECEPTOR_ACTIVITY | GOMF_CYTOKINE_RECEPTOR_ACTIVITY | 22/1438 | 97/23056 | 0.2268041 | 3.636437 | 6.710903 | 0.0000001 | 0.0000018 | 0.0000012 | IL22RA1/IL1R1/ACKR3/IL17RC/ACKR2/CCR3/IL1RAP/IL7R/OSMR/IL31RA/IL15RA/CD44/FZD4/FLT3/IL4R/IL21R/CCR7/EBI3/IL27RA/IL12RB1/IL2RB/IL13RA1 | 22 |
| HP_AMYLOIDOSIS | HP_AMYLOIDOSIS | HP_AMYLOIDOSIS | 12/1438 | 30/23056 | 0.4000000 | 6.413352 | 7.651946 | 0.0000001 | 0.0000018 | 0.0000012 | NLRP3/COL7A1/OSMR/IL31RA/GSN/SAA1/MMP1/APOA1/TNFRSF1A/SLC7A7/APOE/PRNP | 12 |
| HP_ABNORMALITY_OF_UPPER_LIMB_JOINT | HP_ABNORMALITY_OF_UPPER_LIMB_JOINT | HP_ABNORMALITY_OF_UPPER_LIMB_JOINT | 62/1438 | 492/23056 | 0.1260163 | 2.020466 | 5.901026 | 0.0000001 | 0.0000019 | 0.0000012 | MMP23B/ECE1/HSPG2/PTPN22/TBX15/LAMC2/PRG4/LAMB3/NLRP3/CYP26B1/ACTG2/COL5A2/COL6A3/TWIST2/TGFBR2/COL7A1/LAMB2/WNT5A/CD96/FGFRL1/FGFR3/DOK7/SLC34A2/ADAMTS3/FAT4/TFAP2A/PSMB8/COL12A1/TENT5A/GJA1/LAMA2/CCN2/GLI3/TMEM270/CAV1/SHH/CSGALNACT1/TRPS1/EXT1/COLEC10/TPM2/COL27A1/COL5A1/FGFR2/ITGA7/GLI1/MMP14/BMP4/FBN1/SMAD6/MMP2/MAF/COL1A1/NOG/ITGB4/PIEZO2/RRAS/COL9A3/COL6A2/IL2RB/GPC4/BGN | 62 |
| DASU_IL6_SIGNALING_SCAR_DN | DASU_IL6_SIGNALING_SCAR_DN | DASU_IL6_SIGNALING_SCAR_DN | 9/1438 | 16/23056 | 0.5625000 | 9.018776 | 8.275249 | 0.0000001 | 0.0000019 | 0.0000012 | CCN1/CCN2/SERPINE1/LOXL2/SULF1/PPP1R3C/THBS1/TPM1/HMOX1 | 9 |
| LENAOUR_DENDRITIC_CELL_MATURATION_DN | LENAOUR_DENDRITIC_CELL_MATURATION_DN | LENAOUR_DENDRITIC_CELL_MATURATION_DN | 26/1438 | 130/23056 | 0.2000000 | 3.206676 | 6.507293 | 0.0000001 | 0.0000019 | 0.0000012 | TNFRSF1B/FCGR2A/IL1B/KYNU/STAB1/CXCL8/CXCL5/CXCL3/CXCL2/IER3/MICB/SOD2/HTRA1/CD44/C3AR1/EMP1/ARHGDIB/NFKBIA/SERPINA1/ANPEP/CES1/C3/C5AR1/EMP3/CD37/LGALS2 | 26 |
| GOBP_REGULATION_OF_BLOOD_PRESSURE | GOBP_REGULATION_OF_BLOOD_PRESSURE | GOBP_REGULATION_OF_BLOOD_PRESSURE | 32/1438 | 183/23056 | 0.1748634 | 2.803651 | 6.317871 | 0.0000001 | 0.0000019 | 0.0000012 | ECE1/EDN2/PTGS2/CD34/AGT/PPARG/SUCNR1/VEGFC/ADAMTS16/NPR3/F2RL1/ERAP2/LVRN/ADRB2/EDN1/SOD2/EXT1/PCSK5/PTGS1/RNLS/ADM/ARHGAP42/SPX/EDNRB/BDKRB1/TPM1/ANPEP/ACSM3/KCNK6/ADRA1D/HMOX1/PDGFB | 32 |
| BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | 35/1438 | 211/23056 | 0.1658768 | 2.659565 | 6.245889 | 0.0000001 | 0.0000019 | 0.0000012 | DHRS3/PADI3/OLFML3/SH2D2A/LONRF2/MLPH/BHLHE40/SEMA3B/FGFRL1/DOK7/FOXC1/TPD52L1/UST/ZNF703/B4GALT1/NXNL2/PHLDA2/MYEOV/P2RY2/PRSS23/PGR/VWF/SCNN1A/CA12/SOX8/OSGIN1/SLC47A1/KRT15/ADAMTSL5/CYP4F11/MAG/KCNK6/TGM2/A4GALT/ZNF185 | 35 |
| BROWN_MYELOID_CELL_DEVELOPMENT_UP | BROWN_MYELOID_CELL_DEVELOPMENT_UP | BROWN_MYELOID_CELL_DEVELOPMENT_UP | 30/1438 | 165/23056 | 0.1818182 | 2.915160 | 6.367499 | 0.0000001 | 0.0000020 | 0.0000013 | CTSS/S100A11/FCGR2A/CAPG/IL1B/SP100/CLDN1/EREG/SGMS2/DAB2/EDIL3/TGFBI/ZYX/CEBPD/GSN/CD44/SLC15A3/TNFRSF1A/PYGL/BCL2A1/ANPEP/NQO1/CD68/CNN2/C3/IL4I1/FPR1/SIRPA/APOL3/SAT1 | 30 |
| VECCHI_GASTRIC_CANCER_EARLY_DN | VECCHI_GASTRIC_CANCER_EARLY_DN | VECCHI_GASTRIC_CANCER_EARLY_DN | 52/1438 | 384/23056 | 0.1354167 | 2.171187 | 5.968994 | 0.0000001 | 0.0000021 | 0.0000013 | CFH/EFEMP1/LONRF2/CYBRD1/CAVIN2/DNER/AADAC/VEPH1/SLIT2/SULT1E1/JCHAIN/ARHGAP24/PDGFC/IRX2/ELL2/MZB1/ADRB2/ADTRP/GMPR/ID4/RCAN2/LAMA2/SMLR1/CITED2/WIPF3/CD36/PDK4/MDFIC/PTPRZ1/CPA2/CLU/PNOC/FABP4/SLC26A7/ANGPT1/GAS1/RNLS/APOC3/APOA1/CGNL1/ALDH1A2/RBPMS2/MT1X/MAF/CCL5/GIP/ABCA8/GADD45B/CNN1/GATA5/ITM2A/COL4A6 | 52 |
| GOBP_RESPONSE_TO_INTERFERON_GAMMA | GOBP_RESPONSE_TO_INTERFERON_GAMMA | GOBP_RESPONSE_TO_INTERFERON_GAMMA | 27/1438 | 139/23056 | 0.1942446 | 3.114397 | 6.448659 | 0.0000001 | 0.0000021 | 0.0000013 | GBP3/GBP1/GBP2/GBP4/GBP5/RAB7B/KYNU/NMI/SP100/PPARG/WNT5A/PARP14/CLDN1/TXK/TLR3/EDN1/CCL26/ZYX/GSN/IFITM2/IFITM3/CASP1/RAB20/NLRC5/CCL5/IL12RB1/SIRPA | 27 |
| GOBP_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS | GOBP_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS | GOBP_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS | 37/1438 | 231/23056 | 0.1601732 | 2.568117 | 6.177793 | 0.0000001 | 0.0000021 | 0.0000014 | TGFB2/OSR1/SRD5A2/IL1A/WNT5A/FOXL2/SLIT2/KDR/EREG/TLR3/FST/FOXC1/GJA1/CITED2/PDGFA/INHBA/SEMA3A/ZFPM2/DMRTA1/AKR1C3/WT1/FZD4/PGR/YBX3/MMP14/SIX4/CYP19A1/SOX8/NUPR1/SALL1/MMP2/SOX9/GATA6/CEBPB/TFAP2C/COL9A3/DACH2 | 37 |
| FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS | FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS | FISCHER_DIRECT_P53_TARGETS_META_ANALYSIS | 45/1438 | 311/23056 | 0.1446945 | 2.319942 | 6.044306 | 0.0000001 | 0.0000021 | 0.0000014 | DHRS3/EPHA2/SYNC/EDN2/CSF1/S100A2/CAVIN2/BHLHE40/COL7A1/SEMA3B/BCL6/HES1/GASK1B/TLR3/PLK2/RNF144B/IER3/DDR1/PTP4A1/TRIP6/SERPINE1/TNFRSF10C/TNFRSF10A/LRATD2/FAS/PPP1R3C/EPS8L2/CD82/ARHGAP42/YAP1/BCL9L/KRT8/DRAM1/MFGE8/ALDH1A3/NUPR1/ORAI3/RRAD/KRT15/ITGA3/GDF15/KCNN4/ICOSLG/LIF/APOBEC3H | 45 |
| DAUER_STAT3_TARGETS_UP | DAUER_STAT3_TARGETS_UP | DAUER_STAT3_TARGETS_UP | 15/1438 | 48/23056 | 0.3125000 | 5.010431 | 7.173424 | 0.0000001 | 0.0000022 | 0.0000014 | AGT/HEG1/BCL6/GFPT2/SOD2/CEBPD/ADM/FOSL1/SLC2A14/THBS1/SOCS3/C3/ICAM1/ZFP36/BCL3 | 15 |
| GOMF_IMMUNE_RECEPTOR_ACTIVITY | GOMF_IMMUNE_RECEPTOR_ACTIVITY | GOMF_IMMUNE_RECEPTOR_ACTIVITY | 28/1438 | 148/23056 | 0.1891892 | 3.033342 | 6.400324 | 0.0000001 | 0.0000022 | 0.0000014 | IL22RA1/MR1/IL1R1/ACKR3/IL17RC/ACKR2/CCR3/IL1RAP/IL7R/OSMR/IL31RA/IL15RA/CD44/FZD4/C3AR1/KLRD1/KLRC4-KLRK1/FLT3/IL4R/IL21R/CCR7/EBI3/IL27RA/IL12RB1/C5AR1/FPR1/IL2RB/IL13RA1 | 28 |
| HALLMARK_ANGIOGENESIS | HALLMARK_ANGIOGENESIS | HALLMARK_ANGIOGENESIS | 13/1438 | 36/23056 | 0.3611111 | 5.789832 | 7.417765 | 0.0000001 | 0.0000022 | 0.0000014 | COL3A1/COL5A2/FSTL1/SLCO2A1/CXCL6/SPP1/TNFRSF21/PDGFA/STC1/NRP1/LUM/POSTN/THBD | 13 |
| CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | 31/1438 | 175/23056 | 0.1771429 | 2.840199 | 6.302321 | 0.0000001 | 0.0000022 | 0.0000014 | HSD11B1/SRD5A2/DPP4/CAVIN2/AOX1/BHLHE40/RTP3/ALDH1L1/AADAC/MME/SLC4A4/ABCG2/ADRB2/CAP2/UST/CD36/PDK4/MAP3K8/FAS/ACSL5/HEPACAM/ACSS3/HPD/TNFRSF19/BMP4/ACSM3/SALL1/SLC47A1/ANKFN1/CRLS1/SMPX | 31 |
| CAIRO_LIVER_DEVELOPMENT_UP | CAIRO_LIVER_DEVELOPMENT_UP | CAIRO_LIVER_DEVELOPMENT_UP | 30/1438 | 166/23056 | 0.1807229 | 2.897599 | 6.328340 | 0.0000001 | 0.0000022 | 0.0000014 | CRABP2/TGFB2/NPAS2/RPRM/COL5A2/SERPINE2/ACKR3/RARB/PDGFC/PLK2/PPIC/GJA1/SEMA3A/SEMA3D/MEST/PTN/TRPS1/CCN4/GAS1/ITGA8/WT1/SERPINH1/HMGA2/CPM/EDNRB/BNC1/COLEC12/CYSLTR1/LPAR4/PLS3 | 30 |
| GOBP_SEX_DIFFERENTIATION | GOBP_SEX_DIFFERENTIATION | GOBP_SEX_DIFFERENTIATION | 42/1438 | 281/23056 | 0.1494662 | 2.396448 | 6.074395 | 0.0000001 | 0.0000022 | 0.0000014 | TGFB2/OSR1/SRD5A2/IL1A/WNT5A/FOXL2/SLIT2/KDR/EREG/TLR3/FST/FOXC1/BMP6/GJA1/CITED2/PDGFA/INHBA/SEMA3A/SHH/ZFPM2/DMRT2/DMRTA1/AKR1C3/WT1/FZD4/PGR/YBX3/MMP14/SIX4/CYP19A1/SOX8/NUPR1/SALL1/MMP2/LHX1/SOX9/GATA6/AXL/CEBPB/TFAP2C/COL9A3/DACH2 | 42 |
| GOBP_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 40/1438 | 261/23056 | 0.1532567 | 2.457223 | 6.106336 | 0.0000001 | 0.0000022 | 0.0000014 | RNF220/LGR6/WNT5A/WWTR1/EGF/NKD2/SEMA5A/DAB2/TPBG/TBX18/RSPO3/GLI3/HECW1/FZD1/CAV1/SHH/ZNF703/FZD6/CTHRC1/RSPO2/NOTCH1/DKK1/HHEX/TCF7L2/FGFR2/FZD4/YAP1/WNT10B/IGFBP6/GLI1/LATS2/FOXO1/DACT1/JUP/COL1A1/NOG/SOX9/TGFB1/APOE/BMP2 | 40 |
| PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | 14/1438 | 42/23056 | 0.3333333 | 5.344460 | 7.268062 | 0.0000001 | 0.0000023 | 0.0000015 | NIBAN1/LMOD1/PRELP/CRIM1/SUSD5/MYLK/SOD3/ID4/GJA1/TPD52L1/CPED1/FIBIN/ACTC1/PTGIS | 14 |
| REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | 33/1438 | 194/23056 | 0.1701031 | 2.727327 | 6.231214 | 0.0000001 | 0.0000024 | 0.0000015 | GYPC/ITGA6/ITGA4/FN1/JCHAIN/SLC7A11/GYPA/CAV1/DOK2/TNFRSF10A/ANGPT1/TEK/CD44/MMP1/ITGA5/SELPLG/SLC7A7/GRB7/ITGA3/COL1A1/PECAM1/SLC16A3/SLC7A10/MAG/TGFB1/PSG5/PSG4/PSG9/SIRPG/SIRPA/THBD/PROCR/SDC4 | 33 |
| GOBP_RESPONSE_TO_INTERLEUKIN_1 | GOBP_RESPONSE_TO_INTERLEUKIN_1 | GOBP_RESPONSE_TO_INTERLEUKIN_1 | 27/1438 | 140/23056 | 0.1928571 | 3.092152 | 6.403863 | 0.0000001 | 0.0000024 | 0.0000015 | TRIM63/ZC3H12A/GBP3/GBP1/GBP2/IL1R1/IL1B/IRAK2/HES1/CXCL8/ADAMTS12/PCSK1/EDN1/IL6/CCL26/HAS2/ANXA1/ANKRD1/MYLK3/MMP2/CCL5/SOX9/TNFRSF11A/KLF2/SIRPA/PTGIS/CEBPB | 27 |
| GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING | GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING | GOBP_SECOND_MESSENGER_MEDIATED_SIGNALING | 44/1438 | 302/23056 | 0.1456954 | 2.335989 | 6.027424 | 0.0000001 | 0.0000024 | 0.0000015 | EDN2/GBP1/VCAM1/CASQ1/PTPRC/NR5A2/ATP2B4/AGT/SCTR/TRPM8/ACKR3/HRH1/ACKR2/CCR3/KDR/CXCL8/MYOZ2/EDN1/CAP2/ITPR3/RCAN2/ADGRG6/AHR/AQP1/CD36/MYOZ1/ADM/PTPRJ/IGF1/EDNRB/NFATC4/SLC24A4/THBS1/LAT/CDH13/CCR7/GIP/SOX9/CD22/APOE/FPR1/PRNP/NFATC2/GUCY2F | 44 |
| GOBP_POSITIVE_REGULATION_OF_CELL_MATRIX_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_MATRIX_ADHESION | GOBP_POSITIVE_REGULATION_OF_CELL_MATRIX_ADHESION | 16/1438 | 55/23056 | 0.2909091 | 4.664256 | 7.016944 | 0.0000001 | 0.0000025 | 0.0000016 | CSF1/S100A10/KDR/UTRN/CD36/PLEKHA2/TEK/NRP1/PTPRJ/EFEMP2/CDH13/CCR7/JUP/RRAS/RIN2/SDC4 | 16 |
| KEGG_BASAL_CELL_CARCINOMA | KEGG_BASAL_CELL_CARCINOMA | KEGG_BASAL_CELL_CARCINOMA | 16/1438 | 55/23056 | 0.2909091 | 4.664256 | 7.016944 | 0.0000001 | 0.0000025 | 0.0000016 | PTCH2/WNT9A/WNT5A/LEF1/GLI3/FZD1/SHH/FZD6/FZD8/TCF7L2/FZD4/WNT10B/GLI1/BMP4/BMP2/WNT7B | 16 |
| GOBP_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 24/1438 | 115/23056 | 0.2086957 | 3.346097 | 6.504934 | 0.0000001 | 0.0000025 | 0.0000016 | HJV/ATP2B4/AGT/CRIM1/DLX1/PPARG/WNT5A/SLIT2/ADAMTS12/BMPER/FZD1/SULF1/NOTCH1/DKK1/MMRN2/HHEX/HTRA1/CREB3L1/THBS1/FBN1/RBPMS2/SMAD6/NOG/FSTL3 | 24 |
| GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 29/1438 | 158/23056 | 0.1835443 | 2.942836 | 6.320043 | 0.0000001 | 0.0000025 | 0.0000016 | TNFRSF4/VCAM1/CSF1/PTPN22/PTPRC/IL1A/IL1B/TGFBR2/BCL6/HES1/IL15/CSF2/HLA-E/IL6/SHH/CD274/PDCD1LG2/ANXA1/NCKAP1L/IGF1/TNFSF13B/CCL5/EBI3/TNFSF9/CD70/IL27RA/IL12RB1/NFATC2/ICOSLG | 29 |
| GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | 29/1438 | 158/23056 | 0.1835443 | 2.942836 | 6.320043 | 0.0000001 | 0.0000025 | 0.0000016 | ERRFI1/PTCH2/OSR1/IL1A/IL1B/WWTR1/HES1/GDNF/FOXC1/BMP6/CD109/HOXA7/SERPINE1/CAV1/AQP3/S1PR3/NOTCH1/VCL/PLAAT4/YAP1/TNFRSF1A/WNT10B/BMP4/ZFP36L1/LHX1/SOX9/ZFP36/CEBPB/LIF | 29 |
| GOBP_PROTEIN_MATURATION | GOBP_PROTEIN_MATURATION | GOBP_PROTEIN_MATURATION | 45/1438 | 313/23056 | 0.1437700 | 2.305118 | 5.995874 | 0.0000001 | 0.0000025 | 0.0000016 | ECE1/HJV/CTSS/S100A10/IFI16/DPP4/CASP8/SERPINE2/MME/ADAMTS3/NKD2/PCSK1/ADAM19/ADAMTS2/PLA2G7/PERP/GLI3/SERPINE1/SHH/PLAT/ASPH/PCSK5/GAS1/GSN/SRGN/PLAU/NLRP6/TSPAN32/MYRF/SERPINH1/CASP4/CASP1/CARD16/C1R/C1RL/CPM/MMP14/THBS1/ANXA2/KLK6/PRNP/RUNX1/BACE2/GGT1/MYH9 | 45 |
| GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | 23/1438 | 107/23056 | 0.2149533 | 3.446427 | 6.541790 | 0.0000001 | 0.0000025 | 0.0000016 | RUNX3/PTPRC/ITPKB/NLRP3/TGFBR2/BCL6/LEF1/IL15/IL7R/VNN1/GLI3/SHH/ANXA1/IL15RA/NCKAP1L/TESPA1/MMP14/IL4R/TNFSF9/IL12RB1/AXL/IL4I1/RUNX1 | 23 |
| POOLA_INVASIVE_BREAST_CANCER_DN | POOLA_INVASIVE_BREAST_CANCER_DN | POOLA_INVASIVE_BREAST_CANCER_DN | 26/1438 | 132/23056 | 0.1969697 | 3.158090 | 6.413064 | 0.0000001 | 0.0000026 | 0.0000017 | ECE1/LAMB3/WNT5A/MYLK/FGFR3/EREG/INPP4B/PDGFA/PTN/ARHGEF5/STC1/PLAT/MATN2/TPM2/PPP1R3C/PGGHG/SAA1/ITGA7/CA12/ANPEP/NQO1/KRT17/CNN1/SDC4/CELSR1/COL4A5 | 26 |
| GOMF_AMIDE_BINDING | GOMF_AMIDE_BINDING | GOMF_AMIDE_BINDING | 54/1438 | 409/23056 | 0.1320293 | 2.116877 | 5.877813 | 0.0000002 | 0.0000027 | 0.0000017 | ECE1/HSPG2/LDLRAP1/PLA2G4A/TGFB2/SRD5A2/SCTR/EPHA4/PPARG/VIPR1/TMEM158/MME/NPR3/ITGA2/CRHBP/ACOT12/ERAP2/LVRN/PPIC/ADRB2/HFE/HLA-E/HLA-C/TAPBP/HCRTR2/INHBA/CD36/GPR37/MSR1/CLU/FZD6/PCSK5/NPY4R2/NLRP6/CCKBR/FZD4/CRYAB/APOA1/SOAT2/EDNRB/NFKBIA/BDKRB1/CRIP1/ANPEP/GLP2R/EBI3/CLEC4M/CACNA1A/MAG/APOE/PRNP/KDELR3/PNPLA3/ITM2A | 54 |
| GOBP_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | 12/1438 | 31/23056 | 0.3870968 | 6.206470 | 7.481326 | 0.0000002 | 0.0000027 | 0.0000017 | CCN1/BMP10/WNT5A/FGF18/BMP6/RUNX2/GLI3/LOXL2/GDF6/BMP4/SOX9/BMP2 | 12 |
| GOMF_FIBRONECTIN_BINDING | GOMF_FIBRONECTIN_BINDING | GOMF_FIBRONECTIN_BINDING | 12/1438 | 31/23056 | 0.3870968 | 6.206470 | 7.481326 | 0.0000002 | 0.0000027 | 0.0000017 | CTSS/ITGA4/CCDC80/LRRC15/CCN2/PLEKHA2/IGFBP6/THBS1/MMP2/ITGA3/FSTL3/SDC4 | 12 |
| JACKSON_DNMT1_TARGETS_UP | JACKSON_DNMT1_TARGETS_UP | JACKSON_DNMT1_TARGETS_UP | 20/1438 | 84/23056 | 0.2380952 | 3.817471 | 6.671969 | 0.0000002 | 0.0000028 | 0.0000018 | EPHA2/CCN1/CSF1/PTGS2/ACKR3/IL1RAP/CXCL2/EREG/HLA-E/THBS2/PDGFA/SEMA3C/KLF4/CRYAB/IGFBP6/PHLDA1/SOCS3/ZFP36/PROCR/MX1 | 20 |
| NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | 20/1438 | 84/23056 | 0.2380952 | 3.817471 | 6.671969 | 0.0000002 | 0.0000028 | 0.0000018 | TNFRSF1B/RHOC/IFI16/PTGS2/MYO10/DAB2/IER3/CITED2/MSR1/CEBPD/APBB1IP/SRGN/CD44/CASP4/C3AR1/NFKBIA/MT1X/TNFSF9/TGFB1/SAT1 | 20 |
| GOBP_REGULATION_OF_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS | GOBP_REGULATION_OF_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS | GOBP_REGULATION_OF_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS | 10/1438 | 21/23056 | 0.4761905 | 7.634943 | 7.845253 | 0.0000002 | 0.0000028 | 0.0000018 | AGT/GDNF/BMP4/SIX1/SIX4/SOX8/LHX1/HOXB7/NOG/SOX9 | 10 |
| GOBP_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM | GOBP_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM | GOBP_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM | 28/1438 | 150/23056 | 0.1866667 | 2.992898 | 6.315536 | 0.0000002 | 0.0000028 | 0.0000018 | TGFB2/OSR1/WNT5A/VEGFC/IRX2/GDNF/TFAP2A/TBX18/CITED2/FZD1/SHH/SULF1/FZD6/CTHRC1/FGFR2/ADM/BMP4/SIX1/SIX4/ALDH1A2/ALDH1A3/SOX8/NOG/SOX9/TGFB1/SDC4/WNT7B/CELSR1 | 28 |
| GOBP_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | GOBP_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | GOBP_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | 15/1438 | 49/23056 | 0.3061224 | 4.908177 | 7.063120 | 0.0000002 | 0.0000028 | 0.0000018 | TGFB2/BMP10/PPARG/TGFBR2/BMP3/DAB2/BMP6/HFE/INHBA/RBPMS/GDF6/BMP4/GDF15/TGFB1/BMP2 | 15 |
| GOBP_REGULATION_OF_BINDING | GOBP_REGULATION_OF_BINDING | GOBP_REGULATION_OF_BINDING | 50/1438 | 367/23056 | 0.1362398 | 2.184384 | 5.898916 | 0.0000002 | 0.0000029 | 0.0000018 | LDLRAP1/RNF220/S100A10/IFI16/ITGA4/EPHA4/SP100/PPARG/XIRP1/WNT5A/HES1/LEF1/EGF/DAB2/ITGA2/STING1/ADRB2/FOXC1/HFE/MDFI/CAV1/MET/EBF2/CTHRC1/ANGPT1/KLF4/NRP1/DKK1/TCF7L2/PHLDA2/CARD16/UBASH3B/HMGA2/IGF1/NFATC4/NFKBIA/BMP4/DACT1/ANXA2/MYOCD/CSF3/NOG/TMC8/TGFB1/BCL3/APOE/BMP2/LIF/HMOX1/PDGFB | 50 |
| LENAOUR_DENDRITIC_CELL_MATURATION_UP | LENAOUR_DENDRITIC_CELL_MATURATION_UP | LENAOUR_DENDRITIC_CELL_MATURATION_UP | 24/1438 | 116/23056 | 0.2068966 | 3.317251 | 6.452970 | 0.0000002 | 0.0000029 | 0.0000019 | CSF1/ECM1/CRABP2/FCGR2A/HSD11B1/ITPKB/TGFA/SULT1C2/DPP4/PPARG/ITGB5/MGLL/SPP1/PPIC/CITED2/INHBA/SEMA3C/IDO1/FABP4/BIRC3/CCR7/GDF15/APOE/TGM2 | 24 |
| SENESE_HDAC2_TARGETS_UP | SENESE_HDAC2_TARGETS_UP | SENESE_HDAC2_TARGETS_UP | 24/1438 | 116/23056 | 0.2068966 | 3.317251 | 6.452970 | 0.0000002 | 0.0000029 | 0.0000019 | ZC3H12A/TGFB2/IL1A/KYNU/ITGA6/TGFBR2/AADAC/CXCL8/IL7R/OSMR/ADAMTS6/CSF2/GFPT2/TNFAIP3/INHBA/ASPH/TNFRSF11B/FBXO32/PLAU/SAA1/HMGA2/RBPMS2/BCL2A1/TGM2 | 24 |
| GOBP_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS | 46/1438 | 325/23056 | 0.1415385 | 2.269340 | 5.943805 | 0.0000002 | 0.0000029 | 0.0000019 | ERRFI1/RPE65/IFI16/PTGS2/AGT/IL1B/ITGB6/CASP8/MYLK/MME/TLR3/ITGA2/BMP6/GJA1/PTPRK/AQP1/TNFRSF10A/FAS/ANKRD1/BAG3/YAP1/MMP1/MMP3/CASP1/CARD16/CRYAB/TNFRSF1A/SCNN1A/YBX3/HMGA2/NFATC4/ZFP36L1/SLC24A4/CRIP1/BMF/MMP2/PIEZO1/COL1A1/KCNJ2/SOX9/PIEZO2/CNN2/TNFSF14/MAG/RELB/GUCY2F | 46 |
| HP_ABNORMALITY_OF_THE_SYNOVIA | HP_ABNORMALITY_OF_THE_SYNOVIA | HP_ABNORMALITY_OF_THE_SYNOVIA | 46/1438 | 325/23056 | 0.1415385 | 2.269340 | 5.943805 | 0.0000002 | 0.0000029 | 0.0000019 | AGRN/HSPG2/PTPN22/TBX15/PRG4/TGFB2/COL3A1/COL5A2/COL6A3/TGFBR2/WNT5A/CD96/FGFRL1/FGFR3/ADAMTS2/HFE/COL12A1/TENT5A/GJA1/GLI3/SHH/CSGALNACT1/EXT1/COLEC10/TPM2/GAS1/COL5A1/COL13A1/FGFR2/EFEMP2/ITGA7/ZIC2/SIX1/FBLN5/FBN1/SMAD6/MMP2/MYH8/COL1A1/SOX9/PIEZO2/COL9A3/COL6A2/IL2RB/GPC4/BGN | 46 |
| GOMF_METALLOPEPTIDASE_ACTIVITY | GOMF_METALLOPEPTIDASE_ACTIVITY | GOMF_METALLOPEPTIDASE_ACTIVITY | 33/1438 | 196/23056 | 0.1683673 | 2.699498 | 6.162611 | 0.0000002 | 0.0000030 | 0.0000019 | MMP23B/ECE1/TRABD2B/TRABD2A/MME/ADAMTS3/ADAMTS16/ADAMTS12/ADAMTS6/ERAP2/LVRN/ADAM19/ADAMTS2/CPA2/CPA4/CPA5/ADAM28/ADAM9/ADAM32/PAPPA/TLL2/MMP10/MMP1/MMP3/ADAMTS8/ADAMTS15/CPM/MMP14/ANPEP/MMP2/ADAMTS18/ADAM33/ADAMTS5 | 33 |
| FRIDMAN_SENESCENCE_UP | FRIDMAN_SENESCENCE_UP | FRIDMAN_SENESCENCE_UP | 19/1438 | 77/23056 | 0.2467532 | 3.956288 | 6.701636 | 0.0000002 | 0.0000030 | 0.0000020 | S100A11/IFI16/FN1/SPARC/TFAP2A/CCN2/TNFAIP3/CITED2/SERPINE1/GSN/CD44/MMP1/CRYAB/IGFBP6/TNFAIP2/THBS1/ALDH1A3/SERPINB2/RRAS | 19 |
| BERENJENO_TRANSFORMED_BY_RHOA_DN | BERENJENO_TRANSFORMED_BY_RHOA_DN | BERENJENO_TRANSFORMED_BY_RHOA_DN | 53/1438 | 400/23056 | 0.1325000 | 2.124423 | 5.850895 | 0.0000002 | 0.0000030 | 0.0000020 | TBX15/S100A13/FN1/SERPINE2/COL6A3/BHLHE40/LAMB2/CCDC80/IGSF10/MYO10/NPR3/OSMR/ID4/HLA-E/TAPBP/PLA2G7/CRYBG1/LAMA4/LAMA2/THBS2/FZD1/PDK4/CAV1/PLAT/MATN2/TNFRSF11B/GAS1/GSN/COL5A1/NACC2/FGFR2/IFITM3/NNMT/C1R/LUM/POSTN/MMP14/SIX1/SIX4/SMAD6/MT1X/FOXF1/COPZ2/COL1A1/MRC2/CACNA1A/RRAS/PRNP/RIN2/COL6A2/KDELR3/COL4A5/GPC4 | 53 |
| VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 | VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 | VERRECCHIA_DELAYED_RESPONSE_TO_TGFB1 | 13/1438 | 37/23056 | 0.3513514 | 5.633350 | 7.274564 | 0.0000002 | 0.0000030 | 0.0000020 | EPHA2/ITGA4/COL8A1/DSP/DDR1/THBS2/ITGB8/EPHB4/MMP1/TNFRSF1A/ITGA5/THBS1/MMP2 | 13 |
| ABBUD_LIF_SIGNALING_1_UP | ABBUD_LIF_SIGNALING_1_UP | ABBUD_LIF_SIGNALING_1_UP | 14/1438 | 43/23056 | 0.3255814 | 5.220170 | 7.143842 | 0.0000002 | 0.0000030 | 0.0000020 | ELF3/IL1R1/NMI/GRAMD2B/PSMB8/TAPBP/ST3GAL1/ANXA8L1/VWF/TNFRSF1A/SOCS3/BCL3/HAS1/CEBPB | 14 |
| GOBP_SARCOMERE_ORGANIZATION | GOBP_SARCOMERE_ORGANIZATION | GOBP_SARCOMERE_ORGANIZATION | 14/1438 | 43/23056 | 0.3255814 | 5.220170 | 7.143842 | 0.0000002 | 0.0000030 | 0.0000020 | CASQ1/BMP10/MYOZ2/EDN1/LMOD2/FLNC/MYPN/MYOZ1/SYNPO2L/ANKRD1/SIX4/TPM1/MYLK3/KRT19 | 14 |
| GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | 14/1438 | 43/23056 | 0.3255814 | 5.220170 | 7.143842 | 0.0000002 | 0.0000030 | 0.0000020 | PTGS2/CD34/TGFB2/LTBP1/ITGB6/COL3A1/FN1/ITGB8/LRRC32/LUM/THBS1/GATA6/SERPINB7/PSG9 | 14 |
| HARRIS_BRAIN_CANCER_PROGENITORS | HARRIS_BRAIN_CANCER_PROGENITORS | HARRIS_BRAIN_CANCER_PROGENITORS | 14/1438 | 43/23056 | 0.3255814 | 5.220170 | 7.143842 | 0.0000002 | 0.0000030 | 0.0000020 | DHRS3/CAPG/AOX1/WNT5A/TMEM212/GJA1/CAV1/PAPSS2/CASP4/OPCML/COL6A2/LGALS2/SRPX2/BGN | 14 |
| GOBP_REGULATION_OF_TUBE_SIZE | GOBP_REGULATION_OF_TUBE_SIZE | GOBP_REGULATION_OF_TUBE_SIZE | 27/1438 | 142/23056 | 0.1901408 | 3.048600 | 6.315463 | 0.0000002 | 0.0000031 | 0.0000020 | ECE1/HTR1D/EDN2/PTGS2/AGT/CPS1/HRH1/SOD3/NPR3/F2RL1/ADRB2/FOXC1/EDN1/SOD2/CAV1/EXT1/HTR7/ADM/P2RY2/ARHGAP42/KCNA5/EDNRB/MMP2/KLF2/APOE/ADRA1D/CYSLTR1 | 27 |
| PROVENZANI_METASTASIS_DN | PROVENZANI_METASTASIS_DN | PROVENZANI_METASTASIS_DN | 27/1438 | 142/23056 | 0.1901408 | 3.048600 | 6.315463 | 0.0000002 | 0.0000031 | 0.0000020 | S100A11/S100A2/LAMC2/NMI/PDGFC/PPIC/PSMB9/TRIP6/SERPINE1/CLU/IFITM2/IFITM3/SAA1/CD44/TNFAIP2/EHD4/TPM1/COTL1/CLDN7/KRT13/WIPI1/BLVRB/RRAS/KLK6/TGM2/SDC4/SPANXA1 | 27 |
| GOBP_MESENCHYME_MORPHOGENESIS | GOBP_MESENCHYME_MORPHOGENESIS | GOBP_MESENCHYME_MORPHOGENESIS | 16/1438 | 56/23056 | 0.2857143 | 4.580966 | 6.919656 | 0.0000002 | 0.0000032 | 0.0000020 | TGFB2/OSR1/ACTG2/TGFBR2/WNT5A/LEF1/FOXC1/NOTCH1/BMP4/ACTC1/FOXF1/NOG/SOX9/TGFB1/BMP2/GATA5 | 16 |
| RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | RASHI_RESPONSE_TO_IONIZING_RADIATION_2 | 25/1438 | 125/23056 | 0.2000000 | 3.206676 | 6.380230 | 0.0000002 | 0.0000032 | 0.0000020 | CSF1/S100A13/LAMC2/TGFB2/MGLL/WWTR1/CXCL3/CXCL2/PLK2/EDN1/TNFAIP3/CEBPD/ANXA1/KLF4/MAP3K8/NFKB2/PRSS23/BIRC3/SLC7A7/NFKBIA/THBS1/CLDN7/KRT19/ICAM1/RELB | 25 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN | 28/1438 | 151/23056 | 0.1854305 | 2.973077 | 6.273669 | 0.0000002 | 0.0000032 | 0.0000020 | FUCA1/IL1R1/NRP2/STAB1/CXCL1/CXCL5/CXCL3/CXCL2/ANXA3/IL7R/C9/DAB2/TGFBI/ADTRP/PLA2G7/GPNMB/PDK4/PCSK5/NRP1/PYROXD2/SLCO2B1/MMP1/EMP1/MAF/SLFN13/KLF2/APOE/C5AR1 | 28 |
| GOBP_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 42/1438 | 285/23056 | 0.1473684 | 2.362814 | 5.970658 | 0.0000002 | 0.0000032 | 0.0000020 | RUNX3/ZC3H12A/CSF1/PTPRC/ITPKB/NLRP3/CYP26B1/CASP8/TGFBR2/MITF/BCL6/LEF1/IL15/TLR3/IL7R/VNN1/HOXA7/INHBA/GLI3/SHH/ANXA1/IL15RA/UBASH3B/NCKAP1L/TESPA1/MMP14/BMP4/ZFP36L1/FOS/FBN1/IL4R/FSTL3/TNFSF9/IL12RB1/AXL/TGFB1/PSG9/IL4I1/CEBPB/RUNX1/LIF/LGALS1 | 42 |
| BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | 52/1438 | 390/23056 | 0.1333333 | 2.137784 | 5.844656 | 0.0000002 | 0.0000032 | 0.0000020 | TNFRSF9/SYNC/GBP1/CSF1/CTSS/MR1/EFEMP1/ITGA6/SEMA3B/WWTR1/FGFR3/LEF1/MYO10/GMPR/ID4/TRIM38/GPSM3/RUNX2/CYP39A1/TENT5A/CRYBG1/LAMA4/GJA1/LAMA2/TNS3/MET/FLNC/CLU/PLAG1/MATN2/ANGPT1/TNFRSF11B/PTGS1/CD44/EFEMP2/H2AJ/EPS8/ITGA7/CPM/OASL/NPAS3/FBN1/COTL1/DLX4/SLC14A1/MBP/KLF2/PTGIS/PDGFB/LPAR4/IL13RA1/BGN | 52 |
| GOBP_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT | GOBP_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT | GOBP_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT | 18/1438 | 70/23056 | 0.2571429 | 4.122869 | 6.748781 | 0.0000002 | 0.0000032 | 0.0000020 | TBX15/PRRX1/TGFB2/DLX2/TGFBR2/TFAP2A/RUNX2/HOXA1/HOXA2/GLI3/EXT1/COLEC10/FGFR2/MMP14/BMP4/SIX1/SIX4/LHX1 | 18 |
| PID_AP1_PATHWAY | PID_AP1_PATHWAY | PID_AP1_PATHWAY | 18/1438 | 70/23056 | 0.2571429 | 4.122869 | 6.748781 | 0.0000002 | 0.0000032 | 0.0000020 | CCN1/AGT/CXCL8/CSF2/EDN1/GJA1/IL6/TRIP6/FABP4/PLAU/TCF7L2/FOSL1/MMP1/FOS/MT2A/MAF/TGFB1/NFATC2 | 18 |
| YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | 18/1438 | 70/23056 | 0.2571429 | 4.122869 | 6.748781 | 0.0000002 | 0.0000032 | 0.0000020 | SPSB1/CFH/LTBP1/BHLHE40/MITF/BCL6/TGFBI/CITED2/FAM20C/PDK4/MSC/MAP3K8/KRT7/TNS2/BMP4/GADD45B/CEBPB/SAT1 | 18 |
| HP_PLANTAR_HYPERKERATOSIS | HP_PLANTAR_HYPERKERATOSIS | HP_PLANTAR_HYPERKERATOSIS | 29/1438 | 160/23056 | 0.1812500 | 2.906050 | 6.239772 | 0.0000002 | 0.0000032 | 0.0000020 | TNFRSF1B/NEXN/LAMC2/LAMB3/DES/COL7A1/TNNC1/SLCO2A1/DSP/CAP2/LAMA4/GJA1/PERP/SASH1/COL14A1/MYPN/VCL/ANKRD1/BAG3/FGFR2/CRYAB/ACTC1/TPM1/KRT17/JUP/ITGB4/RHBDF2/DSG2/SERPINB7 | 29 |
| RODRIGUES_NTN1_TARGETS_DN | RODRIGUES_NTN1_TARGETS_DN | RODRIGUES_NTN1_TARGETS_DN | 29/1438 | 160/23056 | 0.1812500 | 2.906050 | 6.239772 | 0.0000002 | 0.0000032 | 0.0000020 | TNFRSF1B/HSPG2/FN1/TGFBR2/TNNC1/MYLK/ITGB5/EREG/IER3/TNFRSF21/MET/C9orf152/TNFSF15/PAPSS2/MYOF/AHNAK/PLAAT3/KRT18/IRF9/MSLN/KRT13/SOX9/ITGB4/KLF2/BCAM/NECTIN2/KLK6/ADAMTS5/CYSLTR1 | 29 |
| DURCHDEWALD_SKIN_CARCINOGENESIS_DN | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | 40/1438 | 265/23056 | 0.1509434 | 2.420133 | 5.996867 | 0.0000002 | 0.0000032 | 0.0000021 | FBLIM1/CRABP2/PTGS2/IL36G/ITGA6/VGLL3/PHLDB2/PLD1/ARAP2/GPAT3/PLK2/ELL2/TGFBI/TPBG/STX11/UTRN/MAFK/HOXA1/SEMA3C/MET/PTPRZ1/FABP4/LY6K/B4GALT1/AQP3/CD44/MMP10/MMP3/MPZL2/UBASH3B/EPS8/PHLDA1/FOS/TPM1/ALDH1A3/KRT13/KCNN4/RUNX1/HMOX1/MYH9 | 40 |
| WILCOX_RESPONSE_TO_PROGESTERONE_DN | WILCOX_RESPONSE_TO_PROGESTERONE_DN | WILCOX_RESPONSE_TO_PROGESTERONE_DN | 17/1438 | 63/23056 | 0.2698413 | 4.326467 | 6.818832 | 0.0000002 | 0.0000032 | 0.0000021 | ATP2B4/COL5A2/FN1/DES/MME/SPON2/INHBA/LOXL2/PLAU/MICAL2/THBS1/MMP2/PIEZO1/MYH1/COL1A1/PECAM1/MYL9 | 17 |
| NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN | 20/1438 | 85/23056 | 0.2352941 | 3.772560 | 6.604724 | 0.0000002 | 0.0000033 | 0.0000021 | IFI44L/LMOD1/AGT/PPARG/VIPR1/P3H2/CD36/PDK4/MEST/FABP4/ANGPT1/AQP7/AKR1C3/PLAAT3/FZD4/IGF1/CES1/CETP/ABCA8/SLC7A10 | 20 |
| GOBP_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA | GOBP_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA | GOBP_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA | 24/1438 | 117/23056 | 0.2051282 | 3.288898 | 6.401569 | 0.0000002 | 0.0000033 | 0.0000021 | GBP3/GBP1/GBP2/GBP4/GBP5/RAB7B/NMI/SP100/PPARG/WNT5A/PARP14/CLDN1/TXK/TLR3/EDN1/CCL26/ZYX/GSN/CASP1/RAB20/NLRC5/CCL5/IL12RB1/SIRPA | 24 |
| KANG_IMMORTALIZED_BY_TERT_DN | KANG_IMMORTALIZED_BY_TERT_DN | KANG_IMMORTALIZED_BY_TERT_DN | 22/1438 | 101/23056 | 0.2178218 | 3.492419 | 6.474368 | 0.0000002 | 0.0000035 | 0.0000023 | DHRS3/PRELP/MGLL/ADAMTS3/ADAM19/TNFAIP3/THBS2/ZFPM2/ST3GAL1/PTGS1/NRP1/CD44/MMP1/MMP3/CASP1/SERPINA10/ALDH1A3/MYH4/MYH1/MYH2/ST8SIA5/ARHGEF6 | 22 |
| KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | 39/1438 | 256/23056 | 0.1523438 | 2.442585 | 5.986159 | 0.0000002 | 0.0000035 | 0.0000023 | HSPG2/S100A13/MR1/CFH/PRELP/EFEMP1/VAMP5/IL1R1/EPHA4/MYLK/HEG1/SOD3/FAM114A1/ID4/DDR1/CCN2/MYL7/TRIP6/RARRES2/GAS1/FGFR2/SLC22A18/ADM/MICAL2/PRSS23/TAGLN/KCNA5/C1R/EPS8/IGFBP6/CRIP1/ALDH1A2/NUPR1/MYL4/SERPINB8/TGFB1/PTGIS/SAT1/COL4A6 | 39 |
| GOBP_REGULATION_OF_ODONTOGENESIS | GOBP_REGULATION_OF_ODONTOGENESIS | GOBP_REGULATION_OF_ODONTOGENESIS | 9/1438 | 17/23056 | 0.5294118 | 8.488260 | 7.965771 | 0.0000002 | 0.0000036 | 0.0000023 | CSF1/CD34/EDN1/RUNX2/SHH/RSPO2/TNFRSF11B/BMP4/BMP2 | 9 |
| GOMF_DEATH_RECEPTOR_ACTIVITY | GOMF_DEATH_RECEPTOR_ACTIVITY | GOMF_DEATH_RECEPTOR_ACTIVITY | 8/1438 | 13/23056 | 0.6153846 | 9.866695 | 8.247422 | 0.0000002 | 0.0000036 | 0.0000023 | TNFRSF18/TNFRSF4/TNFRSF1B/TNFRSF10A/FAS/TNFRSF1A/TNFRSF19/TNFRSF11A | 8 |
| RAY_ALZHEIMERS_DISEASE | RAY_ALZHEIMERS_DISEASE | RAY_ALZHEIMERS_DISEASE | 8/1438 | 13/23056 | 0.6153846 | 9.866695 | 8.247422 | 0.0000002 | 0.0000036 | 0.0000023 | CSF1/IL1A/CXCL8/EGF/GDNF/CCL5/CSF3/IL11 | 8 |
| REACTOME_DISSOLUTION_OF_FIBRIN_CLOT | REACTOME_DISSOLUTION_OF_FIBRIN_CLOT | REACTOME_DISSOLUTION_OF_FIBRIN_CLOT | 8/1438 | 13/23056 | 0.6153846 | 9.866695 | 8.247422 | 0.0000002 | 0.0000036 | 0.0000023 | S100A10/SERPINE2/SERPINE1/PLAT/PLAU/ANXA2/SERPINB2/SERPINB8 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_ACTIVATION | 29/1438 | 161/23056 | 0.1801242 | 2.888000 | 6.200102 | 0.0000002 | 0.0000036 | 0.0000023 | RUNX3/ZC3H12A/PTPN22/ILDR2/LAX1/BCL6/HFE/MICA/TNFRSF21/TNFAIP3/GPNMB/INHBA/GLI3/SHH/IDO1/CD274/PDCD1LG2/ANXA1/SFTPD/LRRC32/NCKAP1L/BMP4/IL4R/AXL/IL4I1/PRNP/SDC4/CEBPB/RUNX1 | 29 |
| ROY_WOUND_BLOOD_VESSEL_UP | ROY_WOUND_BLOOD_VESSEL_UP | ROY_WOUND_BLOOD_VESSEL_UP | 15/1438 | 50/23056 | 0.3000000 | 4.810014 | 6.955771 | 0.0000002 | 0.0000036 | 0.0000023 | CCN1/GBP1/COL3A1/COL5A2/HEG1/SLCO2A1/SEL1L3/STC1/SULF1/NRP1/PLAU/MMP1/LUM/POSTN/NID2 | 15 |
| ZHU_CMV_8_HR_DN | ZHU_CMV_8_HR_DN | ZHU_CMV_8_HR_DN | 15/1438 | 50/23056 | 0.3000000 | 4.810014 | 6.955771 | 0.0000002 | 0.0000036 | 0.0000023 | HNMT/TFAP2A/AHR/CEBPD/GAS1/TCF7L2/ADM/MMP1/TNFRSF1A/BMP4/ZFP36L1/APOE/RUNX1/MN1/MYH9 | 15 |
| GOMF_PHOSPHOLIPID_BINDING | GOMF_PHOSPHOLIPID_BINDING | GOMF_PHOSPHOLIPID_BINDING | 59/1438 | 469/23056 | 0.1257996 | 2.016992 | 5.738906 | 0.0000002 | 0.0000037 | 0.0000024 | LDLRAP1/RPE65/PLA2G4A/NR5A2/CAPG/CAVIN2/CPS1/OSBPL10/WNT5A/ESYT3/MME/VEPH1/PLD1/ZFYVE28/ARAP2/TEC/JCHAIN/ANXA3/MYO10/IQGAP2/PXDC1/ITPR3/PLA2G7/SCIN/ANXA13/GSDMD/ANXA1/GSN/ANXA8L1/ANXA8/MYOF/PHLDA2/SYT12/SYTL2/APOC3/APOA1/PHLDA1/TPCN1/PLEK2/THBS1/PLA2G4D/TNFAIP8L3/MYO1E/ANXA2/GRAMD2A/MFGE8/CETP/ADAP2/GRB7/WIPI1/KCNJ2/AXL/APOE/PLA2G4C/SDCBP2/JPH2/PNPLA3/FRMPD4/LPAR4 | 59 |
| GOBP_VIRAL_LIFE_CYCLE | GOBP_VIRAL_LIFE_CYCLE | GOBP_VIRAL_LIFE_CYCLE | 45/1438 | 318/23056 | 0.1415094 | 2.268874 | 5.876386 | 0.0000002 | 0.0000038 | 0.0000024 | TNFRSF4/EPHA2/ZC3H12A/IFI16/RNASEL/NR5A2/ITGB6/ITGB5/CLDN1/LRRC15/CXCL8/GYPA/TRIML2/TRIML1/ITGA2/TRIM38/MOG/CAV2/CAV1/PARP10/PCSK5/GSN/NOTCH1/NRP1/IFITM2/IFITM3/TRIM5/ITGA5/HMGA2/SELPLG/TPCN1/OASL/ANPEP/CLDN6/CCL5/CLEC4M/ICAM1/AXL/NECTIN2/APOE/MX1/LGALS1/APOBEC3A/APOBEC3G/APOBEC3H | 45 |
| TSAI_RESPONSE_TO_RADIATION_THERAPY | TSAI_RESPONSE_TO_RADIATION_THERAPY | TSAI_RESPONSE_TO_RADIATION_THERAPY | 12/1438 | 32/23056 | 0.3750000 | 6.012517 | 7.318039 | 0.0000002 | 0.0000038 | 0.0000025 | CCN1/TGFB2/COL6A3/TGFBR2/VEGFC/CCN2/IL6/SERPINE1/PLAT/TNFRSF11B/THBS1/COL6A2 | 12 |
| HP_LIPOATROPHY | HP_LIPOATROPHY | HP_LIPOATROPHY | 18/1438 | 71/23056 | 0.2535211 | 4.064800 | 6.670577 | 0.0000002 | 0.0000039 | 0.0000025 | FUCA1/NEXN/COL3A1/DES/PPARG/TNNC1/DSP/CAP2/LAMA4/MYPN/VCL/ANKRD1/BAG3/CRYAB/ACTC1/FBN1/TPM1/DSG2 | 18 |
| NAGASHIMA_EGF_SIGNALING_UP | NAGASHIMA_EGF_SIGNALING_UP | NAGASHIMA_EGF_SIGNALING_UP | 16/1438 | 57/23056 | 0.2807018 | 4.500598 | 6.824635 | 0.0000002 | 0.0000040 | 0.0000026 | EPHA2/CCN1/DLX2/BHLHE40/HES1/F2RL1/HBEGF/EDN1/IER3/CCN2/TNFRSF11B/FOSL1/FOS/TNFRSF12A/ZFP36/LIF | 16 |
| GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION | 27/1438 | 144/23056 | 0.1875000 | 3.006259 | 6.228607 | 0.0000002 | 0.0000040 | 0.0000026 | RUNX3/ZC3H12A/PTPN22/ILDR2/LAX1/BCL6/ADTRP/HFE/TNFRSF21/GPNMB/GLI3/SHH/IDO1/CD274/PDCD1LG2/ANXA1/KLF4/SFTPD/LRRC32/NCKAP1L/BMP4/IL4R/IL4I1/PRNP/SDC4/CEBPB/RUNX1 | 27 |
| GOBP_CELLULAR_RESPONSE_TO_INTERLEUKIN_1 | GOBP_CELLULAR_RESPONSE_TO_INTERLEUKIN_1 | GOBP_CELLULAR_RESPONSE_TO_INTERLEUKIN_1 | 23/1438 | 110/23056 | 0.2090909 | 3.352434 | 6.378441 | 0.0000002 | 0.0000040 | 0.0000026 | ZC3H12A/GBP3/GBP1/GBP2/IL1R1/IL1B/IRAK2/HES1/CXCL8/ADAMTS12/EDN1/IL6/CCL26/HAS2/ANKRD1/MYLK3/MMP2/CCL5/SOX9/KLF2/SIRPA/PTGIS/CEBPB | 23 |
| GOBP_LUNG_ALVEOLUS_DEVELOPMENT | GOBP_LUNG_ALVEOLUS_DEVELOPMENT | GOBP_LUNG_ALVEOLUS_DEVELOPMENT | 14/1438 | 44/23056 | 0.3181818 | 5.101530 | 7.023430 | 0.0000002 | 0.0000040 | 0.0000026 | ERRFI1/EDN2/ITGB6/KDR/SLC7A11/PDGFA/SFTPD/FGFR2/PGR/BMP4/FOXF1/MYOCD/GATA6/LIF | 14 |
| NAKAMURA_METASTASIS_MODEL_DN | NAKAMURA_METASTASIS_MODEL_DN | NAKAMURA_METASTASIS_MODEL_DN | 14/1438 | 44/23056 | 0.3181818 | 5.101530 | 7.023430 | 0.0000002 | 0.0000040 | 0.0000026 | TFPI/P3H2/SNCAIP/SERPINB1/RUNX2/GLI3/PTPRZ1/PLAT/AQP3/CD44/EHBP1L1/PLEK2/C3/RAC2 | 14 |
| GOBP_EXTRACELLULAR_MATRIX_DISASSEMBLY | GOBP_EXTRACELLULAR_MATRIX_DISASSEMBLY | GOBP_EXTRACELLULAR_MATRIX_DISASSEMBLY | 17/1438 | 64/23056 | 0.2656250 | 4.258866 | 6.733214 | 0.0000002 | 0.0000040 | 0.0000026 | CTSS/CAPG/DPP4/FAP/DDR1/IL6/GSN/MMP10/MMP1/MMP3/ADAMTS15/LCP1/MMP14/MMP2/ELANE/TGFB1/ADAMTS5 | 17 |
| GOMF_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_ADHESION_MEDIATOR_ACTIVITY | 17/1438 | 64/23056 | 0.2656250 | 4.258866 | 6.733214 | 0.0000002 | 0.0000040 | 0.0000026 | NEXN/ITGA10/S100A11/ITGA2/DSP/ANXA1/MYPN/ROBO4/KRT18/GLDN/ANXA2/ITGA11/JUP/DSG2/BCAM/SIRPA/CDC42EP1 | 17 |
| KAYO_CALORIE_RESTRICTION_MUSCLE_UP | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | KAYO_CALORIE_RESTRICTION_MUSCLE_UP | 21/1438 | 94/23056 | 0.2234043 | 3.581925 | 6.469295 | 0.0000003 | 0.0000041 | 0.0000026 | HSPG2/MTMR11/S100A11/FAP/COL3A1/FN1/DES/COL6A3/TGFBR2/BCL6/LAMA2/ITGB8/PDK4/GAS1/PLAU/FAS/LUM/COL1A1/ELANE/EMP3/MYH9 | 21 |
| GOBP_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 22/1438 | 102/23056 | 0.2156863 | 3.458180 | 6.417100 | 0.0000003 | 0.0000041 | 0.0000026 | TGFB2/IL1B/EPHA4/TGFBR2/EPHA3/PHLDB2/WWTR1/LEF1/DAB2/FOXC1/IL6/LOXL2/ZNF703/CRB2/NOTCH1/TCF7L2/BCL9L/BMP4/COL1A1/NOG/TGFB1/BMP2 | 22 |
| GOBP_GRANULOCYTE_CHEMOTAXIS | GOBP_GRANULOCYTE_CHEMOTAXIS | GOBP_GRANULOCYTE_CHEMOTAXIS | 25/1438 | 127/23056 | 0.1968504 | 3.156177 | 6.284171 | 0.0000003 | 0.0000042 | 0.0000027 | EDN2/CSF1/TGFB2/IL1B/DPP4/HRH1/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EDN1/CCL26/RARRES2/ANXA1/SAA1/C3AR1/NCKAP1L/THBS1/CCL5/CCR7/C5AR1/RAC2 | 25 |
| GOBP_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE | 40/1438 | 268/23056 | 0.1492537 | 2.393042 | 5.916061 | 0.0000003 | 0.0000042 | 0.0000027 | C1QTNF12/TNFRSF1B/IFI16/PTPRC/NLRP3/NMI/PPARG/CD96/PARP14/PLK2/TRIM38/HLA-E/MICA/MICB/NT5E/TNFAIP3/TEK/KLF4/ALOX5/HTRA1/NLRP6/SAA1/APOA1/TNFRSF1A/KLRD1/IGF1/LRFN5/CYP19A1/NLRC5/FOXF1/DHX58/RHBDF2/SOCS3/METRNL/ELANE/ZFP36/APOE/SIRPA/PTGIS/USP18 | 40 |
| SABATES_COLORECTAL_ADENOMA_DN | SABATES_COLORECTAL_ADENOMA_DN | SABATES_COLORECTAL_ADENOMA_DN | 43/1438 | 299/23056 | 0.1438127 | 2.305804 | 5.861520 | 0.0000003 | 0.0000044 | 0.0000028 | CDA/MCOLN2/BRINP3/CFH/NR5A2/LMOD1/OSR1/EFEMP1/ITGA4/FN1/THRB/EPHA3/CCDC80/MYLK/SLC4A4/BMP3/ABCG2/HAPLN1/EDIL3/RBM24/RSPO3/TMEM200A/GPNMB/CD36/PTN/CLU/FABP4/CA1/RSPO2/COL14A1/TRPM6/PLAC9/CPM/TMCC3/IGF1/GLDN/ANPEP/CCL5/ABCA8/COLEC12/CNN1/CD37/LGALS2 | 43 |
| GOBP_ARTERY_MORPHOGENESIS | GOBP_ARTERY_MORPHOGENESIS | GOBP_ARTERY_MORPHOGENESIS | 19/1438 | 79/23056 | 0.2405063 | 3.856129 | 6.558417 | 0.0000003 | 0.0000044 | 0.0000028 | PRRX1/TGFB2/COL3A1/MYLK/HES1/FOXC1/EDN1/ADGRF5/CITED2/HOXA1/NOTCH1/NRP1/EFEMP2/BMP4/SIX1/FOXF1/MYOCD/NOG/APOE | 19 |
| GOBP_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR | GOBP_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR | GOBP_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR | 24/1438 | 119/23056 | 0.2016807 | 3.233623 | 6.300416 | 0.0000003 | 0.0000045 | 0.0000029 | GALNT3/CPS1/WNT5A/FGFRL1/FGFR3/CXCL8/FGF5/FGF18/RUNX2/CCN2/FAM20C/FGF20/SULF1/EXT1/FGFR2/CD44/CREB3L1/ZFP36L1/THBS1/CCL5/LHX1/COL1A1/NOG/ZFP36 | 24 |
| HALLMARK_ESTROGEN_RESPONSE_LATE | HALLMARK_ESTROGEN_RESPONSE_LATE | HALLMARK_ESTROGEN_RESPONSE_LATE | 33/1438 | 200/23056 | 0.1650000 | 2.645508 | 6.027942 | 0.0000003 | 0.0000045 | 0.0000029 | LAMC2/ATP2B4/CYP26B1/SEMA3B/TNNC1/FGFR3/FOXC1/MICB/TPBG/TPD52L1/PERP/CAV1/MEST/KLF4/CLIC3/PAPSS2/MYOF/CD44/PLAAT3/ALDH3B1/PRSS23/PGR/SCNN1A/FOS/SERPINA1/CA12/KRT13/KRT19/LLGL2/CYP4F11/ZFP36/BLVRB/TFAP2C | 33 |
| HALLMARK_XENOBIOTIC_METABOLISM | HALLMARK_XENOBIOTIC_METABOLISM | HALLMARK_XENOBIOTIC_METABOLISM | 33/1438 | 200/23056 | 0.1650000 | 2.645508 | 6.027942 | 0.0000003 | 0.0000045 | 0.0000029 | EPHA2/CDA/FMO3/HSD11B1/TGFB2/IL1R1/KYNU/AOX1/TDO2/VNN1/SLC22A1/CD36/PDK4/SERPINE1/PTGR1/AKR1C3/MBL2/PAPSS2/FAS/CYP26A1/TNFRSF1A/IGF1/SLC46A3/SERPINA6/CES1/MT2A/PSMB10/NQO1/JUP/ABCC3/BLVRB/APOE/HMOX1 | 33 |
| GOCC_COMPLEX_OF_COLLAGEN_TRIMERS | GOCC_COMPLEX_OF_COLLAGEN_TRIMERS | GOCC_COMPLEX_OF_COLLAGEN_TRIMERS | 10/1438 | 22/23056 | 0.4545455 | 7.287900 | 7.610033 | 0.0000003 | 0.0000045 | 0.0000029 | COL3A1/COL5A2/COL7A1/COL8A1/COL27A1/COL5A1/LUM/COL1A1/COL4A6/COL4A5 | 10 |
| JOHNSTONE_PARVB_TARGETS_2_UP | JOHNSTONE_PARVB_TARGETS_2_UP | JOHNSTONE_PARVB_TARGETS_2_UP | 27/1438 | 145/23056 | 0.1862069 | 2.985526 | 6.185742 | 0.0000003 | 0.0000045 | 0.0000029 | ECM1/S100A11/HEG1/SEL1L3/EREG/DDX60/FST/TNFAIP3/CITED2/SERPINE1/ZYX/PLAT/AIF1L/PLAAT4/GPRC5A/KRT8/KRT18/IGFBP6/OASL/PLEK2/ALDH1A3/COTL1/CAVIN1/GATA6/FXYD5/TGFB1/NECTIN2 | 27 |
| GOBP_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | GOBP_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION | 48/1438 | 352/23056 | 0.1363636 | 2.186370 | 5.784882 | 0.0000003 | 0.0000046 | 0.0000029 | EDN2/MCOLN2/S1PR1/CASQ1/PTPRC/ATP2B4/AGT/ACKR3/ACKR2/CCR3/WNT5A/TRPC3/F2RL1/EDN1/ITPR3/HCRTR2/TRDN/CD36/CAV2/CAV1/TRPA1/ADCY8/GPR20/S1PR3/CCKBR/ADM/SAA1/UBASH3B/KCNA5/C3AR1/TPCN1/TRPC4/EDNRB/PRKD1/SLC24A4/BDKRB1/TRPV2/CCR7/HAP1/C1QTNF1/CACNA1A/C5AR1/FPR1/ADRA1D/PRNP/JPH2/CYSLTR1/LPAR4 | 48 |
| WP_OREXIN_RECEPTOR_PATHWAY | WP_OREXIN_RECEPTOR_PATHWAY | WP_OREXIN_RECEPTOR_PATHWAY | 28/1438 | 154/23056 | 0.1818182 | 2.915160 | 6.150111 | 0.0000003 | 0.0000046 | 0.0000030 | VCAM1/IL1B/BHLHE40/PPARG/PLD1/HES1/DOK7/CXCL8/CXCL2/SPP1/HBEGF/ID4/RUNX2/HCRTR2/TENT5A/LAMA2/CCN2/IL6/KLF4/PAPPA/MMP3/HMGA2/FOS/DIO2/NOG/GADD45B/ICAM1/RUNX1 | 28 |
| GOBP_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 56/1438 | 439/23056 | 0.1275626 | 2.045260 | 5.702870 | 0.0000003 | 0.0000046 | 0.0000030 | AGRN/TNFRSF1B/CRABP2/IL1B/DLX1/DLX2/FN1/EPHA4/SERPINE2/BHLHE40/SEMA3B/WNT5A/MME/IL1RAP/HES1/SLIT2/SPP1/GRID2/VEGFC/SEMA5A/ID4/TNFRSF21/TPBG/THBS2/IL6/GLI3/SEMA3C/SEMA3A/SEMA3D/PTPRZ1/PTN/SHH/PLAG1/NOTCH1/NRP1/DKK1/PITX3/MYRF/YAP1/BHLHE41/AMIGO2/NFATC4/SOX8/TRPV2/HAP1/HOXB3/NOG/MBP/SEMA6B/MAG/TGFB1/BMP2/TGM2/LIF/SRPX2/SLITRK4 | 56 |
| HSIAO_LIVER_SPECIFIC_GENES | HSIAO_LIVER_SPECIFIC_GENES | HSIAO_LIVER_SPECIFIC_GENES | 38/1438 | 249/23056 | 0.1526104 | 2.446861 | 5.920341 | 0.0000003 | 0.0000046 | 0.0000030 | FMO3/CFH/HSD11B1/AGT/HNMT/KYNU/TFPI/AOX1/CPS1/ITIH3/AADAC/CPN2/UGT2B7/CFI/TDO2/C9/FST/CRHBP/PON3/SERPINE1/RARRES2/PTGR1/MBL2/SAA1/NNMT/APOC3/APOA1/C1S/C1R/HPD/PYGL/SERPINA6/SERPINA1/ACSM3/CES1/C3/APOE/IL13RA1 | 38 |
| GOBP_POSITIVE_REGULATION_OF_OSSIFICATION | GOBP_POSITIVE_REGULATION_OF_OSSIFICATION | GOBP_POSITIVE_REGULATION_OF_OSSIFICATION | 15/1438 | 51/23056 | 0.2941176 | 4.715700 | 6.851235 | 0.0000003 | 0.0000047 | 0.0000030 | CCN1/TGFB2/OSR1/WNT5A/ADRB2/BMP6/TFAP2A/TENT5A/FAM20C/PTN/ALOX5/WNT10B/BMP4/TGFB1/BMP2 | 15 |
| GOBP_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | GOBP_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | GOBP_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 15/1438 | 51/23056 | 0.2941176 | 4.715700 | 6.851235 | 0.0000003 | 0.0000047 | 0.0000030 | AGT/WNT5A/GDNF/PDGFA/SHH/SULF1/FGFR2/BMP4/SIX1/SIX4/SOX8/LHX1/HOXB7/NOG/SOX9 | 15 |
| GOBP_STRIATED_MUSCLE_CELL_PROLIFERATION | GOBP_STRIATED_MUSCLE_CELL_PROLIFERATION | GOBP_STRIATED_MUSCLE_CELL_PROLIFERATION | 18/1438 | 72/23056 | 0.2500000 | 4.008345 | 6.593793 | 0.0000003 | 0.0000048 | 0.0000031 | TGFB2/BMP10/TGFBR2/FOXC1/CITED2/SHH/FGF20/ZFPM2/ANGPT1/NOTCH1/FGFR2/YAP1/GLI1/SIX1/NOG/GATA6/SIX5/RUNX1 | 18 |
| HP_AUTOIMMUNE_ANTIBODY_POSITIVITY | HP_AUTOIMMUNE_ANTIBODY_POSITIVITY | HP_AUTOIMMUNE_ANTIBODY_POSITIVITY | 18/1438 | 72/23056 | 0.2500000 | 4.008345 | 6.593793 | 0.0000003 | 0.0000048 | 0.0000031 | GFI1/PTPN22/FCGR2A/CASP10/SPP1/STING1/RHAG/TNFAIP3/TNFSF15/FAS/NFKB2/SLC7A7/MMP2/ELANE/IL12RB1/IL2RB/COL4A6/COL4A5 | 18 |
| GOBP_NEUTROPHIL_MIGRATION | GOBP_NEUTROPHIL_MIGRATION | GOBP_NEUTROPHIL_MIGRATION | 25/1438 | 128/23056 | 0.1953125 | 3.131520 | 6.236852 | 0.0000003 | 0.0000048 | 0.0000031 | EDN2/MCOLN2/TGFB2/IL1R1/IL1A/IL1B/DPP4/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EDN1/CCL26/SAA1/C3AR1/NCKAP1L/CCL5/CCR7/PECAM1/C5AR1/RAC2/XG | 25 |
| DER_IFN_BETA_RESPONSE_UP | DER_IFN_BETA_RESPONSE_UP | DER_IFN_BETA_RESPONSE_UP | 22/1438 | 103/23056 | 0.2135922 | 3.424605 | 6.360543 | 0.0000003 | 0.0000048 | 0.0000031 | GBP1/RHOC/IFI16/NMI/CASP8/SP110/ITGA2/HLA-E/HLA-C/PSMB8/PSMB9/IL6/ADAM9/CEBPD/FOSL1/C1S/OASL/IRF9/PSMB10/IFI35/MX2/MX1 | 22 |
| HUMMERICH_SKIN_CANCER_PROGRESSION_DN | HUMMERICH_SKIN_CANCER_PROGRESSION_DN | HUMMERICH_SKIN_CANCER_PROGRESSION_DN | 22/1438 | 103/23056 | 0.2135922 | 3.424605 | 6.360543 | 0.0000003 | 0.0000048 | 0.0000031 | HSPB7/COL3A1/NRP2/DES/LAMB2/GJA1/GPNMB/ZYX/TPM2/ACSL5/PYGM/SERPINA1/MYH8/MYH4/MYH1/DSG2/C3/BCAM/MYL9/COL6A2/GGT1/LGALS1 | 22 |
| GOBP_HORMONE_METABOLIC_PROCESS | GOBP_HORMONE_METABOLIC_PROCESS | GOBP_HORMONE_METABOLIC_PROCESS | 36/1438 | 230/23056 | 0.1565217 | 2.509572 | 5.934132 | 0.0000003 | 0.0000050 | 0.0000032 | DHRS3/ECE1/RPE65/GFI1/CRABP2/SRD5A2/CYP26B1/DPP4/UGT2B7/SULT1E1/SPP1/DAB2/PCSK1/BMP6/HFE/PLA2G7/DDO/AKR1B10/AKR1B15/SHH/PCSK5/AKR1C3/PAPSS2/CYP26A1/TCF7L2/ADM/EDNRB/DIO2/CYP46A1/CYP19A1/ALDH1A2/ALDH1A3/IL4I1/KLK6/BMP2/BACE2 | 36 |
| REACTOME_SIGNALING_BY_PDGF | REACTOME_SIGNALING_BY_PDGF | REACTOME_SIGNALING_BY_PDGF | 16/1438 | 58/23056 | 0.2758621 | 4.423001 | 6.731786 | 0.0000003 | 0.0000050 | 0.0000032 | COL3A1/COL5A2/COL6A3/SPP1/PDGFC/THBS2/PDGFA/PLAT/COL5A1/STAT6/THBS1/GRB7/COL9A3/COL6A2/PDGFB/COL4A5 | 16 |
| GOBP_ZYMOGEN_ACTIVATION | GOBP_ZYMOGEN_ACTIVATION | GOBP_ZYMOGEN_ACTIVATION | 17/1438 | 65/23056 | 0.2615385 | 4.193346 | 6.649330 | 0.0000003 | 0.0000050 | 0.0000032 | S100A10/IFI16/CASP8/SERPINE2/PERP/SERPINE1/PLAT/ASPH/PLAU/NLRP6/C1R/C1RL/MMP14/THBS1/ANXA2/RUNX1/GGT1 | 17 |
| WP_ENDOCHONDRAL_OSSIFICATION | WP_ENDOCHONDRAL_OSSIFICATION | WP_ENDOCHONDRAL_OSSIFICATION | 17/1438 | 65/23056 | 0.2615385 | 4.193346 | 6.649330 | 0.0000003 | 0.0000050 | 0.0000032 | RUNX3/TGFB2/FGFR3/NKX3-2/SPP1/FGF18/BMP6/RUNX2/SCIN/GLI3/PLAT/PLAU/SERPINH1/IGF1/SOX9/TGFB1/ADAMTS5 | 17 |
| WP_ENDOCHONDRAL_OSSIFICATION_WITH_SKELETAL_DYSPLASIAS | WP_ENDOCHONDRAL_OSSIFICATION_WITH_SKELETAL_DYSPLASIAS | WP_ENDOCHONDRAL_OSSIFICATION_WITH_SKELETAL_DYSPLASIAS | 17/1438 | 65/23056 | 0.2615385 | 4.193346 | 6.649330 | 0.0000003 | 0.0000050 | 0.0000032 | RUNX3/TGFB2/FGFR3/NKX3-2/SPP1/FGF18/BMP6/RUNX2/SCIN/GLI3/PLAT/PLAU/SERPINH1/IGF1/SOX9/TGFB1/ADAMTS5 | 17 |
| GOBP_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | GOBP_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | GOBP_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | 38/1438 | 250/23056 | 0.1520000 | 2.437074 | 5.892217 | 0.0000003 | 0.0000051 | 0.0000032 | ERRFI1/TNFRSF1B/TRIM63/ZC3H12A/EDN2/CASQ1/PTGS2/ATP2B4/AGT/BMP10/PPARG/TNNC1/NPNT/TRPC3/ITGA2/ADRB2/DSP/EDN1/CCN2/CAV1/STC1/FBXO32/NOTCH1/ARHGAP42/TNFRSF1A/SPX/IGF1/FOXO1/TPM1/HCN4/MYOCD/JUP/SGCA/KCNJ2/DSG2/CNN1/MYL9/GATA5 | 38 |
| GOBP_BONE_MINERALIZATION | GOBP_BONE_MINERALIZATION | GOBP_BONE_MINERALIZATION | 24/1438 | 120/23056 | 0.2000000 | 3.206676 | 6.250642 | 0.0000003 | 0.0000051 | 0.0000033 | CCN1/S1PR1/ECM1/PTGS2/OSR1/FGFR3/SGMS2/ADRB2/BMP6/TFAP2A/TENT5A/GJA1/FAM20C/PTN/RSPO2/ALOX5/SRGN/FGFR2/WNT10B/IGF1/BMP4/SOX9/TGFB1/BMP2 | 24 |
| BIDUS_METASTASIS_DN | BIDUS_METASTASIS_DN | BIDUS_METASTASIS_DN | 28/1438 | 155/23056 | 0.1806452 | 2.896352 | 6.109588 | 0.0000003 | 0.0000052 | 0.0000033 | PRRX1/MR1/RNASEL/CD34/GYPC/STAB1/SPON2/SEMA5A/C9/DAB2/AHR/AQP1/CLU/PLEKHA2/FBXO32/GSDMD/PARP10/PGGHG/VWA5A/TNFRSF1A/RND1/SELPLG/TRPV2/GMFG/SIRPA/RIN2/APOL6/TBC1D8B | 28 |
| GOBP_REGULATION_OF_BONE_MINERALIZATION | GOBP_REGULATION_OF_BONE_MINERALIZATION | GOBP_REGULATION_OF_BONE_MINERALIZATION | 19/1438 | 80/23056 | 0.2375000 | 3.807928 | 6.488554 | 0.0000003 | 0.0000053 | 0.0000034 | CCN1/S1PR1/ECM1/OSR1/SGMS2/ADRB2/BMP6/TFAP2A/TENT5A/GJA1/FAM20C/PTN/ALOX5/SRGN/WNT10B/BMP4/SOX9/TGFB1/BMP2 | 19 |
| KERLEY_RESPONSE_TO_CISPLATIN_UP | KERLEY_RESPONSE_TO_CISPLATIN_UP | KERLEY_RESPONSE_TO_CISPLATIN_UP | 14/1438 | 45/23056 | 0.3111111 | 4.988163 | 6.906621 | 0.0000003 | 0.0000053 | 0.0000034 | PLK2/IER3/SERPINE1/CAV1/TNFRSF10C/PLAT/ANXA1/FAS/EPS8L2/FOSL1/DRAM1/ALDH1A3/GDF15/PROCR | 14 |
| SAGIV_CD24_TARGETS_DN | SAGIV_CD24_TARGETS_DN | SAGIV_CD24_TARGETS_DN | 14/1438 | 45/23056 | 0.3111111 | 4.988163 | 6.906621 | 0.0000003 | 0.0000053 | 0.0000034 | ECM1/CXCL8/FOXD1/ADRB2/CAV1/EPHB6/PLAU/OASL/THBS1/ICAM1/GDF15/RELB/EMP3/PDGFB | 14 |
| BHAT_ESR1_TARGETS_VIA_AKT1_UP | BHAT_ESR1_TARGETS_VIA_AKT1_UP | BHAT_ESR1_TARGETS_VIA_AKT1_UP | 41/1438 | 281/23056 | 0.1459075 | 2.339390 | 5.826198 | 0.0000003 | 0.0000054 | 0.0000035 | DHRS3/PADI3/OLFML3/SH2D2A/LONRF2/MLPH/BHLHE40/SEMA3B/FGFRL1/DOK7/IER3/TPBG/TPD52L1/UST/PODXL/PARP12/ZNF703/B4GALT1/CYP26A1/SYT12/ALDH3B1/MYEOV/PGR/VWF/SCNN1A/ZFP36L1/FOS/CA12/OSGIN1/KRT13/KRT15/ADAMTSL5/GADD45B/CYP4F11/GDF15/MAG/KCNK6/TGM2/CDC42EP1/A4GALT/ZNF185 | 41 |
| GOBP_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT | GOBP_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT | GOBP_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT | 12/1438 | 33/23056 | 0.3636364 | 5.830320 | 7.161536 | 0.0000003 | 0.0000054 | 0.0000035 | TGFB2/RARB/CXCL8/GLI3/RARRES2/SHH/PCSK5/FGFR2/ALDH1A2/RBPMS2/SALL1/FOXF1 | 12 |
| GOBP_MESODERMAL_CELL_DIFFERENTIATION | GOBP_MESODERMAL_CELL_DIFFERENTIATION | GOBP_MESODERMAL_CELL_DIFFERENTIATION | 12/1438 | 33/23056 | 0.3636364 | 5.830320 | 7.161536 | 0.0000003 | 0.0000054 | 0.0000035 | ITGA2/GJA1/INHBA/KLF4/ITGA8/DKK1/FGFR2/HMGA2/BMP4/FOXF1/ITGA3/ITGB4 | 12 |
| SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | 23/1438 | 112/23056 | 0.2053571 | 3.292569 | 6.272651 | 0.0000003 | 0.0000054 | 0.0000035 | ERRFI1/PLA2G4A/EFEMP1/DNER/EPHA3/FNDC3B/BCL6/PDGFC/FILIP1/NT5E/SHH/LOXL2/CEBPD/FABP4/FGFR2/AHNAK/ALDH1A3/MAF/SOX9/ITGB4/COLEC12/TFAP2C/COL4A6 | 23 |
| GOBP_REGULATION_OF_BLOOD_CIRCULATION | GOBP_REGULATION_OF_BLOOD_CIRCULATION | GOBP_REGULATION_OF_BLOOD_CIRCULATION | 39/1438 | 261/23056 | 0.1494253 | 2.395792 | 5.848918 | 0.0000004 | 0.0000055 | 0.0000035 | HSPB7/ECE1/ZC3H12A/EDN2/PTGS2/ATP2B4/TGFB2/AGT/BMP10/DES/KCNE4/HRH1/THRB/HBEGF/DSP/EDN1/TBX18/GJA1/TRDN/CCN2/SEMA3A/CAV1/STC1/RNLS/ADM/ARHGAP42/KCNA5/SPX/EDNRB/TPM1/HCN4/MMP2/JUP/MYL4/KCNJ2/DSG2/SCN1B/ADRA1D/CYSLTR1 | 39 |
| GOBP_EMBRYONIC_PLACENTA_DEVELOPMENT | GOBP_EMBRYONIC_PLACENTA_DEVELOPMENT | GOBP_EMBRYONIC_PLACENTA_DEVELOPMENT | 20/1438 | 88/23056 | 0.2272727 | 3.643950 | 6.408955 | 0.0000004 | 0.0000056 | 0.0000036 | CCN1/CASP8/HES1/LEF1/CSF2/MDFI/GCM1/RSPO3/CITED2/FGFR2/PHLDA2/ADM/ZFP36L1/ESRRB/KRT19/SOCS3/CEBPB/LIF/PDGFB/WNT7B | 20 |
| GOBP_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | GOBP_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | GOBP_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS | 20/1438 | 88/23056 | 0.2272727 | 3.643950 | 6.408955 | 0.0000004 | 0.0000056 | 0.0000036 | IL1B/ITIH3/EGF/IL15/CHSY3/UST/CSGALNACT1/ANGPT1/EXT1/HAS2/ST3GAL1/CEMIP2/CD44/EDNRB/B3GNT3/TGFB1/HAS1/PDGFB/CHST7/BGN | 20 |
| TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | 21/1438 | 96/23056 | 0.2187500 | 3.507302 | 6.349076 | 0.0000004 | 0.0000057 | 0.0000037 | CYP4X1/LAMB3/THRB/MYLK/TM4SF18/ANXA3/ITGA2/ID4/PERP/CD36/PDK4/EHF/PGR/BHLHE41/SERPINA1/CGNL1/KRT15/KRT17/CNN1/ADAMTS5/CLIC6 | 21 |
| GOMF_TUMOR_NECROSIS_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | GOMF_TUMOR_NECROSIS_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | GOMF_TUMOR_NECROSIS_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | 7/1438 | 10/23056 | 0.7000000 | 11.223366 | 8.339699 | 0.0000004 | 0.0000057 | 0.0000037 | TNFRSF18/TNFRSF4/TNFRSF1B/FAS/TNFRSF1A/TNFRSF19/TNFRSF11A | 7 |
| HP_CIGARETTE_PAPER_SCARS | HP_CIGARETTE_PAPER_SCARS | HP_CIGARETTE_PAPER_SCARS | 7/1438 | 10/23056 | 0.7000000 | 11.223366 | 8.339699 | 0.0000004 | 0.0000057 | 0.0000037 | COL3A1/COL5A2/COL6A3/COL12A1/COL5A1/COL1A1/COL6A2 | 7 |
| GOBP_VENTRICULAR_SEPTUM_DEVELOPMENT | GOBP_VENTRICULAR_SEPTUM_DEVELOPMENT | GOBP_VENTRICULAR_SEPTUM_DEVELOPMENT | 18/1438 | 73/23056 | 0.2465753 | 3.953436 | 6.518383 | 0.0000004 | 0.0000058 | 0.0000037 | CCN1/TGFB2/XIRP2/TGFBR2/WNT5A/HEG1/HES1/FGFRL1/SLIT2/CITED2/FZD1/ZFPM2/NOTCH1/FGFR2/BMP4/SMAD6/SALL1/NOG | 18 |
| HP_ABNORMALITY_OF_THE_PLANTAR_SKIN_OF_FOOT | HP_ABNORMALITY_OF_THE_PLANTAR_SKIN_OF_FOOT | HP_ABNORMALITY_OF_THE_PLANTAR_SKIN_OF_FOOT | 32/1438 | 193/23056 | 0.1658031 | 2.658384 | 5.966937 | 0.0000004 | 0.0000058 | 0.0000037 | TNFRSF1B/PTCH2/NEXN/KCNN3/LAMC2/LAMB3/DES/COL7A1/TNNC1/SLCO2A1/DSP/CAP2/LAMA4/GJA1/PERP/SASH1/COL14A1/MYPN/VCL/ANKRD1/BAG3/FGFR2/CRYAB/C1R/ACTC1/TPM1/KRT17/JUP/ITGB4/RHBDF2/DSG2/SERPINB7 | 32 |
| CHANDRAN_METASTASIS_DN | CHANDRAN_METASTASIS_DN | CHANDRAN_METASTASIS_DN | 44/1438 | 313/23056 | 0.1405751 | 2.253894 | 5.760541 | 0.0000004 | 0.0000058 | 0.0000037 | FUCA1/PODN/NEXN/PIFO/PRRX1/PTGS2/DPP4/CYBRD1/ITGA4/TWIST2/PRICKLE2/EPHA3/MYLK/CTSO/PDGFC/IQGAP2/RBM24/MICA/CCN2/MOXD1/ITGB8/GLI3/SEMA3C/CAV2/PTN/EPHB6/KLF4/COL13A1/PYROXD2/FGFR2/PAMR1/EFEMP2/BMP4/FOS/AHNAK2/RRAD/CRISPLD2/KRT15/ZFP36/KCNN4/RRAS/MX1/MN1/MXRA5 | 44 |
| HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | 41/1438 | 282/23056 | 0.1453901 | 2.331094 | 5.800534 | 0.0000004 | 0.0000058 | 0.0000037 | S100A11/KCNN3/IFI16/NIBAN1/PTPRC/RASGRP3/ITGA4/BHLHE40/ITGB5/FGFR3/JCHAIN/SLC7A11/IQGAP2/CCDC69/GJA1/TNS3/SULF1/CCN4/FAS/BAG3/HBD/ALDH3B1/SERPINH1/CASP1/STAT6/NUAK1/SELPLG/DNAJC15/IL21R/PSMB10/MAF/SLC47A1/FMNL1/COPZ2/IL27RA/GDF15/FXYD5/BCL3/CEBPB/GGT1/HMOX1 | 41 |
| DELACROIX_RARG_BOUND_MEF | DELACROIX_RARG_BOUND_MEF | DELACROIX_RARG_BOUND_MEF | 49/1438 | 367/23056 | 0.1335150 | 2.140696 | 5.681326 | 0.0000004 | 0.0000063 | 0.0000040 | TNFRSF9/DHRS3/RHOC/CRABP2/NID1/OSR1/LTBP1/AOX1/FN1/BHLHE40/RARB/FSTL1/PLSCR2/TM4SF1/WWTR1/EREG/FGF18/CCN2/PDLIM2/LOXL2/SULF1/TNFRSF11B/TPM2/ANXA1/NRP1/FGFR2/EPS8L2/YAP1/GPRC5A/EMP1/WNT10B/TNS2/NID2/CA12/SMAD6/LOXL1/MSLN/TNFRSF12A/NUPR1/MMP2/COL1A1/C1QTNF1/GDF15/RRAS/RIN2/CEBPB/CARD10/CSDC2/SAT1 | 49 |
| HP_ABNORMALITY_OF_THE_LYMPH_NODES | HP_ABNORMALITY_OF_THE_LYMPH_NODES | HP_ABNORMALITY_OF_THE_LYMPH_NODES | 34/1438 | 213/23056 | 0.1596244 | 2.559319 | 5.896610 | 0.0000004 | 0.0000064 | 0.0000041 | TNFRSF1B/PTPN22/PTPRC/NLRP3/NABP1/CASP10/CASP8/SP110/TGFBR2/BCL6/ADAMTS3/SPP1/FAT4/IL7R/STING1/PSMB8/PSMB9/STX11/IL6/FAS/NFKB2/WT1/BIRC3/APOA1/TNFRSF1A/NCKAP1L/LAT/ELANE/CD70/IL12RB1/APOE/RUNX1/IL2RB/RAC2 | 34 |
| GOBP_PANCREAS_DEVELOPMENT | GOBP_PANCREAS_DEVELOPMENT | GOBP_PANCREAS_DEVELOPMENT | 19/1438 | 81/23056 | 0.2345679 | 3.760916 | 6.419811 | 0.0000004 | 0.0000064 | 0.0000041 | ILDR2/NR5A2/WNT5A/HES1/NKX3-2/PCSK1/BMP6/IL6/MET/SHH/ANXA1/TCF7L2/BMP4/ALDH1A2/MSLN/FOXF1/GIP/SOX9/GATA6 | 19 |
| GOBP_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | GOBP_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | GOBP_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | 29/1438 | 166/23056 | 0.1746988 | 2.801012 | 6.006231 | 0.0000004 | 0.0000065 | 0.0000042 | CASQ1/CYP26B1/VAMP5/DNER/FOXL2/FGFRL1/MYOZ2/RBM24/COL19A1/CITED2/CAV2/CAV1/SHH/MSC/NOTCH1/MYOZ1/ANKRD1/TLL2/WT1/YBX3/WNT10B/ITGA7/SIX1/SIX4/FOS/SOX8/NUPR1/MYOCD/TGFB1 | 29 |
| GOBP_REPLACEMENT_OSSIFICATION | GOBP_REPLACEMENT_OSSIFICATION | GOBP_REPLACEMENT_OSSIFICATION | 11/1438 | 28/23056 | 0.3928571 | 6.298828 | 7.235773 | 0.0000004 | 0.0000066 | 0.0000042 | FGFR3/FGF18/FOXC1/BMP6/RUNX2/CSGALNACT1/EXT1/COL13A1/MMP14/BMP4/COL1A1 | 11 |
| SAFFORD_T_LYMPHOCYTE_ANERGY | SAFFORD_T_LYMPHOCYTE_ANERGY | SAFFORD_T_LYMPHOCYTE_ANERGY | 20/1438 | 89/23056 | 0.2247191 | 3.603007 | 6.345596 | 0.0000004 | 0.0000067 | 0.0000043 | TNFRSF4/CSF1/S100A5/AGT/IER3/DDR1/STX11/MYL7/NOTCH1/SRGN/CASP4/MPZL2/TNFRSF19/ZFP36L1/MYO1E/KIFC3/JUP/GADD45B/TNFSF9/LPAR4 | 20 |
| HP_NEPHRITIS | HP_NEPHRITIS | HP_NEPHRITIS | 21/1438 | 97/23056 | 0.2164948 | 3.471144 | 6.290160 | 0.0000004 | 0.0000068 | 0.0000043 | PTPN22/FCGR2A/CASP10/COL7A1/MME/ARHGAP24/SPP1/CFI/CRB2/FAS/WT1/EFEMP2/MMP1/SLC7A7/FBLN5/MYO1E/C3/APOL1/MYH9/TBC1D8B/COL4A5 | 21 |
| BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN | BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN | BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN | 14/1438 | 46/23056 | 0.3043478 | 4.879724 | 6.793221 | 0.0000005 | 0.0000070 | 0.0000045 | TNFRSF1B/CD34/TGFBR2/ALDH1L1/PDK4/CAV1/FABP4/NECAB1/TEK/MMP3/VWF/IGF1/PECAM1/ABCA6 | 14 |
| GOBP_RESPONSE_TO_EXTRACELLULAR_STIMULUS | GOBP_RESPONSE_TO_EXTRACELLULAR_STIMULUS | GOBP_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 59/1438 | 479/23056 | 0.1231733 | 1.974884 | 5.560858 | 0.0000005 | 0.0000070 | 0.0000045 | ZC3H12A/VCAM1/IFI16/PTGS2/PTPRC/NUAK2/MAP1LC3C/SRD5A2/CYP26B1/IL1A/SCTR/KYNU/ITGA4/CPS1/PPARG/TGFBR2/UCN2/SPP1/IL15/ITGA2/PCSK1/ADRB2/HFE/SOD2/PDK4/STC1/TNFRSF11B/GSDMD/AQP3/AKR1C3/FAS/CYP26A1/ADM/FOSL1/SPX/NUAK1/LRCOL1/POSTN/FOXO1/DNAJC15/PRKD1/FOS/ALDH1A2/NQO1/CD68/MYH13/MYOCD/GIP/COL1A1/WIPI1/LIPG/GDF15/ZFP36/AXL/APOE/CYP24A1/MN1/GAS2L1/HMOX1 | 59 |
| GOBP_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | GOBP_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | GOBP_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | 34/1438 | 214/23056 | 0.1588785 | 2.547359 | 5.865233 | 0.0000005 | 0.0000071 | 0.0000045 | OSR1/BHLHE40/WNT5A/HES1/LEF1/FOXC1/TDRD6/TBX18/HOXA2/HOXA3/HOXA7/GLI3/SEMA3C/SHH/DMRT2/PCSK5/CRB2/NOTCH1/DKK1/HHEX/WT1/ALX4/BHLHE41/BMP4/ALDH1A2/FOXB1/FOXF1/LHX1/MEOX1/HOXB2/HOXB3/HOXB7/NOG/BMP2 | 34 |
| GOBP_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | 10/1438 | 23/23056 | 0.4347826 | 6.971035 | 7.389116 | 0.0000005 | 0.0000071 | 0.0000046 | PRRX1/TGFBR2/WNT5A/KDR/PDGFA/SHH/FGFR2/SIX1/FOXF1/SOX9 | 10 |
| GOBP_POSITIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 30/1438 | 176/23056 | 0.1704545 | 2.732962 | 5.952121 | 0.0000005 | 0.0000071 | 0.0000046 | RHOC/S100A10/LMOD1/BMP10/SEMA5A/F2RL1/EDN1/CCN2/SCIN/CCL26/MET/LMOD2/ARHGEF5/CLU/GSN/NRP1/SYNPO2L/EFEMP2/APOA1/NCKAP1L/NAV3/TPM1/MYLK3/CSF3/CCR7/APOE/CDC42EP5/SDC4/CDC42EP1/TENM1 | 30 |
| GOBP_PLATELET_ACTIVATION | GOBP_PLATELET_ACTIVATION | GOBP_PLATELET_ACTIVATION | 25/1438 | 131/23056 | 0.1908397 | 3.059805 | 6.097635 | 0.0000005 | 0.0000072 | 0.0000047 | PLA2G4A/COL3A1/FN1/SERPINE2/TXK/TEC/SLC7A11/TREML1/PDGFA/IL6/FZD6/VCL/TSPAN32/SAA1/UBASH3B/VWF/ADAMTS18/C1QTNF1/EMILIN2/AXL/APOE/THBD/MYL9/MYH9/PDGFB | 25 |
| WP_ADIPOGENESIS | WP_ADIPOGENESIS | WP_ADIPOGENESIS | 25/1438 | 131/23056 | 0.1908397 | 3.059805 | 6.097635 | 0.0000005 | 0.0000072 | 0.0000047 | AGT/CYP26B1/PPARG/WWTR1/BMP3/AHR/IL6/FZD1/SERPINE1/CEBPD/FAS/CYP26A1/WNT10B/STAT6/IGF1/FOXO1/BMP4/SOCS3/GADD45B/TGFB1/BMP2/PTGIS/CEBPB/LIF/PNPLA3 | 25 |
| GOBP_EXTRACELLULAR_MATRIX_CONSTITUENT_SECRETION | GOBP_EXTRACELLULAR_MATRIX_CONSTITUENT_SECRETION | GOBP_EXTRACELLULAR_MATRIX_CONSTITUENT_SECRETION | 8/1438 | 14/23056 | 0.5714286 | 9.161931 | 7.878637 | 0.0000005 | 0.0000073 | 0.0000047 | TNFRSF1B/AGT/ADTRP/CCN2/NOTCH1/CREB3L1/TNFRSF1A/BMP2 | 8 |
| GOBP_ANATOMICAL_STRUCTURE_MATURATION | GOBP_ANATOMICAL_STRUCTURE_MATURATION | GOBP_ANATOMICAL_STRUCTURE_MATURATION | 37/1438 | 244/23056 | 0.1516393 | 2.431291 | 5.796896 | 0.0000005 | 0.0000073 | 0.0000047 | AGRN/S1PR1/TGFB2/PPARG/WNT5A/HES1/FGFR3/KDR/EREG/IL15/ADAMTS12/EDN1/TCP11/RUNX2/TDRD6/GJA1/FAM20C/EXT1/PAEP/PGR/RND1/WNT10B/IGF1/EDNRB/SLC24A4/EPB42/GLDN/ALDH1A2/BNC1/SOX8/MMP2/HOXB13/C3/KLF2/AXL/BMP2/BFSP1 | 37 |
| HP_LIPODYSTROPHY | HP_LIPODYSTROPHY | HP_LIPODYSTROPHY | 23/1438 | 114/23056 | 0.2017544 | 3.234805 | 6.169225 | 0.0000005 | 0.0000073 | 0.0000047 | FUCA1/NEXN/COL3A1/DES/PPARG/TNNC1/DSP/CAP2/PSMB8/PSMB9/LAMA4/CAV1/MYPN/VCL/ANKRD1/BAG3/CRYAB/FOS/ACTC1/FBN1/TPM1/CAVIN1/DSG2 | 23 |
| SABATES_COLORECTAL_ADENOMA_UP | SABATES_COLORECTAL_ADENOMA_UP | SABATES_COLORECTAL_ADENOMA_UP | 26/1438 | 140/23056 | 0.1857143 | 2.977628 | 6.053317 | 0.0000005 | 0.0000074 | 0.0000048 | CYP4X1/S100A11/S100A2/CPS1/CLDN1/CXCL8/CXCL1/CXCL3/CXCL2/CCNO/PCSK1/TGFBI/SH3TC2/INHBA/TNFRSF10C/CD44/MMP10/MMP1/MMP3/KRT80/FREM2/AJUBA/MSLN/NQO1/BACE2/SRPX2 | 26 |
| GOZGIT_ESR1_TARGETS_UP | GOZGIT_ESR1_TARGETS_UP | GOZGIT_ESR1_TARGETS_UP | 27/1438 | 149/23056 | 0.1812081 | 2.905378 | 6.017891 | 0.0000005 | 0.0000075 | 0.0000048 | ECM1/ADAMTSL4/PPARG/PLD1/SEMA5A/TFAP2A/COL21A1/COL12A1/NT5E/SERPINE1/ASPH/GAS1/ALOX5/ANXA8/MMRN2/CYP26A1/ACSL5/TCF7L2/MICAL2/ALDH3B1/FOS/GRAMD2A/ANPEP/CRISPLD2/ACSF2/PECAM1/SLC16A5 | 27 |
| PETRETTO_CARDIAC_HYPERTROPHY | PETRETTO_CARDIAC_HYPERTROPHY | PETRETTO_CARDIAC_HYPERTROPHY | 12/1438 | 34/23056 | 0.3529412 | 5.658840 | 7.011323 | 0.0000005 | 0.0000076 | 0.0000049 | NID1/CRIM1/EFEMP1/COL5A2/FN1/FSTL1/TM4SF1/ANXA1/CD44/TAGLN/FBN1/LOXL1 | 12 |
| SCHRAETS_MLL_TARGETS_DN | SCHRAETS_MLL_TARGETS_DN | SCHRAETS_MLL_TARGETS_DN | 12/1438 | 34/23056 | 0.3529412 | 5.658840 | 7.011323 | 0.0000005 | 0.0000076 | 0.0000049 | CD53/COL6A3/TWIST2/MGLL/TGFBI/THBS2/RSPO2/GAS1/ARHGDIB/GATA6/THBD/COL6A2 | 12 |
| BROWNE_HCMV_INFECTION_2HR_UP | BROWNE_HCMV_INFECTION_2HR_UP | BROWNE_HCMV_INFECTION_2HR_UP | 13/1438 | 40/23056 | 0.3250000 | 5.210848 | 6.874465 | 0.0000005 | 0.0000076 | 0.0000049 | DHRS3/CXCL8/CXCL3/COL21A1/RARRES2/MAP3K8/VWA5A/NFKBIA/FOS/ELANE/ICAM1/APOE/SSX2 | 13 |
| KRASNOSELSKAYA_ILF3_TARGETS_UP | KRASNOSELSKAYA_ILF3_TARGETS_UP | KRASNOSELSKAYA_ILF3_TARGETS_UP | 13/1438 | 40/23056 | 0.3250000 | 5.210848 | 6.874465 | 0.0000005 | 0.0000076 | 0.0000049 | IFI16/CFH/FAP/CTSO/HLA-E/PSMB9/NT5E/PLAU/EMP1/IFI35/APOE/MX2/MX1 | 13 |
| TOMLINS_PROSTATE_CANCER_DN | TOMLINS_PROSTATE_CANCER_DN | TOMLINS_PROSTATE_CANCER_DN | 13/1438 | 40/23056 | 0.3250000 | 5.210848 | 6.874465 | 0.0000005 | 0.0000076 | 0.0000049 | ATP2B4/MYLK/LAMA4/CLU/RBPMS/TPM2/GAS1/GSN/VCL/MYOF/CAVIN1/ITGB4/CNN1 | 13 |
| WP_VITAMIN_D_RECEPTOR_PATHWAY | WP_VITAMIN_D_RECEPTOR_PATHWAY | WP_VITAMIN_D_RECEPTOR_PATHWAY | 31/1438 | 186/23056 | 0.1666667 | 2.672230 | 5.905731 | 0.0000005 | 0.0000076 | 0.0000049 | S100A2/TGFB2/SULT1C2/DNER/SEMA3B/GXYLT2/BCL6/SLC34A2/SPP1/ADRB2/SERPINB1/BMP6/ID4/TNFAIP3/EPHB4/PNOC/TNFRSF11B/KLF4/ALOX5/COL13A1/FOXO1/BDKRB1/TPM1/KRT13/TGFB1/KLK6/THBD/NFATC2/CYP24A1/ADAMTS5/MX2 | 31 |
| GOBP_STRIATED_MUSCLE_CELL_DEVELOPMENT | GOBP_STRIATED_MUSCLE_CELL_DEVELOPMENT | GOBP_STRIATED_MUSCLE_CELL_DEVELOPMENT | 17/1438 | 67/23056 | 0.2537313 | 4.068171 | 6.486511 | 0.0000005 | 0.0000076 | 0.0000049 | CASQ1/LMOD1/BMP10/MYOZ2/EDN1/LMOD2/FLNC/MYPN/MYOZ1/SYNPO2L/ANKRD1/SIX4/ACTC1/TPM1/MYLK3/KRT19/MYL9 | 17 |
| WP_OVERLAP_BETWEEN_SIGNAL_TRANSDUCTION_PATHWAYS_CONTRIBUTING_TO_LMNA_LAMINOPATHIES | WP_OVERLAP_BETWEEN_SIGNAL_TRANSDUCTION_PATHWAYS_CONTRIBUTING_TO_LMNA_LAMINOPATHIES | WP_OVERLAP_BETWEEN_SIGNAL_TRANSDUCTION_PATHWAYS_CONTRIBUTING_TO_LMNA_LAMINOPATHIES | 16/1438 | 60/23056 | 0.2666667 | 4.275568 | 6.552248 | 0.0000005 | 0.0000079 | 0.0000051 | TGFB2/PPARG/HES1/SPP1/LEF1/RUNX2/CEBPD/TNFRSF11B/NOTCH1/TCF7L2/WNT10B/HMGA2/TGFB1/BMP2/CEBPB/WNT7B | 16 |
| HP_SUBCUTANEOUS_HEMORRHAGE | HP_SUBCUTANEOUS_HEMORRHAGE | HP_SUBCUTANEOUS_HEMORRHAGE | 35/1438 | 225/23056 | 0.1555556 | 2.494081 | 5.808410 | 0.0000005 | 0.0000079 | 0.0000051 | PTPN22/CFH/TGFB2/NLRP3/COL3A1/COL5A2/NABP1/CASP10/TGFBR2/MYLK/ITGA2/ADAMTS2/RREB1/CD109/TENT5A/STX11/SAMD9/SERPINE1/GSN/COL5A1/PLAU/FAS/NFKB2/VWF/TNFRSF1A/C1S/C1R/FBN1/COL1A1/APOE/RIN2/RUNX1/USP18/MYH9/PDGFB | 35 |
| CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | 60/1438 | 493/23056 | 0.1217039 | 1.951324 | 5.506908 | 0.0000006 | 0.0000083 | 0.0000053 | FUCA1/LDLRAP1/S100A13/NIBAN1/IL1R1/RPRM/GALNT3/AOX1/ACKR3/PRICKLE2/PHLDB2/CCDC80/MGLL/FAM114A1/ANXA3/CDS1/SGMS2/GASK1B/PLK2/ELL2/GRAMD2B/GALNT10/RNF144B/FILIP1/UTRN/SASH1/SYNJ2/FAM20C/MAFK/AHR/ADAM9/LRATD2/ST3GAL1/AQP3/GSN/NACC2/PTPRJ/FZD4/MPZL2/EMP1/DRAM1/RAB20/THBS1/LOXL1/ALDH1A3/RHBDF1/COPZ2/WIPI1/COLEC12/GATA6/GDF15/ZFP36/BCAM/RIN2/NCAM2/SIM2/MYH9/KDELR3/SAT1/IL13RA1 | 60 |
| GOMF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOMF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOMF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 26/1438 | 141/23056 | 0.1843972 | 2.956510 | 6.010158 | 0.0000006 | 0.0000085 | 0.0000055 | EPHA2/TIE1/CRIM1/EFEMP1/NRP2/EPHA4/EPHA3/FGFRL1/FGFR3/TXK/TEC/KDR/DDR1/ROS1/EPHB4/MET/EPHB6/PDGFRL/TEK/NRP1/FGFR2/STYK1/FLT3/FLT1/LTK/AXL | 26 |
| GOBP_MYELOID_CELL_DIFFERENTIATION | GOBP_MYELOID_CELL_DIFFERENTIATION | GOBP_MYELOID_CELL_DIFFERENTIATION | 51/1438 | 393/23056 | 0.1297710 | 2.080668 | 5.572935 | 0.0000006 | 0.0000085 | 0.0000055 | EPHA2/CSF1/IFI16/RAB7B/ITPKB/ITGB6/CASP8/PPARG/TGFBR2/MITF/BCL6/LEF1/IL15/TLR3/IL31RA/F2RL1/CSF2/ADGRF5/RHAG/CD109/CITED2/FAM20C/SCIN/ITGB8/HOXA7/INHBA/CCN4/UBASH3B/NCKAP1L/NFKBIA/BMP4/ZFP36L1/FOS/EPB42/FBN1/ANXA2/CSF3/CCR7/HOXB7/SIGLEC15/TNFRSF11A/FSTL3/KLF2/ZFP36/TGFB1/RELB/IL11/CEBPB/RUNX1/LIF/MYH9 | 51 |
| GOBP_MESODERM_MORPHOGENESIS | GOBP_MESODERM_MORPHOGENESIS | GOBP_MESODERM_MORPHOGENESIS | 18/1438 | 75/23056 | 0.2400000 | 3.848011 | 6.371506 | 0.0000006 | 0.0000086 | 0.0000055 | EPHA2/WNT5A/LEF1/ITGA2/FOXC1/GJA1/INHBA/KLF4/CRB2/ITGA8/DKK1/FGFR2/HMGA2/BMP4/FOXF1/ITGA3/NOG/ITGB4 | 18 |
| GOBP_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | 18/1438 | 75/23056 | 0.2400000 | 3.848011 | 6.371506 | 0.0000006 | 0.0000086 | 0.0000055 | TNFRSF1B/DLX1/DLX2/EPHA4/SERPINE2/HES1/ID4/TNFRSF21/IL6/PTPRZ1/PTN/SHH/NOTCH1/NOG/MAG/TGFB1/BMP2/LIF | 18 |
| MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | 47/1438 | 350/23056 | 0.1342857 | 2.153054 | 5.606186 | 0.0000006 | 0.0000088 | 0.0000056 | PODN/WNT9A/EVA1A/NPAS2/VIPR1/SOWAHB/NPR3/GDNF/MCIDAS/ANKRD34B/PRDM6/ADAMTS2/BMP6/SIM1/AHR/SLC26A4/CADPS2/MSC/DMRT2/PAPPA/FIBCD1/COL13A1/HTR7/CYP26A1/HMX3/PHLDA2/AHNAK/SYT12/AMIGO2/FLT3/LTBP2/ALDH1A2/BNC1/FOXF1/DLX3/ITGA3/NOG/COLEC12/GATA6/TGFB1/NPAS1/KCNA7/NFATC2/SIM2/PDGFB/A4GALT/CELSR1 | 47 |
| GOBP_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | GOBP_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | GOBP_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 60/1438 | 494/23056 | 0.1214575 | 1.947374 | 5.489723 | 0.0000006 | 0.0000088 | 0.0000057 | AGRN/EPHA2/TRABD2B/GBP5/RHOC/S100A10/LMOD1/AGT/TRABD2A/CAPG/PHLDB2/CLDN1/IL1RAP/KDR/GRID2/F2RL1/CSF2/TPBG/CCN2/THBS2/CCL26/CD36/CAV1/MET/LMOD2/ARHGEF5/CLU/TEK/NRP1/SYNPO2L/EPS8L2/PTPRJ/MMP1/MMP3/APOA1/EPS8/AMIGO2/WNT10B/NCKAP1L/NAV3/LCP1/AJUBA/PLEK2/BMF/TPM1/PIEZO1/CSF3/CCR7/HAP1/WIPI1/SOX9/TGFB1/CDC42EP5/SDC4/RAC2/CDC42EP1/MSN/SRPX2/TENM1/SLITRK4 | 60 |
| GOBP_MYOTUBE_DIFFERENTIATION | GOBP_MYOTUBE_DIFFERENTIATION | GOBP_MYOTUBE_DIFFERENTIATION | 24/1438 | 124/23056 | 0.1935484 | 3.103235 | 6.056642 | 0.0000006 | 0.0000091 | 0.0000059 | CD53/CYP26B1/DNER/RBM24/CAV2/SHH/NOTCH1/MYOF/ADAMTS15/BHLHE41/WNT10B/IGF1/MMP14/SIX1/SIX4/IL4R/PIEZO1/MYOCD/TNFSF14/GDF15/EHD2/NFATC2/ADAMTS5/MYH9 | 24 |
| TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | 20/1438 | 91/23056 | 0.2197802 | 3.523820 | 6.221571 | 0.0000006 | 0.0000095 | 0.0000061 | CYP4X1/LAMB3/ACTG2/GALNT3/MYLK/TM4SF18/ITGA2/ID4/PERP/FAM126A/PDK4/SAA1/EHF/SERPINA6/CGNL1/KRT15/KRT17/CNN1/CLIC6/ITM2A | 20 |
| KEGG_CELL_ADHESION_MOLECULES_CAMS | KEGG_CELL_ADHESION_MOLECULES_CAMS | KEGG_CELL_ADHESION_MOLECULES_CAMS | 25/1438 | 133/23056 | 0.1879699 | 3.013793 | 6.007022 | 0.0000006 | 0.0000095 | 0.0000061 | VCAM1/PTPRC/CD34/ITGA6/ITGA4/CLDN1/CLDN16/HLA-E/HLA-C/ITGB8/CD274/PDCD1LG2/ITGA8/SELPLG/CLDN6/CDH15/CLDN7/PECAM1/ICAM1/MAG/CD22/NECTIN2/SDC4/NCAM2/ICOSLG | 25 |
| GOMF_ACTIN_FILAMENT_BINDING | GOMF_ACTIN_FILAMENT_BINDING | GOMF_ACTIN_FILAMENT_BINDING | 34/1438 | 217/23056 | 0.1566820 | 2.512142 | 5.772159 | 0.0000006 | 0.0000095 | 0.0000061 | NEXN/CAPG/XIRP2/XIRP1/TNNC1/MYO10/IQGAP2/ABLIM3/UTRN/MICALL2/SCIN/FLNC/TPM2/GSN/AIF1L/ANXA8/TAGLN/LCP1/AJUBA/MYO1E/TPM1/COTL1/MYH13/MYH8/MYH4/MYH1/MYH2/FMNL1/MYL4/MYOM1/GAS2L1/MYH9/PLS3/ZNF185 | 34 |
| BIOCARTA_INFLAM_PATHWAY | BIOCARTA_INFLAM_PATHWAY | BIOCARTA_INFLAM_PATHWAY | 11/1438 | 29/23056 | 0.3793103 | 6.081627 | 7.062156 | 0.0000007 | 0.0000096 | 0.0000061 | CSF1/TGFB2/IL1A/CXCL8/IL15/CSF2/PDGFA/IL6/CSF3/TGFB1/IL11 | 11 |
| BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | BOYAULT_LIVER_CANCER_SUBCLASS_G5_DN | 11/1438 | 29/23056 | 0.3793103 | 6.081627 | 7.062156 | 0.0000007 | 0.0000096 | 0.0000061 | S100A11/IFI16/SEL1L3/C9/DAB2/ARHGDIB/ICAM1/BCL3/EMP3/SIRPA/TGM2 | 11 |
| GOBP_CRANIAL_NERVE_MORPHOGENESIS | GOBP_CRANIAL_NERVE_MORPHOGENESIS | GOBP_CRANIAL_NERVE_MORPHOGENESIS | 11/1438 | 29/23056 | 0.3793103 | 6.081627 | 7.062156 | 0.0000007 | 0.0000096 | 0.0000061 | NRP2/TFAP2A/CITED2/HOXA1/HOXA3/GLI3/SEMA3A/NRP1/SIX1/HOXB2/HOXB3 | 11 |
| GOBP_REGULATION_OF_ANIMAL_ORGAN_FORMATION | GOBP_REGULATION_OF_ANIMAL_ORGAN_FORMATION | GOBP_REGULATION_OF_ANIMAL_ORGAN_FORMATION | 11/1438 | 29/23056 | 0.3793103 | 6.081627 | 7.062156 | 0.0000007 | 0.0000096 | 0.0000061 | WNT5A/GDNF/CITED2/SHH/SULF1/DKK1/WT1/BMP4/SIX1/BMP2/GATA5 | 11 |
| GOBP_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | GOBP_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | GOBP_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | 11/1438 | 29/23056 | 0.3793103 | 6.081627 | 7.062156 | 0.0000007 | 0.0000096 | 0.0000061 | PRRX1/TGFBR2/WNT5A/KDR/PDGFA/SHH/FGFR2/BMP4/SIX1/FOXF1/SOX9 | 11 |
| GOBP_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 26/1438 | 142/23056 | 0.1830986 | 2.935689 | 5.967379 | 0.0000007 | 0.0000096 | 0.0000062 | WNT5A/WWTR1/NKD2/DAB2/TPBG/TBX18/GLI3/HECW1/FZD1/CAV1/SHH/FZD6/CTHRC1/NOTCH1/DKK1/TCF7L2/FZD4/IGFBP6/GLI1/LATS2/FOXO1/DACT1/NOG/SOX9/APOE/BMP2 | 26 |
| GOBP_REGULATION_OF_FAT_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_FAT_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 26/1438 | 142/23056 | 0.1830986 | 2.935689 | 5.967379 | 0.0000007 | 0.0000096 | 0.0000062 | ZC3H12A/PTGS2/PPARG/WNT5A/WWTR1/HES1/SULT1E1/CDS1/RREB1/ID4/SOD2/IL6/RARRES2/ZFPM2/CCN4/ALOX5/YAP1/WNT10B/FOXO1/SIX1/ZFP36L1/METRNL/ZFP36/TGFB1/BMP2/CEBPB | 26 |
| YAMASHITA_METHYLATED_IN_PROSTATE_CANCER | YAMASHITA_METHYLATED_IN_PROSTATE_CANCER | YAMASHITA_METHYLATED_IN_PROSTATE_CANCER | 16/1438 | 61/23056 | 0.2622951 | 4.205477 | 6.465395 | 0.0000007 | 0.0000099 | 0.0000063 | S100A5/TFPI/ACKR3/TM4SF1/SLC34A2/PLAC8/SPP1/SPARC/GPNMB/SERPINE1/ANKRD1/MMP10/TAGLN/TRPV2/COL1A1/KLK6 | 16 |
| GOBP_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE | 30/1438 | 179/23056 | 0.1675978 | 2.687159 | 5.844362 | 0.0000007 | 0.0000100 | 0.0000064 | ZC3H12A/IFI16/PTPRC/NMI/COL3A1/PPARG/CD96/PARP14/BCL6/IL7R/PLK2/HFE/HLA-E/MICA/TNFAIP3/AHR/ANXA1/NLRP6/KLRD1/NCKAP1L/STAT6/IL4R/NLRC5/FOXF1/DHX58/RHBDF2/IL27RA/IL4I1/USP18/HMOX1 | 30 |
| GOBP_MESENCHYMAL_CELL_PROLIFERATION | GOBP_MESENCHYMAL_CELL_PROLIFERATION | GOBP_MESENCHYMAL_CELL_PROLIFERATION | 13/1438 | 41/23056 | 0.3170732 | 5.083755 | 6.749946 | 0.0000007 | 0.0000102 | 0.0000065 | PRRX1/OSR1/TGFBR2/WNT5A/KDR/PDGFA/SHH/FGFR2/BMP4/SIX1/FOXF1/SOX9/BMP2 | 13 |
| ZHU_CMV_8_HR_UP | ZHU_CMV_8_HR_UP | ZHU_CMV_8_HR_UP | 13/1438 | 41/23056 | 0.3170732 | 5.083755 | 6.749946 | 0.0000007 | 0.0000102 | 0.0000065 | GBP1/PTGS2/PLA2G4A/SP100/HLA-E/PSMB8/TNFAIP3/IL6/IDO1/CCL5/IL11/MX2/MX1 | 13 |
| GOBP_REGULATION_OF_HEMOPOIESIS | GOBP_REGULATION_OF_HEMOPOIESIS | GOBP_REGULATION_OF_HEMOPOIESIS | 49/1438 | 374/23056 | 0.1310160 | 2.100630 | 5.534657 | 0.0000007 | 0.0000105 | 0.0000067 | RUNX3/ZC3H12A/CSF1/PTPRC/RAB7B/ITPKB/NLRP3/CYP26B1/CASP8/TGFBR2/MITF/BCL6/LEF1/IL15/TLR3/IL7R/VNN1/SCIN/HOXA7/INHBA/GLI3/PTN/SHH/TCIM/ANXA1/IL15RA/UBASH3B/NCKAP1L/TESPA1/MMP14/NFKBIA/BMP4/ZFP36L1/FOS/FBN1/IL4R/CSF3/FSTL3/TNFSF9/IL12RB1/ZFP36/AXL/TGFB1/PSG9/IL4I1/CEBPB/RUNX1/LIF/LGALS1 | 49 |
| VALK_AML_CLUSTER_9 | VALK_AML_CLUSTER_9 | VALK_AML_CLUSTER_9 | 12/1438 | 35/23056 | 0.3428571 | 5.497159 | 6.866958 | 0.0000007 | 0.0000105 | 0.0000067 | DHRS3/RUNX3/MTMR11/MGLL/TGFBI/SPARC/NT5E/NRP1/PAPSS2/MSLN/COLEC12/MN1 | 12 |
| WANG_METHYLATED_IN_BREAST_CANCER | WANG_METHYLATED_IN_BREAST_CANCER | WANG_METHYLATED_IN_BREAST_CANCER | 12/1438 | 35/23056 | 0.3428571 | 5.497159 | 6.866958 | 0.0000007 | 0.0000105 | 0.0000067 | EPHA2/HBEGF/INHBA/CAV1/ZYX/DKK1/FOSL1/THBS1/KRT17/CAVIN1/SERPINB8/GDF15 | 12 |
| GOBP_GLIAL_CELL_DIFFERENTIATION | GOBP_GLIAL_CELL_DIFFERENTIATION | GOBP_GLIAL_CELL_DIFFERENTIATION | 34/1438 | 218/23056 | 0.1559633 | 2.500619 | 5.741480 | 0.0000007 | 0.0000105 | 0.0000067 | TNFRSF1B/IL1B/DLX1/DLX2/EPHA4/SERPINE2/DNER/LAMB2/HES1/FGF5/LEF1/SH3TC2/ID4/TNFRSF21/GCM1/ADGRG6/IL6/GLI3/PTPRZ1/PTN/SHH/CLU/NOTCH1/MYRF/TRPC4/SOX8/NOG/SOX9/ITGB4/MAG/TGFB1/C5AR1/BMP2/LIF | 34 |
| GOBP_PARASYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_PARASYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_PARASYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT | 9/1438 | 19/23056 | 0.4736842 | 7.594759 | 7.416807 | 0.0000007 | 0.0000105 | 0.0000068 | NRP2/ACKR3/HES1/GDNF/TFAP2A/SEMA3A/NRP1/SIX1/HOXB2 | 9 |
| RASHI_NFKB1_TARGETS | RASHI_NFKB1_TARGETS | RASHI_NFKB1_TARGETS | 9/1438 | 19/23056 | 0.4736842 | 7.594759 | 7.416807 | 0.0000007 | 0.0000105 | 0.0000068 | CSF1/CXCL3/CXCL2/TNFAIP3/MAP3K8/NFKB2/BIRC3/NFKBIA/RELB | 9 |
| VERRECCHIA_RESPONSE_TO_TGFB1_C1 | VERRECCHIA_RESPONSE_TO_TGFB1_C1 | VERRECCHIA_RESPONSE_TO_TGFB1_C1 | 9/1438 | 19/23056 | 0.4736842 | 7.594759 | 7.416807 | 0.0000007 | 0.0000105 | 0.0000068 | HSPG2/NID1/SPARC/SERPINE1/ADAM9/PLAT/TCF7L2/CD44/ITGA3 | 9 |
| HP_JOINT_CONTRACTURE_OF_THE_HAND | HP_JOINT_CONTRACTURE_OF_THE_HAND | HP_JOINT_CONTRACTURE_OF_THE_HAND | 36/1438 | 238/23056 | 0.1512605 | 2.425217 | 5.700133 | 0.0000007 | 0.0000106 | 0.0000068 | MMP23B/ECE1/HSPG2/TBX15/LAMC2/PRG4/LAMB3/NLRP3/ACTG2/COL6A3/TWIST2/TGFBR2/WNT5A/FGFR3/DOK7/ADAMTS3/FAT4/PSMB8/COL12A1/GJA1/CCN2/GLI3/CAV1/SHH/TRPS1/TPM2/FGFR2/ITGA7/BMP4/FBN1/MMP2/NOG/ITGB4/PIEZO2/COL6A2/GPC4 | 36 |
| GOBP_TUBE_FORMATION | GOBP_TUBE_FORMATION | GOBP_TUBE_FORMATION | 27/1438 | 152/23056 | 0.1776316 | 2.848035 | 5.895633 | 0.0000008 | 0.0000109 | 0.0000070 | TGFB2/OSR1/WNT5A/EGF/IRX2/GDNF/CITED2/HOXA1/FZD1/PODXL/SHH/FZD6/CTHRC1/NOTCH1/MMRN2/FGFR2/ADM/BMP4/SIX1/SIX4/SOX8/NOG/SOX9/TGFB1/TGM2/SDC4/CELSR1 | 27 |
| GOBP_REGULATION_OF_PHAGOCYTOSIS | GOBP_REGULATION_OF_PHAGOCYTOSIS | GOBP_REGULATION_OF_PHAGOCYTOSIS | 21/1438 | 100/23056 | 0.2100000 | 3.367010 | 6.117954 | 0.0000008 | 0.0000109 | 0.0000070 | PTPRC/IL1B/IL15/ITGA2/F2RL1/DOCK2/CD36/COLEC10/IL15RA/MBL2/SFTPD/PTPRJ/APOA1/NCKAP1L/MFGE8/CNN2/C3/SIRPG/SIRPA/TGM2/IL2RB | 21 |
| GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_METANEPHROS_DEVELOPMENT | GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_METANEPHROS_DEVELOPMENT | GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_METANEPHROS_DEVELOPMENT | 10/1438 | 24/23056 | 0.4166667 | 6.680575 | 7.181023 | 0.0000008 | 0.0000109 | 0.0000070 | CD34/OSR1/LAMB2/WWTR1/GDNF/YAP1/BMP4/SALL1/LIF/PDGFB | 10 |
| GOBP_METANEPHRIC_EPITHELIUM_DEVELOPMENT | GOBP_METANEPHRIC_EPITHELIUM_DEVELOPMENT | GOBP_METANEPHRIC_EPITHELIUM_DEVELOPMENT | 10/1438 | 24/23056 | 0.4166667 | 6.680575 | 7.181023 | 0.0000008 | 0.0000109 | 0.0000070 | OSR1/LAMB2/WWTR1/HES1/WT1/YAP1/SOX8/SOX9/LIF/WNT7B | 10 |
| GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP | GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP | GRAHAM_CML_QUIESCENT_VS_CML_DIVIDING_UP | 10/1438 | 24/23056 | 0.4166667 | 6.680575 | 7.181023 | 0.0000008 | 0.0000109 | 0.0000070 | IL1B/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/CRHBP/SOD2/EMP1 | 10 |
| JEON_SMAD6_TARGETS_UP | JEON_SMAD6_TARGETS_UP | JEON_SMAD6_TARGETS_UP | 10/1438 | 24/23056 | 0.4166667 | 6.680575 | 7.181023 | 0.0000008 | 0.0000109 | 0.0000070 | CSF1/LAMC2/TGFB2/CXCL8/PSMB8/SERPINE1/FAS/SERPINH1/THBS1/FBN1 | 10 |
| GOBP_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION | 20/1438 | 92/23056 | 0.2173913 | 3.485517 | 6.160858 | 0.0000008 | 0.0000111 | 0.0000071 | RARB/WNT5A/HES1/NKX3-2/ENAM/IL31RA/BMP6/ROS1/FAM20C/SERPINE1/EXT1/NOTCH1/FGFR2/YAP1/BMP4/DLX3/GATA6/BMP2/CEBPB/GATA5 | 20 |
| DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_DN | DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_DN | DIAZ_CHRONIC_MYELOGENOUS_LEUKEMIA_DN | 23/1438 | 117/23056 | 0.1965812 | 3.151861 | 6.018304 | 0.0000008 | 0.0000113 | 0.0000073 | CD53/VAMP5/MYLK/BCL6/IL7R/CRHBP/TGFBI/CEBPD/KLF4/MYOF/PTPRE/MS4A4A/GLIPR1/FLT3/DACT1/ADAP2/CCR7/ELANE/GADD45B/KLF2/PRNP/MN1/IL13RA1 | 23 |
| KEGG_COMPLEMENT_AND_COAGULATION_CASCADES | KEGG_COMPLEMENT_AND_COAGULATION_CASCADES | KEGG_COMPLEMENT_AND_COAGULATION_CASCADES | 17/1438 | 69/23056 | 0.2463768 | 3.950253 | 6.329901 | 0.0000008 | 0.0000115 | 0.0000074 | CFH/TFPI/CFI/C9/SERPINE1/PLAT/MBL2/PLAU/VWF/C1S/C1R/C3AR1/SERPINA1/BDKRB1/C3/C5AR1/THBD | 17 |
| HP_TACHYCARDIA | HP_TACHYCARDIA | HP_TACHYCARDIA | 24/1438 | 126/23056 | 0.1904762 | 3.053977 | 5.962565 | 0.0000008 | 0.0000119 | 0.0000077 | ECE1/FMO3/KYNU/TECRL/MYOZ2/DSP/HFE/RHAG/TRDN/CITED2/SEMA3A/PYGM/SCNN1A/ACTC1/TPM1/HCN4/JUP/CAVIN1/KCNJ2/GATA6/DSG2/SCN1B/BMP2/JPH2 | 24 |
| GOBP_HETEROTYPIC_CELL_CELL_ADHESION | GOBP_HETEROTYPIC_CELL_CELL_ADHESION | GOBP_HETEROTYPIC_CELL_CELL_ADHESION | 16/1438 | 62/23056 | 0.2580645 | 4.137646 | 6.380384 | 0.0000009 | 0.0000122 | 0.0000079 | VCAM1/PTPRC/IL1B/ITGA4/DSP/PERP/KLF4/CD44/APOA1/ITGA5/ITGA7/GLDN/JUP/DSG2/MBP/SIRPA | 16 |
| WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | WP_HEMATOPOIETIC_STEM_CELL_DIFFERENTIATION | 16/1438 | 62/23056 | 0.2580645 | 4.137646 | 6.380384 | 0.0000009 | 0.0000122 | 0.0000079 | CSF1/CD34/IL1A/IL1B/THRB/LEF1/GYPA/CSF2/IL6/NOTCH1/NFE2/NCKAP1L/FOS/CSF3/NFATC2/RUNX1 | 16 |
| GOBP_REGULATION_OF_LIPID_TRANSPORT | GOBP_REGULATION_OF_LIPID_TRANSPORT | GOBP_REGULATION_OF_LIPID_TRANSPORT | 27/1438 | 153/23056 | 0.1764706 | 2.829420 | 5.855543 | 0.0000009 | 0.0000123 | 0.0000079 | LDLRAP1/PLA2G4A/AGT/IL1A/IL1B/PPARG/SPP1/EGF/DAB2/BMP6/EDN1/CAV1/SHH/ACSL5/APOC3/APOA1/NFKBIA/THBS1/CYP19A1/ANXA2/CES1/CETP/ABCA8/C1QTNF1/LIPG/TNFRSF11A/APOE | 27 |
| GOBP_GLIOGENESIS | GOBP_GLIOGENESIS | GOBP_GLIOGENESIS | 41/1438 | 291/23056 | 0.1408935 | 2.258999 | 5.574323 | 0.0000009 | 0.0000125 | 0.0000080 | TNFRSF1B/CSF1/TGFB2/IL1B/DLX1/DLX2/EPHA4/SERPINE2/DNER/LAMB2/HES1/FGF5/LEF1/SH3TC2/ID4/TNFRSF21/GCM1/ADGRG6/IL6/GLI3/PTPRZ1/PTN/SHH/CLU/PLAG1/ANXA1/NOTCH1/PITX3/MYRF/TRPC4/MMP14/CSPG4/SOX8/NOG/SOX9/ITGB4/MAG/TGFB1/C5AR1/BMP2/LIF | 41 |
| FRASOR_RESPONSE_TO_ESTRADIOL_DN | FRASOR_RESPONSE_TO_ESTRADIOL_DN | FRASOR_RESPONSE_TO_ESTRADIOL_DN | 18/1438 | 77/23056 | 0.2337662 | 3.748063 | 6.229608 | 0.0000009 | 0.0000125 | 0.0000081 | TGFB2/IL1R1/KYNU/LAMB2/TM4SF1/SLIT2/ANXA3/PLK2/IER3/STC1/CLU/MATN2/PPP1R3C/GPRC5A/KRT7/BMP4/SLC16A5/COL4A5 | 18 |
| GOCC_ACTOMYOSIN | GOCC_ACTOMYOSIN | GOCC_ACTOMYOSIN | 18/1438 | 77/23056 | 0.2337662 | 3.748063 | 6.229608 | 0.0000009 | 0.0000125 | 0.0000081 | FBLIM1/XIRP2/XIRP1/MYLK/LPP/ABLIM3/MICALL2/TRIP6/ZYX/PDLIM2/TEK/BAG3/LCP1/TPM1/CNN2/MYL9/GAS2L1/MYH9 | 18 |
| GOBP_CELL_JUNCTION_ASSEMBLY | GOBP_CELL_JUNCTION_ASSEMBLY | GOBP_CELL_JUNCTION_ASSEMBLY | 53/1438 | 421/23056 | 0.1258907 | 2.018454 | 5.439343 | 0.0000009 | 0.0000127 | 0.0000082 | AGRN/EPHA2/RHOC/S100A10/IGFN1/AGT/IL1B/ITGA6/FN1/DNER/WNT5A/EPHA3/PHLDB2/HEG1/CLDN1/CLDN16/IL1RAP/KDR/GRID2/CDH9/ITGA2/MDGA1/TPBG/GJA1/PTPRK/THBS2/MICALL2/FZD1/TRIP6/CAV1/ZNF703/TEK/NRP1/DKK1/VCL/PTPRJ/AMIGO2/ITGA5/MMP14/AJUBA/LRFN5/SIX1/SIX4/THBS1/CLDN6/CLDN7/JUP/PECAM1/ITGB4/SDC4/SRPX2/GPC4/SLITRK4 | 53 |
| HP_ABNORMAL_SYSTEMIC_BLOOD_PRESSURE | HP_ABNORMAL_SYSTEMIC_BLOOD_PRESSURE | HP_ABNORMAL_SYSTEMIC_BLOOD_PRESSURE | 57/1438 | 466/23056 | 0.1223176 | 1.961164 | 5.406134 | 0.0000009 | 0.0000128 | 0.0000082 | ECE1/LDLRAP1/PTPN22/ADAMTSL4/FMO3/CFH/TGFB2/AGT/ACTG2/KYNU/COL3A1/COL5A2/FN1/SP110/PPARG/TGFBR2/MYLK/CLDN1/CFI/RREB1/HFE/SIM1/GJA1/CCN2/TMEM270/CAV1/TNFRSF11B/GLIS3/TNFSF15/GSN/COL5A1/NOTCH1/ITGA8/NFKB2/FGFR2/SAA1/WT1/ALX4/APOA1/SCNN1A/KRT8/KRT18/FLT1/MMP14/SERPINA6/FBN1/SMAD6/MMP2/COL1A1/TNFRSF11A/C3/IL12RB1/THBD/PTGIS/GATA5/RUNX1/COL4A5 | 57 |
| GOBP_ENDOCRINE_PROCESS | GOBP_ENDOCRINE_PROCESS | GOBP_ENDOCRINE_PROCESS | 19/1438 | 85/23056 | 0.2235294 | 3.583932 | 6.155379 | 0.0000009 | 0.0000130 | 0.0000084 | ECE1/EDN2/AGT/IL1B/PPARG/FOXL2/SUCNR1/DAB2/FOXD1/F2RL1/CRHBP/BMP6/EDN1/GJA1/INHBA/PCSK5/FZD4/EDNRB/C1QTNF1 | 19 |
| HP_SUBCUTANEOUS_NODULE | HP_SUBCUTANEOUS_NODULE | HP_SUBCUTANEOUS_NODULE | 19/1438 | 85/23056 | 0.2235294 | 3.583932 | 6.155379 | 0.0000009 | 0.0000130 | 0.0000084 | ECM1/COL3A1/COL5A2/COL7A1/TNFRSF11B/TEK/COL5A1/FAS/FGFR2/HMGA2/MMP14/DACT1/FBN1/SALL1/MMP2/COL1A1/TNFRSF11A/APOE/PDGFB | 19 |
| SASSON_RESPONSE_TO_FORSKOLIN_DN | SASSON_RESPONSE_TO_FORSKOLIN_DN | SASSON_RESPONSE_TO_FORSKOLIN_DN | 19/1438 | 85/23056 | 0.2235294 | 3.583932 | 6.155379 | 0.0000009 | 0.0000130 | 0.0000084 | DHRS3/GBP1/ACTG2/RPRM/ITGB5/DAB2/CAP2/FLNC/TNFRSF11B/TPM2/VCL/PTPRE/CASP4/KRT18/PRKD1/THBS1/ITGA3/AXL/CARD10 | 19 |
| GOBP_POSITIVE_REGULATION_OF_BONE_MINERALIZATION | GOBP_POSITIVE_REGULATION_OF_BONE_MINERALIZATION | GOBP_POSITIVE_REGULATION_OF_BONE_MINERALIZATION | 13/1438 | 42/23056 | 0.3095238 | 4.962713 | 6.629418 | 0.0000009 | 0.0000134 | 0.0000086 | CCN1/OSR1/ADRB2/BMP6/TFAP2A/TENT5A/FAM20C/PTN/ALOX5/WNT10B/BMP4/TGFB1/BMP2 | 13 |
| GOBP_VENTRICULAR_SEPTUM_MORPHOGENESIS | GOBP_VENTRICULAR_SEPTUM_MORPHOGENESIS | GOBP_VENTRICULAR_SEPTUM_MORPHOGENESIS | 13/1438 | 42/23056 | 0.3095238 | 4.962713 | 6.629418 | 0.0000009 | 0.0000134 | 0.0000086 | TGFB2/TGFBR2/WNT5A/HES1/FGFRL1/SLIT2/CITED2/FZD1/ZFPM2/NOTCH1/FGFR2/BMP4/NOG | 13 |
| GOBP_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 32/1438 | 201/23056 | 0.1592040 | 2.552578 | 5.701840 | 0.0000010 | 0.0000135 | 0.0000086 | AGRN/EPHA2/S100A10/AGT/IL1B/WNT5A/EPHA3/PHLDB2/CLDN1/IL1RAP/KDR/GRID2/MDGA1/TPBG/THBS2/FZD1/CAV1/TEK/NRP1/DKK1/VCL/PTPRJ/AMIGO2/MMP14/LRFN5/SIX1/SIX4/THBS1/SDC4/SRPX2/GPC4/SLITRK4 | 32 |
| AGARWAL_AKT_PATHWAY_TARGETS | AGARWAL_AKT_PATHWAY_TARGETS | AGARWAL_AKT_PATHWAY_TARGETS | 7/1438 | 11/23056 | 0.6363636 | 10.203060 | 7.873983 | 0.0000010 | 0.0000135 | 0.0000087 | PTGS2/TGFA/SPP1/EGF/VEGFC/PLAU/MMP2 | 7 |
| GOBP_LATERAL_SPROUTING_FROM_AN_EPITHELIUM | GOBP_LATERAL_SPROUTING_FROM_AN_EPITHELIUM | GOBP_LATERAL_SPROUTING_FROM_AN_EPITHELIUM | 7/1438 | 11/23056 | 0.6363636 | 10.203060 | 7.873983 | 0.0000010 | 0.0000135 | 0.0000087 | WNT5A/SHH/SULF1/FGFR2/BMP4/NOG/CELSR1 | 7 |
| BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN | BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN | BERENJENO_TRANSFORMED_BY_RHOA_REVERSIBLY_DN | 11/1438 | 30/23056 | 0.3666667 | 5.878906 | 6.896489 | 0.0000010 | 0.0000136 | 0.0000088 | ERRFI1/CCN1/ACTG2/PHLDB2/CCN2/INHBA/SERPINE1/ADM/TAGLN/LATS2/THBS1 | 11 |
| DORSEY_GAB2_TARGETS | DORSEY_GAB2_TARGETS | DORSEY_GAB2_TARGETS | 11/1438 | 30/23056 | 0.3666667 | 5.878906 | 6.896489 | 0.0000010 | 0.0000136 | 0.0000088 | TNFRSF9/COL6A3/SPARC/SERPINE1/STC1/GSN/PHLDA2/CD44/CRYAB/THBS1/COL1A1 | 11 |
| MAHADEVAN_GIST_MORPHOLOGICAL_SWITCH | MAHADEVAN_GIST_MORPHOLOGICAL_SWITCH | MAHADEVAN_GIST_MORPHOLOGICAL_SWITCH | 8/1438 | 15/23056 | 0.5333333 | 8.551136 | 7.545039 | 0.0000010 | 0.0000137 | 0.0000088 | SPP1/MYO10/CCN2/TPM2/MMP3/MMP2/CDH13/ITGA3 | 8 |
| TSUNODA_CISPLATIN_RESISTANCE_UP | TSUNODA_CISPLATIN_RESISTANCE_UP | TSUNODA_CISPLATIN_RESISTANCE_UP | 8/1438 | 15/23056 | 0.5333333 | 8.551136 | 7.545039 | 0.0000010 | 0.0000137 | 0.0000088 | CCN1/EFEMP1/NT5E/CCN2/PLAU/C1S/ARHGDIB/DIO2 | 8 |
| MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | 49/1438 | 378/23056 | 0.1296296 | 2.078401 | 5.452279 | 0.0000010 | 0.0000137 | 0.0000088 | ARHGEF16/IL22RA1/SLC1A7/ADCY10/CAMK1G/TMEM63A/LBH/NRP2/MLPH/TMEM40/MITF/VGLL3/LRRC15/CXCL1/DSP/DDR1/ROS1/SASH1/EPHB4/EPHB6/MSC/NIPAL2/B4GALT1/TOR4A/ANXA8/MMRN2/SYT12/ALDH3B1/ROBO4/SLC6A13/SCNN1A/C3AR1/STYK1/HMGA2/NUAK1/OASL/MMP14/PYGL/LTBP2/NQO1/MRC2/MBP/CLEC4M/KLF2/CD22/NECTIN2/REM1/BIRC7/PDGFB | 49 |
| GOBP_IN_UTERO_EMBRYONIC_DEVELOPMENT | GOBP_IN_UTERO_EMBRYONIC_DEVELOPMENT | GOBP_IN_UTERO_EMBRYONIC_DEVELOPMENT | 50/1438 | 389/23056 | 0.1285347 | 2.060846 | 5.442322 | 0.0000010 | 0.0000138 | 0.0000088 | TIE1/CCN1/ELF3/COL3A1/CASP8/TGFBR2/HEG1/TM4SF1/HES1/SLC34A2/ADAMTS3/LEF1/CSF2/FOXC1/EDN1/MDFI/GCM1/GJA1/RSPO3/CITED2/GLI3/NECAB1/ZFPM2/ANGPT1/KLF4/NOTCH1/PLPP4/FGFR2/PHLDA2/ADM/FOSL1/YAP1/YBX3/IGF1/ZFP36L1/ESRRB/MYO1E/SOX8/FOXF1/KRT19/NOG/SOCS3/GATA6/KLF2/BMP2/CEBPB/LIF/MYH9/PDGFB/WNT7B | 50 |
| RIGGINS_TAMOXIFEN_RESISTANCE_DN | RIGGINS_TAMOXIFEN_RESISTANCE_DN | RIGGINS_TAMOXIFEN_RESISTANCE_DN | 34/1438 | 221/23056 | 0.1538462 | 2.466674 | 5.650455 | 0.0000010 | 0.0000139 | 0.0000089 | NMI/COL3A1/TM4SF1/RBM47/ANXA3/INPP4B/CTSO/DDX60/RAI14/DSP/CRYBG1/GJA1/SEMA3C/STC1/ADAM9/CEBPD/KLF4/MYOF/IFITM2/IFITM3/PLAAT4/RAB38/SCNN1A/EMP1/DNAJC15/IRF9/PYGL/ZFP36L1/SOX9/DSG2/SIGLEC15/PRNP/APOL6/CARD10 | 34 |
| HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | 21/1438 | 102/23056 | 0.2058824 | 3.300990 | 6.006754 | 0.0000011 | 0.0000149 | 0.0000096 | GBP1/TGFB2/CRIM1/SLCO2A1/SPARC/CRYBG1/PTPRK/TNS3/CAV1/TPM2/DKK1/HTRA1/ARHGDIB/EPS8/THBS1/NQO1/COTL1/CAVIN1/GAS2L1/COL4A6/PLS3 | 21 |
| WONG_ENDMETRIUM_CANCER_DN | WONG_ENDMETRIUM_CANCER_DN | WONG_ENDMETRIUM_CANCER_DN | 18/1438 | 78/23056 | 0.2307692 | 3.700011 | 6.160429 | 0.0000011 | 0.0000151 | 0.0000097 | LMOD1/NID1/EFEMP1/COL3A1/TWIST2/VGLL3/FOXL2/MME/FBXO32/PAPPA/WT1/IGFBP6/EDNRB/FBN1/ALDH1A2/CRISPLD2/EHD2/ADAMTS5 | 18 |
| YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | 18/1438 | 78/23056 | 0.2307692 | 3.700011 | 6.160429 | 0.0000011 | 0.0000151 | 0.0000097 | C1QTNF12/TFPI/COL3A1/COL6A3/NPNT/DAB2/SPARC/MEST/PYGM/ACTC1/FBN1/COL1A1/CNN1/COL18A1/COL6A2/KDELR3/NDP/BGN | 18 |
| GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 28/1438 | 164/23056 | 0.1707317 | 2.737406 | 5.758849 | 0.0000011 | 0.0000151 | 0.0000097 | TGFB2/IL1B/EPHA4/TGFBR2/WNT5A/EPHA3/PHLDB2/WWTR1/LEF1/DAB2/FOXC1/EDN1/IL6/LOXL2/ZNF703/HAS2/CRB2/NOTCH1/TCF7L2/FGFR2/BCL9L/HMGA2/BMP4/COL1A1/NOG/SOX9/TGFB1/BMP2 | 28 |
| WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER | WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER | WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER | 28/1438 | 164/23056 | 0.1707317 | 2.737406 | 5.758849 | 0.0000011 | 0.0000151 | 0.0000097 | TGFB2/WNT9A/NRP2/FN1/TWIST2/TGFBR2/WNT5A/CLDN1/CLDN16/SPARC/DSP/FZD1/FZD6/NOTCH1/FZD8/FZD4/WNT10B/ITGA5/LATS2/CLDN6/MMP2/CLDN7/JUP/GDF15/TGFB1/WNT7B/COL4A6/COL4A5 | 28 |
| GOBP_REGULATION_OF_HEART_CONTRACTION | GOBP_REGULATION_OF_HEART_CONTRACTION | GOBP_REGULATION_OF_HEART_CONTRACTION | 33/1438 | 212/23056 | 0.1556604 | 2.495762 | 5.642851 | 0.0000011 | 0.0000152 | 0.0000097 | HSPB7/ZC3H12A/EDN2/ATP2B4/TGFB2/AGT/BMP10/DES/KCNE4/THRB/HBEGF/DSP/EDN1/TBX18/GJA1/TRDN/CCN2/SEMA3A/CAV1/STC1/RNLS/ADM/KCNA5/SPX/EDNRB/TPM1/HCN4/JUP/MYL4/KCNJ2/DSG2/SCN1B/ADRA1D | 33 |
| SASSON_RESPONSE_TO_GONADOTROPHINS_DN | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | 19/1438 | 86/23056 | 0.2209302 | 3.542258 | 6.091758 | 0.0000011 | 0.0000155 | 0.0000099 | DHRS3/GBP1/ACTG2/RPRM/ITGB5/DAB2/CAP2/FLNC/TNFRSF11B/TPM2/VCL/PTPRE/CASP4/KRT18/PRKD1/THBS1/ITGA3/AXL/CARD10 | 19 |
| GOBP_REGULATION_OF_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION | GOBP_REGULATION_OF_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION | GOBP_REGULATION_OF_BIOLOGICAL_PROCESS_INVOLVED_IN_SYMBIOTIC_INTERACTION | 15/1438 | 56/23056 | 0.2678571 | 4.294655 | 6.366406 | 0.0000011 | 0.0000155 | 0.0000100 | CXCL8/CXCL6/TRIML2/TRIML1/F2RL1/TRIM38/FUCA2/CAV1/GSN/SFTPD/IFITM2/IFITM3/TRIM5/NECTIN2/LGALS1 | 15 |
| HP_SPLENOMEGALY | HP_SPLENOMEGALY | HP_SPLENOMEGALY | 47/1438 | 358/23056 | 0.1312849 | 2.104941 | 5.434268 | 0.0000011 | 0.0000157 | 0.0000101 | TNFRSF4/TNFRSF1B/FUCA1/HJV/KCNN3/FMO3/PTPRC/NLRP3/GYPC/CASP10/CASP8/PPARG/SLCO2A1/BCL6/CLDN1/ADAMTS3/FAT4/IL7R/RREB1/HFE/PSMB8/PSMB9/RHAG/STX11/IL6/SAMD9L/CAV1/GLIS3/NOTCH1/FAS/NFKB2/APOA1/TNFRSF1A/SLC7A7/EPB42/LAT/PSMB10/PIEZO1/CAVIN1/TNFRSF11A/TGFB1/KCNN4/APOE/BMP2/RUNX1/IL2RB/GPC4 | 47 |
| HP_ABNORMAL_ORAL_MUCOSA_MORPHOLOGY | HP_ABNORMAL_ORAL_MUCOSA_MORPHOLOGY | HP_ABNORMAL_ORAL_MUCOSA_MORPHOLOGY | 43/1438 | 315/23056 | 0.1365079 | 2.188684 | 5.478618 | 0.0000011 | 0.0000157 | 0.0000101 | GFI1/ECM1/KCNN3/LAMC2/PTPRC/LAMB3/NLRP3/KYNU/ITGA6/COL3A1/NABP1/CASP10/IL17RC/COL7A1/WNT5A/CD96/ADAMTS3/SPP1/FAT4/IL7R/ADAMTS2/DSP/TNFAIP3/PERP/FAM20C/IL6/TMEM270/SAMD9/FAS/FGFR2/SAA1/MMP1/C1S/C1R/KRT4/GLI1/MMP14/IRF9/MMP2/KRT17/ITGB4/ELANE/RIN2 | 43 |
| BROCKE_APOPTOSIS_REVERSED_BY_IL6 | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | 26/1438 | 146/23056 | 0.1780822 | 2.855259 | 5.799930 | 0.0000011 | 0.0000158 | 0.0000101 | SH2D2A/ATP2B4/LTBP1/NMI/BHLHE40/MYLK/HEG1/BCL6/SPP1/ELL2/HBEGF/PTP4A1/CAV2/MAP3K8/CD44/VWA5A/IRF9/MT1X/WIPI1/SOCS3/GADD45B/ICAM1/ZFP36/BCL3/CEBPB/MX1 | 26 |
| WIERENGA_STAT5A_TARGETS_DN | WIERENGA_STAT5A_TARGETS_DN | WIERENGA_STAT5A_TARGETS_DN | 31/1438 | 193/23056 | 0.1606218 | 2.575310 | 5.668031 | 0.0000012 | 0.0000159 | 0.0000102 | MTMR11/IFI16/ITPKB/RASGRP3/CAVIN2/CD96/MYLK/ITGB5/MGLL/SLC22A23/TREML1/OGFRL1/STX11/ZYX/ANGPT1/TPM2/NOTCH1/PROSER2/TSPAN32/MYEOV/UBASH3B/VWF/SPX/MSRB3/CCDC9B/RBPMS2/SMAD6/COTL1/PECAM1/TMC8/ZNF185 | 31 |
| HP_ABNORMAL_LEUKOCYTE_PHYSIOLOGY | HP_ABNORMAL_LEUKOCYTE_PHYSIOLOGY | HP_ABNORMAL_LEUKOCYTE_PHYSIOLOGY | 39/1438 | 274/23056 | 0.1423358 | 2.282123 | 5.506345 | 0.0000012 | 0.0000171 | 0.0000110 | TNFRSF1B/CASP10/CASP8/SP110/COL7A1/ADAMTS3/FAT4/IL7R/STING1/RREB1/HFE/PSMB8/PSMB9/PLA2G7/STX11/SAMD9L/TNFSF15/FAS/NFKB2/NCKAP1L/SLC7A7/SERPINA1/IL4R/IL21R/LAT/CAVIN1/COL1A1/TNFRSF11A/ELANE/CD70/PLVAP/IL12RB1/TGFB1/KCNN4/HMOX1/IL2RB/RAC2/MSN/GPC4 | 39 |
| TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP | 9/1438 | 20/23056 | 0.4500000 | 7.215021 | 7.171472 | 0.0000012 | 0.0000172 | 0.0000111 | CDA/MEST/ALOX5/PHLDA2/NRIP3/EPS8/SERPINB2/APOE/ZNF185 | 9 |
| ZIRN_TRETINOIN_RESPONSE_UP | ZIRN_TRETINOIN_RESPONSE_UP | ZIRN_TRETINOIN_RESPONSE_UP | 9/1438 | 20/23056 | 0.4500000 | 7.215021 | 7.171472 | 0.0000012 | 0.0000172 | 0.0000111 | DHRS3/RARB/VGLL3/SLCO2A1/PLK2/LAMA4/CCN2/PLAAT4/NID2 | 9 |
| FUJII_YBX1_TARGETS_UP | FUJII_YBX1_TARGETS_UP | FUJII_YBX1_TARGETS_UP | 13/1438 | 43/23056 | 0.3023256 | 4.847301 | 6.512654 | 0.0000013 | 0.0000176 | 0.0000113 | NR5A2/CAPG/EDIL3/PDK4/GIMAP2/SULF1/CLIC3/FAS/PLAAT4/NLRC5/CCL5/SLC16A3/MX2 | 13 |
| GOBP_LIPID_EXPORT_FROM_CELL | GOBP_LIPID_EXPORT_FROM_CELL | GOBP_LIPID_EXPORT_FROM_CELL | 13/1438 | 43/23056 | 0.3023256 | 4.847301 | 6.512654 | 0.0000013 | 0.0000176 | 0.0000113 | PLA2G4A/AGT/IL1A/IL1B/SPP1/DAB2/BMP6/EDN1/INHBA/FZD4/CYP19A1/C1QTNF1/TNFRSF11A | 13 |
| HP_ACANTHOSIS_NIGRICANS | HP_ACANTHOSIS_NIGRICANS | HP_ACANTHOSIS_NIGRICANS | 13/1438 | 43/23056 | 0.3023256 | 4.847301 | 6.512654 | 0.0000013 | 0.0000176 | 0.0000113 | HSD11B1/PPARG/CLDN1/FGFR3/PCSK1/PSMB8/PSMB9/CAV1/FGFR2/FOS/CYP19A1/JUP/CAVIN1 | 13 |
| LEIN_ASTROCYTE_MARKERS | LEIN_ASTROCYTE_MARKERS | LEIN_ASTROCYTE_MARKERS | 13/1438 | 43/23056 | 0.3023256 | 4.847301 | 6.512654 | 0.0000013 | 0.0000176 | 0.0000113 | S1PR1/MLPH/STAB1/ITGB5/SPARC/PLA2G7/GJA1/CLU/GSN/HEPACAM/MFGE8/SOX8/APOE | 13 |
| WP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS | WP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS | WP_MIRNA_TARGETS_IN_ECM_AND_MEMBRANE_RECEPTORS | 13/1438 | 43/23056 | 0.3023256 | 4.847301 | 6.512654 | 0.0000013 | 0.0000176 | 0.0000113 | ITGB6/COL3A1/COL5A2/FN1/COL6A3/LAMB2/ITGB5/LAMA4/THBS2/COL5A1/THBS1/ITGA11/COL6A2 | 13 |
| GOCC_APICAL_PART_OF_CELL | GOCC_APICAL_PART_OF_CELL | GOCC_APICAL_PART_OF_CELL | 53/1438 | 426/23056 | 0.1244131 | 1.994763 | 5.344862 | 0.0000013 | 0.0000176 | 0.0000113 | VCAM1/ADCY10/CD34/LCT/DPP4/FAP/CYBRD1/FN1/KCNE4/MUC13/PLD1/CLDN1/SLC34A2/ABCG2/SLC7A11/OSMR/ADRB2/HFE/ITPR3/CLIC5/ADGRF5/GJA1/SLC22A1/AQP1/CD36/SLC26A4/PODXL/ATP6V0A4/STC1/PLAT/FZD6/ANXA13/ADCY8/TEK/ANXA1/TRPM6/CRB2/NOTCH1/ITGA8/SLC22A18/SLC5A12/CD44/SLCO2B1/KCNA5/SCNN1A/SLC10A2/SLC24A4/CSPG4/SLC47A1/SLC16A3/SLC14A2/C5AR1/MSN | 53 |
| GOBP_ENDOTHELIUM_DEVELOPMENT | GOBP_ENDOTHELIUM_DEVELOPMENT | GOBP_ENDOTHELIUM_DEVELOPMENT | 25/1438 | 138/23056 | 0.1811594 | 2.904598 | 5.787736 | 0.0000013 | 0.0000179 | 0.0000115 | TIE1/S1PR1/CD34/IL1B/FSTL1/HEG1/CLDN1/KDR/ADAMTS12/F2RL1/BMP6/MET/STC1/S1PR3/NOTCH1/NRP1/VCL/ROBO4/TNFRSF1A/EDNRB/BMP4/PECAM1/ICAM1/COL18A1/MSN | 25 |
| LIM_MAMMARY_LUMINAL_MATURE_DN | LIM_MAMMARY_LUMINAL_MATURE_DN | LIM_MAMMARY_LUMINAL_MATURE_DN | 20/1438 | 95/23056 | 0.2105263 | 3.375448 | 5.983651 | 0.0000013 | 0.0000180 | 0.0000116 | TINAGL1/ITPKB/GYPC/FSTL1/P3H2/DAB2/MOXD1/FZD1/FBXO32/FAS/HTRA1/SERPINH1/CASP1/CRYAB/FOXO1/WTIP/APOE/TFAP2C/BACE2/COL6A2 | 20 |
| MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | 49/1438 | 382/23056 | 0.1282723 | 2.056638 | 5.370911 | 0.0000013 | 0.0000182 | 0.0000117 | ERRFI1/FBLIM1/CCN1/GBP2/OLFML3/S100A16/WNT9A/TMEM37/CYBRD1/COL5A2/AOX1/CASP8/ACKR3/COL6A3/BHLHE40/IRAK2/FSTL1/ITGB5/PLD1/COX7B2/PLAC8/CTSO/PPIC/TAPBP/PLA2G7/TENT5A/CCN2/PDGFA/SKAP2/HOXA1/LOXL2/CLU/TCIM/GSN/PLAC9/TRIM5/PLAAT3/VWA5A/KRT18/TMCC3/FOS/CRIP1/MFGE8/MSLN/WIPI1/RRAS/PRNP/TGM2/TBC1D8B | 49 |
| GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 16/1438 | 64/23056 | 0.2500000 | 4.008345 | 6.215606 | 0.0000014 | 0.0000185 | 0.0000119 | GFI1/CSF1/IKBKE/IL1R1/WNT5A/PARP14/TXK/TSLP/STING1/EDN1/TRIM56/DDX58/CASP4/CASP1/NLRC5/AXL | 16 |
| GOBP_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | GOBP_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | GOBP_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | 16/1438 | 64/23056 | 0.2500000 | 4.008345 | 6.215606 | 0.0000014 | 0.0000185 | 0.0000119 | ZC3H12A/PTGS2/ATP2B4/CD34/AGT/IL1B/EDN1/SOD2/CD36/CAV1/CLU/KLF4/KLRC4-KLRK1/KLF2/SIRPA/PTGIS | 16 |
| GOBP_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS | GOBP_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS | GOBP_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS | 22/1438 | 112/23056 | 0.1964286 | 3.149414 | 5.880967 | 0.0000014 | 0.0000187 | 0.0000120 | CASQ1/LMOD1/BMP10/PHLDB2/MYOZ2/SOX30/EDN1/LMOD2/FLNC/MYPN/MYOZ1/SYNPO2L/ANKRD1/SIX4/ACTC1/TPM1/MYLK3/KRT19/ITGB4/MAG/NECTIN2/MYL9 | 22 |
| BURTON_ADIPOGENESIS_1 | BURTON_ADIPOGENESIS_1 | BURTON_ADIPOGENESIS_1 | 11/1438 | 31/23056 | 0.3548387 | 5.689264 | 6.738139 | 0.0000014 | 0.0000192 | 0.0000124 | ERRFI1/DLX2/ELL2/IER3/CCN2/IL6/CEBPD/BAG3/PHLDA1/THBD/CEBPB | 11 |
| HP_JOINT_CONTRACTURES_INVOLVING_THE_JOINTS_OF_THE_FEET | HP_JOINT_CONTRACTURES_INVOLVING_THE_JOINTS_OF_THE_FEET | HP_JOINT_CONTRACTURES_INVOLVING_THE_JOINTS_OF_THE_FEET | 11/1438 | 31/23056 | 0.3548387 | 5.689264 | 6.738139 | 0.0000014 | 0.0000192 | 0.0000124 | HSPG2/COL7A1/FGFR3/DSP/PSMB8/GLI3/MMP1/FBN1/MMP2/JUP/PIEZO2 | 11 |
| OHGUCHI_LIVER_HNF4A_TARGETS_UP | OHGUCHI_LIVER_HNF4A_TARGETS_UP | OHGUCHI_LIVER_HNF4A_TARGETS_UP | 14/1438 | 50/23056 | 0.2800000 | 4.489346 | 6.370342 | 0.0000014 | 0.0000192 | 0.0000124 | FMO3/SULT1E1/DDR1/RCAN2/CYP39A1/CD36/PDK4/CA3/ANXA13/GSN/DRAM1/GADD45B/USP18/SMPX | 14 |
| GOBP_EPIBOLY | GOBP_EPIBOLY | GOBP_EPIBOLY | 12/1438 | 37/23056 | 0.3243243 | 5.200015 | 6.594209 | 0.0000014 | 0.0000193 | 0.0000124 | CCN1/RHOC/PHLDB2/ARHGAP24/HBEGF/RREB1/DDR1/COL5A1/CD44/ITGA5/LCP1/AJUBA | 12 |
| PID_FRA_PATHWAY | PID_FRA_PATHWAY | PID_FRA_PATHWAY | 12/1438 | 37/23056 | 0.3243243 | 5.200015 | 6.594209 | 0.0000014 | 0.0000193 | 0.0000124 | CXCL8/GJA1/IL6/PLAU/FOSL1/MMP1/MMP2/ITGB4/THBD/NFATC2/LIF/HMOX1 | 12 |
| GOBP_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | GOBP_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | GOBP_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | 29/1438 | 176/23056 | 0.1647727 | 2.641864 | 5.639228 | 0.0000015 | 0.0000201 | 0.0000129 | EPHA2/PTGS2/ATP2B4/PPARG/SLIT2/KDR/VEGFC/PLK2/FGF18/ADTRP/EPHB4/ANGPT1/ANXA1/KLF4/NOTCH1/JCAD/NRP1/MMRN2/APOA1/PRKD1/THBS1/JUP/TGFB1/APOE/HMOX1/MYH9/CARD10/PDGFB/SRPX2 | 29 |
| GOBP_NEURON_PROJECTION_GUIDANCE | GOBP_NEURON_PROJECTION_GUIDANCE | GOBP_NEURON_PROJECTION_GUIDANCE | 35/1438 | 235/23056 | 0.1489362 | 2.387950 | 5.515625 | 0.0000015 | 0.0000203 | 0.0000130 | EPHA2/ECE1/NEXN/LAMC2/LGR6/NRP2/EPHA4/LAMB2/SEMA3B/WNT5A/EPHA3/SLIT2/SEMA5A/GDNF/FOXD1/EDN1/LAMA2/HOXA2/GLI3/SEMA3C/SEMA3A/SEMA3D/EPHB4/EPHB6/SHH/EXT1/NOTCH1/NRP1/MYPN/ROBO4/LHX1/NOG/SEMA6B/SCN1B/RAC2 | 35 |
| GOCC_I_BAND | GOCC_I_BAND | GOCC_I_BAND | 25/1438 | 139/23056 | 0.1798561 | 2.883701 | 5.745063 | 0.0000015 | 0.0000203 | 0.0000131 | TRIM63/SYNC/NEXN/CASQ1/IGFN1/ATP2B4/BMP10/XIRP2/DES/MYOZ2/FLNC/PDLIM2/FBXO32/MYPN/MYOZ1/SYNPO2L/ANKRD1/BAG3/CRYAB/KCNA5/ACTC1/KRT19/JUP/MYL9/JPH2 | 25 |
| GOBP_TISSUE_REGENERATION | GOBP_TISSUE_REGENERATION | GOBP_TISSUE_REGENERATION | 17/1438 | 72/23056 | 0.2361111 | 3.785659 | 6.105703 | 0.0000015 | 0.0000205 | 0.0000132 | LGR6/TGFBR2/TXK/TEC/GJA1/PTN/EPPK1/SPAAR/ANXA1/NOTCH1/MYOZ1/YAP1/WNT10B/IGF1/SGCA/KLK6/RUNX1 | 17 |
| BASAKI_YBX1_TARGETS_DN | BASAKI_YBX1_TARGETS_DN | BASAKI_YBX1_TARGETS_DN | 50/1438 | 395/23056 | 0.1265823 | 2.029542 | 5.323009 | 0.0000015 | 0.0000208 | 0.0000134 | DHRS3/GBP5/FRRS1/IFI16/SULT1C2/TMEM37/DPP4/GALNT3/TFPI/BHLHE40/ARL14/HES1/RBM47/SPP1/SLC7A11/SERPINB1/HLA-E/SLC25A27/PTP4A1/NT5E/CRYBG1/ARHGAP18/SCIN/MET/STC1/IDO1/ASPH/PTGS1/PAPSS2/HTRA1/SLC22A18/ADM/SYTL2/MMP1/MPZL2/CPM/TPCN1/PRKD1/FOS/SERPINA1/CGNL1/ALDH1A2/CA12/ACSM3/SALL1/GRB7/TNFRSF11A/GDF15/THBD/SAT1 | 50 |
| HP_AUTOIMMUNITY | HP_AUTOIMMUNITY | HP_AUTOIMMUNITY | 30/1438 | 186/23056 | 0.1612903 | 2.586029 | 5.601299 | 0.0000016 | 0.0000210 | 0.0000135 | GFI1/PTPN22/FCGR2A/CASP10/SPP1/IL7R/STING1/RREB1/ITPR3/RHAG/CCN2/TNFAIP3/IL6/CAV1/TNFSF15/FAS/NFKB2/C1S/C1R/FLT1/SLC7A7/LAT/MMP2/ELANE/SEMA6B/C3/IL12RB1/IL2RB/COL4A6/COL4A5 | 30 |
| GOBP_HEART_GROWTH | GOBP_HEART_GROWTH | GOBP_HEART_GROWTH | 20/1438 | 96/23056 | 0.2083333 | 3.340287 | 5.926157 | 0.0000016 | 0.0000211 | 0.0000136 | S1PR1/TGFB2/AGT/BMP10/TGFBR2/HEG1/FOXC1/EDN1/CITED2/FGF20/ZFPM2/NOTCH1/FGFR2/WT1/YAP1/GLI1/IGF1/NOG/GATA6/RUNX1 | 20 |
| GOMF_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | GOMF_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | GOMF_SERINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY | 20/1438 | 96/23056 | 0.2083333 | 3.340287 | 5.926157 | 0.0000016 | 0.0000211 | 0.0000136 | AGT/CRIM1/TFPI/SERPINE2/COL6A3/COL7A1/ITIH3/SERPINB1/CD109/SERPINE1/SERPINH1/SERPINE3/SERPINA10/SERPINA6/SERPINA1/ANXA2/SERPINB7/SERPINB2/SERPINB8/WFDC10B | 20 |
| SERVITJA_LIVER_HNF1A_TARGETS_DN | SERVITJA_LIVER_HNF1A_TARGETS_DN | SERVITJA_LIVER_HNF1A_TARGETS_DN | 28/1438 | 167/23056 | 0.1676647 | 2.688231 | 5.647172 | 0.0000016 | 0.0000211 | 0.0000136 | GBP2/PLA2G4A/CFH/RASSF5/HSD11B1/IL1R1/DPP4/RTP3/ALDH1L1/SLCO2A1/IL1RAP/CFI/PDGFC/C9/LECT2/HLA-E/CADPS2/PPP1R3C/CYP26A1/LOXL4/C1R/IGF1/LCP1/SERPINA1/PNPLA3/CELSR1/DACH2/IL13RA1 | 28 |
| YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_9 | 18/1438 | 80/23056 | 0.2250000 | 3.607510 | 6.025431 | 0.0000016 | 0.0000215 | 0.0000138 | CD53/S100A13/PLA2G4A/ELF3/CAVIN2/HES1/HLA-E/PSMB8/PSMB9/AHR/UPK3B/MDFIC/CASP1/EMP1/IRF9/ANPEP/KRT19/A4GALT | 18 |
| HP_APLASIA_HYPOPLASIA_OF_THE_SKIN | HP_APLASIA_HYPOPLASIA_OF_THE_SKIN | HP_APLASIA_HYPOPLASIA_OF_THE_SKIN | 29/1438 | 177/23056 | 0.1638418 | 2.626938 | 5.603938 | 0.0000017 | 0.0000224 | 0.0000144 | LAMC2/LAMB3/TGFB2/ITGA6/COL3A1/COL5A2/COL6A3/TWIST2/PPARG/TGFBR2/COL7A1/FGFRL1/ADAMTS2/DSP/TFAP2A/COL12A1/GSN/COL5A1/NOTCH1/ALX4/MMP1/C1S/C1R/PRKD1/FBN1/COL1A1/ITGB4/TNFRSF11A/COL6A2 | 29 |
| DELPUECH_FOXO3_TARGETS_UP | DELPUECH_FOXO3_TARGETS_UP | DELPUECH_FOXO3_TARGETS_UP | 16/1438 | 65/23056 | 0.2461538 | 3.946678 | 6.135708 | 0.0000017 | 0.0000227 | 0.0000146 | PDZK1IP1/CCN1/TGFA/BCL6/EDN1/TNFRSF21/SEMA3C/CAV1/CLU/GSN/PHLDA2/EMP1/IGFBP6/GRB7/SERPINB8/SAT1 | 16 |
| GOBP_ANIMAL_ORGAN_REGENERATION | GOBP_ANIMAL_ORGAN_REGENERATION | GOBP_ANIMAL_ORGAN_REGENERATION | 16/1438 | 65/23056 | 0.2461538 | 3.946678 | 6.135708 | 0.0000017 | 0.0000227 | 0.0000146 | TGFBR2/CLDN1/ANXA3/IL6/GLI3/PTPN3/NOTCH1/ADM/NNMT/GLI1/FLT3/LCP1/SERPINA10/AXL/CEBPB/HMOX1 | 16 |
| KORKOLA_YOLK_SAC_TUMOR | KORKOLA_YOLK_SAC_TUMOR | KORKOLA_YOLK_SAC_TUMOR | 16/1438 | 65/23056 | 0.2461538 | 3.946678 | 6.135708 | 0.0000017 | 0.0000227 | 0.0000146 | NMI/P3H2/PCDH10/CEBPD/HAS2/SRGN/CYP26A1/CCKBR/APOA1/C1S/C1R/HMGA2/LUM/SALL1/BMP2/COL4A6 | 16 |
| GERY_CEBP_TARGETS | GERY_CEBP_TARGETS | GERY_CEBP_TARGETS | 24/1438 | 131/23056 | 0.1832061 | 2.937413 | 5.735317 | 0.0000017 | 0.0000230 | 0.0000148 | CRABP2/IFI16/PPARG/CXCL6/CXCL2/EREG/HBEGF/MAFK/CLU/PLAT/KLF4/APBB1IP/BAG3/POSTN/FOS/RRAD/CD68/SERPINB2/GADD45B/C3/PRNP/PROCR/HMOX1/SAT1 | 24 |
| GOBP_AMINOGLYCAN_METABOLIC_PROCESS | GOBP_AMINOGLYCAN_METABOLIC_PROCESS | GOBP_AMINOGLYCAN_METABOLIC_PROCESS | 24/1438 | 131/23056 | 0.1832061 | 2.937413 | 5.735317 | 0.0000017 | 0.0000230 | 0.0000148 | FUCA1/IL1B/GALNT5/ITIH3/EGF/IL15/CHSY3/FOXC1/UST/CSGALNACT1/ANGPT1/EXT1/HAS2/ST3GAL1/CEMIP2/CD44/EDNRB/HS3ST3A1/B3GNT3/TGFB1/HAS1/PDGFB/CHST7/BGN | 24 |
| GOBP_RESPONSE_TO_OXYGEN_LEVELS | GOBP_RESPONSE_TO_OXYGEN_LEVELS | GOBP_RESPONSE_TO_OXYGEN_LEVELS | 43/1438 | 320/23056 | 0.1343750 | 2.154485 | 5.363653 | 0.0000017 | 0.0000230 | 0.0000148 | VCAM1/PTGS2/CD34/TGFB2/IL1A/DPP4/EPHA4/PPARG/TGFBR2/SOD3/VEGFC/ITGA2/EDN1/CCN2/CITED2/SOD2/PDGFA/AQP1/CAV1/LOXL2/STC1/PLAT/AQP3/NOTCH1/PLAU/FAS/ADM/CARD16/CRYAB/KCNA5/FOXO1/MMP14/AJUBA/ZFP36L1/THBS1/MMP2/MYOCD/COL1A1/GATA6/WTIP/BMP2/PTGIS/HMOX1 | 43 |
| REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS | 44/1438 | 331/23056 | 0.1329305 | 2.131325 | 5.346922 | 0.0000018 | 0.0000235 | 0.0000151 | ECE1/HTR1D/EDN2/S1PR1/AGT/GPR39/ACKR3/HRH1/ACKR2/CCR3/SUCNR1/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/F2RL1/ADRB2/EDN1/HCRTR2/GPR37/PNOC/ANXA1/S1PR3/NPY4R/HTR7/CCKBR/SAA1/P2RY2/C3AR1/HCAR1/EDNRB/BDKRB1/GPR132/CCL5/CCR7/C3/S1PR5/C5AR1/FPR1/ADRA1D/CYSLTR1/LPAR4 | 44 |
| GOBP_REGULATION_OF_HORMONE_LEVELS | GOBP_REGULATION_OF_HORMONE_LEVELS | GOBP_REGULATION_OF_HORMONE_LEVELS | 59/1438 | 499/23056 | 0.1182365 | 1.895730 | 5.217243 | 0.0000018 | 0.0000235 | 0.0000151 | C1QTNF12/DHRS3/ECE1/RPE65/GFI1/CRABP2/ILDR2/AGT/SRD5A2/CYP26B1/IL1B/DPP4/PPARG/FOXL2/UGT2B7/SULT1E1/SPP1/DAB2/FOXD1/CRHBP/PCSK1/BMP6/EDN1/HFE/PLA2G7/DDO/GJA1/IL6/INHBA/AKR1B10/AKR1B15/SHH/ADCY8/ANXA1/PCSK5/AKR1C3/ALOX5/PAPSS2/CYP26A1/TCF7L2/ADM/FZD4/KCNA5/EDNRB/DIO2/CYP46A1/CYP19A1/ALDH1A2/ALDH1A3/SOX8/CCL5/GIP/C1QTNF1/IL4I1/KLK6/IL11/BMP2/BACE2/LIF | 59 |
| GOBP_NEGATIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY | 15/1438 | 58/23056 | 0.2586207 | 4.146564 | 6.188135 | 0.0000018 | 0.0000241 | 0.0000155 | HJV/CRIM1/DLX1/PPARG/WNT5A/BMPER/FZD1/NOTCH1/DKK1/HTRA1/FBN1/RBPMS2/SMAD6/NOG/FSTL3 | 15 |
| LIM_MAMMARY_LUMINAL_PROGENITOR_UP | LIM_MAMMARY_LUMINAL_PROGENITOR_UP | LIM_MAMMARY_LUMINAL_PROGENITOR_UP | 15/1438 | 58/23056 | 0.2586207 | 4.146564 | 6.188135 | 0.0000018 | 0.0000241 | 0.0000155 | PDZK1IP1/GALNT15/CLDN1/SLC34A2/IL15/C10orf90/BBOX1/TNFAIP2/HAPLN3/ANPEP/ALDH1A3/C1QTNF1/C3/IL4I1/CYP24A1 | 15 |
| GOBP_GLOMERULAR_EPITHELIUM_DEVELOPMENT | GOBP_GLOMERULAR_EPITHELIUM_DEVELOPMENT | GOBP_GLOMERULAR_EPITHELIUM_DEVELOPMENT | 10/1438 | 26/23056 | 0.3846154 | 6.166684 | 6.798387 | 0.0000018 | 0.0000241 | 0.0000155 | CD34/LAMB2/FOXC1/PODXL/EXT1/WT1/EDNRB/BMP4/MYO1E/PECAM1 | 10 |
| GOBP_OUTFLOW_TRACT_SEPTUM_MORPHOGENESIS | GOBP_OUTFLOW_TRACT_SEPTUM_MORPHOGENESIS | GOBP_OUTFLOW_TRACT_SEPTUM_MORPHOGENESIS | 10/1438 | 26/23056 | 0.3846154 | 6.166684 | 6.798387 | 0.0000018 | 0.0000241 | 0.0000155 | TGFB2/NRP2/TGFBR2/SEMA3C/ZFPM2/NRP1/FGFR2/BMP4/SMAD6/GATA6 | 10 |
| REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION | REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION | REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION | 10/1438 | 26/23056 | 0.3846154 | 6.166684 | 6.798387 | 0.0000018 | 0.0000241 | 0.0000155 | NLRP3/IL1A/IL1B/NT5E/GSDMD/NFKB2/CASP1/C3AR1/C3/HMOX1 | 10 |
| WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_UP | WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_UP | WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_UP | 10/1438 | 26/23056 | 0.3846154 | 6.166684 | 6.798387 | 0.0000018 | 0.0000241 | 0.0000155 | LAMC2/CXCL3/PSMB8/PDGFA/TNFRSF10C/CREB3L1/SERPINH1/KRT8/CRIP1/GDF15 | 10 |
| GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 32/1438 | 207/23056 | 0.1545894 | 2.478590 | 5.511294 | 0.0000018 | 0.0000243 | 0.0000156 | EDN2/CD53/S100A13/IL1R1/SERPINE2/PPARG/TM4SF1/CXCL6/CXCL2/BTC/HLA-E/GJA1/KLF4/ANXA8L1/SLC22A18/WT1/CD82/FOSL1/CASP4/ARHGDIB/EPS8/HMGA2/NFKBIA/ZFP36L1/FOS/BNC1/KRT15/KRT19/ITGB4/FXYD5/SDC4/GATA5 | 32 |
| GOBP_RESPONSE_TO_COLD | GOBP_RESPONSE_TO_COLD | GOBP_RESPONSE_TO_COLD | 14/1438 | 51/23056 | 0.2745098 | 4.401320 | 6.271562 | 0.0000018 | 0.0000243 | 0.0000156 | CASP8/TRPM8/PLAC8/ADRB2/GMPR/SLC25A27/SOD2/TRPA1/ADM/FOXO1/NFKBIA/FOS/DIO2/METRNL | 14 |
| GOBP_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | GOBP_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | GOBP_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 30/1438 | 188/23056 | 0.1595745 | 2.558518 | 5.533895 | 0.0000020 | 0.0000258 | 0.0000166 | RHOC/ECM1/S100A13/IKBKE/IL1A/IL1B/CASP10/CASP8/SHISA5/TLR3/TRIML2/TRIML1/PLK2/F2RL1/TRIM38/GJA1/CD36/NEK6/TRIM5/BIRC3/CASP1/CARD16/TNFRSF1A/TNFRSF19/AJUBA/PRKD1/CCR7/HMOX1/APOL3/LGALS1 | 30 |
| REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2 | 24/1438 | 132/23056 | 0.1818182 | 2.915160 | 5.691164 | 0.0000020 | 0.0000261 | 0.0000168 | ECM1/TGFB2/FN1/ITIH3/EGF/VEGFC/SPARC/CD109/PDGFA/CD36/SERPINE1/RARRES2/CLU/TOR4A/SRGN/VCL/APOA1/VWF/IGF1/SERPINA1/THBS1/PECAM1/TGFB1/PDGFB | 24 |
| GOBP_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | GOBP_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | GOBP_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | 28/1438 | 169/23056 | 0.1656805 | 2.656418 | 5.574079 | 0.0000020 | 0.0000263 | 0.0000169 | TNFRSF4/TNFRSF1B/PTPN22/PTPRC/TGFB2/NLRP3/IL1R1/IL1B/WNT5A/CD96/BCL6/SPON2/TLR3/F2RL1/MZB1/HFE/HLA-E/IL6/CD36/ANGPT1/DDX58/APOA1/STAT6/IL4R/IL27RA/CD22/TGFB1/HMOX1 | 28 |
| GOCC_BASOLATERAL_PLASMA_MEMBRANE | GOCC_BASOLATERAL_PLASMA_MEMBRANE | GOCC_BASOLATERAL_PLASMA_MEMBRANE | 34/1438 | 228/23056 | 0.1491228 | 2.390943 | 5.443735 | 0.0000020 | 0.0000269 | 0.0000173 | ATP2B4/TGFA/CLDN1/SLC4A4/NKD2/DSP/SLC22A1/AQP1/SLC26A7/ADCY8/EPPK1/TEK/B4GALT1/AQP7/AQP3/ANXA1/SLC16A12/CD44/SLC6A13/TRPC4/SLC7A7/ANXA2/CLDN7/SLC47A1/ITGA3/ABCC3/ABCA8/SLC16A3/SLC14A1/ALPK2/C5AR1/PDGFB/MLC1/MSN | 34 |
| HATADA_METHYLATED_IN_LUNG_CANCER_UP | HATADA_METHYLATED_IN_LUNG_CANCER_UP | HATADA_METHYLATED_IN_LUNG_CANCER_UP | 48/1438 | 377/23056 | 0.1273210 | 2.041385 | 5.258046 | 0.0000021 | 0.0000276 | 0.0000178 | FBLIM1/CSF1/ADAMTSL4/CNIH3/ITPKB/VAMP5/AOX1/IQCA1/GALNT15/RARB/DOK7/STK32B/SLIT2/GRID2/ACOT12/TGFBI/GFPT2/TFAP2A/ID4/FUCA2/HOXA7/TRIP6/RARRES2/TNFRSF10C/NECAB1/RSPO2/COL5A1/ZCCHC24/MMRN2/TLL2/TAGLN/SLC46A3/LRFN5/NID2/HCN4/BNC1/CDH13/SLC47A1/LHX1/CAVIN1/COPZ2/COL1A1/C1QTNF1/CNN1/HSPB6/JPH2/APCDD1L/SLITRK4 | 48 |
| GOBP_AXON_DEVELOPMENT | GOBP_AXON_DEVELOPMENT | GOBP_AXON_DEVELOPMENT | 57/1438 | 479/23056 | 0.1189979 | 1.907939 | 5.178994 | 0.0000022 | 0.0000283 | 0.0000182 | EPHA2/ECE1/EDN2/NEXN/CRABP2/LAMC2/LGR6/ITGA4/NRP2/FN1/EPHA4/LAMB2/SEMA3B/WNT5A/EPHA3/SLIT2/SPP1/SEMA5A/GDNF/ACTBL2/FOXD1/EDN1/DDR1/TNFRSF21/LAMA2/UST/HOXA2/GLI3/SEMA3C/SEMA3A/SEMA3D/EPHB4/PTPRZ1/PTN/EPHB6/SHH/EXT1/KLF4/NOTCH1/NRP1/MYPN/VCL/FGFR2/ROBO4/FOXB1/MMP2/TRPV2/LHX1/NOG/MBP/SEMA6B/SCN1B/MAG/APOE/NCAM2/RAC2/SLITRK4 | 57 |
| NABA_ECM_AFFILIATED | NABA_ECM_AFFILIATED | NABA_ECM_AFFILIATED | 28/1438 | 170/23056 | 0.1647059 | 2.640792 | 5.537928 | 0.0000023 | 0.0000296 | 0.0000190 | SEMA3B/MUC13/ANXA3/SEMA5A/SEMA3C/SEMA3A/SEMA3D/COLEC10/ANXA13/ANXA1/ANXA8L1/ANXA8/MBL2/SFTPD/FREM2/ANXA2/CSPG4/C1QTNF8/C1QTNF1/COLEC12/SEMA6B/CLEC4M/MUC16/SDC4/ELFN2/LGALS2/LGALS1/GPC4 | 28 |
| GOBP_FEMALE_SEX_DIFFERENTIATION | GOBP_FEMALE_SEX_DIFFERENTIATION | GOBP_FEMALE_SEX_DIFFERENTIATION | 23/1438 | 124/23056 | 0.1854839 | 2.973933 | 5.684295 | 0.0000023 | 0.0000296 | 0.0000190 | SRD5A2/WNT5A/FOXL2/SLIT2/KDR/EREG/FST/FOXC1/INHBA/ZFPM2/DMRTA1/WT1/FZD4/PGR/MMP14/CYP19A1/NUPR1/MMP2/LHX1/AXL/CEBPB/COL9A3/DACH2 | 23 |
| HALMOS_CEBPA_TARGETS_DN | HALMOS_CEBPA_TARGETS_DN | HALMOS_CEBPA_TARGETS_DN | 13/1438 | 45/23056 | 0.2888889 | 4.631865 | 6.289592 | 0.0000023 | 0.0000298 | 0.0000191 | CCN1/MTMR11/ELF3/HES1/F2RL1/CCN2/RBPMS/PLAU/SCNN1A/SMAD6/GRB7/TFAP2C/GAS2L1 | 13 |
| KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS | KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS | KUROZUMI_RESPONSE_TO_ONCOCYTIC_VIRUS | 13/1438 | 45/23056 | 0.2888889 | 4.631865 | 6.289592 | 0.0000023 | 0.0000298 | 0.0000191 | TNFRSF1B/IL1A/IL1B/CXCL2/SPP1/IL15/CASP1/CCL5/CCR7/C3/IL11/IL2RB/IL13RA1 | 13 |
| GOBP_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | 17/1438 | 74/23056 | 0.2297297 | 3.683344 | 5.962832 | 0.0000023 | 0.0000298 | 0.0000191 | VCAM1/ATP2B4/NRP2/KDR/ADAMTS3/VEGFC/ADAMTS12/FOXC1/TSPAN12/ANXA1/GAS1/NOTCH1/JCAD/NRP1/FLT3/FLT1/PRKD1 | 17 |
| WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS | WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS | WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS | 17/1438 | 74/23056 | 0.2297297 | 3.683344 | 5.962832 | 0.0000023 | 0.0000298 | 0.0000191 | AGRN/LAMB2/MME/CLDN1/UTRN/PODXL/NOTCH1/DKK1/VCL/WT1/KRT8/MYO1E/ITGA3/ITGB4/TGFB1/MYH9/COL4A5 | 17 |
| AMIT_EGF_RESPONSE_240_HELA | AMIT_EGF_RESPONSE_240_HELA | AMIT_EGF_RESPONSE_240_HELA | 15/1438 | 59/23056 | 0.2542373 | 4.076283 | 6.101982 | 0.0000023 | 0.0000299 | 0.0000192 | TM4SF1/SLC7A11/IL7R/PLK2/ELL2/GRAMD2B/GFPT2/DKK1/DNMBP/EHBP1L1/TNFRSF1A/THBS1/BCL3/IL11/SDC4 | 15 |
| CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP | 15/1438 | 59/23056 | 0.2542373 | 4.076283 | 6.101982 | 0.0000023 | 0.0000299 | 0.0000192 | CAPG/VAMP5/ITGA6/WWTR1/SPP1/SEMA5A/GDNF/TGFBI/GJA1/PDGFA/HMGA2/SERPINA1/NUPR1/FXYD5/KCNN4 | 15 |
| GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET | GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET | GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET | 15/1438 | 59/23056 | 0.2542373 | 4.076283 | 6.101982 | 0.0000023 | 0.0000299 | 0.0000192 | CCN1/RHOC/WNT5A/PHLDB2/ARHGAP24/HBEGF/RREB1/DDR1/COL5A1/NOTCH1/CD44/ITGA5/LCP1/AJUBA/HOXB2 | 15 |
| GOBP_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | 37/1438 | 260/23056 | 0.1423077 | 2.281673 | 5.360298 | 0.0000023 | 0.0000301 | 0.0000193 | ECM1/IFI16/PTGS2/AGT/CRIM1/TFPI/SERPINE2/COL6A3/COL7A1/ITIH3/SERPINB1/CD109/AQP1/SERPINE1/KLF4/CRB2/ANXA8L1/ANXA8/CD44/SERPINH1/BIRC3/CARD16/CRYAB/SERPINE3/SERPINA10/SERPINA6/SERPINA1/THBS1/ANXA2/SERPINB7/SERPINB2/SERPINB8/TNFSF14/C3/PRNP/WFDC10B/BIRC7 | 37 |
| BHAT_ESR1_TARGETS_VIA_AKT1_DN | BHAT_ESR1_TARGETS_VIA_AKT1_DN | BHAT_ESR1_TARGETS_VIA_AKT1_DN | 18/1438 | 82/23056 | 0.2195122 | 3.519522 | 5.894692 | 0.0000023 | 0.0000304 | 0.0000195 | EDN2/PTPN14/TGFB2/IL1R1/GALNT10/SLC22A23/RNF144B/SASH1/PDK4/LRATD2/S1PR3/NRP1/EHF/SYTL2/EPS8/NPAS3/CDYL2/SLC16A5 | 18 |
| GOBP_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS | GOBP_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS | GOBP_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS | 18/1438 | 82/23056 | 0.2195122 | 3.519522 | 5.894692 | 0.0000023 | 0.0000304 | 0.0000195 | ZC3H12A/PTGS2/ATP2B4/CD34/AGT/IL1B/CPS1/EDN1/SOD2/CD36/CAV1/CLU/KLF4/KLRC4-KLRK1/NQO1/KLF2/SIRPA/PTGIS | 18 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT | 29/1438 | 180/23056 | 0.1611111 | 2.583156 | 5.499511 | 0.0000024 | 0.0000307 | 0.0000197 | GBP1/IL1A/IL1B/DLX1/DLX2/SEMA3B/WNT5A/HES1/SPP1/SEMA5A/ID4/IL6/SEMA3C/SEMA3A/SEMA3D/PTN/S1PR3/PAEP/NOTCH1/NRP1/PITX3/IGF1/EDNRB/NFATC4/FBN1/NOG/MBP/SEMA6B/MAG | 29 |
| CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | 14/1438 | 52/23056 | 0.2692308 | 4.316679 | 6.175295 | 0.0000024 | 0.0000308 | 0.0000198 | ADAMTS12/EDIL3/GFPT2/RBM24/UTRN/SEMA3A/FLNC/LOXL2/ZCCHC24/NUAK1/ALPK2/KLF2/IL11/COL6A2 | 14 |
| HALLMARK_KRAS_SIGNALING_DN | HALLMARK_KRAS_SIGNALING_DN | HALLMARK_KRAS_SIGNALING_DN | 31/1438 | 200/23056 | 0.1550000 | 2.485174 | 5.440595 | 0.0000025 | 0.0000324 | 0.0000208 | HTR1D/EDN2/IFI44L/TGFB2/THRB/ITIH3/CLDN16/FGFR3/GRID2/EGF/GDNF/EDN1/CYP39A1/UPK3B/CPA2/AKR1B10/PLAG1/NPY4R/PTPRJ/KRT4/SERPINA10/ACTC1/KRT13/KRT15/COPZ2/GPRC5C/SERPINB2/LYPD3/CKM/MX1/SMPX | 31 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 32/1438 | 210/23056 | 0.1523810 | 2.443182 | 5.418509 | 0.0000025 | 0.0000326 | 0.0000210 | PTPRC/ATP2B4/TGFA/IL1B/EPHA4/WNT5A/EPGN/EGF/PDGFC/ADRB2/FGF18/EDN1/TPD52L1/SASH1/PDGFA/ARHGEF5/ADAM9/TCIM/FZD8/DKK1/FZD4/HMGA2/FLT3/FLT1/AJUBA/THBS1/TNFRSF11A/ELANE/TGFB1/BMP2/PDGFB/TENM1 | 32 |
| MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 25/1438 | 143/23056 | 0.1748252 | 2.803038 | 5.578100 | 0.0000026 | 0.0000333 | 0.0000214 | EPHA2/RASSF5/CCDC85A/GALNT3/FGF5/GPAT3/CDS1/CCNO/PLAG1/GDF6/RSPO2/COL27A1/P2RY2/ELMOD1/ADAMTS8/KCNH3/FLT1/RAB20/ESRRB/SLC24A4/BMF/FOXB1/SMAD6/HCN4/GPRC5C | 25 |
| WP_COMPLEMENT_SYSTEM | WP_COMPLEMENT_SYSTEM | WP_COMPLEMENT_SYSTEM | 20/1438 | 99/23056 | 0.2020202 | 3.239067 | 5.758128 | 0.0000026 | 0.0000336 | 0.0000216 | CFH/SPP1/CFI/C9/ITGA2/MBL2/ADM/APOA1/C1S/C1R/C3AR1/SELPLG/THBS1/ELANE/C3/CLEC4M/ICAM1/C5AR1/FPR1/PRNP | 20 |
| GOCC_PLATELET_ALPHA_GRANULE_LUMEN | GOCC_PLATELET_ALPHA_GRANULE_LUMEN | GOCC_PLATELET_ALPHA_GRANULE_LUMEN | 16/1438 | 67/23056 | 0.2388060 | 3.828867 | 5.980591 | 0.0000026 | 0.0000337 | 0.0000216 | TGFB2/FN1/EGF/VEGFC/SPARC/PDGFA/SERPINE1/CLU/TOR4A/SRGN/VWF/IGF1/SERPINA1/THBS1/TGFB1/PDGFB | 16 |
| HP_HYPEREXTENSIBLE_SKIN | HP_HYPEREXTENSIBLE_SKIN | HP_HYPEREXTENSIBLE_SKIN | 16/1438 | 67/23056 | 0.2388060 | 3.828867 | 5.980591 | 0.0000026 | 0.0000337 | 0.0000216 | TGFB2/COL3A1/COL5A2/TWIST2/FGFR3/ADAMTS2/COL12A1/COL5A1/FGFR2/C1S/C1R/SLC7A7/FBLN5/FBN1/COL1A1/RIN2 | 16 |
| SWEET_LUNG_CANCER_KRAS_UP | SWEET_LUNG_CANCER_KRAS_UP | SWEET_LUNG_CANCER_KRAS_UP | 57/1438 | 482/23056 | 0.1182573 | 1.896064 | 5.127579 | 0.0000026 | 0.0000338 | 0.0000217 | ERRFI1/FUCA1/CTSS/LAMC2/LAMB3/GALNT3/ITGA4/NABP1/SERPINE2/BHLHE40/PPARG/SLC34A2/SLC4A4/CXCL2/SPP1/ELL2/CSF2/TGFBI/ADAM19/MDFI/PLA2G7/ROS1/GJA1/CITED2/SERPINE1/MDFIC/MSR1/CLU/PTGR1/PTGS1/ITGA8/HHEX/ACSL5/PHLDA2/CD44/KRT7/KRT8/KRT18/PHLDA1/LCP1/BMP4/THBS1/BCL2A1/IL4R/MT1X/COTL1/CLDN7/CD68/HAP1/TNFSF9/AXL/IL11/SIRPA/PRNP/MX1/COL18A1/SAT1 | 57 |
| GOBP_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | 29/1438 | 181/23056 | 0.1602210 | 2.568884 | 5.465172 | 0.0000027 | 0.0000341 | 0.0000219 | RUNX3/ZC3H12A/PTPRC/ITPKB/NLRP3/CYP26B1/TGFBR2/BCL6/LEF1/IL15/IL7R/VNN1/INHBA/GLI3/SHH/ANXA1/IL15RA/NCKAP1L/TESPA1/MMP14/BMP4/ZFP36L1/IL4R/TNFSF9/IL12RB1/AXL/PSG9/IL4I1/RUNX1 | 29 |
| HP_ANTINUCLEAR_ANTIBODY_POSITIVITY | HP_ANTINUCLEAR_ANTIBODY_POSITIVITY | HP_ANTINUCLEAR_ANTIBODY_POSITIVITY | 12/1438 | 39/23056 | 0.3076923 | 4.933348 | 6.340515 | 0.0000027 | 0.0000343 | 0.0000220 | PTPN22/FCGR2A/CASP10/SPP1/STING1/TNFAIP3/TNFSF15/FAS/SLC7A7/MMP2/IL12RB1/IL2RB | 12 |
| HP_ECTOPIA_LENTIS | HP_ECTOPIA_LENTIS | HP_ECTOPIA_LENTIS | 12/1438 | 39/23056 | 0.3076923 | 4.933348 | 6.340515 | 0.0000027 | 0.0000343 | 0.0000220 | HSPG2/ADAMTSL4/P3H2/TAPBP/ASPH/COL5A1/WT1/LTBP2/FBN1/LOXL1/COL18A1/NDP | 12 |
| GOBP_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | GOBP_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | GOBP_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | 10/1438 | 27/23056 | 0.3703704 | 5.938289 | 6.621785 | 0.0000027 | 0.0000350 | 0.0000225 | PTGS2/IL1B/OSMR/HLA-E/IL6/ALOX5AP/CCR7/TNFRSF11A/CREB3L3/C3 | 10 |
| MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_UP | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_UP | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_UP | 10/1438 | 27/23056 | 0.3703704 | 5.938289 | 6.621785 | 0.0000027 | 0.0000350 | 0.0000225 | SOD3/CXCL2/PLAC8/F2RL1/HBEGF/PLA2G7/ANKRD1/HMGA2/SLC14A1/SERPINB2 | 10 |
| WESTON_VEGFA_TARGETS_12HR | WESTON_VEGFA_TARGETS_12HR | WESTON_VEGFA_TARGETS_12HR | 10/1438 | 27/23056 | 0.3703704 | 5.938289 | 6.621785 | 0.0000027 | 0.0000350 | 0.0000225 | COL6A3/SULT1E1/MEST/AQP7/ANKRD1/NNMT/MMP2/SDC4/SAT1/BGN | 10 |
| WP_APOPTOSIS_MODULATION_AND_SIGNALING | WP_APOPTOSIS_MODULATION_AND_SIGNALING | WP_APOPTOSIS_MODULATION_AND_SIGNALING | 19/1438 | 91/23056 | 0.2087912 | 3.347629 | 5.787235 | 0.0000027 | 0.0000351 | 0.0000226 | TNFRSF1B/IL1R1/CASP10/CASP8/TNFRSF10C/TNFRSF10A/AIFM2/FAS/BAG3/BIRC3/CASP4/CASP1/TNFRSF1A/PRKD1/NFKBIA/FOS/BMF/BCL2A1/BIRC7 | 19 |
| HP_ABDOMINAL_PAIN | HP_ABDOMINAL_PAIN | HP_ABDOMINAL_PAIN | 42/1438 | 315/23056 | 0.1333333 | 2.137784 | 5.244023 | 0.0000028 | 0.0000355 | 0.0000228 | ECE1/GFI1/PTPN22/CFH/NLRP3/ACTG2/GYPC/NABP1/TGFBR2/MITF/CLDN16/ARHGAP24/SPP1/CFI/GDNF/HFE/IL6/TMEM270/SEMA3C/SEMA3D/MET/PTPN3/CRB2/FAS/SAA1/WT1/BIRC3/TNFRSF1A/FLT1/EDNRB/EPB42/MYO1E/PIEZO1/ELANE/SCN1B/KCNN4/BMP2/RUNX1/APOL1/TBC1D8B/COL4A6/COL4A5 | 42 |
| GOBP_DIENCEPHALON_DEVELOPMENT | GOBP_DIENCEPHALON_DEVELOPMENT | GOBP_DIENCEPHALON_DEVELOPMENT | 17/1438 | 75/23056 | 0.2266667 | 3.634233 | 5.893246 | 0.0000028 | 0.0000355 | 0.0000228 | SRD5A2/NRP2/WNT5A/HES1/SEMA5A/PCSK1/SEMA3A/SHH/NRP1/GLI1/BMP4/ALDH1A2/FOXB1/SALL1/HAP1/NOG/BMP2 | 17 |
| GOBP_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS | 26/1438 | 153/23056 | 0.1699346 | 2.724627 | 5.520124 | 0.0000028 | 0.0000361 | 0.0000232 | LDLRAP1/CCN1/PTGS2/AGT/IL1A/IL1B/PPARG/AADAC/FGFR3/DAB2/BMP6/ADGRF5/TEK/ANXA1/ADM/RAB38/APOA1/FLT3/FLT1/PRKD1/TNFAIP8L3/CES1/CCR7/TGFB1/APOE/PDGFB | 26 |
| SCHRAETS_MLL_TARGETS_UP | SCHRAETS_MLL_TARGETS_UP | SCHRAETS_MLL_TARGETS_UP | 11/1438 | 33/23056 | 0.3333333 | 5.344460 | 6.441189 | 0.0000029 | 0.0000367 | 0.0000236 | IFI16/CD34/CAVIN2/SERPINE2/TPD52L1/HOXA1/FZD6/FAS/MMP10/FOS/GPC4 | 11 |
| WP_PROSTAGLANDIN_SIGNALING | WP_PROSTAGLANDIN_SIGNALING | WP_PROSTAGLANDIN_SIGNALING | 11/1438 | 33/23056 | 0.3333333 | 5.344460 | 6.441189 | 0.0000029 | 0.0000367 | 0.0000236 | CSF1/NLRP3/IL1A/IL1B/CXCL8/CXCL1/AHR/IL6/CASP1/KLRD1/TGFB1 | 11 |
| GOBP_NEURAL_CREST_CELL_MIGRATION | GOBP_NEURAL_CREST_CELL_MIGRATION | GOBP_NEURAL_CREST_CELL_MIGRATION | 15/1438 | 60/23056 | 0.2500000 | 4.008345 | 6.017711 | 0.0000029 | 0.0000367 | 0.0000236 | NRP2/FN1/SEMA3B/SEMA5A/GDNF/EDN1/SEMA3C/SEMA3A/SEMA3D/SHH/NRP1/EDNRB/BMP4/SOX8/SEMA6B | 15 |
| JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_DN | 15/1438 | 60/23056 | 0.2500000 | 4.008345 | 6.017711 | 0.0000029 | 0.0000367 | 0.0000236 | HSPG2/CSF1/COL6A3/FSTL1/TXK/SULT1E1/IL6/AQP1/STAT6/PYGL/MYL4/ALPK2/ELANE/EMP3/IL11 | 15 |
| LEE_LIVER_CANCER_DENA_UP | LEE_LIVER_CANCER_DENA_UP | LEE_LIVER_CANCER_DENA_UP | 15/1438 | 60/23056 | 0.2500000 | 4.008345 | 6.017711 | 0.0000029 | 0.0000367 | 0.0000236 | VCAM1/CTSS/SPP1/PLAT/FABP4/ANXA1/ANKRD1/PTPRE/THBS1/ANXA2/BCL2A1/MFGE8/SOX9/KDELR3/COL4A5 | 15 |
| GOBP_VIRAL_PROCESS | GOBP_VIRAL_PROCESS | GOBP_VIRAL_PROCESS | 51/1438 | 415/23056 | 0.1228916 | 1.970367 | 5.144777 | 0.0000029 | 0.0000368 | 0.0000237 | TNFRSF4/EPHA2/ZC3H12A/GFI1/IFI16/RNASEL/NR5A2/ITGB6/ITGB5/CLDN1/LRRC15/CXCL8/LEF1/GYPA/TRIML2/TRIML1/ITGA2/TRIM38/MOG/MDFIC/CAV2/CAV1/ST3GAL1/PARP10/PCSK5/GSN/NOTCH1/NRP1/MBL2/IFITM2/IFITM3/TRIM5/ITGA5/HMGA2/SELPLG/TPCN1/OASL/ANPEP/CLDN6/CCL5/CLEC4M/ICAM1/ZFP36/AXL/NECTIN2/APOE/MX1/LGALS1/APOBEC3A/APOBEC3G/APOBEC3H | 51 |
| GOBP_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 25/1438 | 144/23056 | 0.1736111 | 2.783573 | 5.537259 | 0.0000029 | 0.0000372 | 0.0000239 | RNF220/LGR6/WNT5A/LEF1/EGF/SEMA5A/DAB2/RSPO3/TNFAIP3/CAV1/SHH/SULF1/RSPO2/CCN4/DKK1/HHEX/FGFR2/YAP1/WNT10B/DACT1/SALL1/JUP/COL1A1/TGFB1/BMP2 | 25 |
| GOBP_INTERFERON_GAMMA_PRODUCTION | GOBP_INTERFERON_GAMMA_PRODUCTION | GOBP_INTERFERON_GAMMA_PRODUCTION | 22/1438 | 117/23056 | 0.1880342 | 3.014823 | 5.635039 | 0.0000029 | 0.0000373 | 0.0000240 | ZC3H12A/PTPN22/IL1R1/IL1B/WNT5A/CD96/TXK/TLR3/F2RL1/INHBA/CD274/PDCD1LG2/NLRP6/KLRC4-KLRK1/CCR7/EBI3/IL27RA/IL12RB1/AXL/BCL3/SIRPA/PRNP | 22 |
| WP_VEGFAVEGFR2_SIGNALING_PATHWAY | WP_VEGFAVEGFR2_SIGNALING_PATHWAY | WP_VEGFAVEGFR2_SIGNALING_PATHWAY | 53/1438 | 438/23056 | 0.1210046 | 1.940112 | 5.123230 | 0.0000030 | 0.0000375 | 0.0000241 | EPHA2/NEXN/CCN1/S1PR1/RHOC/SH2D2A/PTGS2/PLA2G4A/PTPN14/BMP10/NRP2/FN1/ACKR3/ITGB5/KDR/CXCL8/TRPC3/INPP4B/HBEGF/ADRB2/RCAN2/GJA1/CCN2/SOD2/CAV1/PTPRZ1/TNFRSF10C/ADAM9/ANXA1/DKK1/PLAU/VCL/MMRN2/FAS/HTRA1/HBD/MICAL2/PTPRJ/MMP10/SLC2A14/RND1/STAT6/FLT1/FOXO1/MMP14/PRKD1/NFKBIA/CGNL1/MMP2/ICAM1/BMP2/NFATC2/MYH9 | 53 |
| JISON_SICKLE_CELL_DISEASE_UP | JISON_SICKLE_CELL_DISEASE_UP | JISON_SICKLE_CELL_DISEASE_UP | 29/1438 | 182/23056 | 0.1593407 | 2.554769 | 5.431063 | 0.0000030 | 0.0000375 | 0.0000241 | GBP1/GBP2/VAMP5/KYNU/FN1/MITF/ITGB5/ANXA3/IL15/ABLIM3/MICB/PSMB8/PSMB9/TRIP6/ADM/NFE2/OASL/ANXA2/TPM1/IFI35/ELANE/GADD45B/BLVRB/AXL/EMP3/MYL9/MX1/GAS2L1/HMOX1 | 29 |
| KYNG_DNA_DAMAGE_DN | KYNG_DNA_DAMAGE_DN | KYNG_DNA_DAMAGE_DN | 29/1438 | 182/23056 | 0.1593407 | 2.554769 | 5.431063 | 0.0000030 | 0.0000375 | 0.0000241 | GBP1/CD53/PRELP/COL3A1/NRP2/FN1/SERPINE2/SEMA3B/ITGB5/CXCL2/CRHBP/CCN2/ITGB8/CD36/PDGFRL/ANXA1/TCF7L2/SAA1/PRSS23/CRYAB/NNMT/IGF1/TPM1/MT1X/KRT13/SERPINB2/CNN1/RIN2/CEBPB | 29 |
| GOBP_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 24/1438 | 135/23056 | 0.1777778 | 2.850379 | 5.561154 | 0.0000030 | 0.0000377 | 0.0000242 | HJV/LTBP1/CRIM1/DLX1/PPARG/WNT5A/VEPH1/FST/CD109/BMPER/FZD1/CAV2/CAV1/HTRA4/NOTCH1/DKK1/HTRA1/BCL9L/FBN1/RBPMS2/SMAD6/NOG/FSTL3/BMP2 | 24 |
| SERVITJA_LIVER_HNF1A_TARGETS_UP | SERVITJA_LIVER_HNF1A_TARGETS_UP | SERVITJA_LIVER_HNF1A_TARGETS_UP | 24/1438 | 135/23056 | 0.1777778 | 2.850379 | 5.561154 | 0.0000030 | 0.0000377 | 0.0000242 | FMO3/PPARG/FGFRL1/SULT1E1/CXCL2/NPNT/SERPINB1/ARHGAP18/PDK4/SERPINE1/AKR1B10/FABP4/LY6K/TNFRSF19/THBS1/ANXA2/TNFRSF12A/NQO1/ABCC3/GADD45B/CDC42EP5/SDCBP2/ADAMTS5/LGALS1 | 24 |
| GOBP_EXTRACELLULAR_MATRIX_ASSEMBLY | GOBP_EXTRACELLULAR_MATRIX_ASSEMBLY | GOBP_EXTRACELLULAR_MATRIX_ASSEMBLY | 13/1438 | 46/23056 | 0.2826087 | 4.531173 | 6.182922 | 0.0000030 | 0.0000377 | 0.0000242 | TIE1/LAMB3/AGT/COL3A1/LAMB2/PHLDB2/HAS2/NOTCH1/EFEMP2/FBLN5/SOX9/TGFB1/HAS1 | 13 |
| MARCHINI_TRABECTEDIN_RESISTANCE_DN | MARCHINI_TRABECTEDIN_RESISTANCE_DN | MARCHINI_TRABECTEDIN_RESISTANCE_DN | 13/1438 | 46/23056 | 0.2826087 | 4.531173 | 6.182922 | 0.0000030 | 0.0000377 | 0.0000242 | NID1/COL3A1/BHLHE40/FSTL1/CITED2/ANKRD1/ADM/LOXL1/CDH13/SLC16A3/BCAM/SIRPA/PRNP | 13 |
| EPPERT_HSC_R | EPPERT_HSC_R | EPPERT_HSC_R | 23/1438 | 126/23056 | 0.1825397 | 2.926728 | 5.593169 | 0.0000030 | 0.0000377 | 0.0000242 | CFH/CRIM1/TFPI/PLSCR4/LPP/HES1/SEL1L3/INPP4B/NPR3/CRHBP/RUNX2/CD109/TMEM200A/ADGRG6/MAFK/RBPMS/KLF4/COL5A1/DRAM1/FLT3/FOXO1/HOXB2/HOXB3 | 23 |
| HUPER_BREAST_BASAL_VS_LUMINAL_UP | HUPER_BREAST_BASAL_VS_LUMINAL_UP | HUPER_BREAST_BASAL_VS_LUMINAL_UP | 14/1438 | 53/23056 | 0.2641509 | 4.235232 | 6.081426 | 0.0000030 | 0.0000382 | 0.0000245 | S100A2/IL1A/IL1B/ITGA6/SERPINE2/P3H2/GJA1/PTPRZ1/AQP3/HTRA1/MMP10/AMIGO2/POSTN/CA12 | 14 |
| GOBP_T_CELL_DIFFERENTIATION | GOBP_T_CELL_DIFFERENTIATION | GOBP_T_CELL_DIFFERENTIATION | 37/1438 | 263/23056 | 0.1406844 | 2.255647 | 5.282005 | 0.0000030 | 0.0000382 | 0.0000245 | RUNX3/ZC3H12A/PTPN22/MR1/PTPRC/ITPKB/NLRP3/CYP26B1/IL1A/IL1B/TGFBR2/BCL6/LEF1/IL15/IL7R/DOCK2/RUNX2/VNN1/IL6/GLI3/SHH/ANXA1/FZD8/NCKAP1L/TESPA1/STAT6/BMP4/ZFP36L1/IL4R/CCR7/TNFSF9/IL12RB1/PSG9/BCL3/RELB/IL4I1/RUNX1 | 37 |
| GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_HOST | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_HOST | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_HOST | 30/1438 | 192/23056 | 0.1562500 | 2.505216 | 5.401663 | 0.0000031 | 0.0000382 | 0.0000246 | TNFRSF4/EPHA2/ITGB6/ITGB5/CLDN1/CXCL8/GYPA/TRIML2/TRIML1/ITGA2/TRIM38/MOG/FUCA2/CAV2/CAV1/GSN/NRP1/IFITM2/IFITM3/TRIM5/ITGA5/SELPLG/TPCN1/ANPEP/CLDN6/CLEC4M/ICAM1/AXL/NECTIN2/LGALS1 | 30 |
| GOCC_VESICLE_LUMEN | GOCC_VESICLE_LUMEN | GOCC_VESICLE_LUMEN | 43/1438 | 327/23056 | 0.1314985 | 2.108365 | 5.206199 | 0.0000031 | 0.0000383 | 0.0000246 | CDA/FUCA1/ECM1/S100A11/TGFB2/FN1/ITIH3/CXCL1/PLAC8/EGF/VEGFC/PCSK1/SPARC/DOCK2/SERPINB1/FUCA2/PDGFA/SERPINE1/RARRES2/CLU/GSDMD/GSN/TOR4A/ALOX5/SRGN/VCL/APOA1/VWF/IGF1/PYGL/SERPINA1/THBS1/ANXA2/COTL1/CRISPLD2/JUP/GIP/ELANE/CNN2/C3/GMFG/TGFB1/PDGFB | 43 |
| GOBP_REGULATION_OF_GLIOGENESIS | GOBP_REGULATION_OF_GLIOGENESIS | GOBP_REGULATION_OF_GLIOGENESIS | 20/1438 | 100/23056 | 0.2000000 | 3.206676 | 5.703543 | 0.0000031 | 0.0000383 | 0.0000246 | TNFRSF1B/IL1B/DLX1/DLX2/SERPINE2/HES1/ID4/IL6/PTPRZ1/PTN/SHH/PLAG1/NOTCH1/PITX3/SOX8/NOG/MAG/TGFB1/BMP2/LIF | 20 |
| GOBP_EYE_MORPHOGENESIS | GOBP_EYE_MORPHOGENESIS | GOBP_EYE_MORPHOGENESIS | 26/1438 | 154/23056 | 0.1688312 | 2.706934 | 5.481440 | 0.0000032 | 0.0000401 | 0.0000258 | EPHA2/RPE65/IGFN1/WNT9A/EFEMP1/COL5A2/THRB/RARB/WNT5A/COL8A1/FOXL2/KDR/TFAP2A/CITED2/GLI3/TSPAN12/CRB2/COL5A1/PITX3/CABP4/BMP4/FBN1/ALDH1A3/SOX8/LHX1/SOX9 | 26 |
| AMIT_EGF_RESPONSE_120_HELA | AMIT_EGF_RESPONSE_120_HELA | AMIT_EGF_RESPONSE_120_HELA | 16/1438 | 68/23056 | 0.2352941 | 3.772560 | 5.905260 | 0.0000032 | 0.0000401 | 0.0000258 | EPHA2/RUNX3/TGFA/AMOTL2/CXCL8/CXCL1/CXCL2/HBEGF/EPHB4/TCIM/FOSL1/TAGLN/JUP/IL27RA/GDF15/SAT1 | 16 |
| GOBP_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | GOBP_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | GOBP_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | 16/1438 | 68/23056 | 0.2352941 | 3.772560 | 5.905260 | 0.0000032 | 0.0000401 | 0.0000258 | TNFRSF18/TNFSF18/PARP14/HES1/FGFR3/IL15/IL31RA/TSLP/CSF2/IL6/TNFRSF1A/IGF1/FLT3/CTF1/CCL5/LIF | 16 |
| GOBP_RESPONSE_TO_ESTROGEN | GOBP_RESPONSE_TO_ESTROGEN | GOBP_RESPONSE_TO_ESTROGEN | 16/1438 | 68/23056 | 0.2352941 | 3.772560 | 5.905260 | 0.0000032 | 0.0000401 | 0.0000258 | TGFBR2/SLC34A2/ZNF366/CRHBP/CITED2/GLI3/CAV1/TNFRSF11B/MMP14/SMAD6/HAPLN3/IL4R/MMP2/KRT19/GATA6/HMOX1 | 16 |
| HP_INCREASED_BLOOD_PRESSURE | HP_INCREASED_BLOOD_PRESSURE | HP_INCREASED_BLOOD_PRESSURE | 49/1438 | 394/23056 | 0.1243655 | 1.993999 | 5.132621 | 0.0000032 | 0.0000403 | 0.0000259 | ECE1/LDLRAP1/PTPN22/ADAMTSL4/FMO3/CFH/TGFB2/AGT/ACTG2/COL3A1/FN1/SP110/PPARG/TGFBR2/MYLK/CLDN1/CFI/RREB1/HFE/GJA1/CCN2/TMEM270/CAV1/TNFRSF11B/GLIS3/TNFSF15/NOTCH1/ITGA8/FGFR2/WT1/ALX4/APOA1/SCNN1A/KRT8/KRT18/FLT1/MMP14/SERPINA6/FBN1/SMAD6/MMP2/TNFRSF11A/C3/IL12RB1/THBD/PTGIS/GATA5/RUNX1/COL4A5 | 49 |
| BIOCARTA_LAIR_PATHWAY | BIOCARTA_LAIR_PATHWAY | BIOCARTA_LAIR_PATHWAY | 8/1438 | 17/23056 | 0.4705882 | 7.545120 | 6.962489 | 0.0000033 | 0.0000407 | 0.0000262 | VCAM1/IL1A/ITGA4/CXCL8/IL6/SELPLG/C3/ICAM1 | 8 |
| GOBP_CELL_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_CELL_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_CELL_CELL_ADHESION_MEDIATED_BY_INTEGRIN | 8/1438 | 17/23056 | 0.4705882 | 7.545120 | 6.962489 | 0.0000033 | 0.0000407 | 0.0000262 | DPP4/ITGA4/NPNT/PODXL/ADAM9/ITGA5/PIEZO1/CCL5 | 8 |
| LE_SKI_TARGETS_UP | LE_SKI_TARGETS_UP | LE_SKI_TARGETS_UP | 8/1438 | 17/23056 | 0.4705882 | 7.545120 | 6.962489 | 0.0000033 | 0.0000407 | 0.0000262 | SERPINE2/ADAMTS6/AKR1C3/NRP1/CD44/HMGA2/KRT19/ITGB4 | 8 |
| LEI_HOXC8_TARGETS_DN | LEI_HOXC8_TARGETS_DN | LEI_HOXC8_TARGETS_DN | 8/1438 | 17/23056 | 0.4705882 | 7.545120 | 6.962489 | 0.0000033 | 0.0000407 | 0.0000262 | SPP1/ADAM19/GAS1/ANKRD1/TAGLN/NQO1/KRT19/CNN1 | 8 |
| WP_CELLS_AND_MOLECULES_INVOLVED_IN_LOCAL_ACUTE_INFLAMMATORY_RESPONSE | WP_CELLS_AND_MOLECULES_INVOLVED_IN_LOCAL_ACUTE_INFLAMMATORY_RESPONSE | WP_CELLS_AND_MOLECULES_INVOLVED_IN_LOCAL_ACUTE_INFLAMMATORY_RESPONSE | 8/1438 | 17/23056 | 0.4705882 | 7.545120 | 6.962489 | 0.0000033 | 0.0000407 | 0.0000262 | VCAM1/IL1A/ITGA4/CXCL8/IL6/SELPLG/C3/ICAM1 | 8 |
| FERRARI_RESPONSE_TO_FENRETINIDE_UP | FERRARI_RESPONSE_TO_FENRETINIDE_UP | FERRARI_RESPONSE_TO_FENRETINIDE_UP | 9/1438 | 22/23056 | 0.4090909 | 6.559110 | 6.728003 | 0.0000033 | 0.0000408 | 0.0000262 | DHRS3/PTGS2/BHLHE40/CXCL3/CXCL2/SEMA3C/ST3GAL1/GPRC5A/BMP2 | 9 |
| GOBP_LABYRINTHINE_LAYER_MORPHOGENESIS | GOBP_LABYRINTHINE_LAYER_MORPHOGENESIS | GOBP_LABYRINTHINE_LAYER_MORPHOGENESIS | 9/1438 | 22/23056 | 0.4090909 | 6.559110 | 6.728003 | 0.0000033 | 0.0000408 | 0.0000262 | CCN1/LEF1/GCM1/RSPO3/FGFR2/ADM/ZFP36L1/SOCS3/WNT7B | 9 |
| HP_OSTEOPOROSIS | HP_OSTEOPOROSIS | HP_OSTEOPOROSIS | 39/1438 | 285/23056 | 0.1368421 | 2.194041 | 5.231245 | 0.0000033 | 0.0000409 | 0.0000263 | HSPG2/HJV/ADCY10/LAMC2/LAMB3/TGFBR2/COL7A1/SLCO2A1/SGMS2/FAT4/SPARC/ADAMTS2/HFE/RUNX2/TENT5A/SIM1/TMEM270/ZFPM2/TNFRSF11B/TNFSF15/DKK1/WT1/MMP1/IGF1/SLC7A7/MMP14/PYGL/CYP19A1/BNC1/MMP2/CAVIN1/COL1A1/SOX9/TNFRSF11A/IL12RB1/BMP2/RIN2/RUNX1/PLS3 | 39 |
| WP_NRF2_PATHWAY | WP_NRF2_PATHWAY | WP_NRF2_PATHWAY | 25/1438 | 145/23056 | 0.1724138 | 2.764376 | 5.496767 | 0.0000033 | 0.0000412 | 0.0000265 | EPHA2/TGFB2/TGFA/TGFBR2/EPHA3/SOD3/UGT2B7/SLC7A11/HBEGF/SLC6A7/PTGR1/SLC5A12/SLC6A13/SLC2A14/SERPINA1/CES1/NQO1/ABCC3/BLVRB/TGFB1/SLC6A16/GGTLC2/GGT1/HMOX1/PDGFB | 25 |
| GOBP_RESPONSE_TO_METAL_ION | GOBP_RESPONSE_TO_METAL_ION | GOBP_RESPONSE_TO_METAL_ION | 45/1438 | 350/23056 | 0.1285714 | 2.061434 | 5.160730 | 0.0000033 | 0.0000412 | 0.0000265 | VCAM1/S100A16/PTGS2/ITPKB/IL1A/CYBRD1/CASP8/CPS1/TNNC1/WNT5A/SUCNR1/CLDN1/SOD3/TRPC3/CRHBP/PCSK1/BMP6/TFAP2A/EDN1/HFE/ITPR3/SOD2/AQP1/CAV1/SHH/LOXL2/ADAM9/FABP4/TNFRSF11B/ADCY8/AQP3/AKR1C3/FIBIN/SYT12/ALOX5AP/NFATC4/FOS/CRIP1/THBS1/MT2A/MT1X/NQO1/MBP/PRNP/HMOX1 | 45 |
| GOBP_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | 18/1438 | 84/23056 | 0.2142857 | 3.435724 | 5.767965 | 0.0000034 | 0.0000416 | 0.0000267 | TGFB2/BMP10/ITGB6/PPARG/WWTR1/VEPH1/BMP3/DAB2/BMP6/INHBA/RBPMS/GDF6/BMP4/FOS/SMAD6/GDF15/TGFB1/BMP2 | 18 |
| GOBP_SOMITE_DEVELOPMENT | GOBP_SOMITE_DEVELOPMENT | GOBP_SOMITE_DEVELOPMENT | 18/1438 | 84/23056 | 0.2142857 | 3.435724 | 5.767965 | 0.0000034 | 0.0000416 | 0.0000267 | WNT5A/LEF1/FOXC1/TBX18/SEMA3C/SHH/DMRT2/CRB2/NOTCH1/DKK1/SIX1/SIX4/ALDH1A2/FOXB1/FOXF1/LHX1/MEOX1/NOG | 18 |
| KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | 22/1438 | 118/23056 | 0.1864407 | 2.989274 | 5.587430 | 0.0000034 | 0.0000420 | 0.0000270 | RNASEL/TGFB2/IL1R1/IL1A/WNT5A/CXCL8/EREG/TLR3/GJA1/PERP/IL6/FZD1/CAV1/TNFRSF10A/PLAT/FAS/CASP1/IGFBP6/LUM/MMP2/BMP2/BGN | 22 |
| UDAYAKUMAR_MED1_TARGETS_DN | UDAYAKUMAR_MED1_TARGETS_DN | UDAYAKUMAR_MED1_TARGETS_DN | 35/1438 | 244/23056 | 0.1434426 | 2.299870 | 5.264625 | 0.0000036 | 0.0000441 | 0.0000283 | HSPB7/CDA/RHOC/ELF3/TFPI/ACKR3/AMOTL2/PLK2/PXDC1/BMP6/DDR1/CITED2/GPNMB/EPHB4/RBPMS/KLF4/GSN/DKK1/FAS/DNMBP/ADM/CPM/TNFAIP2/TPM1/FMNL1/COL1A1/GPRC5C/GADD45B/TNFSF9/AXL/KCNN4/MN1/HMOX1/SAT1/SSX2 | 35 |
| GOBP_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 20/1438 | 101/23056 | 0.1980198 | 3.174927 | 5.649642 | 0.0000036 | 0.0000441 | 0.0000284 | TNFRSF1B/TGFB2/NLRP3/IL1R1/IL1B/WNT5A/CD96/BCL6/SPON2/TLR3/F2RL1/HFE/HLA-E/IL6/CD36/ANGPT1/DDX58/APOA1/TGFB1/HMOX1 | 20 |
| REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY | REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY | REACTOME_TNFR2_NON_CANONICAL_NF_KB_PATHWAY | 20/1438 | 101/23056 | 0.1980198 | 3.174927 | 5.649642 | 0.0000036 | 0.0000441 | 0.0000284 | TNFRSF18/TNFRSF4/TNFRSF9/TNFRSF1B/TNFSF18/PSMB8/PSMB9/TNFRSF11B/TNFSF15/NFKB2/BIRC3/TNFRSF1A/TNFSF13B/TNFRSF12A/PSMB10/TNFRSF11A/TNFSF9/CD70/TNFSF14/RELB | 20 |
| GU_PDEF_TARGETS_DN | GU_PDEF_TARGETS_DN | GU_PDEF_TARGETS_DN | 12/1438 | 40/23056 | 0.3000000 | 4.810014 | 6.220079 | 0.0000036 | 0.0000441 | 0.0000284 | TGFB2/ITGB6/VEGFC/FOXC1/ITGB8/KRT7/KRT8/KRT18/FOXO1/THBS1/KRT19/ITGB4 | 12 |
| GOMF_DNA_BINDING_TRANSCRIPTION_ACTIVATOR_ACTIVITY | GOMF_DNA_BINDING_TRANSCRIPTION_ACTIVATOR_ACTIVITY | GOMF_DNA_BINDING_TRANSCRIPTION_ACTIVATOR_ACTIVITY | 55/1438 | 464/23056 | 0.1185345 | 1.900508 | 5.053865 | 0.0000036 | 0.0000446 | 0.0000287 | FOXD2/PRRX1/NR5A2/ELF3/DLX2/MITF/FOXL2/LEF1/FOXD1/SOX30/FOXC1/RREB1/TFAP2A/RUNX2/GCM1/HOXA1/HOXA7/EBF2/CEBPD/PLAG1/MYBL1/DMRT2/GLIS3/KLF4/HHEX/PITX3/NFKB2/WT1/EHF/ALX4/CREB3L1/FOSL1/PGR/STAT6/GLI1/FOXO1/SIX1/SIX4/FOS/ESRRB/BNC1/MAF/FOXF1/MEOX1/HOXB2/HOXB3/HOXB7/DLX3/SOX9/CREB3L3/SIX5/CEBPB/NFATC2/TFAP2C/RUNX1 | 55 |
| SUNG_METASTASIS_STROMA_UP | SUNG_METASTASIS_STROMA_UP | SUNG_METASTASIS_STROMA_UP | 21/1438 | 110/23056 | 0.1909091 | 3.060918 | 5.588018 | 0.0000038 | 0.0000468 | 0.0000301 | AGRN/SPSB1/HSPG2/CRABP2/PTGS2/COL3A1/COL5A2/SEL1L3/PLK2/SPARC/COL12A1/THBS2/COL5A1/MAP3K8/FZD8/ALOX5/DKK1/PLAAT4/EPS8/UACA/SDC4 | 21 |
| REACTOME_INTERFERON_GAMMA_SIGNALING | REACTOME_INTERFERON_GAMMA_SIGNALING | REACTOME_INTERFERON_GAMMA_SIGNALING | 19/1438 | 93/23056 | 0.2043011 | 3.275637 | 5.671322 | 0.0000039 | 0.0000472 | 0.0000303 | GBP3/GBP1/GBP2/GBP4/GBP5/VCAM1/TRIM17/SP100/TRIM38/HLA-E/HLA-C/TRIM5/CD44/OASL/IRF9/MT2A/SOCS3/ICAM1/MID1 | 19 |
| GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS | GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS | GOBP_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS | 46/1438 | 363/23056 | 0.1267218 | 2.031778 | 5.110318 | 0.0000039 | 0.0000472 | 0.0000303 | TNFRSF1B/ZC3H12A/MR1/PLA2G4A/PTPRC/NLRP3/IL1R1/IL1B/BCL6/LEF1/CFI/IL7R/C9/HFE/HLA-E/MICA/TNFAIP3/AHR/IL6/CLU/CD274/ANXA1/NOTCH1/MBL2/NFKB2/C1S/C1R/C1RL/KLRD1/NCKAP1L/STAT6/TNFSF13B/IL4R/IL21R/EBI3/CD70/C3/ICAM1/IL27RA/IL12RB1/TGFB1/PSG9/BCL3/NECTIN2/RELB/IL4I1 | 46 |
| BORLAK_LIVER_CANCER_EGF_UP | BORLAK_LIVER_CANCER_EGF_UP | BORLAK_LIVER_CANCER_EGF_UP | 14/1438 | 54/23056 | 0.2592593 | 4.156802 | 5.989846 | 0.0000039 | 0.0000472 | 0.0000303 | RHOC/S100A11/ELF3/TGFA/SPP1/DDR1/PDGFA/SERPINE1/KRT8/KRT18/SLC7A7/FOS/ANXA2/CLDN7 | 14 |
| WIERENGA_STAT5A_TARGETS_GROUP2 | WIERENGA_STAT5A_TARGETS_GROUP2 | WIERENGA_STAT5A_TARGETS_GROUP2 | 14/1438 | 54/23056 | 0.2592593 | 4.156802 | 5.989846 | 0.0000039 | 0.0000472 | 0.0000303 | BHLHE40/P3H2/CXCL8/SPP1/IL7R/CSF2/TRAF1/PLAU/SLC2A14/EMP1/CCL5/CCR7/GADD45B/KLF2 | 14 |
| ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF | ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF | ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF | 14/1438 | 54/23056 | 0.2592593 | 4.156802 | 5.989846 | 0.0000039 | 0.0000472 | 0.0000303 | ERRFI1/SPOCD1/OSR1/FSTL1/ARL14/GFPT2/PXDC1/CCN2/CITED2/INHBA/CLIC3/TAGLN/BLID/GLIPR1 | 14 |
| RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | 44/1438 | 341/23056 | 0.1290323 | 2.068823 | 5.128389 | 0.0000039 | 0.0000473 | 0.0000304 | TNFRSF4/RUNX3/NIBAN1/HSD11B1/RASGRP3/CRIM1/IL1R1/IL1A/KYNU/SLC12A8/MGLL/LPP/RBM47/SPP1/TNIP3/SLC7A11/ADAM19/GPNMB/INHBA/TNS3/SERPINE1/ST3GAL1/TRAF1/NRP1/RAB38/BIRC3/C1S/LTBP2/CRIP1/ANXA2/IL21R/MMP2/NQO1/CCR7/GADD45B/EBI3/LYPD3/NECTIN2/APOE/TGM2/SDC4/RUNX1/NDP/IL13RA1 | 44 |
| AMIT_EGF_RESPONSE_60_HELA | AMIT_EGF_RESPONSE_60_HELA | AMIT_EGF_RESPONSE_60_HELA | 13/1438 | 47/23056 | 0.2765957 | 4.434765 | 6.079268 | 0.0000039 | 0.0000473 | 0.0000304 | RUNX3/CCN1/BHLHE40/HES1/FOXC1/CCN2/CITED2/SOD2/SERPINE1/GPRC5A/ZFP36L1/TNFAIP2/LIF | 13 |
| GOBP_COLLAGEN_BIOSYNTHETIC_PROCESS | GOBP_COLLAGEN_BIOSYNTHETIC_PROCESS | GOBP_COLLAGEN_BIOSYNTHETIC_PROCESS | 13/1438 | 47/23056 | 0.2765957 | 4.434765 | 6.079268 | 0.0000039 | 0.0000473 | 0.0000304 | ERRFI1/ADAMTS3/ITGA2/CCN2/IL6/COL5A1/CREB3L1/SERPINH1/BMP4/COL1A1/SERPINB7/TGFB1/RUNX1 | 13 |
| GOBP_NEGATIVE_CHEMOTAXIS | GOBP_NEGATIVE_CHEMOTAXIS | GOBP_NEGATIVE_CHEMOTAXIS | 13/1438 | 47/23056 | 0.2765957 | 4.434765 | 6.079268 | 0.0000039 | 0.0000473 | 0.0000304 | LGR6/DPP4/NRP2/SEMA3B/WNT5A/SLIT2/SEMA5A/PDGFA/SEMA3C/SEMA3A/SEMA3D/APOA1/SEMA6B | 13 |
| YAMASHITA_LIVER_CANCER_STEM_CELL_UP | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | 13/1438 | 47/23056 | 0.2765957 | 4.434765 | 6.079268 | 0.0000039 | 0.0000473 | 0.0000304 | ELF3/MYLK/ITGB5/CLDN1/FGFR3/DDR1/SEMA3C/DKK1/TCF7L2/IGF1/GRB7/SOX9/BACE2 | 13 |
| GOBP_CELLULAR_HORMONE_METABOLIC_PROCESS | GOBP_CELLULAR_HORMONE_METABOLIC_PROCESS | GOBP_CELLULAR_HORMONE_METABOLIC_PROCESS | 24/1438 | 137/23056 | 0.1751825 | 2.808767 | 5.476453 | 0.0000039 | 0.0000473 | 0.0000304 | DHRS3/ECE1/RPE65/CRABP2/SRD5A2/CYP26B1/UGT2B7/SULT1E1/SPP1/DAB2/BMP6/AKR1B10/AKR1B15/SHH/AKR1C3/CYP26A1/ADM/EDNRB/CYP46A1/CYP19A1/ALDH1A2/ALDH1A3/IL4I1/BMP2 | 24 |
| PID_P53_DOWNSTREAM_PATHWAY | PID_P53_DOWNSTREAM_PATHWAY | PID_P53_DOWNSTREAM_PATHWAY | 24/1438 | 137/23056 | 0.1751825 | 2.808767 | 5.476453 | 0.0000039 | 0.0000473 | 0.0000304 | EPHA2/EDN2/S100A2/TGFA/CASP10/BCL6/SPP1/RNF144B/PERP/SERPINE1/CAV1/MET/TNFRSF10C/TNFRSF10A/DKK1/AIFM2/FAS/CD82/CASP1/BCL2A1/MMP2/GDF15/COL18A1/LIF | 24 |
| RODRIGUES_DCC_TARGETS_DN | RODRIGUES_DCC_TARGETS_DN | RODRIGUES_DCC_TARGETS_DN | 22/1438 | 119/23056 | 0.1848739 | 2.964154 | 5.540322 | 0.0000039 | 0.0000477 | 0.0000306 | NR5A2/TGFB2/BCL6/MYO10/IQGAP2/ERAP2/PSMB9/RUNX2/UTRN/AHR/HOXA3/GSN/NRP1/CD44/CD82/VWA5A/SCNN1A/EPS8/NUPR1/MBP/MID1/GPC4 | 22 |
| ENGELMANN_CANCER_PROGENITORS_DN | ENGELMANN_CANCER_PROGENITORS_DN | ENGELMANN_CANCER_PROGENITORS_DN | 16/1438 | 69/23056 | 0.2318841 | 3.717885 | 5.831345 | 0.0000040 | 0.0000478 | 0.0000307 | FN1/FGFR3/CCN2/GSN/CLIC3/AKR1C3/ANXA8L1/CD44/BMP4/IL4R/OSGIN1/HS3ST3A1/KRT13/ABCC3/GADD45B/KLK6 | 16 |
| RODRIGUES_THYROID_CARCINOMA_DN | RODRIGUES_THYROID_CARCINOMA_DN | RODRIGUES_THYROID_CARCINOMA_DN | 17/1438 | 77/23056 | 0.2207792 | 3.539837 | 5.757579 | 0.0000041 | 0.0000493 | 0.0000317 | S100A2/NABP1/FN1/COL8A1/PHLDB2/CLDN1/CXCL1/PTPRK/ITGB8/SAMD9/SRGN/CD44/SYTL2/AMIGO2/THBS1/THBD/LIF | 17 |
| GOBP_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | GOBP_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | GOBP_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | 29/1438 | 185/23056 | 0.1567568 | 2.513341 | 5.330086 | 0.0000042 | 0.0000501 | 0.0000322 | TNFRSF18/TNFSF18/PTPRC/AGT/NMI/PPARG/PARP14/HES1/FGFR3/EGF/IL15/IL7R/IL31RA/TSLP/CSF2/IL6/CAV1/IFNE/NOTCH1/TNFRSF1A/STAT6/IGF1/FLT3/CTF1/CCL5/SOCS3/TGFB1/BCL3/LIF | 29 |
| GOCC_ENDOCYTIC_VESICLE | GOCC_ENDOCYTIC_VESICLE | GOCC_ENDOCYTIC_VESICLE | 44/1438 | 342/23056 | 0.1286550 | 2.062774 | 5.106948 | 0.0000042 | 0.0000507 | 0.0000326 | LDLRAP1/CTSS/RAB7B/TGFA/DPP4/STAB1/WNT5A/ITGB5/PLD1/EPGN/EREG/BTC/ANXA3/EGF/IL7R/HBEGF/ADRB2/SPARC/HLA-E/HLA-C/TAPBP/CD36/CAV1/ATP6V0A4/ZYX/MSR1/GSN/SFTPD/SAA1/FZD4/RAB38/APOA1/RAB20/EHD4/MYO1E/CSF3/FMNL1/COLEC12/ELANE/APOE/EHD2/RIN2/RAC2/WNT7B | 44 |
| IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | 32/1438 | 215/23056 | 0.1488372 | 2.386363 | 5.267360 | 0.0000042 | 0.0000507 | 0.0000326 | TIE1/PRRX1/CRIM1/TWIST2/LAMB2/FSTL1/PLSCR4/LPP/HES1/TMEM144/HBEGF/FILIP1/VNN1/UTRN/HOXA3/MET/PTPRZ1/ZNF467/ANGPT1/C9orf152/TRAF1/BCL9L/KRT7/CGNL1/LACTB/MYOM1/DSG2/SIX5/RRAS/PROCR/BACE2/COL18A1 | 32 |
| HP_SKIN_NODULE | HP_SKIN_NODULE | HP_SKIN_NODULE | 20/1438 | 102/23056 | 0.1960784 | 3.143800 | 5.596408 | 0.0000042 | 0.0000507 | 0.0000326 | ECM1/COL3A1/COL5A2/COL7A1/BCL6/TNFRSF11B/TEK/COL5A1/FAS/FGFR2/HMGA2/MMP14/DACT1/FBN1/SALL1/MMP2/COL1A1/TNFRSF11A/APOE/PDGFB | 20 |
| GOBP_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | GOBP_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | GOBP_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 47/1438 | 376/23056 | 0.1250000 | 2.004173 | 5.063315 | 0.0000044 | 0.0000533 | 0.0000343 | PTPN22/PTPRC/ATP2B4/LAX1/AGT/TGFA/IL1B/EPHA4/PPARG/WNT5A/HEG1/EPGN/EGF/PDGFC/DAB2/CCNO/ADRB2/FGF18/EDN1/TPD52L1/TNFAIP3/SASH1/PDGFA/CAV1/ARHGEF5/ADAM9/TCIM/FZD8/DKK1/HHEX/PTPRJ/FZD4/HMGA2/LATS2/FLT3/FLT1/AJUBA/BMP4/THBS1/MYOCD/TNFRSF11A/ELANE/TGFB1/APOE/BMP2/PDGFB/TENM1 | 47 |
| GOBP_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | 21/1438 | 111/23056 | 0.1891892 | 3.033342 | 5.538373 | 0.0000044 | 0.0000533 | 0.0000343 | TGFBR2/SEMA3B/WNT5A/OSTN/FGFR3/PLAC8/SPP1/SEMA5A/ADRB2/CITED2/SEMA3C/SEMA3A/SEMA3D/NRP1/MYOZ1/TLL2/BMP4/NOG/SEMA6B/GDF15/MAG | 21 |
| GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION | 21/1438 | 111/23056 | 0.1891892 | 3.033342 | 5.538373 | 0.0000044 | 0.0000533 | 0.0000343 | ECM1/ITGA4/NRP2/CCR3/WNT5A/KDR/EGF/VEGFC/SEMA5A/BMP6/CCL26/CAV2/TEK/JCAD/NRP1/PRKD1/BMP4/CDH13/BMP2/HMOX1/PDGFB | 21 |
| GOBP_NEGATIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | GOBP_NEGATIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | GOBP_NEGATIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | 7/1438 | 13/23056 | 0.5384615 | 8.633358 | 7.100224 | 0.0000044 | 0.0000533 | 0.0000343 | TNFRSF1B/DPP4/FAP/ADTRP/NOTCH1/TNFRSF1A/TGFB1 | 7 |
| XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP | 7/1438 | 13/23056 | 0.5384615 | 8.633358 | 7.100224 | 0.0000044 | 0.0000533 | 0.0000343 | SPSB1/ECM1/FOXD1/F2RL1/MMP10/LTBP2/TGM2 | 7 |
| HP_ABDOMINAL_DISTENTION | HP_ABDOMINAL_DISTENTION | HP_ABDOMINAL_DISTENTION | 22/1438 | 120/23056 | 0.1833333 | 2.939453 | 5.493704 | 0.0000045 | 0.0000544 | 0.0000350 | LMOD1/ACTG2/ITGA6/MYLK/NKX3-2/SPP1/PSMB8/BMPER/EPHB4/SLC26A4/TNFSF15/WT1/KRT8/KRT18/FREM2/PYGL/EPB42/FBN1/ITGB4/CACNA1A/IL12RB1/MYL9 | 22 |
| REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | 19/1438 | 94/23056 | 0.2021277 | 3.240789 | 5.614543 | 0.0000046 | 0.0000545 | 0.0000350 | PTCH2/WNT9A/SCTR/VIPR1/UCN2/WNT5A/CRHBP/FZD1/SHH/FZD6/FZD8/ADM/FZD4/WNT10B/GLP2R/GIP/GNGT2/ADGRE1/WNT7B | 19 |
| HP_NAIL_DYSPLASIA | HP_NAIL_DYSPLASIA | HP_NAIL_DYSPLASIA | 26/1438 | 157/23056 | 0.1656051 | 2.655209 | 5.367212 | 0.0000046 | 0.0000553 | 0.0000355 | ECE1/LAMC2/LAMB3/ITGA6/IL17RC/COL7A1/WNT5A/FGFRL1/FGFR3/VEGFC/DSP/TFAP2A/HLA-C/GJA1/GLI3/FZD6/TRPS1/NFKB2/FGFR2/MMP1/GLI1/BMP4/KRT17/ITGB4/BMP2/GPC4 | 26 |
| GOBP_SEMI_LUNAR_VALVE_DEVELOPMENT | GOBP_SEMI_LUNAR_VALVE_DEVELOPMENT | GOBP_SEMI_LUNAR_VALVE_DEVELOPMENT | 12/1438 | 41/23056 | 0.2926829 | 4.692697 | 6.103575 | 0.0000048 | 0.0000573 | 0.0000369 | TNFRSF1B/TIE1/TGFB2/SLIT2/NOTCH1/TNFRSF1A/BMP4/SMAD6/SOX9/TGFB1/BMP2/GATA5 | 12 |
| HP_MULTIFACTORIAL_INHERITANCE | HP_MULTIFACTORIAL_INHERITANCE | HP_MULTIFACTORIAL_INHERITANCE | 18/1438 | 86/23056 | 0.2093023 | 3.355824 | 5.645023 | 0.0000048 | 0.0000573 | 0.0000369 | ECE1/CFH/AGT/HNMT/PPARG/ADRB2/HLA-C/PLA2G7/GJA1/IL6/GDF6/ALOX5/SERPINH1/FLT3/ALOX5AP/BMP4/PTGIS/APOL1 | 18 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | 18/1438 | 86/23056 | 0.2093023 | 3.355824 | 5.645023 | 0.0000048 | 0.0000573 | 0.0000369 | PLA2G4A/DLX2/CAVIN2/JCHAIN/INPP4B/GASK1B/CDH9/IL7R/EDN1/ITGB8/HOXA3/SEMA3C/TSPAN12/MS4A4A/GLIPR1/FLT3/FRMD6/HOXB3 | 18 |
| GOLDRATH_ANTIGEN_RESPONSE | GOLDRATH_ANTIGEN_RESPONSE | GOLDRATH_ANTIGEN_RESPONSE | 46/1438 | 366/23056 | 0.1256831 | 2.015124 | 5.048900 | 0.0000048 | 0.0000575 | 0.0000370 | TNFRSF9/ERRFI1/S100A10/S100A11/S100A13/CAPG/TMEM37/ITGA4/SP100/BHLHE40/IGSF10/JCHAIN/ELL2/HLA-E/IER3/RUNX2/CRYBG1/PERP/CITED2/SKAP2/MDFIC/CA1/ANXA1/NRP1/VCL/BAG3/IFITM3/HBD/CD44/AHNAK/CASP1/KLRC4-KLRK1/YBX3/EMP1/ANXA2/BCL2A1/MT1X/CD68/CCL5/MYL4/GADD45B/C3/ADGRE1/IL12RB1/EMP3/LGALS1 | 46 |
| GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 16/1438 | 70/23056 | 0.2285714 | 3.664773 | 5.758796 | 0.0000048 | 0.0000575 | 0.0000370 | CSF1/PLA2G4A/COL3A1/COL5A2/FN1/PPIC/EDN1/CCN2/PDGFA/INHBA/SERPINE1/CLU/IL4R/COL1A1/GADD45B/COL18A1 | 16 |
| DURAND_STROMA_NS_UP | DURAND_STROMA_NS_UP | DURAND_STROMA_NS_UP | 27/1438 | 167/23056 | 0.1616766 | 2.592223 | 5.326022 | 0.0000049 | 0.0000579 | 0.0000372 | FBLIM1/BRINP3/OSR1/GPR39/RBM47/HLA-E/SASH1/RBPMS/DMRT2/S1PR3/KLF4/PRRG4/CRYAB/GPRC5A/H2AJ/GLIPR1/TNFSF13B/CA12/BNC1/MT1X/KRT19/LLGL2/SLC16A3/GATA6/TNFSF9/GDF15/MYL9 | 27 |
| HP_DILATED_CARDIOMYOPATHY | HP_DILATED_CARDIOMYOPATHY | HP_DILATED_CARDIOMYOPATHY | 27/1438 | 167/23056 | 0.1616766 | 2.592223 | 5.326022 | 0.0000049 | 0.0000579 | 0.0000372 | MMP23B/HSPG2/NEXN/HJV/LAMC2/LAMB3/DES/COL7A1/TNNC1/DSP/CAP2/LAMA4/TRDN/TPM2/MYPN/VCL/ANKRD1/BAG3/MMP1/CRYAB/ACTC1/TPM1/JUP/KCNJ2/DSG2/JPH2/GATA5 | 27 |
| ODONNELL_TFRC_TARGETS_UP | ODONNELL_TFRC_TARGETS_UP | ODONNELL_TFRC_TARGETS_UP | 52/1438 | 434/23056 | 0.1198157 | 1.921050 | 4.995936 | 0.0000049 | 0.0000580 | 0.0000373 | SPOCD1/MR1/IGFN1/WNT9A/NID1/DLX2/TFPI/CASP10/MYLK/CLDN1/TMEM156/INPP4B/PLK2/PPIC/SLC22A23/RNF144B/VNN1/FAM20C/SCIN/NIPAL2/PAPPA/PTGS1/ALOX5/ANXA8/PLAC9/FAS/CD44/PLAAT4/C1RL/GLIPR1/TPCN1/SIX1/ZFP36L1/SERPINA1/THBS1/CYP19A1/IL4R/RRAD/MYH1/HOXB13/ABCC3/WIPI1/LLGL2/GADD45B/TNFSF9/CACNA1A/CD37/TFAP2C/BIRC7/APOBEC3G/SAT1/IL13RA1 | 52 |
| GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 34/1438 | 237/23056 | 0.1434599 | 2.300147 | 5.188869 | 0.0000049 | 0.0000580 | 0.0000373 | TNFRSF1B/MR1/PTPRC/NLRP3/IL1R1/IL1B/CD96/BCL6/CXCL6/TLR3/IL7R/F2RL1/HFE/HLA-E/MICA/RAET1E/AHR/IL6/DDX58/KLRD1/KLRC4-KLRK1/NCKAP1L/STAT6/IL4R/FOXF1/C3/ICAM1/IL27RA/IL12RB1/TGFB1/NECTIN2/IL4I1/HMOX1/RAC2 | 34 |
| GOBP_MACROPHAGE_MIGRATION | GOBP_MACROPHAGE_MIGRATION | GOBP_MACROPHAGE_MIGRATION | 14/1438 | 55/23056 | 0.2545455 | 4.081224 | 5.900455 | 0.0000049 | 0.0000580 | 0.0000373 | EDN2/MCOLN2/CSF1/RARRES2/TRIM55/SFTPD/SAA1/C3AR1/EDNRB/MMP14/THBS1/CYP19A1/CCL5/C5AR1 | 14 |
| WP_NRP1TRIGGERED_SIGNALING_PATHWAYS_IN_PANCREATIC_CANCER | WP_NRP1TRIGGERED_SIGNALING_PATHWAYS_IN_PANCREATIC_CANCER | WP_NRP1TRIGGERED_SIGNALING_PATHWAYS_IN_PANCREATIC_CANCER | 14/1438 | 55/23056 | 0.2545455 | 4.081224 | 5.900455 | 0.0000049 | 0.0000580 | 0.0000373 | TGFB2/TGFBR2/KDR/EGF/CCN2/SEMA3A/MET/NRP1/NFKB2/FLT1/MMP2/COL1A1/TGFB1/RELB | 14 |
| BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | 13/1438 | 48/23056 | 0.2708333 | 4.342374 | 5.978475 | 0.0000051 | 0.0000596 | 0.0000383 | VCAM1/CSF1/COL5A2/AMOTL2/LPP/SPARC/EXT1/NRP1/VCL/PRSS23/ACTC1/TPM1/MYH9 | 13 |
| DAUER_STAT3_TARGETS_DN | DAUER_STAT3_TARGETS_DN | DAUER_STAT3_TARGETS_DN | 13/1438 | 48/23056 | 0.2708333 | 4.342374 | 5.978475 | 0.0000051 | 0.0000596 | 0.0000383 | SP110/DDX60/TLR3/SAMD9/PDK4/PARP12/DDX58/AQP3/TRIM5/OASL/IFI35/MX1/USP18 | 13 |
| GOBP_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT | 13/1438 | 48/23056 | 0.2708333 | 4.342374 | 5.978475 | 0.0000051 | 0.0000596 | 0.0000383 | VCAM1/NRP2/FN1/ACKR3/HES1/GDNF/TFAP2A/SEMA3A/NRP1/EDNRB/SIX1/SOX8/HOXB2 | 13 |
| GOBP_REGULATION_OF_PLATELET_ACTIVATION | GOBP_REGULATION_OF_PLATELET_ACTIVATION | GOBP_REGULATION_OF_PLATELET_ACTIVATION | 13/1438 | 48/23056 | 0.2708333 | 4.342374 | 5.978475 | 0.0000051 | 0.0000596 | 0.0000383 | PLA2G4A/SERPINE2/TXK/TEC/PDGFA/IL6/UBASH3B/ADAMTS18/C1QTNF1/EMILIN2/APOE/THBD/PDGFB | 13 |
| GOBP_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | GOBP_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | GOBP_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 21/1438 | 112/23056 | 0.1875000 | 3.006259 | 5.489283 | 0.0000051 | 0.0000607 | 0.0000390 | ZC3H12A/PTPRC/TGFB2/CD96/BCL6/IL7R/HFE/HLA-E/MICA/AHR/ANGPT1/ANXA1/APOA1/KLRD1/NCKAP1L/IL4R/FOXF1/CD22/TGFB1/IL4I1/HMOX1 | 21 |
| GOBP_INTERLEUKIN_1_PRODUCTION | GOBP_INTERLEUKIN_1_PRODUCTION | GOBP_INTERLEUKIN_1_PRODUCTION | 23/1438 | 130/23056 | 0.1769231 | 2.836675 | 5.416192 | 0.0000052 | 0.0000612 | 0.0000394 | ERRFI1/ZC3H12A/GBP5/S100A13/IFI16/NLRP3/CASP8/WNT5A/F2RL1/SERPINB1/TNFAIP3/IL6/CD36/GSDMD/ANXA1/S1PR3/SAA1/CASP1/CARD16/APOA1/IGF1/CCR7/SIRPA | 23 |
| SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | 30/1438 | 197/23056 | 0.1522843 | 2.441631 | 5.240986 | 0.0000052 | 0.0000612 | 0.0000394 | S100A13/MR1/ATP2B4/MAP1LC3C/EFEMP1/VAMP5/GPR39/CAVIN2/SLC34A2/BMP3/CDS1/ADGRF5/CITED2/PON3/RBPMS/CEBPD/AQP3/SFTPD/ALDH3B1/RAB38/GPRC5A/TNS2/CPM/NFKBIA/LTK/ICAM1/IL27RA/SLC7A10/PSG4/PLS3 | 30 |
| GOBP_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_ALPHA_BETA_T_CELL_ACTIVATION | 26/1438 | 158/23056 | 0.1645570 | 2.638404 | 5.329728 | 0.0000052 | 0.0000613 | 0.0000394 | RUNX3/ZC3H12A/PTPN22/PTPRC/ITPKB/NLRP3/TGFBR2/BCL6/LEF1/IL15/DOCK2/HFE/HLA-E/IL6/GLI3/SHH/CD274/ANXA1/NCKAP1L/STAT6/IL4R/EBI3/IL12RB1/BCL3/RELB/RUNX1 | 26 |
| HP_ABNORMALITY_OF_BLOOD_CIRCULATION | HP_ABNORMALITY_OF_BLOOD_CIRCULATION | HP_ABNORMALITY_OF_BLOOD_CIRCULATION | 42/1438 | 323/23056 | 0.1300310 | 2.084836 | 5.063970 | 0.0000053 | 0.0000619 | 0.0000398 | PTPN22/HMCN1/CFH/TGFB2/EFEMP1/COL3A1/NABP1/CASP10/FN1/SP110/TGFBR2/MYLK/SLCO2A1/CFI/ITGA2/SPARC/RREB1/CD109/TENT5A/CITED2/SAMD9/SERPINE1/TSPAN12/TEK/NOTCH1/PLAU/FAS/FZD4/VWF/TNFRSF1A/SLC7A7/ACTC1/FBN1/FOXF1/RHBDF2/GATA6/PLVAP/APOE/RUNX1/USP18/PDGFB/NDP | 42 |
| JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | 42/1438 | 323/23056 | 0.1300310 | 2.084836 | 5.063970 | 0.0000053 | 0.0000619 | 0.0000398 | PLA2G4A/CFH/CD34/CRIM1/TFPI/PDGFC/NPR3/IQGAP2/F2RL1/CRHBP/MZB1/RUNX2/SLC25A27/TNFRSF21/CD109/TMEM200A/ADGRG6/HOXA3/TNS3/TRIP6/MEST/ADAM28/RBPMS/ASPH/CTHRC1/ANGPT1/COL5A1/AKR1C3/HHEX/EMP1/PPM1H/MSRB3/HMGA2/FLT3/FRMD6/ITPRIPL2/JUP/HOXB3/ACSF2/DSG2/PLS3/SLITRK4 | 42 |
| HP_LIMITATION_OF_JOINT_MOBILITY | HP_LIMITATION_OF_JOINT_MOBILITY | HP_LIMITATION_OF_JOINT_MOBILITY | 49/1438 | 401/23056 | 0.1221945 | 1.959191 | 4.997462 | 0.0000053 | 0.0000621 | 0.0000399 | MMP23B/HSPG2/PTPN22/TBX15/ADAMTSL4/PRG4/ACTG2/FN1/COL6A3/LAMB2/CD96/SLCO2A1/FGFR3/STING1/ADAMTS2/TFAP2A/HFE/PSMB8/COL12A1/LAMA2/PERP/ADGRG6/TMEM270/FLNC/SHH/CSGALNACT1/EXT1/TNFRSF11B/COLEC10/TPM2/DKK1/FGFR2/ITGA7/LTBP2/FBN1/SMAD6/MMP2/MAF/MYH8/SGCA/COL1A1/NOG/PIEZO2/SCN1B/TGFB1/COL9A3/COL6A2/IL2RB/BGN | 49 |
| HP_ABNORMAL_SKIN_MORPHOLOGY_OF_THE_PALM | HP_ABNORMAL_SKIN_MORPHOLOGY_OF_THE_PALM | HP_ABNORMAL_SKIN_MORPHOLOGY_OF_THE_PALM | 47/1438 | 379/23056 | 0.1240106 | 1.988308 | 5.003495 | 0.0000055 | 0.0000645 | 0.0000415 | TNFRSF1B/PTCH2/NEXN/KCNN3/LAMC2/LAMB3/DES/COL7A1/TNNC1/CD96/SLCO2A1/FGFRL1/FGFR3/DOK7/DSP/TFAP2A/CAP2/LAMA4/GJA1/PERP/SASH1/CSGALNACT1/TRPS1/EXT1/COL14A1/TPM2/MYPN/VCL/ANKRD1/BAG3/FGFR2/CRYAB/C1R/IGF1/BMP4/ACTC1/TPM1/KRT17/JUP/DLX4/NOG/ITGB4/RHBDF2/PIEZO2/DSG2/SERPINB7/RIN2 | 47 |
| NABA_PROTEOGLYCANS | NABA_PROTEOGLYCANS | NABA_PROTEOGLYCANS | 11/1438 | 35/23056 | 0.3142857 | 5.039062 | 6.167465 | 0.0000055 | 0.0000648 | 0.0000417 | HSPG2/PODN/PRG4/PRELP/OPTC/HAPLN1/SRGN/EPYC/LUM/HAPLN3/BGN | 11 |
| ANDERSEN_CHOLANGIOCARCINOMA_CLASS1 | ANDERSEN_CHOLANGIOCARCINOMA_CLASS1 | ANDERSEN_CHOLANGIOCARCINOMA_CLASS1 | 15/1438 | 63/23056 | 0.2380952 | 3.817471 | 5.775455 | 0.0000056 | 0.0000649 | 0.0000417 | NUAK2/PTPN14/SCTR/VEPH1/TMEM156/CXCL6/SPP1/HKDC1/ANKRD1/LOXL4/FGFR2/SYT12/PAQR5/TNFRSF12A/PIEZO2 | 15 |
| BURTON_ADIPOGENESIS_PEAK_AT_0HR | BURTON_ADIPOGENESIS_PEAK_AT_0HR | BURTON_ADIPOGENESIS_PEAK_AT_0HR | 15/1438 | 63/23056 | 0.2380952 | 3.817471 | 5.775455 | 0.0000056 | 0.0000649 | 0.0000417 | CSF1/COL8A1/SPP1/VEGFC/DAB2/THBS2/PLAT/GAS1/APBB1IP/CRYAB/IGF1/TPM1/PSMB10/KLF2/MYL9 | 15 |
| GOBP_RESPONSE_TO_FATTY_ACID | GOBP_RESPONSE_TO_FATTY_ACID | GOBP_RESPONSE_TO_FATTY_ACID | 15/1438 | 63/23056 | 0.2380952 | 3.817471 | 5.775455 | 0.0000056 | 0.0000649 | 0.0000417 | ZC3H12A/PTGS2/CPS1/CLDN1/HES1/PCSK1/EDN1/CCN2/CD36/PDK4/PLAT/AKR1C3/FOXO1/SOX9/MBP | 15 |
| GOBP_RESPONSE_TO_PEPTIDE | GOBP_RESPONSE_TO_PEPTIDE | GOBP_RESPONSE_TO_PEPTIDE | 57/1438 | 494/23056 | 0.1153846 | 1.850005 | 4.925503 | 0.0000056 | 0.0000649 | 0.0000417 | C1QTNF12/ERRFI1/RPE65/VCAM1/PTPN22/PTGS2/AGT/SRD5A2/IL1B/ITGA4/COL3A1/CPS1/EPHA4/PPARG/EREG/CRHBP/PCSK1/MZB1/ADRB2/EDN1/GJA1/CCN2/TNFAIP3/CD36/PDK4/CAV2/CAV1/RARRES2/PLAT/ADCY8/ANXA1/NOTCH1/PTPRE/ADM/MMP3/CASP4/TNS2/STAT6/IGF1/FOXO1/EDNRB/NFKBIA/ZFP36L1/SLC24A4/FBN1/MMP2/GLP2R/GRB7/GIP/COL1A1/SOCS3/ICAM1/CACNA1A/KLF2/GDF15/PRNP/PNPLA3 | 57 |
| AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN | AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_DN | 8/1438 | 18/23056 | 0.4444444 | 7.125947 | 6.705657 | 0.0000056 | 0.0000649 | 0.0000417 | CDA/HSPG2/TFPI/PLAC8/AQP3/PTGS1/GPRC5A/KRT13 | 8 |
| GOBP_BRANCH_ELONGATION_OF_AN_EPITHELIUM | GOBP_BRANCH_ELONGATION_OF_AN_EPITHELIUM | GOBP_BRANCH_ELONGATION_OF_AN_EPITHELIUM | 8/1438 | 18/23056 | 0.4444444 | 7.125947 | 6.705657 | 0.0000056 | 0.0000649 | 0.0000417 | WNT5A/SHH/FGFR2/YAP1/BMP4/SIX1/SIX4/SOX9 | 8 |
| GOBP_NOTOCHORD_DEVELOPMENT | GOBP_NOTOCHORD_DEVELOPMENT | GOBP_NOTOCHORD_DEVELOPMENT | 8/1438 | 18/23056 | 0.4444444 | 7.125947 | 6.705657 | 0.0000056 | 0.0000649 | 0.0000417 | EPHA2/WNT5A/CRB2/COL13A1/YAP1/GLI1/NOG/SOX9 | 8 |
| GOBP_TRACHEA_DEVELOPMENT | GOBP_TRACHEA_DEVELOPMENT | GOBP_TRACHEA_DEVELOPMENT | 8/1438 | 18/23056 | 0.4444444 | 7.125947 | 6.705657 | 0.0000056 | 0.0000649 | 0.0000417 | TGFBR2/LEF1/SHH/RSPO2/BMP4/FOXF1/SOX9/WNT7B | 8 |
| GOMF_HEPARAN_SULFATE_PROTEOGLYCAN_BINDING | GOMF_HEPARAN_SULFATE_PROTEOGLYCAN_BINDING | GOMF_HEPARAN_SULFATE_PROTEOGLYCAN_BINDING | 8/1438 | 18/23056 | 0.4444444 | 7.125947 | 6.705657 | 0.0000056 | 0.0000649 | 0.0000417 | AGRN/CFH/PTPRC/SEMA5A/ITGA2/FST/FGF20/APOE | 8 |
| KOBAYASHI_EGFR_SIGNALING_6HR_DN | KOBAYASHI_EGFR_SIGNALING_6HR_DN | KOBAYASHI_EGFR_SIGNALING_6HR_DN | 8/1438 | 18/23056 | 0.4444444 | 7.125947 | 6.705657 | 0.0000056 | 0.0000649 | 0.0000417 | EPHA2/CCN1/TGFA/IER3/PHLDA2/FOSL1/HMGA2/IL11 | 8 |
| GOBP_REGULATION_OF_REPRODUCTIVE_PROCESS | GOBP_REGULATION_OF_REPRODUCTIVE_PROCESS | GOBP_REGULATION_OF_REPRODUCTIVE_PROCESS | 28/1438 | 178/23056 | 0.1573034 | 2.522105 | 5.257748 | 0.0000056 | 0.0000654 | 0.0000421 | IL1A/WNT5A/TCP11/GCM1/GJA1/CITED2/INHBA/SEMA3A/STRA8/SHH/PLAT/SULF1/ZFPM2/B4GALT1/PAEP/NOTCH1/PHLDA2/WT1/ARHGDIB/IGF1/EDNRB/BMP4/SERPINA10/BNC1/NUPR1/SOX9/LIF/MYH9 | 28 |
| GOBP_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | GOBP_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | GOBP_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN | 18/1438 | 87/23056 | 0.2068966 | 3.317251 | 5.584906 | 0.0000057 | 0.0000662 | 0.0000425 | TNFRSF18/TNFSF18/PARP14/HES1/FGFR3/IL15/IL31RA/TSLP/CSF2/IL6/CAV1/TNFRSF1A/IGF1/FLT3/CTF1/CCL5/SOCS3/LIF | 18 |
| HP_ENAMEL_HYPOPLASIA | HP_ENAMEL_HYPOPLASIA | HP_ENAMEL_HYPOPLASIA | 18/1438 | 87/23056 | 0.2068966 | 3.317251 | 5.584906 | 0.0000057 | 0.0000662 | 0.0000425 | LAMC2/LAMB3/TGFA/ITGB6/GALNT3/ITGA6/COL7A1/CLDN1/FGFR3/RUNX2/GJA1/FAM20C/FGFR2/MMP1/WNT10B/DLX3/KCNJ2/ITGB4 | 18 |
| CADWELL_ATG16L1_TARGETS_UP | CADWELL_ATG16L1_TARGETS_UP | CADWELL_ATG16L1_TARGETS_UP | 20/1438 | 104/23056 | 0.1923077 | 3.083342 | 5.491883 | 0.0000057 | 0.0000664 | 0.0000427 | CCDC80/SUCNR1/CXCL2/CFI/NPR3/VNN1/CD36/AKR1B10/FABP4/CA3/HBD/SAA1/SLC5A12/APOA1/SERPINA10/LTK/SOCS3/C1QTNF1/PLIN4/GGT1 | 20 |
| GOBP_MUSCLE_CELL_MIGRATION | GOBP_MUSCLE_CELL_MIGRATION | GOBP_MUSCLE_CELL_MIGRATION | 20/1438 | 104/23056 | 0.1923077 | 3.083342 | 5.491883 | 0.0000057 | 0.0000664 | 0.0000427 | S100A11/AGT/SLIT2/ITGA2/DDR1/PDGFA/SERPINE1/PLAT/HAS2/CCN4/ANXA1/NRP1/PLAU/IGF1/SIX1/SIX4/TPM1/MYOCD/CCL5/PDGFB | 20 |
| HP_SUPRAVENTRICULAR_ARRHYTHMIA | HP_SUPRAVENTRICULAR_ARRHYTHMIA | HP_SUPRAVENTRICULAR_ARRHYTHMIA | 20/1438 | 104/23056 | 0.1923077 | 3.083342 | 5.491883 | 0.0000057 | 0.0000664 | 0.0000427 | NEXN/DES/TNNC1/MYOZ2/TRDN/CITED2/SEMA3A/FLNC/MYPN/KCNA5/SCNN1A/ACTC1/HCN4/CAVIN1/MYL4/KCNJ2/GATA6/SCN1B/BMP2/GATA5 | 20 |
| HOELZEL_NF1_TARGETS_UP | HOELZEL_NF1_TARGETS_UP | HOELZEL_NF1_TARGETS_UP | 24/1438 | 140/23056 | 0.1714286 | 2.748579 | 5.352223 | 0.0000058 | 0.0000665 | 0.0000428 | S100A10/S100A2/IFI16/SEL1L3/FAM114A1/ITGA2/PLK2/RBM24/TENT5A/PDGFA/SERPINE1/MET/PAPPA/NACC2/FAS/PHLDA2/MAML2/EPS8/DRAM1/AHNAK2/HS3ST3A1/GDF15/CEBPB/PLS3 | 24 |
| GOBP_HYALURONAN_METABOLIC_PROCESS | GOBP_HYALURONAN_METABOLIC_PROCESS | GOBP_HYALURONAN_METABOLIC_PROCESS | 10/1438 | 29/23056 | 0.3448276 | 5.528752 | 6.293802 | 0.0000058 | 0.0000666 | 0.0000428 | IL1B/ITIH3/EGF/IL15/HAS2/CEMIP2/CD44/TGFB1/HAS1/PDGFB | 10 |
| GOBP_PHARYNGEAL_SYSTEM_DEVELOPMENT | GOBP_PHARYNGEAL_SYSTEM_DEVELOPMENT | GOBP_PHARYNGEAL_SYSTEM_DEVELOPMENT | 10/1438 | 29/23056 | 0.3448276 | 5.528752 | 6.293802 | 0.0000058 | 0.0000666 | 0.0000428 | ECE1/TGFB2/HES1/EDN1/ADGRF5/HOXA2/BMP4/SIX1/SIX4/NOG | 10 |
| GOBP_REGULATION_OF_VIRAL_PROCESS | GOBP_REGULATION_OF_VIRAL_PROCESS | GOBP_REGULATION_OF_VIRAL_PROCESS | 26/1438 | 159/23056 | 0.1635220 | 2.621811 | 5.292534 | 0.0000059 | 0.0000675 | 0.0000434 | IFI16/RNASEL/NR5A2/CXCL8/TRIML2/TRIML1/TRIM38/MDFIC/PARP10/GSN/NOTCH1/MBL2/IFITM2/IFITM3/TRIM5/HMGA2/OASL/CCL5/ZFP36/AXL/NECTIN2/MX1/LGALS1/APOBEC3A/APOBEC3G/APOBEC3H | 26 |
| HP_GLOMERULONEPHRITIS | HP_GLOMERULONEPHRITIS | HP_GLOMERULONEPHRITIS | 16/1438 | 71/23056 | 0.2253521 | 3.613156 | 5.687567 | 0.0000059 | 0.0000676 | 0.0000435 | PTPN22/FCGR2A/CASP10/COL7A1/MME/ARHGAP24/CFI/CRB2/FAS/WT1/MMP1/SLC7A7/MYO1E/C3/APOL1/TBC1D8B | 16 |
| BASSO_HAIRY_CELL_LEUKEMIA_UP | BASSO_HAIRY_CELL_LEUKEMIA_UP | BASSO_HAIRY_CELL_LEUKEMIA_UP | 17/1438 | 79/23056 | 0.2151899 | 3.450221 | 5.626345 | 0.0000059 | 0.0000677 | 0.0000435 | S100A13/IL1R1/SUSD5/WWTR1/ARAP2/PPIC/ANXA1/MYOF/TCF7L2/PRSS23/TNFRSF1A/EMP1/FLT3/THBS1/MAF/RRAS/RIN2 | 17 |
| GOBP_ASTROCYTE_DIFFERENTIATION | GOBP_ASTROCYTE_DIFFERENTIATION | GOBP_ASTROCYTE_DIFFERENTIATION | 17/1438 | 79/23056 | 0.2151899 | 3.450221 | 5.626345 | 0.0000059 | 0.0000677 | 0.0000435 | IL1B/EPHA4/SERPINE2/LAMB2/HES1/ID4/GCM1/IL6/SHH/NOTCH1/SOX8/NOG/SOX9/MAG/C5AR1/BMP2/LIF | 17 |
| GOBP_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | GOBP_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | GOBP_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 17/1438 | 79/23056 | 0.2151899 | 3.450221 | 5.626345 | 0.0000059 | 0.0000677 | 0.0000435 | TGFB2/AGT/FN1/KDR/EGF/PDGFC/F2RL1/PDGFA/ANGPT1/TEK/IGF1/FLT3/FLT1/CCL5/CSF3/SOX9/PDGFB | 17 |
| GOBP_REGULATION_OF_ERBB_SIGNALING_PATHWAY | GOBP_REGULATION_OF_ERBB_SIGNALING_PATHWAY | GOBP_REGULATION_OF_ERBB_SIGNALING_PATHWAY | 17/1438 | 79/23056 | 0.2151899 | 3.450221 | 5.626345 | 0.0000059 | 0.0000677 | 0.0000435 | ERRFI1/AGT/TGFA/ZFYVE28/EPGN/EREG/BTC/EGF/HBEGF/SH3TC2/PTPN3/PTPRJ/GPRC5A/RHBDF1/CDH13/HAP1/RHBDF2 | 17 |
| GOMF_EXOGENOUS_PROTEIN_BINDING | GOMF_EXOGENOUS_PROTEIN_BINDING | GOMF_EXOGENOUS_PROTEIN_BINDING | 17/1438 | 79/23056 | 0.2151899 | 3.450221 | 5.626345 | 0.0000059 | 0.0000677 | 0.0000435 | TNFRSF4/EPHA2/ITGB6/DPP4/ITGB5/CLDN1/GYPA/ITGA2/MOG/ITGA5/SELPLG/ANPEP/CLDN6/CLEC4M/ICAM1/AXL/NECTIN2 | 17 |
| GOCC_SARCOLEMMA | GOCC_SARCOLEMMA | GOCC_SARCOLEMMA | 23/1438 | 131/23056 | 0.1755725 | 2.815021 | 5.373000 | 0.0000059 | 0.0000679 | 0.0000436 | SYNC/VCAM1/CASQ1/ATP2B4/DES/COL6A3/LAMA2/UTRN/AQP1/CAV2/CAV1/FLNC/ANXA1/VCL/AHNAK/AHNAK2/KRT19/SGCA/KCNJ2/SCN1B/CACNG6/COL6A2/BGN | 23 |
| WP_EBOLA_VIRUS_INFECTION_IN_HOST | WP_EBOLA_VIRUS_INFECTION_IN_HOST | WP_EBOLA_VIRUS_INFECTION_IN_HOST | 23/1438 | 131/23056 | 0.1755725 | 2.815021 | 5.373000 | 0.0000059 | 0.0000679 | 0.0000436 | RHOC/IKBKE/ITGA6/ITGA4/ITGA2/TFAP2A/HLA-E/HLA-C/SCIN/CAV2/CAV1/FLNC/DDX58/GSN/MBL2/NFKB2/ITGA5/MFGE8/ITGA3/SOCS3/CLEC4M/AXL/RELB | 23 |
| HOLLERN_EMT_BREAST_TUMOR_DN | HOLLERN_EMT_BREAST_TUMOR_DN | HOLLERN_EMT_BREAST_TUMOR_DN | 22/1438 | 122/23056 | 0.1803279 | 2.891265 | 5.401902 | 0.0000060 | 0.0000687 | 0.0000441 | ARHGEF16/CDCP1/CLDN1/DSP/DDR1/TMEM184A/NIPAL2/FZD6/EPPK1/CLIC3/EPS8L2/EHF/MPZL2/PLEKHG6/CLDN7/GRB7/KRT15/JUP/LLGL2/DSG2/TFAP2C/ZNF185 | 22 |
| HP_AORTIC_VALVE_STENOSIS | HP_AORTIC_VALVE_STENOSIS | HP_AORTIC_VALVE_STENOSIS | 14/1438 | 56/23056 | 0.2500000 | 4.008345 | 5.813156 | 0.0000062 | 0.0000703 | 0.0000452 | GJA1/DDX58/NOTCH1/WT1/ROBO4/VWF/LTBP2/FBN1/SMAD6/FOXF1/GATA6/SCN1B/CYP24A1/GATA5 | 14 |
| TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 37/1438 | 271/23056 | 0.1365314 | 2.189059 | 5.078294 | 0.0000062 | 0.0000703 | 0.0000452 | TNFRSF18/CDA/VCAM1/S100A13/MR1/TGFA/SP100/PLSCR4/ARAP2/GRAMD2B/SMIM3/CAP2/TENT5A/TMEM184A/PON3/MEST/CA13/COL5A1/ALOX5/HHEX/TSPAN32/PHLDA2/NRIP3/PTPRJ/APOA1/EPS8/NFE2/TMCC3/PYGL/PLEK2/PECAM1/SERPINB2/APOE/EMP3/CDC42EP5/RUNX1/ZNF185 | 37 |
| TSAI_RESPONSE_TO_IONIZING_RADIATION | TSAI_RESPONSE_TO_IONIZING_RADIATION | TSAI_RESPONSE_TO_IONIZING_RADIATION | 25/1438 | 150/23056 | 0.1666667 | 2.672230 | 5.299334 | 0.0000062 | 0.0000710 | 0.0000457 | PTPN22/DLX2/FN1/VEGFC/ITGA2/HBEGF/MDFI/TNFAIP3/AHR/PTN/MSC/KLF4/TRAF1/PLAU/FAS/NFKB2/BIRC3/CASP1/KRT8/IRF9/NFKBIA/KRT19/GDF15/AXL/IL2RB | 25 |
| GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 28/1438 | 179/23056 | 0.1564246 | 2.508015 | 5.223803 | 0.0000063 | 0.0000717 | 0.0000461 | GBP5/IFI16/MR1/IKBKE/NMI/WNT5A/TXK/EREG/DDX60/F2RL1/STING1/BMP6/HLA-E/SASH1/RAET1E/TRIM56/CD274/MBL2/TRIM5/KLRD1/KLRC4-KLRK1/OASL/NLRC5/CCL5/DHX58/IFI35/EMILIN2/NECTIN2 | 28 |
| GOBP_COLLAGEN_CATABOLIC_PROCESS | GOBP_COLLAGEN_CATABOLIC_PROCESS | GOBP_COLLAGEN_CATABOLIC_PROCESS | 12/1438 | 42/23056 | 0.2857143 | 4.580966 | 5.990775 | 0.0000063 | 0.0000721 | 0.0000464 | MMP23B/CTSS/FAP/ADAMTS3/ADAMTS2/MMP10/MMP1/MMP3/MMP14/MMP2/MRC2/KLK6 | 12 |
| HP_ABNORMAL_ATRIOVENTRICULAR_VALVE_MORPHOLOGY | HP_ABNORMAL_ATRIOVENTRICULAR_VALVE_MORPHOLOGY | HP_ABNORMAL_ATRIOVENTRICULAR_VALVE_MORPHOLOGY | 26/1438 | 160/23056 | 0.1625000 | 2.605424 | 5.255623 | 0.0000066 | 0.0000750 | 0.0000482 | TGFB2/COL3A1/COL5A2/TGFBR2/PLD1/SLC34A2/RREB1/TENT5A/GJA1/CITED2/TMEM270/TPM2/COL5A1/NOTCH1/MYPN/MYRF/VWF/MMP14/ACTC1/FBN1/HCN4/MMP2/FOXF1/COL1A1/GATA6/JPH2 | 26 |
| GOBP_NEUTROPHIL_CHEMOTAXIS | GOBP_NEUTROPHIL_CHEMOTAXIS | GOBP_NEUTROPHIL_CHEMOTAXIS | 20/1438 | 105/23056 | 0.1904762 | 3.053977 | 5.440561 | 0.0000067 | 0.0000759 | 0.0000488 | EDN2/TGFB2/IL1B/DPP4/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EDN1/CCL26/SAA1/C3AR1/NCKAP1L/CCL5/CCR7/C5AR1/RAC2 | 20 |
| COLDREN_GEFITINIB_RESISTANCE_DN | COLDREN_GEFITINIB_RESISTANCE_DN | COLDREN_GEFITINIB_RESISTANCE_DN | 33/1438 | 230/23056 | 0.1434783 | 2.300441 | 5.112038 | 0.0000067 | 0.0000759 | 0.0000488 | S100A16/LAMC2/ELF3/ITGB6/GALNT3/TMEM40/DOK7/ARAP2/RBM47/CDS1/NPNT/DDR1/CRYBG1/MACC1/ADAM28/LRATD2/EPPK1/ANKRD22/EPS8L2/PRRG4/EHF/RAB38/MPZL2/ARHGDIB/ALDH1A3/PITPNM3/CLDN7/KRT15/KRT19/B3GNT3/KLK6/SRPX2/TBC1D8B | 33 |
| GOBP_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 18/1438 | 88/23056 | 0.2045455 | 3.279555 | 5.525659 | 0.0000068 | 0.0000767 | 0.0000493 | COL3A1/HEG1/BCL6/F2RL1/MET/GPR20/NRP1/SYNPO2L/EPS8L2/ARHGAP42/APOC3/APOA1/ARHGDIB/EPS8/ITGA3/APOE/STARD8/LPAR4 | 18 |
| GOBP_ENDOCRINE_SYSTEM_DEVELOPMENT | GOBP_ENDOCRINE_SYSTEM_DEVELOPMENT | GOBP_ENDOCRINE_SYSTEM_DEVELOPMENT | 23/1438 | 132/23056 | 0.1742424 | 2.793695 | 5.330213 | 0.0000068 | 0.0000767 | 0.0000493 | WNT5A/HES1/PCSK1/BMP6/EDN1/CITED2/IL6/HOXA3/SHH/ANXA1/WT1/APOA1/GLI1/BMP4/SIX1/ALDH1A2/SALL1/HOXB3/GIP/NOG/SOX9/GATA6/BMP2 | 23 |
| GOBP_POSITIVE_REGULATION_OF_GLIOGENESIS | GOBP_POSITIVE_REGULATION_OF_GLIOGENESIS | GOBP_POSITIVE_REGULATION_OF_GLIOGENESIS | 15/1438 | 64/23056 | 0.2343750 | 3.757823 | 5.697998 | 0.0000068 | 0.0000775 | 0.0000498 | TNFRSF1B/IL1B/SERPINE2/HES1/IL6/PTPRZ1/PTN/SHH/PLAG1/NOTCH1/SOX8/MAG/TGFB1/BMP2/LIF | 15 |
| HP_ABNORMALLY_LAX_OR_HYPEREXTENSIBLE_SKIN | HP_ABNORMALLY_LAX_OR_HYPEREXTENSIBLE_SKIN | HP_ABNORMALLY_LAX_OR_HYPEREXTENSIBLE_SKIN | 27/1438 | 170/23056 | 0.1588235 | 2.546478 | 5.219603 | 0.0000069 | 0.0000775 | 0.0000498 | TBX15/TGFB2/COL3A1/COL5A2/TWIST2/CD96/FGFR3/OSMR/ADAMTS2/FOXC1/COL12A1/TENT5A/TMEM270/FGF20/TRPS1/EXT1/GSN/COL5A1/FGFR2/EFEMP2/C1S/C1R/SLC7A7/FBLN5/FBN1/COL1A1/RIN2 | 27 |
| GOBP_DEVELOPMENTAL_MATURATION | GOBP_DEVELOPMENTAL_MATURATION | GOBP_DEVELOPMENTAL_MATURATION | 39/1438 | 294/23056 | 0.1326531 | 2.126877 | 5.015326 | 0.0000070 | 0.0000794 | 0.0000511 | AGRN/S1PR1/TGFB2/PPARG/WNT5A/HES1/FGFR3/KDR/EREG/IL15/ADAMTS12/EDN1/TCP11/RUNX2/TDRD6/GJA1/FAM20C/EXT1/PAEP/RAB38/PGR/RND1/WNT10B/IGF1/EDNRB/NFATC4/SLC24A4/EPB42/GLDN/ALDH1A2/BNC1/SOX8/MMP2/HOXB13/C3/KLF2/AXL/BMP2/BFSP1 | 39 |
| RICKMAN_METASTASIS_DN | RICKMAN_METASTASIS_DN | RICKMAN_METASTASIS_DN | 36/1438 | 262/23056 | 0.1374046 | 2.203060 | 5.051052 | 0.0000071 | 0.0000800 | 0.0000514 | GBP1/GBP2/ADAMTSL4/S100A11/S100A2/S100A16/IFI16/PTGS2/ATP2B4/NUAK2/RAB7B/RASSF5/CAPG/CDCP1/PSMB9/PERP/DOK2/EPPK1/ANXA8/PRRG4/CD44/EHBP1L1/CASP1/MPZL2/AHNAK2/MYO1E/NLRC5/PITPNM3/KRT17/JUP/ITGB4/SLC16A3/TNFSF9/S1PR5/GAS2L1/A4GALT | 36 |
| GOBP_RESPONSE_TO_KETONE | GOBP_RESPONSE_TO_KETONE | GOBP_RESPONSE_TO_KETONE | 29/1438 | 190/23056 | 0.1526316 | 2.447200 | 5.166120 | 0.0000071 | 0.0000800 | 0.0000514 | ERRFI1/CDA/TGFB2/SRD5A2/CPS1/CLDN1/SLIT2/SPP1/EDN1/AHR/AQP1/CAV1/PLAT/FBXO32/ADCY8/AKR1C3/FIBIN/FOSL1/YAP1/POSTN/FOS/THBS1/NQO1/CCR7/HOXB13/MBP/KLF2/TGFB1/MSN | 29 |
| TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_DN | 16/1438 | 72/23056 | 0.2222222 | 3.562973 | 5.617612 | 0.0000071 | 0.0000803 | 0.0000516 | ELF3/ACTG2/IQCA1/MYLK/ID4/FAM126A/CAV1/PTN/ANXA1/SAA1/CRYAB/TAGLN/YBX3/FOS/KRT17/CNN1 | 16 |
| CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | 19/1438 | 97/23056 | 0.1958763 | 3.140559 | 5.448674 | 0.0000074 | 0.0000832 | 0.0000535 | COL6A3/BCL6/HES1/TGFBI/SPARC/IER3/LAMA4/GJA1/CCN2/THBS2/IL6/SULF1/TPM2/POSTN/NFKBIA/FOS/NUPR1/HSPB6/ITM2A | 19 |
| NAKAMURA_ADIPOGENESIS_LATE_UP | NAKAMURA_ADIPOGENESIS_LATE_UP | NAKAMURA_ADIPOGENESIS_LATE_UP | 19/1438 | 97/23056 | 0.1958763 | 3.140559 | 5.448674 | 0.0000074 | 0.0000832 | 0.0000535 | IL22RA1/TGFB2/NID1/CYBRD1/COL6A3/PPARG/P3H2/SMIM3/TNFRSF21/CD36/CEBPD/FABP4/S1PR3/ACSL5/FOXO1/IRF9/CDH13/ACSF2/TGFB1 | 19 |
| GOBP_REGULATION_OF_NEUROGENESIS | GOBP_REGULATION_OF_NEUROGENESIS | GOBP_REGULATION_OF_NEUROGENESIS | 45/1438 | 361/23056 | 0.1246537 | 1.998621 | 4.932230 | 0.0000076 | 0.0000850 | 0.0000547 | TNFRSF1B/CRABP2/IL1B/DLX1/DLX2/FN1/EPHA4/SERPINE2/BHLHE40/SEMA3B/WNT5A/MME/HES1/SLIT2/SPP1/VEGFC/SEMA5A/ID4/IL6/GLI3/SEMA3C/SEMA3A/SEMA3D/PTPRZ1/PTN/SHH/PLAG1/NOTCH1/NRP1/PITX3/YAP1/BHLHE41/NFATC4/SOX8/TRPV2/HAP1/HOXB3/NOG/MBP/SEMA6B/MAG/TGFB1/BMP2/TGM2/LIF | 45 |
| HP_JOINT_DISLOCATION | HP_JOINT_DISLOCATION | HP_JOINT_DISLOCATION | 44/1438 | 350/23056 | 0.1257143 | 2.015625 | 4.938002 | 0.0000077 | 0.0000860 | 0.0000553 | AGRN/HSPG2/TBX15/NLRP3/COL3A1/COL5A2/COL6A3/TGFBR2/WNT5A/CD96/FGFRL1/ADAMTS2/RREB1/COL12A1/TENT5A/GJA1/GLI3/TMEM270/SHH/CSGALNACT1/TRPS1/EXT1/TNFRSF11B/COLEC10/TPM2/GAS1/COL27A1/COL5A1/COL13A1/EFEMP2/ITGA7/ZIC2/SIX1/FBLN5/FBN1/SMAD6/MYH8/COL1A1/NOG/SOX9/PIEZO2/COL6A2/GPC4/BGN | 44 |
| GOBP_ICOSANOID_BIOSYNTHETIC_PROCESS | GOBP_ICOSANOID_BIOSYNTHETIC_PROCESS | GOBP_ICOSANOID_BIOSYNTHETIC_PROCESS | 14/1438 | 57/23056 | 0.2456140 | 3.938023 | 5.727860 | 0.0000077 | 0.0000865 | 0.0000556 | EDN2/PTGS2/PLA2G4A/IL1B/EDN1/ANXA1/PTGS1/AKR1C3/ALOX5/ALOX5AP/PTGIS/GGTLC3/GGTLC2/GGT1 | 14 |
| GOBP_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | GOBP_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | GOBP_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 23/1438 | 133/23056 | 0.1729323 | 2.772690 | 5.287825 | 0.0000077 | 0.0000865 | 0.0000556 | ZC3H12A/TGFB2/IL1A/IL1B/WNT5A/TLR3/F2RL1/SH3RF2/TPD52L1/CCN2/SASH1/SEMA3A/GDF6/TRAF1/IGFBP6/TNFRSF19/BMP4/CCR7/GADD45B/BMP2/BIRC7/WNT7B/MID1 | 23 |
| GOBP_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT | GOBP_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT | GOBP_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT | 9/1438 | 24/23056 | 0.3750000 | 6.012517 | 6.336507 | 0.0000077 | 0.0000866 | 0.0000557 | OSR1/COL3A1/MYLK/SHH/ITGA8/EFEMP2/BMP4/SIX1/SOX9 | 9 |
| SHI_SPARC_TARGETS_UP | SHI_SPARC_TARGETS_UP | SHI_SPARC_TARGETS_UP | 9/1438 | 24/23056 | 0.3750000 | 6.012517 | 6.336507 | 0.0000077 | 0.0000866 | 0.0000557 | TGFBR2/MME/AHRR/MZB1/SEMA3C/ARHGEF5/PPP1R3C/MMP1/GADD45B | 9 |
| HP_ABNORMAL_PHALANGEAL_JOINT_MORPHOLOGY_OF_THE_HAND | HP_ABNORMAL_PHALANGEAL_JOINT_MORPHOLOGY_OF_THE_HAND | HP_ABNORMAL_PHALANGEAL_JOINT_MORPHOLOGY_OF_THE_HAND | 30/1438 | 201/23056 | 0.1492537 | 2.393042 | 5.115944 | 0.0000078 | 0.0000877 | 0.0000564 | MMP23B/HSPG2/PTPN22/LAMC2/PRG4/LAMB3/NLRP3/ACTG2/COL6A3/TWIST2/TGFBR2/WNT5A/FGFR3/DOK7/ADAMTS3/FAT4/PSMB8/COL12A1/GJA1/SHH/TRPS1/TPM2/FGFR2/FBN1/MMP2/NOG/ITGB4/PIEZO2/COL6A2/GPC4 | 30 |
| HUANG_GATA2_TARGETS_UP | HUANG_GATA2_TARGETS_UP | HUANG_GATA2_TARGETS_UP | 25/1438 | 152/23056 | 0.1644737 | 2.637069 | 5.222607 | 0.0000079 | 0.0000886 | 0.0000570 | C1orf54/FCGR2A/TGFBR2/PLAC8/IQGAP2/HLA-E/PSMB8/PSMB9/AKR1B10/GSN/SRGN/HHEX/CD44/RAB38/TESPA1/GLIPR1/SELPLG/TPCN1/ALOX5AP/ANXA2/GMFG/KCNN4/EMP3/LGALS1/SAT1 | 25 |
| GOBP_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | GOBP_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | GOBP_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 35/1438 | 253/23056 | 0.1383399 | 2.218056 | 5.024420 | 0.0000081 | 0.0000907 | 0.0000583 | ZC3H12A/PTPN22/TGFB2/AGT/IL1A/IL1B/WNT5A/TLR3/F2RL1/SH3RF2/TPD52L1/CCN2/SASH1/SEMA3A/MDFIC/GDF6/TRAF1/FAS/CRYAB/IGFBP6/TNFRSF19/FOXO1/BMP4/DACT1/ZFP36L1/CCR7/GADD45B/ZFP36/CDC42EP5/SIRPA/BMP2/BIRC7/WNT7B/MID1/ARHGEF6 | 35 |
| BLANCO_MELO_MERS_COV_INFECTION_MCR5_CELLS_UP | BLANCO_MELO_MERS_COV_INFECTION_MCR5_CELLS_UP | BLANCO_MELO_MERS_COV_INFECTION_MCR5_CELLS_UP | 39/1438 | 296/23056 | 0.1317568 | 2.112506 | 4.968398 | 0.0000083 | 0.0000922 | 0.0000593 | ZC3H12A/PTCH2/CYP26B1/KCNE4/BHLHE40/XIRP1/MUC13/CPN2/TEC/TRIML2/HBEGF/SH3RF2/RNF144B/COL21A1/TENT5A/TNFAIP3/ZC3H12D/SLC22A1/HOXA1/COL26A1/ADAM32/EPPK1/MMRN2/ANKRD1/BAG3/MICAL2/PYGM/CRYAB/SLC6A13/STYK1/BHLHE41/KCNH3/PPM1H/NUAK1/NFKBIA/FOS/MYLK3/C5AR1/GABRE | 39 |
| BURTON_ADIPOGENESIS_7 | BURTON_ADIPOGENESIS_7 | BURTON_ADIPOGENESIS_7 | 13/1438 | 50/23056 | 0.2600000 | 4.168679 | 5.784914 | 0.0000083 | 0.0000922 | 0.0000593 | TINAGL1/VCAM1/VAMP5/SERPINE2/PLAC8/TGFBI/S1PR3/PTGS1/IFITM3/CD44/HMGA2/FBN1/NQO1 | 13 |
| GOBP_LUNG_MORPHOGENESIS | GOBP_LUNG_MORPHOGENESIS | GOBP_LUNG_MORPHOGENESIS | 13/1438 | 50/23056 | 0.2600000 | 4.168679 | 5.784914 | 0.0000083 | 0.0000922 | 0.0000593 | TGFBR2/SHH/RSPO2/EXT1/FGFR2/YAP1/BMP4/FOXF1/NOG/SOX9/LIF/WNT7B/CELSR1 | 13 |
| AMIT_EGF_RESPONSE_480_MCF10A | AMIT_EGF_RESPONSE_480_MCF10A | AMIT_EGF_RESPONSE_480_MCF10A | 12/1438 | 43/23056 | 0.2790698 | 4.474431 | 5.881466 | 0.0000083 | 0.0000923 | 0.0000593 | SH2D2A/VEGFC/ITGA2/FST/FOXD1/STC1/PHLDA2/NAV3/PLEK2/BDKRB1/SOX9/LYPD3 | 12 |
| GOBP_MAMMARY_GLAND_MORPHOGENESIS | GOBP_MAMMARY_GLAND_MORPHOGENESIS | GOBP_MAMMARY_GLAND_MORPHOGENESIS | 12/1438 | 43/23056 | 0.2790698 | 4.474431 | 5.881466 | 0.0000083 | 0.0000923 | 0.0000593 | EPHA2/CSF1/ELF3/TGFBR2/WNT5A/DDR1/GLI3/CAV1/FGFR2/PGR/STAT6/BMP4 | 12 |
| GOBP_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY | GOBP_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY | GOBP_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY | 12/1438 | 43/23056 | 0.2790698 | 4.474431 | 5.881466 | 0.0000083 | 0.0000923 | 0.0000593 | ECE1/NRP2/SEMA3B/SEMA5A/GDNF/EDN1/SEMA3C/SEMA3A/SEMA3D/MET/NRP1/SEMA6B | 12 |
| GOBP_HEART_VALVE_DEVELOPMENT | GOBP_HEART_VALVE_DEVELOPMENT | GOBP_HEART_VALVE_DEVELOPMENT | 15/1438 | 65/23056 | 0.2307692 | 3.700011 | 5.622086 | 0.0000084 | 0.0000931 | 0.0000599 | TNFRSF1B/TIE1/CCN1/TGFB2/TGFBR2/FGFRL1/SLIT2/NOTCH1/TNFRSF1A/BMP4/SMAD6/SOX9/TGFB1/BMP2/GATA5 | 15 |
| GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 24/1438 | 143/23056 | 0.1678322 | 2.690917 | 5.231227 | 0.0000084 | 0.0000931 | 0.0000599 | ERRFI1/CCN1/TM4SF1/CXCL2/PLK2/HBEGF/EDN1/CCN2/TCIM/KLF4/SRGN/ANKRD1/CD44/GPRC5A/RND1/PHLDA1/NFKBIA/FRMD6/FOS/ANXA2/ZFP36/SDC4/SAT1/IL13RA1 | 24 |
| BIOCARTA_LYM_PATHWAY | BIOCARTA_LYM_PATHWAY | BIOCARTA_LYM_PATHWAY | 7/1438 | 14/23056 | 0.5000000 | 8.016690 | 6.773146 | 0.0000084 | 0.0000932 | 0.0000599 | VCAM1/CD34/IL1A/ITGA4/CXCL8/PECAM1/ICAM1 | 7 |
| BLANCO_MELO_COVID19_SARS_COV_2_LOW_MOI_INFECTION_A594_ACE2_EXPRESSING_CELLS_DN | BLANCO_MELO_COVID19_SARS_COV_2_LOW_MOI_INFECTION_A594_ACE2_EXPRESSING_CELLS_DN | BLANCO_MELO_COVID19_SARS_COV_2_LOW_MOI_INFECTION_A594_ACE2_EXPRESSING_CELLS_DN | 7/1438 | 14/23056 | 0.5000000 | 8.016690 | 6.773146 | 0.0000084 | 0.0000932 | 0.0000599 | DPP4/CPA4/KRT4/CPM/KRT15/KRT19/PSG5 | 7 |
| LY_AGING_MIDDLE_UP | LY_AGING_MIDDLE_UP | LY_AGING_MIDDLE_UP | 7/1438 | 14/23056 | 0.5000000 | 8.016690 | 6.773146 | 0.0000084 | 0.0000932 | 0.0000599 | CXCL8/THBS2/TNFRSF11B/PTGS1/HTRA1/MMP10/SERPINB2 | 7 |
| GOCC_ADHERENS_JUNCTION | GOCC_ADHERENS_JUNCTION | GOCC_ADHERENS_JUNCTION | 27/1438 | 172/23056 | 0.1569767 | 2.516868 | 5.149917 | 0.0000086 | 0.0000947 | 0.0000609 | NEXN/S100A11/HMCN1/CCDC85A/MPP4/EPHA4/ARHGAP24/CDH9/PTPRK/ZYX/PDLIM2/ANXA1/NOTCH1/JCAD/VCL/RND1/KRT18/AJUBA/MYO1E/ANXA2/KIFC3/JUP/WTIP/NECTIN2/MYH9/CDC42EP1/MSN | 27 |
| FURUKAWA_DUSP6_TARGETS_PCI35_UP | FURUKAWA_DUSP6_TARGETS_PCI35_UP | FURUKAWA_DUSP6_TARGETS_PCI35_UP | 16/1438 | 73/23056 | 0.2191781 | 3.514165 | 5.548891 | 0.0000086 | 0.0000950 | 0.0000611 | TMCO4/TGFB2/TNNC1/RTP4/CLDN16/PSMB9/AQP3/AKR1C3/SAA1/SLC15A3/PLAAT4/C1S/TNFSF13B/IL32/KRT17/HMOX1 | 16 |
| GOBP_CARDIAC_VENTRICLE_MORPHOGENESIS | GOBP_CARDIAC_VENTRICLE_MORPHOGENESIS | GOBP_CARDIAC_VENTRICLE_MORPHOGENESIS | 16/1438 | 73/23056 | 0.2191781 | 3.514165 | 5.548891 | 0.0000086 | 0.0000950 | 0.0000611 | TGFB2/BMP10/TGFBR2/TNNC1/HEG1/FOXC1/DSP/SEMA3C/ZFPM2/NOTCH1/FGFR2/BMP4/TPM1/FOXF1/NOG/TGFB1 | 16 |
| GOBP_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | GOBP_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | GOBP_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | 19/1438 | 98/23056 | 0.1938776 | 3.108512 | 5.394813 | 0.0000086 | 0.0000952 | 0.0000612 | S100A10/ITGA6/FN1/EPHA3/PHLDB2/KDR/ITGA2/PTPRK/TRIP6/TEK/NRP1/VCL/PTPRJ/ITGA5/MMP14/AJUBA/THBS1/ITGB4/SDC4 | 19 |
| GOBP_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | 19/1438 | 98/23056 | 0.1938776 | 3.108512 | 5.394813 | 0.0000086 | 0.0000952 | 0.0000612 | ITGA4/KDR/SEMA5A/TNFAIP3/IL6/SERPINE1/ANGPT1/TEK/GSN/AKR1C3/TCF7L2/YAP1/ZFP36L1/THBS1/NUPR1/ICAM1/ZFP36/IL11/HMOX1 | 19 |
| WP_SMALL_CELL_LUNG_CANCER | WP_SMALL_CELL_LUNG_CANCER | WP_SMALL_CELL_LUNG_CANCER | 19/1438 | 98/23056 | 0.1938776 | 3.108512 | 5.394813 | 0.0000086 | 0.0000952 | 0.0000612 | LAMC2/PTGS2/LAMB3/ITGA6/CASP8/FN1/RARB/LAMB2/ITGA2/LAMA4/LAMA2/TRAF1/BIRC3/NFKBIA/ITGA3/GADD45B/BIRC7/COL4A6/COL4A5 | 19 |
| GOBP_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS | GOBP_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS | GOBP_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS | 23/1438 | 134/23056 | 0.1716418 | 2.751998 | 5.245827 | 0.0000088 | 0.0000965 | 0.0000621 | LTBP1/DLX1/PPARG/VEPH1/NPNT/DAB2/CD109/CITED2/CAV2/CAV1/ZNF703/HTRA4/ITGA8/HTRA1/BCL9L/LATS2/THBS1/FBN1/SMAD6/MYOCD/ITGA3/TGFB1/BMP2 | 23 |
| GOBP_ANATOMICAL_STRUCTURE_HOMEOSTASIS | GOBP_ANATOMICAL_STRUCTURE_HOMEOSTASIS | GOBP_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 41/1438 | 319/23056 | 0.1285266 | 2.060716 | 4.920195 | 0.0000090 | 0.0000994 | 0.0000639 | RPE65/S1PR1/CSF1/ILDR2/PTGS2/CD34/ITGB6/COL3A1/MUC13/WWTR1/CLDN1/KDR/JCHAIN/SPP1/ADRB2/FOXC1/ADGRF5/GJA1/LAMA2/CCN2/TNFAIP3/IL6/PDK4/ANGPT1/EXT1/TNFRSF11B/NXNL2/CRB2/NOTCH1/VCL/SFTPD/BAG3/ARMS2/YAP1/UBASH3B/ESRRB/PECAM1/SOX9/SIGLEC15/TNFRSF11A/MBP | 41 |
| ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | 21/1438 | 116/23056 | 0.1810345 | 2.902595 | 5.298254 | 0.0000091 | 0.0000999 | 0.0000642 | RHOC/ADAMTSL4/S100A11/PTPRC/KYNU/ARHGEF5/AQP3/TOR4A/C11orf21/SLCO2B1/SERPINH1/KRT8/KRT18/NFE2/TESPA1/LRP10/ACSM3/TRPV2/BCAM/RAC2/GABRE | 21 |
| GOBP_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION | 8/1438 | 19/23056 | 0.4210526 | 6.750897 | 6.467756 | 0.0000091 | 0.0000999 | 0.0000642 | SERPINE2/PDGFA/UBASH3B/ADAMTS18/C1QTNF1/APOE/THBD/PDGFB | 8 |
| GOBP_NEPHRON_TUBULE_FORMATION | GOBP_NEPHRON_TUBULE_FORMATION | GOBP_NEPHRON_TUBULE_FORMATION | 8/1438 | 19/23056 | 0.4210526 | 6.750897 | 6.467756 | 0.0000091 | 0.0000999 | 0.0000642 | OSR1/IRX2/GDNF/SIX1/SIX4/SOX8/NOG/SOX9 | 8 |
| GOBP_RENAL_VESICLE_DEVELOPMENT | GOBP_RENAL_VESICLE_DEVELOPMENT | GOBP_RENAL_VESICLE_DEVELOPMENT | 8/1438 | 19/23056 | 0.4210526 | 6.750897 | 6.467756 | 0.0000091 | 0.0000999 | 0.0000642 | OSR1/GDNF/BMP4/SOX8/SALL1/LHX1/SOX9/LIF | 8 |
| GOMF_POLYPEPTIDE_N_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | GOMF_POLYPEPTIDE_N_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | GOMF_POLYPEPTIDE_N_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | 8/1438 | 19/23056 | 0.4210526 | 6.750897 | 6.467756 | 0.0000091 | 0.0000999 | 0.0000642 | GALNT5/GALNT3/GALNT15/GALNTL6/GALNT10/GALNT17/GALNT18/GALNT9 | 8 |
| STREICHER_LSM1_TARGETS_DN | STREICHER_LSM1_TARGETS_DN | STREICHER_LSM1_TARGETS_DN | 8/1438 | 19/23056 | 0.4210526 | 6.750897 | 6.467756 | 0.0000091 | 0.0000999 | 0.0000642 | ITGB6/IL1RAP/FST/IL6/TNFRSF10A/IL15RA/FZD8/TGFB1 | 8 |
| GOBP_CARDIAC_MUSCLE_CELL_PROLIFERATION | GOBP_CARDIAC_MUSCLE_CELL_PROLIFERATION | GOBP_CARDIAC_MUSCLE_CELL_PROLIFERATION | 14/1438 | 58/23056 | 0.2413793 | 3.870126 | 5.644483 | 0.0000096 | 0.0001046 | 0.0000672 | TGFB2/BMP10/TGFBR2/FOXC1/CITED2/FGF20/ZFPM2/NOTCH1/FGFR2/YAP1/GLI1/NOG/GATA6/RUNX1 | 14 |
| GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 14/1438 | 58/23056 | 0.2413793 | 3.870126 | 5.644483 | 0.0000096 | 0.0001046 | 0.0000672 | IL1B/KDR/VEGFC/FGF18/FOXC1/SULF1/NRP1/MMRN2/HHEX/FZD4/ITGA5/FLT1/PRKD1/AXL | 14 |
| PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | 14/1438 | 58/23056 | 0.2413793 | 3.870126 | 5.644483 | 0.0000096 | 0.0001046 | 0.0000672 | VCAM1/CSF1/EPHA4/PLSCR2/IL1RAP/PERP/ADGRG6/SEMA3C/PDK4/PCSK5/AIF1L/FAS/MPZL2/C1S | 14 |
| HP_FLEXION_CONTRACTURE_OF_DIGIT | HP_FLEXION_CONTRACTURE_OF_DIGIT | HP_FLEXION_CONTRACTURE_OF_DIGIT | 40/1438 | 309/23056 | 0.1294498 | 2.075518 | 4.908957 | 0.0000097 | 0.0001064 | 0.0000684 | MMP23B/ECE1/HSPG2/TBX15/LAMC2/PRG4/LAMB3/NLRP3/ACTG2/COL3A1/COL6A3/TWIST2/TGFBR2/WNT5A/FGFR3/DOK7/ADAMTS3/FAT4/DSP/PSMB8/COL12A1/GJA1/PERP/GLI3/SHH/TRPS1/TPM2/FGFR2/ITGA7/BMP4/FBN1/MMP2/MAF/JUP/NOG/ITGB4/PIEZO2/COL6A2/GPC4/BGN | 40 |
| GOBP_PHARYNGEAL_ARCH_ARTERY_MORPHOGENESIS | GOBP_PHARYNGEAL_ARCH_ARTERY_MORPHOGENESIS | GOBP_PHARYNGEAL_ARCH_ARTERY_MORPHOGENESIS | 6/1438 | 10/23056 | 0.6000000 | 9.620028 | 7.031778 | 0.0000098 | 0.0001070 | 0.0000688 | TGFB2/HES1/EDN1/ADGRF5/BMP4/NOG | 6 |
| GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_CONSTITUENT_SECRETION | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_CONSTITUENT_SECRETION | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_CONSTITUENT_SECRETION | 6/1438 | 10/23056 | 0.6000000 | 9.620028 | 7.031778 | 0.0000098 | 0.0001070 | 0.0000688 | TNFRSF1B/AGT/ADTRP/NOTCH1/TNFRSF1A/BMP2 | 6 |
| HP_ABNORMAL_DERMOEPIDERMAL_JUNCTION_MORPHOLOGY | HP_ABNORMAL_DERMOEPIDERMAL_JUNCTION_MORPHOLOGY | HP_ABNORMAL_DERMOEPIDERMAL_JUNCTION_MORPHOLOGY | 6/1438 | 10/23056 | 0.6000000 | 9.620028 | 7.031778 | 0.0000098 | 0.0001070 | 0.0000688 | LAMC2/LAMB3/ITGA6/DSP/JUP/ITGB4 | 6 |
| HP_SUBRETINAL_FLUID | HP_SUBRETINAL_FLUID | HP_SUBRETINAL_FLUID | 6/1438 | 10/23056 | 0.6000000 | 9.620028 | 7.031778 | 0.0000098 | 0.0001070 | 0.0000688 | CFH/EFEMP1/CFI/TSPAN12/FZD4/NDP | 6 |
| HOSHIDA_LIVER_CANCER_SUBCLASS_S3 | HOSHIDA_LIVER_CANCER_SUBCLASS_S3 | HOSHIDA_LIVER_CANCER_SUBCLASS_S3 | 36/1438 | 266/23056 | 0.1353383 | 2.169931 | 4.949749 | 0.0000100 | 0.0001084 | 0.0000697 | TINAGL1/CFH/CPS1/ITIH3/MYLK/SLCO2A1/MME/CXCL2/TDO2/CTSO/IQGAP2/SOD2/PON3/PDK4/CPA4/RARRES2/AQP7/PTGR1/PAPSS2/NNMT/APOA1/C1S/C1R/IGF1/HPD/FOXO1/EDNRB/NFKBIA/SERPINA6/MYO1E/IL32/CES1/MT2A/BLVRB/COL18A1/IL13RA1 | 36 |
| KUNINGER_IGF1_VS_PDGFB_TARGETS_UP | KUNINGER_IGF1_VS_PDGFB_TARGETS_UP | KUNINGER_IGF1_VS_PDGFB_TARGETS_UP | 17/1438 | 82/23056 | 0.2073171 | 3.323993 | 5.437231 | 0.0000100 | 0.0001089 | 0.0000700 | HJV/ATP2B4/CAVIN2/XIRP1/TNNC1/NPNT/FST/LMOD2/TPM2/SYNPO2L/PYGM/ACTC1/TPM1/SOX8/MYL4/SGCA/SMPX | 17 |
| DAZARD_RESPONSE_TO_UV_NHEK_UP | DAZARD_RESPONSE_TO_UV_NHEK_UP | DAZARD_RESPONSE_TO_UV_NHEK_UP | 32/1438 | 224/23056 | 0.1428571 | 2.290483 | 5.005627 | 0.0000100 | 0.0001090 | 0.0000701 | CCN1/PTGS2/KYNU/DLX2/TM4SF1/CXCL8/CXCL1/CXCL3/CXCL2/HBEGF/FOXC1/IER3/RCAN2/COL19A1/LAMA2/CCN2/TNFAIP3/CITED2/IL6/PHLDA2/ADM/MMP10/TAGLN/IGFBP6/STAT6/PHLDA1/FOS/ANXA2/GADD45B/ZFP36/TGFB1/APOE | 32 |
| HP_RETINAL_DETACHMENT | HP_RETINAL_DETACHMENT | HP_RETINAL_DETACHMENT | 19/1438 | 99/23056 | 0.1919192 | 3.077113 | 5.341638 | 0.0000101 | 0.0001092 | 0.0000702 | RPE65/PTPN22/ADAMTSL4/CFH/EFEMP1/P3H2/CFI/TSPAN12/TEK/FAS/FZD4/YAP1/LTBP2/FBN1/ALDH1A3/MAF/COL9A3/COL18A1/NDP | 19 |
| HP_ABNORMALITY_OF_CARDIOVASCULAR_SYSTEM_ELECTROPHYSIOLOGY | HP_ABNORMALITY_OF_CARDIOVASCULAR_SYSTEM_ELECTROPHYSIOLOGY | HP_ABNORMALITY_OF_CARDIOVASCULAR_SYSTEM_ELECTROPHYSIOLOGY | 56/1438 | 492/23056 | 0.1138211 | 1.824938 | 4.770345 | 0.0000101 | 0.0001093 | 0.0000702 | ECE1/HSPG2/LDLRAP1/NEXN/PTPN22/HJV/FMO3/LAMC2/LAMB3/KYNU/DES/TGFBR2/TNNC1/TECRL/MYOZ2/DSP/HFE/PSMB8/RHAG/GJA1/TRDN/LAMA2/CITED2/TMEM270/SEMA3A/FLNC/SHH/TPM2/GAS1/GSN/MYPN/PYGM/EFEMP2/KCNA5/SCNN1A/ZIC2/MMP14/ACTC1/TPM1/HCN4/ALPK3/MMP2/JUP/CAVIN1/MYL4/KCNJ2/GATA6/DSG2/CACNA1A/SCN1B/RRAS/BMP2/JPH2/GATA5/USP18/GPC4 | 56 |
| HP_BIFID_SCROTUM | HP_BIFID_SCROTUM | HP_BIFID_SCROTUM | 11/1438 | 37/23056 | 0.2972973 | 4.766680 | 5.913855 | 0.0000101 | 0.0001094 | 0.0000704 | SRD5A2/FAT4/PLAG1/COLEC10/FGFR2/MYRF/HMGA2/BMP4/DACT1/SALL1/SOX9 | 11 |
| HP_ABNORMAL_BLEEDING | HP_ABNORMAL_BLEEDING | HP_ABNORMAL_BLEEDING | 54/1438 | 469/23056 | 0.1151386 | 1.846061 | 4.774336 | 0.0000104 | 0.0001125 | 0.0000723 | PTPN22/HMCN1/CFH/TGFB2/NLRP3/EFEMP1/COL3A1/COL5A2/NABP1/CASP10/FN1/SP110/TGFBR2/MYLK/SLCO2A1/CFI/ITGA2/SPARC/ADAMTS2/RREB1/CD109/TENT5A/STX11/CD36/SAMD9/EPHB4/SERPINE1/TSPAN12/TEK/GSN/COL5A1/NOTCH1/PLAU/FAS/NFKB2/FZD4/VWF/TNFRSF1A/C1S/C1R/SLC7A7/FBN1/COL1A1/ITGB4/RHBDF2/PLVAP/APOE/RRAS/RIN2/RUNX1/USP18/MYH9/PDGFB/NDP | 54 |
| HP_ABNORMAL_HEART_VALVE_PHYSIOLOGY | HP_ABNORMAL_HEART_VALVE_PHYSIOLOGY | HP_ABNORMAL_HEART_VALVE_PHYSIOLOGY | 42/1438 | 332/23056 | 0.1265060 | 2.028319 | 4.867532 | 0.0000105 | 0.0001130 | 0.0000727 | LDLRAP1/TGFB2/COL5A2/TGFBR2/MYLK/PLD1/FAT4/DSP/TENT5A/GJA1/CITED2/TMEM270/FLNC/CSGALNACT1/DDX58/COL5A1/NOTCH1/MYPN/FAS/WT1/EFEMP2/CRYAB/ROBO4/VWF/LTBP2/FBLN5/ACTC1/FBN1/TPM1/SMAD6/HCN4/ALPK3/FOXF1/RNF135/COL1A1/GATA6/SCN1B/BMP2/CYP24A1/GATA5/GPC4/BGN | 42 |
| FRASOR_TAMOXIFEN_RESPONSE_UP | FRASOR_TAMOXIFEN_RESPONSE_UP | FRASOR_TAMOXIFEN_RESPONSE_UP | 13/1438 | 51/23056 | 0.2549020 | 4.086940 | 5.691889 | 0.0000105 | 0.0001130 | 0.0000727 | NIBAN1/ELF3/LTBP1/BHLHE40/DAB2/IER3/CLIC3/CD44/CPM/SERPINA1/KRT13/IL13RA1/ZNF185 | 13 |
| GOBP_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | GOBP_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | GOBP_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | 13/1438 | 51/23056 | 0.2549020 | 4.086940 | 5.691889 | 0.0000105 | 0.0001130 | 0.0000727 | CSF1/DPP4/SLIT2/CXCL8/EDN1/RARRES2/C3AR1/NCKAP1L/THBS1/CCL5/CCR7/C5AR1/RAC2 | 13 |
| GOBP_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | GOBP_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | GOBP_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 30/1438 | 204/23056 | 0.1470588 | 2.357850 | 5.024108 | 0.0000106 | 0.0001140 | 0.0000733 | IL1A/SOD3/EDN1/PTPRK/TNFAIP3/SOD2/IL6/AQP1/CD36/MET/GPR37/ADAM9/TRPA1/ANXA1/AKR1C3/FOSL1/CRYAB/KCNA5/STAT6/FOS/FBLN5/TPM1/MMP2/NQO1/COL1A1/KLF2/AXL/APOE/SIRPA/HMOX1 | 30 |
| PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | 32/1438 | 225/23056 | 0.1422222 | 2.280303 | 4.977322 | 0.0000110 | 0.0001188 | 0.0000764 | AGRN/CCN1/PTGS2/IKBKE/SERPINE2/WNT5A/MYO10/IL7R/FOXC1/PTPRK/CAV1/CSGALNACT1/FABP4/EXT1/TNFRSF11B/B4GALT1/NOTCH1/ZCCHC24/HHEX/CD82/ITGA5/GLIPR1/NAV3/PRKD1/FOS/DIO2/MBP/ZFP36/BCL3/IL11/CDC42EP1/MID1 | 32 |
| GOBP_ROOF_OF_MOUTH_DEVELOPMENT | GOBP_ROOF_OF_MOUTH_DEVELOPMENT | GOBP_ROOF_OF_MOUTH_DEVELOPMENT | 18/1438 | 91/23056 | 0.1978022 | 3.171438 | 5.352900 | 0.0000111 | 0.0001191 | 0.0000765 | DHRS3/PRRX1/TGFB2/OSR1/ITGB6/TGFBR2/WNT5A/LEF1/TFAP2A/ITGB8/INHBA/GLI3/FZD1/SHH/ASPH/MSC/ALX4/LRRC32 | 18 |
| WP_SELENIUM_MICRONUTRIENT_NETWORK | WP_SELENIUM_MICRONUTRIENT_NETWORK | WP_SELENIUM_MICRONUTRIENT_NETWORK | 18/1438 | 91/23056 | 0.1978022 | 3.171438 | 5.352900 | 0.0000111 | 0.0001191 | 0.0000765 | PTGS2/IL1B/KYNU/SOD3/SOD2/IL6/SERPINE1/PLAT/PTGS1/ALOX5/NFKB2/SAA1/APOA1/ALOX5AP/DIO2/ICAM1/GGTLC2/GGT1 | 18 |
| HP_ABNORMAL_SCAPULA_MORPHOLOGY | HP_ABNORMAL_SCAPULA_MORPHOLOGY | HP_ABNORMAL_SCAPULA_MORPHOLOGY | 25/1438 | 155/23056 | 0.1612903 | 2.586029 | 5.109801 | 0.0000113 | 0.0001211 | 0.0000778 | HSPG2/PTCH2/TBX15/COL3A1/COL6A3/LAMB2/FGFR3/SH3TC2/PSMB8/RUNX2/COL12A1/CSGALNACT1/GDF6/RSPO2/TRPS1/EXT1/TPM2/MYPN/FBN1/MYH2/MEOX1/SGCA/KCNJ2/SOX9/COL6A2 | 25 |
| GOBP_EPITHELIAL_TUBE_FORMATION | GOBP_EPITHELIAL_TUBE_FORMATION | GOBP_EPITHELIAL_TUBE_FORMATION | 23/1438 | 136/23056 | 0.1691176 | 2.711527 | 5.162978 | 0.0000113 | 0.0001212 | 0.0000779 | TGFB2/OSR1/WNT5A/EGF/IRX2/GDNF/CITED2/FZD1/PODXL/FZD6/CTHRC1/MMRN2/FGFR2/ADM/BMP4/SIX1/SIX4/SOX8/NOG/SOX9/TGFB1/SDC4/CELSR1 | 23 |
| GOBP_METANEPHRIC_NEPHRON_MORPHOGENESIS | GOBP_METANEPHRIC_NEPHRON_MORPHOGENESIS | GOBP_METANEPHRIC_NEPHRON_MORPHOGENESIS | 9/1438 | 25/23056 | 0.3600000 | 5.772017 | 6.157009 | 0.0000114 | 0.0001221 | 0.0000785 | HES1/GDNF/WT1/BMP4/SOX8/SALL1/LHX1/SOX9/LIF | 9 |
| REACTOME_BASIGIN_INTERACTIONS | REACTOME_BASIGIN_INTERACTIONS | REACTOME_BASIGIN_INTERACTIONS | 9/1438 | 25/23056 | 0.3600000 | 5.772017 | 6.157009 | 0.0000114 | 0.0001221 | 0.0000785 | ITGA6/SLC7A11/CAV1/MMP1/SLC7A7/ITGA3/SLC16A3/SLC7A10/MAG | 9 |
| GOBP_BONE_GROWTH | GOBP_BONE_GROWTH | GOBP_BONE_GROWTH | 10/1438 | 31/23056 | 0.3225806 | 5.172058 | 5.994951 | 0.0000114 | 0.0001221 | 0.0000785 | ECM1/RARB/TGFBR2/OSTN/FGFR3/STC1/EXT1/COL27A1/FGFR2/SOX9 | 10 |
| GOBP_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | 10/1438 | 31/23056 | 0.3225806 | 5.172058 | 5.994951 | 0.0000114 | 0.0001221 | 0.0000785 | EPHA4/SERPINE2/HES1/ID4/IL6/NOTCH1/NOG/MAG/BMP2/LIF | 10 |
| SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | 10/1438 | 31/23056 | 0.3225806 | 5.172058 | 5.994951 | 0.0000114 | 0.0001221 | 0.0000785 | ITGA6/FN1/EREG/ITGA2/PTP4A1/SEMA3C/AHNAK/EMP1/THBS1/THBD | 10 |
| URS_ADIPOCYTE_DIFFERENTIATION_DN | URS_ADIPOCYTE_DIFFERENTIATION_DN | URS_ADIPOCYTE_DIFFERENTIATION_DN | 10/1438 | 31/23056 | 0.3225806 | 5.172058 | 5.994951 | 0.0000114 | 0.0001221 | 0.0000785 | COL3A1/FN1/COL6A3/SPARC/THBS2/LUM/LOXL1/OSGIN1/PSG9/CD37 | 10 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 29/1438 | 195/23056 | 0.1487179 | 2.384451 | 5.007277 | 0.0000118 | 0.0001263 | 0.0000812 | TRABD2B/GBP5/RHOC/LMOD1/TRABD2A/CAPG/CSF2/CCL26/CD36/MET/LMOD2/ARHGEF5/CLU/MMP1/MMP3/WNT10B/NCKAP1L/NAV3/LCP1/AJUBA/BMF/PIEZO1/CSF3/CCR7/TGFB1/CDC42EP5/CDC42EP1/MSN/TENM1 | 29 |
| MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | MORI_LARGE_PRE_BII_LYMPHOCYTE_DN | 14/1438 | 59/23056 | 0.2372881 | 3.804531 | 5.562946 | 0.0000118 | 0.0001263 | 0.0000812 | VCAM1/CTSS/PTPRC/CAPG/UBA7/LPP/DOCK2/SERPINB1/CRYBG1/BIRC3/LCP1/IL4R/CD22/IL4I1 | 14 |
| ZHENG_IL22_SIGNALING_UP | ZHENG_IL22_SIGNALING_UP | ZHENG_IL22_SIGNALING_UP | 14/1438 | 59/23056 | 0.2372881 | 3.804531 | 5.562946 | 0.0000118 | 0.0001263 | 0.0000812 | ALDH1L1/CLDN1/CXCL6/CXCL1/STING1/INHBA/FZD1/PLAT/HBD/SLFN13/CCL5/C3/THBD/CELSR1 | 14 |
| HP_ABNORMALITY_OF_THE_WRIST | HP_ABNORMALITY_OF_THE_WRIST | HP_ABNORMALITY_OF_THE_WRIST | 24/1438 | 146/23056 | 0.1643836 | 2.635624 | 5.113304 | 0.0000121 | 0.0001286 | 0.0000827 | HSPG2/PTPN22/TBX15/PRG4/COL6A3/COL7A1/LAMB2/FGFR3/SLC34A2/COL12A1/GJA1/SHH/EXT1/TPM2/FGFR2/GLI1/MMP14/MMP2/NOG/PIEZO2/COL6A2/IL2RB/GPC4/BGN | 24 |
| HP_ATRIAL_ARRHYTHMIA | HP_ATRIAL_ARRHYTHMIA | HP_ATRIAL_ARRHYTHMIA | 16/1438 | 75/23056 | 0.2133333 | 3.420454 | 5.414986 | 0.0000124 | 0.0001320 | 0.0000849 | NEXN/TNNC1/MYOZ2/TRDN/CITED2/FLNC/MYPN/KCNA5/ACTC1/HCN4/CAVIN1/MYL4/KCNJ2/GATA6/SCN1B/GATA5 | 16 |
| HP_ABNORMALITY_OF_THE_ABDOMINAL_WALL | HP_ABNORMALITY_OF_THE_ABDOMINAL_WALL | HP_ABNORMALITY_OF_THE_ABDOMINAL_WALL | 55/1438 | 484/23056 | 0.1136364 | 1.821975 | 4.713576 | 0.0000126 | 0.0001345 | 0.0000865 | HSPG2/FUCA1/LMOD1/TGFB2/NLRP3/ACTG2/COL3A1/COL5A2/TWIST2/TGFBR2/WNT5A/CD96/MYLK/PLD1/SEMA5A/ADAMTS2/RREB1/TENT5A/GJA1/BMPER/GLI3/TMEM270/SHH/PLAG1/COLEC10/GLIS3/COL5A1/NOTCH1/FGFR2/EFEMP2/SERPINH1/C1S/C1R/HMGA2/GRIP1/FREM2/ZIC2/MMP14/DACT1/FBLN5/FBN1/SALL1/MMP2/LDHD/MAF/FOXF1/PIEZO1/CAVIN1/COL1A1/PIEZO2/GATA6/SCN1B/RRAS/RIN2/GPC4 | 55 |
| GAVIN_FOXP3_TARGETS_CLUSTER_P7 | GAVIN_FOXP3_TARGETS_CLUSTER_P7 | GAVIN_FOXP3_TARGETS_CLUSTER_P7 | 18/1438 | 92/23056 | 0.1956522 | 3.136966 | 5.296902 | 0.0000130 | 0.0001378 | 0.0000886 | GBP2/ECM1/PRG4/TMEM158/ADAMTS6/PPIC/GRAMD2B/NT5E/ANXA1/C9orf152/IFITM3/KLRD1/EMP1/AMIGO2/FOS/MYO1E/KCNK6/PRNP | 18 |
| GOBP_HOMOTYPIC_CELL_CELL_ADHESION | GOBP_HOMOTYPIC_CELL_CELL_ADHESION | GOBP_HOMOTYPIC_CELL_CELL_ADHESION | 18/1438 | 92/23056 | 0.1956522 | 3.136966 | 5.296902 | 0.0000130 | 0.0001378 | 0.0000886 | FN1/SERPINE2/SLC7A11/DSP/IL6/ZNF703/VCL/TSPAN32/UBASH3B/ADAMTS18/CCL5/JUP/C1QTNF1/EMILIN2/DSG2/MYL9/MYH9/XG | 18 |
| IBRAHIM_NRF1_DOWN | IBRAHIM_NRF1_DOWN | IBRAHIM_NRF1_DOWN | 26/1438 | 166/23056 | 0.1566265 | 2.511252 | 5.039905 | 0.0000130 | 0.0001380 | 0.0000887 | AGRN/DHRS3/CCN1/GPR39/LYPD1/FN1/EPHA4/BHLHE40/RARB/PHLDB2/HES1/PDGFC/MOXD1/CITED2/PLAT/NRP1/FZD4/KCNH3/GLI1/DACT1/TPM1/MAF/HOXB3/NOG/FSTL3/GDF15 | 26 |
| HP_ABNORMAL_HEART_VALVE_MORPHOLOGY | HP_ABNORMAL_HEART_VALVE_MORPHOLOGY | HP_ABNORMAL_HEART_VALVE_MORPHOLOGY | 42/1438 | 335/23056 | 0.1253731 | 2.010155 | 4.803425 | 0.0000131 | 0.0001385 | 0.0000890 | MMP23B/HSPG2/TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/PLD1/SLC34A2/RREB1/TENT5A/GJA1/CITED2/TMEM270/SHH/TPM2/COL5A1/NOTCH1/MYPN/WT1/MYRF/ROBO4/VWF/GLI1/ZIC2/MMP14/DACT1/FBLN5/ACTC1/FBN1/SMAD6/HCN4/SALL1/MMP2/FOXF1/MYOCD/RNF135/COL1A1/GATA6/RRAS/JPH2/GATA5 | 42 |
| ROSS_AML_WITH_CBFB_MYH11_FUSION | ROSS_AML_WITH_CBFB_MYH11_FUSION | ROSS_AML_WITH_CBFB_MYH11_FUSION | 13/1438 | 52/23056 | 0.2500000 | 4.008345 | 5.601210 | 0.0000132 | 0.0001395 | 0.0000897 | MTMR11/CTSS/TGFBI/SPARC/MDFIC/CEBPD/NACC2/NRP1/SLC7A7/TNFAIP2/MN1/LGALS2/IL13RA1 | 13 |
| WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER | WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER | WU_SILENCED_BY_METHYLATION_IN_BLADDER_CANCER | 13/1438 | 52/23056 | 0.2500000 | 4.008345 | 5.601210 | 0.0000132 | 0.0001395 | 0.0000897 | PTPRC/COL5A2/COL6A3/MITF/JCHAIN/SLC4A4/LAMA2/KLF4/ZCCHC24/PLAAT4/IGF1/ANPEP/CNN1 | 13 |
| GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_D_UP | 11/1438 | 38/23056 | 0.2894737 | 4.641241 | 5.793776 | 0.0000134 | 0.0001418 | 0.0000912 | EVA1A/SERPINE2/NPR3/PLA2G7/PERP/HECW1/EPHB6/LOXL2/FABP4/CA13/SLC16A12 | 11 |
| GOBP_MACROPHAGE_CHEMOTAXIS | GOBP_MACROPHAGE_CHEMOTAXIS | GOBP_MACROPHAGE_CHEMOTAXIS | 11/1438 | 38/23056 | 0.2894737 | 4.641241 | 5.793776 | 0.0000134 | 0.0001418 | 0.0000912 | EDN2/CSF1/RARRES2/SFTPD/SAA1/C3AR1/EDNRB/THBS1/CYP19A1/CCL5/C5AR1 | 11 |
| HP_APLASIA_CUTIS_CONGENITA | HP_APLASIA_CUTIS_CONGENITA | HP_APLASIA_CUTIS_CONGENITA | 11/1438 | 38/23056 | 0.2894737 | 4.641241 | 5.793776 | 0.0000134 | 0.0001418 | 0.0000912 | LAMC2/LAMB3/ITGA6/COL7A1/FGFRL1/DSP/TFAP2A/NOTCH1/ALX4/MMP1/ITGB4 | 11 |
| REACTOME_SMOOTH_MUSCLE_CONTRACTION | REACTOME_SMOOTH_MUSCLE_CONTRACTION | REACTOME_SMOOTH_MUSCLE_CONTRACTION | 11/1438 | 38/23056 | 0.2894737 | 4.641241 | 5.793776 | 0.0000134 | 0.0001418 | 0.0000912 | LMOD1/ACTG2/MYLK/ITGB5/MYL7/TPM2/ANXA1/VCL/ANXA2/TPM1/MYL9 | 11 |
| GOBP_T_HELPER_1_TYPE_IMMUNE_RESPONSE | GOBP_T_HELPER_1_TYPE_IMMUNE_RESPONSE | GOBP_T_HELPER_1_TYPE_IMMUNE_RESPONSE | 12/1438 | 45/23056 | 0.2666667 | 4.275568 | 5.672563 | 0.0000139 | 0.0001462 | 0.0000940 | PLA2G4A/IL1R1/IL1B/LEF1/ANXA1/STAT6/IL4R/EBI3/IL27RA/IL12RB1/BCL3/RELB | 12 |
| HP_ABNORMAL_VERTEBRAL_MORPHOLOGY | HP_ABNORMAL_VERTEBRAL_MORPHOLOGY | HP_ABNORMAL_VERTEBRAL_MORPHOLOGY | 51/1438 | 439/23056 | 0.1161731 | 1.862648 | 4.706548 | 0.0000142 | 0.0001497 | 0.0000963 | HSPG2/FUCA1/PTCH2/TBX15/KYNU/FN1/WNT5A/FGFRL1/FGFR3/NKX3-2/SGMS2/SH3TC2/SPARC/RUNX2/TENT5A/GJA1/BMPER/GLI3/TMEM270/SHH/CSGALNACT1/GDF6/RSPO2/TPM2/GAS1/DKK1/PAPSS2/FGFR2/CREB3L1/SERPINH1/GRIP1/FREM2/ZIC2/MMP14/DACT1/FBN1/BNC1/SALL1/MMP2/FOXF1/MEOX1/COL1A1/NOG/SOX9/PIEZO2/TNFRSF11A/COL9A3/ARSL/PLS3/GPC4/BGN | 51 |
| HP_CONTRACTURES_OF_THE_JOINTS_OF_THE_UPPER_LIMBS | HP_CONTRACTURES_OF_THE_JOINTS_OF_THE_UPPER_LIMBS | HP_CONTRACTURES_OF_THE_JOINTS_OF_THE_UPPER_LIMBS | 38/1438 | 292/23056 | 0.1301370 | 2.086536 | 4.819094 | 0.0000143 | 0.0001503 | 0.0000966 | MMP23B/ECE1/HSPG2/TBX15/LAMC2/PRG4/LAMB3/NLRP3/ACTG2/COL6A3/TWIST2/TGFBR2/WNT5A/FGFR3/DOK7/ADAMTS3/FAT4/TFAP2A/PSMB8/COL12A1/GJA1/LAMA2/CCN2/GLI3/CAV1/SHH/TRPS1/TPM2/FGFR2/ITGA7/BMP4/FBN1/MMP2/NOG/ITGB4/PIEZO2/COL6A2/GPC4 | 38 |
| GOBP_METANEPHRIC_TUBULE_DEVELOPMENT | GOBP_METANEPHRIC_TUBULE_DEVELOPMENT | GOBP_METANEPHRIC_TUBULE_DEVELOPMENT | 8/1438 | 20/23056 | 0.4000000 | 6.413352 | 6.246431 | 0.0000144 | 0.0001511 | 0.0000972 | OSR1/WWTR1/HES1/YAP1/SOX8/SOX9/LIF/WNT7B | 8 |
| HP_ABNORMAL_HDL_CHOLESTEROL_CONCENTRATION | HP_ABNORMAL_HDL_CHOLESTEROL_CONCENTRATION | HP_ABNORMAL_HDL_CHOLESTEROL_CONCENTRATION | 8/1438 | 20/23056 | 0.4000000 | 6.413352 | 6.246431 | 0.0000144 | 0.0001511 | 0.0000972 | PPARG/PSMB8/APOC3/APOA1/SLC7A7/CETP/CREB3L3/APOE | 8 |
| MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_UP | MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_UP | MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_UP | 8/1438 | 20/23056 | 0.4000000 | 6.413352 | 6.246431 | 0.0000144 | 0.0001511 | 0.0000972 | PRG4/HSD11B1/NID1/COL6A3/THBS2/EBF2/CCN4/POSTN | 8 |
| GOBP_REGULATION_OF_MIRNA_TRANSCRIPTION | GOBP_REGULATION_OF_MIRNA_TRANSCRIPTION | GOBP_REGULATION_OF_MIRNA_TRANSCRIPTION | 14/1438 | 60/23056 | 0.2333333 | 3.741122 | 5.483175 | 0.0000146 | 0.0001526 | 0.0000981 | TGFB2/PPARG/KLF4/WT1/FOSL1/NFATC4/BMP4/FOS/SMAD6/SOX9/GATA6/TGFB1/BMP2/PDGFB | 14 |
| HP_ABNORMALITY_OF_RENAL_EXCRETION | HP_ABNORMALITY_OF_RENAL_EXCRETION | HP_ABNORMALITY_OF_RENAL_EXCRETION | 14/1438 | 60/23056 | 0.2333333 | 3.741122 | 5.483175 | 0.0000146 | 0.0001526 | 0.0000981 | PTPN22/CFH/AGT/GALNT3/CLDN16/CFI/ITPR3/CCN2/IL6/CAV1/C3/PLVAP/THBD/CYP24A1 | 14 |
| NADLER_OBESITY_UP | NADLER_OBESITY_UP | NADLER_OBESITY_UP | 14/1438 | 60/23056 | 0.2333333 | 3.741122 | 5.483175 | 0.0000146 | 0.0001526 | 0.0000981 | CD53/CTSS/FCGR2A/CAPG/CRYAB/SELPLG/ALOX5AP/POSTN/MFGE8/MT1X/CD68/COL1A1/FXYD5/BGN | 14 |
| ZHENG_GLIOBLASTOMA_PLASTICITY_DN | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | 14/1438 | 60/23056 | 0.2333333 | 3.741122 | 5.483175 | 0.0000146 | 0.0001526 | 0.0000981 | CCN1/CD109/CAV1/CLU/TRIM5/SERPINH1/CRYAB/EMP1/ITGA5/ITGA7/CSPG4/ZFP36/COL9A3/COL6A2 | 14 |
| GOBP_TEMPERATURE_HOMEOSTASIS | GOBP_TEMPERATURE_HOMEOSTASIS | GOBP_TEMPERATURE_HOMEOSTASIS | 27/1438 | 177/23056 | 0.1525424 | 2.445770 | 4.979910 | 0.0000146 | 0.0001534 | 0.0000986 | EDN2/PTGS2/IL1A/IL1B/TRPM8/PLAC8/IL15/PDGFC/NPR3/ADRB2/LAMA4/GJA1/CD36/CAV1/EBF2/FABP4/NOTCH1/WNT10B/STAT6/FOXO1/EDNRB/DIO2/IL4R/TRPV2/TNFRSF11A/CEBPB/ADAMTS5 | 27 |
| GOBP_NEGATIVE_REGULATION_OF_PROTEOLYSIS | GOBP_NEGATIVE_REGULATION_OF_PROTEOLYSIS | GOBP_NEGATIVE_REGULATION_OF_PROTEOLYSIS | 43/1438 | 348/23056 | 0.1235632 | 1.981136 | 4.756458 | 0.0000149 | 0.0001554 | 0.0000999 | ECM1/IFI16/PTGS2/AGT/CRIM1/TFPI/EPHA4/SERPINE2/COL6A3/COL7A1/ITIH3/SERPINB1/HFE/CD109/AQP1/SERPINE1/SHH/PLAT/GAS1/KLF4/PTPN3/CRB2/ANXA8L1/ANXA8/CD44/SERPINH1/BIRC3/CARD16/CRYAB/SERPINE3/SERPINA10/SERPINA6/SERPINA1/THBS1/ANXA2/SERPINB7/SERPINB2/SERPINB8/TNFSF14/C3/PRNP/WFDC10B/BIRC7 | 43 |
| HP_PROTRUSIO_ACETABULI | HP_PROTRUSIO_ACETABULI | HP_PROTRUSIO_ACETABULI | 7/1438 | 15/23056 | 0.4666667 | 7.482244 | 6.477010 | 0.0000149 | 0.0001557 | 0.0001001 | HSPG2/TGFB2/TGFBR2/TENT5A/FBN1/MMP2/COL1A1 | 7 |
| HUMMEL_BURKITTS_LYMPHOMA_DN | HUMMEL_BURKITTS_LYMPHOMA_DN | HUMMEL_BURKITTS_LYMPHOMA_DN | 7/1438 | 15/23056 | 0.4666667 | 7.482244 | 6.477010 | 0.0000149 | 0.0001557 | 0.0001001 | S100A11/MDFIC/CD44/NFKBIA/CRIP1/BCL2A1/BCL3 | 7 |
| REACTOME_ANCHORING_FIBRIL_FORMATION | REACTOME_ANCHORING_FIBRIL_FORMATION | REACTOME_ANCHORING_FIBRIL_FORMATION | 7/1438 | 15/23056 | 0.4666667 | 7.482244 | 6.477010 | 0.0000149 | 0.0001557 | 0.0001001 | LAMC2/LAMB3/COL7A1/TLL2/COL1A1/COL4A6/COL4A5 | 7 |
| SA_MMP_CYTOKINE_CONNECTION | SA_MMP_CYTOKINE_CONNECTION | SA_MMP_CYTOKINE_CONNECTION | 7/1438 | 15/23056 | 0.4666667 | 7.482244 | 6.477010 | 0.0000149 | 0.0001557 | 0.0001001 | TNFRSF1B/CSF1/TGFB2/IL1B/CD44/TNFRSF1A/TGFB1 | 7 |
| WP_SARSCOV2_INNATE_IMMUNITY_EVASION_AND_CELLSPECIFIC_IMMUNE_RESPONSE | WP_SARSCOV2_INNATE_IMMUNITY_EVASION_AND_CELLSPECIFIC_IMMUNE_RESPONSE | WP_SARSCOV2_INNATE_IMMUNITY_EVASION_AND_CELLSPECIFIC_IMMUNE_RESPONSE | 15/1438 | 68/23056 | 0.2205882 | 3.536775 | 5.403063 | 0.0000150 | 0.0001568 | 0.0001008 | CASP8/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/CSF2/TFAP2A/IL6/DDX58/CCL5/DHX58/TGFB1/MX1 | 15 |
| GOBP_SKIN_EPIDERMIS_DEVELOPMENT | GOBP_SKIN_EPIDERMIS_DEVELOPMENT | GOBP_SKIN_EPIDERMIS_DEVELOPMENT | 18/1438 | 93/23056 | 0.1935484 | 3.103235 | 5.241664 | 0.0000152 | 0.0001578 | 0.0001015 | TGFB2/WNT5A/FST/CD109/PDGFA/INHBA/SHH/FZD6/EXT1/NOTCH1/DKK1/FGFR2/ALX4/WNT10B/TNFRSF19/KRT17/SOX9/GATA6 | 18 |
| BASAKI_YBX1_TARGETS_UP | BASAKI_YBX1_TARGETS_UP | BASAKI_YBX1_TARGETS_UP | 38/1438 | 293/23056 | 0.1296928 | 2.079414 | 4.795805 | 0.0000154 | 0.0001606 | 0.0001032 | EPHA2/CDA/CCN1/S100A2/LAMC2/PHLDB2/ANXA3/PLAC8/OSMR/PLK2/ADRB2/TNFRSF21/CCN2/CAV1/RBPMS/MYBL1/PROSER2/ANXA8/DKK1/PRSS23/KRT80/AJUBA/NFKBIA/FRMD6/NID2/THBS1/EHD4/FBN1/TNFRSF12A/MT2A/MT1X/RRAD/COTL1/CAVIN1/AXL/EHD2/RRAS/ZNF185 | 38 |
| GOCC_APICAL_PLASMA_MEMBRANE | GOCC_APICAL_PLASMA_MEMBRANE | GOCC_APICAL_PLASMA_MEMBRANE | 44/1438 | 360/23056 | 0.1222222 | 1.959635 | 4.733006 | 0.0000156 | 0.0001624 | 0.0001044 | ADCY10/CD34/LCT/DPP4/CYBRD1/FN1/KCNE4/MUC13/PLD1/CLDN1/SLC34A2/ABCG2/OSMR/ADRB2/CLIC5/GJA1/SLC22A1/AQP1/CD36/SLC26A4/PODXL/ATP6V0A4/STC1/FZD6/ANXA13/ADCY8/TEK/ANXA1/TRPM6/CRB2/NOTCH1/SLC22A18/SLC5A12/CD44/SLCO2B1/KCNA5/SCNN1A/SLC10A2/SLC24A4/CSPG4/SLC47A1/SLC16A3/SLC14A2/MSN | 44 |
| GOBP_BASEMENT_MEMBRANE_ORGANIZATION | GOBP_BASEMENT_MEMBRANE_ORGANIZATION | GOBP_BASEMENT_MEMBRANE_ORGANIZATION | 10/1438 | 32/23056 | 0.3125000 | 5.010431 | 5.855041 | 0.0000157 | 0.0001627 | 0.0001046 | CTSS/HMCN1/LAMB3/NID1/LAMB2/PHLDB2/CAV2/CAV1/EXT1/NID2 | 10 |
| GOBP_METANEPHROS_MORPHOGENESIS | GOBP_METANEPHROS_MORPHOGENESIS | GOBP_METANEPHROS_MORPHOGENESIS | 10/1438 | 32/23056 | 0.3125000 | 5.010431 | 5.855041 | 0.0000157 | 0.0001627 | 0.0001046 | HES1/GDNF/WT1/BMP4/SOX8/SALL1/LHX1/SOX9/LIF/WNT7B | 10 |
| GOBP_POSITIVE_REGULATION_OF_NEUTROPHIL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_NEUTROPHIL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_NEUTROPHIL_MIGRATION | 10/1438 | 32/23056 | 0.3125000 | 5.010431 | 5.855041 | 0.0000157 | 0.0001627 | 0.0001046 | IL1R1/IL1A/CXCL8/EDN1/C3AR1/NCKAP1L/CCR7/C5AR1/RAC2/XG | 10 |
| LI_PROSTATE_CANCER_EPIGENETIC | LI_PROSTATE_CANCER_EPIGENETIC | LI_PROSTATE_CANCER_EPIGENETIC | 10/1438 | 32/23056 | 0.3125000 | 5.010431 | 5.855041 | 0.0000157 | 0.0001627 | 0.0001046 | LAMC2/PTGS2/LAMB3/RARB/CAV1/PLAU/CD44/EDNRB/CDH13/DDX53 | 10 |
| BROWNE_HCMV_INFECTION_20HR_DN | BROWNE_HCMV_INFECTION_20HR_DN | BROWNE_HCMV_INFECTION_20HR_DN | 19/1438 | 102/23056 | 0.1862745 | 2.986610 | 5.186063 | 0.0000157 | 0.0001630 | 0.0001048 | LTBP1/TFPI/TMEM158/MGLL/LPP/LRRC15/FST/CAP2/CCN2/AHR/ANXA1/VCL/ANXA2/NQO1/ITGA3/WIPI1/SERPINB2/AXL/SRPX2 | 19 |
| KOBAYASHI_EGFR_SIGNALING_24HR_UP | KOBAYASHI_EGFR_SIGNALING_24HR_UP | KOBAYASHI_EGFR_SIGNALING_24HR_UP | 19/1438 | 102/23056 | 0.1862745 | 2.986610 | 5.186063 | 0.0000157 | 0.0001630 | 0.0001048 | NIBAN1/HEG1/BCL6/EDIL3/GPNMB/AKR1B10/CEBPD/AQP3/GSN/ANXA8/SCNN1A/DRAM1/AHNAK2/NUPR1/PSMB10/PSG4/PSG9/BCAM/HMOX1 | 19 |
| REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 29/1438 | 198/23056 | 0.1464646 | 2.348323 | 4.914301 | 0.0000159 | 0.0001648 | 0.0001059 | ECE1/EDN2/AGT/ACKR3/ACKR2/CCR3/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/F2RL1/EDN1/HCRTR2/GPR37/PNOC/ANXA1/NPY4R/CCKBR/SAA1/C3AR1/EDNRB/BDKRB1/CCL5/CCR7/C3/C5AR1/FPR1 | 29 |
| SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | 26/1438 | 168/23056 | 0.1547619 | 2.481356 | 4.970093 | 0.0000161 | 0.0001668 | 0.0001072 | RHOC/S100A11/PRRX1/VAMP5/TGFBR2/SEL1L3/SPARC/IER3/DDR1/RUNX2/CYP39A1/ARHGAP18/VNN1/CAV2/PTGR1/TOR4A/PTPRE/TAGLN/AJUBA/ANXA2/TPM1/MEOX1/DSG2/SIRPA/LGALS1/PNPLA3 | 26 |
| SMIRNOV_RESPONSE_TO_IR_6HR_UP | SMIRNOV_RESPONSE_TO_IR_6HR_UP | SMIRNOV_RESPONSE_TO_IR_6HR_UP | 26/1438 | 168/23056 | 0.1547619 | 2.481356 | 4.970093 | 0.0000161 | 0.0001668 | 0.0001072 | FUCA1/CSF1/KCNN3/MR1/NABP1/PLK2/SPARC/IER3/DDR1/TENT5A/PODXL/MYBL1/FZD6/NOTCH1/FAS/FOSL1/DRAM1/ORAI3/MT1X/RRAD/TNFSF9/CD70/GDF15/PROCR/APOBEC3G/ITM2A | 26 |
| GOBP_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | GOBP_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | GOBP_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | 28/1438 | 188/23056 | 0.1489362 | 2.387950 | 4.928253 | 0.0000162 | 0.0001669 | 0.0001073 | TNFRSF1B/ZC3H12A/MR1/PLA2G4A/PTPRC/NLRP3/IL1R1/IL1B/BCL6/IL7R/HFE/HLA-E/TNFAIP3/AHR/IL6/CD274/ANXA1/KLRD1/NCKAP1L/STAT6/TNFSF13B/IL4R/C3/IL27RA/IL12RB1/TGFB1/NECTIN2/IL4I1 | 28 |
| PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP | 13/1438 | 53/23056 | 0.2452830 | 3.932716 | 5.512771 | 0.0000165 | 0.0001696 | 0.0001091 | FUCA1/CTSS/SEL1L3/CXCL2/DAB2/PLA2G7/SOD2/SRGN/PAPSS2/MS4A4A/NCKAP1L/SIGLEC15/SAT1 | 13 |
| WP_CARDIAC_PROGENITOR_DIFFERENTIATION | WP_CARDIAC_PROGENITOR_DIFFERENTIATION | WP_CARDIAC_PROGENITOR_DIFFERENTIATION | 13/1438 | 53/23056 | 0.2452830 | 3.932716 | 5.512771 | 0.0000165 | 0.0001696 | 0.0001091 | KDR/IRX4/INHBA/NOTCH1/DKK1/IGF1/BMP4/ACTC1/ANPEP/MYLK3/NOG/TGFB1/SIRPA | 13 |
| ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | 9/1438 | 26/23056 | 0.3461538 | 5.550016 | 5.986967 | 0.0000165 | 0.0001697 | 0.0001091 | BCL6/RUNX2/CD36/FAS/CD44/TNFRSF1A/SERPINA1/APOE/HMOX1 | 9 |
| SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_UP | SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_UP | SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_UP | 9/1438 | 26/23056 | 0.3461538 | 5.550016 | 5.986967 | 0.0000165 | 0.0001697 | 0.0001091 | GBP1/GBP2/GBP5/IL1B/HLA-C/ANKRD22/PLAAT4/RHBDF2/APOL6 | 9 |
| WP_EICOSANOID_SYNTHESIS | WP_EICOSANOID_SYNTHESIS | WP_EICOSANOID_SYNTHESIS | 9/1438 | 26/23056 | 0.3461538 | 5.550016 | 5.986967 | 0.0000165 | 0.0001697 | 0.0001091 | PTGS2/PLA2G4A/PTGS1/ALOX5/ALOX5AP/PTGIS/GGTLC2/GGT1/PNPLA3 | 9 |
| GOMF_AMYLOID_BETA_BINDING | GOMF_AMYLOID_BETA_BINDING | GOMF_AMYLOID_BETA_BINDING | 17/1438 | 85/23056 | 0.2000000 | 3.206676 | 5.256690 | 0.0000165 | 0.0001699 | 0.0001092 | HSPG2/LDLRAP1/TGFB2/EPHA4/ITGA2/ADRB2/CD36/MSR1/CLU/FZD6/FZD4/CRYAB/APOA1/CACNA1A/APOE/PRNP/ITM2A | 17 |
| HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | 17/1438 | 85/23056 | 0.2000000 | 3.206676 | 5.256690 | 0.0000165 | 0.0001699 | 0.0001092 | CTSS/IL1B/MITF/CXCL3/DAB2/TGFBI/MSR1/ANXA1/KLF4/C3AR1/PHLDA1/ZFP36L1/FOS/TRPV2/ZFP36/FPR1/SIRPA | 17 |
| HP_ABNORMAL_VASCULAR_PHYSIOLOGY | HP_ABNORMAL_VASCULAR_PHYSIOLOGY | HP_ABNORMAL_VASCULAR_PHYSIOLOGY | 37/1438 | 283/23056 | 0.1307420 | 2.096237 | 4.785659 | 0.0000166 | 0.0001702 | 0.0001094 | HSPG2/PTPN22/TGFB2/COL3A1/COL5A2/TGFBR2/LAMB2/MYLK/FGFR3/SLC34A2/SPP1/STING1/HFE/NT5E/GJA1/LAMA2/CCN2/CITED2/TMEM270/EPHB4/CAV1/FLNC/COL5A1/NOTCH1/MYPN/FAS/HTRA1/SCNN1A/KRT8/KRT18/ACTC1/FBN1/FOXF1/PIEZO1/COL1A1/GATA6/KCNN4 | 37 |
| HP_DYSPNEA | HP_DYSPNEA | HP_DYSPNEA | 46/1438 | 384/23056 | 0.1197917 | 1.920665 | 4.692202 | 0.0000170 | 0.0001740 | 0.0001119 | AGRN/LDLRAP1/PRRX1/LAMC2/LAMB3/TGFB2/NABP1/EPHA4/TGFBR2/LAMB2/TNNC1/MYLK/DOK7/SLC34A2/SPP1/DSP/EDN1/RUNX2/CCN2/CITED2/FAM20C/BMPER/PON3/EPHB4/CAV1/FLNC/ZFPM2/MYPN/COL13A1/VCL/FGFR2/PYGM/SCNN1A/SERPINA1/ACTC1/FBN1/FOXF1/KRT17/ITGA3/SOX9/GATA6/CACNA1A/SCN1B/JPH2/COL4A6/COL4A5 | 46 |
| GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE | GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE | GOBP_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 32/1438 | 230/23056 | 0.1391304 | 2.230731 | 4.838006 | 0.0000174 | 0.0001778 | 0.0001143 | GBP5/PTPN22/IFI16/CFH/IKBKE/NMI/CASP8/PPARG/WNT5A/CD96/PARP14/TXK/EREG/STING1/HLA-E/MICA/TNFAIP3/RAET1E/TRIM56/MBL2/TRIM5/BIRC3/KLRD1/KLRC4-KLRK1/NLRC5/RNF135/CCL5/DHX58/IFI35/NECTIN2/APOE/USP18 | 32 |
| HP_ABNORMALITY_OF_THE_NAIL | HP_ABNORMALITY_OF_THE_NAIL | HP_ABNORMALITY_OF_THE_NAIL | 52/1438 | 454/23056 | 0.1145374 | 1.836422 | 4.642312 | 0.0000174 | 0.0001781 | 0.0001145 | TNFRSF1B/ECE1/FUCA1/KCNN3/LAMC2/LAMB3/ACTG2/ITGA6/IL17RC/COL7A1/WNT5A/SLCO2A1/FGFRL1/FGFR3/VEGFC/STING1/DSP/TFAP2A/HFE/HLA-C/RUNX2/GJA1/PERP/SASH1/BMPER/GLI3/TMEM270/PLAG1/FZD6/ANGPT1/TRPS1/COL14A1/GSN/NOTCH1/MYOF/NFKB2/FGFR2/MMP1/GLI1/HMGA2/PRKD1/BMP4/MAF/KRT17/JUP/DLX3/ITGA3/NOG/ITGB4/SCN1B/BMP2/GPC4 | 52 |
| GOBP_POSITIVE_REGULATION_OF_STEROL_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_STEROL_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_STEROL_TRANSPORT | 11/1438 | 39/23056 | 0.2820513 | 4.522235 | 5.677806 | 0.0000177 | 0.0001800 | 0.0001157 | LDLRAP1/PPARG/CAV1/APOA1/NFKBIA/ANXA2/CES1/CETP/ABCA8/LIPG/APOE | 11 |
| HP_AORTIC_DISSECTION | HP_AORTIC_DISSECTION | HP_AORTIC_DISSECTION | 11/1438 | 39/23056 | 0.2820513 | 4.522235 | 5.677806 | 0.0000177 | 0.0001800 | 0.0001157 | PTPN22/TGFB2/COL3A1/TGFBR2/MYLK/TENT5A/NOTCH1/FBN1/SMAD6/GATA5/BGN | 11 |
| NEWMAN_ERCC6_TARGETS_DN | NEWMAN_ERCC6_TARGETS_DN | NEWMAN_ERCC6_TARGETS_DN | 11/1438 | 39/23056 | 0.2820513 | 4.522235 | 5.677806 | 0.0000177 | 0.0001800 | 0.0001157 | LBH/GALNT5/CCDC80/FGF5/HAPLN1/SERPINE1/PODXL/PTGS1/PAMR1/PSG5/PSG9 | 11 |
| GOBP_REGULATION_OF_NEUTROPHIL_MIGRATION | GOBP_REGULATION_OF_NEUTROPHIL_MIGRATION | GOBP_REGULATION_OF_NEUTROPHIL_MIGRATION | 12/1438 | 46/23056 | 0.2608696 | 4.182621 | 5.572624 | 0.0000177 | 0.0001800 | 0.0001157 | IL1R1/IL1A/DPP4/SLIT2/CXCL8/EDN1/C3AR1/NCKAP1L/CCR7/C5AR1/RAC2/XG | 12 |
| GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_DN | 12/1438 | 46/23056 | 0.2608696 | 4.182621 | 5.572624 | 0.0000177 | 0.0001800 | 0.0001157 | GBP2/TM4SF1/CXCL6/CXCL1/CRHBP/VNN1/ADGRG6/RBPMS/ALOX5/MPZL2/EMP1/GLIPR1 | 12 |
| HP_PNEUMOTHORAX | HP_PNEUMOTHORAX | HP_PNEUMOTHORAX | 12/1438 | 46/23056 | 0.2608696 | 4.182621 | 5.572624 | 0.0000177 | 0.0001800 | 0.0001157 | LAMC2/LAMB3/TGFB2/COL3A1/TGFBR2/MYLK/SLC34A2/ADAMTS2/EXT1/EFEMP2/FBLN5/FBN1 | 12 |
| STOSSI_RESPONSE_TO_ESTRADIOL | STOSSI_RESPONSE_TO_ESTRADIOL | STOSSI_RESPONSE_TO_ESTRADIOL | 12/1438 | 46/23056 | 0.2608696 | 4.182621 | 5.572624 | 0.0000177 | 0.0001800 | 0.0001157 | PTGS2/PLA2G4A/CD34/AGT/ITGA6/CXCL8/BMP6/GJA1/BIRC3/SERPINA6/CA12/KRT19 | 12 |
| WP_HEART_DEVELOPMENT | WP_HEART_DEVELOPMENT | WP_HEART_DEVELOPMENT | 12/1438 | 46/23056 | 0.2608696 | 4.182621 | 5.572624 | 0.0000177 | 0.0001800 | 0.0001157 | BMP10/BHLHE40/VEGFC/IRX4/FOXC1/SHH/NOTCH1/NFATC4/BMP4/GATA6/BMP2/NFATC2 | 12 |
| GOMF_PHOSPHATIDYLSERINE_BINDING | GOMF_PHOSPHATIDYLSERINE_BINDING | GOMF_PHOSPHATIDYLSERINE_BINDING | 14/1438 | 61/23056 | 0.2295082 | 3.679792 | 5.405098 | 0.0000178 | 0.0001813 | 0.0001166 | RPE65/CAVIN2/OSBPL10/MME/SCIN/ANXA13/GSDMD/SYT12/SYTL2/THBS1/ANXA2/MFGE8/AXL/JPH2 | 14 |
| GOBP_EPITHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_EPITHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_EPITHELIAL_CELL_APOPTOTIC_PROCESS | 21/1438 | 121/23056 | 0.1735537 | 2.782653 | 5.070658 | 0.0000179 | 0.0001814 | 0.0001166 | ITGA4/TGFBR2/KDR/SEMA5A/TNFAIP3/IL6/SERPINE1/ANGPT1/TEK/GSN/AKR1C3/TCF7L2/YAP1/KRT18/ZFP36L1/THBS1/NUPR1/ICAM1/ZFP36/IL11/HMOX1 | 21 |
| GOBP_ENDOTHELIAL_CELL_DEVELOPMENT | GOBP_ENDOTHELIAL_CELL_DEVELOPMENT | GOBP_ENDOTHELIAL_CELL_DEVELOPMENT | 15/1438 | 69/23056 | 0.2173913 | 3.485517 | 5.332789 | 0.0000181 | 0.0001838 | 0.0001182 | IL1B/HEG1/CLDN1/F2RL1/MET/STC1/S1PR3/VCL/ROBO4/TNFRSF1A/EDNRB/PECAM1/ICAM1/COL18A1/MSN | 15 |
| GOBP_NEGATIVE_REGULATION_OF_CHEMOTAXIS | GOBP_NEGATIVE_REGULATION_OF_CHEMOTAXIS | GOBP_NEGATIVE_REGULATION_OF_CHEMOTAXIS | 15/1438 | 69/23056 | 0.2173913 | 3.485517 | 5.332789 | 0.0000181 | 0.0001838 | 0.0001182 | DPP4/SEMA3B/WNT5A/SLIT2/SEMA5A/SEMA3C/SEMA3A/SEMA3D/NOTCH1/NRP1/KLRC4-KLRK1/THBS1/CYP19A1/ELANE/SEMA6B | 15 |
| GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | 15/1438 | 69/23056 | 0.2173913 | 3.485517 | 5.332789 | 0.0000181 | 0.0001838 | 0.0001182 | RUNX3/PTPN22/PTPRC/ITPKB/NLRP3/TGFBR2/HLA-E/GLI3/SHH/ANXA1/NCKAP1L/IL4R/EBI3/IL12RB1/RUNX1 | 15 |
| GOBP_ACTIN_MEDIATED_CELL_CONTRACTION | GOBP_ACTIN_MEDIATED_CELL_CONTRACTION | GOBP_ACTIN_MEDIATED_CELL_CONTRACTION | 19/1438 | 103/23056 | 0.1844660 | 2.957614 | 5.135469 | 0.0000182 | 0.0001841 | 0.0001184 | KCNE4/TNNC1/DSP/GJA1/CAV1/STC1/GSN/KCNA5/FRMD6/ACTC1/TPM1/HCN4/MYH8/MYH4/MYH2/JUP/KCNJ2/DSG2/SCN1B | 19 |
| GOCC_GOLGI_LUMEN | GOCC_GOLGI_LUMEN | GOCC_GOLGI_LUMEN | 19/1438 | 103/23056 | 0.1844660 | 2.957614 | 5.135469 | 0.0000182 | 0.0001841 | 0.0001184 | AGRN/HSPG2/PRELP/WNT5A/MUC13/SOD3/PDGFA/PCSK5/LUM/MMP14/CSPG4/RHBDF2/MUC16/TGFB1/SDC4/PDGFB/WNT7B/GPC4/BGN | 19 |
| BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | 24/1438 | 150/23056 | 0.1600000 | 2.565341 | 4.960599 | 0.0000192 | 0.0001942 | 0.0001248 | TNFRSF9/DHRS3/GFI1/CSF1/RASGRP3/IL1B/DPP4/NABP1/BHLHE40/BCL6/JCHAIN/SEMA5A/ELL2/TMEM71/APBB1IP/ALOX5/LRRC32/BCL9L/DACT1/IL4R/MEOX1/PECAM1/LIF/CYSLTR1 | 24 |
| GOBP_RESPONSE_TO_NUTRIENT | GOBP_RESPONSE_TO_NUTRIENT | GOBP_RESPONSE_TO_NUTRIENT | 24/1438 | 150/23056 | 0.1600000 | 2.565341 | 4.960599 | 0.0000192 | 0.0001942 | 0.0001248 | VCAM1/PTGS2/CYP26B1/IL1A/KYNU/PPARG/TGFBR2/SPP1/IL15/ITGA2/SOD2/STC1/TNFRSF11B/AQP3/AKR1C3/CYP26A1/POSTN/ALDH1A2/NQO1/COL1A1/LIPG/CYP24A1/MN1/HMOX1 | 24 |
| ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_DN | 36/1438 | 274/23056 | 0.1313869 | 2.106575 | 4.752418 | 0.0000193 | 0.0001945 | 0.0001251 | EPHA2/CDA/TRPM8/BHLHE40/VIPR1/STAB1/ITIH3/MYO10/C9/GRAMD2B/LECT2/IER3/TNFRSF21/TENT5A/VNN1/SLC22A1/TRIP6/CPED1/SH2D4A/TCIM/PGGHG/BBOX1/C1RL/FOS/ANPEP/MT2A/MT1X/PIEZO1/CD68/LIPG/C3/AXL/PRNP/MXRA5/CHST7/BGN | 36 |
| GOBP_ERBB_SIGNALING_PATHWAY | GOBP_ERBB_SIGNALING_PATHWAY | GOBP_ERBB_SIGNALING_PATHWAY | 21/1438 | 122/23056 | 0.1721311 | 2.759844 | 5.026532 | 0.0000203 | 0.0002049 | 0.0001317 | ERRFI1/AGT/EFEMP1/TGFA/ZFYVE28/EPGN/EREG/BTC/EGF/HBEGF/SH3TC2/PTPN3/PTPRJ/GPRC5A/RHBDF1/CDH13/GRB7/HAP1/SOX9/RHBDF2/TGFB1 | 21 |
| HP_CUTIS_LAXA | HP_CUTIS_LAXA | HP_CUTIS_LAXA | 21/1438 | 122/23056 | 0.1721311 | 2.759844 | 5.026532 | 0.0000203 | 0.0002049 | 0.0001317 | TBX15/COL3A1/TWIST2/CD96/FGFR3/OSMR/ADAMTS2/FOXC1/TENT5A/TMEM270/FGF20/TRPS1/EXT1/GSN/FGFR2/EFEMP2/C1R/SLC7A7/FBLN5/FBN1/RIN2 | 21 |
| GOBP_STRIATED_MUSCLE_ADAPTATION | GOBP_STRIATED_MUSCLE_ADAPTATION | GOBP_STRIATED_MUSCLE_ADAPTATION | 13/1438 | 54/23056 | 0.2407407 | 3.859888 | 5.426469 | 0.0000205 | 0.0002054 | 0.0001321 | ERRFI1/TRIM63/ATP2B4/BMP10/PPARG/TNNC1/MYOZ2/TRPC3/IL15/GSN/MYOZ1/FOXO1/GATA6 | 13 |
| GOMF_CELL_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_CELL_ADHESION_MEDIATOR_ACTIVITY | GOMF_CELL_CELL_ADHESION_MEDIATOR_ACTIVITY | 13/1438 | 54/23056 | 0.2407407 | 3.859888 | 5.426469 | 0.0000205 | 0.0002054 | 0.0001321 | NEXN/S100A11/DSP/ANXA1/MYPN/ROBO4/KRT18/GLDN/ANXA2/JUP/DSG2/SIRPA/CDC42EP1 | 13 |
| GOBP_GLOMERULAR_BASEMENT_MEMBRANE_DEVELOPMENT | GOBP_GLOMERULAR_BASEMENT_MEMBRANE_DEVELOPMENT | GOBP_GLOMERULAR_BASEMENT_MEMBRANE_DEVELOPMENT | 6/1438 | 11/23056 | 0.5454545 | 8.745480 | 6.626902 | 0.0000205 | 0.0002054 | 0.0001321 | NID1/LAMB2/SULF1/EXT1/WT1/MYO1E | 6 |
| GOBP_REGULATION_OF_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | GOBP_REGULATION_OF_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | GOBP_REGULATION_OF_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | 6/1438 | 11/23056 | 0.5454545 | 8.745480 | 6.626902 | 0.0000205 | 0.0002054 | 0.0001321 | CSF1/RUNX2/RSPO2/TNFRSF11B/BMP4/BMP2 | 6 |
| GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_ACTIVATION | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_ACTIVATION | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA_ACTIVATION | 6/1438 | 11/23056 | 0.5454545 | 8.745480 | 6.626902 | 0.0000205 | 0.0002054 | 0.0001321 | LTBP1/ITGB6/ITGB8/LRRC32/GATA6/PSG9 | 6 |
| HP_ARTERIAL_DISSECTION | HP_ARTERIAL_DISSECTION | HP_ARTERIAL_DISSECTION | 6/1438 | 11/23056 | 0.5454545 | 8.745480 | 6.626902 | 0.0000205 | 0.0002054 | 0.0001321 | COL3A1/COL5A2/TGFBR2/TENT5A/COL5A1/COL1A1 | 6 |
| HP_DILATATION_OF_THE_BLADDER | HP_DILATATION_OF_THE_BLADDER | HP_DILATATION_OF_THE_BLADDER | 6/1438 | 11/23056 | 0.5454545 | 8.745480 | 6.626902 | 0.0000205 | 0.0002054 | 0.0001321 | LMOD1/ACTG2/MYLK/FOXF1/MYOCD/MYL9 | 6 |
| PID_INTEGRIN4_PATHWAY | PID_INTEGRIN4_PATHWAY | PID_INTEGRIN4_PATHWAY | 6/1438 | 11/23056 | 0.5454545 | 8.745480 | 6.626902 | 0.0000205 | 0.0002054 | 0.0001321 | LAMC2/LAMB3/ITGA6/LAMB2/LAMA2/ITGB4 | 6 |
| GOBP_REGULATION_OF_MUSCLE_ADAPTATION | GOBP_REGULATION_OF_MUSCLE_ADAPTATION | GOBP_REGULATION_OF_MUSCLE_ADAPTATION | 18/1438 | 95/23056 | 0.1894737 | 3.037904 | 5.133390 | 0.0000205 | 0.0002054 | 0.0001321 | ERRFI1/TNFRSF1B/TRIM63/CASQ1/ATP2B4/AGT/BMP10/PPARG/TNNC1/TRPC3/EDN1/FBXO32/NOTCH1/TNFRSF1A/IGF1/FOXO1/SGCA/GATA5 | 18 |
| GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | 18/1438 | 95/23056 | 0.1894737 | 3.037904 | 5.133390 | 0.0000205 | 0.0002054 | 0.0001321 | ECE1/EDN2/AGT/SUCNR1/ADAMTS16/F2RL1/ADRB2/EDN1/SOD2/PCSK5/ADM/ARHGAP42/SPX/EDNRB/TPM1/KCNK6/ADRA1D/PDGFB | 18 |
| HP_INCREASED_CIRCULATING_ANTIBODY_LEVEL | HP_INCREASED_CIRCULATING_ANTIBODY_LEVEL | HP_INCREASED_CIRCULATING_ANTIBODY_LEVEL | 18/1438 | 95/23056 | 0.1894737 | 3.037904 | 5.133390 | 0.0000205 | 0.0002054 | 0.0001321 | CASP10/COL7A1/IL7R/STING1/PSMB8/PSMB9/PLA2G7/TNFSF15/FAS/NCKAP1L/SLC7A7/IL4R/COL1A1/ELANE/IL12RB1/TGFB1/IL2RB/GPC4 | 18 |
| KOYAMA_SEMA3B_TARGETS_DN | KOYAMA_SEMA3B_TARGETS_DN | KOYAMA_SEMA3B_TARGETS_DN | 44/1438 | 364/23056 | 0.1208791 | 1.938101 | 4.652840 | 0.0000205 | 0.0002054 | 0.0001321 | DHRS3/S100A10/TGFB2/HHIPL2/NLRP3/FN1/TWIST2/TMEM158/LPP/HES1/NKD2/SLC12A7/MYO10/GDNF/ID4/PSMB9/ADGRG6/STX11/TNS3/CAV2/CAV1/NIPAL2/FBXO32/TRAF1/AIF1L/DKK1/PLPP4/ADM/EFEMP2/BIRC3/AMIGO2/STAT6/NFKBIA/SMAD6/RRAD/NQO1/OSGIN1/SLFN11/ATP8B3/CD70/MYL9/ICOSLG/CELSR1/FAM133A | 44 |
| REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER | REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER | REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER | 16/1438 | 78/23056 | 0.2051282 | 3.288898 | 5.222422 | 0.0000209 | 0.0002087 | 0.0001342 | TGFA/FGFR3/EPGN/EREG/BTC/FGF5/EGF/HBEGF/FGF18/PDGFA/MET/FGF20/FGFR2/FLT3/RAC2/PDGFB | 16 |
| WP_INTEGRINMEDIATED_CELL_ADHESION | WP_INTEGRINMEDIATED_CELL_ADHESION | WP_INTEGRINMEDIATED_CELL_ADHESION | 19/1438 | 104/23056 | 0.1826923 | 2.929175 | 5.085484 | 0.0000210 | 0.0002093 | 0.0001346 | ITGA10/ITGB6/ITGA6/ITGA4/ITGB5/ITGA2/ITGB8/CAV2/CAV1/ZYX/ITGA8/MYPN/VCL/ITGA5/ITGA7/ITGA11/ITGA3/ITGB4/RAC2 | 19 |
| GOBP_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | GOBP_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | GOBP_ORGANIC_HYDROXY_COMPOUND_TRANSPORT | 37/1438 | 286/23056 | 0.1293706 | 2.074248 | 4.714770 | 0.0000210 | 0.0002093 | 0.0001346 | LDLRAP1/AGT/PPARG/OSBPL10/SPP1/EGF/GDNF/DAB2/BMP6/SLC22A1/AQP1/CD36/CAV1/SHH/MSR1/FGF20/CLU/AQP7/AQP3/SLC5A12/SYT12/SLCO2B1/APOC3/APOA1/SOAT2/SLC10A2/NFKBIA/CYP19A1/ANXA2/CES1/CETP/ABCC3/ABCA8/C1QTNF1/SLC16A3/LIPG/APOE | 37 |
| WP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_PART_2_OF_3 | WP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_PART_2_OF_3 | WP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_PART_2_OF_3 | 10/1438 | 33/23056 | 0.3030303 | 4.858600 | 5.720843 | 0.0000213 | 0.0002118 | 0.0001361 | WNT5A/LEF1/RUNX2/PDGFA/INHBA/FZD1/SHH/FGFR2/GLI1/BMP4 | 10 |
| WP_INFLAMMATORY_RESPONSE_PATHWAY | WP_INFLAMMATORY_RESPONSE_PATHWAY | WP_INFLAMMATORY_RESPONSE_PATHWAY | 10/1438 | 33/23056 | 0.3030303 | 4.858600 | 5.720843 | 0.0000213 | 0.0002118 | 0.0001361 | TNFRSF1B/LAMC2/COL3A1/FN1/LAMB2/TNFRSF1A/THBS1/IL4R/COL1A1/IL2RB | 10 |
| GOBP_REGULATION_OF_T_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_T_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_T_CELL_DIFFERENTIATION | 24/1438 | 151/23056 | 0.1589404 | 2.548352 | 4.923197 | 0.0000215 | 0.0002141 | 0.0001376 | RUNX3/ZC3H12A/PTPRC/ITPKB/NLRP3/CYP26B1/TGFBR2/BCL6/LEF1/IL15/IL7R/VNN1/GLI3/SHH/ANXA1/NCKAP1L/TESPA1/BMP4/IL4R/TNFSF9/IL12RB1/PSG9/IL4I1/RUNX1 | 24 |
| DIRMEIER_LMP1_RESPONSE_EARLY | DIRMEIER_LMP1_RESPONSE_EARLY | DIRMEIER_LMP1_RESPONSE_EARLY | 14/1438 | 62/23056 | 0.2258065 | 3.620441 | 5.328649 | 0.0000217 | 0.0002157 | 0.0001387 | ZC3H12A/ACKR3/TNFAIP3/TRAF1/NFKB2/BIRC3/LCP1/NFKBIA/BCL2A1/JUP/GADD45B/TNFSF9/ICAM1/ZFP36 | 14 |
| HP_ANONYCHIA | HP_ANONYCHIA | HP_ANONYCHIA | 14/1438 | 62/23056 | 0.2258065 | 3.620441 | 5.328649 | 0.0000217 | 0.0002157 | 0.0001387 | KCNN3/LAMC2/LAMB3/ACTG2/ITGA6/COL7A1/DSP/NOTCH1/MMP1/JUP/NOG/ITGB4/SCN1B/GPC4 | 14 |
| KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY | KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY | KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY | 14/1438 | 62/23056 | 0.2258065 | 3.620441 | 5.328649 | 0.0000217 | 0.0002157 | 0.0001387 | NLRP3/IL1B/CASP8/CXCL8/CXCL1/CXCL2/CARD6/TNFAIP3/IL6/TRIP6/BIRC3/CASP1/NFKBIA/CCL5 | 14 |
| MAHAJAN_RESPONSE_TO_IL1A_DN | MAHAJAN_RESPONSE_TO_IL1A_DN | MAHAJAN_RESPONSE_TO_IL1A_DN | 15/1438 | 70/23056 | 0.2142857 | 3.435724 | 5.263804 | 0.0000218 | 0.0002159 | 0.0001388 | EPHA2/MITF/ITGB5/LPP/LAMA4/CCN2/SYNJ2/EPHB4/AKR1B10/POSTN/FOS/CYP19A1/KDELR3/COL4A5/PLS3 | 15 |
| VERRECCHIA_RESPONSE_TO_TGFB1_C2 | VERRECCHIA_RESPONSE_TO_TGFB1_C2 | VERRECCHIA_RESPONSE_TO_TGFB1_C2 | 8/1438 | 21/23056 | 0.3809524 | 6.107954 | 6.039720 | 0.0000220 | 0.0002178 | 0.0001400 | RHOC/COL3A1/FN1/COL6A3/MMP3/MMP14/JUP/ICAM1 | 8 |
| GOBP_POSITIVE_REGULATION_OF_BINDING | GOBP_POSITIVE_REGULATION_OF_BINDING | GOBP_POSITIVE_REGULATION_OF_BINDING | 26/1438 | 171/23056 | 0.1520468 | 2.437824 | 4.867237 | 0.0000222 | 0.0002199 | 0.0001414 | S100A10/EPHA4/PPARG/WNT5A/HES1/EGF/ITGA2/STING1/FOXC1/HFE/CAV1/MET/EBF2/CTHRC1/KLF4/NRP1/TCF7L2/IGF1/BMP4/DACT1/ANXA2/MYOCD/CSF3/TGFB1/APOE/BMP2 | 26 |
| GOBP_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | GOBP_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | GOBP_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE | 12/1438 | 47/23056 | 0.2553191 | 4.093629 | 5.475484 | 0.0000224 | 0.0002214 | 0.0001423 | PTGS2/NLRP3/IL1B/OSMR/HLA-E/IL6/ALOX5AP/EDNRB/CCR7/TNFRSF11A/CREB3L3/C3 | 12 |
| GOBP_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS | GOBP_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS | GOBP_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS | 12/1438 | 47/23056 | 0.2553191 | 4.093629 | 5.475484 | 0.0000224 | 0.0002214 | 0.0001423 | TGFB2/BMP10/TNNC1/HEG1/FOXC1/DSP/ZFPM2/NOTCH1/FGFR2/TPM1/NOG/TGFB1 | 12 |
| MCDOWELL_ACUTE_LUNG_INJURY_UP | MCDOWELL_ACUTE_LUNG_INJURY_UP | MCDOWELL_ACUTE_LUNG_INJURY_UP | 12/1438 | 47/23056 | 0.2553191 | 4.093629 | 5.475484 | 0.0000224 | 0.0002214 | 0.0001423 | CCN1/FCGR2A/LTBP1/COL3A1/SPP1/OSMR/TGFBI/PLA2G7/NFKBIA/FOS/TPM1/ZFP36 | 12 |
| PID_DELTA_NP63_PATHWAY | PID_DELTA_NP63_PATHWAY | PID_DELTA_NP63_PATHWAY | 12/1438 | 47/23056 | 0.2553191 | 4.093629 | 5.475484 | 0.0000224 | 0.0002214 | 0.0001423 | IL1A/HES1/PERP/CEBPD/COL5A1/NOTCH1/RAB38/YAP1/RRAD/ITGA3/AXL/RUNX1 | 12 |
| SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | 12/1438 | 47/23056 | 0.2553191 | 4.093629 | 5.475484 | 0.0000224 | 0.0002214 | 0.0001423 | CXCL8/EREG/CCN2/STC1/ANGPT1/ADM/MMP1/GADD45B/GDF15/HMOX1/SSX1/SPANXA1 | 12 |
| MARTIN_VIRAL_GPCR_SIGNALING_UP | MARTIN_VIRAL_GPCR_SIGNALING_UP | MARTIN_VIRAL_GPCR_SIGNALING_UP | 17/1438 | 87/23056 | 0.1954023 | 3.132959 | 5.140737 | 0.0000228 | 0.0002246 | 0.0001444 | VCAM1/SOD3/CXCL2/SPP1/OSMR/FST/CCDC69/CYP39A1/TRDN/ITGB8/ANXA8L1/C1S/LATS2/FLT1/HOXB7/DSG2/C3 | 17 |
| ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | 17/1438 | 87/23056 | 0.1954023 | 3.132959 | 5.140737 | 0.0000228 | 0.0002246 | 0.0001444 | RUNX3/WNT5A/IL1RAP/HES1/SEL1L3/MYO10/HLA-E/GPSM3/CITED2/CAV2/CAV1/VWA5A/STAT6/FOS/CES1/SIRPA/CEBPB | 17 |
| GOBP_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS | GOBP_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS | GOBP_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS | 9/1438 | 27/23056 | 0.3333333 | 5.344460 | 5.825516 | 0.0000234 | 0.0002294 | 0.0001475 | TNFRSF1B/CCN1/TGFB2/LEF1/FOXC1/NOTCH1/CRYAB/TNFRSF1A/BMP4 | 9 |
| GOBP_EMBRYONIC_PLACENTA_MORPHOGENESIS | GOBP_EMBRYONIC_PLACENTA_MORPHOGENESIS | GOBP_EMBRYONIC_PLACENTA_MORPHOGENESIS | 9/1438 | 27/23056 | 0.3333333 | 5.344460 | 5.825516 | 0.0000234 | 0.0002294 | 0.0001475 | CCN1/LEF1/GCM1/RSPO3/FGFR2/ADM/ZFP36L1/SOCS3/WNT7B | 9 |
| GOBP_RENAL_FILTRATION | GOBP_RENAL_FILTRATION | GOBP_RENAL_FILTRATION | 9/1438 | 27/23056 | 0.3333333 | 5.344460 | 5.825516 | 0.0000234 | 0.0002294 | 0.0001475 | CD34/JCHAIN/F2RL1/ADGRF5/SULF1/MYO1E/ITGA3/PDGFB/TBC1D8B | 9 |
| GOBP_STEROID_CATABOLIC_PROCESS | GOBP_STEROID_CATABOLIC_PROCESS | GOBP_STEROID_CATABOLIC_PROCESS | 9/1438 | 27/23056 | 0.3333333 | 5.344460 | 5.825516 | 0.0000234 | 0.0002294 | 0.0001475 | HSD11B1/SRD5A2/SULT1E1/SPP1/CYP39A1/CYP46A1/CYP19A1/APOE/CYP24A1 | 9 |
| HP_POOR_WOUND_HEALING | HP_POOR_WOUND_HEALING | HP_POOR_WOUND_HEALING | 9/1438 | 27/23056 | 0.3333333 | 5.344460 | 5.825516 | 0.0000234 | 0.0002294 | 0.0001475 | CFH/COL5A2/CFI/COL12A1/SERPINE1/COL5A1/C1R/COL1A1/RAC2 | 9 |
| HP_URINARY_RETENTION | HP_URINARY_RETENTION | HP_URINARY_RETENTION | 9/1438 | 27/23056 | 0.3333333 | 5.344460 | 5.825516 | 0.0000234 | 0.0002294 | 0.0001475 | LAMC2/LAMB3/ACTG2/SP110/SH3TC2/EXT1/STAT6/TGFB1/PRNP | 9 |
| LI_WILMS_TUMOR | LI_WILMS_TUMOR | LI_WILMS_TUMOR | 9/1438 | 27/23056 | 0.3333333 | 5.344460 | 5.825516 | 0.0000234 | 0.0002294 | 0.0001475 | CRABP2/LYPD1/GLI3/HAS2/COL13A1/HMGA2/SIX1/MEOX1/MN1 | 9 |
| GOBP_CALCIUM_ION_TRANSPORT | GOBP_CALCIUM_ION_TRANSPORT | GOBP_CALCIUM_ION_TRANSPORT | 49/1438 | 424/23056 | 0.1155660 | 1.852914 | 4.571735 | 0.0000238 | 0.0002336 | 0.0001502 | MCOLN2/CASQ1/PTGS2/PTPRC/ATP2B4/AGT/TMEM37/TRPM8/MYLK/HES1/EGF/TRPC3/EDN1/ITPR3/TRDN/CCN2/PKD1L1/CAV1/STC1/TRPA1/TMC1/TRPM6/PLPP4/AHNAK/CATSPER1/UBASH3B/CACNA2D4/TPCN1/TRPC4/EDNRB/PRKD1/SLC24A4/BDKRB1/ANXA2/GRAMD2A/ORAI3/RRAD/TRPV2/CCL5/CCR7/HAP1/CACNA1A/KCNN4/CACNG6/PRNP/REM1/JPH2/PDGFB/CYSLTR1 | 49 |
| GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | 19/1438 | 105/23056 | 0.1809524 | 2.901278 | 5.036093 | 0.0000241 | 0.0002362 | 0.0001519 | RUNX3/ZC3H12A/PTPN22/PTPRC/ITPKB/NLRP3/TGFBR2/BCL6/HFE/HLA-E/GLI3/SHH/CD274/ANXA1/NCKAP1L/IL4R/EBI3/IL12RB1/RUNX1 | 19 |
| GOBP_REGULATION_OF_HEART_RATE | GOBP_REGULATION_OF_HEART_RATE | GOBP_REGULATION_OF_HEART_RATE | 19/1438 | 105/23056 | 0.1809524 | 2.901278 | 5.036093 | 0.0000241 | 0.0002362 | 0.0001519 | EDN2/AGT/KCNE4/DSP/EDN1/SEMA3A/CAV1/RNLS/ADM/KCNA5/SPX/EDNRB/TPM1/HCN4/JUP/KCNJ2/DSG2/SCN1B/ADRA1D | 19 |
| GOBP_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE | 27/1438 | 182/23056 | 0.1483516 | 2.378578 | 4.815599 | 0.0000244 | 0.0002387 | 0.0001535 | C1QTNF12/TNFRSF1B/PTPRC/NLRP3/PPARG/PLK2/NT5E/TNFAIP3/TEK/KLF4/ALOX5/NLRP6/SAA1/APOA1/TNFRSF1A/IGF1/LRFN5/CYP19A1/FOXF1/RHBDF2/SOCS3/METRNL/ELANE/ZFP36/APOE/SIRPA/PTGIS | 27 |
| GOBP_NOTCH_SIGNALING_PATHWAY | GOBP_NOTCH_SIGNALING_PATHWAY | GOBP_NOTCH_SIGNALING_PATHWAY | 27/1438 | 182/23056 | 0.1483516 | 2.378578 | 4.815599 | 0.0000244 | 0.0002387 | 0.0001535 | TGFB2/DLX1/DLX2/DNER/TGFBR2/SUSD5/BCL6/HES1/FOXC1/PERP/TCIM/S1PR3/NOTCH1/CFAP58/MAML2/YAP1/KCNA5/POSTN/MMP14/NFKBIA/SIX1/KRT19/SOX9/LLGL2/BMP2/GATA5/MAGEA1 | 27 |
| OKUMURA_INFLAMMATORY_RESPONSE_LPS | OKUMURA_INFLAMMATORY_RESPONSE_LPS | OKUMURA_INFLAMMATORY_RESPONSE_LPS | 27/1438 | 182/23056 | 0.1483516 | 2.378578 | 4.815599 | 0.0000244 | 0.0002387 | 0.0001535 | FCGR2A/NIBAN1/AGT/CXCL8/SLC7A11/FOXC1/RUNX2/PTPRK/TNFAIP3/CITED2/TNS3/CEBPD/CA1/FZD6/ZFPM2/WT1/RAB38/BIRC3/THBS1/CA12/CCL5/CCR7/IL27RA/RELB/SDC4/RUNX1/CHST7 | 27 |
| MANNE_COVID19_ICU_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_ICU_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_ICU_VS_HEALTHY_DONOR_PLATELETS_DN | 25/1438 | 162/23056 | 0.1543210 | 2.474287 | 4.856607 | 0.0000245 | 0.0002392 | 0.0001538 | TNFSF18/CD34/TGFB2/WNT9A/CAVIN2/ACKR2/KDR/CXCL5/IL7R/TGFBI/CLIC5/TNFRSF21/UTRN/SASH1/SCIN/PDCD1LG2/PAPPA/MYEOV/YAP1/ALDH1A2/CAVIN1/SMIM36/APCDD1L/MAP3K7CL/LGALS2 | 25 |
| REACTOME_SIGNALING_BY_MET | REACTOME_SIGNALING_BY_MET | REACTOME_SIGNALING_BY_MET | 16/1438 | 79/23056 | 0.2025316 | 3.247267 | 5.160310 | 0.0000247 | 0.0002409 | 0.0001549 | LAMC2/LAMB3/COL3A1/COL5A2/FN1/LAMB2/ITGA2/LAMA4/LAMA2/TNS3/MET/COL27A1/COL5A1/PTPRJ/ITGA3/COL1A1 | 16 |
| ELVIDGE_HYPOXIA_BY_DMOG_UP | ELVIDGE_HYPOXIA_BY_DMOG_UP | ELVIDGE_HYPOXIA_BY_DMOG_UP | 22/1438 | 133/23056 | 0.1654135 | 2.652138 | 4.928227 | 0.0000248 | 0.0002418 | 0.0001554 | S100A2/ELF3/BHLHE40/PLAC8/VEGFC/TGFBI/GJA1/CITED2/SERPINE1/CAV1/MET/CSGALNACT1/LOXL2/STC1/ASPH/ADM/GPRC5A/FOS/AHNAK2/SOX9/GDF15/SAT1 | 22 |
| GOBP_ACTIN_FILAMENT_BASED_MOVEMENT | GOBP_ACTIN_FILAMENT_BASED_MOVEMENT | GOBP_ACTIN_FILAMENT_BASED_MOVEMENT | 22/1438 | 133/23056 | 0.1654135 | 2.652138 | 4.928227 | 0.0000248 | 0.0002418 | 0.0001554 | KCNE4/TNNC1/DSP/GJA1/WIPF3/CAV1/STC1/GSN/KCNA5/FRMD6/ACTC1/MYO1E/TPM1/HCN4/MYH8/MYH4/MYH2/JUP/KCNJ2/DSG2/SCN1B/MYH9 | 22 |
| GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_ASSEMBLY | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_ASSEMBLY | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_ASSEMBLY | 7/1438 | 16/23056 | 0.4375000 | 7.014604 | 6.206975 | 0.0000251 | 0.0002441 | 0.0001569 | TIE1/AGT/PHLDB2/HAS2/NOTCH1/SOX9/TGFB1 | 7 |
| GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS_OXYGEN_AS_ACCEPTOR | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS_OXYGEN_AS_ACCEPTOR | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS_OXYGEN_AS_ACCEPTOR | 7/1438 | 16/23056 | 0.4375000 | 7.014604 | 6.206975 | 0.0000251 | 0.0002441 | 0.0001569 | VCAM1/DDO/LOXL2/RNLS/LOXL4/LOXL1/IL4I1 | 7 |
| LEE_LIVER_CANCER_HEPATOBLAST | LEE_LIVER_CANCER_HEPATOBLAST | LEE_LIVER_CANCER_HEPATOBLAST | 7/1438 | 16/23056 | 0.4375000 | 7.014604 | 6.206975 | 0.0000251 | 0.0002441 | 0.0001569 | PTGS2/IL6/CD44/MMP1/KRT7/FOS/KRT19 | 7 |
| GOBP_HEART_VALVE_MORPHOGENESIS | GOBP_HEART_VALVE_MORPHOGENESIS | GOBP_HEART_VALVE_MORPHOGENESIS | 13/1438 | 55/23056 | 0.2363636 | 3.789708 | 5.342210 | 0.0000253 | 0.0002454 | 0.0001578 | TIE1/CCN1/TGFB2/TGFBR2/FGFRL1/SLIT2/NOTCH1/BMP4/SMAD6/SOX9/TGFB1/BMP2/GATA5 | 13 |
| GOBP_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | GOBP_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | GOBP_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 29/1438 | 203/23056 | 0.1428571 | 2.290483 | 4.763025 | 0.0000257 | 0.0002492 | 0.0001602 | ZC3H12A/PTPN22/TGFB2/IL1A/IL1B/WNT5A/TLR3/F2RL1/SH3RF2/TPD52L1/CCN2/SASH1/SEMA3A/MDFIC/GDF6/TRAF1/FAS/IGFBP6/TNFRSF19/FOXO1/BMP4/DACT1/CCR7/GADD45B/SIRPA/BMP2/BIRC7/WNT7B/MID1 | 29 |
| REACTOME_INTERFERON_SIGNALING | REACTOME_INTERFERON_SIGNALING | REACTOME_INTERFERON_SIGNALING | 29/1438 | 203/23056 | 0.1428571 | 2.290483 | 4.763025 | 0.0000257 | 0.0002492 | 0.0001602 | GBP3/GBP1/GBP2/GBP4/GBP5/VCAM1/RNASEL/TRIM17/SP100/UBA7/TRIM38/HLA-E/HLA-C/PSMB8/DDX58/IFITM2/IFITM3/TRIM5/CD44/OASL/IRF9/MT2A/IFI35/SOCS3/ICAM1/MX2/MX1/USP18/MID1 | 29 |
| HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_2NM_UP | 15/1438 | 71/23056 | 0.2112676 | 3.387334 | 5.196062 | 0.0000260 | 0.0002521 | 0.0001621 | PDZK1IP1/IFI16/AGT/NPAS2/IL1RAP/IQGAP2/THBS2/PTPN3/PRSS23/ARHGDIB/LCP1/MAF/HOXB2/THBD/HMOX1 | 15 |
| REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | REACTOME_GLYCOSAMINOGLYCAN_METABOLISM | 21/1438 | 124/23056 | 0.1693548 | 2.715330 | 4.939602 | 0.0000262 | 0.0002536 | 0.0001630 | AGRN/HSPG2/PRELP/CHSY3/UST/CSGALNACT1/EXT1/HAS2/ST3GAL1/B4GALT1/PAPSS2/CD44/LUM/CSPG4/HS3ST3A1/B3GNT3/HAS1/SDC4/CHST7/GPC4/BGN | 21 |
| GOBP_POSITIVE_REGULATION_OF_SECRETION | GOBP_POSITIVE_REGULATION_OF_SECRETION | GOBP_POSITIVE_REGULATION_OF_SECRETION | 38/1438 | 300/23056 | 0.1266667 | 2.030895 | 4.635336 | 0.0000263 | 0.0002544 | 0.0001636 | C1QTNF12/PLA2G4A/TGFB2/AGT/IL1A/IL1B/PPARG/FOXL2/SPP1/VEGFC/GDNF/DAB2/F2RL1/PCSK1/BMP6/EDN1/HFE/SCIN/AQP1/INHBA/CADPS2/ADAM9/ADCY8/ANKRD1/TCF7L2/P2RY2/IGF1/EDNRB/CYP19A1/IL4R/GIP/C1QTNF1/MYOM1/TNFRSF11A/TGFB1/KCNN4/BMP2/SDC4 | 38 |
| GOBP_SYNCYTIUM_FORMATION | GOBP_SYNCYTIUM_FORMATION | GOBP_SYNCYTIUM_FORMATION | 14/1438 | 63/23056 | 0.2222222 | 3.562973 | 5.253767 | 0.0000263 | 0.0002544 | 0.0001636 | CD53/GCM1/CD109/ADAM9/MYOF/ADAMTS15/CYP19A1/IL4R/TNFSF14/GDF15/EHD2/NFATC2/ADAMTS5/MYH9 | 14 |
| SANSOM_WNT_PATHWAY_REQUIRE_MYC | SANSOM_WNT_PATHWAY_REQUIRE_MYC | SANSOM_WNT_PATHWAY_REQUIRE_MYC | 14/1438 | 63/23056 | 0.2222222 | 3.562973 | 5.253767 | 0.0000263 | 0.0002544 | 0.0001636 | PTGS2/LEF1/LECT2/EDN1/SEMA3C/PLAT/FZD6/CCN4/CD44/TNFRSF19/MMP14/TNFRSF12A/SOX9/SIM2 | 14 |
| WP_TYROBP_CAUSAL_NETWORK_IN_MICROGLIA | WP_TYROBP_CAUSAL_NETWORK_IN_MICROGLIA | WP_TYROBP_CAUSAL_NETWORK_IN_MICROGLIA | 14/1438 | 63/23056 | 0.2222222 | 3.562973 | 5.253767 | 0.0000263 | 0.0002544 | 0.0001636 | TNFRSF1B/RUNX3/CAPG/RBM47/SPP1/GIMAP2/APBB1IP/NCKAP1L/SLC7A7/MAF/ADAP2/C3/CD37/IL13RA1 | 14 |
| GENTILE_UV_HIGH_DOSE_DN | GENTILE_UV_HIGH_DOSE_DN | GENTILE_UV_HIGH_DOSE_DN | 37/1438 | 289/23056 | 0.1280277 | 2.052716 | 4.644743 | 0.0000264 | 0.0002551 | 0.0001640 | CCN1/PRRX1/DLX2/ITGA6/CASP8/BHLHE40/TM4SF1/FGF5/VEGFC/FOXD1/HBEGF/PXDC1/CCN2/TNFAIP3/MET/PODXL/CEBPD/ASPH/HAS2/GAS1/DKK1/COL13A1/MMP3/TNFRSF1A/EPS8/HMGA2/NAV3/THBS1/IL4R/NUPR1/RRAD/HOXB2/FSTL3/ZFP36/IL11/RUNX1/SAT1 | 37 |
| GOBP_BONE_REMODELING | GOBP_BONE_REMODELING | GOBP_BONE_REMODELING | 17/1438 | 88/23056 | 0.1931818 | 3.097357 | 5.084011 | 0.0000266 | 0.0002567 | 0.0001650 | EPHA2/S1PR1/MITF/SPP1/ADRB2/GJA1/TNFAIP3/IL6/PDK4/PTN/CTHRC1/EXT1/TNFRSF11B/UBASH3B/SIGLEC15/TNFRSF11A/TGFB1 | 17 |
| GOBP_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | GOBP_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | GOBP_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 24/1438 | 153/23056 | 0.1568627 | 2.515040 | 4.849287 | 0.0000269 | 0.0002590 | 0.0001665 | PTPRC/AGT/IL1A/IL1B/ITGA6/SP100/GDNF/CSF2/TNFAIP3/INHBA/SERPINE1/CAV1/TRAF1/NRP1/ITPRIP/TCF7L2/YAP1/IGF1/BMP4/THBS1/TNFRSF12A/TMC8/ICAM1/HMOX1 | 24 |
| HP_ABNORMAL_ELASTICITY_OF_SKIN | HP_ABNORMAL_ELASTICITY_OF_SKIN | HP_ABNORMAL_ELASTICITY_OF_SKIN | 30/1438 | 214/23056 | 0.1401869 | 2.247670 | 4.729267 | 0.0000271 | 0.0002611 | 0.0001678 | TBX15/KCNN3/TGFB2/COL3A1/COL5A2/TWIST2/TGFBR2/CD96/FGFR3/OSMR/SPARC/ADAMTS2/FOXC1/COL12A1/TENT5A/TMEM270/FGF20/TRPS1/EXT1/GSN/COL5A1/FGFR2/EFEMP2/C1S/C1R/SLC7A7/FBLN5/FBN1/COL1A1/RIN2 | 30 |
| GOBP_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | GOBP_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | GOBP_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS | 41/1438 | 334/23056 | 0.1227545 | 1.968169 | 4.596799 | 0.0000271 | 0.0002611 | 0.0001678 | ERRFI1/ZC3H12A/PTGS2/MYLK/SOD3/SLC7A11/EDN1/PTPRK/VNN1/TNFAIP3/SOD2/IL6/AQP1/CD36/FZD1/CAV1/MET/GPR37/TRPA1/ANXA1/AKR1C3/ALOX5/AIFM2/FAS/ALDH3B1/MMP3/YBX3/STAT6/FOXO1/PRKD1/ZFP36L1/FOS/FBLN5/TPM1/MMP2/NQO1/KLF2/AXL/RELB/SIRPA/HMOX1 | 41 |
| GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 25/1438 | 163/23056 | 0.1533742 | 2.459107 | 4.821520 | 0.0000273 | 0.0002620 | 0.0001684 | RUNX3/TGFB2/PPARG/WNT5A/EREG/DAB2/SPARC/CD109/PTPRK/CAV2/CAV1/SULF1/EPPK1/ALOX5/MMRN2/FGFR2/WNT10B/KRT4/FLT1/BMP4/THBS1/NUPR1/SOX9/TGFB1/APOE | 25 |
| MIKKELSEN_MCV6_LCP_WITH_H3K4ME3 | MIKKELSEN_MCV6_LCP_WITH_H3K4ME3 | MIKKELSEN_MCV6_LCP_WITH_H3K4ME3 | 25/1438 | 163/23056 | 0.1533742 | 2.459107 | 4.821520 | 0.0000273 | 0.0002620 | 0.0001684 | PDZK1IP1/GBP2/GPA33/MR1/CFH/PRELP/IKBKE/IL17RC/GALNT15/BTC/IL7R/GPSM3/ANXA1/ALDH3B1/VWA5A/ROBO4/C1RL/ARHGDIB/TNS2/MSLN/CSF3/IFI35/SERPINB8/KCNN4/EMP3 | 25 |
| CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | 26/1438 | 173/23056 | 0.1502890 | 2.409641 | 4.799868 | 0.0000273 | 0.0002620 | 0.0001684 | GFI1/ATP2B4/STAB1/CD96/FNDC3B/HBEGF/TPBG/CITED2/CEBPD/ANXA8/TCF7L2/PTPRE/NRIP3/CD44/PLAAT3/KRT18/GLIPR1/FLT3/NFKBIA/FOS/MRC2/KLF2/ZFP36/COL4A5/GABRE/ZNF185 | 26 |
| GOBP_FACE_DEVELOPMENT | GOBP_FACE_DEVELOPMENT | GOBP_FACE_DEVELOPMENT | 12/1438 | 48/23056 | 0.2500000 | 4.008345 | 5.381001 | 0.0000282 | 0.0002704 | 0.0001738 | WNT5A/LEF1/ASPH/DKK1/ALDH1A2/ALDH1A3/MMP2/CRISPLD2/HOXB3/COL1A1/NOG/RRAS | 12 |
| GOBP_KERATINOCYTE_PROLIFERATION | GOBP_KERATINOCYTE_PROLIFERATION | GOBP_KERATINOCYTE_PROLIFERATION | 12/1438 | 48/23056 | 0.2500000 | 4.008345 | 5.381001 | 0.0000282 | 0.0002704 | 0.0001738 | EREG/FST/CD109/PTPRK/HAS2/EPPK1/FGFR2/YAP1/PRKD1/ZFP36L1/CDH13/ZFP36 | 12 |
| GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL | 12/1438 | 48/23056 | 0.2500000 | 4.008345 | 5.381001 | 0.0000282 | 0.0002704 | 0.0001738 | ECE1/EDN2/AGT/SUCNR1/F2RL1/ADRB2/EDN1/SOD2/PCSK5/EDNRB/TPM1/ADRA1D | 12 |
| GOBP_DEVELOPMENTAL_INDUCTION | GOBP_DEVELOPMENTAL_INDUCTION | GOBP_DEVELOPMENTAL_INDUCTION | 10/1438 | 34/23056 | 0.2941176 | 4.715700 | 5.591944 | 0.0000284 | 0.0002720 | 0.0001749 | WNT5A/GDNF/DKK1/BMP4/SIX1/SOX8/SALL1/SOX9/BMP2/GATA5 | 10 |
| GOMF_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | GOMF_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | GOMF_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | 10/1438 | 34/23056 | 0.2941176 | 4.715700 | 5.591944 | 0.0000284 | 0.0002720 | 0.0001749 | GALNT5/GALNT3/GALNT15/GALNTL6/CHSY3/GALNT10/GALNT17/CSGALNACT1/GALNT18/GALNT9 | 10 |
| GROSS_HYPOXIA_VIA_ELK3_ONLY_UP | GROSS_HYPOXIA_VIA_ELK3_ONLY_UP | GROSS_HYPOXIA_VIA_ELK3_ONLY_UP | 10/1438 | 34/23056 | 0.2941176 | 4.715700 | 5.591944 | 0.0000284 | 0.0002720 | 0.0001749 | AMOTL2/CXCL6/CXCL3/SLC7A11/FST/IL6/ADM/LCP1/THBD/CEBPB | 10 |
| YAGI_AML_FAB_MARKERS | YAGI_AML_FAB_MARKERS | YAGI_AML_FAB_MARKERS | 28/1438 | 194/23056 | 0.1443299 | 2.314096 | 4.740511 | 0.0000291 | 0.0002778 | 0.0001786 | TNFRSF4/TNFRSF1B/S100A10/CFH/NLRP3/CAPG/ITGA6/SERPINE2/FGFR3/ADAMTS3/ELL2/RHAG/CAV1/VCL/AHNAK/SERPINH1/CASP1/CPM/LCP1/TNFAIP2/ANXA2/TPM1/CD68/MYL4/TGM2/DOK5/LGALS1/GABRE | 28 |
| GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_DN | 16/1438 | 80/23056 | 0.2000000 | 3.206676 | 5.099183 | 0.0000291 | 0.0002778 | 0.0001786 | GBP1/LYPD1/ACKR3/GXYLT2/PHLDB2/SMIM3/FOXC1/TFAP2A/TBX18/TCIM/HRCT1/SPAAR/FZD8/PPP1R3C/LIPG/PDGFB | 16 |
| GOBP_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | GOBP_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | GOBP_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | 16/1438 | 80/23056 | 0.2000000 | 3.206676 | 5.099183 | 0.0000291 | 0.0002778 | 0.0001786 | IL1B/GALNT5/EGF/CHSY3/UST/CSGALNACT1/ANGPT1/EXT1/HAS2/ST3GAL1/HS3ST3A1/B3GNT3/TGFB1/HAS1/PDGFB/CHST7 | 16 |
| GAL_LEUKEMIC_STEM_CELL_DN | GAL_LEUKEMIC_STEM_CELL_DN | GAL_LEUKEMIC_STEM_CELL_DN | 32/1438 | 236/23056 | 0.1355932 | 2.174018 | 4.675489 | 0.0000292 | 0.0002788 | 0.0001792 | FCGR2A/CAPG/IL1B/HNMT/DES/ALDH1L1/CXCL1/LAMA4/STX11/CEBPD/MS4A4A/SLC15A3/CASP1/SCNN1A/C3AR1/NPAS3/SERPINA1/CA12/RRAD/ADAP2/CCL5/DLX4/MRC2/ELANE/KLK6/FPR1/SIRPA/COL18A1/COL6A2/IL2RB/LGALS2/LGALS1 | 32 |
| HP_HETEROGENEOUS | HP_HETEROGENEOUS | HP_HETEROGENEOUS | 32/1438 | 236/23056 | 0.1355932 | 2.174018 | 4.675489 | 0.0000292 | 0.0002788 | 0.0001792 | PTCH2/PTPN22/LAMC2/LAMB3/CASP8/MLPH/MITF/ENAM/SH3TC2/FOXC1/DSP/HFE/ITPR3/IL6/MET/PDGFRL/GDF6/TPM2/PLAU/SLC22A18/WT1/EDNRB/SIX1/FBLN5/KRT17/ITGB4/DSG2/TNFRSF11A/CACNA1A/MID1/COL4A5/GPC4 | 32 |
| GOBP_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_LEUKOCYTE_MEDIATED_IMMUNITY | 51/1438 | 451/23056 | 0.1130820 | 1.813087 | 4.497565 | 0.0000294 | 0.0002801 | 0.0001801 | TNFRSF1B/S100A13/MR1/PTPRC/NLRP3/IL1R1/IL1B/CD96/BCL6/SPON2/CXCL6/ANXA3/CFI/TLR3/IL7R/C9/F2RL1/HFE/HLA-E/MICA/RAET1E/AHR/IL6/CLU/DDX58/MBL2/NLRP6/C1S/C1R/C1RL/KLRD1/KLRC4-KLRK1/NCKAP1L/STAT6/IL4R/IL21R/LAT/FOXF1/MILR1/ELANE/CD70/C3/ICAM1/IL27RA/IL12RB1/TGFB1/BCL3/NECTIN2/IL4I1/HMOX1/RAC2 | 51 |
| BLANCO_MELO_INFLUENZA_A_INFECTION_A594_CELLS_UP | BLANCO_MELO_INFLUENZA_A_INFECTION_A594_CELLS_UP | BLANCO_MELO_INFLUENZA_A_INFECTION_A594_CELLS_UP | 11/1438 | 41/23056 | 0.2682927 | 4.301639 | 5.457204 | 0.0000297 | 0.0002821 | 0.0001814 | CXCL8/CXCL5/EREG/HBEGF/CCN2/STC1/ANKRD1/PYGM/CPM/CCL5/DHX58 | 11 |
| REACTOME_DISEASES_ASSOCIATED_WITH_GLYCOSAMINOGLYCAN_METABOLISM | REACTOME_DISEASES_ASSOCIATED_WITH_GLYCOSAMINOGLYCAN_METABOLISM | REACTOME_DISEASES_ASSOCIATED_WITH_GLYCOSAMINOGLYCAN_METABOLISM | 11/1438 | 41/23056 | 0.2682927 | 4.301639 | 5.457204 | 0.0000297 | 0.0002821 | 0.0001814 | AGRN/HSPG2/PRELP/EXT1/B4GALT1/PAPSS2/LUM/CSPG4/SDC4/GPC4/BGN | 11 |
| BLANCO_MELO_COVID19_SARS_COV_2_LOW_MOI_INFECTION_A594_ACE2_EXPRESSING_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_LOW_MOI_INFECTION_A594_ACE2_EXPRESSING_CELLS_UP | BLANCO_MELO_COVID19_SARS_COV_2_LOW_MOI_INFECTION_A594_ACE2_EXPRESSING_CELLS_UP | 26/1438 | 174/23056 | 0.1494253 | 2.395792 | 4.766534 | 0.0000302 | 0.0002871 | 0.0001845 | ZC3H12A/PRG4/PTGS2/IL1A/DLX2/C2orf66/CXCL8/CXCL1/CXCL3/CXCL2/EREG/FST/FGF18/IER3/TNFAIP3/TCERG1L/C1R/BHLHE41/NFKBIA/SIX4/FOS/CSF3/SOCS3/ICAM1/ZFP36/BCL3 | 26 |
| GOBP_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 35/1438 | 269/23056 | 0.1301115 | 2.086127 | 4.621337 | 0.0000307 | 0.0002919 | 0.0001876 | AGRN/TNFRSF1B/CRABP2/IL1B/FN1/EPHA4/SERPINE2/MME/IL1RAP/HES1/SLIT2/GRID2/VEGFC/SEMA5A/TPBG/THBS2/IL6/GLI3/PTPRZ1/PTN/SHH/PLAG1/NOTCH1/NRP1/AMIGO2/SOX8/TRPV2/HAP1/MAG/TGFB1/BMP2/TGM2/LIF/SRPX2/SLITRK4 | 35 |
| GOBP_EPIDERMAL_CELL_DIFFERENTIATION | GOBP_EPIDERMAL_CELL_DIFFERENTIATION | GOBP_EPIDERMAL_CELL_DIFFERENTIATION | 29/1438 | 205/23056 | 0.1414634 | 2.268137 | 4.703754 | 0.0000309 | 0.0002932 | 0.0001885 | ERRFI1/EPHA2/PTCH2/TCHH/SPRR2F/CYP26B1/IL1A/WNT5A/HES1/EREG/FOXC1/DSP/CD109/HOXA7/ADAM9/AQP3/TMC1/ANXA1/KLF4/NOTCH1/AKR1C3/PLAAT4/YAP1/GLI1/BMP4/ZFP36L1/KRT17/GATA6/ZFP36 | 29 |
| RICKMAN_HEAD_AND_NECK_CANCER_C | RICKMAN_HEAD_AND_NECK_CANCER_C | RICKMAN_HEAD_AND_NECK_CANCER_C | 20/1438 | 116/23056 | 0.1724138 | 2.764376 | 4.913349 | 0.0000309 | 0.0002932 | 0.0001885 | CDA/TCHH/PTGS2/IL36G/GPR39/ARL14/EREG/TDO2/VEGFC/ERAP2/ADGRF4/SOD2/FABP4/DKK1/HMGA2/PAQR5/RRAD/SERPINB7/KLK6/COL4A6 | 20 |
| GOBP_POSITIVE_REGULATION_OF_CELL_DIVISION | GOBP_POSITIVE_REGULATION_OF_CELL_DIVISION | GOBP_POSITIVE_REGULATION_OF_CELL_DIVISION | 17/1438 | 89/23056 | 0.1910112 | 3.062556 | 5.028087 | 0.0000310 | 0.0002932 | 0.0001885 | TGFB2/LBH/TGFA/IL1A/IL1B/EREG/BTC/FGF5/PDGFC/VEGFC/PDGFA/MACC1/PTN/SHH/FGFR2/TGFB1/PDGFB | 17 |
| NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | 17/1438 | 89/23056 | 0.1910112 | 3.062556 | 5.028087 | 0.0000310 | 0.0002932 | 0.0001885 | NRP2/FGFR3/LEF1/FOXD1/TPBG/INHBA/FZD1/TRPS1/CCN4/MICAL2/HMGA2/AHNAK2/HS3ST3A1/SLC16A3/COL9A3/SSX1/SSX2 | 17 |
| GOBP_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | GOBP_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | GOBP_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | 13/1438 | 56/23056 | 0.2321429 | 3.722035 | 5.259906 | 0.0000310 | 0.0002932 | 0.0001885 | TGFB2/BMP10/TNNC1/HEG1/FOXC1/DSP/ZFPM2/NOTCH1/FGFR2/TPM1/NOG/DSG2/TGFB1 | 13 |
| GOCC_MYOSIN_COMPLEX | GOCC_MYOSIN_COMPLEX | GOCC_MYOSIN_COMPLEX | 13/1438 | 56/23056 | 0.2321429 | 3.722035 | 5.259906 | 0.0000310 | 0.0002932 | 0.0001885 | MYO10/MYL7/BMF/CGNL1/MYO1E/MYH13/MYH8/MYH4/MYH1/MYH2/MYL4/MYL9/MYH9 | 13 |
| KEGG_HEDGEHOG_SIGNALING_PATHWAY | KEGG_HEDGEHOG_SIGNALING_PATHWAY | KEGG_HEDGEHOG_SIGNALING_PATHWAY | 13/1438 | 56/23056 | 0.2321429 | 3.722035 | 5.259906 | 0.0000310 | 0.0002932 | 0.0001885 | PTCH2/WNT9A/WNT5A/BMP6/GLI3/SHH/GAS1/WNT10B/GLI1/ZIC2/BMP4/BMP2/WNT7B | 13 |
| LEE_LIVER_CANCER_MYC_E2F1_UP | LEE_LIVER_CANCER_MYC_E2F1_UP | LEE_LIVER_CANCER_MYC_E2F1_UP | 13/1438 | 56/23056 | 0.2321429 | 3.722035 | 5.259906 | 0.0000310 | 0.0002932 | 0.0001885 | CTSS/FMO3/SPP1/SPARC/CYP39A1/PLAT/FABP4/KRT8/ANXA2/BCL2A1/COL1A1/ICAM1/USP18 | 13 |
| TAVAZOIE_METASTASIS | TAVAZOIE_METASTASIS | TAVAZOIE_METASTASIS | 19/1438 | 107/23056 | 0.1775701 | 2.847049 | 4.939041 | 0.0000317 | 0.0002996 | 0.0001926 | PTGS2/SULT1C2/KYNU/EREG/HAPLN1/LAMA4/STX11/HOXA7/TSPAN12/VCL/MMP1/CSF3/COL1A1/MYOM1/SERPINB2/SSX1/SSX2/SPANXB1/SPANXA1 | 19 |
| GENTILE_UV_LOW_DOSE_DN | GENTILE_UV_LOW_DOSE_DN | GENTILE_UV_LOW_DOSE_DN | 14/1438 | 64/23056 | 0.2187500 | 3.507302 | 5.180390 | 0.0000318 | 0.0003000 | 0.0001928 | SLIT2/VEGFC/SEMA5A/MYO10/PTPRK/UTRN/SEMA3C/PODXL/ANGPT1/EXT1/COL13A1/MICAL2/HMGA2/NAV3 | 14 |
| GOBP_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 28/1438 | 195/23056 | 0.1435897 | 2.302229 | 4.709895 | 0.0000320 | 0.0003016 | 0.0001939 | RHOC/S100A10/LMOD1/BMP10/SEMA5A/F2RL1/EDN1/CCN2/SCIN/CCL26/MET/LMOD2/ARHGEF5/TEK/GSN/NRP1/SYNPO2L/APOA1/NCKAP1L/NAV3/TPM1/MYLK3/CSF3/CCR7/CDC42EP5/SDC4/CDC42EP1/TENM1 | 28 |
| CHUANG_OXIDATIVE_STRESS_RESPONSE_UP | CHUANG_OXIDATIVE_STRESS_RESPONSE_UP | CHUANG_OXIDATIVE_STRESS_RESPONSE_UP | 9/1438 | 28/23056 | 0.3214286 | 5.153586 | 5.671898 | 0.0000326 | 0.0003058 | 0.0001966 | EDN1/DKK1/FAS/EPS8L2/MT1X/NQO1/GDF15/LIF/HMOX1 | 9 |
| HP_STENOSIS_OF_THE_EXTERNAL_AUDITORY_CANAL | HP_STENOSIS_OF_THE_EXTERNAL_AUDITORY_CANAL | HP_STENOSIS_OF_THE_EXTERNAL_AUDITORY_CANAL | 9/1438 | 28/23056 | 0.3214286 | 5.153586 | 5.671898 | 0.0000326 | 0.0003058 | 0.0001966 | TBX15/COL7A1/FGFRL1/EDN1/HOXA2/FGFR2/SIX1/MAF/SIX5 | 9 |
| GOBP_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 8/1438 | 22/23056 | 0.3636364 | 5.830320 | 5.845973 | 0.0000326 | 0.0003058 | 0.0001966 | OSR1/PDGFA/SHH/WT1/BMP4/SERPINB7/BMP2/PDGFB | 8 |
| GOBP_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | 8/1438 | 22/23056 | 0.3636364 | 5.830320 | 5.845973 | 0.0000326 | 0.0003058 | 0.0001966 | WNT9A/EFEMP1/RARB/NKX3-2/ADAMTS12/CCN4/BMP4/SOX9 | 8 |
| GOCC_MYOSIN_FILAMENT | GOCC_MYOSIN_FILAMENT | GOCC_MYOSIN_FILAMENT | 8/1438 | 22/23056 | 0.3636364 | 5.830320 | 5.845973 | 0.0000326 | 0.0003058 | 0.0001966 | ACTG2/MYH13/MYH8/MYH4/MYH1/MYH2/MYOM1/MYH9 | 8 |
| GOCC_MYOSIN_II_COMPLEX | GOCC_MYOSIN_II_COMPLEX | GOCC_MYOSIN_II_COMPLEX | 8/1438 | 22/23056 | 0.3636364 | 5.830320 | 5.845973 | 0.0000326 | 0.0003058 | 0.0001966 | MYH13/MYH8/MYH4/MYH1/MYH2/MYL4/MYL9/MYH9 | 8 |
| GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT_CONFERRING_COMPRESSION_RESISTANCE | GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT_CONFERRING_COMPRESSION_RESISTANCE | GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT_CONFERRING_COMPRESSION_RESISTANCE | 8/1438 | 22/23056 | 0.3636364 | 5.830320 | 5.845973 | 0.0000326 | 0.0003058 | 0.0001966 | HSPG2/PODN/PRG4/PRELP/ENAM/HAPLN1/LUM/BGN | 8 |
| WP_FGF23_SIGNALING_IN_HYPOPHOSPHATEMIC_RICKETS_AND_RELATED_DISORDERS | WP_FGF23_SIGNALING_IN_HYPOPHOSPHATEMIC_RICKETS_AND_RELATED_DISORDERS | WP_FGF23_SIGNALING_IN_HYPOPHOSPHATEMIC_RICKETS_AND_RELATED_DISORDERS | 8/1438 | 22/23056 | 0.3636364 | 5.830320 | 5.845973 | 0.0000326 | 0.0003058 | 0.0001966 | GALNT3/FGFR3/SPP1/ROS1/FAM20C/NFKB2/FGFR2/CYP24A1 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 23/1438 | 145/23056 | 0.1586207 | 2.543226 | 4.807792 | 0.0000327 | 0.0003065 | 0.0001971 | IL1B/DLX1/DLX2/SEMA3B/WNT5A/HES1/SPP1/SEMA5A/ID4/IL6/SEMA3C/SEMA3A/SEMA3D/PTN/NOTCH1/NRP1/DKK1/PITX3/NFATC4/NOG/MBP/SEMA6B/MAG | 23 |
| GOBP_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | 24/1438 | 155/23056 | 0.1548387 | 2.482588 | 4.776539 | 0.0000334 | 0.0003128 | 0.0002011 | BMP10/CYP26B1/EREG/PRDM6/EDN1/RBM24/SOD2/SHH/NOTCH1/DKK1/FGFR2/EFEMP2/BHLHE41/IGF1/MMP14/BMP4/RBPMS2/MYLK3/PIEZO1/MYOCD/TGFB1/BMP2/NFATC2/PDGFB | 24 |
| SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN | 43/1438 | 360/23056 | 0.1194444 | 1.915098 | 4.513345 | 0.0000338 | 0.0003164 | 0.0002034 | PDZK1IP1/PIFO/ELF3/DAW1/DNER/IQCA1/TMEM40/MUC13/ALDH1L1/MGLL/CXCL1/CFAP299/DNAH5/CCNO/ATP10B/RBM24/TNFRSF21/PRR15/C7orf57/ERICH5/EPPK1/AQP3/PTGR1/CLIC3/AKR1C3/FANK1/SAA1/ALDH3B1/PRSS23/VWA5A/KRT7/KRT4/FAM216B/AHNAK2/CES1/RRAD/NQO1/CLDN7/SLC16A5/SERPINB7/MUC16/CLIC6/BACE2 | 43 |
| GOBP_ENDOCARDIAL_CUSHION_DEVELOPMENT | GOBP_ENDOCARDIAL_CUSHION_DEVELOPMENT | GOBP_ENDOCARDIAL_CUSHION_DEVELOPMENT | 12/1438 | 49/23056 | 0.2448980 | 3.926542 | 5.289042 | 0.0000352 | 0.0003285 | 0.0002112 | TGFB2/TGFBR2/RBM24/CITED2/NOTCH1/BMP4/FOXF1/NOG/SOX9/TGFB1/BMP2/GATA5 | 12 |
| GOBP_ENDOCRINE_HORMONE_SECRETION | GOBP_ENDOCRINE_HORMONE_SECRETION | GOBP_ENDOCRINE_HORMONE_SECRETION | 12/1438 | 49/23056 | 0.2448980 | 3.926542 | 5.289042 | 0.0000352 | 0.0003285 | 0.0002112 | AGT/IL1B/PPARG/FOXL2/DAB2/FOXD1/CRHBP/BMP6/GJA1/INHBA/FZD4/C1QTNF1 | 12 |
| GOBP_NEURON_RECOGNITION | GOBP_NEURON_RECOGNITION | GOBP_NEURON_RECOGNITION | 12/1438 | 49/23056 | 0.2448980 | 3.926542 | 5.289042 | 0.0000352 | 0.0003285 | 0.0002112 | NEXN/EPHA4/EPHA3/SEMA5A/TNFRSF21/SEMA3A/EXT1/NRP1/MYPN/ROBO4/OPCML/NCAM2 | 12 |
| GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION | 12/1438 | 49/23056 | 0.2448980 | 3.926542 | 5.289042 | 0.0000352 | 0.0003285 | 0.0002112 | BMP10/TGFBR2/CITED2/FGF20/ZFPM2/NOTCH1/FGFR2/YAP1/GLI1/NOG/GATA6/RUNX1 | 12 |
| LINDSTEDT_DENDRITIC_CELL_MATURATION_B | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | LINDSTEDT_DENDRITIC_CELL_MATURATION_B | 12/1438 | 49/23056 | 0.2448980 | 3.926542 | 5.289042 | 0.0000352 | 0.0003285 | 0.0002112 | TNFRSF9/TNFAIP3/PDGFA/TRAF1/IL15RA/NFKB2/ADM/BIRC3/NFKBIA/TNFAIP2/RELB/SDC4 | 12 |
| PID_ARF6_TRAFFICKING_PATHWAY | PID_ARF6_TRAFFICKING_PATHWAY | PID_ARF6_TRAFFICKING_PATHWAY | 12/1438 | 49/23056 | 0.2448980 | 3.926542 | 5.289042 | 0.0000352 | 0.0003285 | 0.0002112 | ITGA10/ITGA6/ITGA4/PLD1/ITGA2/ADRB2/ITGA8/ITGA5/ITGA7/EDNRB/ITGA11/ITGA3 | 12 |
| GOBP_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 17/1438 | 90/23056 | 0.1888889 | 3.028527 | 4.972945 | 0.0000360 | 0.0003355 | 0.0002157 | ERRFI1/PTPRC/AGT/TGFA/EPHA4/ZFYVE28/DOK7/EPGN/EREG/BTC/EGF/HBEGF/CAV1/GPRC5A/CCL5/PRNP/PDGFB | 17 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_GROWTH | GOBP_NEGATIVE_REGULATION_OF_CELL_GROWTH | GOBP_NEGATIVE_REGULATION_OF_CELL_GROWTH | 27/1438 | 186/23056 | 0.1451613 | 2.327426 | 4.688004 | 0.0000362 | 0.0003366 | 0.0002164 | CDA/TGFB2/AGT/BMP10/SERPINE2/SEMA3B/WNT5A/BCL6/OSTN/SLIT2/SPP1/SEMA5A/DAB2/GJA1/INHBA/SEMA3C/SEMA3A/SEMA3D/NRP1/WT1/PTPRJ/CRYAB/BDKRB1/OSGIN1/SEMA6B/MAG/TGFB1 | 27 |
| HP_GASTROINTESTINAL_OBSTRUCTION | HP_GASTROINTESTINAL_OBSTRUCTION | HP_GASTROINTESTINAL_OBSTRUCTION | 15/1438 | 73/23056 | 0.2054795 | 3.294530 | 5.064144 | 0.0000368 | 0.0003419 | 0.0002198 | ECE1/PTPN22/FCGR2A/MITF/GDNF/TENT5A/IL6/SEMA3C/SEMA3D/EXT1/WT1/TNFRSF1A/EDNRB/CAVIN1/TGFB1 | 15 |
| HP_ABNORMALITY_OF_THE_PALM | HP_ABNORMALITY_OF_THE_PALM | HP_ABNORMALITY_OF_THE_PALM | 52/1438 | 467/23056 | 0.1113490 | 1.785301 | 4.421815 | 0.0000373 | 0.0003470 | 0.0002231 | TNFRSF1B/PTCH2/NEXN/KCNN3/LAMC2/LAMB3/DES/COL7A1/TNNC1/WNT5A/CD96/SLCO2A1/FGFRL1/FGFR3/DOK7/DSP/TFAP2A/CAP2/LAMA4/GJA1/PERP/SASH1/CSGALNACT1/TRPS1/EXT1/COL14A1/TPM2/MYPN/VCL/ANKRD1/BAG3/FGFR2/CRYAB/C1R/IGF1/BMP4/ACTC1/FBN1/TPM1/KRT17/JUP/DLX4/NOG/KCNJ2/ITGB4/RHBDF2/PIEZO2/DSG2/SERPINB7/RIN2/GPC4/BGN | 52 |
| HP_CONGENITAL_MALFORMATION_OF_THE_LEFT_HEART | HP_CONGENITAL_MALFORMATION_OF_THE_LEFT_HEART | HP_CONGENITAL_MALFORMATION_OF_THE_LEFT_HEART | 10/1438 | 35/23056 | 0.2857143 | 4.580966 | 5.467973 | 0.0000376 | 0.0003490 | 0.0002243 | KYNU/GJA1/PKD1L1/NOTCH1/WT1/MYRF/SMAD6/FOXF1/GATA6/GATA5 | 10 |
| XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | XU_HGF_SIGNALING_NOT_VIA_AKT1_48HR_UP | 10/1438 | 35/23056 | 0.2857143 | 4.580966 | 5.467973 | 0.0000376 | 0.0003490 | 0.0002243 | ECE1/CDCP1/ITPR3/STC1/PLAU/CD44/MMP1/PHLDA1/RIN2/HMOX1 | 10 |
| ALFANO_MYC_TARGETS | ALFANO_MYC_TARGETS | ALFANO_MYC_TARGETS | 32/1438 | 239/23056 | 0.1338912 | 2.146729 | 4.596048 | 0.0000376 | 0.0003490 | 0.0002243 | AGRN/RUNX3/CCN1/S100A10/TGFB2/LTBP1/ITGA6/ACKR3/MYLK/ITGB5/MGLL/MME/DAB2/SPARC/TRIP6/STC1/ANXA1/GSN/PLAU/VCL/TCF7L2/ADM/EMP1/ITGA7/PHLDA1/BMP4/SOX9/MAG/KCNN4/NPAS1/TGM2/SDC4 | 32 |
| DORN_ADENOVIRUS_INFECTION_24HR_DN | DORN_ADENOVIRUS_INFECTION_24HR_DN | DORN_ADENOVIRUS_INFECTION_24HR_DN | 11/1438 | 42/23056 | 0.2619048 | 4.199218 | 5.352131 | 0.0000379 | 0.0003511 | 0.0002257 | EPHA2/CCN1/COL7A1/PLK2/ELL2/IER3/IL6/NFKB2/NFKBIA/TNFRSF12A/KRT19 | 11 |
| GOBP_POSITIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | 11/1438 | 42/23056 | 0.2619048 | 4.199218 | 5.352131 | 0.0000379 | 0.0003511 | 0.0002257 | TNFRSF1B/SERPINE2/HES1/PTPRZ1/PTN/SHH/NOTCH1/MAG/TGFB1/BMP2/LIF | 11 |
| GOBP_EMBRYO_IMPLANTATION | GOBP_EMBRYO_IMPLANTATION | GOBP_EMBRYO_IMPLANTATION | 13/1438 | 57/23056 | 0.2280702 | 3.656736 | 5.179473 | 0.0000379 | 0.0003511 | 0.0002257 | PTGS2/IL1B/TGFBR2/SPP1/DDR1/GJA1/STC1/PCSK5/HMX3/ARHGDIB/MMP2/ITGB4/LIF | 13 |
| GOBP_SOMITOGENESIS | GOBP_SOMITOGENESIS | GOBP_SOMITOGENESIS | 14/1438 | 65/23056 | 0.2153846 | 3.453343 | 5.108464 | 0.0000382 | 0.0003533 | 0.0002271 | WNT5A/LEF1/FOXC1/TBX18/SEMA3C/DMRT2/CRB2/NOTCH1/DKK1/ALDH1A2/FOXB1/FOXF1/LHX1/MEOX1 | 14 |
| HP_HEMOPTYSIS | HP_HEMOPTYSIS | HP_HEMOPTYSIS | 14/1438 | 65/23056 | 0.2153846 | 3.453343 | 5.108464 | 0.0000382 | 0.0003533 | 0.0002271 | PTPN22/FCGR2A/TGFB2/COL3A1/COL5A2/IL17RC/TGFBR2/MYLK/SLC34A2/COL5A1/FAS/SCNN1A/FBN1/TGFB1 | 14 |
| GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | GOBP_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS | 33/1438 | 250/23056 | 0.1320000 | 2.116406 | 4.577432 | 0.0000383 | 0.0003536 | 0.0002273 | TNFRSF4/PTPN22/MR1/PTPRC/NLRP3/IL1R1/IL1B/WNT5A/SPON2/DDX60/F2RL1/MZB1/HLA-E/RAET1E/IL6/CD36/COLEC10/DDX58/ANXA1/MBL2/PTPRJ/KLRD1/KLRC4-KLRK1/STAT6/IL4R/FOXF1/DHX58/C3/IL12RB1/TGFB1/NECTIN2/HMOX1/RAC2 | 33 |
| HP_ABNORMALITY_OF_THE_NASAL_DORSUM | HP_ABNORMALITY_OF_THE_NASAL_DORSUM | HP_ABNORMALITY_OF_THE_NASAL_DORSUM | 30/1438 | 218/23056 | 0.1376147 | 2.206428 | 4.615885 | 0.0000387 | 0.0003571 | 0.0002296 | MMP23B/HSPG2/COL3A1/TWIST2/FGFRL1/FGFR3/FOXC1/RUNX2/TENT5A/FAM20C/BMPER/GLI3/SHH/FGF20/CSGALNACT1/ASPH/GAS1/ITGA8/FGFR2/ALX4/EFEMP2/GRIP1/IGF1/ZIC2/NFKBIA/FBN1/COL1A1/SOX9/MN1/ARSL | 30 |
| GOCC_FIBRILLAR_COLLAGEN_TRIMER | GOCC_FIBRILLAR_COLLAGEN_TRIMER | GOCC_FIBRILLAR_COLLAGEN_TRIMER | 6/1438 | 12/23056 | 0.5000000 | 8.016690 | 6.270443 | 0.0000388 | 0.0003577 | 0.0002300 | COL3A1/COL5A2/COL27A1/COL5A1/LUM/COL1A1 | 6 |
| HP_APLASIA_HYPOPLASIA_OF_THE_BLADDER | HP_APLASIA_HYPOPLASIA_OF_THE_BLADDER | HP_APLASIA_HYPOPLASIA_OF_THE_BLADDER | 6/1438 | 12/23056 | 0.5000000 | 8.016690 | 6.270443 | 0.0000388 | 0.0003577 | 0.0002300 | LAMC2/LAMB3/ITGA6/GRIP1/FREM2/ITGB4 | 6 |
| HP_ORAL_MUCOSAL_BLISTERS | HP_ORAL_MUCOSAL_BLISTERS | HP_ORAL_MUCOSAL_BLISTERS | 6/1438 | 12/23056 | 0.5000000 | 8.016690 | 6.270443 | 0.0000388 | 0.0003577 | 0.0002300 | LAMC2/LAMB3/ITGA6/COL7A1/MMP1/ITGB4 | 6 |
| HP_ABNORMALITY_OF_FACIAL_SOFT_TISSUE | HP_ABNORMALITY_OF_FACIAL_SOFT_TISSUE | HP_ABNORMALITY_OF_FACIAL_SOFT_TISSUE | 54/1438 | 492/23056 | 0.1097561 | 1.759761 | 4.393452 | 0.0000396 | 0.0003644 | 0.0002343 | AGRN/PTPN22/COL5A2/DES/COL6A3/PPARG/LAMB2/CD96/DOK7/ADAMTS3/ARHGAP24/SH3TC2/ADAMTS2/TFAP2A/PSMB8/PSMB9/COL12A1/GJA1/LAMA2/GLI3/TMEM270/EPHB4/FLNC/PODXL/ANGPT1/TPM2/GSN/CRB2/COL5A1/MYPN/COL13A1/MYOF/BAG3/WT1/CRYAB/TNFRSF1A/ITGA7/SIX1/MYO1E/PIEZO1/KRT17/COL1A1/ITGB4/CACNA1A/TGFB1/SIX5/RIN2/COL6A2/APOL1/PDGFB/FRMPD4/SRPX2/TBC1D8B/ARHGEF6 | 54 |
| GOBP_HEPATICOBILIARY_SYSTEM_DEVELOPMENT | GOBP_HEPATICOBILIARY_SYSTEM_DEVELOPMENT | GOBP_HEPATICOBILIARY_SYSTEM_DEVELOPMENT | 22/1438 | 137/23056 | 0.1605839 | 2.574703 | 4.767772 | 0.0000397 | 0.0003652 | 0.0002348 | TGFA/CPS1/CLDN1/HES1/ITGA2/TNFAIP3/CITED2/SOD2/IL6/GLI3/MET/PTN/ANXA1/PTPN3/NOTCH1/GLI1/SERPINA10/ALDH1A2/SOX9/GATA6/CEBPB/HMOX1 | 22 |
| WP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS | WP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS | WP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS | 20/1438 | 118/23056 | 0.1694915 | 2.717522 | 4.824139 | 0.0000399 | 0.0003669 | 0.0002359 | WNT5A/FGFR3/FGF5/EGF/FGF18/PDGFA/FZD1/FGF20/FZD6/FZD8/FGFR2/FZD4/WNT10B/BMP4/FOS/SMAD6/NOG/LIF/PDGFB/WNT7B | 20 |
| GOBP_VASOCONSTRICTION | GOBP_VASOCONSTRICTION | GOBP_VASOCONSTRICTION | 16/1438 | 82/23056 | 0.1951220 | 3.128464 | 4.979769 | 0.0000400 | 0.0003680 | 0.0002365 | ECE1/HTR1D/EDN2/PTGS2/AGT/HRH1/EDN1/CAV1/HTR7/ADM/ARHGAP42/KCNA5/EDNRB/MMP2/ADRA1D/CYSLTR1 | 16 |
| BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | BOYAULT_LIVER_CANCER_SUBCLASS_G56_DN | 7/1438 | 17/23056 | 0.4117647 | 6.601980 | 5.959207 | 0.0000404 | 0.0003693 | 0.0002374 | BHLHE40/PLD1/F2RL1/IER3/CCN2/THBS2/IL4R | 7 |
| GOBP_CHRONIC_INFLAMMATORY_RESPONSE | GOBP_CHRONIC_INFLAMMATORY_RESPONSE | GOBP_CHRONIC_INFLAMMATORY_RESPONSE | 7/1438 | 17/23056 | 0.4117647 | 6.601980 | 5.959207 | 0.0000404 | 0.0003693 | 0.0002374 | VCAM1/VNN1/TNFAIP3/IDO1/THBS1/CYP19A1/CCL5 | 7 |
| GOBP_COLLAGEN_ACTIVATED_SIGNALING_PATHWAY | GOBP_COLLAGEN_ACTIVATED_SIGNALING_PATHWAY | GOBP_COLLAGEN_ACTIVATED_SIGNALING_PATHWAY | 7/1438 | 17/23056 | 0.4117647 | 6.601980 | 5.959207 | 0.0000404 | 0.0003693 | 0.0002374 | ITGA2/DDR1/UBASH3B/ITGA11/COL1A1/COL4A6/COL4A5 | 7 |
| GOBP_GLOMERULAR_MESANGIUM_DEVELOPMENT | GOBP_GLOMERULAR_MESANGIUM_DEVELOPMENT | GOBP_GLOMERULAR_MESANGIUM_DEVELOPMENT | 7/1438 | 17/23056 | 0.4117647 | 6.601980 | 5.959207 | 0.0000404 | 0.0003693 | 0.0002374 | CD34/PDGFA/NOTCH1/WT1/BMP4/SERPINB7/PDGFB | 7 |
| HP_INCREASED_CIRCULATING_IGG_LEVEL | HP_INCREASED_CIRCULATING_IGG_LEVEL | HP_INCREASED_CIRCULATING_IGG_LEVEL | 7/1438 | 17/23056 | 0.4117647 | 6.601980 | 5.959207 | 0.0000404 | 0.0003693 | 0.0002374 | CASP10/IL7R/STING1/PSMB8/FAS/NCKAP1L/TGFB1 | 7 |
| HP_REDUCED_SYSTOLIC_FUNCTION | HP_REDUCED_SYSTOLIC_FUNCTION | HP_REDUCED_SYSTOLIC_FUNCTION | 7/1438 | 17/23056 | 0.4117647 | 6.601980 | 5.959207 | 0.0000404 | 0.0003693 | 0.0002374 | DES/DSP/TRDN/TPM2/MYPN/JUP/JPH2 | 7 |
| WP_PLATELETMEDIATED_INTERACTIONS_WITH_VASCULAR_AND_CIRCULATING_CELLS | WP_PLATELETMEDIATED_INTERACTIONS_WITH_VASCULAR_AND_CIRCULATING_CELLS | WP_PLATELETMEDIATED_INTERACTIONS_WITH_VASCULAR_AND_CIRCULATING_CELLS | 7/1438 | 17/23056 | 0.4117647 | 6.601980 | 5.959207 | 0.0000404 | 0.0003693 | 0.0002374 | VCAM1/TGFB2/IL1B/SELPLG/CCL5/ICAM1/TGFB1 | 7 |
| HP_ALOPECIA | HP_ALOPECIA | HP_ALOPECIA | 29/1438 | 208/23056 | 0.1394231 | 2.235423 | 4.616125 | 0.0000406 | 0.0003708 | 0.0002384 | TNFRSF1B/PADI3/PTPN22/ECM1/LAMC2/LAMB3/ITGB6/COL3A1/COL7A1/WNT5A/CLDN1/SPP1/IL7R/DSP/HFE/GJA1/PERP/SASH1/NOTCH1/NFKB2/HTRA1/ALX4/MMP1/KRT17/JUP/ITGB4/BMP2/RIN2/COL18A1 | 29 |
| KATSANOU_ELAVL1_TARGETS_DN | KATSANOU_ELAVL1_TARGETS_DN | KATSANOU_ELAVL1_TARGETS_DN | 23/1438 | 147/23056 | 0.1564626 | 2.508624 | 4.732503 | 0.0000408 | 0.0003730 | 0.0002398 | IFI16/PRG4/MGLL/SLCO2A1/IGSF10/CXCL6/NPNT/OSMR/FST/IQGAP2/EDIL3/TGFBI/LAMA2/FAM126A/ANXA8L1/CD44/FOSL1/LAYN/VWA5A/EPS8/SERPINB2/COL6A2/HAUS7 | 23 |
| HP_ABNORMAL_NUMBER_OF_TEETH | HP_ABNORMAL_NUMBER_OF_TEETH | HP_ABNORMAL_NUMBER_OF_TEETH | 41/1438 | 340/23056 | 0.1205882 | 1.933437 | 4.472113 | 0.0000410 | 0.0003740 | 0.0002404 | HSPG2/KCNN3/LAMC2/LAMB3/TGFA/CCDC141/WNT5A/CLDN1/FGFRL1/FGFR3/ADAMTS3/FAT4/ADAMTS2/FOXC1/DSP/TFAP2A/RUNX2/GJA1/PERP/TMEM270/SEMA3A/SHH/TRPS1/EXT1/GAS1/FGFR2/CREB3L1/C1S/C1R/WNT10B/GLI1/HMGA2/ZIC2/NFKBIA/BMP4/MAF/DLX4/DLX3/KCNJ2/ITGB4/CACNA1A | 41 |
| CUI_TCF21_TARGETS_2_UP | CUI_TCF21_TARGETS_2_UP | CUI_TCF21_TARGETS_2_UP | 49/1438 | 433/23056 | 0.1131640 | 1.814401 | 4.412263 | 0.0000410 | 0.0003743 | 0.0002406 | C1QTNF12/VCAM1/ECM1/CFH/LYPD6B/FAP/COL3A1/NRP2/FN1/EPHA4/GXYLT2/CCDC80/SLIT2/TGFBI/ADAMTS2/LAMA4/GJA1/LAMA2/PDGFA/BMPER/GLI3/SEMA3C/CADPS2/PTN/CLU/MATN2/CTHRC1/ZFPM2/CCN4/PAPSS2/PAMR1/KRT8/KRT18/HMGA2/GRIP1/LUM/IGF1/POSTN/NFATC4/BMP4/FBLN5/CLDN6/COL1A1/GATA6/PRNP/TGM2/COL6A2/LGALS1/CELSR1 | 49 |
| GOBP_DEVELOPMENT_OF_PRIMARY_FEMALE_SEXUAL_CHARACTERISTICS | GOBP_DEVELOPMENT_OF_PRIMARY_FEMALE_SEXUAL_CHARACTERISTICS | GOBP_DEVELOPMENT_OF_PRIMARY_FEMALE_SEXUAL_CHARACTERISTICS | 19/1438 | 109/23056 | 0.1743119 | 2.794809 | 4.844209 | 0.0000414 | 0.0003775 | 0.0002427 | FOXL2/SLIT2/KDR/EREG/FST/FOXC1/INHBA/ZFPM2/DMRTA1/WT1/FZD4/PGR/MMP14/CYP19A1/NUPR1/MMP2/CEBPB/COL9A3/DACH2 | 19 |
| GOBP_SMOOTH_MUSCLE_CELL_MIGRATION | GOBP_SMOOTH_MUSCLE_CELL_MIGRATION | GOBP_SMOOTH_MUSCLE_CELL_MIGRATION | 17/1438 | 91/23056 | 0.1868132 | 2.995247 | 4.918564 | 0.0000418 | 0.0003801 | 0.0002444 | S100A11/AGT/SLIT2/ITGA2/DDR1/PDGFA/SERPINE1/PLAT/HAS2/CCN4/NRP1/PLAU/IGF1/TPM1/MYOCD/CCL5/PDGFB | 17 |
| LU_IL4_SIGNALING | LU_IL4_SIGNALING | LU_IL4_SIGNALING | 17/1438 | 91/23056 | 0.1868132 | 2.995247 | 4.918564 | 0.0000418 | 0.0003801 | 0.0002444 | RASGRP3/BHLHE40/MGLL/BCL6/SEL1L3/VEGFC/TLR3/CCN2/TNFAIP3/IL6/NEK6/ALOX5/VCL/WT1/IL4R/CCL5/TNFRSF11A | 17 |
| RIZKI_TUMOR_INVASIVENESS_3D_DN | RIZKI_TUMOR_INVASIVENESS_3D_DN | RIZKI_TUMOR_INVASIVENESS_3D_DN | 34/1438 | 262/23056 | 0.1297710 | 2.080668 | 4.537188 | 0.0000418 | 0.0003804 | 0.0002446 | PTPRC/IKBKE/IL1R1/SP110/UBA7/TLR3/SOX30/FGF18/SEMA3C/PON3/SLC26A4/MEST/IDO1/CA1/CA3/TPM2/CEMIP2/WT1/SLCO2B1/CASP1/KRT7/POSTN/ESRRB/HCN4/IL32/ACSM3/RRAD/PECAM1/SLC16A3/CLUL1/SLC14A1/SCN1B/BMP2/MYH9 | 34 |
| GOBP_RESPONSE_TO_HYDROGEN_PEROXIDE | GOBP_RESPONSE_TO_HYDROGEN_PEROXIDE | GOBP_RESPONSE_TO_HYDROGEN_PEROXIDE | 21/1438 | 128/23056 | 0.1640625 | 2.630476 | 4.770794 | 0.0000426 | 0.0003875 | 0.0002491 | EDN1/TNFAIP3/SOD2/IL6/AQP1/MET/GPR37/ADAM9/TRPA1/ANXA1/FOSL1/CRYAB/KCNA5/STAT6/MMP2/NQO1/COL1A1/KLF2/AXL/SIRPA/HMOX1 | 21 |
| HP_ABNORMAL_LUNG_DEVELOPMENT | HP_ABNORMAL_LUNG_DEVELOPMENT | HP_ABNORMAL_LUNG_DEVELOPMENT | 31/1438 | 230/23056 | 0.1347826 | 2.161021 | 4.563975 | 0.0000435 | 0.0003945 | 0.0002536 | HSPG2/AGT/CFAP221/RARB/FGFR3/DOK7/DNAH5/MCIDAS/CCNO/RREB1/TENT5A/ADGRG6/FAM20C/BMPER/GLI3/SHH/FGF20/ZFPM2/RSPO2/ITGA8/WT1/MYRF/GLI1/GRIP1/FREM2/ZIC2/GLDN/FOXF1/PIEZO2/GATA6/GPC4 | 31 |
| GOBP_REGULATION_OF_HEART_GROWTH | GOBP_REGULATION_OF_HEART_GROWTH | GOBP_REGULATION_OF_HEART_GROWTH | 15/1438 | 74/23056 | 0.2027027 | 3.250009 | 4.999891 | 0.0000435 | 0.0003945 | 0.0002536 | BMP10/TGFBR2/EDN1/CITED2/FGF20/ZFPM2/NOTCH1/FGFR2/WT1/YAP1/GLI1/IGF1/NOG/GATA6/RUNX1 | 15 |
| LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | 15/1438 | 74/23056 | 0.2027027 | 3.250009 | 4.999891 | 0.0000435 | 0.0003945 | 0.0002536 | CCN1/COL7A1/ITGB5/DDR1/FZD1/MET/SH2D4A/TNFRSF1A/BMF/BCL2A1/HAPLN3/IL12RB1/COL6A2/LGALS1/COL4A6 | 15 |
| HP_PERIAURICULAR_SKIN_PITS | HP_PERIAURICULAR_SKIN_PITS | HP_PERIAURICULAR_SKIN_PITS | 12/1438 | 50/23056 | 0.2400000 | 3.848011 | 5.199486 | 0.0000438 | 0.0003963 | 0.0002548 | MITF/FGFRL1/TFAP2A/EDN1/CITED2/ZFPM2/SIX1/SALL1/KCNJ2/GATA6/GATA5/GPC4 | 12 |
| ZHAN_MULTIPLE_MYELOMA_MS_UP | ZHAN_MULTIPLE_MYELOMA_MS_UP | ZHAN_MULTIPLE_MYELOMA_MS_UP | 12/1438 | 50/23056 | 0.2400000 | 3.848011 | 5.199486 | 0.0000438 | 0.0003963 | 0.0002548 | SERPINE2/MITF/FGFR3/MYO10/PCSK5/FZD8/VWA5A/PPM1H/CDYL2/DSG2/CLIC6/BACE2 | 12 |
| GOBP_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | GOBP_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | GOBP_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | 27/1438 | 188/23056 | 0.1436170 | 2.302666 | 4.625431 | 0.0000438 | 0.0003963 | 0.0002548 | ERRFI1/ZC3H12A/PTPN22/PTPRC/CD34/IL1A/WNT5A/SPON2/TLR3/HLA-E/TNFAIP3/IL6/GPNMB/CD36/CLU/ANGPT1/CD274/DDX58/PTPRJ/IGF1/NFATC4/THBS1/IL27RA/ZFP36/AXL/BCL3/SIRPA | 27 |
| GOBP_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS | GOBP_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS | GOBP_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS | 9/1438 | 29/23056 | 0.3103448 | 4.975877 | 5.525447 | 0.0000446 | 0.0004023 | 0.0002586 | SHH/RSPO2/EXT1/FGFR2/YAP1/BMP4/FOXF1/SOX9/CELSR1 | 9 |
| GOBP_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | 9/1438 | 29/23056 | 0.3103448 | 4.975877 | 5.525447 | 0.0000446 | 0.0004023 | 0.0002586 | WNT9A/EFEMP1/RARB/NKX3-2/ADAMTS12/CCN4/BMP4/NOG/SOX9 | 9 |
| GOBP_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | 9/1438 | 29/23056 | 0.3103448 | 4.975877 | 5.525447 | 0.0000446 | 0.0004023 | 0.0002586 | PTGS2/IL1A/IL1B/IL6/SULF1/C3AR1/C3/TGFB1/C5AR1 | 9 |
| GOMF_INSULIN_LIKE_GROWTH_FACTOR_BINDING | GOMF_INSULIN_LIKE_GROWTH_FACTOR_BINDING | GOMF_INSULIN_LIKE_GROWTH_FACTOR_BINDING | 9/1438 | 29/23056 | 0.3103448 | 4.975877 | 5.525447 | 0.0000446 | 0.0004023 | 0.0002586 | CCN1/CRIM1/ITGA6/CCN2/HTRA4/CCN4/HTRA1/IGFBP6/ITGB4 | 9 |
| LU_TUMOR_VASCULATURE_UP | LU_TUMOR_VASCULATURE_UP | LU_TUMOR_VASCULATURE_UP | 9/1438 | 29/23056 | 0.3103448 | 4.975877 | 5.525447 | 0.0000446 | 0.0004023 | 0.0002586 | CMTM8/SPP1/TNFRSF21/SCIN/STC1/PAMR1/POSTN/ADAP2/MXRA5 | 9 |
| PID_INTEGRIN2_PATHWAY | PID_INTEGRIN2_PATHWAY | PID_INTEGRIN2_PATHWAY | 9/1438 | 29/23056 | 0.3103448 | 4.975877 | 5.525447 | 0.0000446 | 0.0004023 | 0.0002586 | CCN1/VCAM1/FCGR2A/SPON2/TGFBI/PLAT/PLAU/C3/ICAM1 | 9 |
| GOBP_RESPONSE_TO_XENOBIOTIC_STIMULUS | GOBP_RESPONSE_TO_XENOBIOTIC_STIMULUS | GOBP_RESPONSE_TO_XENOBIOTIC_STIMULUS | 47/1438 | 411/23056 | 0.1143552 | 1.833501 | 4.397391 | 0.0000451 | 0.0004063 | 0.0002612 | PTGS2/TGFB2/SRD5A2/TGFA/CYP26B1/NPAS2/SULT1C3/IL1B/AOX1/CPS1/TGFBR2/AADAC/VEGFC/TLR3/AHRR/ITGA2/CCNO/CRHBP/PCSK1/EDN1/SOD2/PDGFA/AHR/INHBA/SEMA3C/FZD1/PON3/TRPA1/TNFRSF11B/ANKRD1/CYP26A1/FOSL1/NNMT/NCKAP1L/FOS/CYP46A1/THBS1/MMP2/NQO1/GIP/ITGA3/COL1A1/GATA6/PRNP/NFATC2/HMOX1/APOBEC3A | 47 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | GOBP_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | GOBP_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING | 20/1438 | 119/23056 | 0.1680672 | 2.694686 | 4.780228 | 0.0000452 | 0.0004065 | 0.0002613 | C1QTNF12/EGF/SEMA5A/HBEGF/TPBG/PDGFA/MET/ANGPT1/TEK/AKR1C3/TCF7L2/PTPRJ/THBS1/TNFAIP8L3/CSF3/CCR7/C1QTNF1/GDF15/AXL/TGFB1 | 20 |
| HP_NAIL_DYSTROPHY | HP_NAIL_DYSTROPHY | HP_NAIL_DYSTROPHY | 20/1438 | 119/23056 | 0.1680672 | 2.694686 | 4.780228 | 0.0000452 | 0.0004065 | 0.0002613 | TNFRSF1B/LAMC2/LAMB3/ITGA6/COL7A1/STING1/DSP/RUNX2/PERP/SASH1/COL14A1/GSN/NOTCH1/NFKB2/MMP1/MAF/KRT17/JUP/ITGA3/ITGB4 | 20 |
| WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES | WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES | WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES | 20/1438 | 119/23056 | 0.1680672 | 2.694686 | 4.780228 | 0.0000452 | 0.0004065 | 0.0002613 | WNT9A/PPARG/WNT5A/FGFR3/FGF5/FGF18/RUNX2/GLI3/FZD1/FZD6/NOTCH1/FZD8/FGFR2/FZD4/WNT10B/PRKD1/BMP4/SOX9/BMP2/WNT7B | 20 |
| HP_BRUISING_SUSCEPTIBILITY | HP_BRUISING_SUSCEPTIBILITY | HP_BRUISING_SUSCEPTIBILITY | 23/1438 | 148/23056 | 0.1554054 | 2.491674 | 4.695322 | 0.0000455 | 0.0004095 | 0.0002632 | TGFB2/COL3A1/COL5A2/NABP1/CASP10/TGFBR2/MYLK/ADAMTS2/TENT5A/STX11/GSN/COL5A1/PLAU/FAS/VWF/TNFRSF1A/C1S/C1R/FBN1/COL1A1/RIN2/RUNX1/MYH9 | 23 |
| HP_SCARRING | HP_SCARRING | HP_SCARRING | 25/1438 | 168/23056 | 0.1488095 | 2.385920 | 4.649894 | 0.0000457 | 0.0004103 | 0.0002638 | RPE65/ECM1/LAMC2/LAMB3/ITGA6/COL3A1/COL5A2/COL6A3/TGFBR2/COL7A1/CLDN1/CFI/TGFBI/ADAMTS2/TFAP2A/COL12A1/AHR/TNFRSF11B/COL5A1/MMP1/C1S/C1R/COL1A1/ITGB4/COL6A2 | 25 |
| GOCC_CLUSTER_OF_ACTIN_BASED_CELL_PROJECTIONS | GOCC_CLUSTER_OF_ACTIN_BASED_CELL_PROJECTIONS | GOCC_CLUSTER_OF_ACTIN_BASED_CELL_PROJECTIONS | 24/1438 | 158/23056 | 0.1518987 | 2.435450 | 4.669519 | 0.0000459 | 0.0004119 | 0.0002648 | RHOC/CYBRD1/MME/SLC34A2/ABCG2/SLC7A11/ITPR3/CLIC5/SCIN/AQP1/CD36/SLC26A4/ATP6V0A4/IDO1/TRPA1/B4GALT1/TMC1/TRPM6/EPS8L2/EPS8/SOAT2/MYO1E/SLC28A1/MYH9 | 24 |
| HP_ABNORMAL_AORTIC_VALVE_PHYSIOLOGY | HP_ABNORMAL_AORTIC_VALVE_PHYSIOLOGY | HP_ABNORMAL_AORTIC_VALVE_PHYSIOLOGY | 24/1438 | 158/23056 | 0.1518987 | 2.435450 | 4.669519 | 0.0000459 | 0.0004119 | 0.0002648 | LDLRAP1/TGFB2/TGFBR2/MYLK/TENT5A/GJA1/TMEM270/DDX58/NOTCH1/FAS/WT1/EFEMP2/ROBO4/VWF/LTBP2/FBLN5/FBN1/SMAD6/HCN4/FOXF1/GATA6/SCN1B/CYP24A1/GATA5 | 24 |
| BLANCO_MELO_COVID19_BRONCHIAL_EPITHELIAL_CELLS_SARS_COV_2_INFECTION_DN | BLANCO_MELO_COVID19_BRONCHIAL_EPITHELIAL_CELLS_SARS_COV_2_INFECTION_DN | BLANCO_MELO_COVID19_BRONCHIAL_EPITHELIAL_CELLS_SARS_COV_2_INFECTION_DN | 13/1438 | 58/23056 | 0.2241379 | 3.593689 | 5.100832 | 0.0000461 | 0.0004127 | 0.0002653 | PADI3/NID1/EPHA4/MYLK/GPNMB/PDK4/PTPRZ1/BBOX1/MAF/KRT15/THBD/MN1/MXRA5 | 13 |
| GOBP_EMBRYONIC_DIGIT_MORPHOGENESIS | GOBP_EMBRYONIC_DIGIT_MORPHOGENESIS | GOBP_EMBRYONIC_DIGIT_MORPHOGENESIS | 13/1438 | 58/23056 | 0.2241379 | 3.593689 | 5.100832 | 0.0000461 | 0.0004127 | 0.0002653 | ECE1/OSR1/WNT5A/GJA1/GLI3/SHH/FZD6/NOTCH1/ALX4/FREM2/BMP4/SALL1/NOG | 13 |
| GOBP_RESPONSE_TO_AMYLOID_BETA | GOBP_RESPONSE_TO_AMYLOID_BETA | GOBP_RESPONSE_TO_AMYLOID_BETA | 13/1438 | 58/23056 | 0.2241379 | 3.593689 | 5.100832 | 0.0000461 | 0.0004127 | 0.0002653 | VCAM1/ITGA4/EPHA4/ADRB2/GJA1/CD36/MMP3/CASP4/IGF1/MMP2/ICAM1/CACNA1A/PRNP | 13 |
| HP_VENTRICULAR_TACHYCARDIA | HP_VENTRICULAR_TACHYCARDIA | HP_VENTRICULAR_TACHYCARDIA | 13/1438 | 58/23056 | 0.2241379 | 3.593689 | 5.100832 | 0.0000461 | 0.0004127 | 0.0002653 | TECRL/MYOZ2/DSP/TRDN/SEMA3A/SCNN1A/TPM1/HCN4/JUP/KCNJ2/DSG2/SCN1B/JPH2 | 13 |
| MEBARKI_HCC_PROGENITOR_FZD8CRD_DN | MEBARKI_HCC_PROGENITOR_FZD8CRD_DN | MEBARKI_HCC_PROGENITOR_FZD8CRD_DN | 51/1438 | 459/23056 | 0.1111111 | 1.781487 | 4.361710 | 0.0000467 | 0.0004176 | 0.0002685 | SPSB1/DHRS3/CYP4X1/ITGA10/C1orf54/AGT/SULT1C2/DPP4/COL3A1/NABP1/SP100/TGFBR2/COL7A1/ALDH1L1/MME/VEPH1/CLDN16/CXCL1/SPP1/CFI/TDO2/SMLR1/WIPF3/TCIM/ST3GAL1/TPM2/COL27A1/APBB1IP/FZD8/PPP1R3C/HHEX/SLC22A18AS/SLC22A18/EHF/EFEMP2/FZD4/SLC2A14/SPX/SERPINA1/SLC28A1/HAPLN3/ACSM3/LDHD/ACSF2/ATP8B3/CREB3L3/APOE/C5AR1/SLC6A16/PNPLA3/ARSL | 51 |
| GOBP_RESPONSE_TO_VITAMIN | GOBP_RESPONSE_TO_VITAMIN | GOBP_RESPONSE_TO_VITAMIN | 16/1438 | 83/23056 | 0.1927711 | 3.090772 | 4.921428 | 0.0000468 | 0.0004180 | 0.0002687 | PTGS2/CYP26B1/IL1A/KYNU/SPP1/IL15/ITGA2/SOD2/STC1/AQP3/CYP26A1/POSTN/ALDH1A2/COL1A1/CYP24A1/MN1 | 16 |
| HP_NEOPLASM_BY_HISTOLOGY | HP_NEOPLASM_BY_HISTOLOGY | HP_NEOPLASM_BY_HISTOLOGY | 41/1438 | 342/23056 | 0.1198830 | 1.922130 | 4.431113 | 0.0000469 | 0.0004186 | 0.0002691 | MMP23B/HSPG2/PTCH2/KCNN3/CASP10/TGFBR2/COL7A1/MITF/FGFR3/ADAMTS3/FAT4/VEGFC/GDNF/TFAP2A/TBX18/PERP/FAM20C/BMPER/GLI3/PDGFRL/ZFPM2/EXT1/COL14A1/FAS/SLC22A18/WT1/ALX4/PTPRJ/MMP1/FOXO1/KRT17/COL1A1/SOX9/RUNX1/COL18A1/PDGFB/SSX1/SSX2/COL4A6/COL4A5/GPC4 | 41 |
| LU_EZH2_TARGETS_DN | LU_EZH2_TARGETS_DN | LU_EZH2_TARGETS_DN | 46/1438 | 400/23056 | 0.1150000 | 1.843839 | 4.390885 | 0.0000471 | 0.0004201 | 0.0002701 | TRIM63/RNASEL/LAMC2/ATP2B4/RASSF5/NLRP3/COL3A1/NABP1/TGFBR2/FSTL1/MYLK/HEG1/PLSCR4/P3H2/CLDN1/ELL2/GRAMD2B/HBEGF/BMP6/CCN2/TNFAIP3/ADGRG6/SEMA3C/FZD1/PLAT/ASPH/MYBL1/LRATD2/TNFSF15/DKK1/PLAU/VCL/PAPSS2/PTPRE/ADM/SERPINH1/MMP3/SLC7A7/THBS1/DSG2/ALPK2/AXL/CYP24A1/BACE2/TBC1D8B/GPC4 | 46 |
| GOCC_ACTIN_FILAMENT | GOCC_ACTIN_FILAMENT | GOCC_ACTIN_FILAMENT | 19/1438 | 110/23056 | 0.1727273 | 2.769402 | 4.797595 | 0.0000472 | 0.0004201 | 0.0002701 | LMOD1/ACKR2/ACTBL2/WIPF3/LMOD2/PDLIM2/TEK/TPM2/ANXA1/AIF1L/MICAL2/EHBP1L1/LCP1/ACTC1/TPM1/COTL1/GAS2L1/RAC2/PLS3 | 19 |
| GROSS_HYPOXIA_VIA_HIF1A_DN | GROSS_HYPOXIA_VIA_HIF1A_DN | GROSS_HYPOXIA_VIA_HIF1A_DN | 19/1438 | 110/23056 | 0.1727273 | 2.769402 | 4.797595 | 0.0000472 | 0.0004201 | 0.0002701 | ERRFI1/CCN1/S100A13/BHLHE40/FST/HBEGF/EDN1/CCN2/CAV1/TCIM/KLF4/ANKRD1/ADM/MMP3/NFKBIA/FOS/GPRC5C/ZFP36/MYH9 | 19 |
| GENTILE_UV_HIGH_DOSE_UP | GENTILE_UV_HIGH_DOSE_UP | GENTILE_UV_HIGH_DOSE_UP | 8/1438 | 23/23056 | 0.3478261 | 5.576828 | 5.663794 | 0.0000473 | 0.0004201 | 0.0002701 | HBEGF/COL13A1/MMP3/NUPR1/RRAD/FSTL3/IL11/SAT1 | 8 |
| GOBP_CHONDROCYTE_PROLIFERATION | GOBP_CHONDROCYTE_PROLIFERATION | GOBP_CHONDROCYTE_PROLIFERATION | 8/1438 | 23/23056 | 0.3478261 | 5.576828 | 5.663794 | 0.0000473 | 0.0004201 | 0.0002701 | FGFR3/LEF1/CCN2/STC1/EXT1/HMGA2/MMP14/SOX9 | 8 |
| HP_ASCENDING_AORTIC_DISSECTION | HP_ASCENDING_AORTIC_DISSECTION | HP_ASCENDING_AORTIC_DISSECTION | 8/1438 | 23/23056 | 0.3478261 | 5.576828 | 5.663794 | 0.0000473 | 0.0004201 | 0.0002701 | TGFB2/COL3A1/TGFBR2/MYLK/NOTCH1/FBN1/SMAD6/GATA5 | 8 |
| HP_JOINT_SUBLUXATION | HP_JOINT_SUBLUXATION | HP_JOINT_SUBLUXATION | 8/1438 | 23/23056 | 0.3478261 | 5.576828 | 5.663794 | 0.0000473 | 0.0004201 | 0.0002701 | ADAMTS2/GLI3/COL5A1/EFEMP2/FBLN5/MMP2/COL1A1/ARSL | 8 |
| WP_GDNFRET_SIGNALING_AXIS | WP_GDNFRET_SIGNALING_AXIS | WP_GDNFRET_SIGNALING_AXIS | 8/1438 | 23/23056 | 0.3478261 | 5.576828 | 5.663794 | 0.0000473 | 0.0004201 | 0.0002701 | SLIT2/FAT4/GDNF/FOXC1/GLI3/BMP4/SALL1/LHX1 | 8 |
| GOBP_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | 11/1438 | 43/23056 | 0.2558140 | 4.101562 | 5.250279 | 0.0000481 | 0.0004267 | 0.0002743 | EREG/PRDM6/SOD2/SHH/FGFR2/EFEMP2/BMP4/RBPMS2/MYOCD/NFATC2/PDGFB | 11 |
| MUELLER_METHYLATED_IN_GLIOBLASTOMA | MUELLER_METHYLATED_IN_GLIOBLASTOMA | MUELLER_METHYLATED_IN_GLIOBLASTOMA | 11/1438 | 43/23056 | 0.2558140 | 4.101562 | 5.250279 | 0.0000481 | 0.0004267 | 0.0002743 | CDA/RUNX3/CXCL2/IER3/KRT4/KRT19/KRT17/SSX1/SSX2/SPANXB1/SPANXA1 | 11 |
| GOBP_FOREBRAIN_DEVELOPMENT | GOBP_FOREBRAIN_DEVELOPMENT | GOBP_FOREBRAIN_DEVELOPMENT | 44/1438 | 377/23056 | 0.1167109 | 1.871270 | 4.399118 | 0.0000481 | 0.0004267 | 0.0002743 | ATP2B4/SRD5A2/DLX1/DLX2/CCDC141/COL3A1/NRP2/RARB/WNT5A/HES1/SLIT2/ANXA3/LEF1/FAT4/SLC7A11/SEMA5A/DNAH5/PCSK1/ID4/MDGA1/AQP1/INHBA/GLI3/SEMA3A/FOXP2/SHH/EXT1/NOTCH1/NRP1/DKK1/FGFR2/GLI1/BMP4/ALDH1A2/FOXB1/ALDH1A3/SALL1/LHX1/HAP1/NOG/SEMA6B/AXL/BMP2/WNT7B | 44 |
| GOBP_REGULATION_OF_ORGAN_GROWTH | GOBP_REGULATION_OF_ORGAN_GROWTH | GOBP_REGULATION_OF_ORGAN_GROWTH | 18/1438 | 101/23056 | 0.1782178 | 2.857434 | 4.824915 | 0.0000483 | 0.0004278 | 0.0002750 | BMP10/TGFBR2/FOXC1/EDN1/CITED2/FGF20/ZFPM2/NOTCH1/FGFR2/WT1/YAP1/YBX3/GLI1/IGF1/LATS2/NOG/GATA6/RUNX1 | 18 |
| HP_ABNORMAL_VAGINA_MORPHOLOGY | HP_ABNORMAL_VAGINA_MORPHOLOGY | HP_ABNORMAL_VAGINA_MORPHOLOGY | 18/1438 | 101/23056 | 0.1782178 | 2.857434 | 4.824915 | 0.0000483 | 0.0004278 | 0.0002750 | SRD5A2/COL3A1/IL17RC/COL7A1/GLI3/ZFPM2/RSPO2/ITGA8/FGFR2/WT1/STAT6/GRIP1/FREM2/DACT1/SALL1/SOX9/COL4A6/COL4A5 | 18 |
| GOBP_RESPONSE_TO_OXIDATIVE_STRESS | GOBP_RESPONSE_TO_OXIDATIVE_STRESS | GOBP_RESPONSE_TO_OXIDATIVE_STRESS | 49/1438 | 436/23056 | 0.1123853 | 1.801916 | 4.359938 | 0.0000489 | 0.0004330 | 0.0002784 | ZC3H12A/PTGS2/IL1A/SOD3/SLC7A11/EDN1/MICB/PTPRK/VNN1/TNFAIP3/SOD2/IL6/AQP1/CD36/FZD1/MET/GPR37/RBPMS/ADAM9/TRPA1/CA3/ANXA1/PTGS1/AKR1C3/ALOX5/MBL2/AIFM2/FOSL1/ALDH3B1/MMP3/CRYAB/KCNA5/STAT6/MSRB3/FOXO1/MMP14/PRKD1/FOS/FBLN5/TPM1/MMP2/NQO1/COL1A1/KLF2/AXL/APOE/SIRPA/PRNP/HMOX1 | 49 |
| GOBP_LUNG_EPITHELIUM_DEVELOPMENT | GOBP_LUNG_EPITHELIUM_DEVELOPMENT | GOBP_LUNG_EPITHELIUM_DEVELOPMENT | 10/1438 | 36/23056 | 0.2777778 | 4.453717 | 5.348593 | 0.0000492 | 0.0004346 | 0.0002794 | ERRFI1/THRB/SHH/FGFR2/YAP1/BMP4/SOX9/GATA6/KLF2/WNT7B | 10 |
| HP_SOFT_SKIN | HP_SOFT_SKIN | HP_SOFT_SKIN | 10/1438 | 36/23056 | 0.2777778 | 4.453717 | 5.348593 | 0.0000492 | 0.0004346 | 0.0002794 | KCNN3/COL5A2/TGFBR2/SPARC/ADAMTS2/COL12A1/COL5A1/EFEMP2/C1R/COL1A1 | 10 |
| GOBP_RESPONSE_TO_TEMPERATURE_STIMULUS | GOBP_RESPONSE_TO_TEMPERATURE_STIMULUS | GOBP_RESPONSE_TO_TEMPERATURE_STIMULUS | 26/1438 | 179/23056 | 0.1452514 | 2.328871 | 4.603244 | 0.0000495 | 0.0004372 | 0.0002811 | CASQ1/PTGS2/CD34/IL1A/CASP8/TRPM8/PLAC8/ADRB2/GMPR/MICA/MICB/SLC25A27/SOD2/TCIM/TRPA1/BAG3/ADM/IGF1/FOXO1/NFKBIA/FOS/DIO2/THBS1/TRPV2/METRNL/HMOX1 | 26 |
| GOBP_RHO_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_RHO_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 22/1438 | 139/23056 | 0.1582734 | 2.537657 | 4.689670 | 0.0000498 | 0.0004395 | 0.0002825 | COL3A1/HEG1/BCL6/F2RL1/MET/GPR20/NRP1/SYNPO2L/EPS8L2/ARHGAP42/APOC3/APOA1/ARHGDIB/EPS8/CDH13/ITGA3/APOE/CDC42EP5/CDC42EP1/CELSR1/STARD8/LPAR4 | 22 |
| GOBP_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | GOBP_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | GOBP_REGULATION_OF_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY | 46/1438 | 401/23056 | 0.1147132 | 1.839241 | 4.372511 | 0.0000501 | 0.0004420 | 0.0002841 | FBLIM1/TRABD2B/GBP5/RHOC/LMOD1/IKBKE/TRABD2A/CAPG/HES1/SLIT2/CSF2/ARHGAP18/SCIN/CCL26/CD36/MET/LMOD2/ARHGEF5/CLU/GSN/DKK1/MMP1/MMP3/CRYAB/EPS8/WNT10B/NCKAP1L/NAV3/DNAJC15/LCP1/AJUBA/DACT1/BMF/SMAD6/COTL1/PIEZO1/CSF3/CCR7/SOX9/TMC8/TGFB1/APOE/CDC42EP5/CDC42EP1/MSN/TENM1 | 46 |
| HP_RENAL_INSUFFICIENCY | HP_RENAL_INSUFFICIENCY | HP_RENAL_INSUFFICIENCY | 44/1438 | 378/23056 | 0.1164021 | 1.866319 | 4.380017 | 0.0000512 | 0.0004515 | 0.0002903 | PTPN22/CFH/NLRP3/KYNU/CASP10/FN1/COL7A1/LAMB2/MME/CLDN16/ARHGAP24/SPP1/CFI/TBX18/CCN2/TMEM270/CAV1/GSN/CRB2/FAS/SAA1/WT1/PYGM/MMP1/SCNN1A/FLT1/SLC7A7/DACT1/SIX1/MYO1E/SALL1/MYOCD/LHX1/ITGA3/MOCOS/C3/APOE/SIX5/THBD/APOL1/MYH9/TBC1D8B/COL4A6/COL4A5 | 44 |
| SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3 | 15/1438 | 75/23056 | 0.2000000 | 3.206676 | 4.936725 | 0.0000512 | 0.0004515 | 0.0002903 | RHOC/NID1/ITGA6/TGFBR2/SPARC/DDR1/SERPINE1/FABP4/TMEM71/PLEK2/EHD4/TPM1/TNFRSF12A/NUPR1/COL1A1 | 15 |
| GOBP_ACTIN_FILAMENT_ORGANIZATION | GOBP_ACTIN_FILAMENT_ORGANIZATION | GOBP_ACTIN_FILAMENT_ORGANIZATION | 50/1438 | 449/23056 | 0.1113586 | 1.785454 | 4.334878 | 0.0000521 | 0.0004590 | 0.0002951 | S1PR1/RHOC/S100A10/HMCN1/LMOD1/CAPG/XIRP2/CATIP/XIRP1/PHLDB2/ITGB5/SLIT2/SEMA5A/IQGAP2/F2RL1/ARHGAP18/CCN2/MICALL2/SCIN/CCL26/MET/LMOD2/ZYX/ARHGEF5/TPM2/GSN/AIF1L/NRP1/SYNPO2L/MICAL2/APOA1/EPS8/RND1/NCKAP1L/LCP1/ACTC1/CGNL1/MYO1E/TPM1/COTL1/CSF3/CCR7/GMFG/CDC42EP5/SDC4/GAS2L1/RAC2/CDC42EP1/PLS3/TENM1 | 50 |
| HP_PROPTOSIS | HP_PROPTOSIS | HP_PROPTOSIS | 32/1438 | 243/23056 | 0.1316872 | 2.111392 | 4.491933 | 0.0000522 | 0.0004592 | 0.0002952 | HSPG2/PTPN22/NLRP3/COL3A1/FN1/THRB/TGFBR2/WNT5A/MITF/FGFRL1/FGFR3/FOXC1/PSMB8/CITED2/FAM20C/SHH/ZFPM2/FGFR2/EFEMP2/SERPINH1/FBN1/MMP2/MAF/COL1A1/SOX9/GATA6/TNFRSF11A/TGFB1/RRAS/GATA5/PDGFB/BGN | 32 |
| FOSTER_KDM1A_TARGETS_UP | FOSTER_KDM1A_TARGETS_UP | FOSTER_KDM1A_TARGETS_UP | 34/1438 | 265/23056 | 0.1283019 | 2.057113 | 4.463925 | 0.0000527 | 0.0004638 | 0.0002982 | CDA/PTPN22/SRD5A2/RASGRP3/TMEM40/RBM47/PLAC8/SH3RF2/GMPR/TPBG/CRYBG1/SASH1/SLC26A4/MDFIC/MBL2/SFTPD/CCDC172/VWA5A/SLC6A13/NCKAP1L/SELPLG/LRCOL1/ALOX5AP/MMP2/TRPV2/MYL4/COPZ2/HOXB7/EBI3/FXYD5/CDC42EP5/CLIC6/MX1/MAGEA10 | 34 |
| GOBP_CELLULAR_KETONE_METABOLIC_PROCESS | GOBP_CELLULAR_KETONE_METABOLIC_PROCESS | GOBP_CELLULAR_KETONE_METABOLIC_PROCESS | 29/1438 | 211/23056 | 0.1374408 | 2.203640 | 4.529982 | 0.0000529 | 0.0004648 | 0.0002988 | PTGS2/ATP2B4/SRD5A2/IL1B/KYNU/PPARG/SLC7A11/TDO2/DAB2/BMP6/PDK4/CAV1/AKR1B10/IDO1/ANXA1/AKR1C3/AIFM2/ADM/APOC3/APOA1/EDNRB/SLC7A7/CYP46A1/CYP19A1/CES1/GIP/SOX9/CYP4F11/BMP2 | 29 |
| TAVOR_CEBPA_TARGETS_UP | TAVOR_CEBPA_TARGETS_UP | TAVOR_CEBPA_TARGETS_UP | 12/1438 | 51/23056 | 0.2352941 | 3.772560 | 5.112216 | 0.0000540 | 0.0004740 | 0.0003047 | GBP1/PTPRC/SOD2/ARHGEF5/ANXA1/PTPN3/VCL/C3AR1/GLIPR1/BCL2A1/HMOX1/MLC1 | 12 |
| VILIMAS_NOTCH1_TARGETS_UP | VILIMAS_NOTCH1_TARGETS_UP | VILIMAS_NOTCH1_TARGETS_UP | 12/1438 | 51/23056 | 0.2352941 | 3.772560 | 5.112216 | 0.0000540 | 0.0004740 | 0.0003047 | TNFRSF18/DDR1/TRAF1/NFKB2/BIRC3/NFKBIA/BCL2A1/LAT/CCL5/CCR7/ICAM1/RELB | 12 |
| LEE_AGING_CEREBELLUM_UP | LEE_AGING_CEREBELLUM_UP | LEE_AGING_CEREBELLUM_UP | 16/1438 | 84/23056 | 0.1904762 | 3.053977 | 4.863961 | 0.0000545 | 0.0004778 | 0.0003071 | GBP4/CTSS/AGT/ITGB5/SPP1/THBS2/NOTCH1/TRIM5/SELPLG/FOS/BCL2A1/CD68/MYH8/AXL/APOE/HMOX1 | 16 |
| HP_FEVER | HP_FEVER | HP_FEVER | 42/1438 | 356/23056 | 0.1179775 | 1.891579 | 4.372461 | 0.0000553 | 0.0004843 | 0.0003114 | GFI1/PTPN22/LAMC2/CFH/LAMB3/NLRP3/GYPC/NABP1/BCL6/SLC34A2/ARHGAP24/SPP1/TLR3/IL7R/STING1/PSMB8/PSMB9/TNFAIP3/STX11/IL6/PTPN3/CRB2/FAS/WT1/BIRC3/TNFRSF1A/SCNN1A/KRT8/KRT18/STAT6/EPB42/MYO1E/PSMB10/COL1A1/ELANE/CD70/CACNA1A/PRNP/RUNX1/APOL1/IL2RB/TBC1D8B | 42 |
| GOCC_BRUSH_BORDER | GOCC_BRUSH_BORDER | GOCC_BRUSH_BORDER | 18/1438 | 102/23056 | 0.1764706 | 2.829420 | 4.775717 | 0.0000553 | 0.0004843 | 0.0003114 | CYBRD1/MME/SLC34A2/ABCG2/SLC7A11/ITPR3/SCIN/AQP1/CD36/SLC26A4/ATP6V0A4/B4GALT1/TRPM6/EPS8/SOAT2/MYO1E/SLC28A1/MYH9 | 18 |
| HP_CIRRHOSIS | HP_CIRRHOSIS | HP_CIRRHOSIS | 22/1438 | 140/23056 | 0.1571429 | 2.519531 | 4.651130 | 0.0000556 | 0.0004871 | 0.0003132 | HJV/FCGR2A/CASP8/PPARG/HFE/CAV1/MET/PDGFRL/TNFSF15/NOTCH1/KRT8/KRT18/SLC7A7/PYGL/FOS/SERPINA1/IL21R/CAVIN1/IL12RB1/TGFB1/APOE/BMP2 | 22 |
| HP_HIP_DISLOCATION | HP_HIP_DISLOCATION | HP_HIP_DISLOCATION | 31/1438 | 233/23056 | 0.1330472 | 2.133196 | 4.483850 | 0.0000558 | 0.0004874 | 0.0003133 | AGRN/HSPG2/TBX15/COL3A1/COL5A2/COL6A3/WNT5A/CD96/FGFRL1/ADAMTS2/COL12A1/GJA1/GLI3/SHH/COLEC10/TPM2/GAS1/COL5A1/COL13A1/EFEMP2/ITGA7/ZIC2/SIX1/FBLN5/SMAD6/MYH8/COL1A1/SOX9/PIEZO2/COL6A2/GPC4 | 31 |
| BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 13/1438 | 59/23056 | 0.2203390 | 3.532779 | 5.023910 | 0.0000558 | 0.0004874 | 0.0003133 | LTBP1/EPHA4/PLSCR4/SLIT2/ID4/TPBG/NT5E/PERP/STX11/SEMA3C/MDFIC/TPK1/ADAMTS5 | 13 |
| CORRE_MULTIPLE_MYELOMA_DN | CORRE_MULTIPLE_MYELOMA_DN | CORRE_MULTIPLE_MYELOMA_DN | 13/1438 | 59/23056 | 0.2203390 | 3.532779 | 5.023910 | 0.0000558 | 0.0004874 | 0.0003133 | OLFML3/MME/NPR3/LAMA2/FZD1/CADPS2/CCN4/GAS1/IGF1/TNFRSF19/FOS/MAF/COLEC12 | 13 |
| SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | 13/1438 | 59/23056 | 0.2203390 | 3.532779 | 5.023910 | 0.0000558 | 0.0004874 | 0.0003133 | S100A2/IFI16/FN1/PLAC8/SPP1/CFI/INHBA/AKR1C3/SRGN/CD44/THBS1/ITM2A/IL13RA1 | 13 |
| HP_ABNORMAL_CRANIAL_NERVE_PHYSIOLOGY | HP_ABNORMAL_CRANIAL_NERVE_PHYSIOLOGY | HP_ABNORMAL_CRANIAL_NERVE_PHYSIOLOGY | 38/1438 | 311/23056 | 0.1221865 | 1.959062 | 4.391758 | 0.0000581 | 0.0005068 | 0.0003258 | AGRN/MMP23B/HSPG2/PTPN22/NLRP3/COL3A1/DES/COL6A3/LAMB2/DOK7/SH3TC2/TFAP2A/COL12A1/TENT5A/GJA1/LAMA2/TPM2/GSN/DKK1/MYPN/COL13A1/FAS/BAG3/CRYAB/TNFRSF1A/DACT1/SIX1/SALL1/ITGB4/TNFRSF11A/TGFB1/SIX5/PRNP/COL6A2/PDGFB/FRMPD4/SRPX2/ARHGEF6 | 38 |
| GOBP_MOTOR_NEURON_AXON_GUIDANCE | GOBP_MOTOR_NEURON_AXON_GUIDANCE | GOBP_MOTOR_NEURON_AXON_GUIDANCE | 9/1438 | 30/23056 | 0.3000000 | 4.810014 | 5.385576 | 0.0000602 | 0.0005225 | 0.0003359 | LAMC2/EPHA4/SLIT2/HOXA2/SEMA3A/NRP1/LHX1/NOG/RAC2 | 9 |
| GOBP_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | 9/1438 | 30/23056 | 0.3000000 | 4.810014 | 5.385576 | 0.0000602 | 0.0005225 | 0.0003359 | ERRFI1/TGFA/ZFYVE28/EPGN/EREG/BTC/EGF/HBEGF/GPRC5A | 9 |
| GOBP_RESPONSE_TO_GONADOTROPIN | GOBP_RESPONSE_TO_GONADOTROPIN | GOBP_RESPONSE_TO_GONADOTROPIN | 9/1438 | 30/23056 | 0.3000000 | 4.810014 | 5.385576 | 0.0000602 | 0.0005225 | 0.0003359 | SRD5A2/EDN1/INHBA/PLAT/PAPPA/NOTCH1/WT1/ITGA3/GATA6 | 9 |
| KEGG_O_GLYCAN_BIOSYNTHESIS | KEGG_O_GLYCAN_BIOSYNTHESIS | KEGG_O_GLYCAN_BIOSYNTHESIS | 9/1438 | 30/23056 | 0.3000000 | 4.810014 | 5.385576 | 0.0000602 | 0.0005225 | 0.0003359 | GALNT5/GALNT3/GALNT15/GALNTL6/GALNT10/GALNT17/ST3GAL1/GALNT18/GALNT9 | 9 |
| KIM_LRRC3B_TARGETS | KIM_LRRC3B_TARGETS | KIM_LRRC3B_TARGETS | 9/1438 | 30/23056 | 0.3000000 | 4.810014 | 5.385576 | 0.0000602 | 0.0005225 | 0.0003359 | IFI16/CXCL1/C9/HLA-E/HLA-C/TAPBP/IFITM2/SERPINA1/CCL5 | 9 |
| TING_SILENCED_BY_DICER | TING_SILENCED_BY_DICER | TING_SILENCED_BY_DICER | 9/1438 | 30/23056 | 0.3000000 | 4.810014 | 5.385576 | 0.0000602 | 0.0005225 | 0.0003359 | CCN1/GBP3/TM4SF1/SLC4A4/SPARC/SERPINA1/HOXB2/LIPG/APOBEC3G | 9 |
| BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_RUXOLITINIB_DN | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_RUXOLITINIB_DN | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_RUXOLITINIB_DN | 15/1438 | 76/23056 | 0.1973684 | 3.164483 | 4.874613 | 0.0000602 | 0.0005225 | 0.0003359 | GBP1/OLFML3/SPP1/CFI/SCIN/AKR1B10/PDGFRL/ANGPT1/IFITM2/SERPINH1/CRYAB/KRT4/CES1/PSMB10/CYP4F11 | 15 |
| GOBP_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | 15/1438 | 76/23056 | 0.1973684 | 3.164483 | 4.874613 | 0.0000602 | 0.0005225 | 0.0003359 | PTGS2/KDR/VEGFC/PLK2/FGF18/ANGPT1/ANXA1/JCAD/NRP1/PRKD1/THBS1/TGFB1/HMOX1/PDGFB/SRPX2 | 15 |
| YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | 15/1438 | 76/23056 | 0.1973684 | 3.164483 | 4.874613 | 0.0000602 | 0.0005225 | 0.0003359 | CAPG/TEC/DSP/CCN2/PERP/CA3/PRSS23/KRT18/HMGA2/TNFRSF19/NUPR1/ITGB4/C3/PRNP/SDC4 | 15 |
| GOBP_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 43/1438 | 369/23056 | 0.1165312 | 1.868388 | 4.337035 | 0.0000605 | 0.0005243 | 0.0003371 | ECM1/IFI16/PTGS2/TGFB2/AGT/CRIM1/TFPI/SERPINE2/COL6A3/COL7A1/ITIH3/SERPINB1/CD109/AQP1/SERPINE1/ANXA1/KLF4/CRB2/ANXA8L1/ANXA8/CD44/SERPINH1/BIRC3/CARD16/CRYAB/APOC3/APOA1/KLRC4-KLRK1/NCKAP1L/SERPINE3/SERPINA10/SERPINA6/SERPINA1/THBS1/ANXA2/SERPINB7/SERPINB2/SERPINB8/TNFSF14/C3/PRNP/WFDC10B/BIRC7 | 43 |
| HP_PROLONGED_BLEEDING_TIME | HP_PROLONGED_BLEEDING_TIME | HP_PROLONGED_BLEEDING_TIME | 11/1438 | 44/23056 | 0.2500000 | 4.008345 | 5.151468 | 0.0000606 | 0.0005245 | 0.0003372 | COL5A2/ADAMTS2/CD36/TEK/COL5A1/VWF/COL1A1/ITGB4/RIN2/RUNX1/MYH9 | 11 |
| STREICHER_LSM1_TARGETS_UP | STREICHER_LSM1_TARGETS_UP | STREICHER_LSM1_TARGETS_UP | 11/1438 | 44/23056 | 0.2500000 | 4.008345 | 5.151468 | 0.0000606 | 0.0005245 | 0.0003372 | ELF3/ITPKB/MYLK/BCL6/INPP4B/CITED2/IL6/IL15RA/FGFR2/PDGFB/IL13RA1 | 11 |
| SHEPARD_BMYB_MORPHOLINO_DN | SHEPARD_BMYB_MORPHOLINO_DN | SHEPARD_BMYB_MORPHOLINO_DN | 28/1438 | 202/23056 | 0.1386139 | 2.222449 | 4.500694 | 0.0000607 | 0.0005250 | 0.0003375 | S1PR1/PTPN22/S100A10/DLX1/DLX2/CLDN1/PPP1R3G/SCIN/AQP1/CEBPD/SULF1/CA1/AQP3/SLC6A13/PYGL/MT2A/COTL1/MYH8/LHX1/KRT17/COL1A1/ACSF2/ITGB4/LIPG/C3/BLVRB/APOE/COL4A5 | 28 |
| HP_SPARSE_HAIR | HP_SPARSE_HAIR | HP_SPARSE_HAIR | 39/1438 | 323/23056 | 0.1207430 | 1.935919 | 4.368832 | 0.0000607 | 0.0005250 | 0.0003375 | PTPN22/LAMC2/LAMB3/ITGB6/CCDC141/TWIST2/FOXL2/CLDN1/ADAMTS3/FAT4/STING1/DSP/TFAP2A/PSMB8/GJA1/PERP/ZFPM2/TRPS1/EXT1/GSN/NOTCH1/FAS/WT1/ALX4/WNT10B/HPD/SLC7A7/PRKD1/NFKBIA/BNC1/MAF/KRT17/JUP/DLX4/ITGA3/SOX9/ITGB4/AXL/RIN2 | 39 |
| GOBP_SMOOTH_MUSCLE_CONTRACTION | GOBP_SMOOTH_MUSCLE_CONTRACTION | GOBP_SMOOTH_MUSCLE_CONTRACTION | 19/1438 | 112/23056 | 0.1696429 | 2.719948 | 4.705915 | 0.0000609 | 0.0005259 | 0.0003381 | HTR1D/EDN2/PTGS2/ATP2B4/AGT/MYLK/NPNT/GDNF/ITGA2/ADRB2/EDN1/CAV1/SULF1/HTR7/ARHGAP42/SPX/EDNRB/MYOCD/CNN1 | 19 |
| GOBP_T_CELL_MEDIATED_IMMUNITY | GOBP_T_CELL_MEDIATED_IMMUNITY | GOBP_T_CELL_MEDIATED_IMMUNITY | 19/1438 | 112/23056 | 0.1696429 | 2.719948 | 4.705915 | 0.0000609 | 0.0005259 | 0.0003381 | TNFRSF1B/MR1/PTPRC/NLRP3/IL1R1/IL1B/IL7R/HFE/HLA-E/MICA/AHR/IL6/KLRD1/NCKAP1L/CD70/ICAM1/IL12RB1/NECTIN2/IL4I1 | 19 |
| MILI_PSEUDOPODIA_CHEMOTAXIS_DN | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | 48/1438 | 428/23056 | 0.1121495 | 1.798136 | 4.298629 | 0.0000613 | 0.0005289 | 0.0003400 | ECM1/ADAMTSL4/NRP2/FN1/ACKR3/LAMB2/SEMA3B/SLCO2A1/SOD3/ADRB2/HLA-E/DDR1/TAPBP/PLA2G7/CD109/TPBG/AQP1/EPHB4/SERPINE1/AKR1B10/PLAT/MATN2/TRPS1/PTGS1/COL5A1/NRP1/VCL/ITPRIP/GALNT18/C1S/C1R/SLC38A4/ITGA5/MMP14/FOS/THBS1/CSPG4/MSLN/ITGA3/SOCS3/TNFSF9/ZFP36/AXL/KCNN4/PRNP/ADAMTS5/COL4A6/COL4A5 | 48 |
| HP_SOMATIC_MUTATION | HP_SOMATIC_MUTATION | HP_SOMATIC_MUTATION | 25/1438 | 171/23056 | 0.1461988 | 2.344061 | 4.549838 | 0.0000615 | 0.0005304 | 0.0003410 | PTCH2/CASP10/CASP8/TGFBR2/LPP/FGFR3/IL6/MET/MSR1/PDGFRL/PLAG1/CTHRC1/EXT1/MAP3K8/FGFR2/SLC22A18/WT1/PTPRJ/OPCML/FLT3/FOXO1/RUNX1/SSX1/SSX2/GPC4 | 25 |
| HP_HEADACHE | HP_HEADACHE | HP_HEADACHE | 38/1438 | 312/23056 | 0.1217949 | 1.952783 | 4.370109 | 0.0000622 | 0.0005367 | 0.0003450 | PTPN22/CFH/NLRP3/KYNU/COL3A1/COL5A2/CASP10/TGFBR2/FGFR3/ARHGAP24/SPP1/CFI/EGF/TLR3/TENT5A/EPHB4/TPM2/CRB2/COL5A1/DKK1/FAS/FGFR2/HTRA1/WT1/ALX4/TNFRSF1A/ITGA7/FLT1/MYO1E/COL1A1/ELANE/CACNA1A/TGFB1/APOL1/PDGFB/NDP/SRPX2/TBC1D8B | 38 |
| GOBP_POSITIVE_REGULATION_OF_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_POSITIVE_REGULATION_OF_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_POSITIVE_REGULATION_OF_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | 7/1438 | 18/23056 | 0.3888889 | 6.235203 | 5.730621 | 0.0000625 | 0.0005374 | 0.0003455 | PPARG/DAB2/BMP6/RBPMS/BMP4/TGFB1/BMP2 | 7 |
| HP_ABNORMALITY_OF_THE_TEMPOROMANDIBULAR_JOINT | HP_ABNORMALITY_OF_THE_TEMPOROMANDIBULAR_JOINT | HP_ABNORMALITY_OF_THE_TEMPOROMANDIBULAR_JOINT | 7/1438 | 18/23056 | 0.3888889 | 6.235203 | 5.730621 | 0.0000625 | 0.0005374 | 0.0003455 | PTPN22/COL5A2/EDN1/LAMA2/COL5A1/COL1A1/IL2RB | 7 |
| HP_OPPORTUNISTIC_INFECTION | HP_OPPORTUNISTIC_INFECTION | HP_OPPORTUNISTIC_INFECTION | 7/1438 | 18/23056 | 0.3888889 | 6.235203 | 5.730621 | 0.0000625 | 0.0005374 | 0.0003455 | PTPRC/IL7R/MBL2/IL21R/ELANE/IL12RB1/TGFB1 | 7 |
| KIM_PTEN_TARGETS_UP | KIM_PTEN_TARGETS_UP | KIM_PTEN_TARGETS_UP | 7/1438 | 18/23056 | 0.3888889 | 6.235203 | 5.730621 | 0.0000625 | 0.0005374 | 0.0003455 | PLD1/SLC7A11/GALNT10/SKAP2/CPA4/PLAU/GDF15 | 7 |
| REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS | REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS | REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS | 7/1438 | 18/23056 | 0.3888889 | 6.235203 | 5.730621 | 0.0000625 | 0.0005374 | 0.0003455 | LOXL2/TLL2/LOXL4/LOXL1/COL1A1/COL4A6/COL4A5 | 7 |
| HP_APLASIA_HYPOPLASIA_OF_THE_LUNGS | HP_APLASIA_HYPOPLASIA_OF_THE_LUNGS | HP_APLASIA_HYPOPLASIA_OF_THE_LUNGS | 23/1438 | 151/23056 | 0.1523179 | 2.442170 | 4.585579 | 0.0000627 | 0.0005388 | 0.0003464 | HSPG2/AGT/RARB/FGFR3/DOK7/TENT5A/ADGRG6/FAM20C/BMPER/SHH/FGF20/ZFPM2/RSPO2/ITGA8/WT1/MYRF/GLI1/GRIP1/FREM2/ZIC2/GLDN/PIEZO2/GATA6 | 23 |
| GOBP_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 16/1438 | 85/23056 | 0.1882353 | 3.018048 | 4.807345 | 0.0000633 | 0.0005428 | 0.0003489 | GALNT3/WNT5A/FGFRL1/FGFR3/FGF5/FGF18/RUNX2/CCN2/FAM20C/FGF20/SULF1/EXT1/FGFR2/CREB3L1/THBS1/NOG | 16 |
| HP_PULMONARY_FIBROSIS | HP_PULMONARY_FIBROSIS | HP_PULMONARY_FIBROSIS | 16/1438 | 85/23056 | 0.1882353 | 3.018048 | 4.807345 | 0.0000633 | 0.0005428 | 0.0003489 | PTPN22/CASP10/SP110/SLC34A2/STING1/DSP/HFE/CCN2/CAV1/FAS/SERPINA1/BNC1/TGFB1/KCNN4/HMOX1/RAC2 | 16 |
| GOMF_ENDOPEPTIDASE_REGULATOR_ACTIVITY | GOMF_ENDOPEPTIDASE_REGULATOR_ACTIVITY | GOMF_ENDOPEPTIDASE_REGULATOR_ACTIVITY | 27/1438 | 192/23056 | 0.1406250 | 2.254694 | 4.502633 | 0.0000634 | 0.0005435 | 0.0003494 | AGT/CRIM1/TFPI/SERPINE2/COL6A3/COL7A1/ITIH3/SERPINB1/CD109/SERPINE1/CRB2/SERPINH1/BIRC3/CARD16/SERPINE3/SERPINA10/SERPINA6/SERPINA1/ANXA2/SERPINB7/SERPINB2/SERPINB8/TNFSF14/C3/PRNP/WFDC10B/BIRC7 | 27 |
| GOBP_NEGATIVE_REGULATION_OF_MUSCLE_HYPERTROPHY | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_HYPERTROPHY | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_HYPERTROPHY | 10/1438 | 37/23056 | 0.2702703 | 4.333346 | 5.233500 | 0.0000636 | 0.0005435 | 0.0003494 | ERRFI1/TNFRSF1B/TRIM63/ATP2B4/BMP10/PPARG/NOTCH1/TNFRSF1A/FOXO1/GATA5 | 10 |
| GOBP_NEURON_PROJECTION_EXTENSION_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE | GOBP_NEURON_PROJECTION_EXTENSION_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE | GOBP_NEURON_PROJECTION_EXTENSION_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE | 10/1438 | 37/23056 | 0.2702703 | 4.333346 | 5.233500 | 0.0000636 | 0.0005435 | 0.0003494 | NRP2/SEMA3B/WNT5A/SLIT2/SEMA5A/SEMA3C/SEMA3A/SEMA3D/NRP1/SEMA6B | 10 |
| GOBP_SPECIFICATION_OF_ANIMAL_ORGAN_IDENTITY | GOBP_SPECIFICATION_OF_ANIMAL_ORGAN_IDENTITY | GOBP_SPECIFICATION_OF_ANIMAL_ORGAN_IDENTITY | 10/1438 | 37/23056 | 0.2702703 | 4.333346 | 5.233500 | 0.0000636 | 0.0005435 | 0.0003494 | WNT5A/GDNF/GLI3/EXT1/DKK1/FGFR2/BMP4/SIX1/BMP2/GATA5 | 10 |
| GOBP_TYPE_2_IMMUNE_RESPONSE | GOBP_TYPE_2_IMMUNE_RESPONSE | GOBP_TYPE_2_IMMUNE_RESPONSE | 10/1438 | 37/23056 | 0.2702703 | 4.333346 | 5.233500 | 0.0000636 | 0.0005435 | 0.0003494 | ECM1/NLRP3/BCL6/IL6/IDO1/ANXA1/STAT6/IL4R/IL27RA/BCL3 | 10 |
| HP_HYPOPLASTIC_HEART | HP_HYPOPLASTIC_HEART | HP_HYPOPLASTIC_HEART | 10/1438 | 37/23056 | 0.2702703 | 4.333346 | 5.233500 | 0.0000636 | 0.0005435 | 0.0003494 | KYNU/GJA1/PKD1L1/NOTCH1/WT1/MYRF/SMAD6/FOXF1/GATA6/GATA5 | 10 |
| HP_MIXED_HEARING_IMPAIRMENT | HP_MIXED_HEARING_IMPAIRMENT | HP_MIXED_HEARING_IMPAIRMENT | 10/1438 | 37/23056 | 0.2702703 | 4.333346 | 5.233500 | 0.0000636 | 0.0005435 | 0.0003494 | FGFR3/SGMS2/TENT5A/GJA1/FAM20C/HOXA2/GDF6/FGFR2/SIX1/ARSL | 10 |
| GOBP_OLIGODENDROCYTE_DIFFERENTIATION | GOBP_OLIGODENDROCYTE_DIFFERENTIATION | GOBP_OLIGODENDROCYTE_DIFFERENTIATION | 17/1438 | 94/23056 | 0.1808511 | 2.899654 | 4.759790 | 0.0000641 | 0.0005471 | 0.0003517 | TNFRSF1B/DLX1/DLX2/HES1/ID4/TNFRSF21/GLI3/PTPRZ1/PTN/SHH/CLU/NOTCH1/MYRF/TRPC4/SOX8/SOX9/MAG | 17 |
| ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP | ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP | ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP | 36/1438 | 290/23056 | 0.1241379 | 1.990351 | 4.377225 | 0.0000647 | 0.0005524 | 0.0003551 | CCDC141/COL3A1/OSBPL10/PLSCR2/CXCL1/BTC/TMEM144/OSMR/C9/HSPB3/SMIM3/GMPR/ADGRF5/ADGRF4/RHAG/COL19A1/SCIN/IL6/SEMA3C/FZD1/RBPMS/SULF1/TMEM71/FZD8/HTR7/CCDC172/ELMOD1/YBX3/ARHGDIB/MSRB3/NAV3/PRKD1/COLEC12/SERPINB2/PRNP/MAGEA9 | 36 |
| GOBP_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT | GOBP_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT | GOBP_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT | 14/1438 | 68/23056 | 0.2058824 | 3.300990 | 4.900866 | 0.0000648 | 0.0005524 | 0.0003551 | EPHA2/CSF1/LBH/WNT5A/RREB1/DDR1/ZNF703/FGFR2/PGR/STAT6/FOXB1/FOXF1/CEBPB/WNT7B | 14 |
| GOBP_CAMERA_TYPE_EYE_MORPHOGENESIS | GOBP_CAMERA_TYPE_EYE_MORPHOGENESIS | GOBP_CAMERA_TYPE_EYE_MORPHOGENESIS | 20/1438 | 122/23056 | 0.1639344 | 2.628423 | 4.651162 | 0.0000650 | 0.0005539 | 0.0003561 | EPHA2/RPE65/IGFN1/WNT9A/THRB/WNT5A/COL8A1/KDR/TFAP2A/CITED2/GLI3/TSPAN12/CRB2/PITX3/CABP4/BMP4/ALDH1A3/SOX8/LHX1/SOX9 | 20 |
| GOMF_PEPTIDE_HORMONE_BINDING | GOMF_PEPTIDE_HORMONE_BINDING | GOMF_PEPTIDE_HORMONE_BINDING | 12/1438 | 52/23056 | 0.2307692 | 3.700011 | 5.027126 | 0.0000663 | 0.0005633 | 0.0003622 | ECE1/SCTR/VIPR1/NPR3/CRHBP/HCRTR2/INHBA/NPY4R2/CCKBR/EDNRB/GLP2R/EBI3 | 12 |
| HP_ABNORMAL_ANTERIOR_CHAMBER_MORPHOLOGY | HP_ABNORMAL_ANTERIOR_CHAMBER_MORPHOLOGY | HP_ABNORMAL_ANTERIOR_CHAMBER_MORPHOLOGY | 12/1438 | 52/23056 | 0.2307692 | 3.700011 | 5.027126 | 0.0000663 | 0.0005633 | 0.0003622 | RPE65/PTPN22/MITF/FOXC1/TSPAN12/COLEC10/LTBP2/FBN1/LOXL1/COL18A1/IL2RB/NDP | 12 |
| PRAMOONJAGO_SOX4_TARGETS_UP | PRAMOONJAGO_SOX4_TARGETS_UP | PRAMOONJAGO_SOX4_TARGETS_UP | 12/1438 | 52/23056 | 0.2307692 | 3.700011 | 5.027126 | 0.0000663 | 0.0005633 | 0.0003622 | IL1B/BHLHE40/IER3/TPBG/TNFAIP3/SOD2/SERPINE1/STC1/ADM/GPRC5A/ZFP36L1/GDF15 | 12 |
| GOBP_CALCIUM_MEDIATED_SIGNALING | GOBP_CALCIUM_MEDIATED_SIGNALING | GOBP_CALCIUM_MEDIATED_SIGNALING | 28/1438 | 203/23056 | 0.1379310 | 2.211501 | 4.471511 | 0.0000663 | 0.0005633 | 0.0003622 | EDN2/GBP1/VCAM1/CASQ1/PTPRC/NR5A2/ATP2B4/TRPM8/ACKR3/ACKR2/CCR3/KDR/CXCL8/MYOZ2/EDN1/RCAN2/MYOZ1/PTPRJ/IGF1/EDNRB/NFATC4/SLC24A4/LAT/CDH13/CCR7/CD22/PRNP/NFATC2 | 28 |
| GOBP_POSITIVE_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | GOBP_POSITIVE_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | GOBP_POSITIVE_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | 8/1438 | 24/23056 | 0.3333333 | 5.344460 | 5.491991 | 0.0000671 | 0.0005682 | 0.0003653 | CD53/GCM1/ADAM9/IL4R/TNFSF14/GDF15/EHD2/NFATC2 | 8 |
| GOBP_SUBPALLIUM_DEVELOPMENT | GOBP_SUBPALLIUM_DEVELOPMENT | GOBP_SUBPALLIUM_DEVELOPMENT | 8/1438 | 24/23056 | 0.3333333 | 5.344460 | 5.491991 | 0.0000671 | 0.0005682 | 0.0003653 | DLX1/DLX2/RARB/SLC7A11/INHBA/GLI3/FOXP2/ALDH1A3 | 8 |
| MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_DN | 8/1438 | 24/23056 | 0.3333333 | 5.344460 | 5.491991 | 0.0000671 | 0.0005682 | 0.0003653 | MET/RARRES2/C1S/KRT7/KRT8/KRT18/KRT19/JUP | 8 |
| MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | 8/1438 | 24/23056 | 0.3333333 | 5.344460 | 5.491991 | 0.0000671 | 0.0005682 | 0.0003653 | TMEM156/PDGFA/CTHRC1/PLAU/FOS/CA12/KRT17/COL6A2 | 8 |
| ZHANG_INTERFERON_RESPONSE | ZHANG_INTERFERON_RESPONSE | ZHANG_INTERFERON_RESPONSE | 8/1438 | 24/23056 | 0.3333333 | 5.344460 | 5.491991 | 0.0000671 | 0.0005682 | 0.0003653 | IFI16/SP110/RTP4/IFITM3/OASL/IRF9/MX2/MX1 | 8 |
| CHANG_IMMORTALIZED_BY_HPV31_DN | CHANG_IMMORTALIZED_BY_HPV31_DN | CHANG_IMMORTALIZED_BY_HPV31_DN | 13/1438 | 60/23056 | 0.2166667 | 3.473899 | 4.948638 | 0.0000672 | 0.0005692 | 0.0003659 | GBP1/GPA33/PTGS2/THRB/DSP/SAMD9/TAGLN/FOS/IFI35/SERPINB2/KLK6/MX2/MX1 | 13 |
| HP_NEPHROTIC_SYNDROME | HP_NEPHROTIC_SYNDROME | HP_NEPHROTIC_SYNDROME | 21/1438 | 132/23056 | 0.1590909 | 2.550765 | 4.608313 | 0.0000677 | 0.0005734 | 0.0003686 | NLRP3/CASP10/FN1/LAMB2/MME/SPP1/IL7R/TBX18/ZFPM2/GSN/CRB2/SAA1/WT1/APOA1/SERPINA1/MYO1E/ITGA3/SOX9/C3/TBC1D8B/COL4A5 | 21 |
| GOBP_POSITIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_ASTROCYTE_DIFFERENTIATION | 6/1438 | 13/23056 | 0.4615385 | 7.400021 | 5.953027 | 0.0000683 | 0.0005769 | 0.0003709 | SERPINE2/HES1/NOTCH1/MAG/BMP2/LIF | 6 |
| GOBP_POSITIVE_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY | 6/1438 | 13/23056 | 0.4615385 | 7.400021 | 5.953027 | 0.0000683 | 0.0005769 | 0.0003709 | TGFA/EPGN/EREG/BTC/EGF/HBEGF | 6 |
| ONGUSAHA_BRCA1_TARGETS_UP | ONGUSAHA_BRCA1_TARGETS_UP | ONGUSAHA_BRCA1_TARGETS_UP | 6/1438 | 13/23056 | 0.4615385 | 7.400021 | 5.953027 | 0.0000683 | 0.0005769 | 0.0003709 | ECM1/TGFBI/KRT13/APOE/COL18A1/HMOX1 | 6 |
| GOBP_KERATINOCYTE_DIFFERENTIATION | GOBP_KERATINOCYTE_DIFFERENTIATION | GOBP_KERATINOCYTE_DIFFERENTIATION | 22/1438 | 142/23056 | 0.1549296 | 2.484045 | 4.575041 | 0.0000692 | 0.0005845 | 0.0003758 | ERRFI1/EPHA2/TCHH/SPRR2F/CYP26B1/IL1A/WNT5A/EREG/FOXC1/DSP/CD109/HOXA7/ADAM9/AQP3/ANXA1/NOTCH1/AKR1C3/PLAAT4/YAP1/ZFP36L1/KRT17/ZFP36 | 22 |
| GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 36/1438 | 291/23056 | 0.1237113 | 1.983511 | 4.354578 | 0.0000695 | 0.0005868 | 0.0003772 | ZC3H12A/S100A13/TNFSF18/PTPRC/NLRP3/NMI/SUCNR1/BCL6/ANXA3/LEF1/F2RL1/DOCK2/IL6/TCIM/ST3GAL1/IFNE/ANXA1/APBB1IP/NCKAP1L/STAT6/LCP1/IL4R/LAT/FOXF1/IFI35/MILR1/ICAM1/IL27RA/IL12RB1/TGFB1/BCL3/RELB/HMOX1/RAC2/LGALS1/ITM2A | 36 |
| KUMAR_TARGETS_OF_MLL_AF9_FUSION | KUMAR_TARGETS_OF_MLL_AF9_FUSION | KUMAR_TARGETS_OF_MLL_AF9_FUSION | 46/1438 | 407/23056 | 0.1130221 | 1.812126 | 4.263346 | 0.0000718 | 0.0006052 | 0.0003891 | RNF220/MCOLN2/VCAM1/IFI16/MR1/PLA2G4A/LCT/GALNT3/NABP1/CLDN1/SPP1/LEF1/IL7R/ELL2/PPIC/DSP/DDR1/PLA2G7/COL19A1/PERP/CITED2/HOXA7/INHBA/RBPMS/ANGPT1/ANXA1/HMX3/TRIM5/MS4A4A/C1R/KLRD1/IGF1/TNFRSF19/POSTN/IRF9/CCL5/MYL4/MOCOS/SEMA6B/MAG/REM1/SDC4/USP18/ITM2A/PLS3/GPC4 | 46 |
| GOBP_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 18/1438 | 104/23056 | 0.1730769 | 2.775008 | 4.679085 | 0.0000720 | 0.0006065 | 0.0003899 | AGRN/EPHA2/S100A10/AGT/CLDN1/IL1RAP/KDR/GRID2/TPBG/THBS2/CAV1/TEK/NRP1/PTPRJ/AMIGO2/SDC4/SRPX2/SLITRK4 | 18 |
| HP_LIMB_JOINT_CONTRACTURE | HP_LIMB_JOINT_CONTRACTURE | HP_LIMB_JOINT_CONTRACTURE | 43/1438 | 372/23056 | 0.1155914 | 1.853321 | 4.279354 | 0.0000729 | 0.0006141 | 0.0003948 | MMP23B/ECE1/HSPG2/TBX15/LAMC2/PRG4/LAMB3/NLRP3/ACTG2/COL6A3/TWIST2/TGFBR2/WNT5A/FGFR3/DOK7/ADAMTS3/FAT4/SH3TC2/DSP/TFAP2A/PSMB8/COL12A1/GJA1/LAMA2/CCN2/GLI3/CAV1/SHH/TRPS1/TPM2/BAG3/FGFR2/ITGA7/BMP4/FBN1/MMP2/JUP/SGCA/NOG/ITGB4/PIEZO2/COL6A2/GPC4 | 43 |
| GOBP_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | GOBP_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | GOBP_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION | 20/1438 | 123/23056 | 0.1626016 | 2.607054 | 4.609000 | 0.0000731 | 0.0006157 | 0.0003958 | PTPRC/HES1/RBM47/KDR/FST/FOXC1/CITED2/INHBA/PTPRZ1/SHH/CEBPD/EXT1/NOTCH1/FLT3/FLT1/BMP4/MEOX1/HOXB3/FSTL3/TGFB1 | 20 |
| GOBP_LIPID_STORAGE | GOBP_LIPID_STORAGE | GOBP_LIPID_STORAGE | 16/1438 | 86/23056 | 0.1860465 | 2.982954 | 4.751554 | 0.0000733 | 0.0006164 | 0.0003962 | ZC3H12A/IKBKE/IL1B/PPARG/CDS1/IL6/CD36/CAV1/MEST/MSR1/APOA1/NFKBIA/CES1/C3/APOE/PLA2G4C | 16 |
| HP_ABNORMALITY_OF_PERIAURICULAR_REGION | HP_ABNORMALITY_OF_PERIAURICULAR_REGION | HP_ABNORMALITY_OF_PERIAURICULAR_REGION | 17/1438 | 95/23056 | 0.1789474 | 2.869131 | 4.708260 | 0.0000736 | 0.0006185 | 0.0003976 | FN1/MITF/FGFRL1/SEMA5A/TFAP2A/EDN1/CITED2/ZFPM2/FGFR2/DACT1/SIX1/SALL1/KCNJ2/GATA6/SIX5/GATA5/GPC4 | 17 |
| HP_ABNORMAL_ADIPOSE_TISSUE_MORPHOLOGY | HP_ABNORMAL_ADIPOSE_TISSUE_MORPHOLOGY | HP_ABNORMAL_ADIPOSE_TISSUE_MORPHOLOGY | 29/1438 | 215/23056 | 0.1348837 | 2.162642 | 4.417351 | 0.0000745 | 0.0006262 | 0.0004026 | FUCA1/NEXN/COL3A1/CASP10/DES/PPARG/TNNC1/PCSK1/ADAMTS2/DSP/CAP2/PSMB8/PSMB9/LAMA4/CAV1/MYPN/VCL/FAS/ANKRD1/BAG3/CRYAB/FOS/ACTC1/FBN1/TPM1/CAVIN1/COL1A1/DSG2/TGFB1 | 29 |
| HOLLERN_SQUAMOUS_BREAST_TUMOR | HOLLERN_SQUAMOUS_BREAST_TUMOR | HOLLERN_SQUAMOUS_BREAST_TUMOR | 25/1438 | 173/23056 | 0.1445087 | 2.316962 | 4.484295 | 0.0000746 | 0.0006262 | 0.0004026 | PADI1/PADI3/PTCH2/TCHH/IRX4/SNCAIP/ADTRP/GJA1/AHR/ZNF703/AQP3/KLF4/KRT80/KRT79/TNFRSF19/BMP4/MT1X/KRT15/KRT17/DLX3/GATA6/SERPINB2/SERPINB8/KLK6/BMP2 | 25 |
| ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN | 11/1438 | 45/23056 | 0.2444444 | 3.919271 | 5.055535 | 0.0000757 | 0.0006349 | 0.0004081 | TNFRSF9/AADAC/IL15/VEGFC/PLK2/ITPR3/AHR/SERPINE1/CAV2/PPP1R3C/AXL | 11 |
| HP_ABNORMAL_UTERUS_MORPHOLOGY | HP_ABNORMAL_UTERUS_MORPHOLOGY | HP_ABNORMAL_UTERUS_MORPHOLOGY | 21/1438 | 133/23056 | 0.1578947 | 2.531586 | 4.568628 | 0.0000758 | 0.0006357 | 0.0004086 | COL3A1/COL5A2/RARB/TGFBR2/FGFR3/PDGFRL/COL5A1/ITGA8/FGFR2/WT1/PTPRJ/STAT6/GRIP1/FREM2/DACT1/SALL1/FOXF1/COL1A1/NDP/COL4A6/COL4A5 | 21 |
| GOCC_ENDOCYTIC_VESICLE_MEMBRANE | GOCC_ENDOCYTIC_VESICLE_MEMBRANE | GOCC_ENDOCYTIC_VESICLE_MEMBRANE | 27/1438 | 194/23056 | 0.1391753 | 2.231450 | 4.442370 | 0.0000760 | 0.0006366 | 0.0004092 | LDLRAP1/RAB7B/TGFA/STAB1/WNT5A/EPGN/EREG/BTC/ANXA3/EGF/IL7R/HBEGF/ADRB2/HLA-E/HLA-C/TAPBP/CD36/CAV1/ATP6V0A4/MSR1/FZD4/RAB38/RAB20/COLEC12/APOE/RAC2/WNT7B | 27 |
| CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | 46/1438 | 408/23056 | 0.1127451 | 1.807685 | 4.245330 | 0.0000761 | 0.0006375 | 0.0004099 | ARHGEF16/TINAGL1/ELF3/DPP4/GALNT3/AOX1/IQCA1/HRH1/OSBPL10/WNT5A/MITF/SEL1L3/RBM47/CDS1/SEMA5A/EDIL3/FOXC1/ID4/TRIM38/PTPRK/AHR/MACC1/ITGB8/FZD1/FOXP2/MET/TPK1/SHH/TNFRSF10C/KLF4/PAPPA/AIF1L/PGGHG/PLAAT3/SYTL2/VWA5A/SCNN1A/KRT7/FREM2/EDNRB/MSLN/CLDN7/MYH8/GPRC5C/DSG2/CLIC6 | 46 |
| HP_CLEFT_UPPER_LIP | HP_CLEFT_UPPER_LIP | HP_CLEFT_UPPER_LIP | 24/1438 | 163/23056 | 0.1472393 | 2.360743 | 4.496481 | 0.0000763 | 0.0006385 | 0.0004105 | PTCH2/NUAK2/IL1B/WNT5A/FGFRL1/TFAP2A/GJA1/FAM20C/GLI3/SHH/FGF20/RSPO2/COLEC10/GAS1/ITGA8/YAP1/GRIP1/FREM2/ZIC2/JUP/MEOX1/DLX4/MID1/GPC4 | 24 |
| HP_ABNORMAL_PERICARDIUM_MORPHOLOGY | HP_ABNORMAL_PERICARDIUM_MORPHOLOGY | HP_ABNORMAL_PERICARDIUM_MORPHOLOGY | 14/1438 | 69/23056 | 0.2028986 | 3.253150 | 4.834234 | 0.0000767 | 0.0006409 | 0.0004120 | PTPN22/FCGR2A/PRG4/PTPN14/ADAMTS3/SPP1/FAT4/IL6/EPHB4/FAS/TNFRSF1A/MAF/GATA6/PLVAP | 14 |
| HP_LYMPHEDEMA | HP_LYMPHEDEMA | HP_LYMPHEDEMA | 14/1438 | 69/23056 | 0.2028986 | 3.253150 | 4.834234 | 0.0000767 | 0.0006409 | 0.0004120 | TIE1/PTPN14/NLRP3/BCL6/ADAMTS3/FAT4/VEGFC/EPHB4/TSPAN12/FZD4/PIEZO1/RRAS/CELSR1/NDP | 14 |
| BOSCO_TH1_CYTOTOXIC_MODULE | BOSCO_TH1_CYTOTOXIC_MODULE | BOSCO_TH1_CYTOTOXIC_MODULE | 19/1438 | 114/23056 | 0.1666667 | 2.672230 | 4.616226 | 0.0000780 | 0.0006512 | 0.0004186 | RUNX3/TNFSF18/STAB1/RTP4/TXK/IL15/ADAM19/SAMD3/IDO1/MYBL1/IL15RA/ANKRD22/KLRD1/TMEM229B/HAPLN3/RHBDF2/IL4I1/USP18/APOL3 | 19 |
| GOBP_MOLTING_CYCLE | GOBP_MOLTING_CYCLE | GOBP_MOLTING_CYCLE | 19/1438 | 114/23056 | 0.1666667 | 2.672230 | 4.616226 | 0.0000780 | 0.0006512 | 0.0004186 | PTCH2/PTGS2/TGFB2/WNT5A/FST/CD109/PDGFA/INHBA/SHH/FZD6/EXT1/NOTCH1/DKK1/FGFR2/ALX4/WNT10B/TNFRSF19/KRT17/SOX9 | 19 |
| SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | 37/1438 | 304/23056 | 0.1217105 | 1.951431 | 4.306838 | 0.0000784 | 0.0006542 | 0.0004206 | TNFRSF9/GBP1/FRRS1/FCGR2A/PRRX1/PTGS2/NID1/COL3A1/COL5A2/FN1/COL8A1/NPNT/IL15/DDX60/SPARC/ADAMTS2/PLA2G7/GJA1/TMEM200A/INHBA/SULF1/CD274/COL27A1/TNFSF15/COL5A1/PLAU/PAPSS2/ANKRD22/FAS/DRAM1/POSTN/NFKBIA/FBN1/COL1A1/EMILIN2/GATA6/PRNP | 37 |
| GOBP_REGULATION_OF_CELLULAR_COMPONENT_SIZE | GOBP_REGULATION_OF_CELLULAR_COMPONENT_SIZE | GOBP_REGULATION_OF_CELLULAR_COMPONENT_SIZE | 41/1438 | 350/23056 | 0.1171429 | 1.878196 | 4.269818 | 0.0000790 | 0.0006588 | 0.0004235 | CRABP2/LMOD1/CAPG/SCTR/FN1/SEMA3B/WNT5A/SLC12A8/SLIT2/SPP1/SLC12A7/SEMA5A/IL7R/F2RL1/EDN1/ARHGAP18/SCIN/AQP1/CCL26/SEMA3C/SEMA3A/SEMA3D/LMOD2/GSN/NRP1/EPS8/NCKAP1L/COTL1/TRPV2/CSF3/CCR7/SEMA6B/PEX11G/MAG/KCNN4/APOE/CDC42EP5/CDC42EP1/WNT7B/MSN/TENM1 | 41 |
| BIOCARTA_IL1R_PATHWAY | BIOCARTA_IL1R_PATHWAY | BIOCARTA_IL1R_PATHWAY | 9/1438 | 31/23056 | 0.2903226 | 4.654852 | 5.251763 | 0.0000802 | 0.0006673 | 0.0004290 | TGFB2/IL1R1/IL1A/IL1B/IRAK2/IL1RAP/IL6/NFKBIA/TGFB1 | 9 |
| GOBP_CHONDROCYTE_DEVELOPMENT | GOBP_CHONDROCYTE_DEVELOPMENT | GOBP_CHONDROCYTE_DEVELOPMENT | 9/1438 | 31/23056 | 0.2903226 | 4.654852 | 5.251763 | 0.0000802 | 0.0006673 | 0.0004290 | ECM1/TGFBR2/FGF18/RUNX2/SULF1/EXT1/COL27A1/SERPINH1/SOX9 | 9 |
| GOBP_REGULATION_OF_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | 9/1438 | 31/23056 | 0.2903226 | 4.654852 | 5.251763 | 0.0000802 | 0.0006673 | 0.0004290 | PPARG/WWTR1/VEPH1/DAB2/BMP6/RBPMS/BMP4/TGFB1/BMP2 | 9 |
| GOBP_REGULATION_OF_PROTEIN_IMPORT | GOBP_REGULATION_OF_PROTEIN_IMPORT | GOBP_REGULATION_OF_PROTEIN_IMPORT | 13/1438 | 61/23056 | 0.2131148 | 3.416950 | 4.874949 | 0.0000806 | 0.0006701 | 0.0004308 | ZC3H12A/PTGS2/GLI3/CD36/MDFIC/ARHGEF5/SHH/ANGPT1/BAG3/PRKD1/BMP4/JUP/TGFB1 | 13 |
| LEE_LIVER_CANCER_MYC_TGFA_UP | LEE_LIVER_CANCER_MYC_TGFA_UP | LEE_LIVER_CANCER_MYC_TGFA_UP | 13/1438 | 61/23056 | 0.2131148 | 3.416950 | 4.874949 | 0.0000806 | 0.0006701 | 0.0004308 | ELF3/CYP39A1/NT5E/PLAT/KRT8/IGFBP6/SERPINA6/ANXA2/MFGE8/MT2A/ICAM1/CNN1/USP18 | 13 |
| WP_VITAMIN_B12_METABOLISM | WP_VITAMIN_B12_METABOLISM | WP_VITAMIN_B12_METABOLISM | 12/1438 | 53/23056 | 0.2264151 | 3.630199 | 4.944115 | 0.0000808 | 0.0006717 | 0.0004318 | IL1B/SOD3/SOD2/IL6/SERPINE1/PLAT/NFKB2/SAA1/APOA1/CCL5/ICAM1/APOE | 12 |
| GOBP_PROTEIN_KINASE_B_SIGNALING | GOBP_PROTEIN_KINASE_B_SIGNALING | GOBP_PROTEIN_KINASE_B_SIGNALING | 29/1438 | 216/23056 | 0.1342593 | 2.152630 | 4.389579 | 0.0000811 | 0.0006733 | 0.0004328 | C1QTNF12/EPHA2/IL1B/KDR/EGF/SEMA5A/HBEGF/ADTRP/TPBG/PDGFA/MET/ANGPT1/TEK/AKR1C3/TCF7L2/PTPRJ/IGF1/ZFP36L1/THBS1/TNFAIP8L3/CCL5/CSF3/CCR7/SOX9/C1QTNF1/GDF15/AXL/TGFB1/RRAS | 29 |
| DORN_ADENOVIRUS_INFECTION_32HR_DN | DORN_ADENOVIRUS_INFECTION_32HR_DN | DORN_ADENOVIRUS_INFECTION_32HR_DN | 10/1438 | 38/23056 | 0.2631579 | 4.219310 | 5.122419 | 0.0000815 | 0.0006764 | 0.0004349 | EPHA2/CCN1/COL7A1/PLK2/ELL2/IER3/NFKB2/NFKBIA/TNFRSF12A/KRT19 | 10 |
| RIZ_ERYTHROID_DIFFERENTIATION_6HR | RIZ_ERYTHROID_DIFFERENTIATION_6HR | RIZ_ERYTHROID_DIFFERENTIATION_6HR | 10/1438 | 38/23056 | 0.2631579 | 4.219310 | 5.122419 | 0.0000815 | 0.0006764 | 0.0004349 | FOXC1/HOXA3/MYBL1/ANKRD1/HMGA2/TRPC4/SIX4/BNC1/HOXB3/SIM2 | 10 |
| ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | 18/1438 | 105/23056 | 0.1714286 | 2.748579 | 4.631626 | 0.0000819 | 0.0006782 | 0.0004360 | BHLHE40/PLAC8/VEGFC/GJA1/CITED2/SERPINE1/CAV1/LOXL2/STC1/ADM/GPRC5A/FOS/AHNAK2/LOXL1/KRT15/CAVIN1/SOX9/PDGFB | 18 |
| HP_HYPOPLASIA_OF_TEETH | HP_HYPOPLASIA_OF_TEETH | HP_HYPOPLASIA_OF_TEETH | 18/1438 | 105/23056 | 0.1714286 | 2.748579 | 4.631626 | 0.0000819 | 0.0006782 | 0.0004360 | LAMC2/LAMB3/TGFA/ITGB6/GALNT3/ITGA6/COL7A1/CLDN1/FGFR3/RUNX2/GJA1/FAM20C/FGFR2/MMP1/WNT10B/DLX3/KCNJ2/ITGB4 | 18 |
| GOBP_REGULATION_OF_LIPID_METABOLIC_PROCESS | GOBP_REGULATION_OF_LIPID_METABOLIC_PROCESS | GOBP_REGULATION_OF_LIPID_METABOLIC_PROCESS | 40/1438 | 339/23056 | 0.1179941 | 1.891844 | 4.266459 | 0.0000819 | 0.0006783 | 0.0004361 | LDLRAP1/CCN1/GFI1/PTGS2/AGT/IL1A/IL1B/PPARG/AADAC/FGFR3/DAB2/BMP6/ADGRF5/PDGFA/PDK4/CAV1/RARRES2/TEK/ANXA1/AKR1C3/ADM/RAB38/APOC3/APOA1/HCAR1/FLT3/FLT1/DNAJC15/PRKD1/TNFAIP8L3/LACTB/CES1/CCR7/GIP/SOX9/C3/TGFB1/APOE/BMP2/PDGFB | 40 |
| GOBP_T_CELL_DIFFERENTIATION_IN_THYMUS | GOBP_T_CELL_DIFFERENTIATION_IN_THYMUS | GOBP_T_CELL_DIFFERENTIATION_IN_THYMUS | 15/1438 | 78/23056 | 0.1923077 | 3.083342 | 4.753419 | 0.0000823 | 0.0006808 | 0.0004377 | MR1/PTPRC/ITPKB/IL1A/IL1B/IL7R/DOCK2/VNN1/GLI3/SHH/FZD8/TESPA1/BMP4/ZFP36L1/CCR7 | 15 |
| HP_CONTRACTURES_INVOLVING_THE_JOINTS_OF_THE_FEET | HP_CONTRACTURES_INVOLVING_THE_JOINTS_OF_THE_FEET | HP_CONTRACTURES_INVOLVING_THE_JOINTS_OF_THE_FEET | 15/1438 | 78/23056 | 0.1923077 | 3.083342 | 4.753419 | 0.0000823 | 0.0006808 | 0.0004377 | HSPG2/COL6A3/FGFR3/DSP/PSMB8/COL12A1/CCN2/GLI3/CAV1/FBN1/MMP2/JUP/SGCA/PIEZO2/COL6A2 | 15 |
| REACTOME_MUSCLE_CONTRACTION | REACTOME_MUSCLE_CONTRACTION | REACTOME_MUSCLE_CONTRACTION | 27/1438 | 195/23056 | 0.1384615 | 2.220006 | 4.412514 | 0.0000830 | 0.0006862 | 0.0004411 | CASQ1/LMOD1/ATP2B4/ACTG2/DES/KCNE4/TNNC1/MYLK/ITGB5/WWTR1/ITPR3/TRDN/MYL7/ASPH/TPM2/ANXA1/VCL/ACTC1/ANXA2/TPM1/MYH8/MYL4/KCNJ2/SCN1B/KCNK6/CACNG6/MYL9 | 27 |
| GOBP_PHAGOCYTOSIS | GOBP_PHAGOCYTOSIS | GOBP_PHAGOCYTOSIS | 37/1438 | 305/23056 | 0.1213115 | 1.945033 | 4.285000 | 0.0000840 | 0.0006936 | 0.0004459 | PTPRC/RAB7B/IL1B/SPON2/ANXA3/IL15/ITGA2/F2RL1/DOCK2/CD36/MET/MSR1/COLEC10/ANXA1/GSN/IL15RA/MBL2/SFTPD/PLPP4/PTPRJ/APOA1/NCKAP1L/RAB20/THBS1/MFGE8/PECAM1/COLEC12/ELANE/CNN2/C3/AXL/SIRPG/SIRPA/TGM2/MYH9/IL2RB/RAC2 | 37 |
| GOBP_MALE_SEX_DIFFERENTIATION | GOBP_MALE_SEX_DIFFERENTIATION | GOBP_MALE_SEX_DIFFERENTIATION | 24/1438 | 164/23056 | 0.1463415 | 2.346348 | 4.462639 | 0.0000842 | 0.0006948 | 0.0004467 | TGFB2/SRD5A2/IL1A/WNT5A/TLR3/BMP6/GJA1/CITED2/PDGFA/INHBA/SEMA3A/SHH/ZFPM2/AKR1C3/WT1/YBX3/MMP14/SIX4/SOX8/NUPR1/SOX9/GATA6/TFAP2C/COL9A3 | 24 |
| GOBP_REGULATION_OF_TISSUE_REMODELING | GOBP_REGULATION_OF_TISSUE_REMODELING | GOBP_REGULATION_OF_TISSUE_REMODELING | 16/1438 | 87/23056 | 0.1839080 | 2.948667 | 4.696568 | 0.0000847 | 0.0006966 | 0.0004478 | S1PR1/AGT/PPARG/SPP1/IL15/GJA1/TNFAIP3/IL6/GPNMB/PDK4/TNFRSF11B/UBASH3B/SIGLEC15/TNFRSF11A/TGFB1/RUNX1 | 16 |
| GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION | GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION | GOBP_REGULATION_OF_VIRAL_GENOME_REPLICATION | 16/1438 | 87/23056 | 0.1839080 | 2.948667 | 4.696568 | 0.0000847 | 0.0006966 | 0.0004478 | IFI16/RNASEL/NR5A2/CXCL8/TRIM38/PARP10/NOTCH1/IFITM2/IFITM3/HMGA2/OASL/CCL5/MX1/APOBEC3A/APOBEC3G/APOBEC3H | 16 |
| GOMF_BETA_CATENIN_BINDING | GOMF_BETA_CATENIN_BINDING | GOMF_BETA_CATENIN_BINDING | 16/1438 | 87/23056 | 0.1839080 | 2.948667 | 4.696568 | 0.0000847 | 0.0006966 | 0.0004478 | LEF1/SOX30/GJA1/PTPRK/GLI3/KLF4/VCL/TCF7L2/PTPRJ/BCL9L/GRIP1/TRPC4/FOXO1/DACT1/SALL1/SOX9 | 16 |
| GOMF_HORMONE_BINDING | GOMF_HORMONE_BINDING | GOMF_HORMONE_BINDING | 16/1438 | 87/23056 | 0.1839080 | 2.948667 | 4.696568 | 0.0000847 | 0.0006966 | 0.0004478 | ECE1/SCTR/THRB/VIPR1/UCN2/NPR3/CRHBP/HCRTR2/INHBA/NPY4R2/CCKBR/EDNRB/ALDH1A3/CDH13/GLP2R/EBI3 | 16 |
| SANA_RESPONSE_TO_IFNG_DN | SANA_RESPONSE_TO_IFNG_DN | SANA_RESPONSE_TO_IFNG_DN | 16/1438 | 87/23056 | 0.1839080 | 2.948667 | 4.696568 | 0.0000847 | 0.0006966 | 0.0004478 | RHOC/CD34/GASK1B/DAB2/GJA1/INHBA/DKK1/MICAL2/PRSS23/MMP10/VWF/ARHGDIB/KRT7/NQO1/COTL1/LGALS1 | 16 |
| HP_FACIAL_EDEMA | HP_FACIAL_EDEMA | HP_FACIAL_EDEMA | 21/1438 | 134/23056 | 0.1567164 | 2.512694 | 4.529304 | 0.0000847 | 0.0006966 | 0.0004478 | PTPN22/COL5A2/ADAMTS3/ARHGAP24/ADAMTS2/PSMB9/TMEM270/EPHB4/ANGPT1/GSN/CRB2/COL5A1/MYOF/WT1/TNFRSF1A/MYO1E/PIEZO1/COL1A1/RIN2/APOL1/TBC1D8B | 21 |
| GOBP_NEURAL_TUBE_DEVELOPMENT | GOBP_NEURAL_TUBE_DEVELOPMENT | GOBP_NEURAL_TUBE_DEVELOPMENT | 23/1438 | 154/23056 | 0.1493506 | 2.394596 | 4.478434 | 0.0000855 | 0.0007026 | 0.0004517 | EPHA2/RNF220/TGFB2/WNT5A/HES1/CITED2/GLI3/SEMA3C/FZD1/SHH/FZD6/CTHRC1/NOTCH1/ADM/BMP4/DACT1/ZFP36L1/ALDH1A2/FOXB1/NOG/TGFB1/SDC4/CELSR1 | 23 |
| GOBP_NIK_NF_KAPPAB_SIGNALING | GOBP_NIK_NF_KAPPAB_SIGNALING | GOBP_NIK_NF_KAPPAB_SIGNALING | 22/1438 | 144/23056 | 0.1527778 | 2.449544 | 4.500237 | 0.0000857 | 0.0007042 | 0.0004527 | ZC3H12A/PTPN22/IKBKE/NLRP3/IL1B/NMI/TLR3/EDN1/SASH1/TRIP6/TNFRSF10A/TCIM/TNFSF15/NFKB2/BIRC3/NFKBIA/UACA/IFI35/TNFSF14/BCL3/RELB/CARD10 | 22 |
| HP_CONGENITAL_MALFORMATION_OF_THE_GREAT_ARTERIES | HP_CONGENITAL_MALFORMATION_OF_THE_GREAT_ARTERIES | HP_CONGENITAL_MALFORMATION_OF_THE_GREAT_ARTERIES | 49/1438 | 446/23056 | 0.1098655 | 1.761515 | 4.188415 | 0.0000863 | 0.0007087 | 0.0004556 | MMP23B/ECE1/HSPG2/PTPN22/KCNN3/TGFB2/NID1/CFAP221/KYNU/TGFBR2/CD96/MYLK/FGFR3/DNAH5/MCIDAS/CCNO/PRDM6/FOXC1/RREB1/GJA1/CITED2/GLI3/PKD1L1/TMEM270/SAMD9/SHH/CSGALNACT1/ZFPM2/GAS1/NOTCH1/FGFR2/WT1/MYRF/ZIC2/MMP14/DACT1/FBN1/SALL1/MMP2/MAF/FOXF1/MYOCD/GATA6/BMP2/GATA5/COL18A1/USP18/ARSL/GPC4 | 49 |
| HP_ABNORMAL_STOMACH_MORPHOLOGY | HP_ABNORMAL_STOMACH_MORPHOLOGY | HP_ABNORMAL_STOMACH_MORPHOLOGY | 35/1438 | 283/23056 | 0.1236749 | 1.982927 | 4.291000 | 0.0000876 | 0.0007191 | 0.0004623 | MMP23B/HSPG2/PTCH2/LAMC2/PLA2G4A/LAMB3/IL1B/ITGA6/COL5A2/CASP10/MITF/FGFR3/ADAMTS3/FAT4/ADAMTS2/TFAP2A/TMEM270/PDGFRL/COL14A1/GLIS3/COL5A1/FAS/NFKB2/FGFR2/PTPRJ/EFEMP2/SERPINH1/FBLN5/CAVIN1/COL1A1/ITGB4/PIEZO2/COL18A1/FRMPD4/ARHGEF6 | 35 |
| KIM_WT1_TARGETS_12HR_DN | KIM_WT1_TARGETS_12HR_DN | KIM_WT1_TARGETS_12HR_DN | 29/1438 | 217/23056 | 0.1336406 | 2.142710 | 4.361958 | 0.0000881 | 0.0007225 | 0.0004645 | CCN1/LAMC2/PTPN7/CRIM1/ACKR3/TGFBR2/PLAC8/PLK2/FOXD1/HAPLN1/CCN2/SOD2/INHBA/SEMA3C/ASPH/EXT1/CD44/CASP4/NNMT/GPRC5A/AMIGO2/HMGA2/PLEK2/ZFP36L1/THBS1/BCL2A1/GADD45B/CYP24A1/IL2RB | 29 |
| GOMF_PEPTIDASE_REGULATOR_ACTIVITY | GOMF_PEPTIDASE_REGULATOR_ACTIVITY | GOMF_PEPTIDASE_REGULATOR_ACTIVITY | 30/1438 | 228/23056 | 0.1315789 | 2.109655 | 4.342860 | 0.0000895 | 0.0007336 | 0.0004716 | AGT/CRIM1/TFPI/FN1/SERPINE2/COL6A3/COL7A1/ITIH3/SERPINB1/CD109/SERPINE1/CAV1/CRB2/SERPINH1/BIRC3/CASP1/CARD16/SERPINE3/SERPINA10/SERPINA6/SERPINA1/ANXA2/SERPINB7/SERPINB2/SERPINB8/TNFSF14/C3/PRNP/WFDC10B/BIRC7 | 30 |
| HP_ABNORMAL_CRANIAL_NERVE_MORPHOLOGY | HP_ABNORMAL_CRANIAL_NERVE_MORPHOLOGY | HP_ABNORMAL_CRANIAL_NERVE_MORPHOLOGY | 33/1438 | 261/23056 | 0.1264368 | 2.027209 | 4.304409 | 0.0000899 | 0.0007358 | 0.0004730 | AGRN/PRRX1/DES/COL6A3/LAMB2/DOK7/OSMR/SH3TC2/TFAP2A/COL12A1/GJA1/LAMA2/GDF6/TPM2/GSN/DKK1/MYPN/COL13A1/BAG3/CRYAB/SIX1/MEOX1/ITGB4/TNFRSF11A/CACNA1A/TGFB1/SIX5/PRNP/COL6A2/PDGFB/FRMPD4/SRPX2/ARHGEF6 | 33 |
| REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION | 33/1438 | 261/23056 | 0.1264368 | 2.027209 | 4.304409 | 0.0000899 | 0.0007358 | 0.0004730 | ECM1/PLA2G4A/TGFB2/FN1/ITIH3/MGLL/EGF/TRPC3/VEGFC/SPARC/ITPR3/CD109/PDGFA/CD36/SERPINE1/RARRES2/CLU/TOR4A/APBB1IP/SRGN/VCL/APOA1/VWF/IGF1/SERPINA1/THBS1/LAT/GNGT2/COL1A1/PECAM1/TGFB1/RAC2/PDGFB | 33 |
| GOBP_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | 25/1438 | 175/23056 | 0.1428571 | 2.290483 | 4.419651 | 0.0000901 | 0.0007360 | 0.0004731 | TNFRSF1B/MR1/PTPRC/NLRP3/IL1R1/IL1B/CD96/BCL6/IL7R/HFE/HLA-E/MICA/RAET1E/AHR/IL6/KLRD1/KLRC4-KLRK1/NCKAP1L/STAT6/C3/IL27RA/IL12RB1/TGFB1/NECTIN2/IL4I1 | 25 |
| GOMF_PHOSPHATIDYLINOSITOL_PHOSPHATE_BINDING | GOMF_PHOSPHATIDYLINOSITOL_PHOSPHATE_BINDING | GOMF_PHOSPHATIDYLINOSITOL_PHOSPHATE_BINDING | 25/1438 | 175/23056 | 0.1428571 | 2.290483 | 4.419651 | 0.0000901 | 0.0007360 | 0.0004731 | LDLRAP1/PLA2G4A/CAPG/VEPH1/ZFYVE28/ARAP2/MYO10/IQGAP2/SCIN/GSDMD/GSN/ANXA8/PHLDA2/SYTL2/PHLDA1/TPCN1/PLEK2/ANXA2/GRAMD2A/ADAP2/WIPI1/KCNJ2/SDCBP2/JPH2/FRMPD4 | 25 |
| HP_ABNORMAL_URINE_PROTEIN_LEVEL | HP_ABNORMAL_URINE_PROTEIN_LEVEL | HP_ABNORMAL_URINE_PROTEIN_LEVEL | 31/1438 | 239/23056 | 0.1297071 | 2.079643 | 4.327173 | 0.0000902 | 0.0007360 | 0.0004731 | PTPN22/CFH/FN1/LAMB2/ARHGAP24/SPP1/CFI/TMEM270/SHH/GSN/CRB2/ITGA8/SAA1/WT1/APOA1/FLT1/ZIC2/SLC7A7/PYGL/MYO1E/MAF/ITGA3/C3/APOE/THBD/HMOX1/APOL1/MYH9/TBC1D8B/COL4A6/COL4A5 | 31 |
| MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 31/1438 | 239/23056 | 0.1297071 | 2.079643 | 4.327173 | 0.0000902 | 0.0007360 | 0.0004731 | PTPN14/RPRM/SERPINE2/BHLHE40/P3H2/ARAP2/PPP1R3G/IER3/CCN2/PERP/CAV1/PLEKHA2/PPP1R3C/IFITM3/HBD/ADM/LRRC32/TAGLN/VWF/BHLHE41/GRIP1/PHLDA1/ZIC2/CA12/MT1X/KRT19/DLX3/WIPI1/RHBDF2/SLC16A3/WTIP | 31 |
| YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN | 32/1438 | 250/23056 | 0.1280000 | 2.052273 | 4.314475 | 0.0000903 | 0.0007360 | 0.0004731 | TRIM63/TRIM17/SUSD5/SEMA3B/PCDH10/HAPLN1/ID4/SLC25A27/RHAG/COL12A1/SIM1/DDO/TRDN/ASB15/PAPPA/MYPN/HTR7/TRIM5/SLC5A12/EHF/PTPRJ/PYGM/HEPACAM/GRIP1/NPAS3/SERPINA1/MYH4/MYH1/SERPINB2/CKM/NCAM2/ELFN2 | 32 |
| FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN | FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN | FONTAINE_FOLLICULAR_THYROID_ADENOMA_DN | 14/1438 | 70/23056 | 0.2000000 | 3.206676 | 4.768811 | 0.0000904 | 0.0007360 | 0.0004731 | ECM1/S100A10/DPP4/IGSF10/CLDN1/GFPT2/CD274/KLF4/NOTCH1/CASP4/KLRD1/CLDN7/ABCA8/TENM1 | 14 |
| GOBP_NEURAL_RETINA_DEVELOPMENT | GOBP_NEURAL_RETINA_DEVELOPMENT | GOBP_NEURAL_RETINA_DEVELOPMENT | 14/1438 | 70/23056 | 0.2000000 | 3.206676 | 4.768811 | 0.0000904 | 0.0007360 | 0.0004731 | RPE65/IGFN1/ATP2B4/TGFB2/DLX1/DLX2/THRB/TFAP2A/TSPAN12/CRB2/CABP4/SOX8/LHX1/SOX9 | 14 |
| GOCC_CELL_CELL_CONTACT_ZONE | GOCC_CELL_CELL_CONTACT_ZONE | GOCC_CELL_CELL_CONTACT_ZONE | 14/1438 | 70/23056 | 0.2000000 | 3.206676 | 4.768811 | 0.0000904 | 0.0007360 | 0.0004731 | VAMP5/DES/FGFRL1/DSP/GJA1/VCL/AHNAK/KCNA5/MYH1/JUP/KCNJ2/DSG2/SCN1B/NECTIN2 | 14 |
| KEGG_VIRAL_MYOCARDITIS | KEGG_VIRAL_MYOCARDITIS | KEGG_VIRAL_MYOCARDITIS | 14/1438 | 70/23056 | 0.2000000 | 3.206676 | 4.768811 | 0.0000904 | 0.0007360 | 0.0004731 | CASP8/HLA-E/HLA-C/LAMA2/CAV1/MYH13/MYH8/MYH4/MYH1/MYH2/SGCA/ICAM1/MYH9/RAC2 | 14 |
| HP_ABNORMALITY_OF_DENTAL_STRUCTURE | HP_ABNORMALITY_OF_DENTAL_STRUCTURE | HP_ABNORMALITY_OF_DENTAL_STRUCTURE | 39/1438 | 329/23056 | 0.1185410 | 1.900613 | 4.243455 | 0.0000905 | 0.0007364 | 0.0004734 | PTCH2/LAMC2/LAMB3/TGFA/ITGB6/GALNT3/ITGA6/COL3A1/COL5A2/IL17RC/COL7A1/CLDN1/FGFR3/AMTN/ENAM/SGMS2/RREB1/RUNX2/TENT5A/GJA1/CCN2/PERP/FAM20C/TMEM270/CAV1/TRPS1/COL5A1/FGFR2/SERPINH1/MMP1/WNT10B/SLC24A4/DLX3/COL1A1/KCNJ2/ITGB4/TNFRSF11A/ELANE/TGFB1 | 39 |
| HP_ABNORMAL_STERNUM_MORPHOLOGY | HP_ABNORMAL_STERNUM_MORPHOLOGY | HP_ABNORMAL_STERNUM_MORPHOLOGY | 46/1438 | 411/23056 | 0.1119221 | 1.794490 | 4.191578 | 0.0000906 | 0.0007372 | 0.0004739 | AGRN/HSPG2/PTCH2/TGFB2/COL3A1/FN1/TGFBR2/WNT5A/CD96/MYLK/MME/FGFRL1/FGFR3/COL12A1/TENT5A/FAM20C/TMEM270/MET/CSGALNACT1/ZFPM2/TRPS1/TNFRSF11B/TPM2/COL5A1/MYPN/COL13A1/EFEMP2/ITGA7/DACT1/LTBP2/FBLN5/FBN1/MAF/PIEZO1/RNF135/NOG/SOX9/PIEZO2/GATA6/TNFRSF11A/RRAS/BMP2/RIN2/SRPX2/GPC4/BGN | 46 |
| MISSIAGLIA_REGULATED_BY_METHYLATION_UP | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | MISSIAGLIA_REGULATED_BY_METHYLATION_UP | 20/1438 | 125/23056 | 0.1600000 | 2.565341 | 4.525918 | 0.0000922 | 0.0007493 | 0.0004817 | IFI44L/PTGS2/IL1B/SP110/ITGA2/HLA-E/TNFAIP3/PERP/SOD2/SERPINE1/PLAT/GSN/BIRC3/TNFAIP2/MFGE8/IL32/COL1A1/SDC4/MX2/SAT1 | 20 |
| GOBP_MACROPHAGE_ACTIVATION | GOBP_MACROPHAGE_ACTIVATION | GOBP_MACROPHAGE_ACTIVATION | 18/1438 | 106/23056 | 0.1698113 | 2.722649 | 4.584719 | 0.0000929 | 0.0007537 | 0.0004846 | ZC3H12A/EDN2/PLA2G4A/PTPRC/NMI/WNT5A/SUCNR1/TLR3/IL31RA/CSF2/ADGRF5/IL6/CLU/LRFN5/THBS1/IL4R/IFI35/C5AR1 | 18 |
| GOBP_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | 8/1438 | 25/23056 | 0.3200000 | 5.130681 | 5.329538 | 0.0000932 | 0.0007537 | 0.0004846 | RUNX3/ZC3H12A/BCL6/GLI3/SHH/ANXA1/IL4R/RUNX1 | 8 |
| GOBP_PLASMINOGEN_ACTIVATION | GOBP_PLASMINOGEN_ACTIVATION | GOBP_PLASMINOGEN_ACTIVATION | 8/1438 | 25/23056 | 0.3200000 | 5.130681 | 5.329538 | 0.0000932 | 0.0007537 | 0.0004846 | S100A10/SERPINE2/SERPINE1/PLAT/PLAU/THBS1/ANXA2/RUNX1 | 8 |
| GOBP_SUBSTRATE_DEPENDENT_CELL_MIGRATION | GOBP_SUBSTRATE_DEPENDENT_CELL_MIGRATION | GOBP_SUBSTRATE_DEPENDENT_CELL_MIGRATION | 8/1438 | 25/23056 | 0.3200000 | 5.130681 | 5.329538 | 0.0000932 | 0.0007537 | 0.0004846 | PTPRC/FN1/SLIT2/VEGFC/ITGA2/NRP1/ITGA11/CSPG4 | 8 |
| GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_SINGLE_DONORS_WITH_INCORPORATION_OF_MOLECULAR_OXYGEN | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_SINGLE_DONORS_WITH_INCORPORATION_OF_MOLECULAR_OXYGEN | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_SINGLE_DONORS_WITH_INCORPORATION_OF_MOLECULAR_OXYGEN | 8/1438 | 25/23056 | 0.3200000 | 5.130681 | 5.329538 | 0.0000932 | 0.0007537 | 0.0004846 | RPE65/PTGS2/TDO2/IDO1/PTGS1/ALOX5/HPD/ALOX5AP | 8 |
| OLSSON_E2F3_TARGETS_UP | OLSSON_E2F3_TARGETS_UP | OLSSON_E2F3_TARGETS_UP | 8/1438 | 25/23056 | 0.3200000 | 5.130681 | 5.329538 | 0.0000932 | 0.0007537 | 0.0004846 | ECE1/ELF3/TENT5A/LAMA4/AKR1C3/SERPINH1/TNFAIP2/CA12 | 8 |
| WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE | WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE | WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE | 8/1438 | 25/23056 | 0.3200000 | 5.130681 | 5.329538 | 0.0000932 | 0.0007537 | 0.0004846 | HSPB7/PPARG/PLAC8/MPZL2/BMP4/SLC7A10/BMP2/CEBPB | 8 |
| WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE | WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE | WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE | 8/1438 | 25/23056 | 0.3200000 | 5.130681 | 5.329538 | 0.0000932 | 0.0007537 | 0.0004846 | LTBP1/TGFBR2/RUNX2/CCN2/SERPINE1/POSTN/LTBP2/FBN1 | 8 |
| GOBP_CELL_CELL_JUNCTION_ORGANIZATION | GOBP_CELL_CELL_JUNCTION_ORGANIZATION | GOBP_CELL_CELL_JUNCTION_ORGANIZATION | 28/1438 | 207/23056 | 0.1352657 | 2.168766 | 4.356458 | 0.0000936 | 0.0007537 | 0.0004846 | EPHA2/RHOC/TGFB2/AGT/IL1B/XIRP2/EPHA4/HEG1/CLDN1/CLDN16/CDH9/F2RL1/DSP/BMP6/GJA1/PERP/MICALL2/CAV1/ZNF703/EXT1/VCL/CLDN6/KIFC3/CLDN7/JUP/PECAM1/DSG2/TGFB1 | 28 |
| GOBP_KIDNEY_MESENCHYME_DEVELOPMENT | GOBP_KIDNEY_MESENCHYME_DEVELOPMENT | GOBP_KIDNEY_MESENCHYME_DEVELOPMENT | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | OSR1/FOXD1/SHH/WT1/BMP4/SIX1/SIX4 | 7 |
| GOBP_NEGATIVE_REGULATION_OF_MIRNA_TRANSCRIPTION | GOBP_NEGATIVE_REGULATION_OF_MIRNA_TRANSCRIPTION | GOBP_NEGATIVE_REGULATION_OF_MIRNA_TRANSCRIPTION | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | PPARG/NFATC4/BMP4/SOX9/GATA6/TGFB1/PDGFB | 7 |
| GOBP_POSITIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | FGF18/BMP6/RUNX2/GLI3/LOXL2/GDF6/SOX9 | 7 |
| GOBP_REGULATION_OF_CD8_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_REGULATION_OF_CD8_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_REGULATION_OF_CD8_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | RUNX3/PTPN22/HFE/HLA-E/CD274/NCKAP1L/RUNX1 | 7 |
| GOBP_RESPONSE_TO_HYPEROXIA | GOBP_RESPONSE_TO_HYPEROXIA | GOBP_RESPONSE_TO_HYPEROXIA | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | SOD2/CAV1/FAS/KCNA5/FOXO1/MMP2/COL1A1 | 7 |
| HP_MILIA | HP_MILIA | HP_MILIA | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | PTCH2/LAMC2/LAMB3/ITGA6/COL7A1/MMP1/ITGB4 | 7 |
| UROSEVIC_RESPONSE_TO_IMIQUIMOD | UROSEVIC_RESPONSE_TO_IMIQUIMOD | UROSEVIC_RESPONSE_TO_IMIQUIMOD | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | MICB/IL6/IDO1/PLAAT4/OASL/IFI35/MX1 | 7 |
| WP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS | WP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS | WP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS | 7/1438 | 19/23056 | 0.3684211 | 5.907035 | 5.518705 | 0.0000937 | 0.0007537 | 0.0004846 | COL3A1/FN1/SPARC/THBS2/COL5A1/YAP1/COL1A1 | 7 |
| GOBP_TRABECULA_MORPHOGENESIS | GOBP_TRABECULA_MORPHOGENESIS | GOBP_TRABECULA_MORPHOGENESIS | 11/1438 | 46/23056 | 0.2391304 | 3.834069 | 4.962326 | 0.0000939 | 0.0007550 | 0.0004854 | S1PR1/TGFB2/BMP10/HEG1/ADGRG6/TEK/NOTCH1/WNT10B/MMP2/COL1A1/NOG | 11 |
| HP_DENTAL_MALOCCLUSION | HP_DENTAL_MALOCCLUSION | HP_DENTAL_MALOCCLUSION | 21/1438 | 135/23056 | 0.1555556 | 2.494081 | 4.490333 | 0.0000945 | 0.0007595 | 0.0004882 | HSPG2/KCNN3/TGFA/ITGB6/FGFR3/ENAM/FAT4/EDN1/TENT5A/GJA1/TMEM270/ASPH/TRPS1/FGFR2/WNT10B/GRIP1/FREM2/BMP4/DLX4/BMP2/GPC4 | 21 |
| MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | MCBRYAN_PUBERTAL_BREAST_6_7WK_DN | 15/1438 | 79/23056 | 0.1898734 | 3.044313 | 4.694274 | 0.0000958 | 0.0007698 | 0.0004949 | FBLIM1/ACTG2/BCL6/SLC4A4/DSP/PLA2G7/UTRN/EHF/TAGLN/EPS8/TNFRSF12A/ACSM3/MT1X/MBP/CNN1 | 15 |
| TENEDINI_MEGAKARYOCYTE_MARKERS | TENEDINI_MEGAKARYOCYTE_MARKERS | TENEDINI_MEGAKARYOCYTE_MARKERS | 13/1438 | 62/23056 | 0.2096774 | 3.361838 | 4.802782 | 0.0000962 | 0.0007724 | 0.0004965 | IL1R1/IL1B/CXCL8/CXCL1/PDGFC/PDGFA/IL6/NFE2/FOS/CCL5/TGFB1/IL11/PDGFB | 13 |
| VECCHI_GASTRIC_CANCER_EARLY_UP | VECCHI_GASTRIC_CANCER_EARLY_UP | VECCHI_GASTRIC_CANCER_EARLY_UP | 48/1438 | 436/23056 | 0.1100917 | 1.765143 | 4.160003 | 0.0000965 | 0.0007743 | 0.0004978 | PDZK1IP1/CTSS/S100A10/S100A11/LAMC2/TMEM158/COL7A1/MUC13/TM4SF1/CLDN1/CXCL8/CXCL1/CXCL5/CXCL3/SPP1/ITGA2/ATP10B/TFAP2A/PSMB8/SOD2/MACC1/INHBA/ZNF703/FBXO32/EPPK1/IL15RA/AIFM2/MYOF/IFITM2/IFITM3/FOSL1/MYEOV/MMP3/GPRC5A/KRT7/KRT18/ZIC2/AJUBA/CRIP1/PIEZO1/CLDN7/JUP/GDF15/KCNN4/KLK6/TFAP2C/RUNX1/LIF | 48 |
| RUTELLA_RESPONSE_TO_HGF_DN | RUTELLA_RESPONSE_TO_HGF_DN | RUTELLA_RESPONSE_TO_HGF_DN | 31/1438 | 240/23056 | 0.1291667 | 2.070978 | 4.301508 | 0.0000975 | 0.0007818 | 0.0005026 | RUNX3/NLRP3/ITGA4/SP110/LPP/EREG/PLAC8/IQGAP2/F2RL1/HBEGF/CCDC69/ADAM19/HLA-E/ALOX5/TCF7L2/IFITM2/MS4A4A/PLAAT4/CASP1/SLC7A7/CRIP1/PECAM1/SLC16A5/GADD45B/ZFP36/C5AR1/FPR1/MX2/IL13RA1/ARHGEF6/ZNF185 | 31 |
| GOBP_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | 16/1438 | 88/23056 | 0.1818182 | 2.915160 | 4.642362 | 0.0000976 | 0.0007818 | 0.0005026 | TNFRSF1B/MR1/PTPRC/NLRP3/IL1R1/IL1B/IL7R/HFE/HLA-E/AHR/IL6/KLRD1/NCKAP1L/IL12RB1/NECTIN2/IL4I1 | 16 |
| DEMAGALHAES_AGING_UP | DEMAGALHAES_AGING_UP | DEMAGALHAES_AGING_UP | 12/1438 | 54/23056 | 0.2222222 | 3.562973 | 4.863091 | 0.0000981 | 0.0007846 | 0.0005044 | GBP2/CTSS/FCGR2A/EFEMP1/JCHAIN/ANXA3/SPP1/GPNMB/CLU/VWF/C3/MSN | 12 |
| GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | 12/1438 | 54/23056 | 0.2222222 | 3.562973 | 4.863091 | 0.0000981 | 0.0007846 | 0.0005044 | KDR/SEMA5A/TNFAIP3/SERPINE1/ANGPT1/TEK/TCF7L2/YAP1/NUPR1/ICAM1/IL11/HMOX1 | 12 |
| GOBP_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 12/1438 | 54/23056 | 0.2222222 | 3.562973 | 4.863091 | 0.0000981 | 0.0007846 | 0.0005044 | BMP10/CYP26B1/EDN1/RBM24/SHH/IGF1/MMP14/BMP4/MYLK3/PIEZO1/MYOCD/TGFB1 | 12 |
| GOBP_REGULATION_OF_PROTEIN_BINDING | GOBP_REGULATION_OF_PROTEIN_BINDING | GOBP_REGULATION_OF_PROTEIN_BINDING | 27/1438 | 197/23056 | 0.1370558 | 2.197468 | 4.353342 | 0.0000989 | 0.0007911 | 0.0005086 | LDLRAP1/ITGA4/XIRP1/WNT5A/DAB2/STING1/ADRB2/HFE/CAV1/CTHRC1/ANGPT1/NRP1/DKK1/TCF7L2/PHLDA2/CARD16/UBASH3B/NFATC4/BMP4/DACT1/ANXA2/CSF3/NOG/TMC8/APOE/BMP2/PDGFB | 27 |
| GOBP_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION | GOBP_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION | GOBP_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION | 19/1438 | 116/23056 | 0.1637931 | 2.626157 | 4.528444 | 0.0000992 | 0.0007928 | 0.0005097 | CSF1/ECM1/ITGA4/WNT5A/SLIT2/ADTRP/PLA2G7/SERPINE1/RARRES2/C3AR1/KLRC4-KLRK1/THBS1/CCL5/CCR7/TNFSF14/IL27RA/C5AR1/DEFB124/MSN | 19 |
| GOMF_G_PROTEIN_COUPLED_RECEPTOR_BINDING | GOMF_G_PROTEIN_COUPLED_RECEPTOR_BINDING | GOMF_G_PROTEIN_COUPLED_RECEPTOR_BINDING | 35/1438 | 285/23056 | 0.1228070 | 1.969011 | 4.245361 | 0.0001010 | 0.0008063 | 0.0005183 | EDN2/PTCH2/S1PR1/WNT9A/AGT/RTP3/UCN2/WNT5A/RTP4/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/EDN1/RSPO3/CCL26/FZD1/PNOC/CTHRC1/CCKBR/ADM/SAA1/WNT10B/EDNRB/CCL5/GIP/ITGB4/C3/FPR1/PRNP/CLIC6/WNT7B/NDP | 35 |
| WIERENGA_STAT5A_TARGETS_GROUP1 | WIERENGA_STAT5A_TARGETS_GROUP1 | WIERENGA_STAT5A_TARGETS_GROUP1 | 20/1438 | 126/23056 | 0.1587302 | 2.544981 | 4.484981 | 0.0001033 | 0.0008241 | 0.0005298 | TNFRSF4/DHRS3/GBP4/CFH/XIRP1/FNDC3B/GPAT3/MYO10/DAB2/ITGA2/F2RL1/RHAG/ADM/PHLDA1/TNFAIP8L3/IL4R/PLVAP/IL4I1/TGM2/A4GALT | 20 |
| DORN_ADENOVIRUS_INFECTION_48HR_DN | DORN_ADENOVIRUS_INFECTION_48HR_DN | DORN_ADENOVIRUS_INFECTION_48HR_DN | 10/1438 | 39/23056 | 0.2564103 | 4.111123 | 5.015097 | 0.0001036 | 0.0008248 | 0.0005302 | EPHA2/CCN1/COL7A1/PLK2/ELL2/IER3/IL6/NFKBIA/TNFRSF12A/KRT19 | 10 |
| GOBP_FOAM_CELL_DIFFERENTIATION | GOBP_FOAM_CELL_DIFFERENTIATION | GOBP_FOAM_CELL_DIFFERENTIATION | 10/1438 | 39/23056 | 0.2564103 | 4.111123 | 5.015097 | 0.0001036 | 0.0008248 | 0.0005302 | CSF1/AGT/PPARG/CSF2/CD36/MSR1/SOAT2/NFKBIA/CETP/TGFB1 | 10 |
| HAN_JNK_SINGALING_DN | HAN_JNK_SINGALING_DN | HAN_JNK_SINGALING_DN | 10/1438 | 39/23056 | 0.2564103 | 4.111123 | 5.015097 | 0.0001036 | 0.0008248 | 0.0005302 | HSD11B1/SOD3/AHR/SEMA3C/HAS2/ANXA8L1/FAS/SOCS3/C3/COL6A2 | 10 |
| OLSSON_E2F3_TARGETS_DN | OLSSON_E2F3_TARGETS_DN | OLSSON_E2F3_TARGETS_DN | 10/1438 | 39/23056 | 0.2564103 | 4.111123 | 5.015097 | 0.0001036 | 0.0008248 | 0.0005302 | CXCL1/FST/H3C6/INHBA/CAV2/KRT80/NFKBIA/THBS1/MT1X/THBD | 10 |
| HP_ARTHRALGIA | HP_ARTHRALGIA | HP_ARTHRALGIA | 26/1438 | 187/23056 | 0.1390374 | 2.229240 | 4.352995 | 0.0001040 | 0.0008275 | 0.0005320 | LDLRAP1/PTPN22/NLRP3/COL5A2/SLCO2A1/SPP1/STING1/HFE/PSMB8/PSMB9/TENT5A/CCN2/IL6/TMEM270/CAV1/TRPS1/TNFRSF11B/COL5A1/FAS/NFKB2/TNFRSF1A/C1S/MMP2/COL1A1/RUNX1/IL2RB | 26 |
| GOBP_CARDIOCYTE_DIFFERENTIATION | GOBP_CARDIOCYTE_DIFFERENTIATION | GOBP_CARDIOCYTE_DIFFERENTIATION | 23/1438 | 156/23056 | 0.1474359 | 2.363896 | 4.408390 | 0.0001045 | 0.0008308 | 0.0005341 | VCAM1/TGFB2/AGT/BMP10/RARB/HES1/EDN1/TBX18/CITED2/SEMA3C/NOTCH1/DKK1/WT1/IGF1/BMP4/ACTC1/ALPK3/MYLK3/MYOCD/GATA6/ALPK2/TGFB1/BMP2 | 23 |
| HELLER_SILENCED_BY_METHYLATION_DN | HELLER_SILENCED_BY_METHYLATION_DN | HELLER_SILENCED_BY_METHYLATION_DN | 18/1438 | 107/23056 | 0.1682243 | 2.697204 | 4.538354 | 0.0001053 | 0.0008358 | 0.0005373 | NIBAN1/PTPRC/JCHAIN/CDS1/SLC7A11/F2RL1/ADRB2/RCAN2/BAG3/SERPINH1/DNAJC15/THBS1/MAF/OSGIN1/SLC47A1/GDF15/CEBPB/HMOX1 | 18 |
| GOBP_HEART_FORMATION | GOBP_HEART_FORMATION | GOBP_HEART_FORMATION | 9/1438 | 32/23056 | 0.2812500 | 4.509388 | 5.123541 | 0.0001054 | 0.0008358 | 0.0005373 | WNT5A/HES1/EXT1/NOTCH1/DKK1/BMP4/SIX1/BMP2/GATA5 | 9 |
| GOBP_PROSTANOID_BIOSYNTHETIC_PROCESS | GOBP_PROSTANOID_BIOSYNTHETIC_PROCESS | GOBP_PROSTANOID_BIOSYNTHETIC_PROCESS | 9/1438 | 32/23056 | 0.2812500 | 4.509388 | 5.123541 | 0.0001054 | 0.0008358 | 0.0005373 | EDN2/PTGS2/PLA2G4A/IL1B/EDN1/ANXA1/PTGS1/AKR1C3/PTGIS | 9 |
| PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP | PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP | PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP | 9/1438 | 32/23056 | 0.2812500 | 4.509388 | 5.123541 | 0.0001054 | 0.0008358 | 0.0005373 | RPE65/IL1B/CXCL2/TLR3/PTN/CEBPD/HTR7/GLP2R/PLS3 | 9 |
| WP_ANTIVIRAL_AND_ANTIINFLAMMATORY_EFFECTS_OF_NRF2_ON_SARSCOV2_PATHWAY | WP_ANTIVIRAL_AND_ANTIINFLAMMATORY_EFFECTS_OF_NRF2_ON_SARSCOV2_PATHWAY | WP_ANTIVIRAL_AND_ANTIINFLAMMATORY_EFFECTS_OF_NRF2_ON_SARSCOV2_PATHWAY | 9/1438 | 32/23056 | 0.2812500 | 4.509388 | 5.123541 | 0.0001054 | 0.0008358 | 0.0005373 | IL1B/CXCL8/SLC7A11/IL6/MMP1/MMP3/NFKBIA/NQO1/HMOX1 | 9 |
| GOBP_REGULATION_OF_MUSCLE_HYPERTROPHY | GOBP_REGULATION_OF_MUSCLE_HYPERTROPHY | GOBP_REGULATION_OF_MUSCLE_HYPERTROPHY | 14/1438 | 71/23056 | 0.1971831 | 3.161512 | 4.704557 | 0.0001062 | 0.0008403 | 0.0005402 | ERRFI1/TNFRSF1B/TRIM63/ATP2B4/AGT/BMP10/PPARG/TRPC3/EDN1/NOTCH1/TNFRSF1A/IGF1/FOXO1/GATA5 | 14 |
| HP_PLEURAL_EFFUSION | HP_PLEURAL_EFFUSION | HP_PLEURAL_EFFUSION | 14/1438 | 71/23056 | 0.1971831 | 3.161512 | 4.704557 | 0.0001062 | 0.0008403 | 0.0005402 | CFH/BCL6/ADAMTS3/SPP1/CFI/FAT4/HFE/IL6/EPHB4/FAS/FOXF1/PIEZO1/PLVAP/BMP2 | 14 |
| REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | 14/1438 | 71/23056 | 0.1971831 | 3.161512 | 4.704557 | 0.0001062 | 0.0008403 | 0.0005402 | GBP2/RNASEL/HLA-E/HLA-C/PSMB8/IFITM2/IFITM3/OASL/IRF9/IFI35/SOCS3/MX2/MX1/USP18 | 14 |
| SATOH_COLORECTAL_CANCER_MYC_DN | SATOH_COLORECTAL_CANCER_MYC_DN | SATOH_COLORECTAL_CANCER_MYC_DN | 14/1438 | 71/23056 | 0.1971831 | 3.161512 | 4.704557 | 0.0001062 | 0.0008403 | 0.0005402 | DHRS3/FUCA1/SLCO2A1/SLC4A4/CDS1/CD36/PAPSS2/FAS/SLC16A12/SLC22A18AS/SLC22A18/TNFRSF1A/SLC46A3/LDHD | 14 |
| GOBP_CELL_GROWTH | GOBP_CELL_GROWTH | GOBP_CELL_GROWTH | 52/1438 | 487/23056 | 0.1067762 | 1.711983 | 4.095739 | 0.0001108 | 0.0008764 | 0.0005634 | CDA/EDN2/PTCH2/CRABP2/TGFB2/AGT/BMP10/ITGA4/NRP2/FN1/SERPINE2/TGFBR2/LAMB2/SEMA3B/WNT5A/FOXL2/BCL6/OSTN/SLIT2/SPP1/SEMA5A/DAB2/HBEGF/EDN1/DDR1/ROS1/GJA1/INHBA/SEMA3C/SEMA3A/SEMA3D/EXT1/NRP1/VCL/WT1/PTPRJ/YAP1/CRYAB/IGF1/MMP14/FBLN5/BDKRB1/OSGIN1/MYOCD/TRPV2/KRT17/SOX9/TMC8/SEMA6B/MAG/TGFB1/APOE | 52 |
| GOBP_HYALURONAN_BIOSYNTHETIC_PROCESS | GOBP_HYALURONAN_BIOSYNTHETIC_PROCESS | GOBP_HYALURONAN_BIOSYNTHETIC_PROCESS | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | IL1B/EGF/HAS2/TGFB1/HAS1/PDGFB | 6 |
| GOBP_PROTEIN_OXIDATION | GOBP_PROTEIN_OXIDATION | GOBP_PROTEIN_OXIDATION | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | TRABD2B/TRABD2A/LOXL2/LOXL4/APOA1/LOXL1 | 6 |
| GOBP_REGULATION_OF_GONAD_DEVELOPMENT | GOBP_REGULATION_OF_GONAD_DEVELOPMENT | GOBP_REGULATION_OF_GONAD_DEVELOPMENT | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | CITED2/SEMA3A/ZFPM2/WT1/NUPR1/SOX9 | 6 |
| GOMF_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING | GOMF_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING | GOMF_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | IL1R1/PDGFC/PDGFA/PTPRJ/ITGA5/PDGFB | 6 |
| GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3 | GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3 | GRANDVAUX_IFN_RESPONSE_NOT_VIA_IRF3 | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | GBP2/IFITM3/IRF9/IFI35/MX2/MX1 | 6 |
| HP_CAMPTODACTYLY_OF_TOE | HP_CAMPTODACTYLY_OF_TOE | HP_CAMPTODACTYLY_OF_TOE | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | FGFR3/DSP/GLI3/MMP2/JUP/PIEZO2 | 6 |
| REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | TGFA/EPGN/EREG/BTC/EGF/HBEGF | 6 |
| ROETH_TERT_TARGETS_UP | ROETH_TERT_TARGETS_UP | ROETH_TERT_TARGETS_UP | 6/1438 | 14/23056 | 0.4285714 | 6.871448 | 5.667655 | 0.0001132 | 0.0008910 | 0.0005728 | IFI44L/PLA2G4A/HEG1/SLC12A8/OASL/MX1 | 6 |
| GOBP_NEGATIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | GOBP_NEGATIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | GOBP_NEGATIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | 13/1438 | 63/23056 | 0.2063492 | 3.308475 | 4.732078 | 0.0001144 | 0.0008998 | 0.0005785 | IL1A/WNT5A/GJA1/PLAT/SULF1/ZFPM2/PAEP/WT1/ARHGDIB/IGF1/BMP4/LIF/MYH9 | 13 |
| GOBP_OLEFINIC_COMPOUND_METABOLIC_PROCESS | GOBP_OLEFINIC_COMPOUND_METABOLIC_PROCESS | GOBP_OLEFINIC_COMPOUND_METABOLIC_PROCESS | 23/1438 | 157/23056 | 0.1464968 | 2.348839 | 4.373770 | 0.0001153 | 0.0009065 | 0.0005827 | DHRS3/RPE65/PTGS2/PLA2G4A/SRD5A2/MGLL/DAB2/BMP6/AKR1B10/AKR1B15/PTGS1/AKR1C3/ALOX5/ADM/EDNRB/CYP46A1/CYP19A1/ALDH1A2/ALDH1A3/CYP4F11/PLA2G4C/BMP2/PTGIS | 23 |
| KIM_WT1_TARGETS_8HR_DN | KIM_WT1_TARGETS_8HR_DN | KIM_WT1_TARGETS_8HR_DN | 20/1438 | 127/23056 | 0.1574803 | 2.524942 | 4.444437 | 0.0001155 | 0.0009075 | 0.0005834 | LAX1/TGFB2/KYNU/ACKR3/PLAC8/FST/PLK2/F2RL1/CCN2/CITED2/SOD2/SEMA3C/MSR1/ASPH/CASP1/NNMT/GPRC5A/AMIGO2/DACT1/MID1 | 20 |
| GOBP_LABYRINTHINE_LAYER_DEVELOPMENT | GOBP_LABYRINTHINE_LAYER_DEVELOPMENT | GOBP_LABYRINTHINE_LAYER_DEVELOPMENT | 11/1438 | 47/23056 | 0.2340426 | 3.752493 | 4.871700 | 0.0001157 | 0.0009083 | 0.0005839 | CCN1/CASP8/HES1/LEF1/GCM1/RSPO3/FGFR2/ADM/ZFP36L1/SOCS3/WNT7B | 11 |
| TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP | 11/1438 | 47/23056 | 0.2340426 | 3.752493 | 4.871700 | 0.0001157 | 0.0009083 | 0.0005839 | COL3A1/COL5A2/FN1/LRRC15/DDX60/SULF1/CD44/LUM/POSTN/FBN1/COL1A1 | 11 |
| GOBP_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | GOBP_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | GOBP_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 22/1438 | 147/23056 | 0.1496599 | 2.399553 | 4.390352 | 0.0001170 | 0.0009177 | 0.0005900 | SOD3/EDN1/PTPRK/TNFAIP3/SOD2/IL6/AQP1/CD36/MET/GPR37/TRPA1/ANXA1/AKR1C3/STAT6/FOS/FBLN5/TPM1/MMP2/NQO1/KLF2/AXL/SIRPA | 22 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 12/1438 | 55/23056 | 0.2181818 | 3.498192 | 4.783965 | 0.0001184 | 0.0009282 | 0.0005967 | AGT/TGFA/EPHA4/DOK7/EPGN/EREG/BTC/EGF/HBEGF/CCL5/PRNP/PDGFB | 12 |
| GOBP_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | GOBP_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | GOBP_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY | 33/1438 | 265/23056 | 0.1245283 | 1.996609 | 4.208434 | 0.0001206 | 0.0009447 | 0.0006073 | DHRS3/PTPN22/NR5A2/LBH/CYP26B1/PPARG/THRB/RARB/DDX60/AHRR/DAB2/ZNF366/TNFAIP3/CITED2/AHR/DDX58/AKR1C3/CYP26A1/SLC15A3/PGR/YAP1/BIRC3/OASL/NFKBIA/ESRRB/ALDH1A2/RNF135/DHX58/KLF2/BMP2/PTGIS/CYP24A1/MN1 | 33 |
| TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 38/1438 | 322/23056 | 0.1180124 | 1.892138 | 4.157921 | 0.0001215 | 0.0009516 | 0.0006118 | RUNX3/PTPRC/RASSF5/CD34/PTPN14/LTBP1/CAPG/CAVIN2/PLAC8/IL31RA/IQGAP2/ELL2/SH3TC2/CCDC69/DOCK2/PSMB8/PSMB9/FUCA2/TNS3/TPK1/ANGPT1/PTPN3/PTGR1/JCAD/SLC6A13/NCKAP1L/HMGA2/SELPLG/LATS2/LCP1/NLRC5/SMIM36/CNN2/GMFG/TGM2/LGALS1/ITM2A/DACH2 | 38 |
| HP_PNEUMONIA | HP_PNEUMONIA | HP_PNEUMONIA | 32/1438 | 254/23056 | 0.1259843 | 2.019953 | 4.215654 | 0.0001220 | 0.0009550 | 0.0006139 | GFI1/FCGR2A/FMO3/LAMC2/PTPRC/LAMB3/CASP8/SP110/IL7R/MCIDAS/CITED2/SAMD9/SHH/TPM2/GAS1/NFKB2/EFEMP2/SCNN1A/ITGA7/ZIC2/FBLN5/ACTC1/IL21R/LAT/GATA6/TNFRSF11A/ELANE/IL12RB1/TGFB1/RAC2/COL4A6/COL4A5 | 32 |
| HP_ABNORMALITY_OF_THE_AUDITORY_CANAL | HP_ABNORMALITY_OF_THE_AUDITORY_CANAL | HP_ABNORMALITY_OF_THE_AUDITORY_CANAL | 14/1438 | 72/23056 | 0.1944444 | 3.117602 | 4.641432 | 0.0001244 | 0.0009728 | 0.0006254 | TBX15/TWIST2/COL7A1/FGFRL1/FAT4/EDN1/HOXA2/GLI3/FGFR2/GRIP1/FREM2/SIX1/MAF/SIX5 | 14 |
| DALESSIO_TSA_RESPONSE | DALESSIO_TSA_RESPONSE | DALESSIO_TSA_RESPONSE | 8/1438 | 26/23056 | 0.3076923 | 4.933348 | 5.175547 | 0.0001273 | 0.0009927 | 0.0006382 | CLU/ANXA1/FOS/GADD45B/LGALS1/SSX1/SPANXC/SPANXA1 | 8 |
| GOBP_INNERVATION | GOBP_INNERVATION | GOBP_INNERVATION | 8/1438 | 26/23056 | 0.3076923 | 4.933348 | 5.175547 | 0.0001273 | 0.0009927 | 0.0006382 | ECE1/VCAM1/ITGA4/SERPINE2/EDN1/SEMA3A/SULF1/NRP1 | 8 |
| GOBP_SECONDARY_PALATE_DEVELOPMENT | GOBP_SECONDARY_PALATE_DEVELOPMENT | GOBP_SECONDARY_PALATE_DEVELOPMENT | 8/1438 | 26/23056 | 0.3076923 | 4.933348 | 5.175547 | 0.0001273 | 0.0009927 | 0.0006382 | TGFB2/ITGB6/TGFBR2/WNT5A/LEF1/ITGB8/FZD1/LRRC32 | 8 |
| HP_ORTHOPNEA | HP_ORTHOPNEA | HP_ORTHOPNEA | 8/1438 | 26/23056 | 0.3076923 | 4.933348 | 5.175547 | 0.0001273 | 0.0009927 | 0.0006382 | AGRN/DOK7/CITED2/FLNC/MYPN/COL13A1/ACTC1/GATA6 | 8 |
| JI_METASTASIS_REPRESSED_BY_STK11 | JI_METASTASIS_REPRESSED_BY_STK11 | JI_METASTASIS_REPRESSED_BY_STK11 | 8/1438 | 26/23056 | 0.3076923 | 4.933348 | 5.175547 | 0.0001273 | 0.0009927 | 0.0006382 | LTBP1/ITGB5/F2RL1/ID4/LGSN/PON3/GDF15/SIM2 | 8 |
| WEINMANN_ADAPTATION_TO_HYPOXIA_UP | WEINMANN_ADAPTATION_TO_HYPOXIA_UP | WEINMANN_ADAPTATION_TO_HYPOXIA_UP | 8/1438 | 26/23056 | 0.3076923 | 4.933348 | 5.175547 | 0.0001273 | 0.0009927 | 0.0006382 | COL3A1/TPBG/MEST/NNMT/TPM1/NQO1/SLC16A3/HMOX1 | 8 |
| LEE_DIFFERENTIATING_T_LYMPHOCYTE | LEE_DIFFERENTIATING_T_LYMPHOCYTE | LEE_DIFFERENTIATING_T_LYMPHOCYTE | 27/1438 | 200/23056 | 0.1350000 | 2.164506 | 4.265903 | 0.0001280 | 0.0009972 | 0.0006411 | CD53/MR1/PTPRC/LAX1/RASSF5/SP110/CD96/LEF1/IL7R/DOCK2/PSMB9/TRIM56/GIMAP2/TMEM71/AQP3/APBB1IP/PGGHG/ARHGDIB/NCKAP1L/SELPLG/SLC46A3/LAT/SLFN5/GMFG/RAC2/ITM2A/ARHGEF6 | 27 |
| GAVIN_FOXP3_TARGETS_CLUSTER_P2 | GAVIN_FOXP3_TARGETS_CLUSTER_P2 | GAVIN_FOXP3_TARGETS_CLUSTER_P2 | 15/1438 | 81/23056 | 0.1851852 | 2.969144 | 4.578746 | 0.0001287 | 0.0010025 | 0.0006445 | IFI44L/FCGR2A/ITGA4/DAW1/SERPINB1/DSP/GJA1/LY6K/CASP4/NCKAP1L/CPM/LDHD/SLFN5/CCL5/CD22 | 15 |
| BENPORATH_NOS_TARGETS | BENPORATH_NOS_TARGETS | BENPORATH_NOS_TARGETS | 25/1438 | 179/23056 | 0.1396648 | 2.239299 | 4.292964 | 0.0001302 | 0.0010132 | 0.0006513 | DHRS3/OLFML3/IFI16/KDR/IRX2/SMIM3/B3GALT4/COL12A1/LAMA4/GJA1/CCN2/THBS2/SULF1/MSC/HAS2/DKK1/ANKRD1/HHEX/FGFR2/H2AJ/FOXO1/ZIC2/ZFP36L1/SALL1/JUP | 25 |
| GOBP_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION | 10/1438 | 40/23056 | 0.2500000 | 4.008345 | 4.911306 | 0.0001304 | 0.0010140 | 0.0006519 | TNFRSF1B/DLX1/DLX2/HES1/ID4/TNFRSF21/PTPRZ1/PTN/SHH/NOTCH1 | 10 |
| WP_INFLUENCE_OF_LAMINOPATHIES_ON_WNT_SIGNALING | WP_INFLUENCE_OF_LAMINOPATHIES_ON_WNT_SIGNALING | WP_INFLUENCE_OF_LAMINOPATHIES_ON_WNT_SIGNALING | 10/1438 | 40/23056 | 0.2500000 | 4.008345 | 4.911306 | 0.0001304 | 0.0010140 | 0.0006519 | PPARG/HES1/SPP1/LEF1/RUNX2/CEBPD/TCF7L2/WNT10B/HMGA2/CEBPB | 10 |
| GOBP_LEUKOCYTE_APOPTOTIC_PROCESS | GOBP_LEUKOCYTE_APOPTOTIC_PROCESS | GOBP_LEUKOCYTE_APOPTOTIC_PROCESS | 18/1438 | 109/23056 | 0.1651376 | 2.647714 | 4.447197 | 0.0001345 | 0.0010450 | 0.0006718 | ITPKB/WNT5A/BCL6/SLC7A11/IL7R/TNFRSF21/IL6/GLI3/IDO1/ST3GAL1/CD274/ANXA1/FAS/BMP4/CCL5/CCR7/AXL/BIRC7 | 18 |
| GOBP_REGULATION_OF_VASOCONSTRICTION | GOBP_REGULATION_OF_VASOCONSTRICTION | GOBP_REGULATION_OF_VASOCONSTRICTION | 13/1438 | 64/23056 | 0.2031250 | 3.256780 | 4.662782 | 0.0001354 | 0.0010516 | 0.0006760 | ECE1/EDN2/PTGS2/AGT/HRH1/EDN1/CAV1/ADM/ARHGAP42/KCNA5/MMP2/ADRA1D/CYSLTR1 | 13 |
| CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_UP | 7/1438 | 20/23056 | 0.3500000 | 5.611683 | 5.321391 | 0.0001364 | 0.0010552 | 0.0006784 | TGFB2/EDN1/ADM/AJUBA/THBS1/NECTIN2/PDGFB | 7 |
| GOBP_MIDDLE_EAR_MORPHOGENESIS | GOBP_MIDDLE_EAR_MORPHOGENESIS | GOBP_MIDDLE_EAR_MORPHOGENESIS | 7/1438 | 20/23056 | 0.3500000 | 5.611683 | 5.321391 | 0.0001364 | 0.0010552 | 0.0006784 | PRRX1/OSR1/NKX3-2/EDN1/HOXA2/SIX1/NOG | 7 |
| GOBP_REVERSE_CHOLESTEROL_TRANSPORT | GOBP_REVERSE_CHOLESTEROL_TRANSPORT | GOBP_REVERSE_CHOLESTEROL_TRANSPORT | 7/1438 | 20/23056 | 0.3500000 | 5.611683 | 5.321391 | 0.0001364 | 0.0010552 | 0.0006784 | CLU/APOC3/APOA1/CES1/CETP/LIPG/APOE | 7 |
| GOBP_WOUND_HEALING_SPREADING_OF_EPIDERMAL_CELLS | GOBP_WOUND_HEALING_SPREADING_OF_EPIDERMAL_CELLS | GOBP_WOUND_HEALING_SPREADING_OF_EPIDERMAL_CELLS | 7/1438 | 20/23056 | 0.3500000 | 5.611683 | 5.321391 | 0.0001364 | 0.0010552 | 0.0006784 | PHLDB2/ARHGAP24/HBEGF/RREB1/COL5A1/ITGA5/AJUBA | 7 |
| GOCC_APICOLATERAL_PLASMA_MEMBRANE | GOCC_APICOLATERAL_PLASMA_MEMBRANE | GOCC_APICOLATERAL_PLASMA_MEMBRANE | 7/1438 | 20/23056 | 0.3500000 | 5.611683 | 5.321391 | 0.0001364 | 0.0010552 | 0.0006784 | FZD6/EPPK1/CRB2/CLDN6/KRT19/JUP/THBD | 7 |
| GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH2_GROUP_OF_DONORS | 7/1438 | 20/23056 | 0.3500000 | 5.611683 | 5.321391 | 0.0001364 | 0.0010552 | 0.0006784 | VCAM1/DDO/LOXL2/RNLS/LOXL4/LOXL1/IL4I1 | 7 |
| DORN_ADENOVIRUS_INFECTION_12HR_DN | DORN_ADENOVIRUS_INFECTION_12HR_DN | DORN_ADENOVIRUS_INFECTION_12HR_DN | 9/1438 | 33/23056 | 0.2727273 | 4.372740 | 5.000496 | 0.0001369 | 0.0010567 | 0.0006793 | ELF3/KYNU/COL7A1/IER3/IL6/NFKBIA/ANPEP/TNFRSF12A/BACE2 | 9 |
| GOBP_FLUID_TRANSPORT | GOBP_FLUID_TRANSPORT | GOBP_FLUID_TRANSPORT | 9/1438 | 33/23056 | 0.2727273 | 4.372740 | 5.000496 | 0.0001369 | 0.0010567 | 0.0006793 | CSF2/EDN1/AQP1/EXT1/HAS2/AQP7/AQP3/EDNRB/SLC14A1 | 9 |
| GOBP_POSITIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS | 9/1438 | 33/23056 | 0.2727273 | 4.372740 | 5.000496 | 0.0001369 | 0.0010567 | 0.0006793 | LDLRAP1/AGT/IL1A/DAB2/BMP6/ADM/APOA1/CES1/APOE | 9 |
| GOBP_REGULATION_OF_NEUTROPHIL_CHEMOTAXIS | GOBP_REGULATION_OF_NEUTROPHIL_CHEMOTAXIS | GOBP_REGULATION_OF_NEUTROPHIL_CHEMOTAXIS | 9/1438 | 33/23056 | 0.2727273 | 4.372740 | 5.000496 | 0.0001369 | 0.0010567 | 0.0006793 | DPP4/SLIT2/CXCL8/EDN1/C3AR1/NCKAP1L/CCR7/C5AR1/RAC2 | 9 |
| HP_FRAGILE_NAILS | HP_FRAGILE_NAILS | HP_FRAGILE_NAILS | 9/1438 | 33/23056 | 0.2727273 | 4.372740 | 5.000496 | 0.0001369 | 0.0010567 | 0.0006793 | LAMC2/LAMB3/COL7A1/DSP/GJA1/TRPS1/PRKD1/DLX3/ITGB4 | 9 |
| HP_ABNORMAL_UPPER_LIMB_BONE_MORPHOLOGY | HP_ABNORMAL_UPPER_LIMB_BONE_MORPHOLOGY | HP_ABNORMAL_UPPER_LIMB_BONE_MORPHOLOGY | 50/1438 | 467/23056 | 0.1070664 | 1.716636 | 4.035179 | 0.0001393 | 0.0010746 | 0.0006908 | PTCH2/PTPN22/TBX15/PRG4/CYP26B1/COL3A1/COL5A2/TWIST2/WNT5A/CD96/FGFRL1/FGFR3/FAT4/SPARC/HFE/RUNX2/TENT5A/GLI3/TMEM270/SAMD9/SHH/RSPO2/TRPS1/EXT1/COLEC10/TPM2/COL27A1/COL5A1/NOTCH1/FGFR2/ALX4/MMP14/PRKD1/DACT1/FBN1/SMAD6/SALL1/MMP2/MAF/COL1A1/NOG/KCNJ2/PIEZO2/TGFB1/RRAS/BMP2/COL9A3/IL2RB/GPC4/BGN | 50 |
| HP_ABNORMAL_CARDIAC_TEST | HP_ABNORMAL_CARDIAC_TEST | HP_ABNORMAL_CARDIAC_TEST | 19/1438 | 119/23056 | 0.1596639 | 2.559951 | 4.400180 | 0.0001406 | 0.0010841 | 0.0006969 | TNNC1/TECRL/TRDN/LAMA2/CITED2/SEMA3A/KCNA5/SCNN1A/ACTC1/FBN1/HCN4/ALPK3/JUP/CAVIN1/KCNJ2/GATA6/CACNA1A/SCN1B/GPC4 | 19 |
| GOBP_ACUTE_PHASE_RESPONSE | GOBP_ACUTE_PHASE_RESPONSE | GOBP_ACUTE_PHASE_RESPONSE | 11/1438 | 48/23056 | 0.2291667 | 3.674316 | 4.783526 | 0.0001417 | 0.0010882 | 0.0006996 | PTGS2/IL1A/IL1B/FN1/IL6/MBL2/SAA1/EDNRB/SERPINA1/TNFRSF11A/CEBPB | 11 |
| GOBP_CELLULAR_RESPONSE_TO_AMYLOID_BETA | GOBP_CELLULAR_RESPONSE_TO_AMYLOID_BETA | GOBP_CELLULAR_RESPONSE_TO_AMYLOID_BETA | 11/1438 | 48/23056 | 0.2291667 | 3.674316 | 4.783526 | 0.0001417 | 0.0010882 | 0.0006996 | VCAM1/ITGA4/EPHA4/ADRB2/GJA1/CD36/CASP4/IGF1/ICAM1/CACNA1A/PRNP | 11 |
| GOBP_EXOCRINE_SYSTEM_DEVELOPMENT | GOBP_EXOCRINE_SYSTEM_DEVELOPMENT | GOBP_EXOCRINE_SYSTEM_DEVELOPMENT | 11/1438 | 48/23056 | 0.2291667 | 3.674316 | 4.783526 | 0.0001417 | 0.0010882 | 0.0006996 | TGFB2/FOXC1/PDGFA/SEMA3C/SEMA3A/SHH/NRP1/FGFR2/SOX9/TGFB1/TGM2 | 11 |
| GOBP_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | 11/1438 | 48/23056 | 0.2291667 | 3.674316 | 4.783526 | 0.0001417 | 0.0010882 | 0.0006996 | EPHA2/TGFB2/DPP4/SERPINE1/PODXL/ADAM9/PLAU/NCKAP1L/PIEZO1/CCL5/LIF | 11 |
| GOBP_REGULATION_OF_VASCULAR_PERMEABILITY | GOBP_REGULATION_OF_VASCULAR_PERMEABILITY | GOBP_REGULATION_OF_VASCULAR_PERMEABILITY | 11/1438 | 48/23056 | 0.2291667 | 3.674316 | 4.783526 | 0.0001417 | 0.0010882 | 0.0006996 | HRH1/SLIT2/BMP6/ANGPT1/TEK/ADM/PTPRJ/MYLK3/PLVAP/TGFB1/APOE | 11 |
| GOCC_INTERCALATED_DISC | GOCC_INTERCALATED_DISC | GOCC_INTERCALATED_DISC | 11/1438 | 48/23056 | 0.2291667 | 3.674316 | 4.783526 | 0.0001417 | 0.0010882 | 0.0006996 | VAMP5/DES/DSP/GJA1/VCL/KCNA5/MYH1/JUP/KCNJ2/DSG2/SCN1B | 11 |
| HALMOS_CEBPA_TARGETS_UP | HALMOS_CEBPA_TARGETS_UP | HALMOS_CEBPA_TARGETS_UP | 11/1438 | 48/23056 | 0.2291667 | 3.674316 | 4.783526 | 0.0001417 | 0.0010882 | 0.0006996 | PTGS2/IL1R1/EPHA4/CXCL8/CXCL3/CXCL2/SEMA3C/FAS/IL4R/BMP2/HMOX1 | 11 |
| GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | 12/1438 | 56/23056 | 0.2142857 | 3.435724 | 4.706656 | 0.0001422 | 0.0010914 | 0.0007016 | GBP2/PTPN22/LPP/LEF1/DNMBP/PGGHG/CCR7/ABCA6/KCNN4/COL9A3/APOBEC3G/CELSR1 | 12 |
| GOBP_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 31/1438 | 245/23056 | 0.1265306 | 2.028713 | 4.175029 | 0.0001428 | 0.0010951 | 0.0007040 | ZC3H12A/VCAM1/IFI16/PTPRC/NUAK2/MAP1LC3C/ITGA4/UCN2/IL15/PDK4/GSDMD/AQP3/AKR1C3/FAS/FOSL1/NUAK1/POSTN/FOXO1/DNAJC15/PRKD1/FOS/CD68/MYH13/MYOCD/COL1A1/WIPI1/AXL/CYP24A1/MN1/GAS2L1/HMOX1 | 31 |
| PEDRIOLI_MIR31_TARGETS_UP | PEDRIOLI_MIR31_TARGETS_UP | PEDRIOLI_MIR31_TARGETS_UP | 29/1438 | 223/23056 | 0.1300448 | 2.085058 | 4.199313 | 0.0001431 | 0.0010970 | 0.0007052 | TTLL10/AADACL4/PTCH2/OLFML3/ATP2B4/EVA1A/PLSCR2/P3H2/NWD2/PCDH10/IRX2/ZNF366/ADGRG6/HOXA2/PRR15/INHBA/ASPH/TNFRSF11B/ALX4/MMP1/TAGLN/MPZL2/KRT80/KRT7/RAB20/FBLN5/KRT17/FOXS1/KIAA1755 | 29 |
| HP_HEMOLYTIC_ANEMIA | HP_HEMOLYTIC_ANEMIA | HP_HEMOLYTIC_ANEMIA | 20/1438 | 129/23056 | 0.1550388 | 2.485795 | 4.364500 | 0.0001438 | 0.0011020 | 0.0007084 | TNFRSF4/PTPN22/FCGR2A/CFH/GYPC/CASP10/SPP1/CFI/RHAG/TNFAIP3/FAS/NFKB2/EPB42/LAT/PIEZO1/C3/KCNN4/THBD/HMOX1/IL2RB | 20 |
| HP_SEROSITIS | HP_SEROSITIS | HP_SEROSITIS | 14/1438 | 73/23056 | 0.1917808 | 3.074895 | 4.579398 | 0.0001451 | 0.0011113 | 0.0007144 | PTPN22/FCGR2A/PRG4/ARHGAP24/IL6/CRB2/FAS/WT1/TNFRSF1A/MYO1E/MAF/ELANE/APOL1/TBC1D8B | 14 |
| GOBP_NEGATIVE_REGULATION_OF_VIRAL_PROCESS | GOBP_NEGATIVE_REGULATION_OF_VIRAL_PROCESS | GOBP_NEGATIVE_REGULATION_OF_VIRAL_PROCESS | 16/1438 | 91/23056 | 0.1758242 | 2.819056 | 4.484229 | 0.0001471 | 0.0011259 | 0.0007238 | IFI16/RNASEL/PARP10/GSN/MBL2/IFITM2/IFITM3/TRIM5/HMGA2/OASL/CCL5/ZFP36/MX1/APOBEC3A/APOBEC3G/APOBEC3H | 16 |
| RADMACHER_AML_PROGNOSIS | RADMACHER_AML_PROGNOSIS | RADMACHER_AML_PROGNOSIS | 15/1438 | 82/23056 | 0.1829268 | 2.932935 | 4.522309 | 0.0001486 | 0.0011359 | 0.0007302 | AGRN/S1PR1/AGT/GYPC/TMEM158/SKAP2/ANGPT1/TSPAN32/FLT3/FOXO1/SLC7A7/HOXB2/COL1A1/ADGRE1/TGM2 | 15 |
| VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP | 15/1438 | 82/23056 | 0.1829268 | 2.932935 | 4.522309 | 0.0001486 | 0.0011359 | 0.0007302 | IER3/PODXL/PLEKHA2/HAS2/HKDC1/PHLDA2/ADM/CGNL1/ALPK3/CLDN6/KRT19/ITGA3/SLC16A3/DSG2/LGALS2 | 15 |
| GOBP_REGULATION_OF_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_MUSCLE_CONTRACTION | 24/1438 | 170/23056 | 0.1411765 | 2.263536 | 4.264630 | 0.0001487 | 0.0011360 | 0.0007303 | ZC3H12A/EDN2/CASQ1/PTGS2/BMP10/TNNC1/NPNT/ITGA2/ADRB2/DSP/EDN1/CCN2/CAV1/STC1/ARHGAP42/SPX/TPM1/HCN4/MYOCD/JUP/KCNJ2/DSG2/CNN1/MYL9 | 24 |
| MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | 32/1438 | 257/23056 | 0.1245136 | 1.996374 | 4.142718 | 0.0001520 | 0.0011605 | 0.0007461 | ATP2B4/LONRF2/HNMT/FGFRL1/DOK7/NPNT/RBM24/TPBG/TPD52L1/BMPER/FZD1/STC1/ZNF703/MYBL1/PTGR1/COL5A1/MYOF/CD44/SYT12/PRSS23/PGR/ADAMTS15/AMIGO2/METTL7B/FREM2/CA12/MT2A/RHBDF2/IL27RA/TFAP2C/PNPLA3/COL4A5 | 32 |
| GOBP_INOSITOL_LIPID_MEDIATED_SIGNALING | GOBP_INOSITOL_LIPID_MEDIATED_SIGNALING | GOBP_INOSITOL_LIPID_MEDIATED_SIGNALING | 25/1438 | 181/23056 | 0.1381215 | 2.214555 | 4.230875 | 0.0001556 | 0.0011875 | 0.0007634 | TGFB2/AGT/FN1/SERPINE2/PLD1/KDR/EGF/PDGFC/NPR3/F2RL1/EDN1/PDGFA/ANGPT1/TEK/IGF1/FLT3/FLT1/ZFP36L1/LTK/TNFAIP8L3/ADAP2/CCL5/CSF3/SOX9/PDGFB | 25 |
| MULLIGHAN_MLL_SIGNATURE_2_DN | MULLIGHAN_MLL_SIGNATURE_2_DN | MULLIGHAN_MLL_SIGNATURE_2_DN | 34/1438 | 280/23056 | 0.1214286 | 1.946910 | 4.111530 | 0.0001568 | 0.0011956 | 0.0007686 | AGRN/TNFRSF4/DHRS3/EDN2/TIE1/IFI16/LAX1/CD34/PTPN14/TFPI/SERPINE2/TGFBR2/LAMB2/CD96/TM4SF1/STK32B/ARAP2/CXCL8/CXCL2/NPR3/C9/DAB2/SPARC/TNFRSF21/RBPMS/MYRF/LOXL1/MMP2/CETP/CAVIN1/RUNX1/ICOSLG/MN1/ITM2A | 34 |
| HP_ABNORMALITY_OF_THE_AMNIOTIC_FLUID | HP_ABNORMALITY_OF_THE_AMNIOTIC_FLUID | HP_ABNORMALITY_OF_THE_AMNIOTIC_FLUID | 43/1438 | 385/23056 | 0.1116883 | 1.790741 | 4.035372 | 0.0001585 | 0.0012083 | 0.0007768 | AGRN/HSPG2/PRRX1/LMOD1/AGT/ACTG2/ITGA6/CD96/MYLK/FGFR3/DOK7/ADAMTS3/RREB1/DSP/RHAG/ADGRG6/BMPER/GLI3/FGF20/PLAG1/RSPO2/TPM2/CRB2/ITGA8/MYPN/COL13A1/ALX4/EFEMP2/ITGA7/HMGA2/FBLN5/FBN1/GLDN/FOXF1/PIEZO1/LHX1/JUP/SOX9/ITGB4/GATA6/PLVAP/MYL9/GPC4 | 43 |
| WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP | WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP | WUNDER_INFLAMMATORY_RESPONSE_AND_CHOLESTEROL_UP | 13/1438 | 65/23056 | 0.2000000 | 3.206676 | 4.594842 | 0.0001597 | 0.0012169 | 0.0007823 | GBP2/CTSS/SP110/UBA7/CXCL6/PLAC8/HLA-E/PSMB8/PSMB9/CASP1/SERPINA1/PSMB10/CCL5 | 13 |
| REACTOME_CELL_CELL_COMMUNICATION | REACTOME_CELL_CELL_COMMUNICATION | REACTOME_CELL_CELL_COMMUNICATION | 20/1438 | 130/23056 | 0.1538462 | 2.466674 | 4.325092 | 0.0001602 | 0.0012198 | 0.0007842 | FBLIM1/LAMC2/LAMB3/ITGA6/CLDN1/CLDN16/CDH9/SKAP2/FLNC/SFTPD/CLDN6/CDH13/CDH15/CLDN7/JUP/ITGB4/NECTIN2/SIRPG/SIRPA/ARHGEF6 | 20 |
| GOBP_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | GOBP_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | GOBP_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | 17/1438 | 101/23056 | 0.1683168 | 2.698688 | 4.412552 | 0.0001610 | 0.0012254 | 0.0007878 | TNFRSF1B/EPHA2/IFI16/IKBKE/ACKR3/SHISA5/SOD2/CLU/NACC2/CD44/TNFRSF1A/NFATC4/CRIP1/BCL2A1/NUPR1/BCL3/HMOX1 | 17 |
| AMIT_EGF_RESPONSE_120_MCF10A | AMIT_EGF_RESPONSE_120_MCF10A | AMIT_EGF_RESPONSE_120_MCF10A | 10/1438 | 41/23056 | 0.2439024 | 3.910580 | 4.810833 | 0.0001630 | 0.0012374 | 0.0007955 | EPHA2/IL1A/IL1B/EREG/HBEGF/FOSL1/ALDH1A3/SERPINB2/GDF15/LIF | 10 |
| EPPERT_CE_HSC_LSC | EPPERT_CE_HSC_LSC | EPPERT_CE_HSC_LSC | 10/1438 | 41/23056 | 0.2439024 | 3.910580 | 4.810833 | 0.0001630 | 0.0012374 | 0.0007955 | TFPI/PLSCR4/INPP4B/CRHBP/ADGRG6/RBPMS/DRAM1/FLT3/HOXB2/HOXB3 | 10 |
| GOBP_POSITIVE_REGULATION_OF_HEART_GROWTH | GOBP_POSITIVE_REGULATION_OF_HEART_GROWTH | GOBP_POSITIVE_REGULATION_OF_HEART_GROWTH | 10/1438 | 41/23056 | 0.2439024 | 3.910580 | 4.810833 | 0.0001630 | 0.0012374 | 0.0007955 | BMP10/EDN1/ZFPM2/NOTCH1/FGFR2/WT1/YAP1/GLI1/IGF1/GATA6 | 10 |
| HP_ABNORMAL_TRICUSPID_VALVE_MORPHOLOGY | HP_ABNORMAL_TRICUSPID_VALVE_MORPHOLOGY | HP_ABNORMAL_TRICUSPID_VALVE_MORPHOLOGY | 10/1438 | 41/23056 | 0.2439024 | 3.910580 | 4.810833 | 0.0001630 | 0.0012374 | 0.0007955 | COL5A2/PLD1/RREB1/COL5A1/MYRF/FBN1/FOXF1/COL1A1/GATA6/JPH2 | 10 |
| REACTOME_CELL_JUNCTION_ORGANIZATION | REACTOME_CELL_JUNCTION_ORGANIZATION | REACTOME_CELL_JUNCTION_ORGANIZATION | 16/1438 | 92/23056 | 0.1739130 | 2.788414 | 4.432946 | 0.0001679 | 0.0012745 | 0.0008193 | FBLIM1/LAMC2/LAMB3/ITGA6/CLDN1/CLDN16/CDH9/FLNC/CLDN6/CDH13/CDH15/CLDN7/JUP/ITGB4/NECTIN2/ARHGEF6 | 16 |
| ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN | ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN | ADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN | 14/1438 | 74/23056 | 0.1891892 | 3.033342 | 4.518421 | 0.0001689 | 0.0012801 | 0.0008229 | FCGR2A/PTPN7/ITGB5/CXCL8/CXCL2/GYPA/IER3/ANGPT1/SLC2A14/MT2A/NQO1/OSGIN1/CAVIN1/CEBPB | 14 |
| GOBP_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | GOBP_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | GOBP_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | 14/1438 | 74/23056 | 0.1891892 | 3.033342 | 4.518421 | 0.0001689 | 0.0012801 | 0.0008229 | ZC3H12A/PTPN22/IL1B/IL15/STING1/TRIM38/MICB/TNFAIP3/DDX58/HTRA1/TSPAN32/DHX58/IL12RB1/APOBEC3G | 14 |
| GOBP_CELL_MATURATION | GOBP_CELL_MATURATION | GOBP_CELL_MATURATION | 25/1438 | 182/23056 | 0.1373626 | 2.202387 | 4.200135 | 0.0001699 | 0.0012868 | 0.0008272 | AGRN/PPARG/HES1/KDR/EREG/IL15/EDN1/TCP11/RUNX2/TDRD6/GJA1/FAM20C/PAEP/PGR/RND1/EDNRB/EPB42/GLDN/BNC1/SOX8/HOXB13/C3/KLF2/AXL/BFSP1 | 25 |
| DELASERNA_MYOD_TARGETS_DN | DELASERNA_MYOD_TARGETS_DN | DELASERNA_MYOD_TARGETS_DN | 12/1438 | 57/23056 | 0.2105263 | 3.375448 | 4.631085 | 0.0001700 | 0.0012868 | 0.0008272 | GBP2/CD34/SLIT2/TGFBI/FZD1/RBPMS/S1PR3/MS4A4A/POSTN/MMP2/EMILIN2/THBD | 12 |
| GOBP_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION | GOBP_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION | GOBP_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION | 12/1438 | 57/23056 | 0.2105263 | 3.375448 | 4.631085 | 0.0001700 | 0.0012868 | 0.0008272 | IFI16/RNASEL/PARP10/IFITM2/IFITM3/HMGA2/OASL/CCL5/MX1/APOBEC3A/APOBEC3G/APOBEC3H | 12 |
| GOBP_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_ALPHA_BETA_T_CELL_DIFFERENTIATION | 18/1438 | 111/23056 | 0.1621622 | 2.600007 | 4.358065 | 0.0001705 | 0.0012878 | 0.0008279 | RUNX3/ZC3H12A/ITPKB/NLRP3/TGFBR2/BCL6/LEF1/IL6/GLI3/SHH/ANXA1/NCKAP1L/STAT6/IL4R/IL12RB1/BCL3/RELB/RUNX1 | 18 |
| GOBP_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | GOBP_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | GOBP_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 18/1438 | 111/23056 | 0.1621622 | 2.600007 | 4.358065 | 0.0001705 | 0.0012878 | 0.0008279 | TGFB2/AGT/FN1/SERPINE2/KDR/EGF/PDGFC/F2RL1/PDGFA/ANGPT1/TEK/IGF1/FLT3/FLT1/CCL5/CSF3/SOX9/PDGFB | 18 |
| HP_HYPERLIPIDEMIA | HP_HYPERLIPIDEMIA | HP_HYPERLIPIDEMIA | 18/1438 | 111/23056 | 0.1621622 | 2.600007 | 4.358065 | 0.0001705 | 0.0012878 | 0.0008279 | LDLRAP1/CFH/PPARG/PSMB8/PSMB9/STX11/CAV1/APOC3/SLC7A7/PYGL/FOS/CYP19A1/CETP/PSMB10/CAVIN1/CREB3L3/PLVAP/APOE | 18 |
| GOBP_FOCAL_ADHESION_ASSEMBLY | GOBP_FOCAL_ADHESION_ASSEMBLY | GOBP_FOCAL_ADHESION_ASSEMBLY | 15/1438 | 83/23056 | 0.1807229 | 2.897599 | 4.466721 | 0.0001711 | 0.0012878 | 0.0008279 | S100A10/EPHA3/PHLDB2/KDR/ITGA2/PTPRK/TRIP6/TEK/NRP1/VCL/PTPRJ/MMP14/AJUBA/THBS1/SDC4 | 15 |
| GOBP_AXIS_ELONGATION | GOBP_AXIS_ELONGATION | GOBP_AXIS_ELONGATION | 8/1438 | 27/23056 | 0.2962963 | 4.750631 | 5.029247 | 0.0001711 | 0.0012878 | 0.0008279 | WNT5A/SHH/FGFR2/YAP1/BMP4/SIX1/SIX4/SOX9 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_AXON_EXTENSION_INVOLVED_IN_AXON_GUIDANCE | GOBP_NEGATIVE_REGULATION_OF_AXON_EXTENSION_INVOLVED_IN_AXON_GUIDANCE | GOBP_NEGATIVE_REGULATION_OF_AXON_EXTENSION_INVOLVED_IN_AXON_GUIDANCE | 8/1438 | 27/23056 | 0.2962963 | 4.750631 | 5.029247 | 0.0001711 | 0.0012878 | 0.0008279 | SEMA3B/WNT5A/SEMA5A/SEMA3C/SEMA3A/SEMA3D/NRP1/SEMA6B | 8 |
| GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 8/1438 | 27/23056 | 0.2962963 | 4.750631 | 5.029247 | 0.0001711 | 0.0012878 | 0.0008279 | TGFB2/CD96/BCL6/HFE/ANGPT1/APOA1/TGFB1/HMOX1 | 8 |
| GOBP_POSITIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION | 8/1438 | 27/23056 | 0.2962963 | 4.750631 | 5.029247 | 0.0001711 | 0.0012878 | 0.0008279 | AGT/PHLDB2/IL6/EFEMP2/SOX9/TGFB1/BMP2/RUNX1 | 8 |
| GOCC_HIGH_DENSITY_LIPOPROTEIN_PARTICLE | GOCC_HIGH_DENSITY_LIPOPROTEIN_PARTICLE | GOCC_HIGH_DENSITY_LIPOPROTEIN_PARTICLE | 8/1438 | 27/23056 | 0.2962963 | 4.750631 | 5.029247 | 0.0001711 | 0.0012878 | 0.0008279 | PLA2G7/CLU/SAA1/APOC3/APOA1/CETP/APOE/APOL1 | 8 |
| HP_ABNORMAL_SERUM_INTERLEUKIN_LEVEL | HP_ABNORMAL_SERUM_INTERLEUKIN_LEVEL | HP_ABNORMAL_SERUM_INTERLEUKIN_LEVEL | 8/1438 | 27/23056 | 0.2962963 | 4.750631 | 5.029247 | 0.0001711 | 0.0012878 | 0.0008279 | PTPN22/CASP10/SP110/PSMB8/STX11/FAS/IL12RB1/IL2RB | 8 |
| GOBP_BROWN_FAT_CELL_DIFFERENTIATION | GOBP_BROWN_FAT_CELL_DIFFERENTIATION | GOBP_BROWN_FAT_CELL_DIFFERENTIATION | 11/1438 | 49/23056 | 0.2244898 | 3.599330 | 4.697683 | 0.0001726 | 0.0012973 | 0.0008340 | PTGS2/LAMB3/PLAC8/ADRB2/RREB1/EBF2/FABP4/SIX1/DIO2/METRNL/CEBPB | 11 |
| GOBP_DENDRITIC_CELL_DIFFERENTIATION | GOBP_DENDRITIC_CELL_DIFFERENTIATION | GOBP_DENDRITIC_CELL_DIFFERENTIATION | 11/1438 | 49/23056 | 0.2244898 | 3.599330 | 4.697683 | 0.0001726 | 0.0012973 | 0.0008340 | ITGB6/TGFBR2/F2RL1/CSF2/ITGB8/FLT3/CCR7/AXL/RELB/CEBPB/LGALS1 | 11 |
| HP_ABNORMAL_TRACHEOBRONCHIAL_MORPHOLOGY | HP_ABNORMAL_TRACHEOBRONCHIAL_MORPHOLOGY | HP_ABNORMAL_TRACHEOBRONCHIAL_MORPHOLOGY | 37/1438 | 316/23056 | 0.1170886 | 1.877326 | 4.050080 | 0.0001739 | 0.0013064 | 0.0008398 | FCGR2A/PRRX1/CFAP221/CASP8/SLC34A2/FAT4/DNAH5/MCIDAS/CCNO/DSP/TAPBP/BMPER/TMEM270/SLC26A4/FGF20/RSPO2/ITGA8/MAP3K8/NFKB2/FGFR2/SLC22A18/MYRF/SCNN1A/NCKAP1L/GRIP1/FREM2/IRF9/IL21R/LAT/FOXF1/SOX9/TGFB1/RIN2/RAC2/ARSL/COL4A6/COL4A5 | 37 |
| HP_NEOPLASM_OF_THE_GASTROINTESTINAL_TRACT | HP_NEOPLASM_OF_THE_GASTROINTESTINAL_TRACT | HP_NEOPLASM_OF_THE_GASTROINTESTINAL_TRACT | 35/1438 | 293/23056 | 0.1194539 | 1.915250 | 4.066428 | 0.0001745 | 0.0013108 | 0.0008427 | ECE1/PTCH2/IL1B/CASP10/CASP8/TGFBR2/MITF/FGFR3/GDNF/HFE/SEMA3C/SEMA3D/MET/MSR1/PDGFRL/CTHRC1/COL14A1/PTPN3/TNFSF15/FAS/NFKB2/FGFR2/WT1/PTPRJ/STAT6/EDNRB/PYGL/SERPINA1/RHBDF2/PIEZO2/IL12RB1/BMP2/COL4A6/COL4A5/GPC4 | 35 |
| DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN | 9/1438 | 34/23056 | 0.2647059 | 4.244130 | 4.882255 | 0.0001760 | 0.0013195 | 0.0008483 | PTN/PDGFRL/RBPMS/HAS2/BMP4/SERPINB2/CNN1/DOK5/HMOX1 | 9 |
| HP_MALNUTRITION | HP_MALNUTRITION | HP_MALNUTRITION | 9/1438 | 34/23056 | 0.2647059 | 4.244130 | 4.882255 | 0.0001760 | 0.0013195 | 0.0008483 | LAMC2/LAMB3/ACTG2/COL7A1/SAA1/MMP1/SLC7A7/BMP4/DLX4 | 9 |
| GOBP_ICOSANOID_METABOLIC_PROCESS | GOBP_ICOSANOID_METABOLIC_PROCESS | GOBP_ICOSANOID_METABOLIC_PROCESS | 19/1438 | 121/23056 | 0.1570248 | 2.517638 | 4.316838 | 0.0001761 | 0.0013195 | 0.0008483 | EDN2/PTGS2/PLA2G4A/IL1B/MGLL/EDN1/ANXA1/PTGR1/PTGS1/AKR1C3/ALOX5/TNFRSF1A/ALOX5AP/CYP4F11/PLA2G4C/PTGIS/GGTLC3/GGTLC2/GGT1 | 19 |
| GOBP_REGULATION_OF_DNA_BINDING | GOBP_REGULATION_OF_DNA_BINDING | GOBP_REGULATION_OF_DNA_BINDING | 19/1438 | 121/23056 | 0.1570248 | 2.517638 | 4.316838 | 0.0001761 | 0.0013195 | 0.0008483 | RNF220/IFI16/SP100/PPARG/HES1/LEF1/EGF/ITGA2/FOXC1/MDFI/KLF4/HMGA2/IGF1/NFKBIA/MYOCD/TGFB1/BCL3/LIF/HMOX1 | 19 |
| YAGI_AML_WITH_INV_16_TRANSLOCATION | YAGI_AML_WITH_INV_16_TRANSLOCATION | YAGI_AML_WITH_INV_16_TRANSLOCATION | 45/1438 | 411/23056 | 0.1094891 | 1.755480 | 3.985765 | 0.0001780 | 0.0013304 | 0.0008553 | DHRS3/GBP2/S100A10/S100A2/ELF3/CRIM1/COL5A2/CPS1/SPP1/OSMR/SPARC/PXDC1/CAP2/NT5E/EPHB4/MEST/ADAM28/RBPMS/AQP7/SFTPD/HTR7/TLL2/PTPRE/WT1/PTPRJ/MMP1/OPCML/KCNA5/EMP1/KRT4/FLT1/FOXO1/SMAD6/ANPEP/RHBDF1/RRAD/KRT13/HAP1/BCAM/PRNP/SDC4/RUNX1/MN1/ITM2A/PLS3 | 45 |
| BIOCARTA_GRANULOCYTES_PATHWAY | BIOCARTA_GRANULOCYTES_PATHWAY | BIOCARTA_GRANULOCYTES_PATHWAY | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | IL1A/CXCL8/SELPLG/CSF3/PECAM1/ICAM1 | 6 |
| BIOCARTA_STEM_PATHWAY | BIOCARTA_STEM_PATHWAY | BIOCARTA_STEM_PATHWAY | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | CSF1/CXCL8/CSF2/IL6/CSF3/IL11 | 6 |
| GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_BUD | GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_BUD | GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_BUD | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | WNT5A/SHH/SULF1/FGFR2/BMP4/NOG | 6 |
| GOBP_ONE_CARBON_COMPOUND_TRANSPORT | GOBP_ONE_CARBON_COMPOUND_TRANSPORT | GOBP_ONE_CARBON_COMPOUND_TRANSPORT | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | RHAG/AQP1/AQP7/AQP3/SLC14A2/SLC14A1 | 6 |
| GOBP_REGULATION_OF_PLASMINOGEN_ACTIVATION | GOBP_REGULATION_OF_PLASMINOGEN_ACTIVATION | GOBP_REGULATION_OF_PLASMINOGEN_ACTIVATION | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | S100A10/SERPINE2/SERPINE1/THBS1/ANXA2/RUNX1 | 6 |
| GOBP_REGULATION_OF_PODOSOME_ASSEMBLY | GOBP_REGULATION_OF_PODOSOME_ASSEMBLY | GOBP_REGULATION_OF_PODOSOME_ASSEMBLY | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | CAPG/CSF2/ARHGEF5/GSN/LCP1/MSN | 6 |
| GOBP_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION | GOBP_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | COL3A1/LUM/THBS1/GATA6/SERPINB7/PSG9 | 6 |
| GOCC_MUSCLE_MYOSIN_COMPLEX | GOCC_MUSCLE_MYOSIN_COMPLEX | GOCC_MUSCLE_MYOSIN_COMPLEX | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | MYH13/MYH8/MYH4/MYH1/MYH2/MYL9 | 6 |
| HP_ABNORMAL_ERYTHROCYTE_PHYSIOLOGY | HP_ABNORMAL_ERYTHROCYTE_PHYSIOLOGY | HP_ABNORMAL_ERYTHROCYTE_PHYSIOLOGY | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | GYPC/SLC4A4/RHAG/EPB42/PIEZO1/KCNN4 | 6 |
| HP_URETHRAL_STRICTURE | HP_URETHRAL_STRICTURE | HP_URETHRAL_STRICTURE | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | LAMC2/LAMB3/ITGA6/COL7A1/MMP1/ITGB4 | 6 |
| XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | XU_RESPONSE_TO_TRETINOIN_AND_NSC682994_UP | 6/1438 | 15/23056 | 0.4000000 | 6.413352 | 5.408981 | 0.0001787 | 0.0013304 | 0.0008553 | CD53/NMI/ITGA6/CXCL8/ANXA1/MYH9 | 6 |
| GOBP_POSITIVE_REGULATION_OF_GONAD_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_GONAD_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_GONAD_DEVELOPMENT | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | CITED2/SEMA3A/ZFPM2/WT1/SOX9 | 5 |
| GOBP_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | FOXD1/BMP4/SOX8/NOG/SOX9 | 5 |
| GOBP_REGULATION_OF_MALE_GONAD_DEVELOPMENT | GOBP_REGULATION_OF_MALE_GONAD_DEVELOPMENT | GOBP_REGULATION_OF_MALE_GONAD_DEVELOPMENT | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | CITED2/SEMA3A/ZFPM2/WT1/SOX9 | 5 |
| GOBP_TRACHEA_MORPHOGENESIS | GOBP_TRACHEA_MORPHOGENESIS | GOBP_TRACHEA_MORPHOGENESIS | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | TGFBR2/SHH/RSPO2/BMP4/WNT7B | 5 |
| GOCC_FASCIA_ADHERENS | GOCC_FASCIA_ADHERENS | GOCC_FASCIA_ADHERENS | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | DES/DSP/GJA1/VCL/JUP | 5 |
| HP_PREMATURE_RUPTURE_OF_MEMBRANES | HP_PREMATURE_RUPTURE_OF_MEMBRANES | HP_PREMATURE_RUPTURE_OF_MEMBRANES | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | COL5A2/ADAMTS2/COL5A1/SERPINH1/COL1A1 | 5 |
| IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS | IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS | IYENGAR_RESPONSE_TO_ADIPOCYTE_FACTORS | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | ITGA2/TNFAIP3/STC1/MMP1/SOX9 | 5 |
| PID_VEGF_VEGFR_PATHWAY | PID_VEGF_VEGFR_PATHWAY | PID_VEGF_VEGFR_PATHWAY | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | NRP2/KDR/VEGFC/NRP1/FLT1 | 5 |
| REACTOME_HDL_REMODELING | REACTOME_HDL_REMODELING | REACTOME_HDL_REMODELING | 5/1438 | 10/23056 | 0.5000000 | 8.016690 | 5.723857 | 0.0001813 | 0.0013428 | 0.0008633 | APOC3/APOA1/CETP/LIPG/APOE | 5 |
| GOBP_NEURON_DEATH | GOBP_NEURON_DEATH | GOBP_NEURON_DEATH | 40/1438 | 352/23056 | 0.1136364 | 1.821975 | 4.008049 | 0.0001840 | 0.0013627 | 0.0008760 | TNFRSF1B/CSF1/CD34/TGFB2/DLX1/CASP8/THRB/WNT5A/GRID2/SLC7A11/GDNF/TFAP2A/TNFRSF21/SOD2/GPNMB/FZD1/PTPRZ1/FGF20/CLU/ANGPT1/NRP1/DKK1/FAS/PITX3/NFATC4/SIX1/SIX4/FOS/FOXB1/NUPR1/NQO1/CCL5/CSF3/IL27RA/MAG/AXL/APOE/PRNP/CEBPB/HMOX1 | 40 |
| FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP | FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP | FONTAINE_PAPILLARY_THYROID_CARCINOMA_UP | 13/1438 | 66/23056 | 0.1969697 | 3.158090 | 4.528207 | 0.0001877 | 0.0013883 | 0.0008925 | HSPB7/ECM1/S100A10/DPP4/CLDN1/SPP1/KLF4/NOTCH1/VCL/SLC22A18/KRT18/ABCC3/TENM1 | 13 |
| HP_SKIN_PIT | HP_SKIN_PIT | HP_SKIN_PIT | 13/1438 | 66/23056 | 0.1969697 | 3.158090 | 4.528207 | 0.0001877 | 0.0013883 | 0.0008925 | PTCH2/MITF/FGFRL1/TFAP2A/EDN1/CITED2/ZFPM2/SIX1/SALL1/KCNJ2/GATA6/GATA5/GPC4 | 13 |
| DE_YY1_TARGETS_DN | DE_YY1_TARGETS_DN | DE_YY1_TARGETS_DN | 16/1438 | 93/23056 | 0.1720430 | 2.758431 | 4.382347 | 0.0001913 | 0.0014140 | 0.0009090 | TGFB2/ITGA4/FN1/EPHA3/EGF/OSMR/PTP4A1/INHBA/MET/ANGPT1/TNFRSF11B/ANXA1/NRP1/FAS/BTG4/EPS8 | 16 |
| HP_ABNORMAL_SPUTUM | HP_ABNORMAL_SPUTUM | HP_ABNORMAL_SPUTUM | 18/1438 | 112/23056 | 0.1607143 | 2.576793 | 4.314231 | 0.0001915 | 0.0014146 | 0.0009094 | PTPN22/FCGR2A/TGFB2/CFAP221/COL3A1/COL5A2/IL17RC/TGFBR2/MYLK/SLC34A2/DNAH5/MCIDAS/CCNO/COL5A1/FAS/SCNN1A/FBN1/TGFB1 | 18 |
| GOBP_TELENCEPHALON_DEVELOPMENT | GOBP_TELENCEPHALON_DEVELOPMENT | GOBP_TELENCEPHALON_DEVELOPMENT | 31/1438 | 249/23056 | 0.1244980 | 1.996124 | 4.075990 | 0.0001917 | 0.0014146 | 0.0009094 | ATP2B4/SRD5A2/DLX1/DLX2/CCDC141/COL3A1/RARB/WNT5A/HES1/SLIT2/ANXA3/LEF1/FAT4/SLC7A11/DNAH5/ID4/MDGA1/AQP1/INHBA/GLI3/SEMA3A/FOXP2/SHH/EXT1/BMP4/FOXB1/ALDH1A3/SALL1/LHX1/SEMA6B/BMP2 | 31 |
| WP_MAPK_SIGNALING_PATHWAY | WP_MAPK_SIGNALING_PATHWAY | WP_MAPK_SIGNALING_PATHWAY | 31/1438 | 249/23056 | 0.1244980 | 1.996124 | 4.075990 | 0.0001917 | 0.0014146 | 0.0009094 | PLA2G4A/PTPN7/TGFB2/RASGRP3/IL1R1/IL1A/IL1B/TGFBR2/FGFR3/FGF5/EGF/FGF18/PDGFA/FLNC/FGF20/MAP3K8/FAS/NFKB2/FGFR2/CACNA2D4/TNFRSF1A/FOS/PLA2G4D/CACNA1A/TGFB1/RELB/PLA2G4C/RRAS/CACNG6/RAC2/PDGFB | 31 |
| GOBP_HOMEOSTASIS_OF_NUMBER_OF_CELLS | GOBP_HOMEOSTASIS_OF_NUMBER_OF_CELLS | GOBP_HOMEOSTASIS_OF_NUMBER_OF_CELLS | 34/1438 | 283/23056 | 0.1201413 | 1.926272 | 4.043671 | 0.0001923 | 0.0014185 | 0.0009119 | CSF1/ILDR2/ITPKB/FSTL1/BCL6/CXCL6/SLC7A11/IL7R/ADGRF5/RHAG/TNFAIP3/CITED2/IL6/INHBA/ARHGEF5/EXT1/ANXA1/NOTCH1/FAS/NCKAP1L/FLT3/TNFSF13B/BMP4/ZFP36L1/EPB42/LAT/CCR7/SOX9/TNFSF14/KLF2/ZFP36/AXL/HMOX1/LGALS2 | 34 |
| AMIT_EGF_RESPONSE_240_MCF10A | AMIT_EGF_RESPONSE_240_MCF10A | AMIT_EGF_RESPONSE_240_MCF10A | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | TGFA/SLC7A11/PLAU/MICAL2/EHD4/TNFRSF12A/BMP2 | 7 |
| DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS | DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS | DEBOSSCHER_NFKB_TARGETS_REPRESSED_BY_GLUCOCORTICOIDS | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | VCAM1/CXCL8/CSF2/EDN1/IL6/CCL5/IL11 | 7 |
| GESERICK_TERT_TARGETS_DN | GESERICK_TERT_TARGETS_DN | GESERICK_TERT_TARGETS_DN | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | ERRFI1/BHLHE40/HBEGF/IER3/KLF4/GADD45B/ZFP36 | 7 |
| GOBP_CELL_PROLIFERATION_INVOLVED_IN_HEART_MORPHOGENESIS | GOBP_CELL_PROLIFERATION_INVOLVED_IN_HEART_MORPHOGENESIS | GOBP_CELL_PROLIFERATION_INVOLVED_IN_HEART_MORPHOGENESIS | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | BMP10/TGFBR2/HES1/NOTCH1/BMP4/SIX1/SOX9 | 7 |
| GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_POSITIVE_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | TGFB2/PODXL/ADAM9/NCKAP1L/PIEZO1/CCL5/LIF | 7 |
| GOBP_PULMONARY_VALVE_DEVELOPMENT | GOBP_PULMONARY_VALVE_DEVELOPMENT | GOBP_PULMONARY_VALVE_DEVELOPMENT | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | TNFRSF1B/TGFB2/SLIT2/NOTCH1/TNFRSF1A/BMP4/SMAD6 | 7 |
| PLASARI_NFIC_TARGETS_BASAL_DN | PLASARI_NFIC_TARGETS_BASAL_DN | PLASARI_NFIC_TARGETS_BASAL_DN | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | IFI16/EPHA3/SLIT2/AHR/VWA5A/IGFBP6/MEOX1 | 7 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | CSF1/TFPI/TM4SF1/CRHBP/EPS8/ALDH1A2/GDF15 | 7 |
| VERRECCHIA_RESPONSE_TO_TGFB1_C5 | VERRECCHIA_RESPONSE_TO_TGFB1_C5 | VERRECCHIA_RESPONSE_TO_TGFB1_C5 | 7/1438 | 21/23056 | 0.3333333 | 5.344460 | 5.136953 | 0.0001936 | 0.0014210 | 0.0009135 | EPHA2/ITGA4/DDR1/ITGB8/TNFRSF1A/ITGA5/MMP2 | 7 |
| MOHANKUMAR_HOXA1_TARGETS_DN | MOHANKUMAR_HOXA1_TARGETS_DN | MOHANKUMAR_HOXA1_TARGETS_DN | 24/1438 | 173/23056 | 0.1387283 | 2.224284 | 4.168722 | 0.0001951 | 0.0014312 | 0.0009201 | TNFRSF9/PTCH2/LAMC2/LAMB3/LRP1B/NMI/EPHA4/PHLDB2/MGLL/SLCO2A1/PLD1/BTC/GASK1B/SEMA5A/INHBA/ANXA1/CLIC3/ARHGAP42/MMP3/CYP19A1/CGNL1/IL4R/MAF/GDF15 | 24 |
| GOBP_DEVELOPMENTAL_CELL_GROWTH | GOBP_DEVELOPMENTAL_CELL_GROWTH | GOBP_DEVELOPMENTAL_CELL_GROWTH | 29/1438 | 227/23056 | 0.1277533 | 2.048317 | 4.093704 | 0.0001952 | 0.0014312 | 0.0009201 | EDN2/CRABP2/AGT/ITGA4/NRP2/FN1/TGFBR2/LAMB2/SEMA3B/WNT5A/FOXL2/OSTN/SLIT2/SPP1/SEMA5A/EDN1/DDR1/SEMA3C/SEMA3A/SEMA3D/EXT1/NRP1/VCL/IGF1/TRPV2/SOX9/SEMA6B/MAG/APOE | 29 |
| GOMF_CALCIUM_DEPENDENT_PROTEIN_BINDING | GOMF_CALCIUM_DEPENDENT_PROTEIN_BINDING | GOMF_CALCIUM_DEPENDENT_PROTEIN_BINDING | 15/1438 | 84/23056 | 0.1785714 | 2.863103 | 4.411959 | 0.0001964 | 0.0014385 | 0.0009248 | S100A10/S100A11/S100A5/S100A2/S100A16/S100A13/ATP2B4/TNNC1/ANXA3/S100Z/ANXA1/MBL2/SLC24A4/ANXA2/CLEC4M | 15 |
| KEGG_SMALL_CELL_LUNG_CANCER | KEGG_SMALL_CELL_LUNG_CANCER | KEGG_SMALL_CELL_LUNG_CANCER | 15/1438 | 84/23056 | 0.1785714 | 2.863103 | 4.411959 | 0.0001964 | 0.0014385 | 0.0009248 | LAMC2/PTGS2/LAMB3/ITGA6/FN1/RARB/LAMB2/ITGA2/LAMA4/LAMA2/TRAF1/BIRC3/NFKBIA/ITGA3/COL4A6 | 15 |
| LEE_NEURAL_CREST_STEM_CELL_DN | LEE_NEURAL_CREST_STEM_CELL_DN | LEE_NEURAL_CREST_STEM_CELL_DN | 19/1438 | 122/23056 | 0.1557377 | 2.497002 | 4.275792 | 0.0001966 | 0.0014385 | 0.0009248 | EPHA2/NUAK2/EFEMP1/ACKR3/SLIT2/PLK2/DSP/NOTCH1/HTRA1/CD82/PRSS23/NAV3/FOS/GDF15/COL9A3/SAT1/SSX1/COL4A6/COL4A5 | 19 |
| MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | 19/1438 | 122/23056 | 0.1557377 | 2.497002 | 4.275792 | 0.0001966 | 0.0014385 | 0.0009248 | FBLIM1/MLPH/SPP1/PDGFC/TNFRSF21/PDK4/CLU/NIPAL2/HAS2/TPM2/SFTPD/PPP1R3C/PRSS23/MMP3/ANPEP/CLDN7/ACSF2/DSG2/TFAP2C | 19 |
| CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | 20/1438 | 132/23056 | 0.1515152 | 2.429300 | 4.247363 | 0.0001979 | 0.0014474 | 0.0009305 | VCAM1/ITGA6/EREG/SPP1/GDNF/ADAM19/TPBG/GJA1/THBS2/HAS2/APBB1IP/CASP4/HMGA2/PHLDA1/LUM/NFKBIA/TNFAIP2/BNC1/TGFB1/KCNN4 | 20 |
| GOBP_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT | GOBP_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT | GOBP_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | TNFRSF1B/CCN1/TGFB2/SLIT2/LEF1/FOXC1/NOTCH1/CRYAB/TNFRSF1A/BMP4 | 10 |
| GOBP_INTERMEDIATE_FILAMENT_ORGANIZATION | GOBP_INTERMEDIATE_FILAMENT_ORGANIZATION | GOBP_INTERMEDIATE_FILAMENT_ORGANIZATION | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | TCHH/DES/DSP/SHH/EPPK1/KRT13/KRT15/KRT19/KRT17/BFSP1 | 10 |
| GOBP_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | RUNX3/ZC3H12A/BCL6/HFE/GLI3/SHH/CD274/ANXA1/IL4R/RUNX1 | 10 |
| GOBP_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | GOBP_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | GOBP_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | ZC3H12A/PTPN22/IL1B/IL15/STING1/MICB/TNFAIP3/DDX58/IL12RB1/APOBEC3G | 10 |
| HP_ARTHROPATHY | HP_ARTHROPATHY | HP_ARTHROPATHY | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | PTPN22/HJV/PRG4/NLRP3/HFE/TNFAIP3/TNFRSF1A/MMP14/MMP2/BMP2 | 10 |
| MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER | MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER | MCGARVEY_SILENCED_BY_METHYLATION_IN_COLON_CANCER | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | EFEMP1/EPHA4/FOXL2/LEF1/HDGFL1/ADAMTS15/ADAMTS18/ICAM1/GATA5/MOV10L1 | 10 |
| PID_UPA_UPAR_PATHWAY | PID_UPA_UPAR_PATHWAY | PID_UPA_UPAR_PATHWAY | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | FN1/ITGB5/SERPINE1/PLAU/MMP3/ITGA5/ITGA3/ELANE/TGFB1/FPR1 | 10 |
| REACTOME_NCAM1_INTERACTIONS | REACTOME_NCAM1_INTERACTIONS | REACTOME_NCAM1_INTERACTIONS | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | AGRN/COL3A1/COL5A2/COL6A3/GDNF/COL5A1/PRNP/COL9A3/COL6A2/COL4A5 | 10 |
| WP_TNFRELATED_WEAK_INDUCER_OF_APOPTOSIS_TWEAK_SIGNALING_PATHWAY | WP_TNFRELATED_WEAK_INDUCER_OF_APOPTOSIS_TWEAK_SIGNALING_PATHWAY | WP_TNFRELATED_WEAK_INDUCER_OF_APOPTOSIS_TWEAK_SIGNALING_PATHWAY | 10/1438 | 42/23056 | 0.2380952 | 3.817471 | 4.713487 | 0.0002020 | 0.0014700 | 0.0009450 | TRIM63/CASP8/IL6/TRAF1/NFKB2/BIRC3/NFKBIA/TNFRSF12A/CCL5/RELB | 10 |
| HP_SYNOSTOSIS_OF_JOINTS | HP_SYNOSTOSIS_OF_JOINTS | HP_SYNOSTOSIS_OF_JOINTS | 25/1438 | 184/23056 | 0.1358696 | 2.178448 | 4.139250 | 0.0002021 | 0.0014700 | 0.0009450 | PTCH2/TBX15/CYP26B1/FN1/FGFRL1/FGFR3/SH3TC2/TFAP2A/BMPER/GLI3/TMEM270/GDF6/COLEC10/TPM2/DKK1/FGFR2/GLI1/SMAD6/SALL1/MAF/MEOX1/NOG/PIEZO2/RRAS/GPC4 | 25 |
| GOBP_REGULATION_OF_CELL_KILLING | GOBP_REGULATION_OF_CELL_KILLING | GOBP_REGULATION_OF_CELL_KILLING | 17/1438 | 103/23056 | 0.1650485 | 2.646286 | 4.318753 | 0.0002057 | 0.0014957 | 0.0009616 | MR1/CFH/PTPRC/TGFB2/CXCL6/IL7R/F2RL1/HLA-E/MICA/RAET1E/KLRD1/KLRC4-KLRK1/NCKAP1L/ICAM1/IL12RB1/NECTIN2/IL11 | 17 |
| GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | 11/1438 | 50/23056 | 0.2200000 | 3.527344 | 4.614057 | 0.0002089 | 0.0015165 | 0.0009749 | RUNX3/ITPKB/NLRP3/TGFBR2/GLI3/SHH/ANXA1/NCKAP1L/IL4R/IL12RB1/RUNX1 | 11 |
| GOBP_PROSTANOID_METABOLIC_PROCESS | GOBP_PROSTANOID_METABOLIC_PROCESS | GOBP_PROSTANOID_METABOLIC_PROCESS | 11/1438 | 50/23056 | 0.2200000 | 3.527344 | 4.614057 | 0.0002089 | 0.0015165 | 0.0009749 | EDN2/PTGS2/PLA2G4A/IL1B/EDN1/ANXA1/PTGR1/PTGS1/AKR1C3/TNFRSF1A/PTGIS | 11 |
| GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY | GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY | GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_SIGNALING_PATHWAY | 11/1438 | 50/23056 | 0.2200000 | 3.527344 | 4.614057 | 0.0002089 | 0.0015165 | 0.0009749 | NRP2/KDR/ADAMTS3/VEGFC/FOXC1/TSPAN12/JCAD/NRP1/FLT3/FLT1/PRKD1 | 11 |
| HP_ABNORMALITY_OF_THE_METACARPAL_BONES | HP_ABNORMALITY_OF_THE_METACARPAL_BONES | HP_ABNORMALITY_OF_THE_METACARPAL_BONES | 27/1438 | 206/23056 | 0.1310680 | 2.101462 | 4.095571 | 0.0002098 | 0.0015222 | 0.0009786 | PTCH2/PTPN22/PRG4/COL3A1/TWIST2/CD96/FGFRL1/FGFR3/FAT4/SPARC/HFE/RUNX2/GLI3/SHH/TRPS1/EXT1/NOTCH1/MMP14/FBN1/SALL1/MMP2/NOG/KCNJ2/BMP2/COL9A3/IL2RB/BGN | 27 |
| MIKKELSEN_IPS_LCP_WITH_H3K4ME3 | MIKKELSEN_IPS_LCP_WITH_H3K4ME3 | MIKKELSEN_IPS_LCP_WITH_H3K4ME3 | 24/1438 | 174/23056 | 0.1379310 | 2.211501 | 4.137191 | 0.0002132 | 0.0015461 | 0.0009939 | C1orf54/GPA33/CAPG/IL17RC/SLC12A8/SPON2/GPSM3/GPR20/MMRN2/TSPAN32/ALDH3B1/VWA5A/ROBO4/C1RL/TNS2/SOAT2/SELPLG/LRCOL1/SLC28A1/CD68/IFI35/EBI3/KCNN4/EMP3 | 24 |
| GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS | 18/1438 | 113/23056 | 0.1592920 | 2.553990 | 4.270872 | 0.0002148 | 0.0015551 | 0.0009997 | IFI16/NMI/PPARG/CD96/PARP14/TRIM38/HLA-E/MICA/MICB/TNFAIP3/AHR/HTRA1/CARD16/KLRD1/NLRC5/DHX58/IL4I1/USP18 | 18 |
| REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | 18/1438 | 113/23056 | 0.1592920 | 2.553990 | 4.270872 | 0.0002148 | 0.0015551 | 0.0009997 | TGFA/IL1RAP/FGFR3/EPGN/EREG/BTC/FGF5/EGF/HBEGF/FGF18/IER3/PDGFA/MET/FGF20/FGFR2/FLT3/RAC2/PDGFB | 18 |
| RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_DN | 18/1438 | 113/23056 | 0.1592920 | 2.553990 | 4.270872 | 0.0002148 | 0.0015551 | 0.0009997 | IL22RA1/S100A2/CYP26B1/IL1A/GPR39/CDCP1/PTP4A1/PERP/CAV1/PTGS1/MMP1/AJUBA/PLEK2/EHD4/PAQR5/BNC1/KRT17/CARD10 | 18 |
| GOBP_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | GOBP_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | GOBP_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | 16/1438 | 94/23056 | 0.1702128 | 2.729086 | 4.332413 | 0.0002174 | 0.0015730 | 0.0010112 | PTGS2/SLIT2/KDR/PLK2/ADTRP/EPHB4/ANXA1/KLF4/NOTCH1/JCAD/NRP1/MMRN2/THBS1/HMOX1/CARD10/SRPX2 | 16 |
| GOBP_EAR_MORPHOGENESIS | GOBP_EAR_MORPHOGENESIS | GOBP_EAR_MORPHOGENESIS | 19/1438 | 123/23056 | 0.1544715 | 2.476701 | 4.235151 | 0.0002191 | 0.0015849 | 0.0010189 | PRRX1/OSR1/WNT5A/NKX3-2/TFAP2A/EDN1/TBX18/HOXA1/HOXA2/FZD6/CTHRC1/ITGA8/FGFR2/HMX3/SIX1/SIX4/ALDH1A3/NOG/SOX9 | 19 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | 20/1438 | 133/23056 | 0.1503759 | 2.411034 | 4.209030 | 0.0002195 | 0.0015852 | 0.0010191 | SULT1C2/TMEM37/DPP4/TFPI/NRP2/CXCL1/CXCL5/ANXA3/ELL2/SPARC/ADTRP/SYNJ2/PYROXD2/MMP1/BHLHE41/NUPR1/MAF/SLFN13/KLF2/APOE | 20 |
| GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 13/1438 | 67/23056 | 0.1940299 | 3.110954 | 4.462831 | 0.0002197 | 0.0015852 | 0.0010191 | PTPRC/CD96/BCL6/IL7R/HFE/HLA-E/MICA/AHR/KLRD1/NCKAP1L/FOXF1/IL4I1/HMOX1 | 13 |
| GOBP_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 13/1438 | 67/23056 | 0.1940299 | 3.110954 | 4.462831 | 0.0002197 | 0.0015852 | 0.0010191 | ZC3H12A/PTGS2/PPARG/SULT1E1/CDS1/RREB1/RARRES2/SIX1/ZFP36L1/METRNL/ZFP36/BMP2/CEBPB | 13 |
| GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION | 13/1438 | 67/23056 | 0.1940299 | 3.110954 | 4.462831 | 0.0002197 | 0.0015852 | 0.0010191 | RUNX3/ZC3H12A/ITPKB/NLRP3/TGFBR2/BCL6/GLI3/SHH/ANXA1/NCKAP1L/IL4R/IL12RB1/RUNX1 | 13 |
| RIGGINS_TAMOXIFEN_RESISTANCE_UP | RIGGINS_TAMOXIFEN_RESISTANCE_UP | RIGGINS_TAMOXIFEN_RESISTANCE_UP | 13/1438 | 67/23056 | 0.1940299 | 3.110954 | 4.462831 | 0.0002197 | 0.0015852 | 0.0010191 | SLCO2A1/LRRC15/PTP4A1/OGFRL1/LAMA4/ALDH3B1/SERPINA1/TPM1/KRT13/COLEC12/MSN/STARD8/GPC4 | 13 |
| GHANDHI_DIRECT_IRRADIATION_DN | GHANDHI_DIRECT_IRRADIATION_DN | GHANDHI_DIRECT_IRRADIATION_DN | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | S1PR1/BRINP3/PRDM6/MDFI/FZD4/NFE2/HOXB3/ELANE/MN1 | 9 |
| GOBP_MAINTENANCE_OF_BLOOD_BRAIN_BARRIER | GOBP_MAINTENANCE_OF_BLOOD_BRAIN_BARRIER | GOBP_MAINTENANCE_OF_BLOOD_BRAIN_BARRIER | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | PTGS2/CLDN1/GJA1/LAMA2/IL6/ANGPT1/VCL/PECAM1/MBP | 9 |
| GOBP_REGULATION_OF_ENDOCRINE_PROCESS | GOBP_REGULATION_OF_ENDOCRINE_PROCESS | GOBP_REGULATION_OF_ENDOCRINE_PROCESS | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | AGT/FOXL2/DAB2/F2RL1/CRHBP/BMP6/GJA1/INHBA/C1QTNF1 | 9 |
| HP_ABNORMAL_LACRIMAL_DUCT_MORPHOLOGY | HP_ABNORMAL_LACRIMAL_DUCT_MORPHOLOGY | HP_ABNORMAL_LACRIMAL_DUCT_MORPHOLOGY | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | COL3A1/FOXL2/FGFR3/TFAP2A/FGFR2/GRIP1/FREM2/SIX1/SIX5 | 9 |
| HP_CARDIOVASCULAR_CALCIFICATION | HP_CARDIOVASCULAR_CALCIFICATION | HP_CARDIOVASCULAR_CALCIFICATION | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | LDLRAP1/GALNT3/SLC34A2/NT5E/NOTCH1/FBN1/SMAD6/GATA5/PDGFB | 9 |
| HP_CLUBBING_OF_FINGERS | HP_CLUBBING_OF_FINGERS | HP_CLUBBING_OF_FINGERS | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | HSPG2/FCGR2A/NLRP3/SLCO2A1/SLC34A2/DSP/PSMB8/NCKAP1L/TGFB1 | 9 |
| WP_SIGNAL_TRANSDUCTION_THROUGH_IL1R | WP_SIGNAL_TRANSDUCTION_THROUGH_IL1R | WP_SIGNAL_TRANSDUCTION_THROUGH_IL1R | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | TGFB2/IL1R1/IL1A/IL1B/IRAK2/IL1RAP/IL6/NFKBIA/TGFB1 | 9 |
| YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_15 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_15 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_15 | 9/1438 | 35/23056 | 0.2571429 | 4.122869 | 4.768480 | 0.0002239 | 0.0016084 | 0.0010340 | GBP4/SEMA3B/PLAC8/SEMA3C/COL14A1/LUM/POSTN/ITM2A/COL4A5 | 9 |
| HP_ABNORMALITY_OF_THE_ELBOW | HP_ABNORMALITY_OF_THE_ELBOW | HP_ABNORMALITY_OF_THE_ELBOW | 30/1438 | 240/23056 | 0.1250000 | 2.004173 | 4.033188 | 0.0002248 | 0.0016137 | 0.0010374 | HSPG2/TBX15/CYP26B1/COL5A2/COL6A3/COL7A1/WNT5A/CD96/FGFR3/TFAP2A/PSMB8/COL12A1/TENT5A/GJA1/LAMA2/CSGALNACT1/COLEC10/TPM2/COL27A1/COL5A1/FGFR2/ITGA7/GLI1/FBN1/SMAD6/COL1A1/NOG/COL9A3/COL6A2/BGN | 30 |
| RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP | 14/1438 | 76/23056 | 0.1842105 | 2.953517 | 4.399500 | 0.0002265 | 0.0016206 | 0.0010418 | PTPRC/SEL1L3/CXCL8/ITPR3/CRYBG1/VNN2/ADAM28/CA1/MAP3K8/AHNAK/BIRC3/GLIPR1/CEBPB/IL13RA1 | 14 |
| COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_DN | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_DN | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_DN | 8/1438 | 28/23056 | 0.2857143 | 4.580966 | 4.889960 | 0.0002265 | 0.0016206 | 0.0010418 | PRRX1/FN1/BHLHE40/SPP1/TGFBI/GPNMB/EDNRB/ANXA2 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION | 8/1438 | 28/23056 | 0.2857143 | 4.580966 | 4.889960 | 0.0002265 | 0.0016206 | 0.0010418 | GBP1/PTPRC/CD34/TNFAIP3/SFTPD/NAV3/ZFP36/PRNP | 8 |
| GOMF_CHEMOREPELLENT_ACTIVITY | GOMF_CHEMOREPELLENT_ACTIVITY | GOMF_CHEMOREPELLENT_ACTIVITY | 8/1438 | 28/23056 | 0.2857143 | 4.580966 | 4.889960 | 0.0002265 | 0.0016206 | 0.0010418 | DPP4/SEMA3B/SEMA5A/SEMA3C/SEMA3A/SEMA3D/APOA1/SEMA6B | 8 |
| PID_WNT_SIGNALING_PATHWAY | PID_WNT_SIGNALING_PATHWAY | PID_WNT_SIGNALING_PATHWAY | 8/1438 | 28/23056 | 0.2857143 | 4.580966 | 4.889960 | 0.0002265 | 0.0016206 | 0.0010418 | WNT5A/FZD1/FZD6/CTHRC1/FZD8/DKK1/FZD4/WNT7B | 8 |
| REACTOME_TRP_CHANNELS | REACTOME_TRP_CHANNELS | REACTOME_TRP_CHANNELS | 8/1438 | 28/23056 | 0.2857143 | 4.580966 | 4.889960 | 0.0002265 | 0.0016206 | 0.0010418 | MCOLN2/TRPM8/TRPC3/TRPA1/TRPM6/TRPC4/MLKL/TRPV2 | 8 |
| ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_UP | 8/1438 | 28/23056 | 0.2857143 | 4.580966 | 4.889960 | 0.0002265 | 0.0016206 | 0.0010418 | CFH/GJA1/IFITM3/C1S/C1R/SOX9/MX1/APOL1 | 8 |
| GOBP_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | GOBP_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY | 17/1438 | 104/23056 | 0.1634615 | 2.620841 | 4.272687 | 0.0002318 | 0.0016568 | 0.0010651 | S1PR1/AGT/HRH1/NPR3/F2RL1/EDN1/HCRTR2/GPR20/CCKBR/P2RY2/C3AR1/EDNRB/C5AR1/FPR1/ADRA1D/TGM2/LPAR4 | 17 |
| GOBP_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | GOBP_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | GOBP_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 17/1438 | 104/23056 | 0.1634615 | 2.620841 | 4.272687 | 0.0002318 | 0.0016568 | 0.0010651 | ZC3H12A/PTGS2/PTPN14/IL1B/SP100/GLI3/CD36/MDFIC/SHH/ANGPT1/TCF7L2/BAG3/PRKD1/BMP4/JUP/TGFB1/MX2 | 17 |
| GOBP_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | GOBP_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | GOBP_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING | 21/1438 | 144/23056 | 0.1458333 | 2.338201 | 4.154564 | 0.0002390 | 0.0017070 | 0.0010974 | TGFB2/AGT/FN1/SERPINE2/KDR/EGF/PDGFC/F2RL1/EDN1/PDGFA/ANGPT1/TEK/IGF1/FLT3/FLT1/ZFP36L1/LTK/CCL5/CSF3/SOX9/PDGFB | 21 |
| GOBP_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION | GOBP_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION | GOBP_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION | 12/1438 | 59/23056 | 0.2033898 | 3.261026 | 4.484875 | 0.0002398 | 0.0017117 | 0.0011004 | TGFA/IL1A/IL1B/WNT5A/EPGN/EREG/BTC/EGF/EDN1/STRA8/IGF1/PDGFB | 12 |
| GOMF_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 46/1438 | 429/23056 | 0.1072261 | 1.719197 | 3.878084 | 0.0002445 | 0.0017442 | 0.0011213 | SLC1A7/MCOLN2/KCNN3/ATP2B4/TMEM37/KCNE4/TRPM8/SLC12A8/CLDN16/SLC34A2/SLC4A4/TRPC3/SLC12A7/SLC6A7/ITPR3/SLC22A1/AQP1/PKD1L1/TRPA1/NIPAL2/TMC1/TRPM6/SLC5A12/LRRC55/CATSPER1/SLC6A13/CACNA2D4/KCNA5/SCNN1A/KCNH3/TPCN1/TRPC4/SLC10A2/SLC24A4/ANXA2/HCN4/SLC28A1/ORAI3/TRPV2/KCNJ2/CACNA1A/SCN1B/KCNK6/KCNN4/KCNA7/CACNG6 | 46 |
| HP_CONGESTIVE_HEART_FAILURE | HP_CONGESTIVE_HEART_FAILURE | HP_CONGESTIVE_HEART_FAILURE | 29/1438 | 230/23056 | 0.1260870 | 2.021600 | 4.015912 | 0.0002446 | 0.0017446 | 0.0011216 | HJV/DES/PPARG/FGFR3/DSP/HFE/PSMB8/GJA1/CCN2/CITED2/TMEM270/EPHB4/CAV1/FLNC/MYPN/VCL/BAG3/EFEMP2/FOS/FBLN5/ACTC1/FBN1/TPM1/JUP/CAVIN1/COL1A1/GATA6/SCN1B/BMP2 | 29 |
| HP_ABNORMALITY_OF_THE_UTERUS | HP_ABNORMALITY_OF_THE_UTERUS | HP_ABNORMALITY_OF_THE_UTERUS | 28/1438 | 219/23056 | 0.1278539 | 2.049930 | 4.026401 | 0.0002461 | 0.0017543 | 0.0011277 | COL3A1/COL5A2/RARB/TGFBR2/FOXL2/FGFRL1/FGFR3/RREB1/GLI3/PDGFRL/COL5A1/ITGA8/FGFR2/WT1/PTPRJ/MYRF/STAT6/GRIP1/FREM2/DACT1/BNC1/SALL1/FOXF1/COL1A1/SOX9/NDP/COL4A6/COL4A5 | 28 |
| GOBP_NEGATIVE_REGULATION_OF_TRANSPORT | GOBP_NEGATIVE_REGULATION_OF_TRANSPORT | GOBP_NEGATIVE_REGULATION_OF_TRANSPORT | 49/1438 | 466/23056 | 0.1051502 | 1.685913 | 3.857965 | 0.0002479 | 0.0017662 | 0.0011354 | TNFRSF1B/PTGS2/OSR1/IL1B/KCNE4/SERPINE2/SP100/EPHA3/OSTN/HES1/EGF/CRHBP/ADTRP/EDN1/GJA1/TRDN/INHBA/HECW1/CD36/MDFIC/CAV1/TCAF2/SHH/STC1/ANGPT1/ANXA1/NOTCH1/BAG3/CRYAB/APOC3/TNFRSF1A/SPX/NCKAP1L/BEST3/PRKD1/THBS1/ANXA2/RHBDF1/RRAD/FOXF1/RHBDF2/CNN2/APOE/IL11/SIRPA/REM1/LIF/HMOX1/GABRE | 49 |
| GOBP_POSITIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | 10/1438 | 43/23056 | 0.2325581 | 3.728693 | 4.619091 | 0.0002487 | 0.0017689 | 0.0011371 | PTGS2/AGT/IL1B/EDN1/SOD2/CD36/CLU/KLF4/KLRC4-KLRK1/KLF2 | 10 |
| GOBP_REGULATION_OF_COLLAGEN_METABOLIC_PROCESS | GOBP_REGULATION_OF_COLLAGEN_METABOLIC_PROCESS | GOBP_REGULATION_OF_COLLAGEN_METABOLIC_PROCESS | 10/1438 | 43/23056 | 0.2325581 | 3.728693 | 4.619091 | 0.0002487 | 0.0017689 | 0.0011371 | ERRFI1/FAP/ITGA2/CCN2/IL6/CREB3L1/BMP4/SERPINB7/TGFB1/RUNX1 | 10 |
| MA_MYELOID_DIFFERENTIATION_DN | MA_MYELOID_DIFFERENTIATION_DN | MA_MYELOID_DIFFERENTIATION_DN | 10/1438 | 43/23056 | 0.2325581 | 3.728693 | 4.619091 | 0.0002487 | 0.0017689 | 0.0011371 | VCAM1/PTPN22/HBEGF/PLA2G7/CITED2/NOTCH1/FOS/CES1/SERPINB2/MID1 | 10 |
| HP_ABNORMAL_ERYTHROCYTE_SEDIMENTATION_RATE | HP_ABNORMAL_ERYTHROCYTE_SEDIMENTATION_RATE | HP_ABNORMAL_ERYTHROCYTE_SEDIMENTATION_RATE | 11/1438 | 51/23056 | 0.2156863 | 3.458180 | 4.532542 | 0.0002515 | 0.0017870 | 0.0011488 | PTPN22/NLRP3/CASP10/SPP1/STING1/PSMB8/PSMB9/IL6/TNFRSF1A/TGFB1/IL2RB | 11 |
| KOHOUTEK_CCNT1_TARGETS | KOHOUTEK_CCNT1_TARGETS | KOHOUTEK_CCNT1_TARGETS | 11/1438 | 51/23056 | 0.2156863 | 3.458180 | 4.532542 | 0.0002515 | 0.0017870 | 0.0011488 | S100A13/DNER/COL7A1/PXDC1/AQP3/HTRA1/CRYAB/KRT18/AHNAK2/CD68/ITGB4 | 11 |
| HP_ABNORMAL_URINE_CYTOLOGY | HP_ABNORMAL_URINE_CYTOLOGY | HP_ABNORMAL_URINE_CYTOLOGY | 22/1438 | 155/23056 | 0.1419355 | 2.275705 | 4.110014 | 0.0002550 | 0.0018106 | 0.0011640 | PTPN22/CFH/ITGA6/NABP1/FN1/IL17RC/CLDN16/SLC34A2/SPP1/CFI/ITGA2/CD109/WT1/YAP1/APOA1/MYO1E/ITGB4/C3/THBD/HMOX1/COL4A6/COL4A5 | 22 |
| GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | GOBP_IMMUNE_RESPONSE_REGULATING_SIGNALING_PATHWAY | 50/1438 | 479/23056 | 0.1043841 | 1.673630 | 3.842471 | 0.0002563 | 0.0018151 | 0.0011669 | ZC3H12A/GBP1/GFI1/PTPN22/CTSS/PTPRC/LAX1/RAB7B/NMI/IRAK2/TXK/TEC/TNIP3/DDX60/TLR3/F2RL1/MOG/MICB/TNFRSF21/TNFAIP3/CD36/CAV1/DDX58/MBL2/PLPP4/NLRP6/PTPRJ/SLC15A3/BIRC3/C3AR1/KLRD1/KLRC4-KLRK1/NCKAP1L/TESPA1/OASL/NFKBIA/RNF135/CCR7/DHX58/IFI35/COLEC12/CD22/PSG9/KCNN4/NECTIN2/C5AR1/FPR1/PRNP/NFATC2/ICOSLG | 50 |
| REACTOME_NEUTROPHIL_DEGRANULATION | REACTOME_NEUTROPHIL_DEGRANULATION | REACTOME_NEUTROPHIL_DEGRANULATION | 50/1438 | 479/23056 | 0.1043841 | 1.673630 | 3.842471 | 0.0002563 | 0.0018151 | 0.0011669 | TNFRSF1B/CDA/FUCA1/CD53/CTSS/S100A11/FCGR2A/PTPRC/TMEM63A/MME/PLD1/CXCL1/PLAC8/IQGAP2/STING1/DOCK2/SERPINB1/DSP/HLA-C/VNN1/FUCA2/CD36/GSDMD/B4GALT1/GSN/ALOX5/PLAU/VCL/CD44/PTPRJ/ALDH3B1/C3AR1/NCKAP1L/GLIPR1/PYGL/SERPINA1/ANXA2/ANPEP/COTL1/CRISPLD2/CD68/JUP/PECAM1/ELANE/CNN2/C3/GMFG/C5AR1/FPR1/SIRPA | 50 |
| CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | CHIARETTI_ACUTE_LYMPHOBLASTIC_LEUKEMIA_ZAP70 | 13/1438 | 68/23056 | 0.1911765 | 3.065205 | 4.398669 | 0.0002564 | 0.0018151 | 0.0011669 | TNFRSF1B/CASP10/CASP8/LRRC15/JCHAIN/CCN2/TRIP6/MYBL1/ITGA5/IL32/LAT/RRAD/IL27RA | 13 |
| GOBP_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION | 13/1438 | 68/23056 | 0.1911765 | 3.065205 | 4.398669 | 0.0002564 | 0.0018151 | 0.0011669 | TNFRSF21/GPNMB/SHH/IDO1/CD274/PDCD1LG2/SFTPD/LRRC32/BMP4/IL4I1/PRNP/SDC4/CEBPB | 13 |
| GOBP_REGULATION_OF_PROTEIN_MATURATION | GOBP_REGULATION_OF_PROTEIN_MATURATION | GOBP_REGULATION_OF_PROTEIN_MATURATION | 13/1438 | 68/23056 | 0.1911765 | 3.065205 | 4.398669 | 0.0002564 | 0.0018151 | 0.0011669 | S100A10/SERPINE2/NKD2/SERPINE1/GAS1/GSN/CARD16/MMP14/THBS1/ANXA2/PRNP/RUNX1/MYH9 | 13 |
| LINDVALL_IMMORTALIZED_BY_TERT_UP | LINDVALL_IMMORTALIZED_BY_TERT_UP | LINDVALL_IMMORTALIZED_BY_TERT_UP | 13/1438 | 68/23056 | 0.1911765 | 3.065205 | 4.398669 | 0.0002564 | 0.0018151 | 0.0011669 | EFEMP1/EREG/TAPBP/CITED2/EXT1/PTGS1/DKK1/PAPSS2/SLC22A18/KRT18/LUM/BMP4/KDELR3 | 13 |
| GOBP_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 15/1438 | 86/23056 | 0.1744186 | 2.796520 | 4.304820 | 0.0002570 | 0.0018160 | 0.0011674 | EPHA2/TGFBR2/WNT5A/SLC7A11/GJA1/CITED2/PITX3/PLAAT3/CRYAB/BMP4/MAF/SIX5/BFSP1/BIRC7/WNT7B | 15 |
| HP_REDUNDANT_SKIN | HP_REDUNDANT_SKIN | HP_REDUNDANT_SKIN | 15/1438 | 86/23056 | 0.1744186 | 2.796520 | 4.304820 | 0.0002570 | 0.0018160 | 0.0011674 | TBX15/COL3A1/TWIST2/CD96/FGFR3/ADAMTS2/FOXC1/TMEM270/FGF20/TRPS1/EXT1/FGFR2/EFEMP2/FBLN5/RIN2 | 15 |
| KEGG_TGF_BETA_SIGNALING_PATHWAY | KEGG_TGF_BETA_SIGNALING_PATHWAY | KEGG_TGF_BETA_SIGNALING_PATHWAY | 15/1438 | 86/23056 | 0.1744186 | 2.796520 | 4.304820 | 0.0002570 | 0.0018160 | 0.0011674 | TGFB2/LTBP1/TGFBR2/FST/BMP6/ID4/THBS2/INHBA/GDF6/BMP4/THBS1/SMAD6/NOG/TGFB1/BMP2 | 15 |
| NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON | NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON | NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON | 38/1438 | 334/23056 | 0.1137725 | 1.824157 | 3.913039 | 0.0002570 | 0.0018160 | 0.0011674 | COPZ2/HOXB2/HOXB3/HOXB7/HOXB13/TTLL6/GIP/GNGT2/DLX4/DLX3/ITGA3/SGCA/COL1A1/TMEM92/ACSF2/ABCC3/ANKFN1/NOG/MRC2/PECAM1/MILR1/WIPI1/ABCA8/ABCA9/ABCA6/ABCA10/KCNJ2/SOX9/GPRC5C/SLC16A5/LLGL2/ITGB4/TMC8/SOCS3/C1QTNF1/TSPAN10/SLC16A3/METRNL | 38 |
| DAZARD_RESPONSE_TO_UV_SCC_UP | DAZARD_RESPONSE_TO_UV_SCC_UP | DAZARD_RESPONSE_TO_UV_SCC_UP | 17/1438 | 105/23056 | 0.1619048 | 2.595880 | 4.227158 | 0.0002608 | 0.0018408 | 0.0011834 | PTGS2/IL1B/KYNU/ACKR2/CXCL8/CXCL1/CXCL3/CXCL2/ANXA3/CSF2/CITED2/IL6/ARHGDIB/FOS/ANXA2/DSG2/IL13RA1 | 17 |
| REACTOME_PI3K_AKT_SIGNALING_IN_CANCER | REACTOME_PI3K_AKT_SIGNALING_IN_CANCER | REACTOME_PI3K_AKT_SIGNALING_IN_CANCER | 17/1438 | 105/23056 | 0.1619048 | 2.595880 | 4.227158 | 0.0002608 | 0.0018408 | 0.0011834 | TGFA/FGFR3/EPGN/EREG/BTC/FGF5/EGF/HBEGF/FGF18/PDGFA/MET/FGF20/FGFR2/FLT3/FOXO1/RAC2/PDGFB | 17 |
| GOBP_POSITIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | 14/1438 | 77/23056 | 0.1818182 | 2.915160 | 4.341493 | 0.0002612 | 0.0018414 | 0.0011838 | BMP10/CYP26B1/EDN1/RBM24/SOD2/SHH/EFEMP2/IGF1/MMP14/BMP4/MYLK3/PIEZO1/MYOCD/TGFB1 | 14 |
| HP_CONGENITAL_HIP_DISLOCATION | HP_CONGENITAL_HIP_DISLOCATION | HP_CONGENITAL_HIP_DISLOCATION | 14/1438 | 77/23056 | 0.1818182 | 2.915160 | 4.341493 | 0.0002612 | 0.0018414 | 0.0011838 | AGRN/HSPG2/TBX15/COL3A1/COL5A2/COL12A1/TPM2/COL13A1/ITGA7/SIX1/SMAD6/COL1A1/PIEZO2/GPC4 | 14 |
| MIKKELSEN_ES_LCP_WITH_H3K4ME3 | MIKKELSEN_ES_LCP_WITH_H3K4ME3 | MIKKELSEN_ES_LCP_WITH_H3K4ME3 | 21/1438 | 145/23056 | 0.1448276 | 2.322076 | 4.118817 | 0.0002633 | 0.0018559 | 0.0011931 | TAS1R1/C1orf54/SLC12A8/SPON2/DDR1/GPSM3/GPR20/MMRN2/TSPAN32/ALDH3B1/VWA5A/ROBO4/TNS2/SOAT2/SELPLG/LRCOL1/CD68/SLC16A5/RHBDF2/EBI3/EMP3 | 21 |
| GOMF_SERINE_HYDROLASE_ACTIVITY | GOMF_SERINE_HYDROLASE_ACTIVITY | GOMF_SERINE_HYDROLASE_ACTIVITY | 26/1438 | 198/23056 | 0.1313131 | 2.105393 | 4.028882 | 0.0002643 | 0.0018618 | 0.0011969 | CTSS/DPP4/FAP/AADAC/CFI/PCSK1/HTRA4/PLAT/PCSK5/PLAU/TLL2/HTRA1/PRSS23/MMP10/MMP1/MMP3/C1S/C1R/C1RL/MMP14/RHBDF1/MMP2/CTRB1/RHBDF2/ELANE/KLK6 | 26 |
| HP_ABNORMAL_ODONTOID_TISSUE_MORPHOLOGY | HP_ABNORMAL_ODONTOID_TISSUE_MORPHOLOGY | HP_ABNORMAL_ODONTOID_TISSUE_MORPHOLOGY | 28/1438 | 220/23056 | 0.1272727 | 2.040612 | 3.999856 | 0.0002656 | 0.0018697 | 0.0012020 | LAMC2/LAMB3/TGFA/ITGB6/GALNT3/ITGA6/IL17RC/COL7A1/CLDN1/FGFR3/AMTN/ENAM/RREB1/RUNX2/TENT5A/GJA1/FAM20C/TMEM270/FGFR2/SERPINH1/MMP1/WNT10B/SLC24A4/DLX3/COL1A1/KCNJ2/ITGB4/TNFRSF11A | 28 |
| BIOCARTA_EICOSANOID_PATHWAY | BIOCARTA_EICOSANOID_PATHWAY | BIOCARTA_EICOSANOID_PATHWAY | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | PTGS2/PLA2G4A/PTGS1/ALOX5/ALOX5AP/PTGIS/CYSLTR1 | 7 |
| DESERT_EXTRACELLULAR_MATRIX_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | DESERT_EXTRACELLULAR_MATRIX_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | DESERT_EXTRACELLULAR_MATRIX_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | MUC13/F2RL1/PPIC/VNN1/LUM/FBN1/NECTIN2 | 7 |
| GOBP_AXONAL_FASCICULATION | GOBP_AXONAL_FASCICULATION | GOBP_AXONAL_FASCICULATION | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | EPHA4/EPHA3/SEMA5A/TNFRSF21/SEMA3A/NRP1/NCAM2 | 7 |
| GOBP_BRANCHING_INVOLVED_IN_SALIVARY_GLAND_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_SALIVARY_GLAND_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_SALIVARY_GLAND_MORPHOGENESIS | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | PDGFA/SEMA3C/SEMA3A/SHH/NRP1/FGFR2/TGM2 | 7 |
| GOCC_LAMELLIPODIUM_MEMBRANE | GOCC_LAMELLIPODIUM_MEMBRANE | GOCC_LAMELLIPODIUM_MEMBRANE | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | EPHA2/DPP4/FAP/CD44/PLEK2/CSPG4/PIEZO1 | 7 |
| HP_BLISTERING_BY_ANATOMICAL_LOCATION | HP_BLISTERING_BY_ANATOMICAL_LOCATION | HP_BLISTERING_BY_ANATOMICAL_LOCATION | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | LAMC2/LAMB3/ITGA6/COL7A1/MMP1/KRT17/ITGB4 | 7 |
| SESTO_RESPONSE_TO_UV_C3 | SESTO_RESPONSE_TO_UV_C3 | SESTO_RESPONSE_TO_UV_C3 | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | PTGS2/IL1B/CXCL8/HBEGF/IER3/PHLDA2/SOX9 | 7 |
| SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP | SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP | SMID_BREAST_CANCER_RELAPSE_IN_LUNG_UP | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | FOXD1/HAPLN1/MMP14/CSPG4/KRT17/MUC16/KLK6 | 7 |
| WP_STING_PATHWAY_IN_KAWASAKILIKE_DISEASE_AND_COVID19 | WP_STING_PATHWAY_IN_KAWASAKILIKE_DISEASE_AND_COVID19 | WP_STING_PATHWAY_IN_KAWASAKILIKE_DISEASE_AND_COVID19 | 7/1438 | 22/23056 | 0.3181818 | 5.101530 | 4.963943 | 0.0002687 | 0.0018828 | 0.0012104 | FCGR2A/IKBKE/NLRP3/IL1B/STING1/GSDMD/NFKBIA | 7 |
| GOMF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 20/1438 | 135/23056 | 0.1481481 | 2.375316 | 4.133393 | 0.0002690 | 0.0018842 | 0.0012113 | MCOLN2/ATP2B4/TMEM37/TRPM8/TRPC3/ITPR3/PKD1L1/TRPA1/TMC1/TRPM6/CATSPER1/CACNA2D4/TPCN1/TRPC4/SLC24A4/ANXA2/ORAI3/TRPV2/CACNA1A/CACNG6 | 20 |
| GOBP_ACTIN_FILAMENT_SEVERING | GOBP_ACTIN_FILAMENT_SEVERING | GOBP_ACTIN_FILAMENT_SEVERING | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | CAPG/SCIN/GSN/FMNL1/GMFG/MYH9 | 6 |
| GOBP_ACTIN_MYOSIN_FILAMENT_SLIDING | GOBP_ACTIN_MYOSIN_FILAMENT_SLIDING | GOBP_ACTIN_MYOSIN_FILAMENT_SLIDING | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | TNNC1/ACTC1/TPM1/MYH8/MYH4/MYH2 | 6 |
| GOBP_HEAT_GENERATION | GOBP_HEAT_GENERATION | GOBP_HEAT_GENERATION | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | PTGS2/IL1A/IL1B/ADRB2/EDNRB/TNFRSF11A | 6 |
| GOBP_METANEPHRIC_GLOMERULUS_DEVELOPMENT | GOBP_METANEPHRIC_GLOMERULUS_DEVELOPMENT | GOBP_METANEPHRIC_GLOMERULUS_DEVELOPMENT | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | CD34/OSR1/LAMB2/WT1/LHX1/PDGFB | 6 |
| GOBP_POSITIVE_REGULATION_OF_MYOBLAST_FUSION | GOBP_POSITIVE_REGULATION_OF_MYOBLAST_FUSION | GOBP_POSITIVE_REGULATION_OF_MYOBLAST_FUSION | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | CD53/IL4R/TNFSF14/GDF15/EHD2/NFATC2 | 6 |
| GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | OSR1/WWTR1/GDNF/YAP1/LHX1/LIF | 6 |
| GOCC_COSTAMERE | GOCC_COSTAMERE | GOCC_COSTAMERE | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | FLNC/VCL/AHNAK/KRT19/SDC4/SMPX | 6 |
| HP_ABNORMAL_RIGHT_ATRIUM_MORPHOLOGY | HP_ABNORMAL_RIGHT_ATRIUM_MORPHOLOGY | HP_ABNORMAL_RIGHT_ATRIUM_MORPHOLOGY | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | CITED2/FLNC/NOTCH1/MYPN/ACTC1/GATA6 | 6 |
| HP_ANTINEUTROPHIL_ANTIBODY_POSITIVITY | HP_ANTINEUTROPHIL_ANTIBODY_POSITIVITY | HP_ANTINEUTROPHIL_ANTIBODY_POSITIVITY | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | GFI1/CASP10/SPP1/STING1/FAS/ELANE | 6 |
| HP_ONYCHOLYSIS | HP_ONYCHOLYSIS | HP_ONYCHOLYSIS | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | COL7A1/HFE/HLA-C/FZD6/JUP/ITGA3 | 6 |
| HP_VAGINAL_ATRESIA | HP_VAGINAL_ATRESIA | HP_VAGINAL_ATRESIA | 6/1438 | 16/23056 | 0.3750000 | 6.012517 | 5.172838 | 0.0002709 | 0.0018866 | 0.0012128 | RSPO2/ITGA8/FGFR2/WT1/GRIP1/FREM2 | 6 |
| HP_SKIN_RASH | HP_SKIN_RASH | HP_SKIN_RASH | 19/1438 | 125/23056 | 0.1520000 | 2.437074 | 4.155055 | 0.0002711 | 0.0018873 | 0.0012133 | TNFRSF1B/PTPN22/FCGR2A/NLRP3/CASP10/IL17RC/SPP1/STING1/PSMB9/GJA1/TNFAIP3/STX11/IL6/TEK/APOA1/TNFRSF1A/EPB42/PSMB10/RUNX1 | 19 |
| HP_ABNORMAL_LYMPHOCYTE_MORPHOLOGY | HP_ABNORMAL_LYMPHOCYTE_MORPHOLOGY | HP_ABNORMAL_LYMPHOCYTE_MORPHOLOGY | 24/1438 | 177/23056 | 0.1355932 | 2.174018 | 4.043868 | 0.0002767 | 0.0019251 | 0.0012376 | TNFRSF1B/FUCA1/GFI1/PTPRC/CASP10/CASP8/SP110/ADAMTS3/SPP1/FAT4/IL7R/STING1/DOCK2/PSMB9/TNFAIP3/SAMD9/FAS/NFKB2/NCKAP1L/LAT/ELANE/CD70/RAC2/MSN | 24 |
| GOBP_RESPONSE_TO_CHEMOKINE | GOBP_RESPONSE_TO_CHEMOKINE | GOBP_RESPONSE_TO_CHEMOKINE | 16/1438 | 96/23056 | 0.1666667 | 2.672230 | 4.234478 | 0.0002789 | 0.0019388 | 0.0012464 | ZC3H12A/ACKR3/ACKR2/CCR3/SLIT2/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/FOXC1/EDN1/CCL26/CCL5/CCR7 | 16 |
| REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3 | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3 | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3 | 16/1438 | 96/23056 | 0.1666667 | 2.672230 | 4.234478 | 0.0002789 | 0.0019388 | 0.0012464 | RUNX3/ITGA4/WWTR1/HES1/SPP1/LEF1/PSMB8/PSMB9/CCN2/NOTCH1/TCF7L2/MAML2/YAP1/PSMB10/TGFB1/RUNX1 | 16 |
| GOCC_SECRETORY_GRANULE_MEMBRANE | GOCC_SECRETORY_GRANULE_MEMBRANE | GOCC_SECRETORY_GRANULE_MEMBRANE | 36/1438 | 312/23056 | 0.1153846 | 1.850005 | 3.898700 | 0.0002812 | 0.0019534 | 0.0012557 | TNFRSF1B/CD53/FCGR2A/PTPRC/TMEM63A/MME/PLD1/IQGAP2/STING1/SPARC/DSP/HLA-C/ITPR3/CD109/MOXD1/VNN1/TMEM184A/CD36/CAV2/CAV1/B4GALT1/PLAU/CD44/PTPRJ/ALDH3B1/C3AR1/NCKAP1L/GLIPR1/MFGE8/ANPEP/CD68/PECAM1/ATP8B3/C5AR1/FPR1/SIRPA | 36 |
| GOBP_MONOCYTE_DIFFERENTIATION | GOBP_MONOCYTE_DIFFERENTIATION | GOBP_MONOCYTE_DIFFERENTIATION | 9/1438 | 36/23056 | 0.2500000 | 4.008345 | 4.658869 | 0.0002822 | 0.0019562 | 0.0012576 | CSF1/IFI16/PPARG/IL31RA/CSF2/HOXA7/BMP4/ZFP36L1/MYH9 | 9 |
| GOBP_SALIVARY_GLAND_DEVELOPMENT | GOBP_SALIVARY_GLAND_DEVELOPMENT | GOBP_SALIVARY_GLAND_DEVELOPMENT | 9/1438 | 36/23056 | 0.2500000 | 4.008345 | 4.658869 | 0.0002822 | 0.0019562 | 0.0012576 | TGFB2/PDGFA/SEMA3C/SEMA3A/SHH/NRP1/FGFR2/TGFB1/TGM2 | 9 |
| GOMF_AMIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_AMIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_AMIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 9/1438 | 36/23056 | 0.2500000 | 4.008345 | 4.658869 | 0.0002822 | 0.0019562 | 0.0012576 | ABCG2/TAPBP/GJA1/AQP7/AQP3/SLC15A3/SLC47A1/SLC14A2/SLC14A1 | 9 |
| HP_ABNORMALITY_OF_IMMUNE_SERUM_PROTEIN_PHYSIOLOGY | HP_ABNORMALITY_OF_IMMUNE_SERUM_PROTEIN_PHYSIOLOGY | HP_ABNORMALITY_OF_IMMUNE_SERUM_PROTEIN_PHYSIOLOGY | 9/1438 | 36/23056 | 0.2500000 | 4.008345 | 4.658869 | 0.0002822 | 0.0019562 | 0.0012576 | PTPN22/CASP10/SP110/PSMB8/STX11/FAS/NFKBIA/IL12RB1/IL2RB | 9 |
| GOBP_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 25/1438 | 188/23056 | 0.1329787 | 2.132098 | 4.019789 | 0.0002829 | 0.0019586 | 0.0012591 | CSF1/TGFB2/ITPKB/COL3A1/HEG1/BCL6/ARHGAP24/F2RL1/MET/GPR20/NOTCH1/NRP1/SYNPO2L/EPS8L2/ARHGAP42/APOC3/APOA1/ARHGDIB/EPS8/IGF1/ITGA3/APOE/CYTH4/STARD8/LPAR4 | 25 |
| LEE_LIVER_CANCER_CIPROFIBRATE_UP | LEE_LIVER_CANCER_CIPROFIBRATE_UP | LEE_LIVER_CANCER_CIPROFIBRATE_UP | 12/1438 | 60/23056 | 0.2000000 | 3.206676 | 4.414101 | 0.0002829 | 0.0019586 | 0.0012591 | NIBAN1/SPON2/PLA2G7/NT5E/VNN1/CD36/PDK4/PLAT/FABP4/MFGE8/MT2A/TGM2 | 12 |
| MEISSNER_BRAIN_HCP_WITH_H3K4ME2_AND_H3K27ME3 | MEISSNER_BRAIN_HCP_WITH_H3K4ME2_AND_H3K27ME3 | MEISSNER_BRAIN_HCP_WITH_H3K4ME2_AND_H3K27ME3 | 12/1438 | 60/23056 | 0.2000000 | 3.206676 | 4.414101 | 0.0002829 | 0.0019586 | 0.0012591 | MCOLN2/LRRC15/SLC34A2/PPIC/TCP11/HOXA1/FLNC/LOXL2/GDF6/AQP3/ITGB4/IL27RA | 12 |
| GOBP_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | GOBP_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | GOBP_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 29/1438 | 232/23056 | 0.1250000 | 2.004173 | 3.964703 | 0.0002835 | 0.0019619 | 0.0012612 | CCN1/IFI16/PTGS2/NLRP3/CASP10/CASP8/PPARG/FOXL2/PSMB9/CCN2/PERP/AQP1/ASPH/KLF4/TNFSF15/GSN/FAS/NLRP6/CD44/BIRC3/CASP4/CASP1/CARD16/CRYAB/BLID/THBS1/UACA/TNFSF14/BIRC7 | 29 |
| HP_EMG_ABNORMALITY | HP_EMG_ABNORMALITY | HP_EMG_ABNORMALITY | 32/1438 | 266/23056 | 0.1203008 | 1.928828 | 3.929688 | 0.0002854 | 0.0019740 | 0.0012690 | AGRN/HSPG2/NEXN/CASQ1/DES/COL6A3/LAMB2/TNNC1/DOK7/HSPB3/SH3TC2/DSP/CAP2/COL12A1/LAMA4/LAMA2/SHH/TPM2/GAS1/MYPN/COL13A1/VCL/ANKRD1/BAG3/CRYAB/APOA1/ZIC2/ACTC1/TPM1/SGCA/DSG2/COL6A2 | 32 |
| HP_CLEFT_LIP | HP_CLEFT_LIP | HP_CLEFT_LIP | 27/1438 | 210/23056 | 0.1285714 | 2.061434 | 3.985218 | 0.0002874 | 0.0019870 | 0.0012773 | PTCH2/NUAK2/IL1B/WNT5A/FGFRL1/TFAP2A/GJA1/FAM20C/GLI3/SHH/FGF20/RSPO2/COLEC10/GAS1/ITGA8/ALX4/YAP1/GRIP1/FREM2/ZIC2/BMP4/FOXF1/JUP/MEOX1/DLX4/MID1/GPC4 | 27 |
| GOBP_CARDIAC_ATRIUM_MORPHOGENESIS | GOBP_CARDIAC_ATRIUM_MORPHOGENESIS | GOBP_CARDIAC_ATRIUM_MORPHOGENESIS | 8/1438 | 29/23056 | 0.2758621 | 4.423001 | 4.757093 | 0.0002958 | 0.0020388 | 0.0013107 | CCN1/TGFB2/BMP10/WNT5A/HEG1/NOTCH1/NOG/BMP2 | 8 |
| GOBP_LIVER_REGENERATION | GOBP_LIVER_REGENERATION | GOBP_LIVER_REGENERATION | 8/1438 | 29/23056 | 0.2758621 | 4.423001 | 4.757093 | 0.0002958 | 0.0020388 | 0.0013107 | CLDN1/IL6/GLI3/PTPN3/GLI1/SERPINA10/CEBPB/HMOX1 | 8 |
| GOMF_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING | GOMF_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING | GOMF_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING | 8/1438 | 29/23056 | 0.2758621 | 4.423001 | 4.757093 | 0.0002958 | 0.0020388 | 0.0013107 | HSPG2/LDLRAP1/DAB2/CLU/DKK1/APOC3/APOA1/APOE | 8 |
| GOMF_RECEPTOR_SERINE_THREONINE_KINASE_BINDING | GOMF_RECEPTOR_SERINE_THREONINE_KINASE_BINDING | GOMF_RECEPTOR_SERINE_THREONINE_KINASE_BINDING | 8/1438 | 29/23056 | 0.2758621 | 4.423001 | 4.757093 | 0.0002958 | 0.0020388 | 0.0013107 | BMP10/BMP3/BMP6/INHBA/BMP4/SMAD6/GDF15/BMP2 | 8 |
| PAL_PRMT5_TARGETS_DN | PAL_PRMT5_TARGETS_DN | PAL_PRMT5_TARGETS_DN | 8/1438 | 29/23056 | 0.2758621 | 4.423001 | 4.757093 | 0.0002958 | 0.0020388 | 0.0013107 | CCN1/VCAM1/IL1A/HLA-E/SERPINE1/FABP4/NUPR1/KRT17 | 8 |
| SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_PRE_TREATMENT_UP | SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_PRE_TREATMENT_UP | SALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_PRE_TREATMENT_UP | 8/1438 | 29/23056 | 0.2758621 | 4.423001 | 4.757093 | 0.0002958 | 0.0020388 | 0.0013107 | HLA-C/TREML1/IFITM3/KLRD1/OASL/CCL5/MYL9/MAP3K7CL | 8 |
| GOMF_PROTEASE_BINDING | GOMF_PROTEASE_BINDING | GOMF_PROTEASE_BINDING | 20/1438 | 136/23056 | 0.1470588 | 2.357850 | 4.096078 | 0.0002972 | 0.0020474 | 0.0013162 | ECM1/ADAMTSL4/IL1R1/DPP4/FAP/COL3A1/FN1/TNFAIP3/SERPINE1/TNFRSF10A/CARD16/VWF/SERPINA1/ANXA2/ITGA3/COL1A1/MBP/ELANE/CD70/PRNP | 20 |
| BOSCO_EPITHELIAL_DIFFERENTIATION_MODULE | BOSCO_EPITHELIAL_DIFFERENTIATION_MODULE | BOSCO_EPITHELIAL_DIFFERENTIATION_MODULE | 13/1438 | 69/23056 | 0.1884058 | 3.020782 | 4.335678 | 0.0002981 | 0.0020523 | 0.0013193 | ECM1/ELF3/TM4SF1/PTPN3/GPRC5A/KRT4/KRT18/CLDN7/KRT13/KRT17/SERPINB2/MUC16/NCCRP1 | 13 |
| GOBP_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 18/1438 | 116/23056 | 0.1551724 | 2.487938 | 4.143539 | 0.0002998 | 0.0020632 | 0.0013264 | ZC3H12A/TNFSF18/NLRP3/BCL6/LEF1/F2RL1/IL6/IFNE/ANXA1/APBB1IP/NCKAP1L/STAT6/LCP1/IL4R/ICAM1/IL12RB1/BCL3/RELB | 18 |
| GOBP_ORGANIC_HYDROXY_COMPOUND_CATABOLIC_PROCESS | GOBP_ORGANIC_HYDROXY_COMPOUND_CATABOLIC_PROCESS | GOBP_ORGANIC_HYDROXY_COMPOUND_CATABOLIC_PROCESS | 14/1438 | 78/23056 | 0.1794872 | 2.877786 | 4.284415 | 0.0003003 | 0.0020653 | 0.0013277 | SULT1E1/INPP4B/CYP39A1/MOXD1/SYNJ2/AKR1B10/AKR1C3/ALDH3B1/DIO2/CYP46A1/LDHD/CYP4F11/APOE/CYP24A1 | 14 |
| INGRAM_SHH_TARGETS_UP | INGRAM_SHH_TARGETS_UP | INGRAM_SHH_TARGETS_UP | 19/1438 | 126/23056 | 0.1507937 | 2.417732 | 4.115585 | 0.0003009 | 0.0020684 | 0.0013297 | MR1/NID1/TWIST2/HES1/PLAC8/SGMS2/SLC12A7/FOXD1/CCN2/TEK/KLF4/ALX4/GLI1/ZFP36L1/FBN1/NOG/THBD/CDC42EP1/GPC4 | 19 |
| GOBP_POSITIVE_REGULATION_OF_ORGAN_GROWTH | GOBP_POSITIVE_REGULATION_OF_ORGAN_GROWTH | GOBP_POSITIVE_REGULATION_OF_ORGAN_GROWTH | 11/1438 | 52/23056 | 0.2115385 | 3.391676 | 4.453041 | 0.0003012 | 0.0020684 | 0.0013297 | BMP10/EDN1/ZFPM2/NOTCH1/FGFR2/WT1/YAP1/YBX3/GLI1/IGF1/GATA6 | 11 |
| HP_ABNORMALITY_OF_THE_HUMERORADIAL_JOINT | HP_ABNORMALITY_OF_THE_HUMERORADIAL_JOINT | HP_ABNORMALITY_OF_THE_HUMERORADIAL_JOINT | 11/1438 | 52/23056 | 0.2115385 | 3.391676 | 4.453041 | 0.0003012 | 0.0020684 | 0.0013297 | TBX15/CYP26B1/COL5A2/CD96/TENT5A/COL27A1/COL5A1/FGFR2/SMAD6/COL1A1/NOG | 11 |
| GOBP_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION | GOBP_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION | GOBP_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION | 10/1438 | 44/23056 | 0.2272727 | 3.643950 | 4.527481 | 0.0003040 | 0.0020836 | 0.0013395 | TGFA/IL1A/IL1B/EPGN/EREG/BTC/EGF/EDN1/IGF1/PDGFB | 10 |
| LIU_TARGETS_OF_VMYB_VS_CMYB_DN | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | 10/1438 | 44/23056 | 0.2272727 | 3.643950 | 4.527481 | 0.0003040 | 0.0020836 | 0.0013395 | TM4SF1/ARHGAP24/CSF2/ADRB2/IL6/CSGALNACT1/S1PR3/NRIP3/PTPRJ/YBX3 | 10 |
| PARENT_MTOR_SIGNALING_DN | PARENT_MTOR_SIGNALING_DN | PARENT_MTOR_SIGNALING_DN | 10/1438 | 44/23056 | 0.2272727 | 3.643950 | 4.527481 | 0.0003040 | 0.0020836 | 0.0013395 | CRABP2/CXCL3/EREG/FGF5/ADAM19/MYL4/CNN1/BMP2/PDGFB/MAGEA9 | 10 |
| VANHARANTA_UTERINE_FIBROID_UP | VANHARANTA_UTERINE_FIBROID_UP | VANHARANTA_UTERINE_FIBROID_UP | 10/1438 | 44/23056 | 0.2272727 | 3.643950 | 4.527481 | 0.0003040 | 0.0020836 | 0.0013395 | COL3A1/COL5A2/FN1/MEST/LOXL2/SULF1/TRPS1/LTBP2/COL1A1/TFAP2C | 10 |
| KEGG_MAPK_SIGNALING_PATHWAY | KEGG_MAPK_SIGNALING_PATHWAY | KEGG_MAPK_SIGNALING_PATHWAY | 32/1438 | 267/23056 | 0.1198502 | 1.921604 | 3.906532 | 0.0003053 | 0.0020917 | 0.0013447 | PLA2G4A/PTPN7/TGFB2/RASGRP3/IL1R1/IL1A/IL1B/TGFBR2/FGFR3/FGF5/EGF/FGF18/PDGFA/FLNC/FGF20/MAP3K8/FAS/NFKB2/FGFR2/CACNA2D4/TNFRSF1A/NFATC4/FOS/GADD45B/CACNA1A/TGFB1/RELB/RRAS/CACNG6/NFATC2/RAC2/PDGFB | 32 |
| HP_ABNORMAL_PULMONARY_INTERSTITIAL_MORPHOLOGY | HP_ABNORMAL_PULMONARY_INTERSTITIAL_MORPHOLOGY | HP_ABNORMAL_PULMONARY_INTERSTITIAL_MORPHOLOGY | 22/1438 | 157/23056 | 0.1401274 | 2.246716 | 4.042623 | 0.0003064 | 0.0020982 | 0.0013489 | PTPN22/CFAP221/COL3A1/CASP10/SP110/SLC34A2/DNAH5/MCIDAS/CCNO/STING1/DSP/HFE/CCN2/CAV1/FAS/SERPINA1/BNC1/ITGA3/TGFB1/KCNN4/HMOX1/RAC2 | 22 |
| GOBP_CELL_RECOGNITION | GOBP_CELL_RECOGNITION | GOBP_CELL_RECOGNITION | 28/1438 | 222/23056 | 0.1261261 | 2.022228 | 3.947185 | 0.0003087 | 0.0021123 | 0.0013579 | NEXN/EPHA4/EPHA3/SPON2/SEMA5A/DOCK2/TNFRSF21/CD36/SEMA3A/ADAM32/EXT1/COLEC10/LY6K/B4GALT1/PAEP/NRP1/MBL2/MYPN/ROBO4/OPCML/MFGE8/CCR7/PECAM1/COLEC12/ATP8B3/CLEC4M/NCAM2/MSN | 28 |
| GOBP_DEFENSE_RESPONSE_TO_BACTERIUM | GOBP_DEFENSE_RESPONSE_TO_BACTERIUM | GOBP_DEFENSE_RESPONSE_TO_BACTERIUM | 40/1438 | 361/23056 | 0.1108033 | 1.776552 | 3.835422 | 0.0003109 | 0.0021269 | 0.0013673 | EPHA2/IL22RA1/GBP2/GBP4/MR1/STAB1/SPON2/JCHAIN/CXCL6/ANXA3/PLAC8/TLR3/IL7R/F2RL1/HLA-E/MICA/IL6/AQP1/CD36/SERPINE1/RARRES2/DEFB107B/GSDMD/IFNE/MBL2/SFTPD/NLRP6/TNFRSF1A/KLRC4-KLRK1/PRKD1/COLEC12/EMILIN2/ELANE/IL27RA/BCL3/C5AR1/DEFB124/WFDC10B/CEBPB/ADAMTS5 | 40 |
| GOBP_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 16/1438 | 97/23056 | 0.1649485 | 2.644681 | 4.186445 | 0.0003150 | 0.0021444 | 0.0013786 | IL1A/IL1B/ITGA6/GDNF/CSF2/TNFAIP3/SERPINE1/NRP1/ITPRIP/TCF7L2/YAP1/IGF1/BMP4/THBS1/ICAM1/HMOX1 | 16 |
| GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TAN_DN | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TAN_DN | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TAN_DN | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | FN1/PLD1/EXT1/NUAK1/CCDC9B | 5 |
| GOBP_FACIAL_NERVE_MORPHOGENESIS | GOBP_FACIAL_NERVE_MORPHOGENESIS | GOBP_FACIAL_NERVE_MORPHOGENESIS | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | NRP2/SEMA3A/NRP1/SIX1/HOXB2 | 5 |
| GOBP_FEVER_GENERATION | GOBP_FEVER_GENERATION | GOBP_FEVER_GENERATION | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | PTGS2/IL1A/IL1B/EDNRB/TNFRSF11A | 5 |
| GOBP_HORMONE_CATABOLIC_PROCESS | GOBP_HORMONE_CATABOLIC_PROCESS | GOBP_HORMONE_CATABOLIC_PROCESS | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | ECE1/SULT1E1/SPP1/DIO2/CYP19A1 | 5 |
| GOBP_MIDGUT_DEVELOPMENT | GOBP_MIDGUT_DEVELOPMENT | GOBP_MIDGUT_DEVELOPMENT | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | CPS1/WNT5A/EDNRB/ALDH1A2/FOXF1 | 5 |
| GOBP_REGULATION_OF_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_REGULATION_OF_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_REGULATION_OF_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | TGFB2/TGFBR2/NOTCH1/NOG/TGFB1 | 5 |
| GOBP_REGULATION_OF_HEART_MORPHOGENESIS | GOBP_REGULATION_OF_HEART_MORPHOGENESIS | GOBP_REGULATION_OF_HEART_MORPHOGENESIS | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | WNT5A/DKK1/BMP4/BMP2/GATA5 | 5 |
| GOCC_PEPTIDASE_INHIBITOR_COMPLEX | GOCC_PEPTIDASE_INHIBITOR_COMPLEX | GOCC_PEPTIDASE_INHIBITOR_COMPLEX | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | SERPINE1/PLAT/PLAU/CASP1/CARD16 | 5 |
| GOMF_PLATELET_DERIVED_GROWTH_FACTOR_BINDING | GOMF_PLATELET_DERIVED_GROWTH_FACTOR_BINDING | GOMF_PLATELET_DERIVED_GROWTH_FACTOR_BINDING | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | COL3A1/PDGFA/COL5A1/COL1A1/PDGFB | 5 |
| HP_ARTERIOVENOUS_FISTULA | HP_ARTERIOVENOUS_FISTULA | HP_ARTERIOVENOUS_FISTULA | 5/1438 | 11/23056 | 0.4545455 | 7.287900 | 5.379821 | 0.0003152 | 0.0021444 | 0.0013786 | COL3A1/COL5A2/EPHB4/COL5A1/COL1A1 | 5 |
| DOUGLAS_BMI1_TARGETS_DN | DOUGLAS_BMI1_TARGETS_DN | DOUGLAS_BMI1_TARGETS_DN | 36/1438 | 314/23056 | 0.1146497 | 1.838222 | 3.857125 | 0.0003180 | 0.0021623 | 0.0013901 | TNFRSF9/MR1/TMEM63A/LRP1B/COL3A1/COL5A2/CASP8/SP100/RARB/PLSCR4/LPP/IL1RAP/RBM47/EGF/SLC7A11/TMEM144/DDX60L/IL7R/PSMB9/TNFAIP3/SEMA3A/CLU/FZD6/NFKB2/BIRC3/GPRC5A/STAT6/ACSS3/LCP1/IRF9/IL32/SLFN5/DHX58/IFI35/ICAM1/MLC1 | 36 |
| GOBP_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION | GOBP_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION | GOBP_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION | 32/1438 | 268/23056 | 0.1194030 | 1.914433 | 3.883476 | 0.0003265 | 0.0022188 | 0.0014264 | S1PR1/RHOC/S100A10/LMOD1/CAPG/PHLDB2/SLIT2/SEMA5A/F2RL1/ARHGAP18/CCN2/SCIN/CCL26/MET/LMOD2/ARHGEF5/GSN/NRP1/SYNPO2L/APOA1/EPS8/NCKAP1L/CGNL1/TPM1/COTL1/CSF3/CCR7/GMFG/CDC42EP5/SDC4/CDC42EP1/TENM1 | 32 |
| GOBP_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 17/1438 | 107/23056 | 0.1588785 | 2.547359 | 4.137666 | 0.0003283 | 0.0022257 | 0.0014308 | S100A13/SPON2/CXCL6/ANXA3/F2RL1/HLA-E/IL6/DDX58/NLRP6/IL4R/LAT/FOXF1/MILR1/ELANE/C3/HMOX1/RAC2 | 17 |
| GOMF_PHOSPHATIDYLINOSITOL_BISPHOSPHATE_BINDING | GOMF_PHOSPHATIDYLINOSITOL_BISPHOSPHATE_BINDING | GOMF_PHOSPHATIDYLINOSITOL_BISPHOSPHATE_BINDING | 17/1438 | 107/23056 | 0.1588785 | 2.547359 | 4.137666 | 0.0003283 | 0.0022257 | 0.0014308 | LDLRAP1/CAPG/SCIN/GSDMD/GSN/ANXA8/SYTL2/TPCN1/PLEK2/ANXA2/GRAMD2A/ADAP2/WIPI1/KCNJ2/SDCBP2/JPH2/FRMPD4 | 17 |
| HP_HYPOTENSION | HP_HYPOTENSION | HP_HYPOTENSION | 17/1438 | 107/23056 | 0.1588785 | 2.547359 | 4.137666 | 0.0003283 | 0.0022257 | 0.0014308 | CFH/AGT/KYNU/COL5A2/CFI/SIM1/CAV1/TNFSF15/GSN/COL5A1/NFKB2/SAA1/SCNN1A/SERPINA6/COL1A1/IL12RB1/RUNX1 | 17 |
| PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | 17/1438 | 107/23056 | 0.1588785 | 2.547359 | 4.137666 | 0.0003283 | 0.0022257 | 0.0014308 | TINAGL1/COL3A1/SEMA3B/WNT5A/FAT4/NPR3/CYP39A1/PERP/LOXL2/MYBL1/PCSK5/ZCCHC24/PPP1R3C/FGFR2/HMGA2/TPM1/SLC14A1 | 17 |
| ZHU_CMV_ALL_UP | ZHU_CMV_ALL_UP | ZHU_CMV_ALL_UP | 17/1438 | 107/23056 | 0.1588785 | 2.547359 | 4.137666 | 0.0003283 | 0.0022257 | 0.0014308 | GBP1/PTGS2/PLA2G4A/SP100/IL7R/HLA-E/PSMB8/TNFAIP3/IL6/IDO1/ITGA8/LATS2/NFKBIA/CCL5/IL11/MX2/MX1 | 17 |
| GOBP_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | GOBP_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | GOBP_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION | 41/1438 | 374/23056 | 0.1096257 | 1.757670 | 3.810039 | 0.0003290 | 0.0022296 | 0.0014333 | S1PR1/RHOC/S100A10/LMOD1/BMP10/CAPG/PHLDB2/SLIT2/SEMA5A/F2RL1/EDN1/ARHGAP18/CCN2/SCIN/CCL26/MET/LMOD2/ARHGEF5/CLU/GSN/NRP1/SYNPO2L/EFEMP2/CRYAB/APOA1/EPS8/NCKAP1L/NAV3/CGNL1/TPM1/MYLK3/COTL1/CSF3/CCR7/GMFG/APOE/CDC42EP5/SDC4/CDC42EP1/MID1/TENM1 | 41 |
| HP_CONGENITAL_DIAPHRAGMATIC_HERNIA | HP_CONGENITAL_DIAPHRAGMATIC_HERNIA | HP_CONGENITAL_DIAPHRAGMATIC_HERNIA | 15/1438 | 88/23056 | 0.1704545 | 2.732962 | 4.200714 | 0.0003330 | 0.0022543 | 0.0014492 | RARB/CD96/GLI3/SHH/ZFPM2/RSPO2/WT1/EFEMP2/ZIC2/DACT1/FBLN5/MAF/GATA6/MN1/GPC4 | 15 |
| MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP | 15/1438 | 88/23056 | 0.1704545 | 2.732962 | 4.200714 | 0.0003330 | 0.0022543 | 0.0014492 | MITF/CXCL1/DSP/DDR1/SASH1/EPHB4/EPHB6/B4GALT1/C3AR1/STYK1/PYGL/MRC2/MBP/BIRC7/PDGFB | 15 |
| GOBP_MONOCARBOXYLIC_ACID_TRANSPORT | GOBP_MONOCARBOXYLIC_ACID_TRANSPORT | GOBP_MONOCARBOXYLIC_ACID_TRANSPORT | 18/1438 | 117/23056 | 0.1538462 | 2.466674 | 4.101979 | 0.0003340 | 0.0022590 | 0.0014522 | PLA2G4A/IL1A/IL1B/SLCO2A1/ABCG2/EDN1/CD36/ANXA1/SLC16A12/SLC5A12/SLCO2B1/SLC6A13/SLC10A2/CES1/ABCC3/SLC16A5/SLC16A3/TNFRSF11A | 18 |
| HP_SOFT_TISSUE_SARCOMA | HP_SOFT_TISSUE_SARCOMA | HP_SOFT_TISSUE_SARCOMA | 18/1438 | 117/23056 | 0.1538462 | 2.466674 | 4.101979 | 0.0003340 | 0.0022590 | 0.0014522 | PTCH2/KCNN3/CASP10/FGFR3/VEGFC/FAM20C/PDGFRL/FAS/SLC22A18/PTPRJ/FOXO1/KRT17/COL1A1/PDGFB/SSX1/SSX2/COL4A6/COL4A5 | 18 |
| HP_ABNORMALITY_OF_THE_RIBS | HP_ABNORMALITY_OF_THE_RIBS | HP_ABNORMALITY_OF_THE_RIBS | 34/1438 | 292/23056 | 0.1164384 | 1.866900 | 3.844949 | 0.0003461 | 0.0023395 | 0.0015040 | MMP23B/HSPG2/PTCH2/FGFRL1/FGFR3/NKX3-2/RUNX2/TENT5A/BMPER/GLI3/SHH/GDF6/RSPO2/EXT1/GAS1/FGFR2/CREB3L1/SERPINH1/ZIC2/DACT1/FBN1/SALL1/MAF/FOXF1/MEOX1/COL1A1/NOG/SOX9/GATA6/TNFRSF11A/BMP2/ARSL/GPC4/BGN | 34 |
| HP_POSITIONAL_FOOT_DEFORMITY | HP_POSITIONAL_FOOT_DEFORMITY | HP_POSITIONAL_FOOT_DEFORMITY | 42/1438 | 387/23056 | 0.1085271 | 1.740057 | 3.786679 | 0.0003464 | 0.0023405 | 0.0015046 | HSPG2/TBX15/TGFB2/KYNU/COL3A1/COL5A2/DES/COL6A3/TWIST2/TGFBR2/LAMB2/CD96/FGFRL1/DOK7/FAT4/ARSI/RREB1/COL12A1/ADGRG6/BMPER/GLI3/SAMD9/SHH/RSPO2/TRPS1/EXT1/TPM2/COL5A1/NOTCH1/ITGA8/MYPN/FGFR2/ITGA7/ZIC2/FBN1/SMAD6/MYH8/COL1A1/SOX9/PIEZO2/COL6A2/GPC4 | 42 |
| BIOCARTA_ALK_PATHWAY | BIOCARTA_ALK_PATHWAY | BIOCARTA_ALK_PATHWAY | 9/1438 | 37/23056 | 0.2432432 | 3.900011 | 4.553146 | 0.0003524 | 0.0023737 | 0.0015260 | TGFB2/BMP10/TGFBR2/FZD1/BMP4/SMAD6/NOG/TGFB1/BMP2 | 9 |
| GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN | 9/1438 | 37/23056 | 0.2432432 | 3.900011 | 4.553146 | 0.0003524 | 0.0023737 | 0.0015260 | CD53/TFPI/TWIST2/VEGFC/RAET1E/TSPAN12/AKR1B10/NNMT/SERPINB2 | 9 |
| GOBP_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY | 9/1438 | 37/23056 | 0.2432432 | 3.900011 | 4.553146 | 0.0003524 | 0.0023737 | 0.0015260 | FGFR3/TEK/FLT3/FLT1/PRKD1/TNFAIP8L3/CCR7/TGFB1/PDGFB | 9 |
| GOBP_REGULATION_OF_KERATINOCYTE_PROLIFERATION | GOBP_REGULATION_OF_KERATINOCYTE_PROLIFERATION | GOBP_REGULATION_OF_KERATINOCYTE_PROLIFERATION | 9/1438 | 37/23056 | 0.2432432 | 3.900011 | 4.553146 | 0.0003524 | 0.0023737 | 0.0015260 | CD109/PTPRK/HAS2/EPPK1/FGFR2/YAP1/PRKD1/ZFP36L1/ZFP36 | 9 |
| HP_ABNORMAL_HEART_SOUND | HP_ABNORMAL_HEART_SOUND | HP_ABNORMAL_HEART_SOUND | 9/1438 | 37/23056 | 0.2432432 | 3.900011 | 4.553146 | 0.0003524 | 0.0023737 | 0.0015260 | LDLRAP1/GJA1/CITED2/NOTCH1/ACTC1/FBN1/SMAD6/GATA6/GATA5 | 9 |
| WP_NEOVASCULARISATION_PROCESSES | WP_NEOVASCULARISATION_PROCESSES | WP_NEOVASCULARISATION_PROCESSES | 9/1438 | 37/23056 | 0.2432432 | 3.900011 | 4.553146 | 0.0003524 | 0.0023737 | 0.0015260 | TGFB2/KDR/EPHB4/ANGPT1/NOTCH1/NFKB2/TGFB1/RELB/PDGFB | 9 |
| GOBP_CHEMOKINE_PRODUCTION | GOBP_CHEMOKINE_PRODUCTION | GOBP_CHEMOKINE_PRODUCTION | 16/1438 | 98/23056 | 0.1632653 | 2.617695 | 4.139013 | 0.0003550 | 0.0023878 | 0.0015351 | EPHA2/MCOLN2/IL1B/WNT5A/CXCL6/TLR3/F2RL1/TSLP/IL6/KLF4/IL4R/MBP/ELANE/SIRPA/DEFB124/HMOX1 | 16 |
| GOBP_POSITIVE_REGULATION_OF_ENDOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_ENDOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_ENDOCYTOSIS | 16/1438 | 98/23056 | 0.1632653 | 2.617695 | 4.139013 | 0.0003550 | 0.0023878 | 0.0015351 | LDLRAP1/WNT5A/EGF/DAB2/ITGA2/F2RL1/HFE/CD36/SERPINE1/CLU/ANGPT1/NCKAP1L/ANXA2/C3/AXL/APOE | 16 |
| GOBP_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 16/1438 | 98/23056 | 0.1632653 | 2.617695 | 4.139013 | 0.0003550 | 0.0023878 | 0.0015351 | BMP10/CYP26B1/EDN1/RBM24/SHH/NOTCH1/DKK1/BHLHE41/IGF1/MMP14/BMP4/MYLK3/PIEZO1/MYOCD/TGFB1/BMP2 | 16 |
| GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 24/1438 | 180/23056 | 0.1333333 | 2.137784 | 3.952394 | 0.0003563 | 0.0023952 | 0.0015398 | GFI1/PTPN22/CTSS/RAB7B/NMI/IRAK2/TNIP3/DDX60/TLR3/F2RL1/TNFAIP3/CD36/CAV1/DDX58/MBL2/NLRP6/SLC15A3/BIRC3/OASL/NFKBIA/RNF135/DHX58/IFI35/COLEC12 | 24 |
| GOBP_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER | GOBP_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER | GOBP_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER | 11/1438 | 53/23056 | 0.2075472 | 3.327683 | 4.375460 | 0.0003589 | 0.0024104 | 0.0015496 | IL1B/CLDN1/F2RL1/S1PR3/VCL/ROBO4/TNFRSF1A/EDNRB/PECAM1/ICAM1/MSN | 11 |
| HP_SPINAL_RIGIDITY | HP_SPINAL_RIGIDITY | HP_SPINAL_RIGIDITY | 11/1438 | 53/23056 | 0.2075472 | 3.327683 | 4.375460 | 0.0003589 | 0.0024104 | 0.0015496 | AGRN/HSPG2/DES/COL6A3/COL12A1/TPM2/MYPN/COL13A1/BAG3/CAVIN1/COL6A2 | 11 |
| HP_ABNORMAL_FEMALE_REPRODUCTIVE_SYSTEM_PHYSIOLOGY | HP_ABNORMAL_FEMALE_REPRODUCTIVE_SYSTEM_PHYSIOLOGY | HP_ABNORMAL_FEMALE_REPRODUCTIVE_SYSTEM_PHYSIOLOGY | 36/1438 | 316/23056 | 0.1139241 | 1.826588 | 3.815851 | 0.0003591 | 0.0024107 | 0.0015498 | HJV/CCDC141/NABP1/CASP10/IL17RC/PPARG/FOXL2/PCSK1/HFE/PSMB8/SIM1/CCN2/SEMA3A/SERPINE1/CAV1/PODXL/PLAG1/ZFPM2/ITGA8/PLAU/PAPSS2/FAS/WT1/VWF/HMGA2/BMP4/FOS/CYP19A1/BNC1/CAVIN1/SOX9/AXL/BMP2/RIN2/MYH9/PDGFB | 36 |
| HP_THORACIC_HYPOPLASIA | HP_THORACIC_HYPOPLASIA | HP_THORACIC_HYPOPLASIA | 20/1438 | 138/23056 | 0.1449275 | 2.323678 | 4.022424 | 0.0003615 | 0.0024247 | 0.0015587 | AGRN/HSPG2/ACTG2/KYNU/FGFR3/ADAMTS3/FAT4/RUNX2/TENT5A/FAM20C/BMPER/TPM2/MYPN/FGFR2/SERPINH1/GLI1/FBN1/ITGA3/COL1A1/SOX9 | 20 |
| RIEGE_DELTANP63_DIRECT_TARGETS_UP | RIEGE_DELTANP63_DIRECT_TARGETS_UP | RIEGE_DELTANP63_DIRECT_TARGETS_UP | 20/1438 | 138/23056 | 0.1449275 | 2.323678 | 4.022424 | 0.0003615 | 0.0024247 | 0.0015587 | S100A2/IFI16/IL1B/ITGA6/TMEM40/RASSF6/MYO10/MMRN2/CD44/FOSL1/RAB38/YAP1/ARHGDIB/HMGA2/MMP14/EHD4/IL4R/TGFB1/PROCR/CARD10 | 20 |
| GOBP_DECIDUALIZATION | GOBP_DECIDUALIZATION | GOBP_DECIDUALIZATION | 7/1438 | 23/23056 | 0.3043478 | 4.879724 | 4.801133 | 0.0003655 | 0.0024443 | 0.0015713 | PTGS2/SPP1/CITED2/PTN/STC1/LIF/NDP | 7 |
| GOBP_GLOMERULAR_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_GLOMERULAR_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_GLOMERULAR_EPITHELIAL_CELL_DIFFERENTIATION | 7/1438 | 23/23056 | 0.3043478 | 4.879724 | 4.801133 | 0.0003655 | 0.0024443 | 0.0015713 | LAMB2/PODXL/EXT1/WT1/EDNRB/BMP4/MYO1E | 7 |
| GOBP_OVULATION | GOBP_OVULATION | GOBP_OVULATION | 7/1438 | 23/23056 | 0.3043478 | 4.879724 | 4.801133 | 0.0003655 | 0.0024443 | 0.0015713 | PTGS2/EREG/INHBA/PLAT/PGR/IL4R/MMP2 | 7 |
| HP_ABNORMAL_PERISTALSIS | HP_ABNORMAL_PERISTALSIS | HP_ABNORMAL_PERISTALSIS | 7/1438 | 23/23056 | 0.3043478 | 4.879724 | 4.801133 | 0.0003655 | 0.0024443 | 0.0015713 | LMOD1/ACTG2/MYLK/SAMD9/MYL9/COL4A6/COL4A5 | 7 |
| HP_DECREASED_URINE_OUTPUT | HP_DECREASED_URINE_OUTPUT | HP_DECREASED_URINE_OUTPUT | 7/1438 | 23/23056 | 0.3043478 | 4.879724 | 4.801133 | 0.0003655 | 0.0024443 | 0.0015713 | CFH/AGT/CFI/CCN2/CAV1/C3/THBD | 7 |
| VERNELL_RETINOBLASTOMA_PATHWAY_DN | VERNELL_RETINOBLASTOMA_PATHWAY_DN | VERNELL_RETINOBLASTOMA_PATHWAY_DN | 7/1438 | 23/23056 | 0.3043478 | 4.879724 | 4.801133 | 0.0003655 | 0.0024443 | 0.0015713 | CCN2/CITED2/ITGB8/SERPINE1/CPA4/GPRC5A/LACTB | 7 |
| HP_PERIORBITAL_EDEMA | HP_PERIORBITAL_EDEMA | HP_PERIORBITAL_EDEMA | 17/1438 | 108/23056 | 0.1574074 | 2.523773 | 4.093680 | 0.0003674 | 0.0024542 | 0.0015777 | PTPN22/COL5A2/ARHGAP24/ADAMTS2/PSMB9/TMEM270/GSN/CRB2/COL5A1/WT1/TNFRSF1A/MYO1E/PIEZO1/COL1A1/RIN2/APOL1/TBC1D8B | 17 |
| HP_SYNCOPE | HP_SYNCOPE | HP_SYNCOPE | 17/1438 | 108/23056 | 0.1574074 | 2.523773 | 4.093680 | 0.0003674 | 0.0024542 | 0.0015777 | TNNC1/TECRL/DSP/MOG/TRDN/CITED2/SEMA3A/FLNC/MYPN/SCNN1A/ACTC1/HCN4/JUP/KCNJ2/GATA6/SCN1B/PDGFB | 17 |
| GOBP_CELLULAR_RESPONSE_TO_PEPTIDE | GOBP_CELLULAR_RESPONSE_TO_PEPTIDE | GOBP_CELLULAR_RESPONSE_TO_PEPTIDE | 40/1438 | 364/23056 | 0.1098901 | 1.761910 | 3.778959 | 0.0003681 | 0.0024576 | 0.0015799 | C1QTNF12/ERRFI1/RPE65/VCAM1/PTPN22/AGT/IL1B/ITGA4/CPS1/EPHA4/PPARG/CRHBP/MZB1/ADRB2/EDN1/GJA1/CD36/PDK4/CAV2/CAV1/RARRES2/PLAT/ADCY8/PTPRE/CASP4/TNS2/STAT6/IGF1/FOXO1/ZFP36L1/FBN1/GLP2R/GRB7/SOCS3/ICAM1/CACNA1A/KLF2/GDF15/PRNP/PNPLA3 | 40 |
| GOBP_MYOBLAST_FUSION | GOBP_MYOBLAST_FUSION | GOBP_MYOBLAST_FUSION | 10/1438 | 45/23056 | 0.2222222 | 3.562973 | 4.438506 | 0.0003693 | 0.0024584 | 0.0015804 | CD53/MYOF/ADAMTS15/IL4R/TNFSF14/GDF15/EHD2/NFATC2/ADAMTS5/MYH9 | 10 |
| GOBP_POSITIVE_REGULATION_OF_MIRNA_TRANSCRIPTION | GOBP_POSITIVE_REGULATION_OF_MIRNA_TRANSCRIPTION | GOBP_POSITIVE_REGULATION_OF_MIRNA_TRANSCRIPTION | 10/1438 | 45/23056 | 0.2222222 | 3.562973 | 4.438506 | 0.0003693 | 0.0024584 | 0.0015804 | TGFB2/PPARG/KLF4/WT1/FOSL1/FOS/SMAD6/TGFB1/BMP2/PDGFB | 10 |
| GOBP_POSITIVE_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | 10/1438 | 45/23056 | 0.2222222 | 3.562973 | 4.438506 | 0.0003693 | 0.0024584 | 0.0015804 | TGFA/EPGN/EREG/BTC/EGF/HBEGF/ADRB2/EDN1/HFE/NRP1 | 10 |
| PID_NFAT_TFPATHWAY | PID_NFAT_TFPATHWAY | PID_NFAT_TFPATHWAY | 10/1438 | 45/23056 | 0.2222222 | 3.562973 | 4.438506 | 0.0003693 | 0.0024584 | 0.0015804 | GBP3/PTGS2/PPARG/CXCL8/CSF2/PTPRK/FOSL1/FOS/MAF/NFATC2 | 10 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN | 10/1438 | 45/23056 | 0.2222222 | 3.562973 | 4.438506 | 0.0003693 | 0.0024584 | 0.0015804 | PTPRC/IRAK2/TM4SF1/PDGFA/AQP1/INHBA/SERPINE1/TRAF1/ZFP36/HMOX1 | 10 |
| WP_NEPHROTIC_SYNDROME | WP_NEPHROTIC_SYNDROME | WP_NEPHROTIC_SYNDROME | 10/1438 | 45/23056 | 0.2222222 | 3.562973 | 4.438506 | 0.0003693 | 0.0024584 | 0.0015804 | LAMB2/ARHGAP24/PODXL/WT1/MYO1E/ITGA3/ITGB4/APOL1/MYH9/COL4A5 | 10 |
| HP_ABNORMALITY_OF_THE_PHALANGES_OF_THE_TOES | HP_ABNORMALITY_OF_THE_PHALANGES_OF_THE_TOES | HP_ABNORMALITY_OF_THE_PHALANGES_OF_THE_TOES | 18/1438 | 118/23056 | 0.1525424 | 2.445770 | 4.060847 | 0.0003716 | 0.0024728 | 0.0015897 | KCNN3/COL3A1/COL6A3/SLCO2A1/FGFR3/COL12A1/GLI3/FGFR2/DACT1/SALL1/NOG/SOX9/RHBDF2/SCN1B/BMP2/COL6A2/ARSL/GPC4 | 18 |
| GOBP_REGULATION_OF_CELL_MORPHOGENESIS | GOBP_REGULATION_OF_CELL_MORPHOGENESIS | GOBP_REGULATION_OF_CELL_MORPHOGENESIS | 35/1438 | 305/23056 | 0.1147541 | 1.839896 | 3.808285 | 0.0003758 | 0.0024998 | 0.0016070 | FBLIM1/GBP1/RHOC/S100A10/FN1/EPHA4/WNT5A/OSTN/KDR/MYO10/DAB2/SPARC/RREB1/ARHGAP18/HAS2/ANXA1/NRP1/DNMBP/CD44/FZD4/APOA1/BCL9L/EPS8/RND1/ITGA7/GRIP1/EPB42/TPM1/FMNL1/WTIP/CDC42EP5/MYH9/RAC2/CDC42EP1/MSN | 35 |
| GOBP_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 50/1438 | 487/23056 | 0.1026694 | 1.646138 | 3.716957 | 0.0003774 | 0.0025090 | 0.0016130 | RHOC/S100A10/LMOD1/BMP10/TGFA/CAPG/IL1A/IL1B/WNT5A/KDR/EPGN/EREG/BTC/EGF/SEMA5A/F2RL1/CSF2/ADRB2/EDN1/CCN2/SCIN/CCL26/MET/LMOD2/STRA8/ARHGEF5/TEK/ANXA1/GSN/NRP1/SYNPO2L/APOA1/NCKAP1L/NAV3/IGF1/LCP1/BMF/ANXA2/TPM1/MYLK3/CSF3/CCR7/HAP1/WIPI1/CDC42EP5/SDC4/CDC42EP1/PDGFB/MSN/TENM1 | 50 |
| GOBP_RESPONSE_TO_CAMP | GOBP_RESPONSE_TO_CAMP | GOBP_RESPONSE_TO_CAMP | 15/1438 | 89/23056 | 0.1685393 | 2.702255 | 4.149748 | 0.0003778 | 0.0025104 | 0.0016138 | CPS1/CRHBP/AHR/AQP1/STC1/PLAT/WT1/FOSL1/WNT10B/ZFP36L1/FOS/HCN4/COL1A1/GATA6/THBD | 15 |
| HELLER_HDAC_TARGETS_UP | HELLER_HDAC_TARGETS_UP | HELLER_HDAC_TARGETS_UP | 36/1438 | 317/23056 | 0.1135647 | 1.820825 | 3.795325 | 0.0003814 | 0.0025254 | 0.0016235 | AGRN/CFH/DLX2/ITGA6/FN1/BCL6/HES1/PLK2/GMPR/FAM20C/MICALL2/TRIP6/TSPAN12/PDGFRL/GSN/AKR1C3/VCL/ZCCHC24/MYRF/EHBP1L1/BIRC3/H2AJ/ITGA7/CYP46A1/MT2A/MT1X/COTL1/JUP/LLGL2/SLC16A3/KLF2/BLVRB/RRAS/SDC4/SAT1/IL13RA1 | 36 |
| HP_ABNORMAL_BLOOD_ION_CONCENTRATION | HP_ABNORMAL_BLOOD_ION_CONCENTRATION | HP_ABNORMAL_BLOOD_ION_CONCENTRATION | 36/1438 | 317/23056 | 0.1135647 | 1.820825 | 3.795325 | 0.0003814 | 0.0025254 | 0.0016235 | HJV/LAMC2/LAMB3/GALNT3/COL3A1/COL7A1/CLDN16/ADAMTS3/EGF/FAT4/TLR3/RREB1/HFE/TRDN/FAM20C/TMEM270/SAMD9/CAV1/ATP6V0A4/SHH/TNFRSF11B/TRPM6/NFKB2/MMP1/SCNN1A/STAT6/ZIC2/SLC7A7/CA12/PIEZO1/KCNJ2/TNFRSF11A/PLVAP/KCNN4/BMP2/CYP24A1 | 36 |
| GOBP_AMINE_CATABOLIC_PROCESS | GOBP_AMINE_CATABOLIC_PROCESS | GOBP_AMINE_CATABOLIC_PROCESS | 8/1438 | 30/23056 | 0.2666667 | 4.275568 | 4.630120 | 0.0003815 | 0.0025254 | 0.0016235 | ATP2B4/HNMT/KYNU/TDO2/MOXD1/IDO1/IL4I1/SAT1 | 8 |
| GOBP_MYELOID_LEUKOCYTE_CYTOKINE_PRODUCTION | GOBP_MYELOID_LEUKOCYTE_CYTOKINE_PRODUCTION | GOBP_MYELOID_LEUKOCYTE_CYTOKINE_PRODUCTION | 8/1438 | 30/23056 | 0.2666667 | 4.275568 | 4.630120 | 0.0003815 | 0.0025254 | 0.0016235 | TGFB2/WNT5A/BCL6/SPON2/CD36/DDX58/TGFB1/HMOX1 | 8 |
| GOBP_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | GOBP_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | GOBP_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION | 8/1438 | 30/23056 | 0.2666667 | 4.275568 | 4.630120 | 0.0003815 | 0.0025254 | 0.0016235 | CD53/GCM1/ADAM9/IL4R/TNFSF14/GDF15/EHD2/NFATC2 | 8 |
| GOMF_WNT_PROTEIN_BINDING | GOMF_WNT_PROTEIN_BINDING | GOMF_WNT_PROTEIN_BINDING | 8/1438 | 30/23056 | 0.2666667 | 4.275568 | 4.630120 | 0.0003815 | 0.0025254 | 0.0016235 | TRABD2B/TRABD2A/FZD1/FZD6/CTHRC1/FZD8/FZD4/APCDD1L | 8 |
| HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN | HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN | HOLLERN_SOLID_NODULAR_BREAST_TUMOR_DN | 8/1438 | 30/23056 | 0.2666667 | 4.275568 | 4.630120 | 0.0003815 | 0.0025254 | 0.0016235 | NID1/SPARC/GJA1/AQP1/GLI3/HAS2/ICAM1/BMP2 | 8 |
| HP_VASCULAR_CALCIFICATION | HP_VASCULAR_CALCIFICATION | HP_VASCULAR_CALCIFICATION | 8/1438 | 30/23056 | 0.2666667 | 4.275568 | 4.630120 | 0.0003815 | 0.0025254 | 0.0016235 | LDLRAP1/GALNT3/SLC34A2/NT5E/NOTCH1/SMAD6/GATA5/PDGFB | 8 |
| SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | 31/1438 | 259/23056 | 0.1196911 | 1.919053 | 3.836241 | 0.0003849 | 0.0025464 | 0.0016370 | FRRS1/IKBKE/CD34/TGFB2/SRD5A2/COL3A1/ACKR3/CLDN1/HES1/SPON2/RAI14/FST/ITPR3/NEK6/PLAU/PTPRE/PRSS23/YAP1/CASP1/KRT18/LOXL1/MFGE8/RHBDF1/OSGIN1/ITGA3/SCN1B/LYPD3/SIRPA/TGM2/COL4A5/HAUS7 | 31 |
| GOBP_B_CELL_ACTIVATION | GOBP_B_CELL_ACTIVATION | GOBP_B_CELL_ACTIVATION | 37/1438 | 329/23056 | 0.1124620 | 1.803146 | 3.784214 | 0.0003854 | 0.0025483 | 0.0016382 | TNFRSF4/VCAM1/PTPRC/LAX1/ITGA4/CASP8/BCL6/LEF1/IL7R/MZB1/TNFRSF21/TNFAIP3/AHR/IL6/SKAP2/INHBA/ST3GAL1/IFNE/HHEX/PTPRJ/NCKAP1L/STAT6/FLT3/TNFSF13B/MMP14/ZFP36L1/CD70/IL27RA/CD22/TGFB1/BCL3/IL4I1/IL11/NFATC2/ICOSLG/LGALS1/ITM2A | 37 |
| GOMF_ENZYME_INHIBITOR_ACTIVITY | GOMF_ENZYME_INHIBITOR_ACTIVITY | GOMF_ENZYME_INHIBITOR_ACTIVITY | 42/1438 | 389/23056 | 0.1079692 | 1.731110 | 3.750723 | 0.0003858 | 0.0025500 | 0.0016393 | ATP2B4/AGT/CRIM1/PPP1R1C/TFPI/SERPINE2/COL6A3/COL7A1/ITIH3/SLIT2/ANXA3/IQGAP2/SH3RF2/SERPINB1/CD109/SERPINE1/PTN/ANXA1/CRB2/NOTCH1/MYOZ1/ITPRIP/SERPINH1/BIRC3/CARD16/APOC3/SERPINE3/SERPINA10/SERPINA6/SERPINA1/ANXA2/SOCS3/SERPINB7/SERPINB2/SERPINB8/TNFSF14/C3/GMFG/PRNP/WFDC10B/BIRC7/ELFN2 | 42 |
| GOBP_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | GOBP_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | GOBP_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | 12/1438 | 62/23056 | 0.1935484 | 3.103235 | 4.276915 | 0.0003892 | 0.0025697 | 0.0016520 | PTPN22/IL1B/IRAK2/BMP6/TNFAIP3/SASH1/CD36/TRIM5/CARD16/NFKBIA/CCL5/TGFB1 | 12 |
| REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | 12/1438 | 62/23056 | 0.1935484 | 3.103235 | 4.276915 | 0.0003892 | 0.0025697 | 0.0016520 | GALNT5/GALNT3/GALNT15/MUC13/GALNTL6/GALNT10/GALNT17/ST3GAL1/GALNT18/GALNT9/MUC16/B3GNT3 | 12 |
| HAMAI_APOPTOSIS_VIA_TRAIL_DN | HAMAI_APOPTOSIS_VIA_TRAIL_DN | HAMAI_APOPTOSIS_VIA_TRAIL_DN | 26/1438 | 203/23056 | 0.1280788 | 2.053536 | 3.888483 | 0.0003917 | 0.0025855 | 0.0016621 | FOXD2/KYNU/TWIST2/SPON2/SERPINB1/IFITM2/PHLDA2/CCKBR/SLC15A3/SERPINH1/KCNA5/KRT18/FOXB1/IL4R/SLC16A5/SIGLEC15/FSTL3/ICAM1/KLF2/GDF15/FXYD5/BCL3/APOE/KLK6/FOXS1/MAGEA1 | 26 |
| GOBP_REGULATION_OF_STEROL_TRANSPORT | GOBP_REGULATION_OF_STEROL_TRANSPORT | GOBP_REGULATION_OF_STEROL_TRANSPORT | 14/1438 | 80/23056 | 0.1750000 | 2.805841 | 4.172935 | 0.0003938 | 0.0025956 | 0.0016686 | LDLRAP1/PPARG/EGF/CAV1/SHH/APOC3/APOA1/NFKBIA/ANXA2/CES1/CETP/ABCA8/LIPG/APOE | 14 |
| LIAN_LIPA_TARGETS_6M | LIAN_LIPA_TARGETS_6M | LIAN_LIPA_TARGETS_6M | 14/1438 | 80/23056 | 0.1750000 | 2.805841 | 4.172935 | 0.0003938 | 0.0025956 | 0.0016686 | FCGR2A/RAB7B/CXCL3/PLA2G7/UTRN/GPNMB/MSR1/PAPPA/SLC15A3/C3AR1/TNFAIP2/CD68/GDF15/HMOX1 | 14 |
| HP_ABNORMALITY_OF_THE_UPPER_RESPIRATORY_TRACT | HP_ABNORMALITY_OF_THE_UPPER_RESPIRATORY_TRACT | HP_ABNORMALITY_OF_THE_UPPER_RESPIRATORY_TRACT | 45/1438 | 426/23056 | 0.1056338 | 1.693667 | 3.727072 | 0.0003938 | 0.0025956 | 0.0016686 | HSPG2/FUCA1/GFI1/PTPN22/FCGR2A/PRRX1/LAMC2/LAMB3/CFAP221/COL5A2/EPHA4/FGFR3/CFI/DNAH5/IL7R/MCIDAS/CCNO/RREB1/EDN1/PSMB8/PSMB9/TAPBP/RUNX2/COL12A1/GJA1/GLI3/PON3/SHH/RSPO2/COL5A1/NFKB2/FGFR2/TNFRSF1A/SCNN1A/GRIP1/FREM2/IL21R/KCNJ2/SOX9/ELANE/TGFB1/RAC2/ARSL/MID1/SRPX2 | 45 |
| BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | BOWIE_RESPONSE_TO_EXTRACELLULAR_MATRIX | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | IFI16/PSMB8/PSMB9/PSMB10/IFI35/MX1 | 6 |
| GOBP_EPITHELIAL_CELL_CELL_ADHESION | GOBP_EPITHELIAL_CELL_CELL_ADHESION | GOBP_EPITHELIAL_CELL_CELL_ADHESION | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | ITGB5/DSP/VCL/KIFC3/JUP/SERPINB8 | 6 |
| GOBP_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | ZC3H12A/ATP2B4/CD34/CAV1/SIRPA/PTGIS | 6 |
| HP_ANTIPHOSPHOLIPID_ANTIBODY_POSITIVITY | HP_ANTIPHOSPHOLIPID_ANTIBODY_POSITIVITY | HP_ANTIPHOSPHOLIPID_ANTIBODY_POSITIVITY | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | PTPN22/FCGR2A/CASP10/SPP1/STING1/FAS | 6 |
| HP_MICROGLOSSIA | HP_MICROGLOSSIA | HP_MICROGLOSSIA | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | TBX15/ECM1/PRRX1/EDN1/GLI3/BMP4 | 6 |
| JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN | JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN | JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | FN1/VEGFC/THBS2/LUM/LOXL1/MMP2 | 6 |
| REACTOME_GAB1_SIGNALOSOME | REACTOME_GAB1_SIGNALOSOME | REACTOME_GAB1_SIGNALOSOME | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | TGFA/EPGN/EREG/BTC/EGF/HBEGF | 6 |
| WP_METABOLIC_PATHWAY_OF_LDL_HDL_AND_TG_INCLUDING_DISEASES | WP_METABOLIC_PATHWAY_OF_LDL_HDL_AND_TG_INCLUDING_DISEASES | WP_METABOLIC_PATHWAY_OF_LDL_HDL_AND_TG_INCLUDING_DISEASES | 6/1438 | 17/23056 | 0.3529412 | 5.658840 | 4.955925 | 0.0003966 | 0.0026037 | 0.0016738 | LDLRAP1/APOA1/ANXA2/CETP/LIPG/APOE | 6 |
| HP_HYDROURETER | HP_HYDROURETER | HP_HYDROURETER | 13/1438 | 71/23056 | 0.1830986 | 2.935689 | 4.213052 | 0.0003991 | 0.0026189 | 0.0016836 | LAMC2/LMOD1/LAMB3/ACTG2/MYLK/PLD1/TBX18/FAM20C/GLI3/GLI1/FOXF1/PIEZO2/GPC4 | 13 |
| KEGG_AXON_GUIDANCE | KEGG_AXON_GUIDANCE | KEGG_AXON_GUIDANCE | 19/1438 | 129/23056 | 0.1472868 | 2.361505 | 3.999401 | 0.0004081 | 0.0026768 | 0.0017208 | EPHA2/EPHA4/SEMA3B/EPHA3/SLIT2/SEMA5A/ABLIM3/SEMA3C/SEMA3A/SEMA3D/EPHB4/MET/EPHB6/NRP1/RND1/NFATC4/SEMA6B/NFATC2/RAC2 | 19 |
| GOBP_MAINTENANCE_OF_LOCATION | GOBP_MAINTENANCE_OF_LOCATION | GOBP_MAINTENANCE_OF_LOCATION | 37/1438 | 330/23056 | 0.1121212 | 1.797682 | 3.764259 | 0.0004086 | 0.0026786 | 0.0017220 | ZC3H12A/MCOLN2/CASQ1/PTPRC/IKBKE/LTBP1/IL1B/SP100/PPARG/CDS1/ITPR3/MDFI/TRDN/SCIN/IL6/CD36/CAV1/MEST/MSR1/TRPA1/GSN/SRGN/APOA1/UBASH3B/TPCN1/PRKD1/NFKBIA/BDKRB1/FBN1/CES1/CCR7/HAP1/C3/APOE/PLA2G4C/JPH2/KDELR3 | 37 |
| COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | 17/1438 | 109/23056 | 0.1559633 | 2.500619 | 4.050186 | 0.0004104 | 0.0026880 | 0.0017281 | TNFRSF1B/IKBKE/ITGA6/BHLHE40/RBM47/CXCL1/IER3/DDR1/CCN2/PDGFA/SERPINE1/PLAT/NRP1/MAML2/GRB7/SOX9/BCL3 | 17 |
| HP_HEART_BLOCK | HP_HEART_BLOCK | HP_HEART_BLOCK | 17/1438 | 109/23056 | 0.1559633 | 2.500619 | 4.050186 | 0.0004104 | 0.0026880 | 0.0017281 | DES/TNNC1/MYOZ2/GJA1/TRDN/CITED2/SEMA3A/SCNN1A/MMP14/ACTC1/HCN4/MMP2/JUP/KCNJ2/GATA6/SCN1B/GPC4 | 17 |
| HP_ABNORMAL_RIB_CAGE_MORPHOLOGY | HP_ABNORMAL_RIB_CAGE_MORPHOLOGY | HP_ABNORMAL_RIB_CAGE_MORPHOLOGY | 39/1438 | 354/23056 | 0.1101695 | 1.766389 | 3.747773 | 0.0004116 | 0.0026934 | 0.0017315 | MMP23B/HSPG2/FUCA1/PTCH2/TBX15/FGFRL1/FGFR3/NKX3-2/RUNX2/TENT5A/BMPER/GLI3/SHH/GDF6/RSPO2/EXT1/TNFRSF11B/GAS1/FGFR2/CREB3L1/SERPINH1/ZIC2/DACT1/FBN1/SALL1/MAF/FOXF1/MEOX1/COL1A1/NOG/SOX9/PIEZO2/GATA6/TNFRSF11A/RRAS/BMP2/ARSL/GPC4/BGN | 39 |
| HP_ABNORMAL_SCALP_MORPHOLOGY | HP_ABNORMAL_SCALP_MORPHOLOGY | HP_ABNORMAL_SCALP_MORPHOLOGY | 39/1438 | 354/23056 | 0.1101695 | 1.766389 | 3.747773 | 0.0004116 | 0.0026934 | 0.0017315 | HSPG2/PTPN22/TBX15/ECM1/KCNN3/LAMC2/LAMB3/ITGB6/COL3A1/TWIST2/PPARG/COL7A1/SLCO2A1/CLDN1/FGFRL1/FGFR3/TFAP2A/CAV1/GDF6/TRPS1/EXT1/FAS/FGFR2/ALX4/MMP1/IGF1/PRKD1/FOS/MAF/KRT17/JUP/CAVIN1/MEOX1/DLX4/ITGA3/ITGB4/RRAS/RIN2/MID1 | 39 |
| HP_ABNORMALITY_OF_THE_BLADDER | HP_ABNORMALITY_OF_THE_BLADDER | HP_ABNORMALITY_OF_THE_BLADDER | 48/1438 | 464/23056 | 0.1034483 | 1.658626 | 3.696362 | 0.0004131 | 0.0027016 | 0.0017367 | LAMC2/LMOD1/LAMB3/ACTG2/ITGA6/COL3A1/COL5A2/SP110/RARB/COL7A1/MYLK/FGFR3/SNCAIP/SH3TC2/RREB1/GJA1/TMEM270/EPHB4/TRPS1/EXT1/COL5A1/DKK1/FGFR2/HTRA1/MYRF/EFEMP2/CABP4/MMP1/STAT6/GRIP1/FREM2/DACT1/SIX1/FBLN5/SALL1/FOXF1/MYOCD/COL1A1/ITGB4/TGFB1/SIX5/PRNP/MYL9/COL18A1/RAC2/PDGFB/FRMPD4/ARHGEF6 | 48 |
| HP_VENTRICULAR_ARRHYTHMIA | HP_VENTRICULAR_ARRHYTHMIA | HP_VENTRICULAR_ARRHYTHMIA | 25/1438 | 193/23056 | 0.1295337 | 2.076863 | 3.874598 | 0.0004232 | 0.0027663 | 0.0017784 | ECE1/FMO3/KYNU/TNNC1/TECRL/MYOZ2/DSP/HFE/RHAG/TRDN/CITED2/SEMA3A/PYGM/SCNN1A/ACTC1/TPM1/HCN4/JUP/CAVIN1/KCNJ2/GATA6/DSG2/SCN1B/BMP2/JPH2 | 25 |
| GOBP_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION | 11/1438 | 54/23056 | 0.2037037 | 3.266059 | 4.299713 | 0.0004256 | 0.0027797 | 0.0017870 | RARB/WNT5A/HES1/IL31RA/BMP6/EXT1/NOTCH1/FGFR2/BMP4/GATA6/BMP2 | 11 |
| PID_TAP63_PATHWAY | PID_TAP63_PATHWAY | PID_TAP63_PATHWAY | 11/1438 | 54/23056 | 0.2037037 | 3.266059 | 4.299713 | 0.0004256 | 0.0027797 | 0.0017870 | DHRS3/S100A2/PERP/SHH/FAS/MFGE8/NQO1/ITGA3/ITGB4/GDF15/TFAP2C | 11 |
| GOBP_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | 9/1438 | 38/23056 | 0.2368421 | 3.797379 | 4.451062 | 0.0004364 | 0.0028436 | 0.0018281 | TGFB2/CD96/BCL6/HFE/ANGPT1/APOA1/CD22/TGFB1/HMOX1 | 9 |
| GOBP_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION | 9/1438 | 38/23056 | 0.2368421 | 3.797379 | 4.451062 | 0.0004364 | 0.0028436 | 0.0018281 | ERRFI1/FOXC1/CD109/HOXA7/AQP3/NOTCH1/PLAAT4/ZFP36L1/ZFP36 | 9 |
| GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | 9/1438 | 38/23056 | 0.2368421 | 3.797379 | 4.451062 | 0.0004364 | 0.0028436 | 0.0018281 | HES1/SOD2/NOTCH1/ADM/EFEMP2/MYOCD/GATA6/NFATC2/PDGFB | 9 |
| HP_ABNORMALITY_OF_THE_PUBIC_BONE | HP_ABNORMALITY_OF_THE_PUBIC_BONE | HP_ABNORMALITY_OF_THE_PUBIC_BONE | 9/1438 | 38/23056 | 0.2368421 | 3.797379 | 4.451062 | 0.0004364 | 0.0028436 | 0.0018281 | HSPG2/TBX15/NKX3-2/RUNX2/CCN2/CAV1/FGFR2/GRIP1/FREM2 | 9 |
| WP_STRIATED_MUSCLE_CONTRACTION_PATHWAY | WP_STRIATED_MUSCLE_CONTRACTION_PATHWAY | WP_STRIATED_MUSCLE_CONTRACTION_PATHWAY | 9/1438 | 38/23056 | 0.2368421 | 3.797379 | 4.451062 | 0.0004364 | 0.0028436 | 0.0018281 | DES/TNNC1/TPM2/ACTC1/TPM1/MYH8/MYL4/MYOM1/MYL9 | 9 |
| ENK_UV_RESPONSE_EPIDERMIS_UP | ENK_UV_RESPONSE_EPIDERMIS_UP | ENK_UV_RESPONSE_EPIDERMIS_UP | 34/1438 | 296/23056 | 0.1148649 | 1.841672 | 3.758866 | 0.0004442 | 0.0028930 | 0.0018598 | CSF1/MTMR11/ELF3/TGFA/SP110/MYLK/ANXA3/OSMR/SERPINB1/MDFI/THBS2/CD36/AKR1B10/ZYX/IFITM3/EHF/MMP3/ARHGDIB/OASL/PYGL/SERPINA1/ALDH1A3/IL4R/NUPR1/ADAP2/KRT17/COPZ2/ITGB4/DSG2/LIPG/FXYD5/BCL3/PROCR/MX1 | 34 |
| HP_LIMB_PAIN | HP_LIMB_PAIN | HP_LIMB_PAIN | 10/1438 | 46/23056 | 0.2173913 | 3.485517 | 4.352028 | 0.0004458 | 0.0028960 | 0.0018617 | COL5A2/FN1/SLCO2A1/MME/COL5A1/SMAD6/KRT17/COL1A1/TGFB1/COL9A3 | 10 |
| JAEGER_METASTASIS_UP | JAEGER_METASTASIS_UP | JAEGER_METASTASIS_UP | 10/1438 | 46/23056 | 0.2173913 | 3.485517 | 4.352028 | 0.0004458 | 0.0028960 | 0.0018617 | FN1/MME/SPP1/MET/STC1/SULF1/PAPSS2/EPS8/SLC16A3/BGN | 10 |
| LANDIS_BREAST_CANCER_PROGRESSION_UP | LANDIS_BREAST_CANCER_PROGRESSION_UP | LANDIS_BREAST_CANCER_PROGRESSION_UP | 10/1438 | 46/23056 | 0.2173913 | 3.485517 | 4.352028 | 0.0004458 | 0.0028960 | 0.0018617 | GALNT3/ELL2/CRYBG1/ARHGEF5/EHF/CD82/CLDN7/DSG2/KCNN4/TFAP2C | 10 |
| PID_A6B1_A6B4_INTEGRIN_PATHWAY | PID_A6B1_A6B4_INTEGRIN_PATHWAY | PID_A6B1_A6B4_INTEGRIN_PATHWAY | 10/1438 | 46/23056 | 0.2173913 | 3.485517 | 4.352028 | 0.0004458 | 0.0028960 | 0.0018617 | LAMC2/LAMB3/IL1A/ITGA6/LAMB2/EGF/LAMA4/LAMA2/MET/ITGB4 | 10 |
| SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER | SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER | SATO_SILENCED_EPIGENETICALLY_IN_PANCREATIC_CANCER | 10/1438 | 46/23056 | 0.2173913 | 3.485517 | 4.352028 | 0.0004458 | 0.0028960 | 0.0018617 | S100A2/GAS1/SRGN/CRIP1/IL32/SALL1/CLDN7/CSF3/KRT17/SPANXC | 10 |
| GOBP_FIBROBLAST_PROLIFERATION | GOBP_FIBROBLAST_PROLIFERATION | GOBP_FIBROBLAST_PROLIFERATION | 14/1438 | 81/23056 | 0.1728395 | 2.771201 | 4.118480 | 0.0004491 | 0.0029139 | 0.0018732 | AGT/COL3A1/FN1/WNT5A/EREG/PDGFC/SOD2/PDGFA/AQP1/PARP10/IGF1/NUPR1/PDGFB/WNT7B | 14 |
| HP_ABNORMALITIES_OF_PLACENTA_OR_UMBILICAL_CORD | HP_ABNORMALITIES_OF_PLACENTA_OR_UMBILICAL_CORD | HP_ABNORMALITIES_OF_PLACENTA_OR_UMBILICAL_CORD | 14/1438 | 81/23056 | 0.1728395 | 2.771201 | 4.118480 | 0.0004491 | 0.0029139 | 0.0018732 | HSPG2/CFH/FGFR3/CFI/ADGRG6/SERPINE1/PLAG1/WT1/HMGA2/IGF1/FLT1/FOXF1/GATA6/RAC2 | 14 |
| HP_HYPERTRIGLYCERIDEMIA | HP_HYPERTRIGLYCERIDEMIA | HP_HYPERTRIGLYCERIDEMIA | 14/1438 | 81/23056 | 0.1728395 | 2.771201 | 4.118480 | 0.0004491 | 0.0029139 | 0.0018732 | LDLRAP1/PPARG/PSMB8/PSMB9/STX11/CAV1/SLC7A7/PYGL/FOS/PSMB10/CAVIN1/CREB3L3/PLVAP/APOE | 14 |
| HP_LYMPHOPENIA | HP_LYMPHOPENIA | HP_LYMPHOPENIA | 19/1438 | 130/23056 | 0.1461538 | 2.343340 | 3.961391 | 0.0004505 | 0.0029216 | 0.0018782 | GFI1/PTPRC/CASP10/SP110/ADAMTS3/SPP1/FAT4/IL7R/STING1/DOCK2/PSMB9/TNFAIP3/SAMD9/FAS/NFKB2/LAT/ELANE/RAC2/MSN | 19 |
| GOMF_PHOSPHATIDYLINOSITOL_BINDING | GOMF_PHOSPHATIDYLINOSITOL_BINDING | GOMF_PHOSPHATIDYLINOSITOL_BINDING | 32/1438 | 273/23056 | 0.1172161 | 1.879371 | 3.769659 | 0.0004529 | 0.0029345 | 0.0018865 | LDLRAP1/PLA2G4A/CAPG/ESYT3/VEPH1/PLD1/ZFYVE28/ARAP2/MYO10/IQGAP2/PXDC1/ITPR3/SCIN/GSDMD/GSN/ANXA8/PHLDA2/SYTL2/PHLDA1/TPCN1/PLEK2/TNFAIP8L3/MYO1E/ANXA2/GRAMD2A/ADAP2/GRB7/WIPI1/KCNJ2/SDCBP2/JPH2/FRMPD4 | 32 |
| RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | 30/1438 | 250/23056 | 0.1200000 | 1.924006 | 3.788561 | 0.0004537 | 0.0029345 | 0.0018865 | TNFRSF4/RUNX3/NIBAN1/RASGRP3/IL1R1/ITGA4/MGLL/LPP/PLAC8/F2RL1/ADAM19/INHBA/TRAF1/RAB38/BIRC3/CRIP1/ANXA2/IL21R/CCR7/SLC16A5/GADD45B/EBI3/ZFP36/LYPD3/NECTIN2/SDC4/RUNX1/IL13RA1/ARHGEF6/ZNF185 | 30 |
| GOBP_INTERLEUKIN_2_PRODUCTION | GOBP_INTERLEUKIN_2_PRODUCTION | GOBP_INTERLEUKIN_2_PRODUCTION | 12/1438 | 63/23056 | 0.1904762 | 3.053977 | 4.210390 | 0.0004538 | 0.0029345 | 0.0018865 | GBP1/PTPRC/CD34/IL1A/IL1B/TNFAIP3/ANXA1/SFTPD/NAV3/ZFP36/PRNP/RUNX1 | 12 |
| GOBP_REGULATION_OF_STEM_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_STEM_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 12/1438 | 63/23056 | 0.1904762 | 3.053977 | 4.210390 | 0.0004538 | 0.0029345 | 0.0018865 | TGFB2/LBH/HES1/GDNF/FOXC1/RBM24/PTN/NOTCH1/YAP1/ESRRB/SOX9/GATA6 | 12 |
| HP_HEPATOCELLULAR_CARCINOMA | HP_HEPATOCELLULAR_CARCINOMA | HP_HEPATOCELLULAR_CARCINOMA | 12/1438 | 63/23056 | 0.1904762 | 3.053977 | 4.210390 | 0.0004538 | 0.0029345 | 0.0018865 | CASP10/CASP8/TGFBR2/HFE/MET/PDGFRL/TNFSF15/FAS/PYGL/SERPINA1/IL12RB1/BMP2 | 12 |
| HP_OSTEOARTHRITIS | HP_OSTEOARTHRITIS | HP_OSTEOARTHRITIS | 12/1438 | 63/23056 | 0.1904762 | 3.053977 | 4.210390 | 0.0004538 | 0.0029345 | 0.0018865 | PTPN22/COL3A1/COL5A2/FGFR3/TENT5A/TRPS1/TNFRSF11B/COL5A1/FBN1/COL1A1/COL9A3/IL2RB | 12 |
| HP_ABNORMAL_ESOPHAGUS_MORPHOLOGY | HP_ABNORMAL_ESOPHAGUS_MORPHOLOGY | HP_ABNORMAL_ESOPHAGUS_MORPHOLOGY | 26/1438 | 205/23056 | 0.1268293 | 2.033502 | 3.833450 | 0.0004562 | 0.0029458 | 0.0018937 | LAMC2/PLA2G4A/LAMB3/TGFB2/ITGA6/TGFBR2/COL7A1/ADAMTS2/TMEM270/SAMD9/MSR1/FGF20/CTHRC1/COL14A1/NOTCH1/ITGA8/FGFR2/MMP1/KRT8/KRT18/FOXF1/ITGB4/RHBDF2/TGFB1/COL4A6/COL4A5 | 26 |
| KYNG_DNA_DAMAGE_UP | KYNG_DNA_DAMAGE_UP | KYNG_DNA_DAMAGE_UP | 26/1438 | 205/23056 | 0.1268293 | 2.033502 | 3.833450 | 0.0004562 | 0.0029458 | 0.0018937 | SYNC/TIE1/VCAM1/CRABP2/ITPKB/IL1R1/HNMT/CYBRD1/NRP2/WNT5A/MITF/SLCO2A1/ADAMTS3/HBEGF/DOCK2/CYP39A1/PTPRK/MET/PCSK5/C3AR1/H2AJ/PHLDA1/CYP19A1/LDHD/DLX4/SOX9 | 26 |
| SHEPARD_CRASH_AND_BURN_MUTANT_UP | SHEPARD_CRASH_AND_BURN_MUTANT_UP | SHEPARD_CRASH_AND_BURN_MUTANT_UP | 26/1438 | 205/23056 | 0.1268293 | 2.033502 | 3.833450 | 0.0004562 | 0.0029458 | 0.0018937 | CCN1/PTGS2/CASP8/FN1/HES1/SLC12A7/FST/RNF144B/TCIM/ANKRD22/CYP26A1/PHLDA2/MS4A4A/SERPINH1/PPM1H/FOS/MMP2/KRT17/NOG/GADD45B/KLF2/CRLS1/BMP2/CEBPB/CYP24A1/SAT1 | 26 |
| GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | 25/1438 | 194/23056 | 0.1288660 | 2.066157 | 3.846088 | 0.0004576 | 0.0029528 | 0.0018983 | CCN1/NID1/RTP4/P3H2/ARSJ/HBEGF/HLA-E/THBS2/HOXA7/AKR1B10/ZNF467/CSGALNACT1/S1PR3/NRP1/HTRA1/SYT12/C3AR1/PPM1H/NAV3/FLT1/TNFAIP2/MYOCD/GATA6/TGM2/MYH9 | 25 |
| HP_PURPURA | HP_PURPURA | HP_PURPURA | 17/1438 | 110/23056 | 0.1545455 | 2.477886 | 4.007172 | 0.0004577 | 0.0029528 | 0.0018983 | PTPN22/CFH/NLRP3/COL3A1/COL5A2/NABP1/CASP10/ITGA2/RREB1/CD109/STX11/SAMD9/COL5A1/NFKB2/COL1A1/APOE/USP18 | 17 |
| HP_MYOPATHY | HP_MYOPATHY | HP_MYOPATHY | 37/1438 | 332/23056 | 0.1114458 | 1.786853 | 3.724554 | 0.0004588 | 0.0029583 | 0.0019018 | AGRN/MMP23B/HSPG2/NEXN/CASQ1/DES/COL6A3/PPARG/LAMB2/TNNC1/DOK7/DSP/CAP2/COL12A1/LAMA4/ADGRG6/TMEM270/FLNC/SHH/B4GALT1/TPM2/GAS1/MYPN/COL13A1/VCL/ANKRD1/BAG3/CRYAB/ITGA7/ZIC2/ACTC1/TPM1/MYH2/SGCA/DSG2/COL9A3/COL6A2 | 37 |
| GOBP_NON_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_NON_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_NON_CANONICAL_WNT_SIGNALING_PATHWAY | 13/1438 | 72/23056 | 0.1805556 | 2.894916 | 4.153341 | 0.0004596 | 0.0029596 | 0.0019026 | WNT5A/PRICKLE2/DAB2/RSPO3/FZD1/FZD6/CTHRC1/FZD8/DKK1/FZD4/DACT1/CELSR1/GPC4 | 13 |
| WP_P53_TRANSCRIPTIONAL_GENE_NETWORK | WP_P53_TRANSCRIPTIONAL_GENE_NETWORK | WP_P53_TRANSCRIPTIONAL_GENE_NETWORK | 13/1438 | 72/23056 | 0.1805556 | 2.894916 | 4.153341 | 0.0004596 | 0.0029596 | 0.0019026 | FUCA1/RPRM/SLC7A11/PERP/SERPINE1/NOTCH1/FAS/DRAM1/IRF9/THBS1/ICAM1/LIF/SAT1 | 13 |
| YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | 13/1438 | 72/23056 | 0.1805556 | 2.894916 | 4.153341 | 0.0004596 | 0.0029596 | 0.0019026 | CFH/LAMB3/AOX1/ADRB2/HLA-E/PLA2G7/NT5E/SASH1/MET/CEBPD/CASP4/EPS8/RIN2 | 13 |
| HP_DIARRHEA | HP_DIARRHEA | HP_DIARRHEA | 38/1438 | 344/23056 | 0.1104651 | 1.771129 | 3.716489 | 0.0004602 | 0.0029620 | 0.0019041 | ECE1/GFI1/FCGR2A/CFH/PTPRC/ACTG2/LCT/ITGA6/CASP8/DES/SP110/SLCO2A1/SPP1/IL7R/GDNF/ITGA2/PCSK1/CD109/IL6/SEMA3C/SEMA3D/SAMD9/PODXL/SAA1/TNFRSF1A/SCNN1A/EDNRB/SLC10A2/SLC7A7/IL21R/ITGB4/GATA6/ELANE/CACNA1A/PLVAP/TGFB1/RUNX1/IL2RB | 38 |
| GOBP_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 34/1438 | 297/23056 | 0.1144781 | 1.835471 | 3.737553 | 0.0004723 | 0.0030385 | 0.0019533 | TNFRSF1B/S100A10/CRABP2/IL1B/FN1/EPHA4/SERPINE2/MME/HES1/SLIT2/VEGFC/SEMA5A/DAB2/RREB1/IL6/GLI3/PTPRZ1/PTN/SHH/PLAG1/HAS2/NOTCH1/NRP1/APOA1/BMP4/BNC1/SOX8/TRPV2/HAP1/MAG/TGFB1/BMP2/TGM2/LIF | 34 |
| MANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_COMBINED_COHORT_VS_HEALTHY_DONOR_PLATELETS_DN | 28/1438 | 228/23056 | 0.1228070 | 1.969011 | 3.792422 | 0.0004772 | 0.0030685 | 0.0019726 | TNFSF18/CD34/TGFB2/WNT9A/CAVIN2/ACKR2/KDR/CXCL6/CXCL5/IL7R/TGFBI/CLIC5/TNFRSF21/UTRN/SASH1/SCIN/PDCD1LG2/PAPPA/MYOF/MYEOV/YAP1/ALDH1A2/CAVIN1/SMIM36/SERPINB8/APCDD1L/MAP3K7CL/LGALS2 | 28 |
| HP_ABNORMAL_CEREBRAL_VASCULAR_MORPHOLOGY | HP_ABNORMAL_CEREBRAL_VASCULAR_MORPHOLOGY | HP_ABNORMAL_CEREBRAL_VASCULAR_MORPHOLOGY | 35/1438 | 309/23056 | 0.1132686 | 1.816079 | 3.724804 | 0.0004788 | 0.0030771 | 0.0019781 | LDLRAP1/CFH/TGFB2/COL3A1/COL5A2/CPS1/FN1/TGFBR2/MYLK/CFI/ITGA2/SPARC/EDN1/CD109/TENT5A/CITED2/IL6/TMEM270/SAMD9/EPHB4/SERPINE1/FLNC/COL5A1/MYPN/HTRA1/ALX4/ALOX5AP/ACTC1/FBN1/COL1A1/GATA6/PRNP/USP18/PDGFB/BGN | 35 |
| GOBP_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | GOBP_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | GOBP_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 20/1438 | 141/23056 | 0.1418440 | 2.274238 | 3.914304 | 0.0004807 | 0.0030878 | 0.0019851 | TGFB2/AGT/TGFBR2/WNT5A/EGF/PDGFC/TLR3/ADRB2/TNFRSF10A/ANGPT1/ADCY8/TNFSF15/GPRC5A/NCKAP1L/IGF1/CCL5/GPRC5C/PRNP/CARD10/PDGFB | 20 |
| DASU_IL6_SIGNALING_SCAR_UP | DASU_IL6_SIGNALING_SCAR_UP | DASU_IL6_SIGNALING_SCAR_UP | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | AGRN/LTBP1/TMEM158/MME/NT5E/MOXD1/MAF/ZFP36 | 8 |
| GOBP_CARTILAGE_DEVELOPMENT_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS | GOBP_CARTILAGE_DEVELOPMENT_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS | GOBP_CARTILAGE_DEVELOPMENT_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | RARB/TGFBR2/STC1/EXT1/COL27A1/SERPINH1/COL1A1/SOX9 | 8 |
| GOBP_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT | GOBP_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT | GOBP_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | WNT5A/NOTCH1/DKK1/BMP4/NOG/ALPK2/TGFB1/BMP2 | 8 |
| GOBP_EMBRYONIC_FORELIMB_MORPHOGENESIS | GOBP_EMBRYONIC_FORELIMB_MORPHOGENESIS | GOBP_EMBRYONIC_FORELIMB_MORPHOGENESIS | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | CRABP2/OSR1/TFAP2A/RUNX2/SHH/RSPO2/ALX4/ALDH1A2 | 8 |
| GOBP_ENDOTHELIAL_CELL_CHEMOTAXIS | GOBP_ENDOTHELIAL_CELL_CHEMOTAXIS | GOBP_ENDOTHELIAL_CELL_CHEMOTAXIS | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | KDR/SEMA5A/FGF18/MET/NOTCH1/NRP1/PRKD1/THBS1 | 8 |
| GOBP_HEART_TRABECULA_MORPHOGENESIS | GOBP_HEART_TRABECULA_MORPHOGENESIS | GOBP_HEART_TRABECULA_MORPHOGENESIS | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | S1PR1/TGFB2/BMP10/HEG1/ADGRG6/TEK/NOTCH1/NOG | 8 |
| GOBP_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY | GOBP_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY | GOBP_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | DHRS3/CYP26B1/PPARG/RARB/AKR1C3/CYP26A1/ALDH1A2/KLF2 | 8 |
| GOMF_MICROFILAMENT_MOTOR_ACTIVITY | GOMF_MICROFILAMENT_MOTOR_ACTIVITY | GOMF_MICROFILAMENT_MOTOR_ACTIVITY | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | MYO10/ACTC1/MYO1E/MYH13/MYH8/MYH4/MYH2/MYH9 | 8 |
| GOMF_PROTEIN_LIPID_COMPLEX_BINDING | GOMF_PROTEIN_LIPID_COMPLEX_BINDING | GOMF_PROTEIN_LIPID_COMPLEX_BINDING | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | STAB1/CD36/MSR1/APOA1/THBS1/CDH13/COLEC12/APOE | 8 |
| REACTOME_EGFR_DOWNREGULATION | REACTOME_EGFR_DOWNREGULATION | REACTOME_EGFR_DOWNREGULATION | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | TGFA/EPGN/EREG/BTC/EGF/HBEGF/PTPRK/PTPN3 | 8 |
| REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT | REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT | REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | WWTR1/HES1/RUNX2/GLI3/YAP1/SMAD6/MAF/COL1A1 | 8 |
| SIMBULAN_PARP1_TARGETS_UP | SIMBULAN_PARP1_TARGETS_UP | SIMBULAN_PARP1_TARGETS_UP | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | TINAGL1/SERPINE2/COL8A1/ANXA3/FST/CAV1/IGFBP6/COL4A5 | 8 |
| THEODOROU_MAMMARY_TUMORIGENESIS | THEODOROU_MAMMARY_TUMORIGENESIS | THEODOROU_MAMMARY_TUMORIGENESIS | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | NKD2/RREB1/RSPO3/RSPO2/MAP3K8/FGFR2/PTGIS/TENM1 | 8 |
| VALK_AML_CLUSTER_13 | VALK_AML_CLUSTER_13 | VALK_AML_CLUSTER_13 | 8/1438 | 31/23056 | 0.2580645 | 4.137646 | 4.508575 | 0.0004864 | 0.0031015 | 0.0019938 | HSPG2/STK32B/CAV1/C11orf21/MYRF/LCP1/FBLN5/ITGB4 | 8 |
| GOBP_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | GOBP_REGULATION_OF_SIGNALING_RECEPTOR_ACTIVITY | 23/1438 | 173/23056 | 0.1329480 | 2.131605 | 3.853149 | 0.0004877 | 0.0031015 | 0.0019938 | ERRFI1/CNIH3/TGFA/LYPD1/PPARG/ZFYVE28/EPGN/EREG/BTC/EGF/CRHBP/HBEGF/ADRB2/EDN1/HFE/SERPINE1/NRP1/DKK1/PLAU/PHLDA2/GPRC5A/SLC24A4/NOG | 23 |
| GOBP_FIBRINOLYSIS | GOBP_FIBRINOLYSIS | GOBP_FIBRINOLYSIS | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | FAP/SERPINE1/PLAT/PLAU/THBS1/SERPINB2/THBD | 7 |
| GOBP_OLEFINIC_COMPOUND_BIOSYNTHETIC_PROCESS | GOBP_OLEFINIC_COMPOUND_BIOSYNTHETIC_PROCESS | GOBP_OLEFINIC_COMPOUND_BIOSYNTHETIC_PROCESS | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | SRD5A2/DAB2/BMP6/AKR1C3/ADM/CYP19A1/BMP2 | 7 |
| GOBP_ORGAN_INDUCTION | GOBP_ORGAN_INDUCTION | GOBP_ORGAN_INDUCTION | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | WNT5A/GDNF/DKK1/BMP4/SIX1/BMP2/GATA5 | 7 |
| GOBP_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | GOBP_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | GOBP_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | KDR/SEMA5A/FGF18/MET/NOTCH1/PRKD1/THBS1 | 7 |
| HP_CALVARIAL_SKULL_DEFECT | HP_CALVARIAL_SKULL_DEFECT | HP_CALVARIAL_SKULL_DEFECT | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | HSPG2/NOTCH1/ALX4/GRIP1/FREM2/ITGB4/COL18A1 | 7 |
| HP_INCREASED_CIRCULATING_IGA_LEVEL | HP_INCREASED_CIRCULATING_IGA_LEVEL | HP_INCREASED_CIRCULATING_IGA_LEVEL | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | CASP10/IL7R/STING1/PSMB8/TNFSF15/FAS/IL12RB1 | 7 |
| REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING | REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING | REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | TGFA/EPGN/EREG/BTC/EGF/HBEGF/FOS | 7 |
| REACTOME_INTERLEUKIN_6_FAMILY_SIGNALING | REACTOME_INTERLEUKIN_6_FAMILY_SIGNALING | REACTOME_INTERLEUKIN_6_FAMILY_SIGNALING | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | OSMR/IL31RA/IL6/CTF1/SOCS3/IL11/LIF | 7 |
| REACTOME_RUNX2_REGULATES_OSTEOBLAST_DIFFERENTIATION | REACTOME_RUNX2_REGULATES_OSTEOBLAST_DIFFERENTIATION | REACTOME_RUNX2_REGULATES_OSTEOBLAST_DIFFERENTIATION | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | WWTR1/HES1/RUNX2/GLI3/YAP1/MAF/COL1A1 | 7 |
| WANG_NFKB_TARGETS | WANG_NFKB_TARGETS | WANG_NFKB_TARGETS | 7/1438 | 24/23056 | 0.2916667 | 4.676402 | 4.647475 | 0.0004884 | 0.0031015 | 0.0019938 | TNNC1/ITGB5/HOXA1/NOTCH1/ACTC1/MYH1/MYL4 | 7 |
| HP_INGUINAL_HERNIA | HP_INGUINAL_HERNIA | HP_INGUINAL_HERNIA | 31/1438 | 263/23056 | 0.1178707 | 1.889866 | 3.743312 | 0.0005013 | 0.0031814 | 0.0020452 | HSPG2/TGFB2/COL3A1/COL5A2/TGFBR2/WNT5A/MYLK/PLD1/SEMA5A/ADAMTS2/RREB1/TENT5A/BMPER/GLI3/TMEM270/PLAG1/COL5A1/NOTCH1/EFEMP2/SERPINH1/C1S/C1R/HMGA2/FBLN5/FBN1/LDHD/MAF/COL1A1/PIEZO2/GATA6/GPC4 | 31 |
| GOBP_REGULATION_OF_ACTOMYOSIN_STRUCTURE_ORGANIZATION | GOBP_REGULATION_OF_ACTOMYOSIN_STRUCTURE_ORGANIZATION | GOBP_REGULATION_OF_ACTOMYOSIN_STRUCTURE_ORGANIZATION | 16/1438 | 101/23056 | 0.1584158 | 2.539941 | 4.000189 | 0.0005024 | 0.0031814 | 0.0020452 | S1PR1/RHOC/S100A10/BMP10/PHLDB2/EDN1/CCN2/MET/ARHGEF5/NRP1/SYNPO2L/APOA1/CGNL1/TPM1/MYLK3/SDC4 | 16 |
| KEGG_MELANOGENESIS | KEGG_MELANOGENESIS | KEGG_MELANOGENESIS | 16/1438 | 101/23056 | 0.1584158 | 2.539941 | 4.000189 | 0.0005024 | 0.0031814 | 0.0020452 | WNT9A/WNT5A/MITF/LEF1/EDN1/FZD1/FZD6/ADCY8/FZD8/TCF7L2/CREB3L1/FZD4/WNT10B/EDNRB/CREB3L3/WNT7B | 16 |
| GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | 11/1438 | 55/23056 | 0.2000000 | 3.206676 | 4.225721 | 0.0005024 | 0.0031814 | 0.0020452 | PTPRC/CD96/BCL6/IL7R/HFE/HLA-E/MICA/AHR/KLRD1/NCKAP1L/IL4I1 | 11 |
| GOCC_BRUSH_BORDER_MEMBRANE | GOCC_BRUSH_BORDER_MEMBRANE | GOCC_BRUSH_BORDER_MEMBRANE | 11/1438 | 55/23056 | 0.2000000 | 3.206676 | 4.225721 | 0.0005024 | 0.0031814 | 0.0020452 | CYBRD1/SLC34A2/ABCG2/SLC7A11/AQP1/CD36/SLC26A4/ATP6V0A4/B4GALT1/TRPM6/SLC28A1 | 11 |
| WP_RANKLRANK_SIGNALING_PATHWAY | WP_RANKLRANK_SIGNALING_PATHWAY | WP_RANKLRANK_SIGNALING_PATHWAY | 11/1438 | 55/23056 | 0.2000000 | 3.206676 | 4.225721 | 0.0005024 | 0.0031814 | 0.0020452 | VCAM1/MITF/TNFRSF11B/TRAF1/PAPSS2/NFKB2/NFKBIA/FOS/TNFRSF11A/ICAM1/RELB | 11 |
| GOBP_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT | 21/1438 | 152/23056 | 0.1381579 | 2.215138 | 3.876555 | 0.0005035 | 0.0031867 | 0.0020486 | EPHA2/HSPG2/TIE1/ATP2B4/TGFB2/AGT/PPARG/STAB1/PLK2/SPARC/FOXC1/THBS2/SERPINE1/SULF1/TEK/KLF4/ALOX5/HHEX/CREB3L1/THBS1/KLF2 | 21 |
| GOBP_AXON_EXTENSION | GOBP_AXON_EXTENSION | GOBP_AXON_EXTENSION | 18/1438 | 121/23056 | 0.1487603 | 2.385131 | 3.939929 | 0.0005070 | 0.0032062 | 0.0020612 | EDN2/NRP2/FN1/LAMB2/SEMA3B/WNT5A/SLIT2/SEMA5A/EDN1/SEMA3C/SEMA3A/SEMA3D/NRP1/VCL/TRPV2/SEMA6B/MAG/APOE | 18 |
| HP_PULMONARY_HYPOPLASIA | HP_PULMONARY_HYPOPLASIA | HP_PULMONARY_HYPOPLASIA | 18/1438 | 121/23056 | 0.1487603 | 2.385131 | 3.939929 | 0.0005070 | 0.0032062 | 0.0020612 | HSPG2/AGT/RARB/DOK7/TENT5A/ADGRG6/FAM20C/BMPER/FGF20/ZFPM2/ITGA8/WT1/MYRF/GRIP1/FREM2/GLDN/PIEZO2/GATA6 | 18 |
| GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | 14/1438 | 82/23056 | 0.1707317 | 2.737406 | 4.064847 | 0.0005110 | 0.0032165 | 0.0020678 | RUNX3/ZC3H12A/NLRP3/BCL6/LEF1/IL6/ANXA1/NCKAP1L/STAT6/IL4R/IL12RB1/BCL3/RELB/RUNX1 | 14 |
| HP_BONE_PAIN | HP_BONE_PAIN | HP_BONE_PAIN | 14/1438 | 82/23056 | 0.1707317 | 2.737406 | 4.064847 | 0.0005110 | 0.0032165 | 0.0020678 | NABP1/SLCO2A1/PSMB8/TENT5A/TRPS1/EXT1/TEK/DKK1/TNFRSF1A/CYP19A1/TNFRSF11A/ELANE/TGFB1/RUNX1 | 14 |
| HP_OMPHALOCELE | HP_OMPHALOCELE | HP_OMPHALOCELE | 14/1438 | 82/23056 | 0.1707317 | 2.737406 | 4.064847 | 0.0005110 | 0.0032165 | 0.0020678 | LMOD1/ACTG2/TWIST2/CD96/MYLK/SHH/GRIP1/FREM2/ZIC2/MMP14/DACT1/MMP2/FOXF1/GPC4 | 14 |
| GOBP_ADHESION_OF_SYMBIONT_TO_HOST_CELL | GOBP_ADHESION_OF_SYMBIONT_TO_HOST_CELL | GOBP_ADHESION_OF_SYMBIONT_TO_HOST_CELL | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | LRRC15/SFTPD/CLEC4M/ICAM1/NECTIN2 | 5 |
| GOBP_COLLAGEN_ACTIVATED_TYROSINE_KINASE_RECEPTOR_SIGNALING_PATHWAY | GOBP_COLLAGEN_ACTIVATED_TYROSINE_KINASE_RECEPTOR_SIGNALING_PATHWAY | GOBP_COLLAGEN_ACTIVATED_TYROSINE_KINASE_RECEPTOR_SIGNALING_PATHWAY | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | DDR1/UBASH3B/COL1A1/COL4A6/COL4A5 | 5 |
| GOBP_GLOMERULAR_MESANGIAL_CELL_PROLIFERATION | GOBP_GLOMERULAR_MESANGIAL_CELL_PROLIFERATION | GOBP_GLOMERULAR_MESANGIAL_CELL_PROLIFERATION | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | PDGFA/WT1/BMP4/SERPINB7/PDGFB | 5 |
| GOBP_NEGATIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | DLX1/DLX2/HES1/ID4/NOTCH1 | 5 |
| GOBP_NEGATIVE_T_CELL_SELECTION | GOBP_NEGATIVE_T_CELL_SELECTION | GOBP_NEGATIVE_T_CELL_SELECTION | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | PTPRC/DOCK2/GLI3/SHH/CCR7 | 5 |
| GOBP_POSITIVE_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT | GOBP_POSITIVE_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | TGFB2/WNT5A/FST/WNT10B/KRT17 | 5 |
| GOBP_POSITIVE_REGULATION_OF_PODOSOME_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_PODOSOME_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_PODOSOME_ASSEMBLY | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | CAPG/CSF2/ARHGEF5/LCP1/MSN | 5 |
| GOBP_POSITIVE_REGULATION_OF_VASCULOGENESIS | GOBP_POSITIVE_REGULATION_OF_VASCULOGENESIS | GOBP_POSITIVE_REGULATION_OF_VASCULOGENESIS | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | CD34/KDR/ADM/RRAS/RIN2 | 5 |
| GOBP_PROSTATE_GLAND_GROWTH | GOBP_PROSTATE_GLAND_GROWTH | GOBP_PROSTATE_GLAND_GROWTH | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | SHH/PLAG1/FGFR2/CYP19A1/SOX9 | 5 |
| GOBP_SKIN_MORPHOGENESIS | GOBP_SKIN_MORPHOGENESIS | GOBP_SKIN_MORPHOGENESIS | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | ERRFI1/ITGA6/ITGA2/COL1A1/ITGB4 | 5 |
| GOMF_PROTEIN_BINDING_INVOLVED_IN_HETEROTYPIC_CELL_CELL_ADHESION | GOMF_PROTEIN_BINDING_INVOLVED_IN_HETEROTYPIC_CELL_CELL_ADHESION | GOMF_PROTEIN_BINDING_INVOLVED_IN_HETEROTYPIC_CELL_CELL_ADHESION | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | DSP/GLDN/JUP/DSG2/SIRPA | 5 |
| HP_2_3_FINGER_SYNDACTYLY | HP_2_3_FINGER_SYNDACTYLY | HP_2_3_FINGER_SYNDACTYLY | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | FGFR3/DSP/FGFR2/JUP/GPC4 | 5 |
| HP_CARDIAC_VALVE_CALCIFICATION | HP_CARDIAC_VALVE_CALCIFICATION | HP_CARDIAC_VALVE_CALCIFICATION | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | SLC34A2/NOTCH1/FBN1/SMAD6/GATA5 | 5 |
| HP_TRICUSPID_VALVE_PROLAPSE | HP_TRICUSPID_VALVE_PROLAPSE | HP_TRICUSPID_VALVE_PROLAPSE | 5/1438 | 12/23056 | 0.4166667 | 6.680575 | 5.076428 | 0.0005126 | 0.0032165 | 0.0020678 | COL5A2/PLD1/COL5A1/FBN1/COL1A1 | 5 |
| LIAN_LIPA_TARGETS_3M | LIAN_LIPA_TARGETS_3M | LIAN_LIPA_TARGETS_3M | 12/1438 | 64/23056 | 0.1875000 | 3.006259 | 4.145174 | 0.0005273 | 0.0033055 | 0.0021250 | FCGR2A/CXCL3/PLA2G7/UTRN/GPNMB/MSR1/SLC15A3/C3AR1/TNFAIP2/CD68/GDF15/HMOX1 | 12 |
| GOBP_B_CELL_DIFFERENTIATION | GOBP_B_CELL_DIFFERENTIATION | GOBP_B_CELL_DIFFERENTIATION | 20/1438 | 142/23056 | 0.1408451 | 2.258223 | 3.878872 | 0.0005273 | 0.0033055 | 0.0021250 | VCAM1/PTPRC/ITGA4/BCL6/IL6/INHBA/ST3GAL1/IFNE/HHEX/PTPRJ/NCKAP1L/FLT3/TNFSF13B/MMP14/ZFP36L1/BCL3/IL4I1/IL11/LGALS1/ITM2A | 20 |
| GOBP_LYMPHOCYTE_COSTIMULATION | GOBP_LYMPHOCYTE_COSTIMULATION | GOBP_LYMPHOCYTE_COSTIMULATION | 10/1438 | 47/23056 | 0.2127660 | 3.411357 | 4.267916 | 0.0005349 | 0.0033472 | 0.0021518 | DPP4/CAV1/CD274/PDCD1LG2/MAP3K8/KLRC4-KLRK1/TNFSF13B/CCR7/TNFSF14/LGALS1 | 10 |
| GOMF_SCAVENGER_RECEPTOR_ACTIVITY | GOMF_SCAVENGER_RECEPTOR_ACTIVITY | GOMF_SCAVENGER_RECEPTOR_ACTIVITY | 10/1438 | 47/23056 | 0.2127660 | 3.411357 | 4.267916 | 0.0005349 | 0.0033472 | 0.0021518 | PRG4/ACKR3/ACKR2/STAB1/CFI/CD36/MSR1/LOXL2/LOXL4/COLEC12 | 10 |
| HUANG_FOXA2_TARGETS_UP | HUANG_FOXA2_TARGETS_UP | HUANG_FOXA2_TARGETS_UP | 10/1438 | 47/23056 | 0.2127660 | 3.411357 | 4.267916 | 0.0005349 | 0.0033472 | 0.0021518 | ACTG2/FN1/ACKR3/SLC7A11/FST/TNFAIP3/CADPS2/RBPMS/CPM/RELB | 10 |
| YANG_BREAST_CANCER_ESR1_LASER_DN | YANG_BREAST_CANCER_ESR1_LASER_DN | YANG_BREAST_CANCER_ESR1_LASER_DN | 10/1438 | 47/23056 | 0.2127660 | 3.411357 | 4.267916 | 0.0005349 | 0.0033472 | 0.0021518 | PLD1/FNDC3B/SEL1L3/FOXC1/CYP39A1/ANXA1/TCF7L2/BBOX1/PRNP/PLS3 | 10 |
| GOBP_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | GOBP_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | GOBP_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | 9/1438 | 39/23056 | 0.2307692 | 3.700011 | 4.352389 | 0.0005363 | 0.0033527 | 0.0021553 | KCNE4/DSP/CAV1/KCNA5/HCN4/JUP/KCNJ2/DSG2/SCN1B | 9 |
| GOCC_PROTEIN_LIPID_COMPLEX | GOCC_PROTEIN_LIPID_COMPLEX | GOCC_PROTEIN_LIPID_COMPLEX | 9/1438 | 39/23056 | 0.2307692 | 3.700011 | 4.352389 | 0.0005363 | 0.0033527 | 0.0021553 | PLA2G7/MSR1/CLU/SAA1/APOC3/APOA1/CETP/APOE/APOL1 | 9 |
| GOBP_PROTEIN_LOCALIZATION_TO_EXTRACELLULAR_REGION | GOBP_PROTEIN_LOCALIZATION_TO_EXTRACELLULAR_REGION | GOBP_PROTEIN_LOCALIZATION_TO_EXTRACELLULAR_REGION | 39/1438 | 359/23056 | 0.1086351 | 1.741788 | 3.653397 | 0.0005425 | 0.0033899 | 0.0021793 | C1QTNF12/ILDR2/TGFB2/LTBP1/IL1A/IL1B/PPARG/SUCNR1/VEGFC/F2RL1/PCSK1/BMP6/ADTRP/IL6/CTAGE4/CTAGE8/ADAM9/ADCY8/ANXA1/PCSK5/ALOX5/ANKRD1/TCF7L2/SAA1/KCNA5/IGF1/EDNRB/LTBP2/FBN1/RHBDF1/CCL5/CAVIN1/GIP/LLGL2/RHBDF2/MYOM1/TGFB1/KCNN4/APOE | 39 |
| GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | GOBP_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 15/1438 | 92/23056 | 0.1630435 | 2.614138 | 4.000968 | 0.0005444 | 0.0033985 | 0.0021848 | ECM1/PTPRC/PPARG/PARP14/SLIT2/F2RL1/IL6/CAV1/KLF4/CARD16/APOA1/NLRC5/CCL5/BIRC7/USP18 | 15 |
| GOBP_REGULATION_OF_LIPASE_ACTIVITY | GOBP_REGULATION_OF_LIPASE_ACTIVITY | GOBP_REGULATION_OF_LIPASE_ACTIVITY | 15/1438 | 92/23056 | 0.1630435 | 2.614138 | 4.000968 | 0.0005444 | 0.0033985 | 0.0021848 | CCN1/RHOC/AGT/FGFR3/TXK/ANXA1/PCSK5/ANXA8L1/ANXA8/FGFR2/APOC3/APOA1/FLT1/CCL5/C5AR1 | 15 |
| GOBP_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS | GOBP_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS | GOBP_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS | 19/1438 | 132/23056 | 0.1439394 | 2.307835 | 3.886413 | 0.0005470 | 0.0034101 | 0.0021923 | PTGS2/ATP2B4/IL1B/PPARG/SLC7A11/DAB2/BMP6/PDK4/CAV1/ANXA1/AKR1C3/ADM/APOC3/APOA1/SLC7A7/CES1/GIP/SOX9/BMP2 | 19 |
| GOBP_STEROL_TRANSPORT | GOBP_STEROL_TRANSPORT | GOBP_STEROL_TRANSPORT | 19/1438 | 132/23056 | 0.1439394 | 2.307835 | 3.886413 | 0.0005470 | 0.0034101 | 0.0021923 | LDLRAP1/PPARG/OSBPL10/EGF/CD36/CAV1/SHH/MSR1/CLU/APOC3/APOA1/SOAT2/NFKBIA/ANXA2/CES1/CETP/ABCA8/LIPG/APOE | 19 |
| HP_ABNORMALITY_OF_THE_PYLORUS | HP_ABNORMALITY_OF_THE_PYLORUS | HP_ABNORMALITY_OF_THE_PYLORUS | 19/1438 | 132/23056 | 0.1439394 | 2.307835 | 3.886413 | 0.0005470 | 0.0034101 | 0.0021923 | MMP23B/HSPG2/LAMC2/LAMB3/ITGA6/ADAMTS3/FAT4/TFAP2A/NFKB2/FGFR2/EFEMP2/SERPINH1/FBLN5/CAVIN1/ITGB4/PIEZO2/COL18A1/FRMPD4/ARHGEF6 | 19 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION | 46/1438 | 445/23056 | 0.1033708 | 1.657383 | 3.611544 | 0.0005477 | 0.0034129 | 0.0021941 | C1QTNF12/ARHGEF16/EPHA2/ZC3H12A/PTGS2/ATP2B4/TGFB2/IL1A/IL1B/PPARG/WNT5A/EPHA3/WWTR1/EGF/VEGFC/NKD2/F2RL1/PCSK1/ABLIM3/BMP6/MICALL2/GLI3/TCAF2/ARHGEF5/SHH/ADAM9/ADCY8/ANKRD1/TCF7L2/BAG3/YAP1/IGF1/PRKD1/JUP/GIP/ITGA3/PECAM1/MYOM1/TGFB1/KCNN4/PRNP/LIF/RAC2/CARD10/MSN/TENM1 | 46 |
| HP_ABNORMAL_MITRAL_VALVE_PHYSIOLOGY | HP_ABNORMAL_MITRAL_VALVE_PHYSIOLOGY | HP_ABNORMAL_MITRAL_VALVE_PHYSIOLOGY | 21/1438 | 153/23056 | 0.1372549 | 2.200660 | 3.843030 | 0.0005500 | 0.0034242 | 0.0022013 | LDLRAP1/COL5A2/PLD1/GJA1/CITED2/TMEM270/FLNC/COL5A1/NOTCH1/MYPN/FAS/CRYAB/LTBP2/FBLN5/ACTC1/FBN1/TPM1/ALPK3/COL1A1/GATA6/BGN | 21 |
| HP_CHRONIC_KIDNEY_DISEASE | HP_CHRONIC_KIDNEY_DISEASE | HP_CHRONIC_KIDNEY_DISEASE | 21/1438 | 153/23056 | 0.1372549 | 2.200660 | 3.843030 | 0.0005500 | 0.0034242 | 0.0022013 | CFH/KYNU/FN1/COL7A1/LAMB2/CLDN16/ARHGAP24/GSN/CRB2/SAA1/WT1/PYGM/MMP1/FLT1/SLC7A7/MYO1E/MYOCD/APOL1/TBC1D8B/COL4A6/COL4A5 | 21 |
| HP_LOWER_EXTREMITY_JOINT_DISLOCATION | HP_LOWER_EXTREMITY_JOINT_DISLOCATION | HP_LOWER_EXTREMITY_JOINT_DISLOCATION | 33/1438 | 288/23056 | 0.1145833 | 1.837158 | 3.687190 | 0.0005584 | 0.0034752 | 0.0022341 | AGRN/HSPG2/TBX15/COL3A1/COL5A2/COL6A3/WNT5A/CD96/FGFRL1/ADAMTS2/RREB1/COL12A1/GJA1/GLI3/TMEM270/SHH/COLEC10/TPM2/GAS1/COL5A1/COL13A1/EFEMP2/ITGA7/ZIC2/SIX1/FBLN5/SMAD6/MYH8/COL1A1/SOX9/PIEZO2/COL6A2/GPC4 | 33 |
| BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_UP | 18/1438 | 122/23056 | 0.1475410 | 2.365581 | 3.900422 | 0.0005608 | 0.0034882 | 0.0022424 | CCN1/KYNU/FAP/GALNT3/MPP4/WWTR1/PDGFC/SPARC/IER3/OGFRL1/TBX18/SOD2/ANXA1/NACC2/DKK1/FOS/TMC8/TNFSF14 | 18 |
| GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 16/1438 | 102/23056 | 0.1568627 | 2.515040 | 3.955025 | 0.0005620 | 0.0034884 | 0.0022426 | RUNX3/ZC3H12A/NLRP3/TGFBR2/BCL6/LEF1/IL6/CD274/ANXA1/NCKAP1L/STAT6/IL4R/IL12RB1/BCL3/RELB/RUNX1 | 16 |
| GRADE_COLON_AND_RECTAL_CANCER_DN | GRADE_COLON_AND_RECTAL_CANCER_DN | GRADE_COLON_AND_RECTAL_CANCER_DN | 16/1438 | 102/23056 | 0.1568627 | 2.515040 | 3.955025 | 0.0005620 | 0.0034884 | 0.0022426 | SYNC/GFI1/ADAMTSL4/ITPKB/MITF/PLD1/CPN2/PLAC8/SASH1/PDK4/PTPRZ1/TRPS1/SIX1/LYPD3/LGALS2/COL4A5 | 16 |
| GOBP_HEART_FIELD_SPECIFICATION | GOBP_HEART_FIELD_SPECIFICATION | GOBP_HEART_FIELD_SPECIFICATION | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | WNT5A/EXT1/DKK1/BMP4/BMP2/GATA5 | 6 |
| GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | CSF1/RARRES2/C3AR1/THBS1/CCL5/C5AR1 | 6 |
| GOBP_REGULATION_OF_CARDIAC_MUSCLE_ADAPTATION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_ADAPTATION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_ADAPTATION | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | ERRFI1/ATP2B4/BMP10/PPARG/TRPC3/FOXO1 | 6 |
| GOBP_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE | GOBP_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE | GOBP_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | SRD5A2/EDN1/INHBA/PLAT/PAPPA/NOTCH1 | 6 |
| GOMF_CXCR_CHEMOKINE_RECEPTOR_BINDING | GOMF_CXCR_CHEMOKINE_RECEPTOR_BINDING | GOMF_CXCR_CHEMOKINE_RECEPTOR_BINDING | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2 | 6 |
| GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_BINDING | GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_BINDING | GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_BINDING | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | STAB1/CD36/MSR1/THBS1/CDH13/COLEC12 | 6 |
| HP_ABNORMALITY_OF_THE_MIDDLE_EAR_OSSICLES | HP_ABNORMALITY_OF_THE_MIDDLE_EAR_OSSICLES | HP_ABNORMALITY_OF_THE_MIDDLE_EAR_OSSICLES | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | TFAP2A/GDF6/SIX1/COL1A1/NOG/SIX5 | 6 |
| HP_PALMAR_HYPERHIDROSIS | HP_PALMAR_HYPERHIDROSIS | HP_PALMAR_HYPERHIDROSIS | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | LAMC2/LAMB3/PERP/KRT17/ITGB4/SERPINB7 | 6 |
| THUM_MIR21_TARGETS_HEART_DISEASE_UP | THUM_MIR21_TARGETS_HEART_DISEASE_UP | THUM_MIR21_TARGETS_HEART_DISEASE_UP | 6/1438 | 18/23056 | 0.3333333 | 5.344460 | 4.755585 | 0.0005636 | 0.0034884 | 0.0022426 | COL5A2/LUM/POSTN/LTBP2/COL1A1/BGN | 6 |
| GOBP_HUMORAL_IMMUNE_RESPONSE | GOBP_HUMORAL_IMMUNE_RESPONSE | GOBP_HUMORAL_IMMUNE_RESPONSE | 35/1438 | 312/23056 | 0.1121795 | 1.798616 | 3.662995 | 0.0005716 | 0.0035365 | 0.0022735 | CFH/PTPRC/IL1B/SPON2/JCHAIN/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/CFI/C9/HLA-E/TNFRSF21/IL6/RARRES2/CLU/COLEC10/IFNE/NOTCH1/ALOX5/MBL2/SFTPD/C1S/C1R/C1RL/PSMB10/CCR7/GATA6/ELANE/EBI3/C3/BCL3/WFDC10B | 35 |
| ZHENG_BOUND_BY_FOXP3 | ZHENG_BOUND_BY_FOXP3 | ZHENG_BOUND_BY_FOXP3 | 50/1438 | 496/23056 | 0.1008065 | 1.616268 | 3.578452 | 0.0005731 | 0.0035440 | 0.0022783 | S1PR1/CD53/PTPN22/HJV/PTPRC/NR5A2/ITGA6/SP100/TGFBR2/CD96/BCL6/TEC/SPP1/LEF1/INPP4B/IL7R/ADAMTS6/F2RL1/ADAM19/NT5E/PTPRK/TNFAIP3/CITED2/UTRN/UST/ZC3H12D/AHR/MDFIC/EXT1/TMEM71/ANXA1/APBB1IP/MAP3K8/NRP1/FAS/TRIM5/PRRG4/CD44/MS4A4A/UBASH3B/VWF/TESPA1/LATS2/FLT3/LCP1/FBLN5/GLDN/CCR7/KLF2/AXL | 50 |
| GOBP_RAS_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_RAS_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 38/1438 | 348/23056 | 0.1091954 | 1.750771 | 3.639671 | 0.0005752 | 0.0035551 | 0.0022855 | CSF1/TGFB2/ITPKB/RASGRP3/COL3A1/HEG1/PLD1/BCL6/ARHGAP24/PLK2/F2RL1/RREB1/MET/DOK2/GPR20/NOTCH1/NRP1/SYNPO2L/EPS8L2/ARHGAP42/APOC3/APOA1/ARHGDIB/EPS8/IGF1/PRKD1/LAT/CDH13/ITGA3/APOE/RRAS/CDC42EP5/RAC2/CYTH4/CDC42EP1/CELSR1/STARD8/LPAR4 | 38 |
| GOMF_PHOSPHATIDYLINOSITOL_4_5_BISPHOSPHATE_BINDING | GOMF_PHOSPHATIDYLINOSITOL_4_5_BISPHOSPHATE_BINDING | GOMF_PHOSPHATIDYLINOSITOL_4_5_BISPHOSPHATE_BINDING | 14/1438 | 83/23056 | 0.1686747 | 2.704426 | 4.012014 | 0.0005800 | 0.0035817 | 0.0023025 | LDLRAP1/CAPG/SCIN/GSDMD/GSN/ANXA8/SYTL2/ANXA2/GRAMD2A/ADAP2/KCNJ2/SDCBP2/JPH2/FRMPD4 | 14 |
| NGUYEN_NOTCH1_TARGETS_DN | NGUYEN_NOTCH1_TARGETS_DN | NGUYEN_NOTCH1_TARGETS_DN | 14/1438 | 83/23056 | 0.1686747 | 2.704426 | 4.012014 | 0.0005800 | 0.0035817 | 0.0023025 | CCN1/PTGS2/IL1R1/EPHA4/COL7A1/ITGA2/ELL2/TFAP2A/PSMB9/EXT1/KLF4/SERPINH1/MYO1E/GADD45B | 14 |
| GOBP_INOSITOL_PHOSPHATE_MEDIATED_SIGNALING | GOBP_INOSITOL_PHOSPHATE_MEDIATED_SIGNALING | GOBP_INOSITOL_PHOSPHATE_MEDIATED_SIGNALING | 11/1438 | 56/23056 | 0.1964286 | 3.149414 | 4.153406 | 0.0005905 | 0.0036415 | 0.0023410 | EDN2/ATP2B4/HRH1/MYOZ2/EDN1/ITPR3/MYOZ1/IGF1/NFATC4/PRNP/NFATC2 | 11 |
| HOQUE_METHYLATED_IN_CANCER | HOQUE_METHYLATED_IN_CANCER | HOQUE_METHYLATED_IN_CANCER | 11/1438 | 56/23056 | 0.1964286 | 3.149414 | 4.153406 | 0.0005905 | 0.0036415 | 0.0023410 | RUNX3/PTGS2/RARB/DAB2/TFAP2A/WT1/EDNRB/CDH13/SOCS3/BMP2/GATA5 | 11 |
| REACTOME_REGULATED_NECROSIS | REACTOME_REGULATED_NECROSIS | REACTOME_REGULATED_NECROSIS | 11/1438 | 56/23056 | 0.1964286 | 3.149414 | 4.153406 | 0.0005905 | 0.0036415 | 0.0023410 | IL1A/IL1B/CASP8/TNFRSF10A/GSDMD/FAS/BIRC3/CASP4/CASP1/MLKL/ELANE | 11 |
| GOBP_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY | 21/1438 | 154/23056 | 0.1363636 | 2.186370 | 3.809764 | 0.0006002 | 0.0036997 | 0.0023784 | TNFSF18/RAB7B/AGT/NLRP3/IL1B/IRAK2/WNT5A/IL1RAP/TLR3/TRIML2/TRIML1/TRIM38/IL6/CD36/CAV1/CLU/TRAF1/TRIM5/CARD16/PRKD1/TNFRSF11A | 21 |
| HP_MICRODONTIA | HP_MICRODONTIA | HP_MICRODONTIA | 19/1438 | 133/23056 | 0.1428571 | 2.290483 | 3.849431 | 0.0006016 | 0.0037033 | 0.0023807 | LAMB3/TGFA/COL3A1/TWIST2/FGFR3/FOXC1/TFAP2A/GJA1/FAM20C/TMEM270/TRPS1/FGFR2/C1S/C1R/WNT10B/GLI1/PRKD1/SIX1/DLX3 | 19 |
| QI_HYPOXIA | QI_HYPOXIA | QI_HYPOXIA | 19/1438 | 133/23056 | 0.1428571 | 2.290483 | 3.849431 | 0.0006016 | 0.0037033 | 0.0023807 | BHLHE40/IRX2/IER3/CD109/COL12A1/FZD1/STC1/PLEKHA2/PPP1R3C/ADM/CRYAB/ITGA11/MT1X/KRT19/SOX9/TNFSF9/HMOX1/KDELR3/IL13RA1 | 19 |
| ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | 19/1438 | 133/23056 | 0.1428571 | 2.290483 | 3.849431 | 0.0006016 | 0.0037033 | 0.0023807 | AGRN/FUCA1/TINAGL1/VCAM1/ECM1/CAPG/FN1/SPP1/PPIC/SPARC/SEMA3C/CLU/VCL/MSLN/COL1A1/SDC4/COL18A1/MSN/BGN | 19 |
| GOBP_CELLULAR_EXTRAVASATION | GOBP_CELLULAR_EXTRAVASATION | GOBP_CELLULAR_EXTRAVASATION | 13/1438 | 74/23056 | 0.1756757 | 2.816675 | 4.036950 | 0.0006043 | 0.0037160 | 0.0023889 | VCAM1/IL1R1/ITGA4/TRIM55/EXT1/SELPLG/PECAM1/ELANE/ICAM1/IL27RA/PLVAP/SIRPA/XG | 13 |
| RAMALHO_STEMNESS_DN | RAMALHO_STEMNESS_DN | RAMALHO_STEMNESS_DN | 13/1438 | 74/23056 | 0.1756757 | 2.816675 | 4.036950 | 0.0006043 | 0.0037160 | 0.0023889 | CD53/CTSS/PTPRC/HSD11B1/GYPA/CEBPD/GSN/NRP1/PAPSS2/HBD/CD68/ADGRE1/SIRPA | 13 |
| HP_FATIGUE | HP_FATIGUE | HP_FATIGUE | 39/1438 | 361/23056 | 0.1080332 | 1.732138 | 3.616061 | 0.0006044 | 0.0037160 | 0.0023889 | PTPN22/CFH/NLRP3/COL5A2/NABP1/EPHA4/TGFBR2/BCL6/SLC34A2/CFI/TLR3/HFE/CITED2/PON3/SLC26A4/MET/PODXL/TPM2/PTPN3/TNFSF15/COL5A1/FAS/NFKB2/PYGM/BIRC3/SCNN1A/ITGA7/STAT6/PYGL/SERPINA6/ACTC1/PIEZO1/COL1A1/GATA6/ELANE/IL12RB1/KCNN4/COL9A3/RUNX1 | 39 |
| GOBP_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | GOBP_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 35/1438 | 313/23056 | 0.1118211 | 1.792870 | 3.642541 | 0.0006060 | 0.0037236 | 0.0023938 | MCOLN2/CASQ1/PTPRC/ATP2B4/TMEM37/TRPM8/TRPC3/EDN1/ITPR3/TRDN/PKD1L1/TRPA1/TMC1/TRPM6/AHNAK/CATSPER1/UBASH3B/CACNA2D4/TPCN1/TRPC4/EDNRB/PRKD1/SLC24A4/BDKRB1/ANXA2/ORAI3/RRAD/TRPV2/CCR7/HAP1/CACNA1A/CACNG6/PRNP/REM1/JPH2 | 35 |
| GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | 12/1438 | 65/23056 | 0.1846154 | 2.960009 | 4.081220 | 0.0006105 | 0.0037483 | 0.0024096 | PTCH2/GDNF/FOXC1/BMP6/SERPINE1/NOTCH1/PLAAT4/WNT10B/BMP4/LHX1/SOX9/LIF | 12 |
| GOBP_REGULATION_OF_EPIDERMIS_DEVELOPMENT | GOBP_REGULATION_OF_EPIDERMIS_DEVELOPMENT | GOBP_REGULATION_OF_EPIDERMIS_DEVELOPMENT | 12/1438 | 65/23056 | 0.1846154 | 2.960009 | 4.081220 | 0.0006105 | 0.0037483 | 0.0024096 | ERRFI1/PTCH2/HES1/FOXC1/CD109/HOXA7/AQP3/NOTCH1/PLAAT4/BMP4/ZFP36L1/ZFP36 | 12 |
| WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN | 15/1438 | 93/23056 | 0.1612903 | 2.586029 | 3.952688 | 0.0006123 | 0.0037573 | 0.0024154 | AGRN/CAPG/COL3A1/COL5A2/COL6A3/MICB/THBS2/ANXA1/CASP4/LUM/NID2/DSG2/SIM2/RAC2/LGALS1 | 15 |
| GOBP_AORTIC_VALVE_MORPHOGENESIS | GOBP_AORTIC_VALVE_MORPHOGENESIS | GOBP_AORTIC_VALVE_MORPHOGENESIS | 8/1438 | 32/23056 | 0.2500000 | 4.008345 | 4.392042 | 0.0006133 | 0.0037573 | 0.0024154 | TIE1/SLIT2/NOTCH1/BMP4/SMAD6/SOX9/TGFB1/GATA5 | 8 |
| GOBP_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | 8/1438 | 32/23056 | 0.2500000 | 4.008345 | 4.392042 | 0.0006133 | 0.0037573 | 0.0024154 | CSF1/AGT/PPARG/CSF2/CD36/MSR1/NFKBIA/CETP | 8 |
| GOMF_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_BINDING | GOMF_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_BINDING | GOMF_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_BINDING | 8/1438 | 32/23056 | 0.2500000 | 4.008345 | 4.392042 | 0.0006133 | 0.0037573 | 0.0024154 | EFEMP1/TGFA/EPGN/EREG/BTC/EGF/HBEGF/ITGA5 | 8 |
| HP_LIMITATION_OF_NECK_MOTION | HP_LIMITATION_OF_NECK_MOTION | HP_LIMITATION_OF_NECK_MOTION | 8/1438 | 32/23056 | 0.2500000 | 4.008345 | 4.392042 | 0.0006133 | 0.0037573 | 0.0024154 | TLR3/GDF6/DKK1/MEOX1/NOG/CACNA1A/SCN1B/COL6A2 | 8 |
| GOMF_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 49/1438 | 485/23056 | 0.1010309 | 1.619867 | 3.558348 | 0.0006160 | 0.0037718 | 0.0024247 | MCOLN2/KCNN3/TMEM63A/TMEM37/KCNE4/TRPM8/GRID2/TRPC3/ITPR3/CLIC5/RHAG/GJA1/AQP1/PKD1L1/TRPA1/SLC26A7/AQP7/AQP3/TMC1/TRPM6/CLIC3/LRRC55/CATSPER1/CACNA2D4/KCNA5/SCNN1A/KCNH3/BEST3/TPCN1/TRPC4/SLC24A4/ANXA2/HCN4/ORAI3/PIEZO1/TRPV2/KCNJ2/TMC8/PIEZO2/SLC14A1/CACNA1A/SCN1B/KCNK6/KCNN4/KCNA7/CACNG6/CLIC6/APOL1/GABRE | 49 |
| GOBP_REGULATION_OF_SYNAPSE_ASSEMBLY | GOBP_REGULATION_OF_SYNAPSE_ASSEMBLY | GOBP_REGULATION_OF_SYNAPSE_ASSEMBLY | 16/1438 | 103/23056 | 0.1553398 | 2.490622 | 3.910395 | 0.0006275 | 0.0038407 | 0.0024691 | AGRN/WNT5A/IL1RAP/GRID2/MDGA1/TPBG/THBS2/FZD1/DKK1/AMIGO2/LRFN5/SIX1/SIX4/SRPX2/GPC4/SLITRK4 | 16 |
| HP_WADDLING_GAIT | HP_WADDLING_GAIT | HP_WADDLING_GAIT | 17/1438 | 113/23056 | 0.1504425 | 2.412101 | 3.880916 | 0.0006289 | 0.0038473 | 0.0024733 | AGRN/FN1/COL6A3/LAMB2/DOK7/COL12A1/LAMA2/FLNC/TPM2/MYPN/COL13A1/MYH2/SGCA/NOG/TGFB1/COL9A3/COL6A2 | 17 |
| BENPORATH_OCT4_TARGETS | BENPORATH_OCT4_TARGETS | BENPORATH_OCT4_TARGETS | 33/1438 | 290/23056 | 0.1137931 | 1.824488 | 3.644133 | 0.0006307 | 0.0038567 | 0.0024793 | DHRS3/OLFML3/IFI16/OSR1/KDR/GRID2/IRX2/SMIM3/B3GALT4/COL12A1/LAMA4/GJA1/CCN2/THBS2/SULF1/MSC/TRPS1/HAS2/GAS1/DKK1/ANKRD1/HHEX/FGFR2/H2AJ/AMIGO2/FOXO1/ZIC2/ZFP36L1/SALL1/MMP2/JUP/GATA6/KLHL4 | 33 |
| BROWNE_HCMV_INFECTION_2HR_DN | BROWNE_HCMV_INFECTION_2HR_DN | BROWNE_HCMV_INFECTION_2HR_DN | 10/1438 | 48/23056 | 0.2083333 | 3.340287 | 4.186052 | 0.0006384 | 0.0038918 | 0.0025019 | ITGA6/ITGA2/SERPINE1/TPM2/COL13A1/MMP3/ANXA2/KRT19/ITGA3/AXL | 10 |
| GOBP_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | GOBP_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | GOBP_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | 10/1438 | 48/23056 | 0.2083333 | 3.340287 | 4.186052 | 0.0006384 | 0.0038918 | 0.0025019 | HJV/BMP10/TGFBR2/FST/CITED2/INHBA/SHH/GDF6/DACT1/FSTL3 | 10 |
| GOBP_VASODILATION | GOBP_VASODILATION | GOBP_VASODILATION | 10/1438 | 48/23056 | 0.2083333 | 3.340287 | 4.186052 | 0.0006384 | 0.0038918 | 0.0025019 | AGT/CPS1/NPR3/F2RL1/ADRB2/SOD2/EXT1/EDNRB/KLF2/APOE | 10 |
| HP_ABNORMAL_RIGHT_VENTRICLE_MORPHOLOGY | HP_ABNORMAL_RIGHT_VENTRICLE_MORPHOLOGY | HP_ABNORMAL_RIGHT_VENTRICLE_MORPHOLOGY | 10/1438 | 48/23056 | 0.2083333 | 3.340287 | 4.186052 | 0.0006384 | 0.0038918 | 0.0025019 | FCGR2A/LAMB2/CITED2/TPM2/NOTCH1/ITGA7/ACTC1/FOXF1/GATA6/TGFB1 | 10 |
| HP_ABNORMALITY_OF_THE_AXILLARY_HAIR | HP_ABNORMALITY_OF_THE_AXILLARY_HAIR | HP_ABNORMALITY_OF_THE_AXILLARY_HAIR | 10/1438 | 48/23056 | 0.2083333 | 3.340287 | 4.186052 | 0.0006384 | 0.0038918 | 0.0025019 | CCDC141/ADAMTS3/FAT4/PSMB8/ZFPM2/WT1/SOX9/ITGB4/AXL/APOE | 10 |
| PARK_APL_PATHOGENESIS_DN | PARK_APL_PATHOGENESIS_DN | PARK_APL_PATHOGENESIS_DN | 10/1438 | 48/23056 | 0.2083333 | 3.340287 | 4.186052 | 0.0006384 | 0.0038918 | 0.0025019 | CXCL8/GPNMB/ZYX/SRGN/IL32/CES1/PECAM1/SERPINB2/ELANE/SIRPA | 10 |
| REACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS | REACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS | REACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS | 10/1438 | 48/23056 | 0.2083333 | 3.340287 | 4.186052 | 0.0006384 | 0.0038918 | 0.0025019 | AGRN/HSPG2/AKR1B10/AKR1C3/APOC3/APOA1/LRP10/APOE/SDC4/GPC4 | 10 |
| BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP | BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP | BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_UP | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | CCN1/SEMA3A/MYOF/HTRA1/IGF1/MT2A/MT1X | 7 |
| GOBP_ACUTE_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | GOBP_ACUTE_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | GOBP_ACUTE_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | IL31RA/HLA-E/EXT1/NLRP6/CCR7/ELANE/C3 | 7 |
| GOBP_MEMBRANE_RAFT_ORGANIZATION | GOBP_MEMBRANE_RAFT_ORGANIZATION | GOBP_MEMBRANE_RAFT_ORGANIZATION | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | S100A10/PTPRC/DOCK2/CAV2/CAV1/GSN/ANXA2 | 7 |
| GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_MIGRATION | GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_MIGRATION | GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_MIGRATION | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | CSF1/RARRES2/C3AR1/MMP14/THBS1/CCL5/C5AR1 | 7 |
| LU_TUMOR_ANGIOGENESIS_UP | LU_TUMOR_ANGIOGENESIS_UP | LU_TUMOR_ANGIOGENESIS_UP | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | SPP1/FGF18/EDN1/PDGFA/STC1/NOTCH1/CD44 | 7 |
| MATZUK_SPERMATOGONIA | MATZUK_SPERMATOGONIA | MATZUK_SPERMATOGONIA | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | CSF1/GDNF/ADAMTS2/GJA1/STRA8/CYP19A1/DNMT3L | 7 |
| PID_INTEGRIN_A9B1_PATHWAY | PID_INTEGRIN_A9B1_PATHWAY | PID_INTEGRIN_A9B1_PATHWAY | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | VCAM1/FN1/SPP1/VEGFC/CSF2/TGM2/SAT1 | 7 |
| WP_IL1_AND_MEGAKARYOCYTES_IN_OBESITY | WP_IL1_AND_MEGAKARYOCYTES_IN_OBESITY | WP_IL1_AND_MEGAKARYOCYTES_IN_OBESITY | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | NLRP3/IL1R1/IL1B/CCR3/HBEGF/PLA2G7/ICAM1 | 7 |
| XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR | XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR | XU_HGF_SIGNALING_NOT_VIA_AKT1_6HR | 7/1438 | 25/23056 | 0.2800000 | 4.489346 | 4.502067 | 0.0006421 | 0.0038988 | 0.0025064 | HBEGF/PLAU/DNMBP/PHLDA2/CD44/NAV3/SAT1 | 7 |
| GOBP_ENDOCARDIAL_CUSHION_MORPHOGENESIS | GOBP_ENDOCARDIAL_CUSHION_MORPHOGENESIS | GOBP_ENDOCARDIAL_CUSHION_MORPHOGENESIS | 9/1438 | 40/23056 | 0.2250000 | 3.607510 | 4.256919 | 0.0006541 | 0.0039638 | 0.0025482 | TGFB2/TGFBR2/NOTCH1/BMP4/NOG/SOX9/TGFB1/BMP2/GATA5 | 9 |
| GOBP_POSITIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY | 9/1438 | 40/23056 | 0.2250000 | 3.607510 | 4.256919 | 0.0006541 | 0.0039638 | 0.0025482 | CCN1/HES1/KDR/FOXD1/SULF1/CRB2/NOTCH1/BMP4/GATA6 | 9 |
| HP_ABNORMAL_CIRCULATING_IGE_LEVEL | HP_ABNORMAL_CIRCULATING_IGE_LEVEL | HP_ABNORMAL_CIRCULATING_IGE_LEVEL | 9/1438 | 40/23056 | 0.2250000 | 3.607510 | 4.256919 | 0.0006541 | 0.0039638 | 0.0025482 | CASP10/COL7A1/IL7R/PLA2G7/FAS/NCKAP1L/IL4R/TGFB1/GPC4 | 9 |
| WP_INTERACTIONS_BETWEEN_IMMUNE_CELLS_AND_MICRORNAS_IN_TUMOR_MICROENVIRONMENT | WP_INTERACTIONS_BETWEEN_IMMUNE_CELLS_AND_MICRORNAS_IN_TUMOR_MICROENVIRONMENT | WP_INTERACTIONS_BETWEEN_IMMUNE_CELLS_AND_MICRORNAS_IN_TUMOR_MICROENVIRONMENT | 9/1438 | 40/23056 | 0.2250000 | 3.607510 | 4.256919 | 0.0006541 | 0.0039638 | 0.0025482 | TGFB2/TGFBR2/CD274/NFKB2/STAT6/IL4R/CCL5/TGFB1/IL2RB | 9 |
| KEGG_JAK_STAT_SIGNALING_PATHWAY | KEGG_JAK_STAT_SIGNALING_PATHWAY | KEGG_JAK_STAT_SIGNALING_PATHWAY | 21/1438 | 155/23056 | 0.1354839 | 2.172264 | 3.776752 | 0.0006543 | 0.0039638 | 0.0025482 | IL22RA1/IL15/IL7R/OSMR/TSLP/CSF2/IL6/IFNE/IL15RA/STAT6/IRF9/IL4R/IL21R/CTF1/CSF3/SOCS3/IL12RB1/IL11/LIF/IL2RB/IL13RA1 | 21 |
| GOBP_RESPONSE_TO_PURINE_CONTAINING_COMPOUND | GOBP_RESPONSE_TO_PURINE_CONTAINING_COMPOUND | GOBP_RESPONSE_TO_PURINE_CONTAINING_COMPOUND | 19/1438 | 134/23056 | 0.1417910 | 2.273390 | 3.812780 | 0.0006608 | 0.0040015 | 0.0025724 | PTGS2/IL1B/CPS1/TRPC3/CRHBP/AHR/AQP1/STC1/PLAT/WT1/FOSL1/P2RY2/WNT10B/ZFP36L1/FOS/HCN4/COL1A1/GATA6/THBD | 19 |
| HP_DECREASED_CIRCULATING_ANTIBODY_LEVEL | HP_DECREASED_CIRCULATING_ANTIBODY_LEVEL | HP_DECREASED_CIRCULATING_ANTIBODY_LEVEL | 23/1438 | 177/23056 | 0.1299435 | 2.083433 | 3.731854 | 0.0006742 | 0.0040811 | 0.0026236 | CASP10/CASP8/SP110/ADAMTS3/FAT4/HFE/STX11/SAMD9L/FAS/NFKB2/SLC7A7/SERPINA1/IL21R/LAT/CAVIN1/TNFRSF11A/CD70/PLVAP/TGFB1/KCNN4/HMOX1/RAC2/MSN | 23 |
| MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | 45/1438 | 437/23056 | 0.1029748 | 1.651034 | 3.543744 | 0.0006779 | 0.0041017 | 0.0026368 | HTR1D/SCTR/SLIT2/SLC34A2/FGF5/NKD2/IRX4/GDNF/ITGA2/TGFBI/ABLIM3/SLC6A7/ADAMTS2/BMP6/TDRD6/SHH/PDLIM2/FIBCD1/COL13A1/HTR7/TCERG1L/CCKBR/P4HA3/WNT10B/KRT7/GRIP1/NPAS3/CYP46A1/LTK/PAQR5/ALDH1A3/RRAD/ADAMTS18/FOXF1/CLDN7/NOG/SLC7A10/BMP2/PTGIS/CYP24A1/GATA5/SIM2/DNMT3L/ELFN2/WNT7B | 45 |
| REACTOME_MAPK_FAMILY_SIGNALING_CASCADES | REACTOME_MAPK_FAMILY_SIGNALING_CASCADES | REACTOME_MAPK_FAMILY_SIGNALING_CASCADES | 36/1438 | 327/23056 | 0.1100917 | 1.765143 | 3.594019 | 0.0006814 | 0.0041206 | 0.0026490 | PTPN7/RASGRP3/TGFA/FN1/FGFR3/EPGN/EREG/BTC/FGF5/EGF/GDNF/CSF2/HBEGF/FGF18/PSMB8/PSMB9/PDGFA/IL6/MET/FGF20/ANGPT1/TEK/PTPN3/APBB1IP/VCL/FGFR2/MMP10/VWF/FLT3/FOXO1/LAT/MMP2/PSMB10/CDC42EP5/IL2RB/PDGFB | 36 |
| GOBP_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | GOBP_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | GOBP_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS | 13/1438 | 75/23056 | 0.1733333 | 2.779119 | 3.980205 | 0.0006899 | 0.0041685 | 0.0026798 | IL36G/IL31RA/PLK2/HLA-E/EXT1/NOTCH1/NLRP6/CD68/CCR7/RHBDF2/ELANE/C3/CYSLTR1 | 13 |
| REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING | REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING | REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING | 13/1438 | 75/23056 | 0.1733333 | 2.779119 | 3.980205 | 0.0006899 | 0.0041685 | 0.0026798 | TGFA/EPGN/EREG/BTC/EGF/HBEGF/CAV2/CAV1/S1PR3/MMP3/FOS/MMP2/GNGT2 | 13 |
| GOBP_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | GOBP_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | GOBP_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | 11/1438 | 57/23056 | 0.1929825 | 3.094161 | 4.082698 | 0.0006910 | 0.0041698 | 0.0026806 | WNT5A/PRICKLE2/DAB2/RSPO3/FZD1/FZD6/CTHRC1/DKK1/DACT1/CELSR1/GPC4 | 11 |
| GOBP_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY | GOBP_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY | GOBP_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY | 11/1438 | 57/23056 | 0.1929825 | 3.094161 | 4.082698 | 0.0006910 | 0.0041698 | 0.0026806 | FGFR3/TEK/CCKBR/FLT3/FLT1/PRKD1/TNFAIP8L3/CCR7/SOCS3/TGFB1/PDGFB | 11 |
| GOMF_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING | GOMF_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING | GOMF_CALCIUM_DEPENDENT_PHOSPHOLIPID_BINDING | 11/1438 | 57/23056 | 0.1929825 | 3.094161 | 4.082698 | 0.0006910 | 0.0041698 | 0.0026806 | PLA2G4A/ESYT3/ANXA3/ANXA13/ANXA1/ANXA8L1/ANXA8/SYT12/PLA2G4D/ANXA2/PLA2G4C | 11 |
| GOBP_POSITIVE_REGULATION_OF_NEUROGENESIS | GOBP_POSITIVE_REGULATION_OF_NEUROGENESIS | GOBP_POSITIVE_REGULATION_OF_NEUROGENESIS | 27/1438 | 222/23056 | 0.1216216 | 1.950006 | 3.668309 | 0.0006933 | 0.0041817 | 0.0026883 | TNFRSF1B/CRABP2/IL1B/FN1/EPHA4/SERPINE2/MME/HES1/SLIT2/VEGFC/SEMA5A/IL6/GLI3/PTPRZ1/PTN/SHH/PLAG1/NOTCH1/NRP1/SOX8/TRPV2/HAP1/MAG/TGFB1/BMP2/TGM2/LIF | 27 |
| HP_MULTICYSTIC_KIDNEY_DYSPLASIA | HP_MULTICYSTIC_KIDNEY_DYSPLASIA | HP_MULTICYSTIC_KIDNEY_DYSPLASIA | 17/1438 | 114/23056 | 0.1491228 | 2.390943 | 3.839726 | 0.0006970 | 0.0042020 | 0.0027013 | LAMC2/LMOD1/LAMB3/ACTG2/CD96/MYLK/TFAP2A/TBX18/RSPO2/GRIP1/FREM2/SIX1/SALL1/LHX1/PIEZO2/SIX5/GPC4 | 17 |
| GOCC_CELL_PROJECTION_MEMBRANE | GOCC_CELL_PROJECTION_MEMBRANE | GOCC_CELL_PROJECTION_MEMBRANE | 37/1438 | 340/23056 | 0.1088235 | 1.744809 | 3.568393 | 0.0007188 | 0.0043316 | 0.0027846 | DHRS3/EPHA2/DPP4/FAP/CYBRD1/SLC34A2/ABCG2/SLC7A11/MYO10/UTRN/AQP1/PKD1L1/CD36/SLC26A4/PODXL/ATP6V0A4/DDX58/B4GALT1/TRPM6/AIF1L/ITGA8/JCAD/EPS8L2/CD44/PTPRJ/SCNN1A/EPS8/ITGA5/LCP1/PLEK2/TPM1/CSPG4/SLC28A1/PIEZO1/ITGA3/MSN/GABRE | 37 |
| GOMF_CALMODULIN_BINDING | GOMF_CALMODULIN_BINDING | GOMF_CALMODULIN_BINDING | 25/1438 | 200/23056 | 0.1250000 | 2.004173 | 3.678557 | 0.0007206 | 0.0043404 | 0.0027903 | KCNN3/ATP2B4/CAMK1G/ITPKB/CFAP221/MYLK/MYO10/IQGAP2/PDE1C/ADCY8/FAS/SLC24A4/MYO1E/RRAD/MYH13/MYH8/MYH4/MYH1/MYH2/MBP/CNN2/CNN1/KCNN4/REM1/MYH9 | 25 |
| TSENG_IRS1_TARGETS_DN | TSENG_IRS1_TARGETS_DN | TSENG_IRS1_TARGETS_DN | 19/1438 | 135/23056 | 0.1407407 | 2.256550 | 3.776453 | 0.0007250 | 0.0043651 | 0.0028061 | IL1R1/COL3A1/COL6A3/TNNC1/DAB2/TGFBI/TAPBP/GJA1/EPHB6/FABP4/NRP1/ADM/MMP14/FRMD6/SIX1/ACTC1/SMAD6/MYL4/THBD | 19 |
| REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | 24/1438 | 189/23056 | 0.1269841 | 2.035985 | 3.688365 | 0.0007278 | 0.0043802 | 0.0028159 | AGRN/HSPG2/PTGS2/AOX1/PARP14/ALDH1L1/NT5E/VNN1/VNN2/AKR1B10/TPK1/PARP10/AKR1C3/RNLS/NNMT/APOC3/APOA1/LRP10/CTRB1/MOCOS/APOE/SDC4/PTGIS/GPC4 | 24 |
| GOBP_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | 14/1438 | 85/23056 | 0.1647059 | 2.640792 | 3.908654 | 0.0007418 | 0.0044588 | 0.0028664 | ITPKB/WNT5A/BCL6/SLC7A11/IL7R/IDO1/ST3GAL1/CD274/ANXA1/BMP4/CCL5/CCR7/AXL/BIRC7 | 14 |
| GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY | GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY | GOBP_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY | 14/1438 | 85/23056 | 0.1647059 | 2.640792 | 3.908654 | 0.0007418 | 0.0044588 | 0.0028664 | MR1/PTPRC/CXCL6/IL7R/F2RL1/HLA-E/MICA/RAET1E/KLRD1/KLRC4-KLRK1/NCKAP1L/ICAM1/IL12RB1/NECTIN2 | 14 |
| SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | 14/1438 | 85/23056 | 0.1647059 | 2.640792 | 3.908654 | 0.0007418 | 0.0044588 | 0.0028664 | PDZK1IP1/ACTG2/MLPH/TM4SF1/PLK2/PERP/CADPS2/ATP6V0A4/CEBPD/MMP10/SCNN1A/SERPINA1/GDF15/CELSR1 | 14 |
| CROMER_TUMORIGENESIS_DN | CROMER_TUMORIGENESIS_DN | CROMER_TUMORIGENESIS_DN | 10/1438 | 49/23056 | 0.2040816 | 3.272118 | 4.106324 | 0.0007579 | 0.0045433 | 0.0029207 | ECM1/PTN/CLU/AQP3/EMP1/KRT4/MYH2/KRT13/KRT15/ZNF185 | 10 |
| GOBP_DIGESTIVE_TRACT_MORPHOGENESIS | GOBP_DIGESTIVE_TRACT_MORPHOGENESIS | GOBP_DIGESTIVE_TRACT_MORPHOGENESIS | 10/1438 | 49/23056 | 0.2040816 | 3.272118 | 4.106324 | 0.0007579 | 0.0045433 | 0.0029207 | WNT5A/GLI3/SHH/NOTCH1/FGFR2/GLI1/BMP4/DACT1/RBPMS2/FOXF1 | 10 |
| GOBP_PROGRAMMED_NECROTIC_CELL_DEATH | GOBP_PROGRAMMED_NECROTIC_CELL_DEATH | GOBP_PROGRAMMED_NECROTIC_CELL_DEATH | 10/1438 | 49/23056 | 0.2040816 | 3.272118 | 4.106324 | 0.0007579 | 0.0045433 | 0.0029207 | CASP8/TLR3/CAV1/FAS/NLRP6/BIRC3/YBX3/PYGL/NUPR1/MLKL | 10 |
| GOBP_REGULATION_OF_BONE_REMODELING | GOBP_REGULATION_OF_BONE_REMODELING | GOBP_REGULATION_OF_BONE_REMODELING | 10/1438 | 49/23056 | 0.2040816 | 3.272118 | 4.106324 | 0.0007579 | 0.0045433 | 0.0029207 | S1PR1/SPP1/GJA1/TNFAIP3/IL6/PDK4/TNFRSF11B/UBASH3B/SIGLEC15/TNFRSF11A | 10 |
| GOBP_T_CELL_SELECTION | GOBP_T_CELL_SELECTION | GOBP_T_CELL_SELECTION | 10/1438 | 49/23056 | 0.2040816 | 3.272118 | 4.106324 | 0.0007579 | 0.0045433 | 0.0029207 | PTPRC/ITPKB/IL15/DOCK2/IL6/GLI3/SHH/STAT6/CCR7/IL12RB1 | 10 |
| GUILLAUMOND_KLF10_TARGETS_UP | GUILLAUMOND_KLF10_TARGETS_UP | GUILLAUMOND_KLF10_TARGETS_UP | 10/1438 | 49/23056 | 0.2040816 | 3.272118 | 4.106324 | 0.0007579 | 0.0045433 | 0.0029207 | ITGA4/SERPINE2/MOXD1/CCKBR/SAA1/NNMT/ADAMTS8/MT1X/TFAP2C/IL2RB | 10 |
| HP_ABNORMALITY_OF_TEMPERATURE_REGULATION | HP_ABNORMALITY_OF_TEMPERATURE_REGULATION | HP_ABNORMALITY_OF_TEMPERATURE_REGULATION | 48/1438 | 477/23056 | 0.1006289 | 1.613422 | 3.491567 | 0.0007590 | 0.0045477 | 0.0029236 | HSPG2/GFI1/PTPN22/LAMC2/CFH/LAMB3/NLRP3/GYPC/NABP1/IL17RC/BCL6/SLC34A2/ARHGAP24/SPP1/TLR3/IL7R/STING1/PSMB8/PSMB9/TNFAIP3/STX11/IL6/SHH/GAS1/PTPN3/CRB2/FAS/WT1/BIRC3/TNFRSF1A/SCNN1A/KRT8/KRT18/STAT6/ZIC2/NFKBIA/EPB42/MYO1E/PSMB10/COL1A1/ELANE/CD70/CACNA1A/PRNP/RUNX1/APOL1/IL2RB/TBC1D8B | 48 |
| MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | 46/1438 | 452/23056 | 0.1017699 | 1.631716 | 3.498263 | 0.0007635 | 0.0045688 | 0.0029372 | IFI44L/FRRS1/VCAM1/CCDC141/CAVIN2/AOX1/LAMB2/PLD1/SLC7A11/CTSO/ADAMTS12/RAI14/ADAMTS6/SPARC/ARHGAP18/SYNJ2/PDE1C/SEMA3A/ASB15/AKR1B10/PTN/STC1/TCIM/PLAT/CA3/SLC26A7/ANGPT1/CD274/FAS/IFITM2/CD44/EMP1/NAV3/CBLN3/NQO1/COL1A1/ABCA8/ABCA9/KCNJ2/HSPB6/AXL/RIN2/NDP/LPAR4/ITM2A/COL4A5 | 46 |
| AMIT_SERUM_RESPONSE_40_MCF10A | AMIT_SERUM_RESPONSE_40_MCF10A | AMIT_SERUM_RESPONSE_40_MCF10A | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | IL1A/CXCL3/CXCL2/CITED2/ADM/FOS/ZFP36/FPR1 | 8 |
| FRIDMAN_IMMORTALIZATION_DN | FRIDMAN_IMMORTALIZATION_DN | FRIDMAN_IMMORTALIZATION_DN | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | IFI16/SPARC/CCN2/AHR/SERPINE1/HTRA1/IGFBP6/ALDH1A3 | 8 |
| HP_VERTEBRAL_COMPRESSION_FRACTURE | HP_VERTEBRAL_COMPRESSION_FRACTURE | HP_VERTEBRAL_COMPRESSION_FRACTURE | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | SPARC/TENT5A/DKK1/CREB3L1/SERPINH1/MMP2/TNFRSF11A/PLS3 | 8 |
| KASLER_HDAC7_TARGETS_2_DN | KASLER_HDAC7_TARGETS_2_DN | KASLER_HDAC7_TARGETS_2_DN | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | BHLHE40/MDGA1/ZCCHC24/IFITM2/TNFRSF19/NFKBIA/GADD45B/KLF2 | 8 |
| PID_INTEGRIN_A4B1_PATHWAY | PID_INTEGRIN_A4B1_PATHWAY | PID_INTEGRIN_A4B1_PATHWAY | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | VCAM1/ITGA4/FN1/SPP1/THBS2/ADAM28/THBS1/MYH2 | 8 |
| PID_SYNDECAN_2_PATHWAY | PID_SYNDECAN_2_PATHWAY | PID_SYNDECAN_2_PATHWAY | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | FN1/CXCL8/ITGA2/CSF2/CAV2/ITGA5/MMP2/TGFB1 | 8 |
| REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES | REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES | REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | MMP10/MMP1/MMP3/MMP14/MMP2/CTRB1/ELANE/COL18A1 | 8 |
| WP_TYPE_I_COLLAGEN_SYNTHESIS_IN_THE_CONTEXT_OF_OSTEOGENESIS_IMPERFECTA | WP_TYPE_I_COLLAGEN_SYNTHESIS_IN_THE_CONTEXT_OF_OSTEOGENESIS_IMPERFECTA | WP_TYPE_I_COLLAGEN_SYNTHESIS_IN_THE_CONTEXT_OF_OSTEOGENESIS_IMPERFECTA | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | P3H2/ADAMTS2/FZD1/TNFRSF11B/CREB3L1/SERPINH1/COL1A1/TNFRSF11A | 8 |
| ZHAN_LATE_DIFFERENTIATION_GENES_UP | ZHAN_LATE_DIFFERENTIATION_GENES_UP | ZHAN_LATE_DIFFERENTIATION_GENES_UP | 8/1438 | 33/23056 | 0.2424242 | 3.886880 | 4.280150 | 0.0007658 | 0.0045688 | 0.0029372 | ITGA4/BMP6/CAV2/CAV1/IGF1/SELPLG/PECAM1/EMP3 | 8 |
| GOBP_POSITIVE_REGULATION_OF_JNK_CASCADE | GOBP_POSITIVE_REGULATION_OF_JNK_CASCADE | GOBP_POSITIVE_REGULATION_OF_JNK_CASCADE | 15/1438 | 95/23056 | 0.1578947 | 2.531586 | 3.857999 | 0.0007699 | 0.0045894 | 0.0029504 | IL1A/IL1B/WNT5A/TLR3/F2RL1/SH3RF2/TPD52L1/CCN2/SEMA3A/TRAF1/TNFRSF19/CCR7/GADD45B/BIRC7/WNT7B | 15 |
| GOMF_MODIFIED_AMINO_ACID_BINDING | GOMF_MODIFIED_AMINO_ACID_BINDING | GOMF_MODIFIED_AMINO_ACID_BINDING | 15/1438 | 95/23056 | 0.1578947 | 2.531586 | 3.857999 | 0.0007699 | 0.0045894 | 0.0029504 | RPE65/CAVIN2/CPS1/OSBPL10/MME/SCIN/ANXA13/GSDMD/SYT12/SYTL2/THBS1/ANXA2/MFGE8/AXL/JPH2 | 15 |
| HP_AIRWAY_OBSTRUCTION | HP_AIRWAY_OBSTRUCTION | HP_AIRWAY_OBSTRUCTION | 17/1438 | 115/23056 | 0.1478261 | 2.370152 | 3.798968 | 0.0007713 | 0.0045934 | 0.0029530 | PTPN22/CFAP221/FGFR3/DNAH5/MCIDAS/CCNO/RREB1/CITED2/FGFR2/MMP1/SCNN1A/SERPINA1/ACTC1/SOX9/GATA6/HMOX1/RAC2 | 17 |
| LAIHO_COLORECTAL_CANCER_SERRATED_UP | LAIHO_COLORECTAL_CANCER_SERRATED_UP | LAIHO_COLORECTAL_CANCER_SERRATED_UP | 17/1438 | 115/23056 | 0.1478261 | 2.370152 | 3.798968 | 0.0007713 | 0.0045934 | 0.0029530 | GBP1/PLA2G4A/TM4SF1/PDGFC/DDX60/PPIC/SPARC/CCN2/CAV1/C1S/EMP1/POSTN/ANXA2/EMP3/PRNP/RIN2/LGALS1 | 17 |
| HP_ASTHMA | HP_ASTHMA | HP_ASTHMA | 16/1438 | 105/23056 | 0.1523810 | 2.443182 | 3.822690 | 0.0007783 | 0.0046245 | 0.0029729 | FCGR2A/HNMT/CASP8/ADRB2/RREB1/PLA2G7/SHH/PLAG1/GAS1/ALOX5/NFKB2/HMGA2/ZIC2/IL4R/TGFB1/ARSL | 16 |
| LEIN_CHOROID_PLEXUS_MARKERS | LEIN_CHOROID_PLEXUS_MARKERS | LEIN_CHOROID_PLEXUS_MARKERS | 16/1438 | 105/23056 | 0.1523810 | 2.443182 | 3.822690 | 0.0007783 | 0.0046245 | 0.0029729 | CFH/COL8A1/ITGB5/CLDN1/RBM47/KDR/SGMS2/TGFBI/PERP/CPED1/SULF1/FZD4/LUM/LRP10/NID2/COL9A3 | 16 |
| RICKMAN_HEAD_AND_NECK_CANCER_A | RICKMAN_HEAD_AND_NECK_CANCER_A | RICKMAN_HEAD_AND_NECK_CANCER_A | 16/1438 | 105/23056 | 0.1523810 | 2.443182 | 3.822690 | 0.0007783 | 0.0046245 | 0.0029729 | CYP4X1/PRRX1/LGR6/DLX1/DLX2/CXCL5/RSPO3/MOXD1/PON3/TCIM/TNFRSF11B/ZIC2/ADGRE1/CYP24A1/COL9A3/GPC4 | 16 |
| GOBP_MAMMARY_GLAND_ALVEOLUS_DEVELOPMENT | GOBP_MAMMARY_GLAND_ALVEOLUS_DEVELOPMENT | GOBP_MAMMARY_GLAND_ALVEOLUS_DEVELOPMENT | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | TGFA/EGF/DDR1/FOXB1/FOXF1/TNFRSF11A | 6 |
| GOBP_PROSTAGLANDIN_TRANSPORT | GOBP_PROSTAGLANDIN_TRANSPORT | GOBP_PROSTAGLANDIN_TRANSPORT | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | PLA2G4A/IL1A/IL1B/SLCO2A1/EDN1/TNFRSF11A | 6 |
| HP_APLASIA_INVOLVING_BONES_OF_THE_EXTREMITIES | HP_APLASIA_INVOLVING_BONES_OF_THE_EXTREMITIES | HP_APLASIA_INVOLVING_BONES_OF_THE_EXTREMITIES | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | KCNN3/FGFR3/GJA1/GLI3/SHH/FGFR2 | 6 |
| HP_BROAD_HALLUX_PHALANX | HP_BROAD_HALLUX_PHALANX | HP_BROAD_HALLUX_PHALANX | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | GLI3/FGFR2/DACT1/SALL1/BMP2/GPC4 | 6 |
| HP_CENTRAL_OPACIFICATION_OF_THE_CORNEA | HP_CENTRAL_OPACIFICATION_OF_THE_CORNEA | HP_CENTRAL_OPACIFICATION_OF_THE_CORNEA | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | PTPN22/SLC4A4/TGFBI/FOXC1/COL18A1/IL2RB | 6 |
| REACTOME_NICOTINAMIDE_SALVAGING | REACTOME_NICOTINAMIDE_SALVAGING | REACTOME_NICOTINAMIDE_SALVAGING | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | PTGS2/PARP14/PARP10/RNLS/NNMT/PTGIS | 6 |
| REACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS | REACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS | REACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | COL3A1/MSR1/APOA1/COL1A1/COLEC12/APOE | 6 |
| VISALA_AGING_LYMPHOCYTE_DN | VISALA_AGING_LYMPHOCYTE_DN | VISALA_AGING_LYMPHOCYTE_DN | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | RUNX3/TXK/PLAAT3/GLIPR1/SDC4/COL9A3 | 6 |
| WP_OVERVIEW_OF_NANOPARTICLE_EFFECTS | WP_OVERVIEW_OF_NANOPARTICLE_EFFECTS | WP_OVERVIEW_OF_NANOPARTICLE_EFFECTS | 6/1438 | 19/23056 | 0.3157895 | 5.063173 | 4.569654 | 0.0007805 | 0.0046245 | 0.0029729 | PTGS2/FN1/CXCL8/IL6/PTGS1/HMOX1 | 6 |
| GOMF_CARBOHYDRATE_BINDING | GOMF_CARBOHYDRATE_BINDING | GOMF_CARBOHYDRATE_BINDING | 31/1438 | 270/23056 | 0.1148148 | 1.840869 | 3.584517 | 0.0007810 | 0.0046255 | 0.0029736 | PRG4/CD34/GALNT5/GALNT3/GALNT15/P3H2/GALNTL6/GALNT10/PPP1R3G/CRYBG1/GALNT17/LOXL2/COLEC10/MBL2/HKDC1/SFTPD/PPP1R3C/GALNT18/P4HA3/LAYN/KLRD1/KLRC4-KLRK1/GALNT9/PYGL/MRC2/COLEC12/CLEC4M/MAG/CD22/LGALS2/LGALS1 | 31 |
| HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN | HOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN | 13/1438 | 76/23056 | 0.1710526 | 2.742552 | 3.924386 | 0.0007855 | 0.0046472 | 0.0029875 | PTPN22/PPIC/RUNX2/ZYX/ANXA1/AHNAK/EMP1/FRMD6/ANXA2/CCL5/GRB7/DSG2/FXYD5 | 13 |
| THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP | 13/1438 | 76/23056 | 0.1710526 | 2.742552 | 3.924386 | 0.0007855 | 0.0046472 | 0.0029875 | LAMB3/IL1R1/IL1B/CXCL8/CXCL3/CXCL2/IER3/AHR/PLAU/PTPRE/CD44/BCL2A1/ZFP36 | 13 |
| IBRAHIM_NRF2_DOWN | IBRAHIM_NRF2_DOWN | IBRAHIM_NRF2_DOWN | 22/1438 | 168/23056 | 0.1309524 | 2.099609 | 3.689295 | 0.0007860 | 0.0046472 | 0.0029875 | DHRS3/ITGA10/PTGS2/GPR39/LYPD1/LAMB2/SEMA3B/PHLDB2/PLD1/PDGFC/LAMA4/CITED2/SEMA3C/PLAT/TRAF1/NRP1/STAT6/NFATC4/DACT1/HOXB7/NOG/RIN2 | 22 |
| GOBP_NEGATIVE_REGULATION_OF_MAPK_CASCADE | GOBP_NEGATIVE_REGULATION_OF_MAPK_CASCADE | GOBP_NEGATIVE_REGULATION_OF_MAPK_CASCADE | 23/1438 | 179/23056 | 0.1284916 | 2.060155 | 3.672405 | 0.0007888 | 0.0046472 | 0.0029875 | ERRFI1/GBP1/PTPN22/PTPRC/LAX1/AGT/IL1B/EPHA4/PPARG/DAB2/F2RL1/SH3RF2/CAV1/DUSP13/NLRP6/PTPRJ/FOXO1/BMP4/DACT1/APOE/SIRPA/BMP2/LIF | 23 |
| GERHOLD_RESPONSE_TO_TZD_DN | GERHOLD_RESPONSE_TO_TZD_DN | GERHOLD_RESPONSE_TO_TZD_DN | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | AGT/PPARG/CEBPD/CRYAB/APOE | 5 |
| GILMORE_CORE_NFKB_PATHWAY | GILMORE_CORE_NFKB_PATHWAY | GILMORE_CORE_NFKB_PATHWAY | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | IKBKE/NFKB2/NFKBIA/BCL3/RELB | 5 |
| GOBP_BRANCHING_INVOLVED_IN_LABYRINTHINE_LAYER_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_LABYRINTHINE_LAYER_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_LABYRINTHINE_LAYER_MORPHOGENESIS | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | GCM1/RSPO3/FGFR2/ADM/SOCS3 | 5 |
| GOBP_LEUKOCYTE_AGGREGATION | GOBP_LEUKOCYTE_AGGREGATION | GOBP_LEUKOCYTE_AGGREGATION | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | IL1B/HAS2/CD44/RAC2/MSN | 5 |
| GOBP_REGULATION_OF_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT | GOBP_REGULATION_OF_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT | GOBP_REGULATION_OF_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | TNFRSF1B/TGFB2/FOXC1/NOTCH1/TNFRSF1A | 5 |
| GOBP_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION | GOBP_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION | GOBP_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | TRIM63/CASQ1/AGT/FBXO32/SGCA | 5 |
| HP_ANURIA | HP_ANURIA | HP_ANURIA | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | CFH/AGT/CFI/C3/THBD | 5 |
| HP_INCREASED_PULMONARY_VASCULAR_RESISTANCE | HP_INCREASED_PULMONARY_VASCULAR_RESISTANCE | HP_INCREASED_PULMONARY_VASCULAR_RESISTANCE | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | SLC34A2/CITED2/CAV1/ACTC1/GATA6 | 5 |
| HP_MALAR_RASH | HP_MALAR_RASH | HP_MALAR_RASH | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | PTPN22/FCGR2A/CASP10/SPP1/STING1 | 5 |
| HP_MICROANGIOPATHIC_HEMOLYTIC_ANEMIA | HP_MICROANGIOPATHIC_HEMOLYTIC_ANEMIA | HP_MICROANGIOPATHIC_HEMOLYTIC_ANEMIA | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | CFH/SPP1/CFI/C3/THBD | 5 |
| HP_NEOPLASM_OF_THE_HEART | HP_NEOPLASM_OF_THE_HEART | HP_NEOPLASM_OF_THE_HEART | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | PTCH2/LMOD1/ACTG2/MYLK/MYH8 | 5 |
| REACTOME_FGFR3_LIGAND_BINDING_AND_ACTIVATION | REACTOME_FGFR3_LIGAND_BINDING_AND_ACTIVATION | REACTOME_FGFR3_LIGAND_BINDING_AND_ACTIVATION | 5/1438 | 13/23056 | 0.3846154 | 6.166684 | 4.805829 | 0.0007904 | 0.0046472 | 0.0029875 | GALNT3/FGFR3/FGF5/FGF18/FGF20 | 5 |
| GOBP_PITUITARY_GLAND_DEVELOPMENT | GOBP_PITUITARY_GLAND_DEVELOPMENT | GOBP_PITUITARY_GLAND_DEVELOPMENT | 9/1438 | 41/23056 | 0.2195122 | 3.519522 | 4.164462 | 0.0007923 | 0.0046472 | 0.0029875 | WNT5A/HES1/PCSK1/GLI1/BMP4/ALDH1A2/SALL1/NOG/BMP2 | 9 |
| GOBP_REGULATION_OF_BONE_RESORPTION | GOBP_REGULATION_OF_BONE_RESORPTION | GOBP_REGULATION_OF_BONE_RESORPTION | 9/1438 | 41/23056 | 0.2195122 | 3.519522 | 4.164462 | 0.0007923 | 0.0046472 | 0.0029875 | S1PR1/SPP1/TNFAIP3/IL6/PDK4/TNFRSF11B/UBASH3B/SIGLEC15/TNFRSF11A | 9 |
| HP_NON_MIDLINE_CLEFT_LIP | HP_NON_MIDLINE_CLEFT_LIP | HP_NON_MIDLINE_CLEFT_LIP | 9/1438 | 41/23056 | 0.2195122 | 3.519522 | 4.164462 | 0.0007923 | 0.0046472 | 0.0029875 | TFAP2A/GJA1/SHH/FGF20/RSPO2/ITGA8/YAP1/ZIC2/DLX4 | 9 |
| LIAO_HAVE_SOX4_BINDING_SITES | LIAO_HAVE_SOX4_BINDING_SITES | LIAO_HAVE_SOX4_BINDING_SITES | 9/1438 | 41/23056 | 0.2195122 | 3.519522 | 4.164462 | 0.0007923 | 0.0046472 | 0.0029875 | PTPN14/SERPINE2/NPNT/SEMA3C/AKR1B10/NRP1/DKK1/CREB3L1/NAV3 | 9 |
| PID_ECADHERIN_STABILIZATION_PATHWAY | PID_ECADHERIN_STABILIZATION_PATHWAY | PID_ECADHERIN_STABILIZATION_PATHWAY | 9/1438 | 41/23056 | 0.2195122 | 3.519522 | 4.164462 | 0.0007923 | 0.0046472 | 0.0029875 | EPHA2/LPP/EGF/MET/ZYX/AQP3/VCL/KIFC3/NECTIN2 | 9 |
| XU_CREBBP_TARGETS_DN | XU_CREBBP_TARGETS_DN | XU_CREBBP_TARGETS_DN | 9/1438 | 41/23056 | 0.2195122 | 3.519522 | 4.164462 | 0.0007923 | 0.0046472 | 0.0029875 | HSD11B1/EPHA4/GSN/MS4A4A/ALDH1A3/COTL1/CCR7/TGFB1/RELB | 9 |
| HP_ABNORMAL_UMBILICUS_MORPHOLOGY | HP_ABNORMAL_UMBILICUS_MORPHOLOGY | HP_ABNORMAL_UMBILICUS_MORPHOLOGY | 32/1438 | 282/23056 | 0.1134752 | 1.819391 | 3.570673 | 0.0007925 | 0.0046472 | 0.0029875 | HSPG2/LMOD1/ACTG2/COL3A1/COL5A2/TWIST2/TGFBR2/WNT5A/MYLK/ADAMTS2/RREB1/TENT5A/GJA1/GLI3/TMEM270/COLEC10/GLIS3/COL5A1/NOTCH1/FGFR2/C1S/GRIP1/FREM2/FBLN5/FBN1/SALL1/CAVIN1/COL1A1/GATA6/SCN1B/RIN2/GPC4 | 32 |
| HP_SLENDER_FINGER | HP_SLENDER_FINGER | HP_SLENDER_FINGER | 19/1438 | 136/23056 | 0.1397059 | 2.239958 | 3.740444 | 0.0007944 | 0.0046567 | 0.0029936 | PTCH2/TGFB2/CYP26B1/ACTG2/COL3A1/COL6A3/TGFBR2/MYLK/FGFR3/RREB1/COL12A1/FGFR2/EFEMP2/C1R/FBLN5/FBN1/BNC1/PIEZO2/COL6A2 | 19 |
| HP_ABNORMAL_PUPIL_MORPHOLOGY | HP_ABNORMAL_PUPIL_MORPHOLOGY | HP_ABNORMAL_PUPIL_MORPHOLOGY | 11/1438 | 58/23056 | 0.1896552 | 3.040813 | 4.013530 | 0.0008054 | 0.0047168 | 0.0030323 | ADAMTSL4/COL3A1/LAMB2/FGFRL1/SH3TC2/FOXC1/GJA1/WT1/FBN1/LOXL1/NDP | 11 |
| REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | 11/1438 | 58/23056 | 0.1896552 | 3.040813 | 4.013530 | 0.0008054 | 0.0047168 | 0.0030323 | ACKR3/ACKR2/CCR3/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/CCL5/CCR7 | 11 |
| GOBP_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | GOBP_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | GOBP_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 35/1438 | 318/23056 | 0.1100629 | 1.764680 | 3.541372 | 0.0008063 | 0.0047201 | 0.0030344 | EDN2/CRABP2/PTGS2/PLA2G4A/ATP2B4/IL1B/KYNU/CPS1/MGLL/TECRL/EDN1/CYP39A1/LGSN/PDK4/IDO1/ANXA1/PTGS1/AKR1C3/ALOX5/CARNS1/APOC3/APOA1/ALOX5AP/CYP46A1/ALDH1A2/ALDH1A3/ACSM3/CES1/GIP/LIPG/CYP4F11/PTGIS/GGTLC3/GGTLC2/GGT1 | 35 |
| HOWLIN_PUBERTAL_MAMMARY_GLAND | HOWLIN_PUBERTAL_MAMMARY_GLAND | HOWLIN_PUBERTAL_MAMMARY_GLAND | 12/1438 | 67/23056 | 0.1791045 | 2.871650 | 3.956911 | 0.0008102 | 0.0047352 | 0.0030441 | IFI16/CFH/HSD11B1/AOX1/NPR3/THBS2/PTN/MSR1/KLF4/APBB1IP/EPS8/COL18A1 | 12 |
| HP_ABNORMAL_CEREBRAL_ARTERY_MORPHOLOGY | HP_ABNORMAL_CEREBRAL_ARTERY_MORPHOLOGY | HP_ABNORMAL_CEREBRAL_ARTERY_MORPHOLOGY | 12/1438 | 67/23056 | 0.1791045 | 2.871650 | 3.956911 | 0.0008102 | 0.0047352 | 0.0030441 | LDLRAP1/TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/COL5A1/HTRA1/FBN1/COL1A1/PDGFB/BGN | 12 |
| HP_ABNORMALITY_OF_SECONDARY_SEXUAL_HAIR | HP_ABNORMALITY_OF_SECONDARY_SEXUAL_HAIR | HP_ABNORMALITY_OF_SECONDARY_SEXUAL_HAIR | 12/1438 | 67/23056 | 0.1791045 | 2.871650 | 3.956911 | 0.0008102 | 0.0047352 | 0.0030441 | CCDC141/FOXL2/ADAMTS3/FAT4/PSMB8/ZFPM2/WT1/BNC1/SOX9/ITGB4/AXL/APOE | 12 |
| MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | 12/1438 | 67/23056 | 0.1791045 | 2.871650 | 3.956911 | 0.0008102 | 0.0047352 | 0.0030441 | TNFRSF18/WNT9A/RPRM/ARHGAP24/FGF18/ID4/PERP/SEMA3D/FAS/MPZL2/PRKD1/COL9A3 | 12 |
| LIM_MAMMARY_STEM_CELL_DN | LIM_MAMMARY_STEM_CELL_DN | LIM_MAMMARY_STEM_CELL_DN | 43/1438 | 416/23056 | 0.1033654 | 1.657296 | 3.489185 | 0.0008167 | 0.0047707 | 0.0030669 | ARHGEF16/PDZK1IP1/ELF3/CAPG/KYNU/MLPH/OSBPL10/VIPR1/TMEM158/CLDN1/RBM47/BTC/TLR3/IQGAP2/RREB1/TFAP2A/PSMB8/PODXL/IDO1/PYROXD2/SLC22A18/H2AJ/KRT8/KRT18/STAT6/PPM1H/TPCN1/SLC46A3/TNFAIP2/CGNL1/ALDH1A3/CLDN7/RNF135/GRB7/KRT19/DHX58/IFI35/SLC16A5/PEX11G/LYPD3/BCL3/SDCBP2/TGM2 | 43 |
| GOBP_ACTIVATION_OF_IMMUNE_RESPONSE | GOBP_ACTIVATION_OF_IMMUNE_RESPONSE | GOBP_ACTIVATION_OF_IMMUNE_RESPONSE | 40/1438 | 379/23056 | 0.1055409 | 1.692177 | 3.504277 | 0.0008187 | 0.0047804 | 0.0030731 | ZC3H12A/GBP1/PTPN22/IFI16/CFH/PTPRC/LAX1/IL1B/TXK/TEC/CFI/C9/STING1/MOG/MICB/TNFRSF21/CLU/COLEC10/MBL2/PLPP4/TRIM5/PTPRJ/C1S/C1R/C1RL/C3AR1/KLRD1/KLRC4-KLRK1/NCKAP1L/TESPA1/CCR7/C3/CD22/KCNN4/NECTIN2/C5AR1/FPR1/PRNP/NFATC2/ICOSLG | 40 |
| GOCC_BLOOD_MICROPARTICLE | GOCC_BLOOD_MICROPARTICLE | GOCC_BLOOD_MICROPARTICLE | 20/1438 | 147/23056 | 0.1360544 | 2.181412 | 3.706050 | 0.0008241 | 0.0048099 | 0.0030921 | CFH/AGT/ACTG2/FN1/CPN2/JCHAIN/C9/CLU/GSN/HBD/APOA1/C1S/C1R/C1RL/ACTC1/C3/TGFB1/APOE/APOL1/MSN | 20 |
| BIOCARTA_NKT_PATHWAY | BIOCARTA_NKT_PATHWAY | BIOCARTA_NKT_PATHWAY | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | TGFB2/CCR3/CSF2/IL4R/CCR7/IL12RB1/TGFB1 | 7 |
| CHEN_ETV5_TARGETS_SERTOLI | CHEN_ETV5_TARGETS_SERTOLI | CHEN_ETV5_TARGETS_SERTOLI | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | CD53/FCGR2A/CXCL6/IL6/GPNMB/CD36/THBD | 7 |
| GOBP_CELL_ADHESION_MOLECULE_PRODUCTION | GOBP_CELL_ADHESION_MOLECULE_PRODUCTION | GOBP_CELL_ADHESION_MOLECULE_PRODUCTION | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | IL1B/CXCL8/CAV1/NOTCH1/APOA1/MYOCD/COLEC12 | 7 |
| GOBP_POSITIVE_REGULATION_OF_COLLAGEN_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_COLLAGEN_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_COLLAGEN_METABOLIC_PROCESS | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | ITGA2/CCN2/CREB3L1/BMP4/SERPINB7/TGFB1/RUNX1 | 7 |
| GOBP_REGULATION_OF_POSITIVE_CHEMOTAXIS | GOBP_REGULATION_OF_POSITIVE_CHEMOTAXIS | GOBP_REGULATION_OF_POSITIVE_CHEMOTAXIS | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | S1PR1/KDR/CXCL8/VEGFC/ITGA2/F2RL1/CDH13 | 7 |
| GOBP_RESPONSE_TO_INCREASED_OXYGEN_LEVELS | GOBP_RESPONSE_TO_INCREASED_OXYGEN_LEVELS | GOBP_RESPONSE_TO_INCREASED_OXYGEN_LEVELS | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | SOD2/CAV1/FAS/KCNA5/FOXO1/MMP2/COL1A1 | 7 |
| HP_ESOPHAGEAL_NEOPLASM | HP_ESOPHAGEAL_NEOPLASM | HP_ESOPHAGEAL_NEOPLASM | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | TGFBR2/MSR1/CTHRC1/COL14A1/RHBDF2/COL4A6/COL4A5 | 7 |
| HP_ESOPHAGEAL_STENOSIS | HP_ESOPHAGEAL_STENOSIS | HP_ESOPHAGEAL_STENOSIS | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | LAMC2/LAMB3/COL7A1/SAMD9/MMP1/COL4A6/COL4A5 | 7 |
| LI_CISPLATIN_RESISTANCE_UP | LI_CISPLATIN_RESISTANCE_UP | LI_CISPLATIN_RESISTANCE_UP | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | KYNU/EPHA3/HAPLN1/GJA1/CEMIP2/UACA/ITM2A | 7 |
| NEWMAN_ERCC6_TARGETS_UP | NEWMAN_ERCC6_TARGETS_UP | NEWMAN_ERCC6_TARGETS_UP | 7/1438 | 26/23056 | 0.2692308 | 4.316679 | 4.364127 | 0.0008318 | 0.0048344 | 0.0031079 | KYNU/CXCL8/CXCL2/GPAT3/SLC7A11/PCSK5/CRIP1 | 7 |
| GOBP_MYOBLAST_DIFFERENTIATION | GOBP_MYOBLAST_DIFFERENTIATION | GOBP_MYOBLAST_DIFFERENTIATION | 14/1438 | 86/23056 | 0.1627907 | 2.610085 | 3.858085 | 0.0008361 | 0.0048575 | 0.0031227 | RBM24/SHH/NOTCH1/TCF7L2/WNT10B/IGF1/BMP4/ZFP36L1/SOX8/MYOCD/SOX9/TNFSF14/TGFB1/LGALS1 | 14 |
| HP_ABNORMAL_BRONCHUS_MORPHOLOGY | HP_ABNORMAL_BRONCHUS_MORPHOLOGY | HP_ABNORMAL_BRONCHUS_MORPHOLOGY | 21/1438 | 158/23056 | 0.1329114 | 2.131019 | 3.679204 | 0.0008427 | 0.0048935 | 0.0031458 | FCGR2A/CFAP221/SLC34A2/DNAH5/MCIDAS/CCNO/DSP/TAPBP/NFKB2/FGFR2/MYRF/SCNN1A/NCKAP1L/IRF9/IL21R/LAT/SOX9/TGFB1/RIN2/RAC2/ARSL | 21 |
| GOBP_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | GOBP_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | GOBP_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | 17/1438 | 116/23056 | 0.1465517 | 2.349719 | 3.758634 | 0.0008522 | 0.0049468 | 0.0031801 | PTPRC/AGT/PPARG/PARP14/HES1/EGF/IL7R/TSLP/IL6/CAV1/IFNE/NOTCH1/CCL5/SOCS3/TGFB1/BCL3/LIF | 17 |
| GOBP_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 45/1438 | 442/23056 | 0.1018100 | 1.632358 | 3.462099 | 0.0008588 | 0.0049828 | 0.0032033 | ERRFI1/CDA/ZC3H12A/PTPN22/NIBAN1/PTPRC/LAX1/TGFB2/AGT/IL1B/PPARG/PARP14/HEG1/WWTR1/ZFYVE28/SLIT2/CD109/TNFAIP3/PDGFA/INHBA/CAV1/FABP4/ANGPT1/DKK1/HHEX/PTPRJ/UBASH3B/GPRC5A/NCKAP1L/LATS2/AJUBA/BMP4/BDKRB1/SMAD6/NUPR1/MYOCD/NOG/SOCS3/GADD45B/TGFB1/APOE/SIRPA/PRNP/BMP2/PDGFB | 45 |
| GOBP_OSTEOCLAST_DIFFERENTIATION | GOBP_OSTEOCLAST_DIFFERENTIATION | GOBP_OSTEOCLAST_DIFFERENTIATION | 15/1438 | 96/23056 | 0.1562500 | 2.505216 | 3.811559 | 0.0008608 | 0.0049927 | 0.0032096 | EPHA2/CSF1/MITF/TLR3/CD109/FAM20C/CCN4/UBASH3B/FOS/FBN1/ANXA2/SIGLEC15/TNFRSF11A/FSTL3/CEBPB | 15 |
| HP_ABNORMALITY_OF_THE_DIAPHRAGM | HP_ABNORMALITY_OF_THE_DIAPHRAGM | HP_ABNORMALITY_OF_THE_DIAPHRAGM | 16/1438 | 106/23056 | 0.1509434 | 2.420133 | 3.779591 | 0.0008646 | 0.0050105 | 0.0032211 | RARB/CD96/ADGRG6/GLI3/SHH/ZFPM2/RSPO2/WT1/EFEMP2/ZIC2/DACT1/FBLN5/MAF/GATA6/MN1/GPC4 | 16 |
| ROESSLER_LIVER_CANCER_METASTASIS_UP | ROESSLER_LIVER_CANCER_METASTASIS_UP | ROESSLER_LIVER_CANCER_METASTASIS_UP | 16/1438 | 106/23056 | 0.1509434 | 2.420133 | 3.779591 | 0.0008646 | 0.0050105 | 0.0032211 | CCR3/CDS1/SPP1/MDFI/RHAG/ASPH/ALDH3B1/EPB42/CES1/CTRB1/CDH13/HOXB13/CD37/IL2RB/COL4A5/GABRE | 16 |
| HP_ABNORMALITY_OF_THE_PERIORBITAL_REGION | HP_ABNORMALITY_OF_THE_PERIORBITAL_REGION | HP_ABNORMALITY_OF_THE_PERIORBITAL_REGION | 30/1438 | 260/23056 | 0.1153846 | 1.850005 | 3.554948 | 0.0008682 | 0.0050292 | 0.0032331 | PTPN22/COL5A2/TWIST2/PPARG/FGFR3/ARHGAP24/ADAMTS2/PSMB9/CITED2/TMEM270/CAV1/ZFPM2/GSN/CRB2/COL5A1/FGFR2/WT1/TNFRSF1A/FOS/MYO1E/PIEZO1/CAVIN1/COL1A1/GATA6/RIN2/GATA5/APOL1/FRMPD4/TBC1D8B/ARHGEF6 | 30 |
| HP_ABNORMAL_URETER_MORPHOLOGY | HP_ABNORMAL_URETER_MORPHOLOGY | HP_ABNORMAL_URETER_MORPHOLOGY | 19/1438 | 137/23056 | 0.1386861 | 2.223607 | 3.704749 | 0.0008695 | 0.0050345 | 0.0032365 | LAMC2/LMOD1/LAMB3/ACTG2/ITGA6/MYLK/PLD1/TBX18/FAM20C/GLI3/GLI1/FOXF1/LHX1/ITGB4/PIEZO2/GATA6/SCN1B/COL18A1/GPC4 | 19 |
| KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION | KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION | KYNG_DNA_DAMAGE_BY_GAMMA_RADIATION | 13/1438 | 77/23056 | 0.1688312 | 2.706934 | 3.869464 | 0.0008920 | 0.0051588 | 0.0033164 | SYNC/TIE1/GBP1/CRABP2/NRP2/SEMA3B/MITF/SLCO2A1/HBEGF/DOCK2/CYP39A1/MET/PCSK5 | 13 |
| MUNSHI_MULTIPLE_MYELOMA_UP | MUNSHI_MULTIPLE_MYELOMA_UP | MUNSHI_MULTIPLE_MYELOMA_UP | 13/1438 | 77/23056 | 0.1688312 | 2.706934 | 3.869464 | 0.0008920 | 0.0051588 | 0.0033164 | CSF1/FGFR3/CSF2/ZC3H12D/ANGPT1/KRT8/NFKBIA/FOS/ANXA2/CD68/ABCC3/AXL/RELB | 13 |
| GOBP_ACTIVATED_T_CELL_PROLIFERATION | GOBP_ACTIVATED_T_CELL_PROLIFERATION | GOBP_ACTIVATED_T_CELL_PROLIFERATION | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | IDO1/CD274/PDCD1LG2/LRRC32/IGF1/TNFSF9/IL27RA/IL12RB1/PRNP/ICOSLG | 10 |
| GOBP_FOREBRAIN_GENERATION_OF_NEURONS | GOBP_FOREBRAIN_GENERATION_OF_NEURONS | GOBP_FOREBRAIN_GENERATION_OF_NEURONS | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | DLX1/DLX2/NRP2/HES1/LEF1/INHBA/GLI3/SEMA3A/NRP1/FGFR2 | 10 |
| HP_ABNORMALITY_OF_THE_THORACIC_CAVITY | HP_ABNORMALITY_OF_THE_THORACIC_CAVITY | HP_ABNORMALITY_OF_THE_THORACIC_CAVITY | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | PTPN22/BCL6/WT1/EFEMP2/BIRC3/STAT6/FBLN5/RHBDF2/APOE/PDGFB | 10 |
| HP_PREMATURE_LOSS_OF_TEETH | HP_PREMATURE_LOSS_OF_TEETH | HP_PREMATURE_LOSS_OF_TEETH | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | GFI1/COL3A1/RUNX2/GJA1/TNFRSF11B/C1S/C1R/PRKD1/TNFRSF11A/ELANE | 10 |
| HP_YELLOW_WHITE_LESIONS_OF_THE_RETINA | HP_YELLOW_WHITE_LESIONS_OF_THE_RETINA | HP_YELLOW_WHITE_LESIONS_OF_THE_RETINA | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | RPE65/HMCN1/CFH/EFEMP1/CFI/TSPAN12/FZD4/FBLN5/APOE/NDP | 10 |
| NOUSHMEHR_GBM_SILENCED_BY_METHYLATION | NOUSHMEHR_GBM_SILENCED_BY_METHYLATION | NOUSHMEHR_GBM_SILENCED_BY_METHYLATION | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | SPON2/SEL1L3/FLNC/RARRES2/CA3/FZD6/CTHRC1/PAMR1/BIRC3/ACSS3 | 10 |
| REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | AGRN/HSPG2/CHSY3/UST/CSGALNACT1/CSPG4/SDC4/CHST7/GPC4/BGN | 10 |
| WARTERS_IR_RESPONSE_5GY | WARTERS_IR_RESPONSE_5GY | WARTERS_IR_RESPONSE_5GY | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | SH2D2A/CAVIN2/GASK1B/GDNF/TNFRSF10C/LRATD2/NOTCH1/FAS/RRAD/GDF15 | 10 |
| WP_HEPATITIS_C_AND_HEPATOCELLULAR_CARCINOMA | WP_HEPATITIS_C_AND_HEPATOCELLULAR_CARCINOMA | WP_HEPATITIS_C_AND_HEPATOCELLULAR_CARCINOMA | 10/1438 | 50/23056 | 0.2000000 | 3.206676 | 4.028629 | 0.0008951 | 0.0051588 | 0.0033164 | PTGS2/CXCL8/LEF1/IL6/PODXL/MYOF/CD44/BIRC3/MMP1/TGFB1 | 10 |
| HP_ACUTE_PHASE_RESPONSE | HP_ACUTE_PHASE_RESPONSE | HP_ACUTE_PHASE_RESPONSE | 20/1438 | 148/23056 | 0.1351351 | 2.166673 | 3.672321 | 0.0008982 | 0.0051720 | 0.0033249 | PTPN22/HJV/NLRP3/CASP10/SPP1/TLR3/STING1/HFE/PSMB8/PSMB9/STX11/IL6/TNFRSF1A/SLC7A7/PSMB10/PIEZO1/TGFB1/KCNN4/BMP2/IL2RB | 20 |
| RYAN_MANTLE_CELL_LYMPHOMA_NOTCH_DIRECT_UP | RYAN_MANTLE_CELL_LYMPHOMA_NOTCH_DIRECT_UP | RYAN_MANTLE_CELL_LYMPHOMA_NOTCH_DIRECT_UP | 20/1438 | 148/23056 | 0.1351351 | 2.166673 | 3.672321 | 0.0008982 | 0.0051720 | 0.0033249 | TNFRSF1B/RUNX3/S1PR1/MGLL/HES1/PLAC8/GALNT10/ADTRP/UST/B4GALT1/DNMBP/CD82/UBASH3B/ZFP36L1/BCL2A1/IL21R/GADD45B/ICAM1/ZFP36/MX2 | 20 |
| REACTOME_LEISHMANIA_INFECTION | REACTOME_LEISHMANIA_INFECTION | REACTOME_LEISHMANIA_INFECTION | 34/1438 | 308/23056 | 0.1103896 | 1.769918 | 3.508349 | 0.0009020 | 0.0051916 | 0.0033375 | FCGR2A/NLRP3/IL1A/IL1B/SCTR/GPR39/VIPR1/WNT5A/MYO10/PLK2/ADRB2/ITPR3/NT5E/IL6/WIPF3/ADCY8/GPR20/GSDMD/HTR7/NFKB2/ADM/CASP1/C3AR1/NCKAP1L/GLP2R/MYH2/GIP/GNGT2/RHBDF2/C3/GGT1/HMOX1/MYH9/CYSLTR1 | 34 |
| GOBP_ADAPTIVE_THERMOGENESIS | GOBP_ADAPTIVE_THERMOGENESIS | GOBP_ADAPTIVE_THERMOGENESIS | 21/1438 | 159/23056 | 0.1320755 | 2.117616 | 3.647172 | 0.0009151 | 0.0052605 | 0.0033818 | SCTR/TRPM8/PLAC8/IL15/PDGFC/NPR3/ADRB2/LAMA4/GJA1/CD36/CAV1/EBF2/FABP4/NOTCH1/WNT10B/STAT6/DIO2/IL4R/TRPV2/CEBPB/ADAMTS5 | 21 |
| GOMF_LIPID_TRANSPORTER_ACTIVITY | GOMF_LIPID_TRANSPORTER_ACTIVITY | GOMF_LIPID_TRANSPORTER_ACTIVITY | 21/1438 | 159/23056 | 0.1320755 | 2.117616 | 3.647172 | 0.0009151 | 0.0052605 | 0.0033818 | OSBPL10/SLCO2A1/PLSCR4/PLSCR2/ATP10B/CD36/FABP4/SLCO2B1/APOA1/SLC10A2/TNFAIP8L3/CETP/PITPNM3/ABCC3/ABCA8/ABCA9/ABCA6/ABCA10/ATP8B3/APOE/APOL3 | 21 |
| HP_JUVENILE_ONSET | HP_JUVENILE_ONSET | HP_JUVENILE_ONSET | 21/1438 | 159/23056 | 0.1320755 | 2.117616 | 3.647172 | 0.0009151 | 0.0052605 | 0.0033818 | TNFRSF4/TIE1/CFH/NLRP3/GALNT3/CASP10/SLCO2A1/CLDN16/DOK7/CFI/TRDN/LAMA2/TNFAIP3/EXT1/PYGM/FBN1/MMP2/SGCA/TGFB1/COL6A2/MYH9 | 21 |
| HP_ABNORMAL_THROMBOCYTE_MORPHOLOGY | HP_ABNORMAL_THROMBOCYTE_MORPHOLOGY | HP_ABNORMAL_THROMBOCYTE_MORPHOLOGY | 42/1438 | 406/23056 | 0.1034483 | 1.658626 | 3.453200 | 0.0009182 | 0.0052763 | 0.0033919 | PTPN22/FCGR2A/PLA2G4A/CFH/NLRP3/NABP1/CASP10/SP110/SPP1/CFI/IL7R/ITGA2/STING1/RREB1/PSMB8/PSMB9/CD109/TENT5A/TNFAIP3/STX11/CD36/SAMD9/SAMD9L/NOTCH1/PLAU/FAS/NFKB2/VWF/FLT1/SLC7A7/LAT/ELANE/C3/TGFB1/APOE/RRAS/THBD/RUNX1/USP18/MYH9/PDGFB/COL4A5 | 42 |
| GOBP_INTERMEDIATE_FILAMENT_BASED_PROCESS | GOBP_INTERMEDIATE_FILAMENT_BASED_PROCESS | GOBP_INTERMEDIATE_FILAMENT_BASED_PROCESS | 12/1438 | 68/23056 | 0.1764706 | 2.829420 | 3.896472 | 0.0009289 | 0.0053334 | 0.0034287 | SYNC/TCHH/DES/DSP/SHH/EPPK1/KRT18/KRT13/KRT15/KRT19/KRT17/BFSP1 | 12 |
| JI_RESPONSE_TO_FSH_UP | JI_RESPONSE_TO_FSH_UP | JI_RESPONSE_TO_FSH_UP | 12/1438 | 68/23056 | 0.1764706 | 2.829420 | 3.896472 | 0.0009289 | 0.0053334 | 0.0034287 | COL3A1/PSMB9/CRYBG1/LAMA4/CLU/AKR1C3/PLAAT4/CASP1/C1R/IFI35/AXL/BFSP1 | 12 |
| GOBP_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS | 11/1438 | 59/23056 | 0.1864407 | 2.989274 | 3.945838 | 0.0009350 | 0.0053527 | 0.0034410 | ERRFI1/EDN1/AQP1/STC1/PLAT/FBXO32/ANXA1/AKR1C3/FLT3/ZFP36L1/ZFP36 | 11 |
| GOBP_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | 11/1438 | 59/23056 | 0.1864407 | 2.989274 | 3.945838 | 0.0009350 | 0.0053527 | 0.0034410 | ZC3H12A/PTPRC/BCL6/IL7R/HFE/AHR/KLRD1/NCKAP1L/IL4R/IL27RA/IL4I1 | 11 |
| GOBP_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 11/1438 | 59/23056 | 0.1864407 | 2.989274 | 3.945838 | 0.0009350 | 0.0053527 | 0.0034410 | WNT5A/WWTR1/ID4/SOD2/IL6/ZFPM2/CCN4/YAP1/WNT10B/FOXO1/TGFB1 | 11 |
| HP_ABNORMALITY_OF_THE_PERITONEUM | HP_ABNORMALITY_OF_THE_PERITONEUM | HP_ABNORMALITY_OF_THE_PERITONEUM | 11/1438 | 59/23056 | 0.1864407 | 2.989274 | 3.945838 | 0.0009350 | 0.0053527 | 0.0034410 | BCL6/ARHGAP24/SERPINE1/CRB2/WT1/TNFRSF1A/STAT6/MYO1E/ELANE/APOL1/TBC1D8B | 11 |
| HP_BUNDLE_BRANCH_BLOCK | HP_BUNDLE_BRANCH_BLOCK | HP_BUNDLE_BRANCH_BLOCK | 11/1438 | 59/23056 | 0.1864407 | 2.989274 | 3.945838 | 0.0009350 | 0.0053527 | 0.0034410 | TNNC1/MYOZ2/CITED2/SEMA3A/SCNN1A/ACTC1/HCN4/JUP/GATA6/SCN1B/GPC4 | 11 |
| MIKKELSEN_NPC_LCP_WITH_H3K4ME3 | MIKKELSEN_NPC_LCP_WITH_H3K4ME3 | MIKKELSEN_NPC_LCP_WITH_H3K4ME3 | 11/1438 | 59/23056 | 0.1864407 | 2.989274 | 3.945838 | 0.0009350 | 0.0053527 | 0.0034410 | GBP2/C1orf54/CAMK1G/AGT/DDR1/GPSM3/MMP1/VWA5A/TNS2/SERPINB8/MLC1 | 11 |
| REACTOME_ARACHIDONIC_ACID_METABOLISM | REACTOME_ARACHIDONIC_ACID_METABOLISM | REACTOME_ARACHIDONIC_ACID_METABOLISM | 11/1438 | 59/23056 | 0.1864407 | 2.989274 | 3.945838 | 0.0009350 | 0.0053527 | 0.0034410 | PTGS2/PLA2G4A/PON3/PTGR1/PTGS1/AKR1C3/ALOX5/ALOX5AP/CYP4F11/PTGIS/GGT1 | 11 |
| GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_PROLIFERATION | 14/1438 | 87/23056 | 0.1609195 | 2.580084 | 3.808229 | 0.0009403 | 0.0053745 | 0.0034551 | LDLRAP1/AGT/PPARG/EDN1/GJA1/SOD2/EFEMP2/IGF1/TPM1/MMP2/MYOCD/CNN1/HMOX1/PDGFB | 14 |
| WP_ACUTE_VIRAL_MYOCARDITIS | WP_ACUTE_VIRAL_MYOCARDITIS | WP_ACUTE_VIRAL_MYOCARDITIS | 14/1438 | 87/23056 | 0.1609195 | 2.580084 | 3.808229 | 0.0009403 | 0.0053745 | 0.0034551 | CASP8/CCR3/TLR3/EDN1/MICA/LAMA2/IL6/CAV1/NFKB2/CASP1/KRT8/SGCA/TGFB1/RAC2 | 14 |
| HOELZEL_NF1_TARGETS_DN | HOELZEL_NF1_TARGETS_DN | HOELZEL_NF1_TARGETS_DN | 17/1438 | 117/23056 | 0.1452991 | 2.329636 | 3.718714 | 0.0009403 | 0.0053745 | 0.0034551 | TMEM200B/HMCN1/COL3A1/FN1/WNT5A/FSTL1/PDK4/MATN2/ADM/MYRF/LATS2/DNAJC15/EDNRB/PRKD1/ADAMTS5/CHST7/BGN | 17 |
| YAGI_AML_WITH_11Q23_REARRANGED | YAGI_AML_WITH_11Q23_REARRANGED | YAGI_AML_WITH_11Q23_REARRANGED | 37/1438 | 345/23056 | 0.1072464 | 1.719522 | 3.472879 | 0.0009407 | 0.0053745 | 0.0034551 | HSPG2/S100A10/RASGRP3/CAPG/GYPC/DPP4/SEL1L3/NPR3/FOXC1/GMPR/HFE/MICB/CCN2/SASH1/SEMA3C/RARRES2/RBPMS/FZD6/PYGM/ITGA7/HMGA2/CPM/LUM/ALOX5AP/LCP1/LRP10/CSPG4/ANPEP/CD68/IFI35/SLC16A5/COL6A2/GGT1/MYH9/LGALS1/ITM2A/TENM1 | 37 |
| MULLIGHAN_MLL_SIGNATURE_1_DN | MULLIGHAN_MLL_SIGNATURE_1_DN | MULLIGHAN_MLL_SIGNATURE_1_DN | 28/1438 | 238/23056 | 0.1176471 | 1.886280 | 3.544662 | 0.0009408 | 0.0053745 | 0.0034551 | AGRN/EDN2/TIE1/PTPN14/TFPI/SERPINE2/LAMB2/TM4SF1/STK32B/CXCL8/CXCL2/NPR3/TNFRSF21/CAV1/RBPMS/MYRF/KRT18/NID2/LOXL1/MMP2/CETP/MAF/CAVIN1/HOXB2/RUNX1/SSX1/ITM2A/GABRE | 28 |
| PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | 32/1438 | 285/23056 | 0.1122807 | 1.800239 | 3.505947 | 0.0009472 | 0.0053870 | 0.0034631 | ATP2B4/LAX1/ITGB5/SLC12A8/FNDC3B/RBM47/ELL2/STING1/DSP/FILIP1/CITED2/FOXP2/CPED1/ASPH/MATN2/CCN4/EPPK1/IFITM3/PRRG4/CD44/YAP1/MPZL2/PHLDA1/SELPLG/RAB20/UACA/MT1X/WIPI1/MYOM1/KCNN4/TGM2/CEBPB | 32 |
| GOBP_EPIDERMIS_MORPHOGENESIS | GOBP_EPIDERMIS_MORPHOGENESIS | GOBP_EPIDERMIS_MORPHOGENESIS | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | TGFB2/FST/SHH/EXT1/KLF4/NOTCH1/FGFR2/KRT17 | 8 |
| GOBP_HEAD_MORPHOGENESIS | GOBP_HEAD_MORPHOGENESIS | GOBP_HEAD_MORPHOGENESIS | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | LEF1/ASPH/DKK1/MMP2/CRISPLD2/COL1A1/NOG/RRAS | 8 |
| GOBP_LEUKOTRIENE_METABOLIC_PROCESS | GOBP_LEUKOTRIENE_METABOLIC_PROCESS | GOBP_LEUKOTRIENE_METABOLIC_PROCESS | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | PLA2G4A/PTGR1/ALOX5/ALOX5AP/CYP4F11/GGTLC3/GGTLC2/GGT1 | 8 |
| GOBP_PROXIMAL_DISTAL_PATTERN_FORMATION | GOBP_PROXIMAL_DISTAL_PATTERN_FORMATION | GOBP_PROXIMAL_DISTAL_PATTERN_FORMATION | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | OSR1/CYP26B1/DLX1/DLX2/IRX2/GLI3/GLI1/ALDH1A2 | 8 |
| GOBP_RESPONSE_TO_FLUID_SHEAR_STRESS | GOBP_RESPONSE_TO_FLUID_SHEAR_STRESS | GOBP_RESPONSE_TO_FLUID_SHEAR_STRESS | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | PTGS2/CSF2/CITED2/HAS2/KLF4/SMAD6/MMP2/KLF2 | 8 |
| GOCC_A_BAND | GOCC_A_BAND | GOCC_A_BAND | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | TRIM63/MYL7/LMOD2/CRYAB/MYH1/MYL4/MYOM1/SMPX | 8 |
| HP_BILIARY_CIRRHOSIS | HP_BILIARY_CIRRHOSIS | HP_BILIARY_CIRRHOSIS | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | FCGR2A/HFE/TNFSF15/SERPINA1/IL12RB1/TGFB1/KCNN4/HMOX1 | 8 |
| HP_NEONATAL_DEATH | HP_NEONATAL_DEATH | HP_NEONATAL_DEATH | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | HSPG2/LMOD1/FGFR3/DSP/FAM20C/GLI3/WT1/FOXF1 | 8 |
| HP_SYSTEMIC_LUPUS_ERYTHEMATOSUS | HP_SYSTEMIC_LUPUS_ERYTHEMATOSUS | HP_SYSTEMIC_LUPUS_ERYTHEMATOSUS | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | PTPN22/FCGR2A/CASP10/SPP1/FAS/C1S/SEMA6B/C3 | 8 |
| VALK_AML_CLUSTER_6 | VALK_AML_CLUSTER_6 | VALK_AML_CLUSTER_6 | 8/1438 | 34/23056 | 0.2352941 | 3.772560 | 4.172565 | 0.0009473 | 0.0053870 | 0.0034631 | CFH/LTBP1/SNCAIP/FOXC1/HOXB3/PECAM1/PIEZO2/GPC4 | 8 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_IMPORT | GOBP_POSITIVE_REGULATION_OF_PROTEIN_IMPORT | GOBP_POSITIVE_REGULATION_OF_PROTEIN_IMPORT | 9/1438 | 42/23056 | 0.2142857 | 3.435724 | 4.074844 | 0.0009533 | 0.0054098 | 0.0034778 | ZC3H12A/PTGS2/GLI3/ARHGEF5/SHH/BAG3/PRKD1/JUP/TGFB1 | 9 |
| GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | 9/1438 | 42/23056 | 0.2142857 | 3.435724 | 4.074844 | 0.0009533 | 0.0054098 | 0.0034778 | S100A11/AGT/ITGA2/HAS2/CCN4/NRP1/IGF1/CCL5/PDGFB | 9 |
| HP_EPIDERMAL_ACANTHOSIS | HP_EPIDERMAL_ACANTHOSIS | HP_EPIDERMAL_ACANTHOSIS | 9/1438 | 42/23056 | 0.2142857 | 3.435724 | 4.074844 | 0.0009533 | 0.0054098 | 0.0034778 | CLDN1/DSP/GJA1/PERP/COL14A1/KRT13/JUP/SERPINB7/SERPINB8 | 9 |
| KORKOLA_TERATOMA | KORKOLA_TERATOMA | KORKOLA_TERATOMA | 9/1438 | 42/23056 | 0.2142857 | 3.435724 | 4.074844 | 0.0009533 | 0.0054098 | 0.0034778 | TM4SF1/PLAT/COL14A1/EHF/EMP1/EPS8/CLDN6/ZFP36/CLIC6 | 9 |
| ZHAN_MULTIPLE_MYELOMA_DN | ZHAN_MULTIPLE_MYELOMA_DN | ZHAN_MULTIPLE_MYELOMA_DN | 9/1438 | 42/23056 | 0.2142857 | 3.435724 | 4.074844 | 0.0009533 | 0.0054098 | 0.0034778 | VCAM1/HNMT/PLA2G7/CEBPD/HHEX/WNT10B/PYGL/ELANE/APOE | 9 |
| GOBP_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM | GOBP_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM | GOBP_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM | 16/1438 | 107/23056 | 0.1495327 | 2.397515 | 3.736979 | 0.0009589 | 0.0054398 | 0.0034971 | EPHA2/GBP2/GBP4/MR1/IL7R/HLA-E/IL6/CD36/RARRES2/DEFB107B/GSDMD/MBL2/NLRP6/KLRC4-KLRK1/IL27RA/C5AR1 | 16 |
| BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_RUXOLITINIB_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_RUXOLITINIB_UP | BLANCO_MELO_COVID19_SARS_COV_2_INFECTION_A594_ACE2_EXPRESSING_CELLS_RUXOLITINIB_UP | 48/1438 | 483/23056 | 0.0993789 | 1.593379 | 3.399113 | 0.0009917 | 0.0056235 | 0.0036152 | TNFRSF9/ZC3H12A/RASSF5/CCDC85A/IL1A/IRAK2/ARL14/HES1/CXCL8/CXCL1/CXCL3/CXCL2/EREG/FGF18/H3C6/H1-3/IER3/TNFAIP3/STX11/ADAM32/KLF4/TRAF1/NFKB2/ADM/PYGM/FOSL1/BIRC3/BHLHE41/OASL/NFKBIA/SIX4/FOS/ESRRB/SERPINA10/BMF/BCL2A1/ALPK3/SALL1/USP43/SOX9/GDF15/ZFP36/BCL3/RELB/IL11/SIM2/LIF/PDGFB | 48 |
| HP_FACIAL_ASYMMETRY | HP_FACIAL_ASYMMETRY | HP_FACIAL_ASYMMETRY | 18/1438 | 128/23056 | 0.1406250 | 2.254694 | 3.671250 | 0.0009976 | 0.0056546 | 0.0036352 | FN1/FGFRL1/FGFR3/EDN1/GDF6/FGFR2/BMP4/DACT1/SIX1/SALL1/MAF/MYH8/MEOX1/COL1A1/NOG/KCNJ2/PIEZO2/SIX5 | 18 |
| GOBP_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | GOBP_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | GOBP_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 40/1438 | 383/23056 | 0.1044386 | 1.674504 | 3.433080 | 0.0010013 | 0.0056729 | 0.0036469 | ERRFI1/ZC3H12A/PTPN22/NIBAN1/PTPRC/LAX1/AGT/IL1B/PPARG/PARP14/HEG1/WWTR1/ZFYVE28/SLIT2/CD109/TNFAIP3/INHBA/CAV1/FABP4/ANGPT1/DKK1/HHEX/PTPRJ/UBASH3B/GPRC5A/LATS2/AJUBA/BMP4/BDKRB1/SMAD6/NUPR1/MYOCD/NOG/SOCS3/GADD45B/TGFB1/APOE/SIRPA/PRNP/BMP2 | 40 |
| GOCC_CELL_CORTEX | GOCC_CELL_CORTEX | GOCC_CELL_CORTEX | 34/1438 | 310/23056 | 0.1096774 | 1.758500 | 3.467672 | 0.0010092 | 0.0057149 | 0.0036739 | RHOC/LAMC2/HMCN1/GYPC/MLPH/PHLDB2/MYO10/RAI14/CLIC5/CCN2/UTRN/SCIN/CAV1/ASPH/AQP7/GSN/FGFR2/EPS8/RND1/TRPC4/PRKD1/EXOC3L4/TNFAIP2/EPB42/MYO1E/COTL1/KRT19/FMNL1/LLGL2/PLA2G4C/BFSP1/MYL9/MYH9/RAC2 | 34 |
| GOBP_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | GOBP_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | GOBP_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | 13/1438 | 78/23056 | 0.1666667 | 2.672230 | 3.815412 | 0.0010104 | 0.0057149 | 0.0036739 | PTGS2/KDR/PLK2/ANXA1/KLF4/NOTCH1/JCAD/NRP1/MMRN2/THBS1/HMOX1/CARD10/SRPX2 | 13 |
| GOMF_SMAD_BINDING | GOMF_SMAD_BINDING | GOMF_SMAD_BINDING | 13/1438 | 78/23056 | 0.1666667 | 2.672230 | 3.815412 | 0.0010104 | 0.0057149 | 0.0036739 | COL3A1/COL5A2/PPARG/TGFBR2/DAB2/CITED2/ANKRD1/CREB3L1/HMGA2/FOS/SMAD6/MYOCD/BMP2 | 13 |
| HP_SCAPULAR_WINGING | HP_SCAPULAR_WINGING | HP_SCAPULAR_WINGING | 13/1438 | 78/23056 | 0.1666667 | 2.672230 | 3.815412 | 0.0010104 | 0.0057149 | 0.0036739 | COL6A3/LAMB2/SH3TC2/COL12A1/CSGALNACT1/TRPS1/TPM2/MYPN/FBN1/MYH2/SGCA/KCNJ2/COL6A2 | 13 |
| YAGI_AML_WITH_T_8_21_TRANSLOCATION | YAGI_AML_WITH_T_8_21_TRANSLOCATION | YAGI_AML_WITH_T_8_21_TRANSLOCATION | 39/1438 | 371/23056 | 0.1051213 | 1.685450 | 3.432791 | 0.0010178 | 0.0057547 | 0.0036995 | AGRN/FCGR2A/IKBKE/CD34/CAPG/VAMP5/GYPC/LYPD1/TFPI/SERPINE2/ACKR3/UBA7/CD96/IL1RAP/DDR1/TNFRSF21/CAV2/CAV1/TEK/AKR1C3/MYRF/TNFRSF1A/SELPLG/LCP1/FBLN5/TNFAIP2/ACSM3/NUPR1/CD68/JUP/GIP/ITGB4/SOCS3/ELANE/IL27RA/BCAM/LGALS1/STARD8/ARHGEF6 | 39 |
| GOBP_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 19/1438 | 139/23056 | 0.1366906 | 2.191613 | 3.634277 | 0.0010381 | 0.0058672 | 0.0037718 | GBP5/IFI16/IKBKE/NMI/WNT5A/TXK/EREG/STING1/HLA-E/RAET1E/TRIM56/MBL2/TRIM5/KLRD1/KLRC4-KLRK1/NLRC5/CCL5/IFI35/NECTIN2 | 19 |
| GOBP_NEGATIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 10/1438 | 51/23056 | 0.1960784 | 3.143800 | 3.952869 | 0.0010521 | 0.0059058 | 0.0037967 | CRIM1/TWIST2/PPARG/OSTN/VEGFC/HOXA2/NOTCH1/SMAD6/NOG/SOX9 | 10 |
| HP_EMPHYSEMA | HP_EMPHYSEMA | HP_EMPHYSEMA | 10/1438 | 51/23056 | 0.1960784 | 3.143800 | 3.952869 | 0.0010521 | 0.0059058 | 0.0037967 | TGFB2/COL3A1/TAPBP/NFKB2/EFEMP2/SCNN1A/GLI1/FBLN5/SERPINA1/FBN1 | 10 |
| HP_JOINT_SWELLING | HP_JOINT_SWELLING | HP_JOINT_SWELLING | 10/1438 | 51/23056 | 0.1960784 | 3.143800 | 3.952869 | 0.0010521 | 0.0059058 | 0.0037967 | PTPN22/COL5A2/SLCO2A1/HFE/IL6/TNFRSF11B/COL5A1/TNFRSF1A/COL1A1/IL2RB | 10 |
| PID_CASPASE_PATHWAY | PID_CASPASE_PATHWAY | PID_CASPASE_PATHWAY | 10/1438 | 51/23056 | 0.1960784 | 3.143800 | 3.952869 | 0.0010521 | 0.0059058 | 0.0037967 | CASP10/CASP8/TFAP2A/GSN/BIRC3/CASP4/CASP1/TNFRSF1A/ARHGDIB/KRT18 | 10 |
| STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | STAMBOLSKY_TARGETS_OF_MUTATED_TP53_DN | 10/1438 | 51/23056 | 0.1960784 | 3.143800 | 3.952869 | 0.0010521 | 0.0059058 | 0.0037967 | SP110/SP100/DDX60/SAMD9/DDX58/TAGLN/IRF9/KRT17/IFI35/MX1 | 10 |
| SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER | SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER | SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER | 14/1438 | 88/23056 | 0.1590909 | 2.550765 | 3.759066 | 0.0010552 | 0.0059058 | 0.0037967 | RASSF5/CEBPD/KLF4/WT1/CD44/PGR/CRIP1/FBN1/CDH13/HOXB13/TNFSF9/THBD/TFAP2C/GATA5 | 14 |
| CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP | CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP | CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | CASQ1/XIRP1/TPM2/CRYAB/NFATC2/SMPX | 6 |
| GOBP_CELLULAR_RESPONSE_TO_GONADOTROPIN_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_GONADOTROPIN_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_GONADOTROPIN_STIMULUS | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | EDN1/INHBA/PLAT/NOTCH1/WT1/GATA6 | 6 |
| GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION | GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION | GOBP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | TGFB2/TGFBR2/NOTCH1/BMP4/NOG/TGFB1 | 6 |
| GOBP_PODOSOME_ASSEMBLY | GOBP_PODOSOME_ASSEMBLY | GOBP_PODOSOME_ASSEMBLY | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | CAPG/CSF2/ARHGEF5/GSN/LCP1/MSN | 6 |
| GOBP_POSITIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | TGFB2/FOXC1/RBM24/PTN/SOX9/GATA6 | 6 |
| GOBP_RENAL_ABSORPTION | GOBP_RENAL_ABSORPTION | GOBP_RENAL_ABSORPTION | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | EDN1/HAS2/AQP3/GSN/AKR1C3/EDNRB | 6 |
| GOBP_RESPONSE_TO_SALT | GOBP_RESPONSE_TO_SALT | GOBP_RESPONSE_TO_SALT | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | ZC3H12A/DAB2/EDN1/RNLS/PITX3/EDNRB | 6 |
| GOBP_TOLL_LIKE_RECEPTOR_3_SIGNALING_PATHWAY | GOBP_TOLL_LIKE_RECEPTOR_3_SIGNALING_PATHWAY | GOBP_TOLL_LIKE_RECEPTOR_3_SIGNALING_PATHWAY | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | PTPN22/TLR3/F2RL1/TNFAIP3/CAV1/COLEC12 | 6 |
| GOBP_TONGUE_DEVELOPMENT | GOBP_TONGUE_DEVELOPMENT | GOBP_TONGUE_DEVELOPMENT | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | CYP26B1/LEF1/GLI3/WNT10B/SIX1/SIX4 | 6 |
| HP_ABNORMAL_MEAN_CORPUSCULAR_HEMOGLOBIN_CONCENTRATION | HP_ABNORMAL_MEAN_CORPUSCULAR_HEMOGLOBIN_CONCENTRATION | HP_ABNORMAL_MEAN_CORPUSCULAR_HEMOGLOBIN_CONCENTRATION | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | CFH/CFI/RHAG/EPB42/PIEZO1/KCNN4 | 6 |
| HP_ANKYLOSIS | HP_ANKYLOSIS | HP_ANKYLOSIS | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | PERP/ADGRG6/TNFRSF11B/FGFR2/MMP2/NOG | 6 |
| HP_CHOROIDAL_NEOVASCULARIZATION | HP_CHOROIDAL_NEOVASCULARIZATION | HP_CHOROIDAL_NEOVASCULARIZATION | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | HMCN1/CFH/EFEMP1/CFI/FBLN5/APOE | 6 |
| HP_VITREORETINOPATHY | HP_VITREORETINOPATHY | HP_VITREORETINOPATHY | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | P3H2/TSPAN12/FZD4/COL9A3/COL18A1/NDP | 6 |
| LEE_NAIVE_T_LYMPHOCYTE | LEE_NAIVE_T_LYMPHOCYTE | LEE_NAIVE_T_LYMPHOCYTE | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | LDLRAP1/INPP4B/ADTRP/EPPK1/PCED1B/NOG | 6 |
| REACTOME_DEFECTIVE_B4GALT7_CAUSES_EDS_PROGEROID_TYPE | REACTOME_DEFECTIVE_B4GALT7_CAUSES_EDS_PROGEROID_TYPE | REACTOME_DEFECTIVE_B4GALT7_CAUSES_EDS_PROGEROID_TYPE | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | AGRN/HSPG2/CSPG4/SDC4/GPC4/BGN | 6 |
| WANG_THOC1_TARGETS_DN | WANG_THOC1_TARGETS_DN | WANG_THOC1_TARGETS_DN | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | GDNF/CLU/NOTCH1/WT1/SOX8/SOX9 | 6 |
| WP_BMP_SIGNALING_IN_EYELID_DEVELOPMENT | WP_BMP_SIGNALING_IN_EYELID_DEVELOPMENT | WP_BMP_SIGNALING_IN_EYELID_DEVELOPMENT | 6/1438 | 20/23056 | 0.3000000 | 4.810014 | 4.396350 | 0.0010566 | 0.0059058 | 0.0037967 | TGFA/FOXC1/SHH/NOTCH1/FGFR2/BMP4 | 6 |
| GOBP_CHOLESTEROL_EFFLUX | GOBP_CHOLESTEROL_EFFLUX | GOBP_CHOLESTEROL_EFFLUX | 12/1438 | 69/23056 | 0.1739130 | 2.788414 | 3.837123 | 0.0010617 | 0.0059058 | 0.0037967 | PPARG/EGF/CAV1/SHH/APOC3/APOA1/SOAT2/NFKBIA/CES1/CETP/ABCA8/APOE | 12 |
| HP_MACULAR_PURPURA | HP_MACULAR_PURPURA | HP_MACULAR_PURPURA | 12/1438 | 69/23056 | 0.1739130 | 2.788414 | 3.837123 | 0.0010617 | 0.0059058 | 0.0037967 | COL3A1/COL5A2/NABP1/CASP10/ITGA2/CD109/STX11/SAMD9/COL5A1/COL1A1/APOE/USP18 | 12 |
| OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | 12/1438 | 69/23056 | 0.1739130 | 2.788414 | 3.837123 | 0.0010617 | 0.0059058 | 0.0037967 | CAPG/JCHAIN/ANXA3/ANXA8/BIRC3/TNFRSF1A/KRT7/KRT8/KRT18/KRT19/HOXB7/PROCR | 12 |
| ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | 12/1438 | 69/23056 | 0.1739130 | 2.788414 | 3.837123 | 0.0010617 | 0.0059058 | 0.0037967 | NIBAN1/GALNT3/SLC7A11/STING1/TPBG/KLF4/NPAS3/NID2/ITPRIPL2/TMC8/CEBPB/KLHL4 | 12 |
| GOBP_LIMBIC_SYSTEM_DEVELOPMENT | GOBP_LIMBIC_SYSTEM_DEVELOPMENT | GOBP_LIMBIC_SYSTEM_DEVELOPMENT | 16/1438 | 108/23056 | 0.1481481 | 2.375316 | 3.694844 | 0.0010618 | 0.0059058 | 0.0037967 | ATP2B4/SRD5A2/DLX1/DLX2/NRP2/ANXA3/LEF1/ID4/GLI3/SEMA3A/NRP1/FGFR2/FOXB1/ALDH1A3/HAP1/SEMA6B | 16 |
| EINAV_INTERFERON_SIGNATURE_IN_CANCER | EINAV_INTERFERON_SIGNATURE_IN_CANCER | EINAV_INTERFERON_SIGNATURE_IN_CANCER | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | IFI44L/SP110/SP100/IRF9/IFI35/MX1/APOBEC3G | 7 |
| GOBP_CD8_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_CD8_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_CD8_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | RUNX3/PTPN22/HFE/HLA-E/CD274/NCKAP1L/RUNX1 | 7 |
| GOBP_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | GOBP_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | GOBP_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | PTPRC/IL7R/HFE/AHR/KLRD1/NCKAP1L/IL4I1 | 7 |
| GOBP_POSITIVE_REGULATION_OF_CHOLESTEROL_EFFLUX | GOBP_POSITIVE_REGULATION_OF_CHOLESTEROL_EFFLUX | GOBP_POSITIVE_REGULATION_OF_CHOLESTEROL_EFFLUX | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | PPARG/CAV1/APOA1/NFKBIA/CES1/ABCA8/APOE | 7 |
| GOBP_POSITIVE_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | CXCL8/EDN1/C3AR1/NCKAP1L/CCR7/C5AR1/RAC2 | 7 |
| GOBP_PROTEIN_AUTOPROCESSING | GOBP_PROTEIN_AUTOPROCESSING | GOBP_PROTEIN_AUTOPROCESSING | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | HJV/PCSK1/SHH/MYRF/CASP4/CASP1/KLK6 | 7 |
| GOBP_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | GOBP_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | GOBP_REGULATION_OF_MACROPHAGE_CHEMOTAXIS | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | CSF1/RARRES2/C3AR1/THBS1/CYP19A1/CCL5/C5AR1 | 7 |
| GOBP_TOOTH_MINERALIZATION | GOBP_TOOTH_MINERALIZATION | GOBP_TOOTH_MINERALIZATION | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | ITGB6/AMTN/ENAM/TFAP2A/FAM20C/SLC24A4/COL1A1 | 7 |
| GOCC_INTEGRATOR_COMPLEX | GOCC_INTEGRATOR_COMPLEX | GOCC_INTEGRATOR_COMPLEX | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | CT45A5/CT45A6/CT45A2/CT45A7/CT45A9/CT45A10/SAGE1 | 7 |
| GROSS_ELK3_TARGETS_UP | GROSS_ELK3_TARGETS_UP | GROSS_ELK3_TARGETS_UP | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | CCN1/EDN1/CAV1/CRYAB/AMIGO2/BMP4/CNN2 | 7 |
| HP_DRUSEN | HP_DRUSEN | HP_DRUSEN | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | RPE65/HMCN1/CFH/EFEMP1/CFI/FBLN5/APOE | 7 |
| HP_HYPOLIPOPROTEINEMIA | HP_HYPOLIPOPROTEINEMIA | HP_HYPOLIPOPROTEINEMIA | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | PPARG/PSMB8/APOC3/APOA1/SLC7A7/CREB3L3/APOE | 7 |
| HP_WRIST_FLEXION_CONTRACTURE | HP_WRIST_FLEXION_CONTRACTURE | HP_WRIST_FLEXION_CONTRACTURE | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | HSPG2/TBX15/PRG4/COL6A3/COL12A1/MMP2/COL6A2 | 7 |
| SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP | SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP | SHARMA_PILOCYTIC_ASTROCYTOMA_LOCATION_UP | 7/1438 | 27/23056 | 0.2592593 | 4.156802 | 4.232977 | 0.0010630 | 0.0059058 | 0.0037967 | RARB/SGMS2/MICB/MSR1/LUM/SIX1/APOBEC3G | 7 |
| HP_ABNORMAL_PARANASAL_SINUS_MORPHOLOGY | HP_ABNORMAL_PARANASAL_SINUS_MORPHOLOGY | HP_ABNORMAL_PARANASAL_SINUS_MORPHOLOGY | 20/1438 | 150/23056 | 0.1333333 | 2.137784 | 3.605662 | 0.0010636 | 0.0059068 | 0.0037973 | FUCA1/PTPN22/FCGR2A/CFAP221/COL5A2/CFI/DNAH5/MCIDAS/CCNO/PSMB8/PSMB9/TAPBP/RUNX2/COL5A1/NFKB2/IL21R/KCNJ2/ELANE/TGFB1/RAC2 | 20 |
| HP_EXERTIONAL_DYSPNEA | HP_EXERTIONAL_DYSPNEA | HP_EXERTIONAL_DYSPNEA | 15/1438 | 98/23056 | 0.1530612 | 2.454089 | 3.720413 | 0.0010702 | 0.0059406 | 0.0038190 | AGRN/TGFB2/NABP1/TGFBR2/LAMB2/MYLK/DOK7/SLC34A2/DSP/CITED2/COL13A1/PYGM/ACTC1/FBN1/GATA6 | 15 |
| HP_ABNORMALITY_OF_THE_ANUS | HP_ABNORMALITY_OF_THE_ANUS | HP_ABNORMALITY_OF_THE_ANUS | 26/1438 | 217/23056 | 0.1198157 | 1.921050 | 3.515838 | 0.0010756 | 0.0059686 | 0.0038370 | MMP23B/HSPG2/TWIST2/COL7A1/CD96/FAT4/FOXC1/RREB1/GLI3/SHH/GDF6/RSPO2/GAS1/NFKB2/FGFR2/MMP1/GRIP1/FREM2/ZIC2/DACT1/SALL1/FOXF1/MEOX1/ELANE/TGFB1/MID1 | 26 |
| VERHAAK_GLIOBLASTOMA_CLASSICAL | VERHAAK_GLIOBLASTOMA_CLASSICAL | VERHAAK_GLIOBLASTOMA_CLASSICAL | 21/1438 | 161/23056 | 0.1304348 | 2.091310 | 3.583811 | 0.0010761 | 0.0059687 | 0.0038371 | PTPN14/LAMB2/FGFR3/ARAP2/SLC4A4/ADAM19/GJA1/PDGFA/ITGB8/EPHB4/TRIP6/PCSK5/GAS1/ITGA7/ACSS3/LRP10/NPAS3/SOX9/MLC1/NDP/KLHL4 | 21 |
| GOBP_INTERLEUKIN_6_PRODUCTION | GOBP_INTERLEUKIN_6_PRODUCTION | GOBP_INTERLEUKIN_6_PRODUCTION | 22/1438 | 172/23056 | 0.1279070 | 2.050781 | 3.567506 | 0.0010774 | 0.0059736 | 0.0038402 | ZC3H12A/PTPN22/RAB7B/IL1A/IL1B/WNT5A/IL1RAP/SPON2/EREG/TLR3/F2RL1/TSLP/TNFAIP3/IL6/CD36/DDX58/NCKAP1L/MBP/IL27RA/KLF2/SIRPA/CEBPB | 22 |
| DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | 11/1438 | 60/23056 | 0.1833333 | 2.939453 | 3.879564 | 0.0010814 | 0.0059932 | 0.0038529 | KCNN3/ACKR3/TNFAIP3/TNS3/MET/SULF1/TCF7L2/VWA5A/IL4R/COL18A1/MN1 | 11 |
| HP_ABNORMAL_HAND_MORPHOLOGY | HP_ABNORMAL_HAND_MORPHOLOGY | HP_ABNORMAL_HAND_MORPHOLOGY | 41/1438 | 397/23056 | 0.1032746 | 1.655840 | 3.399595 | 0.0010838 | 0.0060040 | 0.0038598 | PTCH2/KCNN3/LAMC2/LAMB3/FN1/PPARG/COL7A1/WNT5A/FGFRL1/FGFR3/DOK7/DSP/TFAP2A/RUNX2/GJA1/SAMD9/CAV1/PLAG1/TRPS1/EXT1/TPM2/NOTCH1/FGFR2/MMP1/GLI1/HMGA2/MMP14/BMP4/LTBP2/FOS/FBN1/MMP2/CAVIN1/NOG/ITGB4/SCN1B/BMP2/ARSL/FRMPD4/GPC4/ARHGEF6 | 41 |
| GOBP_RESPONSE_TO_ACID_CHEMICAL | GOBP_RESPONSE_TO_ACID_CHEMICAL | GOBP_RESPONSE_TO_ACID_CHEMICAL | 18/1438 | 129/23056 | 0.1395349 | 2.237216 | 3.634301 | 0.0010932 | 0.0060540 | 0.0038919 | ATP2B4/COL3A1/COL5A2/CPS1/PDGFC/EDN1/CCN2/SPAAR/SIX1/MMP2/NQO1/GIP/COL1A1/KLF2/CRLS1/CEBPB/PNPLA3/COL4A6 | 18 |
| HP_BRACHYDACTYLY | HP_BRACHYDACTYLY | HP_BRACHYDACTYLY | 37/1438 | 348/23056 | 0.1063218 | 1.704698 | 3.416314 | 0.0011010 | 0.0060947 | 0.0039181 | MMP23B/HSPG2/PTCH2/TBX15/NLRP3/ITGB6/TGFBR2/WNT5A/FGFR3/RUNX2/GJA1/CITED2/FAM20C/GLI3/SHH/CSGALNACT1/GDF6/ZFPM2/TRPS1/EXT1/NOTCH1/PAPSS2/FGFR2/ZIC2/BMP4/LTBP2/FBN1/MAF/NOG/KCNJ2/GATA6/RRAS/BMP2/RIN2/GATA5/GPC4/BGN | 37 |
| GOBP_POSITIVE_REGULATION_OF_PROTEOLYSIS | GOBP_POSITIVE_REGULATION_OF_PROTEOLYSIS | GOBP_POSITIVE_REGULATION_OF_PROTEOLYSIS | 39/1438 | 373/23056 | 0.1045576 | 1.676412 | 3.396800 | 0.0011253 | 0.0062268 | 0.0040030 | TNFRSF1B/ZC3H12A/CCN1/S100A10/IFI16/NLRP3/IL1B/CASP10/CASP8/FN1/EPHA4/PPARG/FOXL2/EGF/NKD2/DAB2/CDC20B/SH3RF2/RNF144B/CCN2/PERP/CAV1/CLU/ADAM9/ASPH/TNFSF15/GSN/FAS/NLRP6/CASP4/CASP1/BLID/MMP14/ANXA2/UACA/NUPR1/MBP/APOE/MYH9 | 39 |
| GOBP_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 33/1438 | 300/23056 | 0.1100000 | 1.763672 | 3.433789 | 0.0011297 | 0.0062482 | 0.0040168 | CSF1/TGFB2/ITPKB/COL3A1/HEG1/BCL6/SLIT2/ARHGAP24/F2RL1/DOCK2/ARHGAP18/MET/ARHGEF5/GPR20/NOTCH1/NRP1/SYNPO2L/DNMBP/EPS8L2/ARHGAP42/APOC3/APOA1/PLEKHG6/ARHGDIB/EPS8/IGF1/CGNL1/ITGA3/APOE/TGM2/CYTH4/STARD8/LPAR4 | 33 |
| HP_RECURRENT_LOWER_RESPIRATORY_TRACT_INFECTIONS | HP_RECURRENT_LOWER_RESPIRATORY_TRACT_INFECTIONS | HP_RECURRENT_LOWER_RESPIRATORY_TRACT_INFECTIONS | 19/1438 | 140/23056 | 0.1357143 | 2.175959 | 3.599490 | 0.0011324 | 0.0062584 | 0.0040233 | FCGR2A/FMO3/COL6A3/LAMB2/IL7R/LAMA2/GLI3/COL5A1/COL13A1/NFKB2/EFEMP2/SCNN1A/FBLN5/IL21R/LAT/TNFRSF11A/TGFB1/COL6A2/RAC2 | 19 |
| ONDER_CDH1_TARGETS_1_UP | ONDER_CDH1_TARGETS_1_UP | ONDER_CDH1_TARGETS_1_UP | 19/1438 | 140/23056 | 0.1357143 | 2.175959 | 3.599490 | 0.0011324 | 0.0062584 | 0.0040233 | BCL6/IL1RAP/IL15/AKR1B10/PTGS1/AKR1C3/CD44/PAMR1/EFEMP2/BHLHE41/NUPR1/WIPI1/CD70/CYP4F11/GDF15/TGFB1/APOE/RRAS/KDELR3 | 19 |
| GOBP_CELL_FATE_DETERMINATION | GOBP_CELL_FATE_DETERMINATION | GOBP_CELL_FATE_DETERMINATION | 9/1438 | 43/23056 | 0.2093023 | 3.355824 | 3.987903 | 0.0011398 | 0.0062888 | 0.0040429 | PTCH2/PRRX1/CYP26B1/HES1/HOXA2/EBF2/KLF4/BMP4/GATA6 | 9 |
| GOBP_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY | 9/1438 | 43/23056 | 0.2093023 | 3.355824 | 3.987903 | 0.0011398 | 0.0062888 | 0.0040429 | EPHA4/WNT5A/EDN1/SASH1/ARHGEF5/FZD8/DKK1/FZD4/TNFRSF11A | 9 |
| GOBP_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL | GOBP_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL | GOBP_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL | 9/1438 | 43/23056 | 0.2093023 | 3.355824 | 3.987903 | 0.0011398 | 0.0062888 | 0.0040429 | TRIML2/TRIML1/TRIM38/GSN/IFITM2/IFITM3/TRIM5/NECTIN2/LGALS1 | 9 |
| REACTOME_SIGNALING_BY_RETINOIC_ACID | REACTOME_SIGNALING_BY_RETINOIC_ACID | REACTOME_SIGNALING_BY_RETINOIC_ACID | 9/1438 | 43/23056 | 0.2093023 | 3.355824 | 3.987903 | 0.0011398 | 0.0062888 | 0.0040429 | DHRS3/CRABP2/CYP26B1/RARB/PDK4/AKR1C3/CYP26A1/ALDH1A2/ALDH1A3 | 9 |
| GOMF_CARGO_RECEPTOR_ACTIVITY | GOMF_CARGO_RECEPTOR_ACTIVITY | GOMF_CARGO_RECEPTOR_ACTIVITY | 13/1438 | 79/23056 | 0.1645570 | 2.638404 | 3.762203 | 0.0011415 | 0.0062961 | 0.0040476 | PRG4/LRP1B/ACKR3/ACKR2/STAB1/CFI/DAB2/CD36/MSR1/LOXL2/LOXL4/LRP10/COLEC12 | 13 |
| HP_ABNORMAL_RENAL_PELVIS_MORPHOLOGY | HP_ABNORMAL_RENAL_PELVIS_MORPHOLOGY | HP_ABNORMAL_RENAL_PELVIS_MORPHOLOGY | 26/1438 | 218/23056 | 0.1192661 | 1.912238 | 3.490291 | 0.0011506 | 0.0063433 | 0.0040779 | MMP23B/HSPG2/PTPN22/TBX15/LAMC2/LMOD1/LAMB3/ACTG2/ITGA6/WNT5A/PLD1/FGFR3/TFAP2A/TBX18/FAM20C/GLI3/SHH/FGFR2/SIX1/FOXF1/SOX9/ITGB4/PIEZO2/SIX5/MYL9/GPC4 | 26 |
| GOBP_EMBRYONIC_EYE_MORPHOGENESIS | GOBP_EMBRYONIC_EYE_MORPHOGENESIS | GOBP_EMBRYONIC_EYE_MORPHOGENESIS | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | EFEMP1/RARB/WNT5A/FOXL2/TFAP2A/CITED2/FBN1/ALDH1A3 | 8 |
| GOBP_POSITIVE_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | GOBP_POSITIVE_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | GOBP_POSITIVE_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | PTGS2/KDR/PLK2/ANXA1/JCAD/NRP1/HMOX1/SRPX2 | 8 |
| GOBP_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | GOBP_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | GOBP_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | SERPINE2/IL6/ZNF703/UBASH3B/ADAMTS18/CCL5/C1QTNF1/EMILIN2 | 8 |
| HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | AGT/WNT5A/SPP1/VEGFC/TNFRSF11B/EDNRB/EMP3/ITM2A | 8 |
| HP_ABNORMAL_PLACENTA_MORPHOLOGY | HP_ABNORMAL_PLACENTA_MORPHOLOGY | HP_ABNORMAL_PLACENTA_MORPHOLOGY | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | HSPG2/CFH/FGFR3/CFI/PLAG1/HMGA2/IGF1/FLT1 | 8 |
| HP_FIRST_DEGREE_ATRIOVENTRICULAR_BLOCK | HP_FIRST_DEGREE_ATRIOVENTRICULAR_BLOCK | HP_FIRST_DEGREE_ATRIOVENTRICULAR_BLOCK | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | GJA1/CITED2/SEMA3A/SCNN1A/ACTC1/HCN4/GATA6/SCN1B | 8 |
| KEGG_PRION_DISEASES | KEGG_PRION_DISEASES | KEGG_PRION_DISEASES | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | IL1A/IL1B/C9/IL6/NOTCH1/CCL5/PRNP/NCAM2 | 8 |
| ROZANOV_MMP14_TARGETS_DN | ROZANOV_MMP14_TARGETS_DN | ROZANOV_MMP14_TARGETS_DN | 8/1438 | 35/23056 | 0.2285714 | 3.664773 | 4.068987 | 0.0011616 | 0.0063830 | 0.0041034 | C1orf94/P3H2/CARD16/VWA5A/MT2A/MAF/SDC4/ZNF185 | 8 |
| HP_ABNORMALITY_OF_PULMONARY_CIRCULATION | HP_ABNORMALITY_OF_PULMONARY_CIRCULATION | HP_ABNORMALITY_OF_PULMONARY_CIRCULATION | 22/1438 | 173/23056 | 0.1271676 | 2.038927 | 3.537576 | 0.0011633 | 0.0063830 | 0.0041034 | HSPG2/LAMB2/FGFR3/SLC34A2/GJA1/LAMA2/CCN2/CITED2/CAV1/FLNC/NOTCH1/MYPN/FAS/KRT8/KRT18/ACTC1/FBN1/FOXF1/PIEZO1/COL1A1/GATA6/KCNN4 | 22 |
| BIOCARTA_PLATELETAPP_PATHWAY | BIOCARTA_PLATELETAPP_PATHWAY | BIOCARTA_PLATELETAPP_PATHWAY | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | SERPINE1/PLAT/PLAU/COL4A6/COL4A5 | 5 |
| GOBP_ESTABLISHMENT_OF_LYMPHOCYTE_POLARITY | GOBP_ESTABLISHMENT_OF_LYMPHOCYTE_POLARITY | GOBP_ESTABLISHMENT_OF_LYMPHOCYTE_POLARITY | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | CYP26B1/DOCK2/GSN/CCR7/MYH9 | 5 |
| GOBP_GERMINAL_CENTER_FORMATION | GOBP_GERMINAL_CENTER_FORMATION | GOBP_GERMINAL_CENTER_FORMATION | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | BCL6/TNFAIP3/NFKB2/TNFSF13B/BCL3 | 5 |
| GOBP_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | GOBP_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | SERPINE2/ZNF703/UBASH3B/ADAMTS18/C1QTNF1 | 5 |
| GOBP_NEPHRON_TUBULE_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_NEPHRON_TUBULE_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_NEPHRON_TUBULE_EPITHELIAL_CELL_DIFFERENTIATION | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | OSR1/WWTR1/YAP1/LHX1/LIF | 5 |
| GOBP_REGULATION_OF_PROSTAGLANDIN_SECRETION | GOBP_REGULATION_OF_PROSTAGLANDIN_SECRETION | GOBP_REGULATION_OF_PROSTAGLANDIN_SECRETION | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | PLA2G4A/IL1A/IL1B/EDN1/TNFRSF11A | 5 |
| GOMF_BMP_RECEPTOR_BINDING | GOMF_BMP_RECEPTOR_BINDING | GOMF_BMP_RECEPTOR_BINDING | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | BMP3/BMP6/BMP4/GDF15/BMP2 | 5 |
| HP_ABNORMAL_LYMPHATIC_VESSEL_MORPHOLOGY | HP_ABNORMAL_LYMPHATIC_VESSEL_MORPHOLOGY | HP_ABNORMAL_LYMPHATIC_VESSEL_MORPHOLOGY | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | ADAMTS3/FAT4/FOXF1/PIEZO1/CELSR1 | 5 |
| OZANNE_AP1_TARGETS_UP | OZANNE_AP1_TARGETS_UP | OZANNE_AP1_TARGETS_UP | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | CAPG/SPARC/CD44/MMP1/STAT6 | 5 |
| REACTOME_DEFECTIVE_EXT2_CAUSES_EXOSTOSES_2 | REACTOME_DEFECTIVE_EXT2_CAUSES_EXOSTOSES_2 | REACTOME_DEFECTIVE_EXT2_CAUSES_EXOSTOSES_2 | 5/1438 | 14/23056 | 0.3571429 | 5.726207 | 4.562164 | 0.0011666 | 0.0063830 | 0.0041034 | AGRN/HSPG2/EXT1/SDC4/GPC4 | 5 |
| GOBP_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | GOBP_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | GOBP_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | 16/1438 | 109/23056 | 0.1467890 | 2.353524 | 3.653174 | 0.0011739 | 0.0064204 | 0.0041275 | GBP1/S100A10/LAMB3/ITGA4/FN1/LAMB2/DAB2/RREB1/MICALL2/HAS2/TEK/ITGA8/NRP1/FZD4/APOA1/AXL | 16 |
| FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | 14/1438 | 89/23056 | 0.1573034 | 2.522105 | 3.710579 | 0.0011816 | 0.0064550 | 0.0041497 | TNFRSF1B/GBP2/CD53/PTPRC/COL6A3/DOCK2/PSMB8/MOXD1/GLIPR1/LCP1/IL4R/CCL5/GMFG/RAC2 | 14 |
| GOBP_LEUKOCYTE_HOMEOSTASIS | GOBP_LEUKOCYTE_HOMEOSTASIS | GOBP_LEUKOCYTE_HOMEOSTASIS | 14/1438 | 89/23056 | 0.1573034 | 2.522105 | 3.710579 | 0.0011816 | 0.0064550 | 0.0041497 | ITPKB/CXCL6/SLC7A11/TNFAIP3/IL6/ANXA1/FAS/NCKAP1L/FLT3/TNFSF13B/LAT/TNFSF14/AXL/LGALS2 | 14 |
| KEGG_PROSTATE_CANCER | KEGG_PROSTATE_CANCER | KEGG_PROSTATE_CANCER | 14/1438 | 89/23056 | 0.1573034 | 2.522105 | 3.710579 | 0.0011816 | 0.0064550 | 0.0041497 | SRD5A2/TGFA/LEF1/EGF/PDGFC/PDGFA/TCF7L2/FGFR2/CREB3L1/IGF1/FOXO1/NFKBIA/CREB3L3/PDGFB | 14 |
| HP_NAUSEA_AND_VOMITING | HP_NAUSEA_AND_VOMITING | HP_NAUSEA_AND_VOMITING | 49/1438 | 500/23056 | 0.0980000 | 1.571271 | 3.330815 | 0.0011920 | 0.0065091 | 0.0041845 | ECE1/PTPN22/LAMC2/CFH/LMOD1/LAMB3/NLRP3/ACTG2/ITGA6/COL5A2/CPS1/EPHA4/TGFBR2/MYLK/SPP1/CFI/TLR3/GDNF/HFE/CCN2/TMEM270/SEMA3C/SEMA3D/PON3/CAV1/MET/PODXL/ATP6V0A4/SHH/GAS1/COL5A1/FAS/SAA1/WT1/ALX4/BIRC3/TNFRSF1A/SCNN1A/EDNRB/ZIC2/SLC7A7/COL1A1/ITGB4/RHBDF2/CACNA1A/CYP24A1/PDGFB/COL4A6/COL4A5 | 49 |
| HP_ABNORMALITY_OF_GLOBE_SIZE | HP_ABNORMALITY_OF_GLOBE_SIZE | HP_ABNORMALITY_OF_GLOBE_SIZE | 32/1438 | 289/23056 | 0.1107266 | 1.775322 | 3.420838 | 0.0011943 | 0.0065189 | 0.0041908 | PTCH2/TBX15/NUAK2/RARB/MITF/FOXL2/RREB1/TFAP2A/GJA1/GLI3/TSPAN12/SHH/ASPH/GDF6/RSPO2/GLIS3/NOTCH1/PITX3/FGFR2/ALX4/FZD4/YAP1/GRIP1/FREM2/ZIC2/BMP4/DACT1/FBN1/ALDH1A3/SALL1/PIEZO2/NDP | 32 |
| HP_ABNORMALITY_OF_THE_MAXILLA | HP_ABNORMALITY_OF_THE_MAXILLA | HP_ABNORMALITY_OF_THE_MAXILLA | 18/1438 | 130/23056 | 0.1384615 | 2.220006 | 3.597691 | 0.0011965 | 0.0065286 | 0.0041970 | TWIST2/FGFR3/FAT4/FOXC1/RUNX2/GJA1/COL5A1/FGFR2/EFEMP2/BMP4/FBN1/MMP2/DLX4/KCNJ2/BMP2/ARSL/GPC4/BGN | 18 |
| GOBP_PLATELET_AGGREGATION | GOBP_PLATELET_AGGREGATION | GOBP_PLATELET_AGGREGATION | 12/1438 | 70/23056 | 0.1714286 | 2.748579 | 3.778826 | 0.0012099 | 0.0065964 | 0.0042406 | FN1/SERPINE2/SLC7A11/IL6/VCL/TSPAN32/UBASH3B/ADAMTS18/C1QTNF1/EMILIN2/MYL9/MYH9 | 12 |
| HP_ABNORMALITY_OF_PRIMARY_TEETH | HP_ABNORMALITY_OF_PRIMARY_TEETH | HP_ABNORMALITY_OF_PRIMARY_TEETH | 12/1438 | 70/23056 | 0.1714286 | 2.748579 | 3.778826 | 0.0012099 | 0.0065964 | 0.0042406 | TGFA/COL3A1/FGFR3/ADAMTS2/RUNX2/GJA1/FGFR2/C1S/C1R/WNT10B/PRKD1/KCNJ2 | 12 |
| DESERT_STEM_CELL_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | DESERT_STEM_CELL_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | DESERT_STEM_CELL_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | 28/1438 | 242/23056 | 0.1157025 | 1.855102 | 3.448888 | 0.0012151 | 0.0066218 | 0.0042570 | OLFML3/S100A11/ELF3/CAPG/COL5A2/SERPINE2/SLC12A8/CXCL8/SPP1/DAB2/TNFRSF21/VNN2/ADAM9/TCIM/SULF1/EXT1/TPM2/DKK1/PHLDA2/SERPINH1/ITGA5/HMGA2/DRAM1/POSTN/COL1A1/SOX9/DSG2/KDELR3 | 28 |
| BROWNE_HCMV_INFECTION_1HR_UP | BROWNE_HCMV_INFECTION_1HR_UP | BROWNE_HCMV_INFECTION_1HR_UP | 10/1438 | 52/23056 | 0.1923077 | 3.083342 | 3.878956 | 0.0012309 | 0.0067028 | 0.0043090 | ATP2B4/FGFR3/CXCL8/CXCL1/CXCL2/IL6/SEMA3D/HTR7/TLL2/MMP14 | 10 |
| GOBP_REGULATION_OF_CHOLESTEROL_EFFLUX | GOBP_REGULATION_OF_CHOLESTEROL_EFFLUX | GOBP_REGULATION_OF_CHOLESTEROL_EFFLUX | 10/1438 | 52/23056 | 0.1923077 | 3.083342 | 3.878956 | 0.0012309 | 0.0067028 | 0.0043090 | PPARG/EGF/CAV1/SHH/APOA1/NFKBIA/CES1/CETP/ABCA8/APOE | 10 |
| GOBP_REGULATION_OF_JNK_CASCADE | GOBP_REGULATION_OF_JNK_CASCADE | GOBP_REGULATION_OF_JNK_CASCADE | 19/1438 | 141/23056 | 0.1347518 | 2.160526 | 3.564995 | 0.0012339 | 0.0067166 | 0.0043179 | PTPN22/IL1A/IL1B/WNT5A/TLR3/F2RL1/SH3RF2/TPD52L1/CCN2/SEMA3A/MDFIC/TRAF1/TNFRSF19/DACT1/CCR7/GADD45B/SIRPA/BIRC7/WNT7B | 19 |
| REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2 | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2 | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2 | 17/1438 | 120/23056 | 0.1416667 | 2.271396 | 3.601361 | 0.0012525 | 0.0068149 | 0.0043811 | TWIST2/WWTR1/HES1/NKX3-2/PSMB8/PSMB9/RUNX2/GLI3/YAP1/ITGA5/SMAD6/PSMB10/MAF/COL1A1/SOX9/BMP2/RUNX1 | 17 |
| HP_SARCOMA | HP_SARCOMA | HP_SARCOMA | 21/1438 | 163/23056 | 0.1288344 | 2.065650 | 3.521368 | 0.0012608 | 0.0068576 | 0.0044085 | PTCH2/KCNN3/CASP10/FGFR3/VEGFC/TBX18/FAM20C/PDGFRL/EXT1/FAS/SLC22A18/WT1/PTPRJ/FOXO1/KRT17/COL1A1/PDGFB/SSX1/SSX2/COL4A6/COL4A5 | 21 |
| BOYLAN_MULTIPLE_MYELOMA_D_DN | BOYLAN_MULTIPLE_MYELOMA_D_DN | BOYLAN_MULTIPLE_MYELOMA_D_DN | 13/1438 | 80/23056 | 0.1625000 | 2.605424 | 3.709811 | 0.0012866 | 0.0069897 | 0.0044934 | S100A13/ARAP2/IL7R/CRYBG1/GSN/CD44/AHNAK/CASP1/KRT18/DRAM1/BCL3/CYTH4/LGALS1 | 13 |
| GOBP_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | GOBP_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | GOBP_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING | 13/1438 | 80/23056 | 0.1625000 | 2.605424 | 3.709811 | 0.0012866 | 0.0069897 | 0.0044934 | SCTR/CAP2/ADGRG6/AHR/AQP1/CD36/ADM/EDNRB/THBS1/GIP/SOX9/APOE/GUCY2F | 13 |
| HP_NECK_MUSCLE_WEAKNESS | HP_NECK_MUSCLE_WEAKNESS | HP_NECK_MUSCLE_WEAKNESS | 13/1438 | 80/23056 | 0.1625000 | 2.605424 | 3.709811 | 0.0012866 | 0.0069897 | 0.0044934 | AGRN/DES/COL6A3/LAMB2/DOK7/COL12A1/LAMA2/TPM2/MYPN/COL13A1/CRYAB/MYH2/COL6A2 | 13 |
| HP_WEAKNESS_OF_FACIAL_MUSCULATURE | HP_WEAKNESS_OF_FACIAL_MUSCULATURE | HP_WEAKNESS_OF_FACIAL_MUSCULATURE | 28/1438 | 243/23056 | 0.1152263 | 1.847468 | 3.425226 | 0.0012936 | 0.0070248 | 0.0045160 | AGRN/DES/COL6A3/LAMB2/DOK7/SH3TC2/TFAP2A/COL12A1/GJA1/LAMA2/FLNC/TPM2/GSN/MYPN/COL13A1/BAG3/CRYAB/ITGA7/SIX1/ITGB4/CACNA1A/TGFB1/SIX5/COL6A2/PDGFB/FRMPD4/SRPX2/ARHGEF6 | 28 |
| GOBP_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE | GOBP_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE | GOBP_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE | 26/1438 | 220/23056 | 0.1181818 | 1.894854 | 3.439598 | 0.0013140 | 0.0071329 | 0.0045855 | ADCY10/PTGS2/ITPKB/WNT5A/CLDN1/CRHBP/BMP6/TFAP2A/EDN1/HFE/AQP1/SHH/FABP4/ADCY8/AKR1C3/SYT12/MMP3/ALOX5AP/FOXO1/NFATC4/FOS/MT2A/MT1X/NQO1/PRNP/HMOX1 | 26 |
| FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 35/1438 | 327/23056 | 0.1070336 | 1.716111 | 3.363708 | 0.0013166 | 0.0071440 | 0.0045926 | PDZK1IP1/S100A13/CRABP2/BRINP3/KYNU/GALNT3/LAMB2/RTP4/CLDN1/STK32B/CXCL8/MYO10/MICB/CRYBG1/AKR1B10/CSGALNACT1/CLU/ADAM9/TRPS1/CLIC3/PAPSS2/FGFR2/ADM/PLAAT3/RAB38/YAP1/STYK1/KRT7/OASL/THBS1/ALDH1A3/CES1/IFI35/COL9A3/GGT1 | 35 |
| HP_ASCITES | HP_ASCITES | HP_ASCITES | 15/1438 | 100/23056 | 0.1500000 | 2.405007 | 3.631488 | 0.0013208 | 0.0071640 | 0.0046055 | SP110/ADAMTS3/SPP1/FAT4/HFE/TNFSF15/NOTCH1/WT1/PIEZO1/RHBDF2/PLVAP/IL12RB1/BMP2/RUNX1/USP18 | 15 |
| CHEN_LUNG_CANCER_SURVIVAL | CHEN_LUNG_CANCER_SURVIVAL | CHEN_LUNG_CANCER_SURVIVAL | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | SOD2/ANXA1/ANXA8/KRT7/KRT8/SERPINA1/KRT19 | 7 |
| DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | MEST/ANXA8L1/NNMT/IGFBP6/FOS/ANPEP/TGM2 | 7 |
| DORN_ADENOVIRUS_INFECTION_12HR_UP | DORN_ADENOVIRUS_INFECTION_12HR_UP | DORN_ADENOVIRUS_INFECTION_12HR_UP | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | EPHA2/CCN1/PLK2/ELL2/DDX58/NFKB2/KRT19 | 7 |
| GOBP_EMBRYONIC_HINDLIMB_MORPHOGENESIS | GOBP_EMBRYONIC_HINDLIMB_MORPHOGENESIS | GOBP_EMBRYONIC_HINDLIMB_MORPHOGENESIS | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | OSR1/RARB/SHH/RSPO2/NOTCH1/ALX4/BMP4 | 7 |
| GOBP_REGULATION_OF_OSTEOBLAST_PROLIFERATION | GOBP_REGULATION_OF_OSTEOBLAST_PROLIFERATION | GOBP_REGULATION_OF_OSTEOBLAST_PROLIFERATION | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | CCN1/NPR3/CTHRC1/FGFR2/SOX8/BMP2/MN1 | 7 |
| PLASARI_NFIC_TARGETS_BASAL_UP | PLASARI_NFIC_TARGETS_BASAL_UP | PLASARI_NFIC_TARGETS_BASAL_UP | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | TINAGL1/PLSCR2/PERP/CLU/TNFRSF11B/PPP1R3C/KCNA5 | 7 |
| SHIN_B_CELL_LYMPHOMA_CLUSTER_3 | SHIN_B_CELL_LYMPHOMA_CLUSTER_3 | SHIN_B_CELL_LYMPHOMA_CLUSTER_3 | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | WNT5A/FZD1/HHEX/NFKB2/TNFRSF1A/MAF/TGFB1 | 7 |
| WP_ANGIOTENSIN_II_RECEPTOR_TYPE_1_PATHWAY | WP_ANGIOTENSIN_II_RECEPTOR_TYPE_1_PATHWAY | WP_ANGIOTENSIN_II_RECEPTOR_TYPE_1_PATHWAY | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | AGT/TGFBR2/CCN2/COL1A1/TGFB1/RRAS/IL11 | 7 |
| WP_INTERACTIONS_OF_NATURAL_KILLER_CELLS_IN_PANCREATIC_CANCER | WP_INTERACTIONS_OF_NATURAL_KILLER_CELLS_IN_PANCREATIC_CANCER | WP_INTERACTIONS_OF_NATURAL_KILLER_CELLS_IN_PANCREATIC_CANCER | 7/1438 | 28/23056 | 0.2500000 | 4.008345 | 4.108022 | 0.0013419 | 0.0072524 | 0.0046623 | CD96/CSF2/MICA/MICB/KLRC4-KLRK1/FOXO1/CCL5 | 7 |
| HP_ABNORMALITY_OF_THE_FOREARM | HP_ABNORMALITY_OF_THE_FOREARM | HP_ABNORMALITY_OF_THE_FOREARM | 27/1438 | 232/23056 | 0.1163793 | 1.865954 | 3.418984 | 0.0013494 | 0.0072905 | 0.0046868 | TBX15/CYP26B1/COL5A2/COL7A1/CD96/FGFRL1/FGFR3/TENT5A/GLI3/TMEM270/SAMD9/SHH/EXT1/COLEC10/TPM2/COL27A1/COL5A1/FGFR2/SMAD6/MAF/COL1A1/NOG/PIEZO2/TGFB1/RRAS/COL9A3/BGN | 27 |
| GOBP_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | GOBP_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | GOBP_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 22/1438 | 175/23056 | 0.1257143 | 2.015625 | 3.478317 | 0.0013529 | 0.0073015 | 0.0046939 | CCN1/GFI1/PTGS2/IL1A/IL1B/DAB2/BMP6/ADGRF5/PDGFA/PDK4/ANXA1/AKR1C3/ADM/RAB38/APOC3/APOA1/CES1/GIP/C3/APOE/BMP2/PDGFB | 22 |
| GOBP_NEGATIVE_REGULATION_OF_AXON_EXTENSION | GOBP_NEGATIVE_REGULATION_OF_AXON_EXTENSION | GOBP_NEGATIVE_REGULATION_OF_AXON_EXTENSION | 9/1438 | 44/23056 | 0.2045455 | 3.279555 | 3.903494 | 0.0013547 | 0.0073015 | 0.0046939 | SEMA3B/WNT5A/SEMA5A/SEMA3C/SEMA3A/SEMA3D/NRP1/SEMA6B/MAG | 9 |
| GOBP_POSITIVE_REGULATION_OF_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 9/1438 | 44/23056 | 0.2045455 | 3.279555 | 3.903494 | 0.0013547 | 0.0073015 | 0.0046939 | PTPN22/DDX60/TLR3/F2RL1/CAV1/SLC15A3/OASL/DHX58/IFI35 | 9 |
| HP_DILATATION_OF_THE_CEREBRAL_ARTERY | HP_DILATATION_OF_THE_CEREBRAL_ARTERY | HP_DILATATION_OF_THE_CEREBRAL_ARTERY | 9/1438 | 44/23056 | 0.2045455 | 3.279555 | 3.903494 | 0.0013547 | 0.0073015 | 0.0046939 | TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/COL5A1/FBN1/COL1A1/BGN | 9 |
| MARTIN_NFKB_TARGETS_UP | MARTIN_NFKB_TARGETS_UP | MARTIN_NFKB_TARGETS_UP | 9/1438 | 44/23056 | 0.2045455 | 3.279555 | 3.903494 | 0.0013547 | 0.0073015 | 0.0046939 | VCAM1/CXCL2/SPP1/OSMR/CASP4/C1S/LATS2/FLT1/C3 | 9 |
| WP_VITAMIN_A_AND_CAROTENOID_METABOLISM | WP_VITAMIN_A_AND_CAROTENOID_METABOLISM | WP_VITAMIN_A_AND_CAROTENOID_METABOLISM | 9/1438 | 44/23056 | 0.2045455 | 3.279555 | 3.903494 | 0.0013547 | 0.0073015 | 0.0046939 | DHRS3/RPE65/CRABP2/CYP26B1/RARB/CD36/CYP26A1/ALDH1A2/ALDH1A3 | 9 |
| HP_ABNORMAL_RENAL_CORTEX_MORPHOLOGY | HP_ABNORMAL_RENAL_CORTEX_MORPHOLOGY | HP_ABNORMAL_RENAL_CORTEX_MORPHOLOGY | 25/1438 | 209/23056 | 0.1196172 | 1.917868 | 3.437900 | 0.0013588 | 0.0073208 | 0.0047063 | PTPN22/FCGR2A/CFH/CASP10/FN1/COL7A1/LAMB2/CD96/MME/ARHGAP24/CFI/CRB2/FAS/WT1/MMP1/SLC7A7/MYO1E/MYOCD/ITGA3/ITGB4/C3/APOE/APOL1/TBC1D8B/COL4A5 | 25 |
| HP_ABNORMAL_ARTERIAL_PHYSIOLOGY | HP_ABNORMAL_ARTERIAL_PHYSIOLOGY | HP_ABNORMAL_ARTERIAL_PHYSIOLOGY | 20/1438 | 153/23056 | 0.1307190 | 2.095867 | 3.507611 | 0.0013605 | 0.0073271 | 0.0047103 | PTPN22/TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/SPP1/STING1/NT5E/CITED2/TMEM270/EPHB4/COL5A1/FAS/HTRA1/SCNN1A/ACTC1/FBN1/COL1A1/GATA6 | 20 |
| GOBP_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | GOBP_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | GOBP_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | 17/1438 | 121/23056 | 0.1404959 | 2.252624 | 3.563019 | 0.0013743 | 0.0073956 | 0.0047544 | AGT/BMP10/RARB/EDN1/TBX18/DKK1/WT1/IGF1/BMP4/ACTC1/ALPK3/MYLK3/MYOCD/GATA6/ALPK2/TGFB1/BMP2 | 17 |
| MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP | MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP | MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP | 12/1438 | 71/23056 | 0.1690141 | 2.709867 | 3.721547 | 0.0013748 | 0.0073956 | 0.0047544 | S100A10/CXCL3/MYOZ2/SNCAIP/ADAM9/ANXA1/SRGN/IFITM2/IFITM3/IGFBP6/GADD45B/SAT1 | 12 |
| SESTO_RESPONSE_TO_UV_C8 | SESTO_RESPONSE_TO_UV_C8 | SESTO_RESPONSE_TO_UV_C8 | 12/1438 | 71/23056 | 0.1690141 | 2.709867 | 3.721547 | 0.0013748 | 0.0073956 | 0.0047544 | LTBP1/COL5A2/EPHA4/FGFR3/PTPRK/THBS2/SEMA3C/SERPINE1/PTPRZ1/IL4R/MT2A/ITGA3 | 12 |
| GOBP_LIPID_CATABOLIC_PROCESS | GOBP_LIPID_CATABOLIC_PROCESS | GOBP_LIPID_CATABOLIC_PROCESS | 35/1438 | 328/23056 | 0.1067073 | 1.710879 | 3.344308 | 0.0013878 | 0.0074624 | 0.0047973 | FUCA1/PLA2G4A/HSD11B1/SRD5A2/CYP26B1/IL1B/CPS1/MGLL/AADAC/PLD1/SULT1E1/SPP1/ADTRP/CYP39A1/PLA2G7/AKR1B10/RARRES2/AKR1C3/CYP26A1/PLAAT4/PLAAT3/APOC3/APOA1/HCAR1/LRCOL1/CYP46A1/PLA2G4D/CYP19A1/CES1/LIPG/CYP4F11/APOE/PLA2G4C/CYP24A1/PNPLA3 | 35 |
| BIOCARTA_NFKB_PATHWAY | BIOCARTA_NFKB_PATHWAY | BIOCARTA_NFKB_PATHWAY | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | TNFRSF1B/IL1R1/IL1A/TNFAIP3/TNFRSF1A/NFKBIA | 6 |
| GOBP_LEUKOTRIENE_BIOSYNTHETIC_PROCESS | GOBP_LEUKOTRIENE_BIOSYNTHETIC_PROCESS | GOBP_LEUKOTRIENE_BIOSYNTHETIC_PROCESS | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | PLA2G4A/ALOX5/ALOX5AP/GGTLC3/GGTLC2/GGT1 | 6 |
| GOBP_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | GOBP_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | GOBP_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | ATP2B4/MYOZ2/MYOZ1/SLC24A4/CD22/PRNP | 6 |
| GOBP_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | RUNX3/ZC3H12A/BCL6/ANXA1/IL4R/RUNX1 | 6 |
| GOBP_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | PTGS2/CD34/LUM/THBS1/GATA6/SERPINB7 | 6 |
| GOBP_REGULATION_OF_MYOBLAST_FUSION | GOBP_REGULATION_OF_MYOBLAST_FUSION | GOBP_REGULATION_OF_MYOBLAST_FUSION | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | CD53/IL4R/TNFSF14/GDF15/EHD2/NFATC2 | 6 |
| GOBP_UTERUS_DEVELOPMENT | GOBP_UTERUS_DEVELOPMENT | GOBP_UTERUS_DEVELOPMENT | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | TGFB2/WNT5A/FOXL2/CYP19A1/MYOCD/LHX1 | 6 |
| HU_ANGIOGENESIS_UP | HU_ANGIOGENESIS_UP | HU_ANGIOGENESIS_UP | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | COL7A1/HECW1/SEMA3C/FOS/THBS1/ITGB4 | 6 |
| KANG_CISPLATIN_RESISTANCE_UP | KANG_CISPLATIN_RESISTANCE_UP | KANG_CISPLATIN_RESISTANCE_UP | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | TFPI/TENT5A/IGFBP6/AHNAK2/JUP/RAC2 | 6 |
| REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION | REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION | REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | LGR6/RSPO3/FZD6/RSPO2/FZD8/FZD4 | 6 |
| SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | FGFR3/FST/EDN1/PNOC/FGFR2/MBP | 6 |
| SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1A | SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1A | SUZUKI_RESPONSE_TO_TSA_AND_DECITABINE_1A | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | S100A10/PTGS2/KYNU/COL6A3/LAMA2/PYROXD2 | 6 |
| WP_GALANIN_RECEPTOR_PATHWAY | WP_GALANIN_RECEPTOR_PATHWAY | WP_GALANIN_RECEPTOR_PATHWAY | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | PPARG/TFAP2A/IL6/YAP1/FOS/KRT19 | 6 |
| WP_INTERACTIONS_BETWEEN_LOXL4_AND_OXIDATIVE_STRESS_PATHWAY | WP_INTERACTIONS_BETWEEN_LOXL4_AND_OXIDATIVE_STRESS_PATHWAY | WP_INTERACTIONS_BETWEEN_LOXL4_AND_OXIDATIVE_STRESS_PATHWAY | 6/1438 | 21/23056 | 0.2857143 | 4.580966 | 4.234186 | 0.0014018 | 0.0074966 | 0.0048193 | FN1/DDR1/LOXL4/NQO1/TGFB1/BMP2 | 6 |
| CUI_TCF21_TARGETS_UP | CUI_TCF21_TARGETS_UP | CUI_TCF21_TARGETS_UP | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | CFH/FAP/COL3A1/EPHA4/PTN/LUM/CLDN6/COL6A2 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | KDR/SEMA5A/TNFAIP3/SERPINE1/ANGPT1/TEK/ICAM1/IL11 | 8 |
| GOBP_PEPTIDE_CROSS_LINKING | GOBP_PEPTIDE_CROSS_LINKING | GOBP_PEPTIDE_CROSS_LINKING | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | COL3A1/FN1/DSP/ANXA1/THBS1/EPB42/TGM2/BGN | 8 |
| GOBP_SIGNALING_RECEPTOR_LIGAND_PRECURSOR_PROCESSING | GOBP_SIGNALING_RECEPTOR_LIGAND_PRECURSOR_PROCESSING | GOBP_SIGNALING_RECEPTOR_LIGAND_PRECURSOR_PROCESSING | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | ECE1/DPP4/MME/PCSK1/PLA2G7/PCSK5/CASP1/BACE2 | 8 |
| GOMF_CHEMOATTRACTANT_ACTIVITY | GOMF_CHEMOATTRACTANT_ACTIVITY | GOMF_CHEMOATTRACTANT_ACTIVITY | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | WNT5A/VEGFC/GDNF/GPNMB/COLEC10/BMP4/CCL5/PDGFB | 8 |
| HP_ABNORMAL_ST_SEGMENT | HP_ABNORMAL_ST_SEGMENT | HP_ABNORMAL_ST_SEGMENT | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | TNNC1/CITED2/SEMA3A/SCNN1A/ACTC1/HCN4/GATA6/SCN1B | 8 |
| HP_RECURRENT_INFECTION_OF_THE_GASTROINTESTINAL_TRACT | HP_RECURRENT_INFECTION_OF_THE_GASTROINTESTINAL_TRACT | HP_RECURRENT_INFECTION_OF_THE_GASTROINTESTINAL_TRACT | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | GFI1/SP110/NFKB2/FLT1/IRF9/NFKBIA/IL21R/ELANE | 8 |
| HP_SEVERE_INFECTION | HP_SEVERE_INFECTION | HP_SEVERE_INFECTION | 8/1438 | 36/23056 | 0.2222222 | 3.562973 | 3.969145 | 0.0014129 | 0.0075325 | 0.0048424 | PTPRC/IL7R/LAT/TMC8/ELANE/CD70/TGFB1/RAC2 | 8 |
| HP_ABNORMALITY_OF_THE_THYROID_GLAND | HP_ABNORMALITY_OF_THE_THYROID_GLAND | HP_ABNORMALITY_OF_THE_THYROID_GLAND | 45/1438 | 453/23056 | 0.0993377 | 1.592720 | 3.286017 | 0.0014135 | 0.0075331 | 0.0048428 | MMP23B/ECE1/HSPG2/FUCA1/CASP10/THRB/TGFBR2/IL7R/GDNF/PCSK1/RREB1/HFE/SIM1/SASH1/GLI3/TMEM270/SEMA3C/SEMA3D/SLC26A4/SHH/PLAG1/GLIS3/GAS1/TNFSF15/FAS/SAA1/ALX4/BIRC3/C1S/HMGA2/HPD/EDNRB/ZIC2/MMP14/BMP4/DACT1/SIX1/SALL1/MMP2/PIEZO1/GATA6/PLVAP/IL12RB1/APOE/PDGFB | 45 |
| GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 18/1438 | 132/23056 | 0.1363636 | 2.186370 | 3.525463 | 0.0014281 | 0.0076023 | 0.0048872 | ZC3H12A/PTGS2/RASSF5/WWTR1/GLI3/CD36/MDFIC/SHH/ANGPT1/BAG3/YAP1/LATS2/PRKD1/BMP4/JUP/TGFB1/LIF/CARD10 | 18 |
| DOANE_BREAST_CANCER_ESR1_UP | DOANE_BREAST_CANCER_ESR1_UP | DOANE_BREAST_CANCER_ESR1_UP | 16/1438 | 111/23056 | 0.1441441 | 2.311118 | 3.571194 | 0.0014282 | 0.0076023 | 0.0048872 | CYBRD1/KCNE4/MLPH/SEMA3B/STK32B/INPP4B/SEMA3C/PGR/SCNN1A/GPRC5A/RND1/KRT18/CRIP1/CA12/GDF15/CELSR1 | 16 |
| HP_MITRAL_VALVE_PROLAPSE | HP_MITRAL_VALVE_PROLAPSE | HP_MITRAL_VALVE_PROLAPSE | 16/1438 | 111/23056 | 0.1441441 | 2.311118 | 3.571194 | 0.0014282 | 0.0076023 | 0.0048872 | TGFB2/COL3A1/COL5A2/TGFBR2/PLD1/TENT5A/TMEM270/TPM2/COL5A1/MYPN/VWF/MMP14/FBN1/HCN4/MMP2/COL1A1 | 16 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | GOBP_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | GOBP_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 23/1438 | 187/23056 | 0.1229947 | 1.972020 | 3.442125 | 0.0014321 | 0.0076202 | 0.0048988 | GFI1/EPHA4/SEMA3B/WNT5A/HES1/SLIT2/ARHGAP24/SPP1/SEMA5A/DAB2/SEMA3C/SEMA3A/SEMA3D/NRP1/DKK1/YAP1/NFATC4/ITGA3/MBP/SEMA6B/MAG/APOE/PRNP | 23 |
| GOBP_PLASMA_LIPOPROTEIN_PARTICLE_CLEARANCE | GOBP_PLASMA_LIPOPROTEIN_PARTICLE_CLEARANCE | GOBP_PLASMA_LIPOPROTEIN_PARTICLE_CLEARANCE | 10/1438 | 53/23056 | 0.1886792 | 3.025166 | 3.806805 | 0.0014337 | 0.0076256 | 0.0049022 | LDLRAP1/CD36/MSR1/APOC3/APOA1/SOAT2/ANXA2/LIPG/APOE/HMOX1 | 10 |
| GOBP_REGULATION_OF_METAL_ION_TRANSPORT | GOBP_REGULATION_OF_METAL_ION_TRANSPORT | GOBP_REGULATION_OF_METAL_ION_TRANSPORT | 41/1438 | 403/23056 | 0.1017370 | 1.631188 | 3.296874 | 0.0014418 | 0.0076659 | 0.0049282 | CASQ1/PTGS2/ATP2B4/AGT/OSR1/KCNE4/SERPINE2/MYLK/HES1/EGF/TRPC3/ADRB2/HFE/TRDN/UTRN/HECW1/CAV1/STC1/TMC1/PTPN3/PLPP4/LRRC55/AHNAK/UBASH3B/KCNA5/PRKD1/BDKRB1/GRAMD2A/RRAD/TRPV2/CCL5/HAP1/KCNJ2/SCN1B/FXYD5/KCNN4/CACNG6/PRNP/REM1/JPH2/PDGFB | 41 |
| FALVELLA_SMOKERS_WITH_LUNG_CANCER | FALVELLA_SMOKERS_WITH_LUNG_CANCER | FALVELLA_SMOKERS_WITH_LUNG_CANCER | 13/1438 | 81/23056 | 0.1604938 | 2.573259 | 3.658214 | 0.0014467 | 0.0076831 | 0.0049392 | ITGB6/AHRR/RNF144B/SOD2/MICALL2/SERPINE1/MET/STC1/MMP1/C1S/SERPINB2/HAS1/APOL6 | 13 |
| HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | 13/1438 | 81/23056 | 0.1604938 | 2.573259 | 3.658214 | 0.0014467 | 0.0076831 | 0.0049392 | CFH/INPP4B/NPR3/F2RL1/CRHBP/ADGRG6/COL5A1/BAG3/PPM1H/HMGA2/FOXO1/TPM1/CAVIN1 | 13 |
| HP_ABNORMAL_ATRIOVENTRICULAR_CONDUCTION | HP_ABNORMAL_ATRIOVENTRICULAR_CONDUCTION | HP_ABNORMAL_ATRIOVENTRICULAR_CONDUCTION | 13/1438 | 81/23056 | 0.1604938 | 2.573259 | 3.658214 | 0.0014467 | 0.0076831 | 0.0049392 | DES/GJA1/TRDN/CITED2/SEMA3A/SCNN1A/MMP14/ACTC1/HCN4/MMP2/KCNJ2/GATA6/SCN1B | 13 |
| FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | 35/1438 | 329/23056 | 0.1063830 | 1.705679 | 3.324973 | 0.0014623 | 0.0077628 | 0.0049905 | SYNC/MLPH/ITGB5/RBM47/CXCL8/CXCL5/INPP4B/MYO10/GALNT10/FOXC1/TFAP2A/TPBG/SOD2/SEMA3C/SLC22A18/ADM/BBOX1/CD44/AHNAK/MPZL2/SCNN1A/YBX3/RND1/KRT8/KRT18/CRIP1/CA12/BCL2A1/NQO1/GDF15/PRNP/CEBPB/CELSR1/MID1/MSN | 35 |
| GAVIN_FOXP3_TARGETS_CLUSTER_P4 | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | 15/1438 | 101/23056 | 0.1485149 | 2.381195 | 3.587825 | 0.0014636 | 0.0077634 | 0.0049908 | TNFRSF18/TNFRSF4/TNFRSF9/TNFRSF1B/NIBAN1/CAPG/LYPD6B/MYO10/STX11/MAP3K8/NRP1/SLC16A5/GADD45B/APOL3/IL2RB | 15 |
| GOBP_MUSCLE_HYPERTROPHY | GOBP_MUSCLE_HYPERTROPHY | GOBP_MUSCLE_HYPERTROPHY | 15/1438 | 101/23056 | 0.1485149 | 2.381195 | 3.587825 | 0.0014636 | 0.0077634 | 0.0049908 | ERRFI1/TNFRSF1B/TRIM63/ATP2B4/AGT/BMP10/PPARG/TRPC3/EDN1/NOTCH1/TNFRSF1A/IGF1/FOXO1/GATA6/GATA5 | 15 |
| HP_APLASIA_HYPOPLASIA_OF_THE_EAR | HP_APLASIA_HYPOPLASIA_OF_THE_EAR | HP_APLASIA_HYPOPLASIA_OF_THE_EAR | 21/1438 | 165/23056 | 0.1272727 | 2.040612 | 3.459813 | 0.0014720 | 0.0077974 | 0.0050127 | MMP23B/HSPG2/TBX15/TWIST2/FGFR3/FAT4/TFAP2A/EDN1/SIM1/HOXA2/GLI3/SLC26A4/RSPO2/FGFR2/DACT1/SIX1/SALL1/MAF/ITGB4/SIX5/BMP2 | 21 |
| GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION | 14/1438 | 91/23056 | 0.1538462 | 2.466674 | 3.615557 | 0.0014728 | 0.0077974 | 0.0050127 | TNFRSF21/TNFAIP3/GPNMB/SHH/IDO1/CD274/PDCD1LG2/SFTPD/LRRC32/BMP4/IL4I1/PRNP/SDC4/CEBPB | 14 |
| GOCC_CLATHRIN_COATED_ENDOCYTIC_VESICLE | GOCC_CLATHRIN_COATED_ENDOCYTIC_VESICLE | GOCC_CLATHRIN_COATED_ENDOCYTIC_VESICLE | 14/1438 | 91/23056 | 0.1538462 | 2.466674 | 3.615557 | 0.0014728 | 0.0077974 | 0.0050127 | LDLRAP1/TGFA/WNT5A/EPGN/EREG/BTC/EGF/IL7R/HBEGF/ADRB2/SFTPD/FZD4/MYO1E/APOE | 14 |
| HP_EXTERNAL_EAR_MALFORMATION | HP_EXTERNAL_EAR_MALFORMATION | HP_EXTERNAL_EAR_MALFORMATION | 14/1438 | 91/23056 | 0.1538462 | 2.466674 | 3.615557 | 0.0014728 | 0.0077974 | 0.0050127 | FGFR3/ADAMTS3/FAT4/EDN1/GJA1/SHH/FGFR2/GRIP1/FREM2/ZIC2/DACT1/SIX1/SALL1/SIX5 | 14 |
| REACTOME_PEPTIDE_HORMONE_METABOLISM | REACTOME_PEPTIDE_HORMONE_METABOLISM | REACTOME_PEPTIDE_HORMONE_METABOLISM | 14/1438 | 91/23056 | 0.1538462 | 2.466674 | 3.615557 | 0.0014728 | 0.0077974 | 0.0050127 | AGT/DPP4/MME/PCSK1/PLA2G7/INHBA/KLF4/TCF7L2/IGF1/ANPEP/CES1/GIP/CGB5/CGB8 | 14 |
| GOMF_PEPTIDE_RECEPTOR_ACTIVITY | GOMF_PEPTIDE_RECEPTOR_ACTIVITY | GOMF_PEPTIDE_RECEPTOR_ACTIVITY | 20/1438 | 154/23056 | 0.1298701 | 2.082257 | 3.475428 | 0.0014740 | 0.0078005 | 0.0050147 | SCTR/ACKR3/VIPR1/ACKR2/CCR3/NPR3/F2RL1/HCRTR2/OGFRL1/GPR37/NPY4R2/NLRP6/CCKBR/EDNRB/BDKRB1/GLP2R/CCR7/FPR1/CYSLTR1/GUCY2F | 20 |
| DELACROIX_RAR_BOUND_ES | DELACROIX_RAR_BOUND_ES | DELACROIX_RAR_BOUND_ES | 46/1438 | 467/23056 | 0.0985011 | 1.579305 | 3.261906 | 0.0014946 | 0.0079066 | 0.0050829 | DHRS3/C1orf54/GPA33/TRIM17/EVA1A/FN1/ACKR3/BHLHE40/RARB/SHISA5/MME/ZFYVE28/SPP1/GASK1B/SLC12A7/HBEGF/RREB1/TCP11/GJA1/CCN2/STRA8/RBPMS/AQP3/C9orf152/NACC2/TCF7L2/IFITM2/GPRC5A/DNAJC22/KRT79/ITGA5/GLI1/ZIC2/RAB20/BMP4/SLC28A1/MSLN/HOXB13/SOCS3/MBP/KLF2/BCL3/CD37/RIN2/KIAA1755/GPC4 | 46 |
| HELLER_HDAC_TARGETS_DN | HELLER_HDAC_TARGETS_DN | HELLER_HDAC_TARGETS_DN | 32/1438 | 293/23056 | 0.1092150 | 1.751086 | 3.337051 | 0.0014957 | 0.0079093 | 0.0050846 | S100A11/KCNN3/PTPRC/CNIH3/RASGRP3/ITGB5/FGFR3/SLC7A11/IQGAP2/CCDC69/GJA1/TNS3/SULF1/CCN4/FAS/BAG3/HBD/CD44/SERPINH1/ARHGDIB/SELPLG/DNAJC15/IL21R/PSMB10/MAF/SLC47A1/FMNL1/MBP/EMP3/CEBPB/HMOX1/APOBEC3G | 32 |
| GOBP_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE | 17/1438 | 122/23056 | 0.1393443 | 2.234160 | 3.525052 | 0.0015060 | 0.0079549 | 0.0051140 | TNFRSF4/PTPN22/PTPRC/NLRP3/IL1R1/IL1B/WNT5A/SPON2/F2RL1/MZB1/HLA-E/IL6/CD36/DDX58/STAT6/IL4R/TGFB1 | 17 |
| GOMF_HORMONE_ACTIVITY | GOMF_HORMONE_ACTIVITY | GOMF_HORMONE_ACTIVITY | 17/1438 | 122/23056 | 0.1393443 | 2.234160 | 3.525052 | 0.0015060 | 0.0079549 | 0.0051140 | C1QTNF12/EDN2/AGT/BMP10/UCN2/OSTN/EDN1/INHBA/STC1/PNOC/ADM/SPX/IGF1/FBN1/GIP/METRNL/CGB7 | 17 |
| HP_ABNORMALITY_OF_THE_SHOULDER_GIRDLE_MUSCULATURE | HP_ABNORMALITY_OF_THE_SHOULDER_GIRDLE_MUSCULATURE | HP_ABNORMALITY_OF_THE_SHOULDER_GIRDLE_MUSCULATURE | 17/1438 | 122/23056 | 0.1393443 | 2.234160 | 3.525052 | 0.0015060 | 0.0079549 | 0.0051140 | AGRN/COL6A3/LAMB2/DOK7/SH3TC2/COL12A1/CSGALNACT1/TRPS1/TPM2/MYPN/COL13A1/ITGA7/FBN1/MYH2/SGCA/KCNJ2/COL6A2 | 17 |
| GOBP_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | GOBP_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | GOBP_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 38/1438 | 367/23056 | 0.1035422 | 1.660132 | 3.287838 | 0.0015417 | 0.0081400 | 0.0052330 | PTGS2/PTPRC/AGT/IL1A/IL1B/ITGA6/SP100/ACKR3/GDNF/CSF2/TPD52L1/VNN1/TNFAIP3/SOD2/INHBA/SERPINE1/CAV1/CLU/TRAF1/NACC2/NRP1/FAS/ITPRIP/TCF7L2/CD44/CREB3L1/YAP1/YBX3/IGF1/NFATC4/BMP4/THBS1/TNFRSF12A/NUPR1/NOG/TMC8/ICAM1/HMOX1 | 38 |
| GOCC_CLATHRIN_COATED_ENDOCYTIC_VESICLE_MEMBRANE | GOCC_CLATHRIN_COATED_ENDOCYTIC_VESICLE_MEMBRANE | GOCC_CLATHRIN_COATED_ENDOCYTIC_VESICLE_MEMBRANE | 12/1438 | 72/23056 | 0.1666667 | 2.672230 | 3.665251 | 0.0015579 | 0.0082200 | 0.0052843 | LDLRAP1/TGFA/WNT5A/EPGN/EREG/BTC/EGF/IL7R/HBEGF/ADRB2/FZD4/APOE | 12 |
| HP_ABNORMALITY_OF_THE_URETER | HP_ABNORMALITY_OF_THE_URETER | HP_ABNORMALITY_OF_THE_URETER | 34/1438 | 318/23056 | 0.1069182 | 1.714261 | 3.307870 | 0.0015580 | 0.0082200 | 0.0052843 | HSPG2/PTPN22/LAMC2/LMOD1/LAMB3/ACTG2/ITGA6/RARB/MYLK/PLD1/FGFR3/RREB1/TBX18/FAM20C/GLI3/TMEM270/TRPS1/EXT1/FGFR2/EFEMP2/GLI1/DACT1/SIX1/FBLN5/SALL1/FOXF1/LHX1/ITGB4/PIEZO2/GATA6/SCN1B/SIX5/COL18A1/GPC4 | 34 |
| GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION | 16/1438 | 112/23056 | 0.1428571 | 2.290483 | 3.530863 | 0.0015718 | 0.0082895 | 0.0053291 | ATP2B4/BMP10/SP100/PPARG/SLIT2/SEMA3A/STC1/EPPK1/KLF4/NOTCH1/MMRN2/THBS1/JUP/TGFB1/APOE/CARD10 | 16 |
| GOMF_SYMPORTER_ACTIVITY | GOMF_SYMPORTER_ACTIVITY | GOMF_SYMPORTER_ACTIVITY | 19/1438 | 144/23056 | 0.1319444 | 2.115515 | 3.463216 | 0.0015862 | 0.0083588 | 0.0053736 | SLC1A7/SLC12A8/SLC34A2/SLC4A4/SLC12A7/SLC6A7/SLC22A1/SLC16A12/SLC22A18/SLC5A12/SLC15A3/SLC6A13/SLC38A4/SLC10A2/SLC24A4/SLC28A1/SLC16A5/SLC16A3/SLC6A16 | 19 |
| WP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING | WP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING | WP_NEUROINFLAMMATION_AND_GLUTAMATERGIC_SIGNALING | 19/1438 | 144/23056 | 0.1319444 | 2.115515 | 3.463216 | 0.0015862 | 0.0083588 | 0.0053736 | TNFRSF1B/TGFB2/IL1R1/IL1A/IL1B/TGFBR2/IL6/ADCY8/NFKB2/TNFRSF1A/STAT6/IGF1/FOS/IL4R/SOCS3/SLC7A10/TGFB1/LIF/IL13RA1 | 19 |
| GOBP_BODY_MORPHOGENESIS | GOBP_BODY_MORPHOGENESIS | GOBP_BODY_MORPHOGENESIS | 9/1438 | 45/23056 | 0.2000000 | 3.206676 | 3.821478 | 0.0016010 | 0.0084307 | 0.0054198 | PHLDB2/LEF1/ASPH/DKK1/MMP2/CRISPLD2/COL1A1/NOG/RRAS | 9 |
| GOBP_NEUROINFLAMMATORY_RESPONSE | GOBP_NEUROINFLAMMATORY_RESPONSE | GOBP_NEUROINFLAMMATORY_RESPONSE | 9/1438 | 45/23056 | 0.2000000 | 3.206676 | 3.821478 | 0.0016010 | 0.0084307 | 0.0054198 | TNFRSF1B/PTGS2/PTPRC/IL1B/IL6/ADCY8/MMP3/IGF1/NUPR1 | 9 |
| KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | 24/1438 | 200/23056 | 0.1200000 | 1.924006 | 3.384883 | 0.0016048 | 0.0084474 | 0.0054306 | GBP3/GBP1/VCAM1/LAMC2/NIBAN1/ITGB6/THRB/GRAMD2B/COLEC10/MMRN2/ACSL5/SAA1/CARD16/SLC46A3/SERPINA6/ALDH1A3/NUPR1/RRAD/PSMB10/CRISPLD2/DHX58/IFI35/TNFSF14/PLA2G4C | 24 |
| ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP | ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP | ODONNELL_TARGETS_OF_MYC_AND_TFRC_UP | 13/1438 | 82/23056 | 0.1585366 | 2.541877 | 3.607387 | 0.0016230 | 0.0085401 | 0.0054901 | MR1/TMEM156/PTGS1/ALOX5/CD44/PLAAT4/C1RL/GLIPR1/IL4R/LLGL2/CD37/SAT1/IL13RA1 | 13 |
| GOBP_BONE_RESORPTION | GOBP_BONE_RESORPTION | GOBP_BONE_RESORPTION | 11/1438 | 63/23056 | 0.1746032 | 2.799479 | 3.688701 | 0.0016377 | 0.0086007 | 0.0055291 | S1PR1/SPP1/ADRB2/TNFAIP3/IL6/PDK4/EXT1/TNFRSF11B/UBASH3B/SIGLEC15/TNFRSF11A | 11 |
| HP_HYPERCHOLESTEROLEMIA | HP_HYPERCHOLESTEROLEMIA | HP_HYPERCHOLESTEROLEMIA | 11/1438 | 63/23056 | 0.1746032 | 2.799479 | 3.688701 | 0.0016377 | 0.0086007 | 0.0055291 | LDLRAP1/PPARG/CAV1/APOC3/SLC7A7/PYGL/FOS/CETP/CAVIN1/CREB3L3/APOE | 11 |
| HP_VERTEBRAL_FUSION | HP_VERTEBRAL_FUSION | HP_VERTEBRAL_FUSION | 11/1438 | 63/23056 | 0.1746032 | 2.799479 | 3.688701 | 0.0016377 | 0.0086007 | 0.0055291 | PTCH2/FN1/FGFRL1/SH3TC2/BMPER/GDF6/DKK1/FGFR2/MEOX1/NOG/GPC4 | 11 |
| INGRAM_SHH_TARGETS_DN | INGRAM_SHH_TARGETS_DN | INGRAM_SHH_TARGETS_DN | 11/1438 | 63/23056 | 0.1746032 | 2.799479 | 3.688701 | 0.0016377 | 0.0086007 | 0.0055291 | MME/EREG/TGFBI/SPARC/CAV2/PTN/CLU/DRAM1/AJUBA/COL1A1/C3 | 11 |
| LINDSTEDT_DENDRITIC_CELL_MATURATION_C | LINDSTEDT_DENDRITIC_CELL_MATURATION_C | LINDSTEDT_DENDRITIC_CELL_MATURATION_C | 11/1438 | 63/23056 | 0.1746032 | 2.799479 | 3.688701 | 0.0016377 | 0.0086007 | 0.0055291 | S1PR1/NID1/CAPG/MGLL/ANXA3/TNFRSF11B/COL14A1/FLT3/FOXO1/IL4R/TNFRSF11A | 11 |
| TOOKER_GEMCITABINE_RESISTANCE_DN | TOOKER_GEMCITABINE_RESISTANCE_DN | TOOKER_GEMCITABINE_RESISTANCE_DN | 17/1438 | 123/23056 | 0.1382114 | 2.215996 | 3.487453 | 0.0016482 | 0.0086446 | 0.0055573 | MLPH/WWTR1/FGFR3/ANXA3/SLC7A11/PDGFC/CLU/PAPSS2/SERPINH1/GPRC5A/IGFBP6/SMAD6/CAVIN1/SOX9/CEBPB/CYP24A1/LGALS1 | 17 |
| GOBP_RESPONSE_TO_TOXIC_SUBSTANCE | GOBP_RESPONSE_TO_TOXIC_SUBSTANCE | GOBP_RESPONSE_TO_TOXIC_SUBSTANCE | 28/1438 | 247/23056 | 0.1133603 | 1.817549 | 3.331681 | 0.0016533 | 0.0086446 | 0.0055573 | PTGS2/CPS1/CLDN1/SOD3/ABCG2/SLC7A11/SOD2/AHR/CD36/PON3/AKR1B10/TRPM6/PTGS1/SLC22A18/HBD/ALOX5AP/FOS/FBLN5/NUPR1/CES1/MT2A/MT1X/NQO1/SLC47A1/CCL5/GATA6/MBP/APOE | 28 |
| SHEPARD_BMYB_MORPHOLINO_UP | SHEPARD_BMYB_MORPHOLINO_UP | SHEPARD_BMYB_MORPHOLINO_UP | 25/1438 | 212/23056 | 0.1179245 | 1.890729 | 3.360327 | 0.0016593 | 0.0086446 | 0.0055573 | CRABP2/CAMK1G/CYP26B1/CASP8/OSBPL10/FST/GMPR/RNF144B/HFE/SASH1/FBXO32/EPPK1/AIF1L/PHLDA2/MS4A4A/KRT18/FOS/ANXA2/MMP2/SOCS3/MBP/CRLS1/BMP2/GPC4/BGN | 25 |
| BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER | BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER | BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | TGFA/TGFBR2/MET/DACT1/TGFB1 | 5 |
| GOBP_EMBRYONIC_SKELETAL_JOINT_DEVELOPMENT | GOBP_EMBRYONIC_SKELETAL_JOINT_DEVELOPMENT | GOBP_EMBRYONIC_SKELETAL_JOINT_DEVELOPMENT | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | WNT9A/OSR1/EXT1/BMP4/NOG | 5 |
| GOBP_METANEPHRIC_MESENCHYME_DEVELOPMENT | GOBP_METANEPHRIC_MESENCHYME_DEVELOPMENT | GOBP_METANEPHRIC_MESENCHYME_DEVELOPMENT | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | OSR1/SHH/WT1/SIX1/SIX4 | 5 |
| GOBP_METANEPHRIC_RENAL_VESICLE_MORPHOGENESIS | GOBP_METANEPHRIC_RENAL_VESICLE_MORPHOGENESIS | GOBP_METANEPHRIC_RENAL_VESICLE_MORPHOGENESIS | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | GDNF/BMP4/SALL1/LHX1/LIF | 5 |
| GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | GOBP_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | KDR/SEMA5A/FGF18/MET/PRKD1 | 5 |
| GOBP_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | GOBP_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | PDGFA/WT1/BMP4/SERPINB7/PDGFB | 5 |
| GOBP_REGULATION_OF_MEMBRANE_INVAGINATION | GOBP_REGULATION_OF_MEMBRANE_INVAGINATION | GOBP_REGULATION_OF_MEMBRANE_INVAGINATION | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | ITGA2/F2RL1/CD36/NCKAP1L/C3 | 5 |
| GOBP_T_HELPER_2_CELL_DIFFERENTIATION | GOBP_T_HELPER_2_CELL_DIFFERENTIATION | GOBP_T_HELPER_2_CELL_DIFFERENTIATION | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | NLRP3/BCL6/ANXA1/IL4R/BCL3 | 5 |
| HAHTOLA_CTCL_PATHOGENESIS | HAHTOLA_CTCL_PATHOGENESIS | HAHTOLA_CTCL_PATHOGENESIS | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | TXK/IL7R/MS4A4A/CCL5/IL2RB | 5 |
| HP_ESOPHAGEAL_STRICTURE | HP_ESOPHAGEAL_STRICTURE | HP_ESOPHAGEAL_STRICTURE | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | LAMC2/LAMB3/COL7A1/SAMD9/MMP1 | 5 |
| HP_GLOMERULAR_DEPOSITS | HP_GLOMERULAR_DEPOSITS | HP_GLOMERULAR_DEPOSITS | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | CFH/COL7A1/MME/MMP1/COL4A5 | 5 |
| LEE_SP4_THYMOCYTE | LEE_SP4_THYMOCYTE | LEE_SP4_THYMOCYTE | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | IFI44L/SERPINE2/IRAK2/CLDN1/IER3 | 5 |
| LUND_SILENCED_BY_METHYLATION | LUND_SILENCED_BY_METHYLATION | LUND_SILENCED_BY_METHYLATION | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | HES1/CLU/NOTCH1/SDC4/HMOX1 | 5 |
| PID_ERBB_NETWORK_PATHWAY | PID_ERBB_NETWORK_PATHWAY | PID_ERBB_NETWORK_PATHWAY | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | TGFA/EREG/BTC/EGF/HBEGF | 5 |
| REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS | REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS | REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | TGFA/TFAP2A/CGB5/CGB8/TFAP2C | 5 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_GRANULOCYTE_UP | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | IFI16/TM4SF1/F2RL1/CRHBP/JUP | 5 |
| TRAYNOR_RETT_SYNDROM_DN | TRAYNOR_RETT_SYNDROM_DN | TRAYNOR_RETT_SYNDROM_DN | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | ITGA6/SEL1L3/AMIGO2/CRIP1/RUNX1 | 5 |
| WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_DN | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | GBP1/GBP4/GBP5/NLRC5/CYSLTR1 | 5 |
| WP_COVID19_ADVERSE_OUTCOME_PATHWAY | WP_COVID19_ADVERSE_OUTCOME_PATHWAY | WP_COVID19_ADVERSE_OUTCOME_PATHWAY | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | AGT/IL1B/CXCL8/IL6/CSF3 | 5 |
| WP_TRANSCRIPTIONAL_ACTIVATION_BY_NRF2_IN_RESPONSE_TO_PHYTOCHEMICALS | WP_TRANSCRIPTIONAL_ACTIVATION_BY_NRF2_IN_RESPONSE_TO_PHYTOCHEMICALS | WP_TRANSCRIPTIONAL_ACTIVATION_BY_NRF2_IN_RESPONSE_TO_PHYTOCHEMICALS | 5/1438 | 15/23056 | 0.3333333 | 5.344460 | 4.340952 | 0.0016605 | 0.0086446 | 0.0055573 | SLC7A11/NQO1/MAF/CEBPB/HMOX1 | 5 |
| HP_ARTERIOVENOUS_MALFORMATION | HP_ARTERIOVENOUS_MALFORMATION | HP_ARTERIOVENOUS_MALFORMATION | 10/1438 | 54/23056 | 0.1851852 | 2.969144 | 3.736336 | 0.0016628 | 0.0086498 | 0.0055607 | COL3A1/COL5A2/ADAMTS3/FAT4/IL6/EPHB4/TEK/COL5A1/NOTCH1/COL1A1 | 10 |
| WP_APOPTOSISRELATED_NETWORK_DUE_TO_ALTERED_NOTCH3_IN_OVARIAN_CANCER | WP_APOPTOSISRELATED_NETWORK_DUE_TO_ALTERED_NOTCH3_IN_OVARIAN_CANCER | WP_APOPTOSISRELATED_NETWORK_DUE_TO_ALTERED_NOTCH3_IN_OVARIAN_CANCER | 10/1438 | 54/23056 | 0.1851852 | 2.969144 | 3.736336 | 0.0016628 | 0.0086498 | 0.0055607 | IL7R/IER3/TNFRSF21/TRAF1/YBX3/THBS1/NQO1/SOCS3/BCL3/APOE | 10 |
| HP_ABNORMALITY_OF_THE_MENSTRUAL_CYCLE | HP_ABNORMALITY_OF_THE_MENSTRUAL_CYCLE | HP_ABNORMALITY_OF_THE_MENSTRUAL_CYCLE | 29/1438 | 259/23056 | 0.1119691 | 1.795243 | 3.319444 | 0.0016682 | 0.0086748 | 0.0055767 | HJV/CCDC141/NABP1/PPARG/FOXL2/PCSK1/HFE/PSMB8/SIM1/SEMA3A/SERPINE1/CAV1/PLAG1/ZFPM2/ITGA8/PLAU/PAPSS2/WT1/VWF/HMGA2/FOS/CYP19A1/BNC1/CAVIN1/SOX9/AXL/BMP2/MYH9/PDGFB | 29 |
| BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | AGRN/IFI44L/IFITM3/OASL/IFI35/MX2/MX1 | 7 |
| BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_UP | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | PRRX1/CD34/TWIST2/HLA-E/PTGR1/ANXA8L1/NQO1 | 7 |
| GENTLES_LEUKEMIC_STEM_CELL_UP | GENTLES_LEUKEMIC_STEM_CELL_UP | GENTLES_LEUKEMIC_STEM_CELL_UP | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | CD34/TMEM200A/VNN1/GIMAP2/RBPMS/BIRC3/ICAM1 | 7 |
| GOBP_MYELOID_DENDRITIC_CELL_ACTIVATION | GOBP_MYELOID_DENDRITIC_CELL_ACTIVATION | GOBP_MYELOID_DENDRITIC_CELL_ACTIVATION | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | ITGB6/TGFBR2/CSF2/DOCK2/ITGB8/TSPAN32/RELB | 7 |
| GOBP_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | GOBP_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | GOBP_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | PLA2G4A/IL1R1/IL1B/ANXA1/IL4R/IL27RA/IL12RB1 | 7 |
| REACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION | REACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION | REACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | WWTR1/LAMA2/ADGRG6/UTRN/YAP1/MBP/MAG | 7 |
| WP_SELECTIVE_EXPRESSION_OF_CHEMOKINE_RECEPTORS_DURING_TCELL_POLARIZATION | WP_SELECTIVE_EXPRESSION_OF_CHEMOKINE_RECEPTORS_DURING_TCELL_POLARIZATION | WP_SELECTIVE_EXPRESSION_OF_CHEMOKINE_RECEPTORS_DURING_TCELL_POLARIZATION | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | TGFB2/CCR3/CSF2/IL4R/CCR7/IL12RB1/TGFB1 | 7 |
| XIE_LT_HSC_S1PR3_OE_UP | XIE_LT_HSC_S1PR3_OE_UP | XIE_LT_HSC_S1PR3_OE_UP | 7/1438 | 29/23056 | 0.2413793 | 3.870126 | 3.988738 | 0.0016747 | 0.0086821 | 0.0055814 | NID1/IL1RAP/LEF1/CD36/MICAL2/ZFP36L1/TGM2 | 7 |
| HP_ABNORMALITY_OF_NEUTROPHILS | HP_ABNORMALITY_OF_NEUTROPHILS | HP_ABNORMALITY_OF_NEUTROPHILS | 30/1438 | 271/23056 | 0.1107011 | 1.774913 | 3.309537 | 0.0016754 | 0.0086824 | 0.0055816 | NEXN/GFI1/FMO3/NLRP3/NABP1/CASP10/DES/TNNC1/TLR3/IL7R/DSP/CAP2/LAMA4/STX11/SAMD9/SAMD9L/MYPN/VCL/FAS/ANKRD1/BAG3/CRYAB/ACTC1/TPM1/DSG2/ELANE/RUNX1/MYH9/RAC2/MSN | 30 |
| MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | 22/1438 | 178/23056 | 0.1235955 | 1.981654 | 3.390889 | 0.0016867 | 0.0087379 | 0.0056173 | S100A10/PTPN14/LYPD1/SERPINE2/BHLHE40/FOXL2/LPP/P3H2/ARAP2/FST/PLK2/TPD52L1/PERP/CTHRC1/ITGA8/ADM/BHLHE41/FOXB1/MT1X/PIEZO1/KRT19/SLC16A3 | 22 |
| GOBP_VIRAL_GENOME_REPLICATION | GOBP_VIRAL_GENOME_REPLICATION | GOBP_VIRAL_GENOME_REPLICATION | 18/1438 | 134/23056 | 0.1343284 | 2.153738 | 3.454518 | 0.0016967 | 0.0087828 | 0.0056461 | ZC3H12A/IFI16/RNASEL/NR5A2/CXCL8/TRIM38/PARP10/NOTCH1/IFITM2/IFITM3/HMGA2/OASL/CCL5/CLEC4M/MX1/APOBEC3A/APOBEC3G/APOBEC3H | 18 |
| HP_ABNORMAL_THROMBOSIS | HP_ABNORMAL_THROMBOSIS | HP_ABNORMAL_THROMBOSIS | 18/1438 | 134/23056 | 0.1343284 | 2.153738 | 3.454518 | 0.0016967 | 0.0087828 | 0.0056461 | PTPN22/CFH/TGFB2/NABP1/CFI/RHAG/CITED2/MET/FLNC/PLAT/NOTCH1/MYPN/FAS/SAA1/PIEZO1/KCNN4/THBD/MYH9 | 18 |
| GOBP_CARDIAC_ATRIUM_DEVELOPMENT | GOBP_CARDIAC_ATRIUM_DEVELOPMENT | GOBP_CARDIAC_ATRIUM_DEVELOPMENT | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | CCN1/TGFB2/BMP10/WNT5A/HEG1/NOTCH1/NOG/BMP2 | 8 |
| GOBP_CARDIAC_CONDUCTION_SYSTEM_DEVELOPMENT | GOBP_CARDIAC_CONDUCTION_SYSTEM_DEVELOPMENT | GOBP_CARDIAC_CONDUCTION_SYSTEM_DEVELOPMENT | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | TBX18/GJA1/MSC/NOTCH1/BMP4/HCN4/GATA6/DSG2 | 8 |
| GOBP_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | GOBP_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | TGFB2/TGFBR2/HAS2/NOTCH1/BMP4/NOG/TGFB1/BMP2 | 8 |
| HP_ABNORMAL_BLOOD_GAS_LEVEL | HP_ABNORMAL_BLOOD_GAS_LEVEL | HP_ABNORMAL_BLOOD_GAS_LEVEL | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | FGFR3/SLC34A2/RHAG/ZFPM2/TPM2/ITGA7/FBN1/GATA6 | 8 |
| MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS | MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS | MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | GYPC/P3H2/FGFR3/GALNT10/KLF4/YBX3/NUAK1/MAF | 8 |
| SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS | SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS | SNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | TM4SF1/IL7R/PTP4A1/FZD1/ADAM9/CD44/YAP1/BIRC3 | 8 |
| STEARMAN_TUMOR_FIELD_EFFECT_UP | STEARMAN_TUMOR_FIELD_EFFECT_UP | STEARMAN_TUMOR_FIELD_EFFECT_UP | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | CTSS/SPP1/PTGS1/SERPINA10/CD68/SOCS3/SIRPA/SAT1 | 8 |
| WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN | WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN | WANG_BARRETTS_ESOPHAGUS_AND_ESOPHAGUS_CANCER_DN | 8/1438 | 37/23056 | 0.2162162 | 3.466677 | 3.872791 | 0.0017054 | 0.0088016 | 0.0056582 | CDA/ECM1/S100A2/CRABP2/ANXA1/ANXA8/EMP1/KRT4 | 8 |
| GOCC_TRANSCRIPTION_REGULATOR_COMPLEX | GOCC_TRANSCRIPTION_REGULATOR_COMPLEX | GOCC_TRANSCRIPTION_REGULATOR_COMPLEX | 47/1438 | 483/23056 | 0.0973085 | 1.560184 | 3.208957 | 0.0017123 | 0.0088337 | 0.0056789 | RUNX3/GFI1/TBX15/NR5A2/NPAS2/PPARG/THRB/WWTR1/LEF1/RUNX2/GCM1/TBX18/AHR/GLI3/CEBPD/KLF4/ANKRD1/TCF7L2/ALX4/FOSL1/YAP1/BCL9L/NFE2/STAT6/AJUBA/IRF9/NFATC4/SIX1/SIX4/FOS/SMAD6/SOX8/MAF/FOXF1/LHX1/HOXB13/SOX9/GATA6/ELANE/WTIP/RELB/SIX5/ZNF541/CEBPB/NFATC2/RUNX1/DACH2 | 47 |
| GOMF_UDP_GLYCOSYLTRANSFERASE_ACTIVITY | GOMF_UDP_GLYCOSYLTRANSFERASE_ACTIVITY | GOMF_UDP_GLYCOSYLTRANSFERASE_ACTIVITY | 19/1438 | 145/23056 | 0.1310345 | 2.100926 | 3.429843 | 0.0017211 | 0.0088722 | 0.0057036 | GALNT5/GALNT3/GALNT15/GXYLT2/UGT2B7/GALNTL6/CHSY3/GALNT10/B3GALT4/GALNT17/CSGALNACT1/EXT1/HAS2/B4GALT1/GALNT18/GALNT9/B3GNT3/HAS1/A4GALT | 19 |
| HP_TELECANTHUS | HP_TELECANTHUS | HP_TELECANTHUS | 19/1438 | 145/23056 | 0.1310345 | 2.100926 | 3.429843 | 0.0017211 | 0.0088722 | 0.0057036 | PTCH2/KCNN3/COL3A1/TWIST2/MITF/FOXL2/FGFR3/FOXC1/RREB1/TFAP2A/GJA1/GLI3/COLEC10/FGFR2/ALX4/EDNRB/FBN1/ADAMTS18/MID1 | 19 |
| HP_GASTROINTESTINAL_INFLAMMATION | HP_GASTROINTESTINAL_INFLAMMATION | HP_GASTROINTESTINAL_INFLAMMATION | 16/1438 | 113/23056 | 0.1415929 | 2.270213 | 3.490960 | 0.0017273 | 0.0089012 | 0.0057223 | LAMC2/LAMB3/TGFB2/CASP10/TGFBR2/COL7A1/ADAMTS2/TNFAIP3/STX11/IL6/TNFSF15/FAS/MMP1/ELANE/IL12RB1/TGFB1 | 16 |
| GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_LYMPHOCYTE_MEDIATED_IMMUNITY | 37/1438 | 357/23056 | 0.1036415 | 1.661723 | 3.249833 | 0.0017341 | 0.0089327 | 0.0057426 | TNFRSF1B/MR1/PTPRC/NLRP3/IL1R1/IL1B/CD96/BCL6/CFI/IL7R/C9/HFE/HLA-E/MICA/RAET1E/AHR/IL6/CLU/MBL2/C1S/C1R/C1RL/KLRD1/KLRC4-KLRK1/NCKAP1L/STAT6/IL4R/IL21R/CD70/C3/ICAM1/IL27RA/IL12RB1/TGFB1/BCL3/NECTIN2/IL4I1 | 37 |
| HP_ABNORMAL_NEPHRON_MORPHOLOGY | HP_ABNORMAL_NEPHRON_MORPHOLOGY | HP_ABNORMAL_NEPHRON_MORPHOLOGY | 28/1438 | 248/23056 | 0.1129032 | 1.810220 | 3.308565 | 0.0017557 | 0.0090404 | 0.0058118 | PTPN22/FCGR2A/LAMC2/CFH/LAMB3/AGT/CASP10/FN1/COL7A1/LAMB2/MME/ARHGAP24/CFI/TMEM270/CRB2/FAS/WT1/MMP1/SLC7A7/MYO1E/MYOCD/ITGA3/ITGB4/C3/APOE/APOL1/TBC1D8B/COL4A5 | 28 |
| GOBP_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 12/1438 | 73/23056 | 0.1643836 | 2.635624 | 3.609905 | 0.0017605 | 0.0090552 | 0.0058213 | IFI16/NMI/PPARG/CD96/PARP14/HLA-E/MICA/TNFAIP3/KLRD1/NLRC5/DHX58/USP18 | 12 |
| GOBP_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION | 12/1438 | 73/23056 | 0.1643836 | 2.635624 | 3.609905 | 0.0017605 | 0.0090552 | 0.0058213 | PPARG/IL15/NPR3/TNFAIP3/SOD2/EFEMP2/TPM1/MYOCD/CNN1/APOE/BMP2/HMOX1 | 12 |
| GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION | 12/1438 | 73/23056 | 0.1643836 | 2.635624 | 3.609905 | 0.0017605 | 0.0090552 | 0.0058213 | GBP5/S100A13/IFI16/NLRP3/CASP8/WNT5A/F2RL1/IL6/CD36/GSDMD/SAA1/CASP1 | 12 |
| GOBP_REGULATION_OF_INTRACELLULAR_TRANSPORT | GOBP_REGULATION_OF_INTRACELLULAR_TRANSPORT | GOBP_REGULATION_OF_INTRACELLULAR_TRANSPORT | 35/1438 | 333/23056 | 0.1051051 | 1.685190 | 3.248288 | 0.0017963 | 0.0092360 | 0.0059375 | LDLRAP1/ZC3H12A/PTGS2/PTPN14/IL1B/SP100/TNNC1/DAB2/SH3TC2/ABLIM3/MICALL2/GLI3/CD36/MDFIC/TCAF2/SHH/ANGPT1/GAS1/TCF7L2/BAG3/CRYAB/LCP1/PRKD1/BMP4/ANXA2/HAP1/JUP/TGFB1/EHD2/PRNP/MX2/RAC2/MLC1/MSN/TENM1 | 35 |
| HP_RENAL_HYPOPLASIA | HP_RENAL_HYPOPLASIA | HP_RENAL_HYPOPLASIA | 17/1438 | 124/23056 | 0.1370968 | 2.198125 | 3.450215 | 0.0018016 | 0.0092595 | 0.0059526 | KYNU/RARB/FGFR3/FAT4/RREB1/TBX18/GLI3/TMEM270/FGFR2/HMGA2/GRIP1/FREM2/BMP4/DACT1/SALL1/KCNJ2/PIEZO2 | 17 |
| CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | 22/1438 | 179/23056 | 0.1229050 | 1.970583 | 3.362125 | 0.0018125 | 0.0093089 | 0.0059844 | HJV/FMO3/HSD11B1/AOX1/RTP3/ALDH1L1/AADAC/LECT2/ADRB2/SLC22A1/PDK4/CPED1/SLC38A4/OASL/HPD/SLC46A3/SERPINA10/LDHD/ABCA8/ABCA6/CYP4F11/COL18A1 | 22 |
| HP_ABNORMAL_ATRIOVENTRICULAR_VALVE_PHYSIOLOGY | HP_ABNORMAL_ATRIOVENTRICULAR_VALVE_PHYSIOLOGY | HP_ABNORMAL_ATRIOVENTRICULAR_VALVE_PHYSIOLOGY | 22/1438 | 179/23056 | 0.1229050 | 1.970583 | 3.362125 | 0.0018125 | 0.0093089 | 0.0059844 | LDLRAP1/COL5A2/PLD1/GJA1/CITED2/TMEM270/FLNC/CSGALNACT1/COL5A1/NOTCH1/MYPN/FAS/CRYAB/LTBP2/FBLN5/ACTC1/FBN1/TPM1/ALPK3/COL1A1/GATA6/BGN | 22 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_BINDING | GOBP_POSITIVE_REGULATION_OF_PROTEIN_BINDING | GOBP_POSITIVE_REGULATION_OF_PROTEIN_BINDING | 13/1438 | 83/23056 | 0.1566265 | 2.511252 | 3.557307 | 0.0018167 | 0.0093270 | 0.0059960 | WNT5A/STING1/HFE/CAV1/CTHRC1/NRP1/TCF7L2/BMP4/DACT1/ANXA2/CSF3/APOE/BMP2 | 13 |
| BIOCARTA_CASPASE_PATHWAY | BIOCARTA_CASPASE_PATHWAY | BIOCARTA_CASPASE_PATHWAY | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | CASP10/CASP8/BIRC3/CASP4/CASP1/ARHGDIB | 6 |
| GOBP_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | EREG/PRDM6/SHH/RBPMS2/NFATC2/PDGFB | 6 |
| GOBP_NEGATIVE_REGULATION_OF_TISSUE_REMODELING | GOBP_NEGATIVE_REGULATION_OF_TISSUE_REMODELING | GOBP_NEGATIVE_REGULATION_OF_TISSUE_REMODELING | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | AGT/PPARG/TNFAIP3/IL6/TNFRSF11B/UBASH3B | 6 |
| GOBP_PYROPTOSIS | GOBP_PYROPTOSIS | GOBP_PYROPTOSIS | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | CASP8/GSDMD/NLRP6/CASP4/CASP1/ELANE | 6 |
| GOBP_STEROID_HORMONE_SECRETION | GOBP_STEROID_HORMONE_SECRETION | GOBP_STEROID_HORMONE_SECRETION | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | AGT/DAB2/BMP6/INHBA/FZD4/C1QTNF1 | 6 |
| GOBP_THYMIC_T_CELL_SELECTION | GOBP_THYMIC_T_CELL_SELECTION | GOBP_THYMIC_T_CELL_SELECTION | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | PTPRC/ITPKB/DOCK2/GLI3/SHH/CCR7 | 6 |
| HP_GENERALIZED_EDEMA | HP_GENERALIZED_EDEMA | HP_GENERALIZED_EDEMA | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | CFH/MYLK/DOK7/CFI/PIEZO1/PLVAP | 6 |
| HP_STRIAE_DISTENSAE | HP_STRIAE_DISTENSAE | HP_STRIAE_DISTENSAE | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | TGFB2/COL5A2/TGFBR2/COL5A1/FBN1/COL1A1 | 6 |
| LU_TUMOR_ENDOTHELIAL_MARKERS_UP | LU_TUMOR_ENDOTHELIAL_MARKERS_UP | LU_TUMOR_ENDOTHELIAL_MARKERS_UP | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | TNFRSF21/STC1/PAMR1/POSTN/ADAP2/MXRA5 | 6 |
| MATZUK_IMPLANTATION_AND_UTERINE | MATZUK_IMPLANTATION_AND_UTERINE | MATZUK_IMPLANTATION_AND_UTERINE | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | CSF1/PTGS2/HMX3/PGR/LHX1/NDP | 6 |
| MURATA_VIRULENCE_OF_H_PILORI | MURATA_VIRULENCE_OF_H_PILORI | MURATA_VIRULENCE_OF_H_PILORI | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | DPP4/BCL6/SOD2/MMP1/IL11/COL6A2 | 6 |
| REACTOME_RA_BIOSYNTHESIS_PATHWAY | REACTOME_RA_BIOSYNTHESIS_PATHWAY | REACTOME_RA_BIOSYNTHESIS_PATHWAY | 6/1438 | 22/23056 | 0.2727273 | 4.372740 | 4.081913 | 0.0018267 | 0.0093362 | 0.0060019 | DHRS3/CYP26B1/AKR1C3/CYP26A1/ALDH1A2/ALDH1A3 | 6 |
| GOBP_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 24/1438 | 202/23056 | 0.1188119 | 1.904956 | 3.331780 | 0.0018365 | 0.0093825 | 0.0060317 | ZC3H12A/TNFSF18/PTPRC/NLRP3/BCL6/LEF1/F2RL1/IL6/ST3GAL1/IFNE/ANXA1/APBB1IP/NCKAP1L/STAT6/LCP1/IL4R/ICAM1/IL27RA/IL12RB1/TGFB1/BCL3/RELB/LGALS1/ITM2A | 24 |
| GOBP_NEGATIVE_REGULATION_OF_AXONOGENESIS | GOBP_NEGATIVE_REGULATION_OF_AXONOGENESIS | GOBP_NEGATIVE_REGULATION_OF_AXONOGENESIS | 11/1438 | 64/23056 | 0.1718750 | 2.755737 | 3.627566 | 0.0018682 | 0.0095339 | 0.0061290 | SEMA3B/WNT5A/SPP1/SEMA5A/SEMA3C/SEMA3A/SEMA3D/NRP1/MBP/SEMA6B/MAG | 11 |
| LEE_LIVER_CANCER_E2F1_DN | LEE_LIVER_CANCER_E2F1_DN | LEE_LIVER_CANCER_E2F1_DN | 11/1438 | 64/23056 | 0.1718750 | 2.755737 | 3.627566 | 0.0018682 | 0.0095339 | 0.0061290 | CFH/HSD11B1/KYNU/IL1RAP/ABCG2/TDO2/LECT2/GPR37/IGF1/HPD/ELANE | 11 |
| PID_IL4_2PATHWAY | PID_IL4_2PATHWAY | PID_IL4_2PATHWAY | 11/1438 | 64/23056 | 0.1718750 | 2.755737 | 3.627566 | 0.0018682 | 0.0095339 | 0.0061290 | PARP14/BCL6/CCL26/DOK2/MYBL1/STAT6/IL4R/COL1A1/SOCS3/CEBPB/IL13RA1 | 11 |
| GOBP_BLOOD_VESSEL_REMODELING | GOBP_BLOOD_VESSEL_REMODELING | GOBP_BLOOD_VESSEL_REMODELING | 9/1438 | 46/23056 | 0.1956522 | 3.136966 | 3.741729 | 0.0018820 | 0.0095833 | 0.0061608 | AGT/FOXC1/RSPO3/HOXA3/SEMA3C/EXT1/AXL/TGFB1/LIF | 9 |
| GOBP_ENDOCRINE_PANCREAS_DEVELOPMENT | GOBP_ENDOCRINE_PANCREAS_DEVELOPMENT | GOBP_ENDOCRINE_PANCREAS_DEVELOPMENT | 9/1438 | 46/23056 | 0.1956522 | 3.136966 | 3.741729 | 0.0018820 | 0.0095833 | 0.0061608 | WNT5A/HES1/BMP6/IL6/ANXA1/BMP4/GIP/SOX9/GATA6 | 9 |
| GOBP_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION | 9/1438 | 46/23056 | 0.1956522 | 3.136966 | 3.741729 | 0.0018820 | 0.0095833 | 0.0061608 | RUNX3/ZC3H12A/BCL6/GLI3/SHH/ANXA1/BMP4/IL4R/RUNX1 | 9 |
| HP_ATRESIA_OF_THE_EXTERNAL_AUDITORY_CANAL | HP_ATRESIA_OF_THE_EXTERNAL_AUDITORY_CANAL | HP_ATRESIA_OF_THE_EXTERNAL_AUDITORY_CANAL | 9/1438 | 46/23056 | 0.1956522 | 3.136966 | 3.741729 | 0.0018820 | 0.0095833 | 0.0061608 | TWIST2/FAT4/HOXA2/GLI3/FGFR2/GRIP1/FREM2/SIX1/SIX5 | 9 |
| HP_UVEITIS | HP_UVEITIS | HP_UVEITIS | 9/1438 | 46/23056 | 0.1956522 | 3.136966 | 3.741729 | 0.0018820 | 0.0095833 | 0.0061608 | PTPN22/NLRP3/CASP10/TNFAIP3/IL6/FAS/BIRC3/TNFRSF1A/IL2RB | 9 |
| JIANG_TIP30_TARGETS_UP | JIANG_TIP30_TARGETS_UP | JIANG_TIP30_TARGETS_UP | 9/1438 | 46/23056 | 0.1956522 | 3.136966 | 3.741729 | 0.0018820 | 0.0095833 | 0.0061608 | CCN1/HNMT/ITGA6/BCL6/IER3/IFITM2/MMP3/ANXA2/AXL | 9 |
| HP_NEOPLASM_OF_THE_SKIN | HP_NEOPLASM_OF_THE_SKIN | HP_NEOPLASM_OF_THE_SKIN | 23/1438 | 191/23056 | 0.1204188 | 1.930721 | 3.331232 | 0.0018955 | 0.0096450 | 0.0062004 | TNFRSF4/TNFRSF1B/PTCH2/ECM1/LAMC2/LAMB3/CASP10/TGFBR2/COL7A1/MITF/SLCO2A1/VEGFC/GJA1/PERP/SASH1/IL6/COL14A1/FAS/MMP1/KRT17/COL1A1/TMC8/PDGFB | 23 |
| WP_GASTRIN_SIGNALING_PATHWAY | WP_GASTRIN_SIGNALING_PATHWAY | WP_GASTRIN_SIGNALING_PATHWAY | 16/1438 | 114/23056 | 0.1403509 | 2.250299 | 3.451476 | 0.0018956 | 0.0096450 | 0.0062004 | PTGS2/PPARG/CLDN1/CXCL8/SERPINE1/KLF4/CCKBR/CD44/BIRC3/FOXO1/PRKD1/NFKBIA/FOS/ANXA2/SERPINB2/BMP2 | 16 |
| GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION | 10/1438 | 55/23056 | 0.1818182 | 2.915160 | 3.667476 | 0.0019207 | 0.0097618 | 0.0062756 | RUNX3/ZC3H12A/BCL6/INHBA/GLI3/SHH/ANXA1/BMP4/IL4R/RUNX1 | 10 |
| GOBP_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 10/1438 | 55/23056 | 0.1818182 | 2.915160 | 3.667476 | 0.0019207 | 0.0097618 | 0.0062756 | PDGFC/PDGFA/PDGFRL/PLAT/NRP1/PTPRJ/MYO1E/CSPG4/MYOCD/PDGFB | 10 |
| GOBP_REGULATION_OF_LIPID_STORAGE | GOBP_REGULATION_OF_LIPID_STORAGE | GOBP_REGULATION_OF_LIPID_STORAGE | 10/1438 | 55/23056 | 0.1818182 | 2.915160 | 3.667476 | 0.0019207 | 0.0097618 | 0.0062756 | ZC3H12A/IKBKE/PPARG/IL6/CD36/MEST/MSR1/NFKBIA/CES1/C3 | 10 |
| GOBP_REGULATION_OF_CELL_SIZE | GOBP_REGULATION_OF_CELL_SIZE | GOBP_REGULATION_OF_CELL_SIZE | 22/1438 | 180/23056 | 0.1222222 | 1.959635 | 3.333548 | 0.0019463 | 0.0098884 | 0.0063569 | CRABP2/SCTR/FN1/SEMA3B/WNT5A/SLC12A8/SPP1/SLC12A7/SEMA5A/IL7R/EDN1/AQP1/SEMA3C/SEMA3A/SEMA3D/NRP1/TRPV2/SEMA6B/MAG/KCNN4/APOE/MSN | 22 |
| ZWANG_EGF_INTERVAL_DN | ZWANG_EGF_INTERVAL_DN | ZWANG_EGF_INTERVAL_DN | 27/1438 | 238/23056 | 0.1134454 | 1.818913 | 3.275229 | 0.0019588 | 0.0099485 | 0.0063955 | SPSB1/ZC3H12A/ELF3/WNT9A/OSR1/ARL14/PLD1/HES1/ARHGAP24/HFE/TPD52L1/HOXA1/SERPINE1/MATN2/DKK1/PLAU/EHF/PLAAT4/BMP4/AHNAK2/CLDN7/GRB7/LLGL2/MBP/ZFP36/CEBPB/TFAP2C | 27 |
| HP_ABNORMALITY_OF_CIRCULATING_ENZYME_LEVEL | HP_ABNORMALITY_OF_CIRCULATING_ENZYME_LEVEL | HP_ABNORMALITY_OF_CIRCULATING_ENZYME_LEVEL | 32/1438 | 298/23056 | 0.1073826 | 1.721705 | 3.234113 | 0.0019634 | 0.0099683 | 0.0064082 | HSPG2/NEXN/CASQ1/DES/COL6A3/TNNC1/DOK7/DSP/CAP2/COL12A1/LAMA4/LAMA2/TMEM270/FLNC/B4GALT1/TPM2/MYPN/VCL/ANKRD1/BAG3/PYGM/CRYAB/ITGA7/ACTC1/TPM1/CAVIN1/SGCA/ITGB4/PIEZO2/DSG2/COL9A3/COL6A2 | 32 |
| CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | 17/1438 | 125/23056 | 0.1360000 | 2.180540 | 3.413330 | 0.0019667 | 0.0099813 | 0.0064166 | PDZK1IP1/ELF3/ITGB6/CDS1/RNF144B/CRYBG1/MACC1/AKR1B10/GSN/PRRG4/EHF/SCNN1A/GRAMD2A/MAF/KRT15/ZFP36/KLK6 | 17 |
| HP_ABNORMAL_BLISTERING_OF_THE_SKIN | HP_ABNORMAL_BLISTERING_OF_THE_SKIN | HP_ABNORMAL_BLISTERING_OF_THE_SKIN | 15/1438 | 104/23056 | 0.1442308 | 2.312507 | 3.459889 | 0.0019714 | 0.0099978 | 0.0064272 | MMP23B/HSPG2/ECM1/LAMC2/LAMB3/ITGA6/COL7A1/DSP/GJA1/FAS/MMP1/KRT17/ITGA3/ITGB4/RUNX1 | 15 |
| HP_SEPSIS | HP_SEPSIS | HP_SEPSIS | 15/1438 | 104/23056 | 0.1442308 | 2.312507 | 3.459889 | 0.0019714 | 0.0099978 | 0.0064272 | ECE1/LAMC2/LMOD1/LAMB3/ACTG2/MYLK/IL7R/GDNF/SEMA3C/SEMA3D/SAMD9/NFKB2/EDNRB/ELANE/RAC2 | 15 |
| GOBP_EMBRYONIC_PATTERN_SPECIFICATION | GOBP_EMBRYONIC_PATTERN_SPECIFICATION | GOBP_EMBRYONIC_PATTERN_SPECIFICATION | 12/1438 | 74/23056 | 0.1621622 | 2.600007 | 3.555480 | 0.0019843 | 0.0100555 | 0.0064644 | NRP2/WNT5A/TDRD6/SEMA3A/SHH/NRP1/FGFR2/WT1/SMAD6/LHX1/MEOX1/SIM2 | 12 |
| HP_ECTOPIC_ANUS | HP_ECTOPIC_ANUS | HP_ECTOPIC_ANUS | 12/1438 | 74/23056 | 0.1621622 | 2.600007 | 3.555480 | 0.0019843 | 0.0100555 | 0.0064644 | FAT4/GLI3/SHH/GDF6/GAS1/FGFR2/GRIP1/FREM2/ZIC2/DACT1/SALL1/MEOX1 | 12 |
| GOCC_ANCHORED_COMPONENT_OF_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_MEMBRANE | GOCC_ANCHORED_COMPONENT_OF_MEMBRANE | 21/1438 | 169/23056 | 0.1242604 | 1.992314 | 3.339274 | 0.0019861 | 0.0100573 | 0.0064655 | HJV/LYPD1/LYPD6B/TFPI/MDGA1/CD109/NT5E/VNN1/VNN2/TNFRSF10C/LY6K/GAS1/TECTB/OPCML/CPM/MSLN/CDH13/LYPD3/PRNP/PRND/GPC4 | 21 |
| HP_CARIOUS_TEETH | HP_CARIOUS_TEETH | HP_CARIOUS_TEETH | 21/1438 | 169/23056 | 0.1242604 | 1.992314 | 3.339274 | 0.0019861 | 0.0100573 | 0.0064655 | PTCH2/LAMC2/LAMB3/COL3A1/COL7A1/FGFR3/SGMS2/RREB1/RUNX2/TENT5A/GJA1/CCN2/PERP/TMEM270/CAV1/TRPS1/FGFR2/MMP1/SLC24A4/ITGB4/TGFB1 | 21 |
| GOBP_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | GOBP_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | GOBP_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | 25/1438 | 215/23056 | 0.1162791 | 1.864346 | 3.284005 | 0.0020150 | 0.0101997 | 0.0065570 | EDN2/CRABP2/PTGS2/PLA2G4A/IL1B/MGLL/TECRL/EDN1/CYP39A1/PDK4/IDO1/ANXA1/PTGS1/AKR1C3/ALOX5/APOC3/APOA1/CYP46A1/ALDH1A2/ALDH1A3/ACSM3/CES1/GIP/LIPG/PTGIS | 25 |
| GOBP_ORGANIC_ACID_TRANSPORT | GOBP_ORGANIC_ACID_TRANSPORT | GOBP_ORGANIC_ACID_TRANSPORT | 34/1438 | 323/23056 | 0.1052632 | 1.687724 | 3.210269 | 0.0020194 | 0.0102182 | 0.0065689 | SLC1A7/CRABP2/PLA2G4A/AGT/IL1A/IL1B/PPARG/ABCG2/SLC7A11/SLC6A7/EDN1/GJA1/CD36/SLC26A4/FABP4/SLC26A7/ANXA1/ACSL5/SLC5A12/SLCO2B1/SLC6A13/SPX/SLC38A4/TRPC4/SLC10A2/SLC7A7/THBS1/SLC47A1/ABCC3/LLGL2/SLC16A3/TNFRSF11A/SLC7A10/APOE | 34 |
| GOBP_EMBRYONIC_HEART_TUBE_DEVELOPMENT | GOBP_EMBRYONIC_HEART_TUBE_DEVELOPMENT | GOBP_EMBRYONIC_HEART_TUBE_DEVELOPMENT | 13/1438 | 84/23056 | 0.1547619 | 2.481356 | 3.507955 | 0.0020292 | 0.0102545 | 0.0065923 | ECE1/PIFO/TGFBR2/WNT5A/HES1/FOXC1/EDN1/GJA1/CITED2/SHH/NOTCH1/MICAL2/YAP1 | 13 |
| HP_HEPATITIS | HP_HEPATITIS | HP_HEPATITIS | 13/1438 | 84/23056 | 0.1547619 | 2.481356 | 3.507955 | 0.0020292 | 0.0102545 | 0.0065923 | CASP10/CASP8/IL17RC/MET/PDGFRL/GLIS3/TNFSF15/FAS/C1S/SERPINA1/IL21R/PIEZO1/IL12RB1 | 13 |
| WP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE | WP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE | WP_EGFR_TYROSINE_KINASE_INHIBITOR_RESISTANCE | 13/1438 | 84/23056 | 0.1547619 | 2.481356 | 3.507955 | 0.0020292 | 0.0102545 | 0.0065923 | TGFA/FGFR3/KDR/EGF/PDGFC/PDGFA/IL6/MET/FGFR2/IGF1/AXL/RRAS/PDGFB | 13 |
| GOBP_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_REGULATION_OF_NEURON_DIFFERENTIATION | 23/1438 | 192/23056 | 0.1197917 | 1.920665 | 3.303928 | 0.0020295 | 0.0102545 | 0.0065923 | BRINP3/DLX1/DLX2/BCL6/HES1/BMP6/ID4/HOXA2/GLI3/SHH/FGF20/GDF6/NOTCH1/DKK1/EDNRB/BMP4/SIX1/LTK/SOX8/SOX9/S1PR5/MAG/BMP2 | 23 |
| BURTON_ADIPOGENESIS_PEAK_AT_8HR | BURTON_ADIPOGENESIS_PEAK_AT_8HR | BURTON_ADIPOGENESIS_PEAK_AT_8HR | 8/1438 | 38/23056 | 0.2105263 | 3.375448 | 3.779704 | 0.0020438 | 0.0103002 | 0.0066217 | IFI16/EREG/PLAC8/CD44/FOSL1/ITGA5/HMGA2/CEBPB | 8 |
| GOBP_FORELIMB_MORPHOGENESIS | GOBP_FORELIMB_MORPHOGENESIS | GOBP_FORELIMB_MORPHOGENESIS | 8/1438 | 38/23056 | 0.2105263 | 3.375448 | 3.779704 | 0.0020438 | 0.0103002 | 0.0066217 | CRABP2/OSR1/TFAP2A/RUNX2/SHH/RSPO2/ALX4/ALDH1A2 | 8 |
| GOBP_POSITIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY | 8/1438 | 38/23056 | 0.2105263 | 3.375448 | 3.779704 | 0.0020438 | 0.0103002 | 0.0066217 | AGT/TGFA/EPGN/EREG/BTC/EGF/HBEGF/HAP1 | 8 |
| GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_HORMONE | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_HORMONE | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_HORMONE | 8/1438 | 38/23056 | 0.2105263 | 3.375448 | 3.779704 | 0.0020438 | 0.0103002 | 0.0066217 | ECE1/EDN2/AGT/SUCNR1/F2RL1/EDN1/PCSK5/EDNRB | 8 |
| GOBP_SKELETAL_MUSCLE_TISSUE_REGENERATION | GOBP_SKELETAL_MUSCLE_TISSUE_REGENERATION | GOBP_SKELETAL_MUSCLE_TISSUE_REGENERATION | 8/1438 | 38/23056 | 0.2105263 | 3.375448 | 3.779704 | 0.0020438 | 0.0103002 | 0.0066217 | TGFBR2/GJA1/SPAAR/ANXA1/MYOZ1/WNT10B/IGF1/SGCA | 8 |
| GOMF_FRIZZLED_BINDING | GOMF_FRIZZLED_BINDING | GOMF_FRIZZLED_BINDING | 8/1438 | 38/23056 | 0.2105263 | 3.375448 | 3.779704 | 0.0020438 | 0.0103002 | 0.0066217 | WNT9A/WNT5A/RSPO3/FZD1/CTHRC1/WNT10B/WNT7B/NDP | 8 |
| VALK_AML_CLUSTER_11 | VALK_AML_CLUSTER_11 | VALK_AML_CLUSTER_11 | 8/1438 | 38/23056 | 0.2105263 | 3.375448 | 3.779704 | 0.0020438 | 0.0103002 | 0.0066217 | CD34/KYNU/ITGA6/DAB2/SPARC/MDFIC/KCNN4/GAS2L1 | 8 |
| CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | GFI1/MME/BCL6/CXCL8/EPHB6/NID2/MX1 | 7 |
| DAZARD_UV_RESPONSE_CLUSTER_G2 | DAZARD_UV_RESPONSE_CLUSTER_G2 | DAZARD_UV_RESPONSE_CLUSTER_G2 | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | CXCL8/CXCL3/CXCL2/IER3/CCN2/CITED2/PHLDA2 | 7 |
| GOBP_LYMPH_VESSEL_DEVELOPMENT | GOBP_LYMPH_VESSEL_DEVELOPMENT | GOBP_LYMPH_VESSEL_DEVELOPMENT | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | EPHA2/TIE1/PTPN14/HEG1/KDR/VEGFC/FOXC1 | 7 |
| GOBP_NEURON_PROJECTION_ARBORIZATION | GOBP_NEURON_PROJECTION_ARBORIZATION | GOBP_NEURON_PROJECTION_ARBORIZATION | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | WNT5A/TPBG/SEMA3A/PTN/NRP1/FZD4/GRIP1 | 7 |
| GOBP_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | BMP10/ZFPM2/NOTCH1/FGFR2/YAP1/GLI1/GATA6 | 7 |
| HP_CONICAL_INCISOR | HP_CONICAL_INCISOR | HP_CONICAL_INCISOR | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | TGFA/FGFR3/FGFR2/WNT10B/GLI1/BMP4/DLX4 | 7 |
| HP_SYNOSTOSIS_INVOLVING_BONES_OF_THE_LOWER_LIMBS | HP_SYNOSTOSIS_INVOLVING_BONES_OF_THE_LOWER_LIMBS | HP_SYNOSTOSIS_INVOLVING_BONES_OF_THE_LOWER_LIMBS | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | FGFR3/GLI3/GDF6/TPM2/FGFR2/SALL1/NOG | 7 |
| MARSON_FOXP3_TARGETS_STIMULATED_UP | MARSON_FOXP3_TARGETS_STIMULATED_UP | MARSON_FOXP3_TARGETS_STIMULATED_UP | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | PTPN22/ANXA1/TNFRSF19/ZFP36L1/CDYL2/MBP/TNFSF14 | 7 |
| SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP | SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP | SARTIPY_NORMAL_AT_INSULIN_RESISTANCE_UP | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | SPSB1/BHLHE40/EREG/SYNJ2/FOSL1/PHLDA1/HMOX1 | 7 |
| SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN | SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN | SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | ATP2B4/BHLHE40/TRAF1/NFKB2/HBD/RELB/PLS3 | 7 |
| SU_PLACENTA | SU_PLACENTA | SU_PLACENTA | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | GCM1/PHLDA2/FLT1/CYP19A1/HOXB3/SERPINB2/MAGEA10 | 7 |
| SUMI_HNF4A_TARGETS | SUMI_HNF4A_TARGETS | SUMI_HNF4A_TARGETS | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | IL22RA1/SULT1C2/SLCO2B1/SOAT2/CYP19A1/SLC47A1/LGALS2 | 7 |
| VALK_AML_CLUSTER_4 | VALK_AML_CLUSTER_4 | VALK_AML_CLUSTER_4 | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | ITGA4/FZD6/YBX3/DRAM1/LRP10/IL4R/KLF2 | 7 |
| WP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS | WP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS | WP_EXTRACELLULAR_VESICLEMEDIATED_SIGNALING_IN_RECIPIENT_CELLS | 7/1438 | 30/23056 | 0.2333333 | 3.741122 | 3.874663 | 0.0020683 | 0.0103700 | 0.0066665 | TGFB2/TGFA/TGFBR2/WNT5A/MET/MFGE8/TGFB1 | 7 |
| GOBP_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE | 16/1438 | 115/23056 | 0.1391304 | 2.230731 | 3.412402 | 0.0020773 | 0.0104075 | 0.0066906 | MR1/PLA2G4A/PTPRC/NLRP3/IL1R1/IL1B/HLA-E/IL6/CD274/STAT6/TNFSF13B/C3/IL27RA/IL12RB1/TGFB1/NECTIN2 | 16 |
| HP_ABNORMAL_SCLERA_MORPHOLOGY | HP_ABNORMAL_SCLERA_MORPHOLOGY | HP_ABNORMAL_SCLERA_MORPHOLOGY | 16/1438 | 115/23056 | 0.1391304 | 2.230731 | 3.412402 | 0.0020773 | 0.0104075 | 0.0066906 | NLRP3/COL3A1/TGFBR2/WNT5A/ADAMTS2/PSMB8/COL12A1/TENT5A/COL5A1/CREB3L1/SERPINH1/C1R/DACT1/FBN1/SALL1/COL1A1 | 16 |
| GOMF_CATION_CHANNEL_ACTIVITY | GOMF_CATION_CHANNEL_ACTIVITY | GOMF_CATION_CHANNEL_ACTIVITY | 35/1438 | 336/23056 | 0.1041667 | 1.670144 | 3.191447 | 0.0020885 | 0.0104599 | 0.0067243 | MCOLN2/KCNN3/TMEM63A/TMEM37/KCNE4/TRPM8/TRPC3/ITPR3/AQP1/PKD1L1/TRPA1/TMC1/TRPM6/LRRC55/CATSPER1/CACNA2D4/KCNA5/SCNN1A/KCNH3/TPCN1/TRPC4/SLC24A4/ANXA2/HCN4/ORAI3/PIEZO1/TRPV2/KCNJ2/PIEZO2/CACNA1A/SCN1B/KCNK6/KCNN4/KCNA7/CACNG6 | 35 |
| HP_ABNORMALITY_OF_THE_PHARYNX | HP_ABNORMALITY_OF_THE_PHARYNX | HP_ABNORMALITY_OF_THE_PHARYNX | 24/1438 | 204/23056 | 0.1176471 | 1.886280 | 3.279277 | 0.0020961 | 0.0104941 | 0.0067463 | HSPG2/GFI1/PTPN22/COL5A2/CFI/DNAH5/IL7R/MCIDAS/RREB1/PSMB8/TAPBP/GJA1/GLI3/SHH/COL5A1/NFKB2/FGFR2/TNFRSF1A/SCNN1A/IL21R/SOX9/ELANE/RAC2/MID1 | 24 |
| HP_ABNORMAL_CONNECTION_OF_THE_CARDIAC_SEGMENTS | HP_ABNORMAL_CONNECTION_OF_THE_CARDIAC_SEGMENTS | HP_ABNORMAL_CONNECTION_OF_THE_CARDIAC_SEGMENTS | 29/1438 | 263/23056 | 0.1102662 | 1.767939 | 3.230414 | 0.0021018 | 0.0105190 | 0.0067623 | MMP23B/HSPG2/PTPN22/NID1/CFAP221/DNAH5/MCIDAS/CCNO/RREB1/GJA1/CITED2/PKD1L1/TMEM270/SHH/ZFPM2/GAS1/NOTCH1/WT1/MYRF/ZIC2/MMP14/DACT1/SALL1/MMP2/FOXF1/GATA6/BMP2/GATA5/GPC4 | 29 |
| GOBP_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | GOBP_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | 11/1438 | 65/23056 | 0.1692308 | 2.713341 | 3.567598 | 0.0021243 | 0.0106163 | 0.0068249 | EDN2/PTGS2/NPNT/ITGA2/ADRB2/EDN1/CAV1/ARHGAP42/SPX/MYOCD/CNN1 | 11 |
| GOBP_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | GOBP_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | GOBP_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | 11/1438 | 65/23056 | 0.1692308 | 2.713341 | 3.567598 | 0.0021243 | 0.0106163 | 0.0068249 | CYP26B1/RBM24/CITED2/NOTCH1/ANKRD1/SIX1/SIX4/FOS/SOX8/NUPR1/MYOCD | 11 |
| GUO_HEX_TARGETS_DN | GUO_HEX_TARGETS_DN | GUO_HEX_TARGETS_DN | 11/1438 | 65/23056 | 0.1692308 | 2.713341 | 3.567598 | 0.0021243 | 0.0106163 | 0.0068249 | TFPI/STAB1/ELL2/ADAM19/RHAG/IFITM3/IGF1/ACTC1/EPB42/CAVIN1/MBP | 11 |
| HP_ACCELERATED_SKELETAL_MATURATION | HP_ACCELERATED_SKELETAL_MATURATION | HP_ACCELERATED_SKELETAL_MATURATION | 11/1438 | 65/23056 | 0.1692308 | 2.713341 | 3.567598 | 0.0021243 | 0.0106163 | 0.0068249 | HSD11B1/PPARG/GLI3/CAV1/CSGALNACT1/TRPS1/FOS/CYP19A1/RNF135/CAVIN1/GPC4 | 11 |
| HP_APLASIA_HYPOPLASIA_AFFECTING_THE_EYE | HP_APLASIA_HYPOPLASIA_AFFECTING_THE_EYE | HP_APLASIA_HYPOPLASIA_AFFECTING_THE_EYE | 43/1438 | 437/23056 | 0.0983982 | 1.577655 | 3.144322 | 0.0021317 | 0.0106492 | 0.0068460 | HSPG2/PTCH2/TBX15/NUAK2/RARB/LAMB2/MITF/FOXL2/FGFRL1/FOXC1/RREB1/TFAP2A/GJA1/GLI3/TMEM270/TSPAN12/SHH/ASPH/GDF6/RSPO2/NOTCH1/PITX3/WT1/ALX4/FZD4/YAP1/WNT10B/GRIP1/FREM2/ZIC2/BMP4/DACT1/LTBP2/FBN1/ALDH1A3/SALL1/LDHD/MAF/RNF135/PIEZO2/COL18A1/ARSL/NDP | 43 |
| BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | BOYLAN_MULTIPLE_MYELOMA_PCA1_UP | 17/1438 | 126/23056 | 0.1349206 | 2.163234 | 3.376793 | 0.0021444 | 0.0107048 | 0.0068817 | IFI16/RASGRP3/JCHAIN/F2RL1/ELL2/TGFBI/HLA-E/IFITM3/MS4A4A/PLAAT3/CCL5/WIPI1/ELANE/C3/FPR1/IL2RB/LPAR4 | 17 |
| GOBP_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | GOBP_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | GOBP_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 17/1438 | 126/23056 | 0.1349206 | 2.163234 | 3.376793 | 0.0021444 | 0.0107048 | 0.0068817 | GFI1/PTPN22/CTSS/RAB7B/NMI/IRAK2/TNIP3/TLR3/F2RL1/TNFAIP3/CD36/CAV1/NLRP6/BIRC3/NFKBIA/IFI35/COLEC12 | 17 |
| GOBP_PRIMARY_ALCOHOL_METABOLIC_PROCESS | GOBP_PRIMARY_ALCOHOL_METABOLIC_PROCESS | GOBP_PRIMARY_ALCOHOL_METABOLIC_PROCESS | 15/1438 | 105/23056 | 0.1428571 | 2.290483 | 3.418222 | 0.0021703 | 0.0108302 | 0.0069624 | DHRS3/RPE65/SULT1E1/DAB2/BMP6/AKR1B10/AKR1B15/TPK1/AKR1C3/ALDH3B1/IGF1/EDNRB/ALDH1A2/ALDH1A3/BMP2 | 15 |
| HP_ABNORMALITY_ON_PULMONARY_FUNCTION_TESTING | HP_ABNORMALITY_ON_PULMONARY_FUNCTION_TESTING | HP_ABNORMALITY_ON_PULMONARY_FUNCTION_TESTING | 18/1438 | 137/23056 | 0.1313869 | 2.106575 | 3.350408 | 0.0021786 | 0.0108676 | 0.0069864 | AGRN/PTPN22/FCGR2A/NLRP3/FGFR3/DOK7/SLC34A2/MCIDAS/TPM2/MYPN/COL13A1/NFKB2/BAG3/SCNN1A/PIEZO2/TGFB1/COL6A2/PDGFB | 18 |
| GOBP_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | GOBP_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | GOBP_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | 9/1438 | 47/23056 | 0.1914894 | 3.070222 | 3.664132 | 0.0022011 | 0.0109519 | 0.0070406 | VCAM1/HMCN1/GRID2/FAT4/CRB2/AMIGO2/ITGA5/ICAM1/TENM1 | 9 |
| HP_ABNORMAL_GLOMERULAR_MESANGIUM_MORPHOLOGY | HP_ABNORMAL_GLOMERULAR_MESANGIUM_MORPHOLOGY | HP_ABNORMAL_GLOMERULAR_MESANGIUM_MORPHOLOGY | 9/1438 | 47/23056 | 0.1914894 | 3.070222 | 3.664132 | 0.0022011 | 0.0109519 | 0.0070406 | FN1/LAMB2/ARHGAP24/CRB2/WT1/MYO1E/APOE/APOL1/TBC1D8B | 9 |
| HP_ABNORMALITY_OF_THE_RADIAL_HEAD | HP_ABNORMALITY_OF_THE_RADIAL_HEAD | HP_ABNORMALITY_OF_THE_RADIAL_HEAD | 9/1438 | 47/23056 | 0.1914894 | 3.070222 | 3.664132 | 0.0022011 | 0.0109519 | 0.0070406 | TBX15/COL5A2/CD96/TENT5A/COL27A1/COL5A1/SMAD6/COL1A1/NOG | 9 |
| HP_CONICAL_TOOTH | HP_CONICAL_TOOTH | HP_CONICAL_TOOTH | 9/1438 | 47/23056 | 0.1914894 | 3.070222 | 3.664132 | 0.0022011 | 0.0109519 | 0.0070406 | TGFA/FGFR3/FGFR2/ALX4/WNT10B/GLI1/NFKBIA/BMP4/DLX4 | 9 |
| RADAEVA_RESPONSE_TO_IFNA1_UP | RADAEVA_RESPONSE_TO_IFNA1_UP | RADAEVA_RESPONSE_TO_IFNA1_UP | 9/1438 | 47/23056 | 0.1914894 | 3.070222 | 3.664132 | 0.0022011 | 0.0109519 | 0.0070406 | IFI44L/VCAM1/HLA-E/HLA-C/IFITM2/IFITM3/IFI35/MX2/MX1 | 9 |
| TSENG_ADIPOGENIC_POTENTIAL_DN | TSENG_ADIPOGENIC_POTENTIAL_DN | TSENG_ADIPOGENIC_POTENTIAL_DN | 9/1438 | 47/23056 | 0.1914894 | 3.070222 | 3.664132 | 0.0022011 | 0.0109519 | 0.0070406 | IL1R1/COL6A3/TGFBI/GJA1/EPHB6/FABP4/NRP1/SIX1/THBD | 9 |
| WP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING_PATHWAY | WP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING_PATHWAY | WP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING_PATHWAY | 9/1438 | 47/23056 | 0.1914894 | 3.070222 | 3.664132 | 0.0022011 | 0.0109519 | 0.0070406 | TEC/CXCL8/IL7R/TSLP/IL6/NFKB2/STAT6/NFKBIA/RELB | 9 |
| HP_ABNORMALITY_OF_THE_KNEE | HP_ABNORMALITY_OF_THE_KNEE | HP_ABNORMALITY_OF_THE_KNEE | 37/1438 | 362/23056 | 0.1022099 | 1.638771 | 3.159353 | 0.0022072 | 0.0109783 | 0.0070576 | HSPG2/PTPN22/NLRP3/COL5A2/FN1/COL6A3/COL7A1/LAMB2/SLCO2A1/FGFR3/NKX3-2/RREB1/RUNX2/COL12A1/TENT5A/GLI3/TMEM270/FLNC/CSGALNACT1/TRPS1/EXT1/TPM2/COL5A1/BAG3/SERPINH1/TNFRSF1A/ITGA7/GLI1/FBN1/CYP19A1/COL1A1/PIEZO2/SCN1B/TGFB1/COL9A3/COL6A2/IL2RB | 37 |
| GOBP_NEURON_APOPTOTIC_PROCESS | GOBP_NEURON_APOPTOTIC_PROCESS | GOBP_NEURON_APOPTOTIC_PROCESS | 27/1438 | 240/23056 | 0.1125000 | 1.803755 | 3.228226 | 0.0022085 | 0.0109810 | 0.0070593 | TGFB2/DLX1/THRB/GRID2/GDNF/TFAP2A/TNFRSF21/SOD2/PTPRZ1/FGF20/ANGPT1/NRP1/FAS/PITX3/NFATC4/SIX1/SIX4/FOXB1/NUPR1/NQO1/IL27RA/MAG/AXL/APOE/PRNP/CEBPB/HMOX1 | 27 |
| HP_PREAXIAL_HAND_POLYDACTYLY | HP_PREAXIAL_HAND_POLYDACTYLY | HP_PREAXIAL_HAND_POLYDACTYLY | 10/1438 | 56/23056 | 0.1785714 | 2.863103 | 3.600156 | 0.0022098 | 0.0109835 | 0.0070609 | FGFRL1/TFAP2A/GJA1/GLI3/SHH/FGFR2/GLI1/BMP4/DACT1/SALL1 | 10 |
| GOBP_REGULATION_OF_PROTEIN_SECRETION | GOBP_REGULATION_OF_PROTEIN_SECRETION | GOBP_REGULATION_OF_PROTEIN_SECRETION | 28/1438 | 252/23056 | 0.1111111 | 1.781487 | 3.217144 | 0.0022214 | 0.0110372 | 0.0070954 | C1QTNF12/TGFB2/IL1A/IL1B/PPARG/VEGFC/F2RL1/PCSK1/BMP6/ADTRP/IL6/ADAM9/ADCY8/ALOX5/ANKRD1/TCF7L2/SAA1/KCNA5/IGF1/RHBDF1/CCL5/GIP/LLGL2/RHBDF2/MYOM1/TGFB1/KCNN4/APOE | 28 |
| GOBP_RESPONSE_TO_RADIATION | GOBP_RESPONSE_TO_RADIATION | GOBP_RESPONSE_TO_RADIATION | 43/1438 | 438/23056 | 0.0981735 | 1.574053 | 3.128358 | 0.0022252 | 0.0110518 | 0.0071048 | RPE65/VCAM1/IFI16/PTGS2/PTPRC/IL1A/ITGB6/COL3A1/NABP1/BHLHE40/HRH1/MME/CDS1/TRPC3/SLC7A11/PTPRK/SOD2/HOXA1/AQP1/EXT1/ANXA1/CABP4/YAP1/MMP1/MMP3/CARD16/CRYAB/CACNA2D4/HMGA2/NFATC4/FOS/SLC24A4/CRIP1/BMF/FOXB1/MMP2/GNGT2/TNFRSF11A/ELANE/BCL3/LRRN4/THBD/GUCY2F | 43 |
| GOBP_CARDIAC_MUSCLE_CELL_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_CONTRACTION | 12/1438 | 75/23056 | 0.1600000 | 2.565341 | 3.501945 | 0.0022309 | 0.0110720 | 0.0071178 | KCNE4/DSP/GJA1/CAV1/STC1/GSN/KCNA5/HCN4/JUP/KCNJ2/DSG2/SCN1B | 12 |
| GOBP_LYMPHOCYTE_APOPTOTIC_PROCESS | GOBP_LYMPHOCYTE_APOPTOTIC_PROCESS | GOBP_LYMPHOCYTE_APOPTOTIC_PROCESS | 12/1438 | 75/23056 | 0.1600000 | 2.565341 | 3.501945 | 0.0022309 | 0.0110720 | 0.0071178 | WNT5A/BCL6/IL7R/TNFRSF21/GLI3/IDO1/ST3GAL1/CD274/FAS/BMP4/CCL5/BIRC7 | 12 |
| GOBP_CELLULAR_RESPONSE_TO_VIRUS | GOBP_CELLULAR_RESPONSE_TO_VIRUS | GOBP_CELLULAR_RESPONSE_TO_VIRUS | 13/1438 | 85/23056 | 0.1529412 | 2.452164 | 3.459309 | 0.0022616 | 0.0112083 | 0.0072054 | ZC3H12A/IKBKE/NLRP3/DDX60/TLR3/IL6/EXT1/DDX58/BIRC3/OASL/RNF135/CCL5/DHX58 | 13 |
| GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | GOBP_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 13/1438 | 85/23056 | 0.1529412 | 2.452164 | 3.459309 | 0.0022616 | 0.0112083 | 0.0072054 | CASP8/SP100/TNFAIP3/SERPINE1/TNFRSF10C/TNFRSF10A/ITPRIP/BAG3/TNFRSF1A/THBS1/TMC8/ICAM1/HMOX1 | 13 |
| GOBP_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS | GOBP_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS | GOBP_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS | 13/1438 | 85/23056 | 0.1529412 | 2.452164 | 3.459309 | 0.0022616 | 0.0112083 | 0.0072054 | LDLRAP1/AGT/PLA2G7/CD36/MSR1/APOC3/APOA1/SOAT2/ANXA2/CETP/LIPG/APOE/HMOX1 | 13 |
| SMID_BREAST_CANCER_LUMINAL_A_UP | SMID_BREAST_CANCER_LUMINAL_A_UP | SMID_BREAST_CANCER_LUMINAL_A_UP | 13/1438 | 85/23056 | 0.1529412 | 2.452164 | 3.459309 | 0.0022616 | 0.0112083 | 0.0072054 | LMOD1/PPARG/LAMA2/PTN/FABP4/COL14A1/PCSK5/PGR/ITGA7/IGF1/HOXB2/ABCA8/RUNX1 | 13 |
| KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION | 16/1438 | 116/23056 | 0.1379310 | 2.211501 | 3.373729 | 0.0022733 | 0.0112621 | 0.0072400 | VCAM1/RASSF5/ITGA4/CLDN1/CLDN16/TXK/MYL7/VCL/CLDN6/MMP2/CLDN7/PECAM1/ICAM1/MYL9/RAC2/MSN | 16 |
| GOBP_ADHESION_OF_SYMBIONT_TO_HOST | GOBP_ADHESION_OF_SYMBIONT_TO_HOST | GOBP_ADHESION_OF_SYMBIONT_TO_HOST | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | LRRC15/SFTPD/CLEC4M/ICAM1/NECTIN2 | 5 |
| GOBP_AROMATIC_AMINO_ACID_FAMILY_CATABOLIC_PROCESS | GOBP_AROMATIC_AMINO_ACID_FAMILY_CATABOLIC_PROCESS | GOBP_AROMATIC_AMINO_ACID_FAMILY_CATABOLIC_PROCESS | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | KYNU/TDO2/IDO1/HPD/IL4I1 | 5 |
| GOBP_CARDIAC_NEURAL_CREST_CELL_DIFFERENTIATION_INVOLVED_IN_HEART_DEVELOPMENT | GOBP_CARDIAC_NEURAL_CREST_CELL_DIFFERENTIATION_INVOLVED_IN_HEART_DEVELOPMENT | GOBP_CARDIAC_NEURAL_CREST_CELL_DIFFERENTIATION_INVOLVED_IN_HEART_DEVELOPMENT | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | HES1/EDN1/CITED2/SEMA3C/BMP4 | 5 |
| GOBP_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING | GOBP_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING | GOBP_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_REMODELING | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | APOC3/APOA1/CETP/LIPG/APOE | 5 |
| GOBP_NEUTROPHIL_HOMEOSTASIS | GOBP_NEUTROPHIL_HOMEOSTASIS | GOBP_NEUTROPHIL_HOMEOSTASIS | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | ITPKB/SLC7A11/IL6/ANXA1/AXL | 5 |
| GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_DISASSEMBLY | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_DISASSEMBLY | GOBP_REGULATION_OF_EXTRACELLULAR_MATRIX_DISASSEMBLY | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | DPP4/FAP/DDR1/IL6/TGFB1 | 5 |
| GOBP_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | DHRS3/CYP26B1/AKR1C3/CYP26A1/KLF2 | 5 |
| GOBP_REGULATION_OF_VASCULOGENESIS | GOBP_REGULATION_OF_VASCULOGENESIS | GOBP_REGULATION_OF_VASCULOGENESIS | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | CD34/KDR/ADM/RRAS/RIN2 | 5 |
| GOBP_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE | GOBP_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE | GOBP_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY_INVOLVED_IN_NEURON_PROJECTION_GUIDANCE | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | ECE1/NRP2/EDN1/SEMA3A/NRP1 | 5 |
| GOMF_WNT_ACTIVATED_RECEPTOR_ACTIVITY | GOMF_WNT_ACTIVATED_RECEPTOR_ACTIVITY | GOMF_WNT_ACTIVATED_RECEPTOR_ACTIVITY | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | FZD1/TSPAN12/FZD6/FZD8/FZD4 | 5 |
| HP_PHARYNGITIS | HP_PHARYNGITIS | HP_PHARYNGITIS | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | GFI1/PTPN22/NFKB2/TNFRSF1A/ELANE | 5 |
| HP_YELLOW_WHITE_LESIONS_OF_THE_MACULA | HP_YELLOW_WHITE_LESIONS_OF_THE_MACULA | HP_YELLOW_WHITE_LESIONS_OF_THE_MACULA | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | HMCN1/CFH/EFEMP1/CFI/APOE | 5 |
| LUI_THYROID_CANCER_CLUSTER_5 | LUI_THYROID_CANCER_CLUSTER_5 | LUI_THYROID_CANCER_CLUSTER_5 | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | AQP7/CRYAB/BLVRB/LGALS1/SSX1 | 5 |
| MAINA_VHL_TARGETS_DN | MAINA_VHL_TARGETS_DN | MAINA_VHL_TARGETS_DN | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | BHLHE40/SPARC/CCN2/MAF/SLC16A3 | 5 |
| VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN | VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN | VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | SP100/PHLDA2/MMP1/ARHGDIB/NQO1 | 5 |
| WP_QUERCETIN_AND_NFKB_AP1_INDUCED_APOPTOSIS | WP_QUERCETIN_AND_NFKB_AP1_INDUCED_APOPTOSIS | WP_QUERCETIN_AND_NFKB_AP1_INDUCED_APOPTOSIS | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | PTGS2/MAFK/MMP1/NFKBIA/FOS | 5 |
| WU_HBX_TARGETS_1_UP | WU_HBX_TARGETS_1_UP | WU_HBX_TARGETS_1_UP | 5/1438 | 16/23056 | 0.3125000 | 5.010431 | 4.138701 | 0.0022922 | 0.0112867 | 0.0072558 | CXCL1/IL6/FAS/MMP1/CASP4 | 5 |
| BIOCARTA_SODD_PATHWAY | BIOCARTA_SODD_PATHWAY | BIOCARTA_SODD_PATHWAY | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | TNFRSF1B/CASP8/BIRC3/TNFRSF1A | 4 |
| FREDERICK_PRKCI_TARGETS | FREDERICK_PRKCI_TARGETS | FREDERICK_PRKCI_TARGETS | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | KYNU/PHLDB2/STC1/MMP10 | 4 |
| GOBP_DENDRITE_ARBORIZATION | GOBP_DENDRITE_ARBORIZATION | GOBP_DENDRITE_ARBORIZATION | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | TPBG/SEMA3A/PTN/NRP1 | 4 |
| GOBP_DESMOSOME_ORGANIZATION | GOBP_DESMOSOME_ORGANIZATION | GOBP_DESMOSOME_ORGANIZATION | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | DSP/PERP/JUP/DSG2 | 4 |
| GOBP_EPITHELIAL_FLUID_TRANSPORT | GOBP_EPITHELIAL_FLUID_TRANSPORT | GOBP_EPITHELIAL_FLUID_TRANSPORT | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | CSF2/EDN1/AQP1/EDNRB | 4 |
| GOBP_HYPOTHALAMUS_CELL_DIFFERENTIATION | GOBP_HYPOTHALAMUS_CELL_DIFFERENTIATION | GOBP_HYPOTHALAMUS_CELL_DIFFERENTIATION | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | NRP2/SEMA3A/NRP1/HAP1 | 4 |
| GOBP_IMMATURE_T_CELL_PROLIFERATION | GOBP_IMMATURE_T_CELL_PROLIFERATION | GOBP_IMMATURE_T_CELL_PROLIFERATION | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | IL1A/IL1B/SHH/BMP4 | 4 |
| GOBP_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | GOBP_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | GOBP_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | PTPRC/IL7R/KLRD1/NCKAP1L | 4 |
| GOBP_POSITIVE_REGULATION_OF_T_CELL_DIFFERENTIATION_IN_THYMUS | GOBP_POSITIVE_REGULATION_OF_T_CELL_DIFFERENTIATION_IN_THYMUS | GOBP_POSITIVE_REGULATION_OF_T_CELL_DIFFERENTIATION_IN_THYMUS | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | IL7R/VNN1/SHH/TESPA1 | 4 |
| GOBP_REGULATION_OF_CEREBELLAR_GRANULE_CELL_PRECURSOR_PROLIFERATION | GOBP_REGULATION_OF_CEREBELLAR_GRANULE_CELL_PRECURSOR_PROLIFERATION | GOBP_REGULATION_OF_CEREBELLAR_GRANULE_CELL_PRECURSOR_PROLIFERATION | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | EGF/SHH/GLI1/LHX1 | 4 |
| GOBP_REGULATION_OF_CHRONIC_INFLAMMATORY_RESPONSE | GOBP_REGULATION_OF_CHRONIC_INFLAMMATORY_RESPONSE | GOBP_REGULATION_OF_CHRONIC_INFLAMMATORY_RESPONSE | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | TNFAIP3/IDO1/CYP19A1/CCL5 | 4 |
| GOBP_REGULATION_OF_TOLL_LIKE_RECEPTOR_3_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TOLL_LIKE_RECEPTOR_3_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TOLL_LIKE_RECEPTOR_3_SIGNALING_PATHWAY | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | PTPN22/F2RL1/TNFAIP3/CAV1 | 4 |
| GOBP_VIRION_ATTACHMENT_TO_HOST_CELL | GOBP_VIRION_ATTACHMENT_TO_HOST_CELL | GOBP_VIRION_ATTACHMENT_TO_HOST_CELL | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | LRRC15/CLEC4M/ICAM1/NECTIN2 | 4 |
| GOCC_MHC_CLASS_I_PROTEIN_COMPLEX | GOCC_MHC_CLASS_I_PROTEIN_COMPLEX | GOCC_MHC_CLASS_I_PROTEIN_COMPLEX | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | MR1/HFE/HLA-E/HLA-C | 4 |
| GOMF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | GOMF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | GOMF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | CASP10/CASP8/CASP4/CASP1 | 4 |
| GOMF_DEOXYCYTIDINE_DEAMINASE_ACTIVITY | GOMF_DEOXYCYTIDINE_DEAMINASE_ACTIVITY | GOMF_DEOXYCYTIDINE_DEAMINASE_ACTIVITY | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | CDA/APOBEC3A/APOBEC3G/APOBEC3H | 4 |
| HOFFMAN_CLOCK_TARGETS_UP | HOFFMAN_CLOCK_TARGETS_UP | HOFFMAN_CLOCK_TARGETS_UP | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | HOXA7/CD36/TNFRSF11B/ANXA1 | 4 |
| HP_ABNORMALITY_OF_THE_UTERINE_CERVIX | HP_ABNORMALITY_OF_THE_UTERINE_CERVIX | HP_ABNORMALITY_OF_THE_UTERINE_CERVIX | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | COL3A1/COL5A2/COL5A1/COL1A1 | 4 |
| HP_APLASIA_HYPOPLASIA_OF_THE_EPIGLOTTIS | HP_APLASIA_HYPOPLASIA_OF_THE_EPIGLOTTIS | HP_APLASIA_HYPOPLASIA_OF_THE_EPIGLOTTIS | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | PRRX1/FGFR3/GLI3/FGFR2 | 4 |
| HP_ERYSIPELAS | HP_ERYSIPELAS | HP_ERYSIPELAS | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | ADAMTS3/FAT4/VEGFC/TNFRSF1A | 4 |
| HP_RADIAL_DEVIATION_OF_THE_HAND | HP_RADIAL_DEVIATION_OF_THE_HAND | HP_RADIAL_DEVIATION_OF_THE_HAND | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | GLI3/SAMD9/COL9A3/BGN | 4 |
| HP_RETINAL_NEOVASCULARIZATION | HP_RETINAL_NEOVASCULARIZATION | HP_RETINAL_NEOVASCULARIZATION | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | TSPAN12/LRRC32/FZD4/NDP | 4 |
| HP_SHOCK | HP_SHOCK | HP_SHOCK | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | DSP/TRDN/SCNN1A/JUP | 4 |
| HP_SYSTOLIC_HEART_MURMUR | HP_SYSTOLIC_HEART_MURMUR | HP_SYSTOLIC_HEART_MURMUR | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | GJA1/CITED2/ACTC1/GATA6 | 4 |
| MAINA_VHL_TARGETS_UP | MAINA_VHL_TARGETS_UP | MAINA_VHL_TARGETS_UP | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | DAB2/TAGLN/CNN1/MYL9 | 4 |
| MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY | MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY | MIKKELSEN_PARTIALLY_REPROGRAMMED_TO_PLURIPOTENCY | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | FOXD1/TFAP2A/PERP/CDH13 | 4 |
| OSAWA_TNF_TARGETS | OSAWA_TNF_TARGETS | OSAWA_TNF_TARGETS | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | COL3A1/CXCL8/IER3/TNFAIP2 | 4 |
| RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_UP | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_UP | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_SMAD4_UP | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | BCL6/TNFAIP3/BMF/TGFB1 | 4 |
| WP_LIPID_PARTICLES_COMPOSITION | WP_LIPID_PARTICLES_COMPOSITION | WP_LIPID_PARTICLES_COMPOSITION | 4/1438 | 10/23056 | 0.4000000 | 6.413352 | 4.415936 | 0.0023342 | 0.0113708 | 0.0073099 | APOC3/APOA1/CETP/APOE | 4 |
| HP_ABNORMAL_METACARPAL_MORPHOLOGY | HP_ABNORMAL_METACARPAL_MORPHOLOGY | HP_ABNORMAL_METACARPAL_MORPHOLOGY | 20/1438 | 160/23056 | 0.1250000 | 2.004173 | 3.287326 | 0.0023379 | 0.0113708 | 0.0073099 | PTCH2/PRG4/TWIST2/CD96/FGFR3/FAT4/SPARC/RUNX2/GLI3/SHH/TRPS1/EXT1/MMP14/FBN1/MMP2/NOG/KCNJ2/BMP2/COL9A3/BGN | 20 |
| HP_IMMUNOLOGIC_HYPERSENSITIVITY | HP_IMMUNOLOGIC_HYPERSENSITIVITY | HP_IMMUNOLOGIC_HYPERSENSITIVITY | 20/1438 | 160/23056 | 0.1250000 | 2.004173 | 3.287326 | 0.0023379 | 0.0113708 | 0.0073099 | FCGR2A/HNMT/CASP8/ADRB2/RREB1/PLA2G7/SHH/PLAG1/GAS1/TNFSF15/ALOX5/FAS/NFKB2/HMGA2/ZIC2/IL4R/IL12RB1/TGFB1/RUNX1/ARSL | 20 |
| GOBP_FOREBRAIN_REGIONALIZATION | GOBP_FOREBRAIN_REGIONALIZATION | GOBP_FOREBRAIN_REGIONALIZATION | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | GLI3/SHH/BMP4/LHX1/BMP2/WNT7B | 6 |
| GOBP_HYPOTHALAMUS_DEVELOPMENT | GOBP_HYPOTHALAMUS_DEVELOPMENT | GOBP_HYPOTHALAMUS_DEVELOPMENT | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | SRD5A2/NRP2/SEMA3A/NRP1/FOXB1/HAP1 | 6 |
| GOBP_LIVER_MORPHOGENESIS | GOBP_LIVER_MORPHOGENESIS | GOBP_LIVER_MORPHOGENESIS | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | TGFA/TNFAIP3/IL6/PTN/GLI1/CEBPB | 6 |
| GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD | GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD | GOBP_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | WNT5A/SHH/SULF1/FGFR2/BMP4/NOG | 6 |
| GOMF_SEMAPHORIN_RECEPTOR_BINDING | GOMF_SEMAPHORIN_RECEPTOR_BINDING | GOMF_SEMAPHORIN_RECEPTOR_BINDING | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | SEMA3B/SEMA5A/SEMA3C/SEMA3A/SEMA3D/SEMA6B | 6 |
| HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | CD53/MITF/NT5E/TNFRSF11B/POSTN/MAF | 6 |
| HP_REDUCED_FORCED_VITAL_CAPACITY | HP_REDUCED_FORCED_VITAL_CAPACITY | HP_REDUCED_FORCED_VITAL_CAPACITY | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | FCGR2A/MCIDAS/TPM2/BAG3/TGFB1/COL6A2 | 6 |
| WP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING | WP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING | WP_PHOTODYNAMIC_THERAPYINDUCED_NFE2L2_NRF2_SURVIVAL_SIGNALING | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | ABCG2/FOS/CES1/NQO1/ABCC3/HMOX1 | 6 |
| YAN_ESCAPE_FROM_ANOIKIS | YAN_ESCAPE_FROM_ANOIKIS | YAN_ESCAPE_FROM_ANOIKIS | 6/1438 | 23/23056 | 0.2608696 | 4.182621 | 3.938472 | 0.0023424 | 0.0113708 | 0.0073099 | VCAM1/IL15/CD44/MMP2/CCL5/MX1 | 6 |
| HP_OSTEOPENIA | HP_OSTEOPENIA | HP_OSTEOPENIA | 29/1438 | 265/23056 | 0.1094340 | 1.754596 | 3.186472 | 0.0023527 | 0.0114165 | 0.0073393 | GFI1/ADCY10/COL5A2/COL7A1/SGMS2/FAT4/ADAMTS2/TENT5A/SIM1/TMEM270/TRPS1/GLIS3/COL5A1/FGFR2/CREB3L1/SERPINH1/MMP1/IGF1/SLC7A7/MMP14/PYGL/FBN1/CYP19A1/BNC1/MMP2/CAVIN1/COL1A1/ELANE/PLS3 | 29 |
| HP_OLIGOHYDRAMNIOS | HP_OLIGOHYDRAMNIOS | HP_OLIGOHYDRAMNIOS | 19/1438 | 149/23056 | 0.1275168 | 2.044525 | 3.298998 | 0.0023619 | 0.0114535 | 0.0073631 | AGT/ACTG2/MYLK/DSP/RHAG/BMPER/GLI3/FGF20/PLAG1/ITGA8/ALX4/EFEMP2/HMGA2/FBLN5/FBN1/LHX1/JUP/GATA6/MYL9 | 19 |
| GOBP_CARDIAC_MUSCLE_CONTRACTION | GOBP_CARDIAC_MUSCLE_CONTRACTION | GOBP_CARDIAC_MUSCLE_CONTRACTION | 18/1438 | 138/23056 | 0.1304348 | 2.091310 | 3.316299 | 0.0023628 | 0.0114535 | 0.0073631 | ZC3H12A/BMP10/KCNE4/TNNC1/DSP/GJA1/CCN2/CAV1/STC1/GSN/KCNA5/TPM1/HCN4/JUP/MYL4/KCNJ2/DSG2/SCN1B | 18 |
| HP_ABNORMAL_VENOUS_MORPHOLOGY | HP_ABNORMAL_VENOUS_MORPHOLOGY | HP_ABNORMAL_VENOUS_MORPHOLOGY | 18/1438 | 138/23056 | 0.1304348 | 2.091310 | 3.316299 | 0.0023628 | 0.0114535 | 0.0073631 | CFAP221/COL3A1/PPARG/VEGFC/DNAH5/MCIDAS/CCNO/RREB1/EPHB4/CAV1/TEK/WT1/ALX4/FOS/FOXF1/PIEZO1/CAVIN1/NDP | 18 |
| GOBP_NEGATIVE_REGULATION_OF_HEMOPOIESIS | GOBP_NEGATIVE_REGULATION_OF_HEMOPOIESIS | GOBP_NEGATIVE_REGULATION_OF_HEMOPOIESIS | 15/1438 | 106/23056 | 0.1415094 | 2.268874 | 3.377027 | 0.0023855 | 0.0115515 | 0.0074260 | RUNX3/ZC3H12A/BCL6/TLR3/HOXA7/INHBA/GLI3/SHH/ANXA1/UBASH3B/BMP4/FBN1/IL4R/FSTL3/RUNX1 | 15 |
| WANG_HCP_PROSTATE_CANCER | WANG_HCP_PROSTATE_CANCER | WANG_HCP_PROSTATE_CANCER | 15/1438 | 106/23056 | 0.1415094 | 2.268874 | 3.377027 | 0.0023855 | 0.0115515 | 0.0074260 | FN1/WNT5A/P3H2/CCDC69/CITED2/FLNC/B4GALT1/CLIC3/HTRA1/AHNAK/EFEMP2/CRIP1/MSLN/GADD45B/SIM2 | 15 |
| WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY | WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY | WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY | 15/1438 | 106/23056 | 0.1415094 | 2.268874 | 3.377027 | 0.0023855 | 0.0115515 | 0.0074260 | WNT5A/LEF1/NKD2/FZD1/FZD6/FZD8/PLAU/TCF7L2/CD44/FOSL1/FZD4/WNT10B/PRKD1/ESRRB/WNT7B | 15 |
| REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | 33/1438 | 314/23056 | 0.1050955 | 1.685037 | 3.152235 | 0.0023891 | 0.0115647 | 0.0074345 | TAS1R1/HTR1D/PLA2G4A/AGT/ACKR3/CCR3/SUCNR1/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/GPSM3/ITPR3/PDE1C/GPR37/PNOC/ADCY8/ANXA1/S1PR3/NPY4R/SAA1/C3AR1/HCAR1/BDKRB1/CCL5/CCR7/GNGT2/C3/S1PR5/C5AR1/FPR1 | 33 |
| HP_ABNORMALITY_OF_THE_URETHRA | HP_ABNORMALITY_OF_THE_URETHRA | HP_ABNORMALITY_OF_THE_URETHRA | 42/1438 | 427/23056 | 0.0983607 | 1.577054 | 3.104215 | 0.0024000 | 0.0116136 | 0.0074660 | MMP23B/HSPG2/LAMC2/LAMB3/TMEM63A/SRD5A2/ITGA6/COL3A1/COL7A1/WNT5A/PLD1/FGFRL1/FGFR3/FAT4/FOXC1/RREB1/TFAP2A/GLI3/TMEM270/SAMD9/PLAG1/ZFPM2/COLEC10/FGFR2/WT1/EFEMP2/MMP1/GLI1/HMGA2/GRIP1/FREM2/BMP4/DACT1/FBLN5/SALL1/FOXF1/SOX9/ITGB4/PIEZO2/RIN2/MID1/GPC4 | 42 |
| GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 11/1438 | 66/23056 | 0.1666667 | 2.672230 | 3.508752 | 0.0024083 | 0.0116496 | 0.0074891 | RUNX3/ZC3H12A/NLRP3/TGFBR2/BCL6/CD274/ANXA1/NCKAP1L/IL4R/IL12RB1/RUNX1 | 11 |
| CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP | CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP | CASORELLI_APL_SECONDARY_VS_DE_NOVO_UP | 8/1438 | 39/23056 | 0.2051282 | 3.288898 | 3.689680 | 0.0024329 | 0.0117435 | 0.0075495 | NID1/TGFA/CSGALNACT1/CLU/KLF4/PLAAT3/FOS/SLFN12 | 8 |
| GOBP_AMYLOID_BETA_CLEARANCE | GOBP_AMYLOID_BETA_CLEARANCE | GOBP_AMYLOID_BETA_CLEARANCE | 8/1438 | 39/23056 | 0.2051282 | 3.288898 | 3.689680 | 0.0024329 | 0.0117435 | 0.0075495 | MME/CD36/MSR1/CLU/MYOCD/C3/APOE/C5AR1 | 8 |
| GOBP_RESPONSE_TO_PROGESTERONE | GOBP_RESPONSE_TO_PROGESTERONE | GOBP_RESPONSE_TO_PROGESTERONE | 8/1438 | 39/23056 | 0.2051282 | 3.288898 | 3.689680 | 0.0024329 | 0.0117435 | 0.0075495 | TGFB2/CAV1/FOSL1/YAP1/FOS/THBS1/MBP/TGFB1 | 8 |
| HEIDENBLAD_AMPLICON_8Q24_DN | HEIDENBLAD_AMPLICON_8Q24_DN | HEIDENBLAD_AMPLICON_8Q24_DN | 8/1438 | 39/23056 | 0.2051282 | 3.288898 | 3.689680 | 0.0024329 | 0.0117435 | 0.0075495 | LPP/NEK6/MMRN2/MYOF/PYROXD2/FZD4/SLC14A1/KCNN4 | 8 |
| HP_ABNORMAL_LUNG_LOBATION | HP_ABNORMAL_LUNG_LOBATION | HP_ABNORMAL_LUNG_LOBATION | 8/1438 | 39/23056 | 0.2051282 | 3.288898 | 3.689680 | 0.0024329 | 0.0117435 | 0.0075495 | RREB1/GLI3/RSPO2/WT1/GRIP1/FREM2/FOXF1/GPC4 | 8 |
| SPIRA_SMOKERS_LUNG_CANCER_UP | SPIRA_SMOKERS_LUNG_CANCER_UP | SPIRA_SMOKERS_LUNG_CANCER_UP | 8/1438 | 39/23056 | 0.2051282 | 3.288898 | 3.689680 | 0.0024329 | 0.0117435 | 0.0075495 | PLA2G4A/SLC4A4/CXCL8/CXCL2/ANXA3/FOS/SERPINA1/SOX9 | 8 |
| GOBP_NEURON_PROJECTION_EXTENSION | GOBP_NEURON_PROJECTION_EXTENSION | GOBP_NEURON_PROJECTION_EXTENSION | 21/1438 | 172/23056 | 0.1220930 | 1.957564 | 3.251024 | 0.0024650 | 0.0118943 | 0.0076465 | EDN2/ITGA4/NRP2/FN1/LAMB2/SEMA3B/WNT5A/OSTN/SLIT2/SEMA5A/EDN1/DDR1/SEMA3C/SEMA3A/SEMA3D/NRP1/VCL/TRPV2/SEMA6B/MAG/APOE | 21 |
| GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | 16/1438 | 117/23056 | 0.1367521 | 2.192599 | 3.335449 | 0.0024844 | 0.0119778 | 0.0077001 | CSF1/CASP8/MITF/LEF1/TLR3/HOXA7/INHBA/UBASH3B/ZFP36L1/FOS/FBN1/FSTL3/TGFB1/CEBPB/RUNX1/LIF | 16 |
| WP_WNT_SIGNALING | WP_WNT_SIGNALING | WP_WNT_SIGNALING | 16/1438 | 117/23056 | 0.1367521 | 2.192599 | 3.335449 | 0.0024844 | 0.0119778 | 0.0077001 | WNT5A/PRICKLE2/LEF1/NKD2/FZD1/FZD6/FZD8/DKK1/PLAU/TCF7L2/FOSL1/WNT10B/NFATC4/NFATC2/WNT7B/GPC4 | 16 |
| HP_ABNORMALITY_OF_DENTAL_ERUPTION | HP_ABNORMALITY_OF_DENTAL_ERUPTION | HP_ABNORMALITY_OF_DENTAL_ERUPTION | 27/1438 | 242/23056 | 0.1115702 | 1.788848 | 3.181666 | 0.0024849 | 0.0119778 | 0.0077001 | TGFA/TWIST2/WNT5A/FGFR3/ADAMTS3/FAT4/DSP/RUNX2/TENT5A/GJA1/FAM20C/GLI3/TRPS1/FGFR2/WNT10B/GLI1/IGF1/BMP4/MMP2/KRT17/JUP/DLX4/KCNJ2/TNFRSF11A/TGFB1/FRMPD4/ARHGEF6 | 27 |
| HP_ABNORMAL_CIRCULATING_IGG_LEVEL | HP_ABNORMAL_CIRCULATING_IGG_LEVEL | HP_ABNORMAL_CIRCULATING_IGG_LEVEL | 12/1438 | 76/23056 | 0.1578947 | 2.531586 | 3.449272 | 0.0025019 | 0.0120510 | 0.0077472 | CASP10/CASP8/SP110/IL7R/STING1/PSMB8/FAS/NFKB2/NCKAP1L/TNFRSF11A/TGFB1/RAC2 | 12 |
| LEIN_OLIGODENDROCYTE_MARKERS | LEIN_OLIGODENDROCYTE_MARKERS | LEIN_OLIGODENDROCYTE_MARKERS | 12/1438 | 76/23056 | 0.1578947 | 2.531586 | 3.449272 | 0.0025019 | 0.0120510 | 0.0077472 | S100A16/TMEM63A/SERPINB1/MOG/GPR37/GSN/MYRF/CRYAB/ACTC1/MBP/S1PR5/MAG | 12 |
| COATES_MACROPHAGE_M1_VS_M2_UP | COATES_MACROPHAGE_M1_VS_M2_UP | COATES_MACROPHAGE_M1_VS_M2_UP | 13/1438 | 86/23056 | 0.1511628 | 2.423650 | 3.411351 | 0.0025154 | 0.0121122 | 0.0077865 | CFH/CRIM1/TGFBI/OGFRL1/GJA1/MSR1/PLAAT3/SLCO2B1/SLC7A7/MAF/ABCA9/COLEC12/AXL | 13 |
| GOBP_ENDOCARDIAL_CUSHION_FORMATION | GOBP_ENDOCARDIAL_CUSHION_FORMATION | GOBP_ENDOCARDIAL_CUSHION_FORMATION | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | TGFB2/TGFBR2/NOTCH1/BMP4/NOG/TGFB1/BMP2 | 7 |
| GOBP_MUSCLE_HYPERTROPHY_IN_RESPONSE_TO_STRESS | GOBP_MUSCLE_HYPERTROPHY_IN_RESPONSE_TO_STRESS | GOBP_MUSCLE_HYPERTROPHY_IN_RESPONSE_TO_STRESS | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | ERRFI1/ATP2B4/BMP10/PPARG/TRPC3/FOXO1/GATA6 | 7 |
| GOBP_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | RUNX3/ZC3H12A/BCL6/CD274/ANXA1/IL4R/RUNX1 | 7 |
| GOBP_PEPTIDE_CATABOLIC_PROCESS | GOBP_PEPTIDE_CATABOLIC_PROCESS | GOBP_PEPTIDE_CATABOLIC_PROCESS | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | ECE1/ERAP2/LVRN/ANPEP/GGTLC3/GGTLC2/GGT1 | 7 |
| GOBP_POSITIVE_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING | GOBP_POSITIVE_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING | GOBP_POSITIVE_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | IL6/AJUBA/BMP4/MYOCD/WTIP/ZFP36/TGFB1 | 7 |
| GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | GOBP_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | EDN2/PTGS2/NPNT/ITGA2/EDN1/SPX/MYOCD | 7 |
| GOBP_TRIGLYCERIDE_CATABOLIC_PROCESS | GOBP_TRIGLYCERIDE_CATABOLIC_PROCESS | GOBP_TRIGLYCERIDE_CATABOLIC_PROCESS | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | CPS1/MGLL/AADAC/APOC3/APOA1/LIPG/PNPLA3 | 7 |
| GOMF_TUMOR_NECROSIS_FACTOR_RECEPTOR_BINDING | GOMF_TUMOR_NECROSIS_FACTOR_RECEPTOR_BINDING | GOMF_TUMOR_NECROSIS_FACTOR_RECEPTOR_BINDING | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | CASP8/TNFSF15/TRAF1/TNFSF13B/TNFSF9/CD70/TNFSF14 | 7 |
| HP_ABNORMALITY_OF_HAND_JOINT_MOBILITY | HP_ABNORMALITY_OF_HAND_JOINT_MOBILITY | HP_ABNORMALITY_OF_HAND_JOINT_MOBILITY | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | COL3A1/COL6A3/COL12A1/CSGALNACT1/COL5A1/FBN1/COL6A2 | 7 |
| HP_POLYGENIC_INHERITANCE | HP_POLYGENIC_INHERITANCE | HP_POLYGENIC_INHERITANCE | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | CFH/PPARG/ADRB2/SERPINH1/FLT3/BMP4/APOL1 | 7 |
| JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | CLU/FABP4/CD82/GPRC5A/MT2A/SERPINB2/SAT1 | 7 |
| PID_AVB3_OPN_PATHWAY | PID_AVB3_OPN_PATHWAY | PID_AVB3_OPN_PATHWAY | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | SPP1/GSN/PLAU/CD44/NFKBIA/FOS/MMP2 | 7 |
| REACTOME_NICOTINATE_METABOLISM | REACTOME_NICOTINATE_METABOLISM | REACTOME_NICOTINATE_METABOLISM | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | PTGS2/PARP14/NT5E/PARP10/RNLS/NNMT/PTGIS | 7 |
| WP_PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM_IN_SENESCENCE | WP_PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM_IN_SENESCENCE | WP_PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM_IN_SENESCENCE | 7/1438 | 31/23056 | 0.2258065 | 3.620441 | 3.765387 | 0.0025297 | 0.0121201 | 0.0077916 | PTGS2/PLA2G4A/PTGS1/ALOX5/ALOX5AP/PTGIS/CYSLTR1 | 7 |
| GOBP_INTERFERON_BETA_PRODUCTION | GOBP_INTERFERON_BETA_PRODUCTION | GOBP_INTERFERON_BETA_PRODUCTION | 10/1438 | 57/23056 | 0.1754386 | 2.812874 | 3.534311 | 0.0025330 | 0.0121201 | 0.0077916 | NMI/TLR3/STING1/TRIM38/TRIM56/DDX58/RNF135/DHX58/RELB/SIRPA | 10 |
| GOBP_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE | GOBP_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE | GOBP_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE | 10/1438 | 57/23056 | 0.1754386 | 2.812874 | 3.534311 | 0.0025330 | 0.0121201 | 0.0077916 | RPE65/IGFN1/THRB/TFAP2A/TSPAN12/CRB2/CABP4/SOX8/LHX1/SOX9 | 10 |
| HP_ABNORMALITY_OF_UPPER_LIMB_EPIPHYSIS_MORPHOLOGY | HP_ABNORMALITY_OF_UPPER_LIMB_EPIPHYSIS_MORPHOLOGY | HP_ABNORMALITY_OF_UPPER_LIMB_EPIPHYSIS_MORPHOLOGY | 10/1438 | 57/23056 | 0.1754386 | 2.812874 | 3.534311 | 0.0025330 | 0.0121201 | 0.0077916 | FGFRL1/FGFR3/NKX3-2/RUNX2/TRPS1/EXT1/SALL1/COL9A3/ARSL/BGN | 10 |
| REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING | REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING | REACTOME_INTERLEUKIN_12_FAMILY_SIGNALING | 10/1438 | 57/23056 | 0.1754386 | 2.812874 | 3.534311 | 0.0025330 | 0.0121201 | 0.0077916 | SOD2/CA1/LCP1/ANXA2/SERPINB2/CNN2/EBI3/IL27RA/IL12RB1/MSN | 10 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_SECRETION | 17/1438 | 128/23056 | 0.1328125 | 2.129433 | 3.304736 | 0.0025401 | 0.0121459 | 0.0078082 | C1QTNF12/TGFB2/IL1A/PPARG/VEGFC/F2RL1/PCSK1/BMP6/ADAM9/ADCY8/ANKRD1/TCF7L2/IGF1/GIP/MYOM1/TGFB1/KCNN4 | 17 |
| HP_BRONCHIECTASIS | HP_BRONCHIECTASIS | HP_BRONCHIECTASIS | 17/1438 | 128/23056 | 0.1328125 | 2.129433 | 3.304736 | 0.0025401 | 0.0121459 | 0.0078082 | FCGR2A/CFAP221/SLC34A2/DNAH5/MCIDAS/CCNO/DSP/TAPBP/NFKB2/SCNN1A/NCKAP1L/IRF9/IL21R/LAT/TGFB1/RIN2/RAC2 | 17 |
| PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_DN | 40/1438 | 403/23056 | 0.0992556 | 1.591403 | 3.089065 | 0.0025566 | 0.0122203 | 0.0078560 | GBP3/PTPN22/S100A10/PRRX1/CAPG/SP110/MLPH/THRB/WWTR1/FGF5/ABCG2/PLK2/HAPLN1/ADTRP/CPA5/TRIM55/APBB1IP/ALOX5/ACSL5/IFITM2/IFITM3/SYT12/SERPINH1/MMP1/ROBO4/KRT4/EPYC/SLC10A2/TNFSF13B/NID2/LHX1/COLEC12/KLF2/SDCBP2/SAT1/CHST7/ITM2A/SAGE1/SPANXA2/MAGEA10 | 40 |
| HP_INTESTINAL_MALROTATION | HP_INTESTINAL_MALROTATION | HP_INTESTINAL_MALROTATION | 18/1438 | 139/23056 | 0.1294964 | 2.076265 | 3.282479 | 0.0025598 | 0.0122277 | 0.0078608 | LMOD1/ACTG2/CFAP221/MYLK/FGFRL1/DNAH5/MCIDAS/CCNO/RREB1/TFAP2A/ZFPM2/FGFR2/MYRF/HMGA2/SIX1/FOXF1/GATA6/GPC4 | 18 |
| GOBP_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | 9/1438 | 48/23056 | 0.1875000 | 3.006259 | 3.588578 | 0.0025617 | 0.0122277 | 0.0078608 | AGT/FN1/WNT5A/EREG/PDGFC/PDGFA/AQP1/IGF1/PDGFB | 9 |
| WOOD_EBV_EBNA1_TARGETS_DN | WOOD_EBV_EBNA1_TARGETS_DN | WOOD_EBV_EBNA1_TARGETS_DN | 9/1438 | 48/23056 | 0.1875000 | 3.006259 | 3.588578 | 0.0025617 | 0.0122277 | 0.0078608 | PTGS2/MYLK/TGFBI/PSMB8/GPNMB/MEST/TPM1/ADAP2/IL13RA1 | 9 |
| WP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873 | WP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873 | WP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873 | 9/1438 | 48/23056 | 0.1875000 | 3.006259 | 3.588578 | 0.0025617 | 0.0122277 | 0.0078608 | IL1B/HES1/AHRR/CAP2/AHR/MYOF/NQO1/SERPINB2/TGFB1 | 9 |
| LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | 38/1438 | 378/23056 | 0.1005291 | 1.611821 | 3.093302 | 0.0025913 | 0.0123650 | 0.0079490 | CCN1/SH2D2A/GPA33/PRRX1/RASSF5/CAPG/COL5A2/NRP2/MYLK/AMOTL2/CXCL1/PLAC8/RAI14/DAB2/ADAM19/LAMA4/PDGFRL/LOXL2/ZNF703/IDO1/PAPPA/NFKB2/BIRC3/NFE2/NID2/IL32/NUPR1/SLFN11/ACSF2/TNFRSF11A/BLVRB/NECTIN2/THBD/MYL9/COL18A1/HMOX1/LGALS2/LGALS1 | 38 |
| GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION | GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION | GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION | 15/1438 | 107/23056 | 0.1401869 | 2.247670 | 3.336292 | 0.0026181 | 0.0124813 | 0.0080238 | CTSS/MR1/ERAP2/HFE/HLA-E/HLA-C/PSMB8/TAPBP/EXT1/THBS1/CD68/CCR7/CLEC4M/ICAM1/RELB | 15 |
| GOBP_REGULATION_OF_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 15/1438 | 107/23056 | 0.1401869 | 2.247670 | 3.336292 | 0.0026181 | 0.0124813 | 0.0080238 | GFI1/PTPN22/RAB7B/DDX60/TLR3/F2RL1/TNFAIP3/CD36/CAV1/NLRP6/SLC15A3/BIRC3/OASL/DHX58/IFI35 | 15 |
| GOBP_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | GOBP_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | GOBP_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 26/1438 | 231/23056 | 0.1125541 | 1.804623 | 3.169912 | 0.0026185 | 0.0124813 | 0.0080238 | ZC3H12A/CCN1/AGT/TGFBR2/SOD3/F2RL1/TFAP2A/EDN1/CCN2/SOD2/CD36/PON3/PDK4/AKR1C3/ALOX5/SFTPD/HBD/MMP3/CRYAB/FOXO1/FBLN5/THBS1/NQO1/TGFB1/RAC2/PDGFB | 26 |
| CHYLA_CBFA2T3_TARGETS_DN | CHYLA_CBFA2T3_TARGETS_DN | CHYLA_CBFA2T3_TARGETS_DN | 27/1438 | 243/23056 | 0.1111111 | 1.781487 | 3.158550 | 0.0026338 | 0.0125459 | 0.0080653 | C1QTNF12/TINAGL1/TRIM17/MGLL/ELL2/SH3TC2/SLC22A23/RHAG/SH2D4A/ZNF703/LY6K/COL5A1/AIFM2/PHLDA2/CD82/OASL/SLC46A3/SLC7A7/MMP14/ZFP36L1/EPB42/MYLK3/NQO1/CNN1/BLVRB/BCAM/GPC4 | 27 |
| DOANE_RESPONSE_TO_ANDROGEN_DN | DOANE_RESPONSE_TO_ANDROGEN_DN | DOANE_RESPONSE_TO_ANDROGEN_DN | 27/1438 | 243/23056 | 0.1111111 | 1.781487 | 3.158550 | 0.0026338 | 0.0125459 | 0.0080653 | DHRS3/TINAGL1/CRABP2/PTPN14/LTBP1/CYBRD1/EPHA4/SP110/TDO2/GASK1B/RAI14/ABLIM3/DSP/EDN1/PSMB8/PTP4A1/SEMA3C/ASPH/IFITM3/PHLDA2/SERPINH1/EPS8/AMIGO2/THBS1/SMAD6/RRAS/MN1 | 27 |
| HP_HYPERLORDOSIS | HP_HYPERLORDOSIS | HP_HYPERLORDOSIS | 23/1438 | 196/23056 | 0.1173469 | 1.881468 | 3.196324 | 0.0026492 | 0.0126146 | 0.0081095 | HSPG2/FUCA1/FN1/COL6A3/FGFR3/TFAP2A/COL12A1/LAMA2/TMEM270/CSGALNACT1/TRPS1/COLEC10/TPM2/MYPN/FGFR2/ITGA7/FBN1/CAVIN1/SGCA/PIEZO2/TGFB1/COL6A2/BGN | 23 |
| MIKKELSEN_MEF_ICP_WITH_H3K27ME3 | MIKKELSEN_MEF_ICP_WITH_H3K27ME3 | MIKKELSEN_MEF_ICP_WITH_H3K27ME3 | 24/1438 | 208/23056 | 0.1153846 | 1.850005 | 3.176022 | 0.0027100 | 0.0128985 | 0.0082920 | HJV/KCNN3/BRINP3/NR5A2/EGF/GALNTL6/ADAMTS16/HLA-E/TMEM184A/PDE1C/PNOC/CA3/ERICH5/NPY4R/DKK1/PAMR1/NFE2/SLFN5/GRB7/HOXB3/HOXB13/TTLL6/ABCC3/NCCRP1 | 24 |
| GOBP_LYMPHOCYTE_MIGRATION | GOBP_LYMPHOCYTE_MIGRATION | GOBP_LYMPHOCYTE_MIGRATION | 16/1438 | 118/23056 | 0.1355932 | 2.174018 | 3.297555 | 0.0027116 | 0.0128985 | 0.0082920 | S1PR1/ECM1/ITGA4/WNT5A/ADTRP/CCL26/EXT1/SAA1/KLRC4-KLRK1/CCL5/CCR7/TNFSF14/ICAM1/IL27RA/XG/MSN | 16 |
| HP_EMG_MYOPATHIC_ABNORMALITIES | HP_EMG_MYOPATHIC_ABNORMALITIES | HP_EMG_MYOPATHIC_ABNORMALITIES | 16/1438 | 118/23056 | 0.1355932 | 2.174018 | 3.297555 | 0.0027116 | 0.0128985 | 0.0082920 | AGRN/CASQ1/DES/COL6A3/DOK7/COL12A1/SHH/TPM2/GAS1/MYPN/COL13A1/BAG3/CRYAB/ZIC2/SGCA/COL6A2 | 16 |
| GOBP_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | GOBP_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | 11/1438 | 67/23056 | 0.1641791 | 2.632346 | 3.450991 | 0.0027222 | 0.0129311 | 0.0083129 | ITGA4/KDR/SEMA5A/TNFAIP3/SERPINE1/ANGPT1/TEK/AKR1C3/THBS1/ICAM1/IL11 | 11 |
| GOBP_NECROTIC_CELL_DEATH | GOBP_NECROTIC_CELL_DEATH | GOBP_NECROTIC_CELL_DEATH | 11/1438 | 67/23056 | 0.1641791 | 2.632346 | 3.450991 | 0.0027222 | 0.0129311 | 0.0083129 | CASP8/TLR3/CAV1/FAS/NLRP6/BIRC3/SLC6A13/YBX3/PYGL/NUPR1/MLKL | 11 |
| GOBP_T_CELL_MIGRATION | GOBP_T_CELL_MIGRATION | GOBP_T_CELL_MIGRATION | 11/1438 | 67/23056 | 0.1641791 | 2.632346 | 3.450991 | 0.0027222 | 0.0129311 | 0.0083129 | S1PR1/ECM1/ITGA4/WNT5A/CCL26/CCL5/TNFSF14/ICAM1/IL27RA/XG/MSN | 11 |
| MARSON_FOXP3_TARGETS_UP | MARSON_FOXP3_TARGETS_UP | MARSON_FOXP3_TARGETS_UP | 11/1438 | 67/23056 | 0.1641791 | 2.632346 | 3.450991 | 0.0027222 | 0.0129311 | 0.0083129 | TNFRSF4/PDZK1IP1/ECM1/S100A10/CAPG/PSMB8/PDLIM2/CD44/CRIP1/MYH9/RAC2 | 11 |
| GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION | 14/1438 | 97/23056 | 0.1443299 | 2.314096 | 3.344959 | 0.0027255 | 0.0129332 | 0.0083143 | RAB7B/IL1A/IL1B/WNT5A/IL1RAP/SPON2/EREG/TLR3/F2RL1/TSLP/IL6/CD36/DDX58/MBP | 14 |
| GOBP_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | GOBP_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | GOBP_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | 14/1438 | 97/23056 | 0.1443299 | 2.314096 | 3.344959 | 0.0027255 | 0.0129332 | 0.0083143 | TGFB2/DLX1/DLX2/BCL6/HES1/TCIM/NOTCH1/YAP1/POSTN/MMP14/NFKBIA/LLGL2/GATA5/MAGEA1 | 14 |
| HP_ABNORMAL_CIRCULATING_ALBUMIN_CONCENTRATION | HP_ABNORMAL_CIRCULATING_ALBUMIN_CONCENTRATION | HP_ABNORMAL_CIRCULATING_ALBUMIN_CONCENTRATION | 14/1438 | 97/23056 | 0.1443299 | 2.314096 | 3.344959 | 0.0027255 | 0.0129332 | 0.0083143 | FN1/COL7A1/SLCO2A1/ARHGAP24/STX11/TNFSF15/CRB2/WT1/MYO1E/ITGA3/PLVAP/IL12RB1/APOL1/TBC1D8B | 14 |
| GOBP_REGULATION_OF_CELL_SHAPE | GOBP_REGULATION_OF_CELL_SHAPE | GOBP_REGULATION_OF_CELL_SHAPE | 19/1438 | 151/23056 | 0.1258278 | 2.017445 | 3.235106 | 0.0027509 | 0.0130400 | 0.0083830 | FBLIM1/RHOC/FN1/KDR/MYO10/ARHGAP18/ANXA1/DNMBP/EPS8/RND1/ITGA7/EPB42/TPM1/FMNL1/CDC42EP5/MYH9/RAC2/CDC42EP1/MSN | 19 |
| LANDIS_ERBB2_BREAST_TUMORS_324_UP | LANDIS_ERBB2_BREAST_TUMORS_324_UP | LANDIS_ERBB2_BREAST_TUMORS_324_UP | 19/1438 | 151/23056 | 0.1258278 | 2.017445 | 3.235106 | 0.0027509 | 0.0130400 | 0.0083830 | ERRFI1/FRRS1/TGFA/GALNT3/CXCL2/NPNT/ELL2/IER3/CRYBG1/TPD52L1/PERP/ARHGEF5/EHF/CD82/KRT8/CLDN7/DSG2/KCNN4/TFAP2C | 19 |
| SMID_BREAST_CANCER_ERBB2_UP | SMID_BREAST_CANCER_ERBB2_UP | SMID_BREAST_CANCER_ERBB2_UP | 19/1438 | 151/23056 | 0.1258278 | 2.017445 | 3.235106 | 0.0027509 | 0.0130400 | 0.0083830 | PADI3/BRINP3/KYNU/ITGB6/ELL2/CRYBG1/LAMA4/AKR1B10/ASPH/AQP3/CLIC3/PAPSS2/SCNN1A/EPYC/NQO1/GRB7/ABCC3/GGT1/IL13RA1 | 19 |
| HP_RETROGNATHIA | HP_RETROGNATHIA | HP_RETROGNATHIA | 30/1438 | 280/23056 | 0.1071429 | 1.717862 | 3.116991 | 0.0027547 | 0.0130539 | 0.0083919 | AGRN/TGFB2/COL3A1/RARB/TGFBR2/WNT5A/MYLK/ADAMTS3/FAT4/SEMA5A/ADAMTS2/EDN1/SIM1/FAM20C/GLI3/CSGALNACT1/ASPH/RSPO2/TPM2/ITGA8/COL13A1/BMP4/SIX1/FBN1/GLDN/FOXF1/COL1A1/PIEZO2/SIX5/FRMPD4 | 30 |
| REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING | REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING | REACTOME_INTERLEUKIN_1_FAMILY_SIGNALING | 18/1438 | 140/23056 | 0.1285714 | 2.061434 | 3.248943 | 0.0027704 | 0.0131238 | 0.0084368 | PTPN7/PTPN14/IL1R1/IL1A/IL1B/IL36G/IRAK2/IL1RAP/PSMB8/PSMB9/GSDMD/MAP3K8/ALOX5/NFKB2/SAA1/CASP1/NFKBIA/PSMB10 | 18 |
| GOMF_DNA_BINDING_TRANSCRIPTION_FACTOR_BINDING | GOMF_DNA_BINDING_TRANSCRIPTION_FACTOR_BINDING | GOMF_DNA_BINDING_TRANSCRIPTION_FACTOR_BINDING | 45/1438 | 469/23056 | 0.0959488 | 1.538384 | 3.038110 | 0.0027733 | 0.0131326 | 0.0084425 | PRRX1/CD34/NLRP3/BHLHE40/PPARG/FOXL2/BCL6/HES1/LEF1/ZNF366/STING1/FOXC1/ID4/RUNX2/CITED2/AHR/HOXA7/TRIP6/MDFIC/ZNF703/ZFPM2/PARP10/KLF4/NEK6/ANKRD1/HHEX/TCF7L2/YAP1/BHLHE41/HMGA2/GRIP1/OASL/FLT3/NFKBIA/DACT1/FOS/ESRRB/SOX8/MYOCD/WIPI1/SOX9/GATA6/BCL3/CEBPB/GAS2L1 | 45 |
| HP_ANORECTAL_ANOMALY | HP_ANORECTAL_ANOMALY | HP_ANORECTAL_ANOMALY | 33/1438 | 317/23056 | 0.1041009 | 1.669090 | 3.093732 | 0.0027784 | 0.0131525 | 0.0084553 | MMP23B/HSPG2/FCGR2A/COL5A2/TWIST2/TGFBR2/COL7A1/CD96/FAT4/FOXC1/RREB1/GLI3/TMEM270/SHH/GDF6/RSPO2/GAS1/COL5A1/NFKB2/FGFR2/MMP1/GRIP1/FREM2/ZIC2/DACT1/SALL1/FOXF1/MEOX1/COL1A1/ELANE/TGFB1/RAC2/MID1 | 33 |
| GOBP_MUSCLE_CELL_APOPTOTIC_PROCESS | GOBP_MUSCLE_CELL_APOPTOTIC_PROCESS | GOBP_MUSCLE_CELL_APOPTOTIC_PROCESS | 13/1438 | 87/23056 | 0.1494253 | 2.395792 | 3.364059 | 0.0027921 | 0.0132038 | 0.0084883 | ZC3H12A/AGT/PPARG/EDN1/SOD2/BAG3/IGF1/LTK/NUPR1/MYOCD/GATA6/LYPD3/HMOX1 | 13 |
| HP_ABNORMAL_GASTROINTESTINAL_MOTILITY | HP_ABNORMAL_GASTROINTESTINAL_MOTILITY | HP_ABNORMAL_GASTROINTESTINAL_MOTILITY | 13/1438 | 87/23056 | 0.1494253 | 2.395792 | 3.364059 | 0.0027921 | 0.0132038 | 0.0084883 | FCGR2A/LMOD1/ACTG2/MYLK/SAMD9/WT1/HMGA2/CAVIN1/CACNA1A/TGFB1/MYL9/COL4A6/COL4A5 | 13 |
| KEGG_APOPTOSIS | KEGG_APOPTOSIS | KEGG_APOPTOSIS | 13/1438 | 87/23056 | 0.1494253 | 2.395792 | 3.364059 | 0.0027921 | 0.0132038 | 0.0084883 | IL1R1/IL1A/IL1B/CASP10/CASP8/IRAK2/IL1RAP/TNFRSF10C/TNFRSF10A/FAS/BIRC3/TNFRSF1A/NFKBIA | 13 |
| GOBP_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | 12/1438 | 77/23056 | 0.1558442 | 2.498709 | 3.397436 | 0.0027991 | 0.0132319 | 0.0085063 | PTPN22/IL1R1/IL1B/WNT5A/TXK/TLR3/F2RL1/KLRC4-KLRK1/EBI3/IL27RA/IL12RB1/BCL3 | 12 |
| HP_ABNORMALITY_OF_THE_SCROTUM | HP_ABNORMALITY_OF_THE_SCROTUM | HP_ABNORMALITY_OF_THE_SCROTUM | 21/1438 | 174/23056 | 0.1206897 | 1.935063 | 3.193176 | 0.0028356 | 0.0133999 | 0.0086144 | SRD5A2/TWIST2/FAT4/SIM1/GLI3/SAMD9/PLAG1/ZFPM2/COLEC10/FGFR2/WT1/ALX4/MYRF/HMGA2/GRIP1/FREM2/BMP4/DACT1/SALL1/LHX1/SOX9 | 21 |
| HP_ABNORMAL_AORTIC_VALVE_CUSP_MORPHOLOGY | HP_ABNORMAL_AORTIC_VALVE_CUSP_MORPHOLOGY | HP_ABNORMAL_AORTIC_VALVE_CUSP_MORPHOLOGY | 15/1438 | 108/23056 | 0.1388889 | 2.226858 | 3.296007 | 0.0028691 | 0.0135538 | 0.0087133 | TGFB2/TGFBR2/MYLK/TMEM270/NOTCH1/WT1/ROBO4/MMP14/FBN1/SMAD6/MMP2/FOXF1/MYOCD/GATA6/GATA5 | 15 |
| GOBP_ALPHA_BETA_T_CELL_PROLIFERATION | GOBP_ALPHA_BETA_T_CELL_PROLIFERATION | GOBP_ALPHA_BETA_T_CELL_PROLIFERATION | 8/1438 | 40/23056 | 0.2000000 | 3.206676 | 3.602532 | 0.0028776 | 0.0135656 | 0.0087209 | PTPN22/PTPRC/TGFBR2/IL15/DOCK2/HLA-E/CD274/EBI3 | 8 |
| GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT | GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT | GOBP_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT | 8/1438 | 40/23056 | 0.2000000 | 3.206676 | 3.602532 | 0.0028776 | 0.0135656 | 0.0087209 | TNNC1/DSP/CAV1/STC1/HCN4/JUP/KCNJ2/DSG2 | 8 |
| GOBP_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | GOBP_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | GOBP_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY | 8/1438 | 40/23056 | 0.2000000 | 3.206676 | 3.602532 | 0.0028776 | 0.0135656 | 0.0087209 | MR1/PTPRC/IL7R/HLA-E/KLRD1/NCKAP1L/IL12RB1/NECTIN2 | 8 |
| GOBP_RESPONSE_TO_TUMOR_CELL | GOBP_RESPONSE_TO_TUMOR_CELL | GOBP_RESPONSE_TO_TUMOR_CELL | 8/1438 | 40/23056 | 0.2000000 | 3.206676 | 3.602532 | 0.0028776 | 0.0135656 | 0.0087209 | MR1/MICA/AHR/CD274/KLF4/NOTCH1/NECTIN2/IL4I1 | 8 |
| HP_PERITONITIS | HP_PERITONITIS | HP_PERITONITIS | 8/1438 | 40/23056 | 0.2000000 | 3.206676 | 3.602532 | 0.0028776 | 0.0135656 | 0.0087209 | ARHGAP24/CRB2/WT1/TNFRSF1A/MYO1E/ELANE/APOL1/TBC1D8B | 8 |
| HP_PES_VALGUS | HP_PES_VALGUS | HP_PES_VALGUS | 8/1438 | 40/23056 | 0.2000000 | 3.206676 | 3.602532 | 0.0028776 | 0.0135656 | 0.0087209 | COL6A3/SH3TC2/COL12A1/TPM2/MYPN/FBN1/SCN1B/COL6A2 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_NEURON_DEATH | GOBP_NEGATIVE_REGULATION_OF_NEURON_DEATH | GOBP_NEGATIVE_REGULATION_OF_NEURON_DEATH | 24/1438 | 209/23056 | 0.1148325 | 1.841154 | 3.150563 | 0.0028853 | 0.0135972 | 0.0087412 | TNFRSF1B/CSF1/CD34/DLX1/SLC7A11/GDNF/SOD2/GPNMB/FZD1/PTPRZ1/FGF20/ANGPT1/NRP1/NFATC4/SIX1/SIX4/FOXB1/CSF3/IL27RA/MAG/AXL/APOE/CEBPB/HMOX1 | 24 |
| GOBP_MATERNAL_PROCESS_INVOLVED_IN_FEMALE_PREGNANCY | GOBP_MATERNAL_PROCESS_INVOLVED_IN_FEMALE_PREGNANCY | GOBP_MATERNAL_PROCESS_INVOLVED_IN_FEMALE_PREGNANCY | 10/1438 | 58/23056 | 0.1724138 | 2.764376 | 3.469879 | 0.0028929 | 0.0136192 | 0.0087553 | PTGS2/SPP1/CITED2/PTN/STC1/HMX3/PGR/ITGA3/LIF/NDP | 10 |
| GOBP_P38MAPK_CASCADE | GOBP_P38MAPK_CASCADE | GOBP_P38MAPK_CASCADE | 10/1438 | 58/23056 | 0.1724138 | 2.764376 | 3.469879 | 0.0028929 | 0.0136192 | 0.0087553 | ZC3H12A/PTPN22/IL1B/SASH1/GDF6/BMP4/ZFP36L1/GADD45B/ZFP36/BMP2 | 10 |
| GOBP_POSITIVE_REGULATION_OF_WOUND_HEALING | GOBP_POSITIVE_REGULATION_OF_WOUND_HEALING | GOBP_POSITIVE_REGULATION_OF_WOUND_HEALING | 10/1438 | 58/23056 | 0.1724138 | 2.764376 | 3.469879 | 0.0028929 | 0.0136192 | 0.0087553 | MYLK/CLDN1/HBEGF/RREB1/CD36/SERPINE1/CCN4/ANXA1/THBS1/THBD | 10 |
| GOBP_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | GOBP_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | GOBP_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | 25/1438 | 221/23056 | 0.1131222 | 1.813731 | 3.134950 | 0.0029246 | 0.0137637 | 0.0088482 | RHOC/CYP26B1/WNT5A/AMOTL2/HES1/DOCK2/CAP2/GJA1/UST/AQP1/SHH/TEK/GSN/CRB2/RND1/NCKAP1L/FOXF1/CCR7/ANKFN1/LLGL2/ALPK2/MYH9/RAC2/WNT7B/MSN | 25 |
| ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | 22/1438 | 186/23056 | 0.1182796 | 1.896421 | 3.165846 | 0.0029373 | 0.0138188 | 0.0088836 | DHRS3/GPA33/CD34/GYPC/KYNU/CD96/STK32B/ABCG2/INPP4B/GYPA/DDX60/NPR3/CRHBP/SPARC/MDFIC/CSGALNACT1/GSN/IFITM2/EPS8/BLVRB/MN1/ITM2A | 22 |
| HP_VASCULAR_DILATATION | HP_VASCULAR_DILATATION | HP_VASCULAR_DILATATION | 27/1438 | 245/23056 | 0.1102041 | 1.766944 | 3.112639 | 0.0029545 | 0.0138562 | 0.0089077 | MMP23B/HSPG2/PTPN22/TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/TENT5A/TMEM270/EPHB4/EXT1/TPM2/CRB2/COL5A1/NOTCH1/MYPN/EFEMP2/ROBO4/FBLN5/FBN1/SMAD6/CAVIN1/COL1A1/RIN2/GATA5/BGN | 27 |
| HP_GINGIVAL_OVERGROWTH | HP_GINGIVAL_OVERGROWTH | HP_GINGIVAL_OVERGROWTH | 16/1438 | 119/23056 | 0.1344538 | 2.155749 | 3.260039 | 0.0029558 | 0.0138562 | 0.0089077 | KCNN3/COL3A1/NABP1/WNT5A/CD96/ADAMTS3/FAT4/ADAMTS2/FAM20C/TMEM270/FGFR2/C1S/C1R/MMP14/MMP2/RIN2 | 16 |
| AZARE_STAT3_TARGETS | AZARE_STAT3_TARGETS | AZARE_STAT3_TARGETS | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | ITGB6/FN1/B4GALT1/MMP3/NNMT/THBS1 | 6 |
| GOBP_COCHLEA_MORPHOGENESIS | GOBP_COCHLEA_MORPHOGENESIS | GOBP_COCHLEA_MORPHOGENESIS | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | WNT5A/TBX18/HOXA1/CTHRC1/SIX1/SOX9 | 6 |
| GOBP_NEUROEPITHELIAL_CELL_DIFFERENTIATION | GOBP_NEUROEPITHELIAL_CELL_DIFFERENTIATION | GOBP_NEUROEPITHELIAL_CELL_DIFFERENTIATION | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | HES1/FAM20C/SERPINE1/DLX3/BMP2/CEBPB | 6 |
| GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING | GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING | GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_BINDING | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | HSPG2/LDLRAP1/DAB2/CLU/DKK1/APOE | 6 |
| GOMF_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING | GOMF_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING | GOMF_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | LTBP1/TGFBR2/CD109/CD36/LRRC32/THBS1 | 6 |
| HASLINGER_B_CLL_WITH_13Q14_DELETION | HASLINGER_B_CLL_WITH_13Q14_DELETION | HASLINGER_B_CLL_WITH_13Q14_DELETION | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | ITGB5/ID4/NT5E/TPM2/KLF4/ALOX5 | 6 |
| HP_ABNORMAL_MORPHOLOGY_OF_THE_CHOROIDAL_VASCULATURE | HP_ABNORMAL_MORPHOLOGY_OF_THE_CHOROIDAL_VASCULATURE | HP_ABNORMAL_MORPHOLOGY_OF_THE_CHOROIDAL_VASCULATURE | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | HMCN1/CFH/EFEMP1/CFI/FBLN5/APOE | 6 |
| HP_MYELOMENINGOCELE | HP_MYELOMENINGOCELE | HP_MYELOMENINGOCELE | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | BMPER/GLI3/ALX4/GRIP1/FREM2/DACT1 | 6 |
| HP_VASCULAR_TORTUOSITY | HP_VASCULAR_TORTUOSITY | HP_VASCULAR_TORTUOSITY | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | TGFB2/TGFBR2/NT5E/COL5A1/EFEMP2/FBLN5 | 6 |
| KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_UP | KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_UP | KORKOLA_EMBRYONIC_CARCINOMA_VS_SEMINOMA_UP | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | ERRFI1/ABCG2/GJA1/SCNN1A/KRT18/GPC4 | 6 |
| REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | RHOC/MET/RND1/RRAS/MYL9/MYH9 | 6 |
| VALK_AML_WITH_11Q23_REARRANGED | VALK_AML_WITH_11Q23_REARRANGED | VALK_AML_WITH_11Q23_REARRANGED | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | C1orf54/P2RY2/ITGA7/MSLN/CES1/CD70 | 6 |
| WP_ANGIOGENESIS | WP_ANGIOGENESIS | WP_ANGIOGENESIS | 6/1438 | 24/23056 | 0.2500000 | 4.008345 | 3.802959 | 0.0029604 | 0.0138562 | 0.0089077 | KDR/ANGPT1/TEK/FGFR2/FLT1/PDGFB | 6 |
| GOBP_MACROPHAGE_DIFFERENTIATION | GOBP_MACROPHAGE_DIFFERENTIATION | GOBP_MACROPHAGE_DIFFERENTIATION | 9/1438 | 49/23056 | 0.1836735 | 2.944907 | 3.514965 | 0.0029675 | 0.0138802 | 0.0089231 | CSF1/CASP8/IL15/IL31RA/CSF2/INHBA/BMP4/TGFB1/LIF | 9 |
| ZHANG_PROLIFERATING_VS_QUIESCENT | ZHANG_PROLIFERATING_VS_QUIESCENT | ZHANG_PROLIFERATING_VS_QUIESCENT | 9/1438 | 49/23056 | 0.1836735 | 2.944907 | 3.514965 | 0.0029675 | 0.0138802 | 0.0089231 | TIE1/ITGA6/CXCL8/CXCL2/CCN2/TEK/CASP4/ITGA5/AXL | 9 |
| GOBP_POSITIVE_REGULATION_OF_COLD_INDUCED_THERMOGENESIS | GOBP_POSITIVE_REGULATION_OF_COLD_INDUCED_THERMOGENESIS | GOBP_POSITIVE_REGULATION_OF_COLD_INDUCED_THERMOGENESIS | 14/1438 | 98/23056 | 0.1428571 | 2.290483 | 3.301813 | 0.0030014 | 0.0140338 | 0.0090219 | TRPM8/PLAC8/PDGFC/ADRB2/GJA1/CD36/CAV1/EBF2/FABP4/STAT6/DIO2/IL4R/TRPV2/CEBPB | 14 |
| GOBP_JNK_CASCADE | GOBP_JNK_CASCADE | GOBP_JNK_CASCADE | 21/1438 | 175/23056 | 0.1200000 | 1.924006 | 3.164538 | 0.0030378 | 0.0141989 | 0.0091280 | PTPN22/IL1A/IL1B/WNT5A/TLR3/F2RL1/SH3RF2/TPD52L1/CCN2/SEMA3A/MDFIC/TRAF1/TNFRSF19/DACT1/CCR7/GADD45B/CDC42EP5/SIRPA/BIRC7/WNT7B/ARHGEF6 | 21 |
| GOBP_POSITIVE_REGULATION_OF_P38MAPK_CASCADE | GOBP_POSITIVE_REGULATION_OF_P38MAPK_CASCADE | GOBP_POSITIVE_REGULATION_OF_P38MAPK_CASCADE | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | ZC3H12A/IL1B/SASH1/GDF6/BMP4/GADD45B/BMP2 | 7 |
| GOBP_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | IL1B/VEGFC/FGF18/MMRN2/HHEX/FZD4/ITGA5 | 7 |
| HP_ABNORMAL_INTRAOCULAR_PRESSURE | HP_ABNORMAL_INTRAOCULAR_PRESSURE | HP_ABNORMAL_INTRAOCULAR_PRESSURE | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | FN1/ASPH/TEK/PITX3/LTBP2/LOXL1/COL18A1 | 7 |
| HP_ABNORMALITY_OF_COMPLEMENT_SYSTEM | HP_ABNORMALITY_OF_COMPLEMENT_SYSTEM | HP_ABNORMALITY_OF_COMPLEMENT_SYSTEM | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | CFH/SPP1/CFI/C9/C1S/SLC7A7/C3 | 7 |
| NOJIMA_SFRP2_TARGETS_UP | NOJIMA_SFRP2_TARGETS_UP | NOJIMA_SFRP2_TARGETS_UP | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | TNFRSF9/CSF1/CCN2/TNFAIP3/CLU/BAG3/GADD45B | 7 |
| REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | EREG/BTC/HBEGF/SPARC/PGR/YAP1/APOE | 7 |
| SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | TGFA/IL1A/COL8A1/SAA1/MMP1/CSF3/IL11 | 7 |
| WP_MONOAMINE_TRANSPORT | WP_MONOAMINE_TRANSPORT | WP_MONOAMINE_TRANSPORT | 7/1438 | 32/23056 | 0.2187500 | 3.507302 | 3.660543 | 0.0030662 | 0.0142171 | 0.0091397 | AGT/IL1R1/IL1B/TDO2/TNFRSF11B/FBXO32/NECTIN2 | 7 |
| GOBP_GLYCEROLIPID_CATABOLIC_PROCESS | GOBP_GLYCEROLIPID_CATABOLIC_PROCESS | GOBP_GLYCEROLIPID_CATABOLIC_PROCESS | 11/1438 | 68/23056 | 0.1617647 | 2.593635 | 3.394274 | 0.0030683 | 0.0142171 | 0.0091397 | PLA2G4A/CPS1/MGLL/AADAC/PLA2G7/APOC3/APOA1/PLA2G4D/LIPG/PLA2G4C/PNPLA3 | 11 |
| GOBP_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | GOBP_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | GOBP_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | 11/1438 | 68/23056 | 0.1617647 | 2.593635 | 3.394274 | 0.0030683 | 0.0142171 | 0.0091397 | S100A10/EPHA3/PHLDB2/KDR/TEK/NRP1/VCL/PTPRJ/MMP14/THBS1/SDC4 | 11 |
| GOBP_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | GOBP_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | GOBP_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY | 11/1438 | 68/23056 | 0.1617647 | 2.593635 | 3.394274 | 0.0030683 | 0.0142171 | 0.0091397 | CCN1/AGT/FGFR3/TXK/ANXA1/ANXA8L1/ANXA8/FGFR2/FLT1/CCL5/C5AR1 | 11 |
| HP_CONVEX_NASAL_RIDGE | HP_CONVEX_NASAL_RIDGE | HP_CONVEX_NASAL_RIDGE | 11/1438 | 68/23056 | 0.1617647 | 2.593635 | 3.394274 | 0.0030683 | 0.0142171 | 0.0091397 | COL3A1/FGFRL1/FGFR3/RUNX2/TENT5A/CSGALNACT1/ASPH/FGFR2/EFEMP2/GRIP1/COL1A1 | 11 |
| HP_RADIAL_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | HP_RADIAL_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | HP_RADIAL_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | 11/1438 | 68/23056 | 0.1617647 | 2.593635 | 3.394274 | 0.0030683 | 0.0142171 | 0.0091397 | WNT5A/CD96/FGFR3/GLI3/SAMD9/FGFR2/IGF1/NOG/BMP2/COL9A3/BGN | 11 |
| ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM | 11/1438 | 68/23056 | 0.1617647 | 2.593635 | 3.394274 | 0.0030683 | 0.0142171 | 0.0091397 | VCAM1/FN1/ANXA3/SPP1/CLU/VCL/ACTC1/COL1A1/SDC4/COL18A1/BGN | 11 |
| HP_ABNORMALITY_OF_MALAR_BONES | HP_ABNORMALITY_OF_MALAR_BONES | HP_ABNORMALITY_OF_MALAR_BONES | 24/1438 | 210/23056 | 0.1142857 | 1.832386 | 3.125242 | 0.0030700 | 0.0142171 | 0.0091397 | HSPG2/ADAMTSL4/TGFBR2/WNT5A/FGFR3/FAT4/FOXC1/RREB1/TFAP2A/RUNX2/FAM20C/SHH/COL5A1/FGFR2/SERPINH1/BMP4/FBN1/MAF/COL1A1/KCNJ2/BMP2/COL9A3/NDP/BGN | 24 |
| GOBP_3_UTR_MEDIATED_MRNA_DESTABILIZATION | GOBP_3_UTR_MEDIATED_MRNA_DESTABILIZATION | GOBP_3_UTR_MEDIATED_MRNA_DESTABILIZATION | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | ZC3H12A/RBM24/ZC3H12D/ZFP36L1/ZFP36 | 5 |
| GOBP_ANATOMICAL_STRUCTURE_ARRANGEMENT | GOBP_ANATOMICAL_STRUCTURE_ARRANGEMENT | GOBP_ANATOMICAL_STRUCTURE_ARRANGEMENT | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | NRP2/TFAP2A/SEMA3A/NRP1/HOXB2 | 5 |
| GOBP_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS | GOBP_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS | GOBP_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | GLI3/SHH/FGFR2/RBPMS2/FOXF1 | 5 |
| GOBP_GANGLION_DEVELOPMENT | GOBP_GANGLION_DEVELOPMENT | GOBP_GANGLION_DEVELOPMENT | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | NRP2/SEMA3A/NRP1/SIX1/SIX4 | 5 |
| GOBP_INFLAMMATORY_RESPONSE_TO_WOUNDING | GOBP_INFLAMMATORY_RESPONSE_TO_WOUNDING | GOBP_INFLAMMATORY_RESPONSE_TO_WOUNDING | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | IL1A/PPARG/ALOX5/TGFB1/HMOX1 | 5 |
| GOBP_MACROPHAGE_CYTOKINE_PRODUCTION | GOBP_MACROPHAGE_CYTOKINE_PRODUCTION | GOBP_MACROPHAGE_CYTOKINE_PRODUCTION | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | TGFB2/WNT5A/SPON2/CD36/TGFB1 | 5 |
| GOBP_POST_EMBRYONIC_ANIMAL_ORGAN_DEVELOPMENT | GOBP_POST_EMBRYONIC_ANIMAL_ORGAN_DEVELOPMENT | GOBP_POST_EMBRYONIC_ANIMAL_ORGAN_DEVELOPMENT | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | EFEMP1/KDR/KLF4/FBN1/MYO1E | 5 |
| GOBP_PULMONARY_VALVE_MORPHOGENESIS | GOBP_PULMONARY_VALVE_MORPHOGENESIS | GOBP_PULMONARY_VALVE_MORPHOGENESIS | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | TGFB2/SLIT2/NOTCH1/BMP4/SMAD6 | 5 |
| GOBP_REGULATION_OF_KETONE_BIOSYNTHETIC_PROCESS | GOBP_REGULATION_OF_KETONE_BIOSYNTHETIC_PROCESS | GOBP_REGULATION_OF_KETONE_BIOSYNTHETIC_PROCESS | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | DAB2/BMP6/AKR1C3/ADM/BMP2 | 5 |
| GOBP_TERPENOID_BIOSYNTHETIC_PROCESS | GOBP_TERPENOID_BIOSYNTHETIC_PROCESS | GOBP_TERPENOID_BIOSYNTHETIC_PROCESS | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | RPE65/CRABP2/AKR1C3/ALDH1A2/ALDH1A3 | 5 |
| GOCC_INFLAMMASOME_COMPLEX | GOCC_INFLAMMASOME_COMPLEX | GOCC_INFLAMMASOME_COMPLEX | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | NLRP3/GSDMD/NLRP6/CASP4/CASP1 | 5 |
| GOMF_DNA_BINDING_BENDING | GOMF_DNA_BINDING_BENDING | GOMF_DNA_BINDING_BENDING | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | LEF1/FOXD1/FOXC1/HHEX/HMGA2 | 5 |
| GOMF_INTERLEUKIN_1_RECEPTOR_BINDING | GOMF_INTERLEUKIN_1_RECEPTOR_BINDING | GOMF_INTERLEUKIN_1_RECEPTOR_BINDING | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | IL1A/IL1B/IL36G/IL1RAP/TRIP6 | 5 |
| GOMF_MECHANOSENSITIVE_ION_CHANNEL_ACTIVITY | GOMF_MECHANOSENSITIVE_ION_CHANNEL_ACTIVITY | GOMF_MECHANOSENSITIVE_ION_CHANNEL_ACTIVITY | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | TMEM63A/TMC1/PIEZO1/TMC8/PIEZO2 | 5 |
| GOMF_PHOSPHOLIPASE_A1_ACTIVITY | GOMF_PHOSPHOLIPASE_A1_ACTIVITY | GOMF_PHOSPHOLIPASE_A1_ACTIVITY | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | PLAAT4/PLAAT3/PLA2G4D/LIPG/PLA2G4C | 5 |
| GOUYER_TATI_TARGETS_DN | GOUYER_TATI_TARGETS_DN | GOUYER_TATI_TARGETS_DN | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | FN1/LOXL4/TAGLN/CSPG4/A4GALT | 5 |
| HP_INTESTINAL_HYPOPLASIA | HP_INTESTINAL_HYPOPLASIA | HP_INTESTINAL_HYPOPLASIA | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | LMOD1/ACTG2/MYLK/DOK7/GATA6 | 5 |
| HP_PREMATURE_VENTRICULAR_CONTRACTION | HP_PREMATURE_VENTRICULAR_CONTRACTION | HP_PREMATURE_VENTRICULAR_CONTRACTION | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | DSP/TRDN/JUP/KCNJ2/DSG2 | 5 |
| HP_SPONDYLOLISTHESIS | HP_SPONDYLOLISTHESIS | HP_SPONDYLOLISTHESIS | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | TGFB2/TGFBR2/RUNX2/FBN1/BMP2 | 5 |
| KANG_AR_TARGETS_UP | KANG_AR_TARGETS_UP | KANG_AR_TARGETS_UP | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | TGFB2/PDGFA/COL5A1/FGFR2/MMP2 | 5 |
| REACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS | REACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS | REACTOME_IL_6_TYPE_CYTOKINE_RECEPTOR_LIGAND_INTERACTIONS | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | OSMR/IL31RA/CTF1/IL11/LIF | 5 |
| REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY | REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY | REACTOME_TNF_RECEPTOR_SUPERFAMILY_TNFSF_MEMBERS_MEDIATING_NON_CANONICAL_NF_KB_PATHWAY | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | BIRC3/TNFSF13B/TNFRSF12A/TNFRSF11A/TNFSF14 | 5 |
| WP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS | WP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS | WP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | VCAM1/LEF1/NOTCH1/TCF7L2/POSTN | 5 |
| WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING | WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING | WP_CANONICAL_AND_NONCANONICAL_TGFB_SIGNALING | 5/1438 | 17/23056 | 0.2941176 | 4.715700 | 3.952642 | 0.0030820 | 0.0142171 | 0.0091397 | TGFBR2/LOXL2/LOXL4/LOXL1/TGFB1 | 5 |
| WP_GPCRS_CLASS_A_RHODOPSINLIKE | WP_GPCRS_CLASS_A_RHODOPSINLIKE | WP_GPCRS_CLASS_A_RHODOPSINLIKE | 28/1438 | 258/23056 | 0.1085271 | 1.740057 | 3.083051 | 0.0031165 | 0.0143712 | 0.0092387 | HTR1D/GPR39/ACKR3/HRH1/ACKR2/CCR3/SUCNR1/F2RL1/ADRB2/HCRTR2/GPR37/OR2F1/GPR20/NPY4R/HTR7/CCKBR/OR2AG1/OR6A2/P2RY2/C3AR1/HCAR1/EDNRB/BDKRB1/CCR7/FPR1/ADRA1D/CYSLTR1/LPAR4 | 28 |
| DUAN_PRDM5_TARGETS | DUAN_PRDM5_TARGETS | DUAN_PRDM5_TARGETS | 12/1438 | 78/23056 | 0.1538462 | 2.466674 | 3.346409 | 0.0031243 | 0.0143975 | 0.0092556 | TINAGL1/S100A2/CLDN16/RUNX2/COL19A1/NOTCH1/ALX4/WNT10B/NLRC5/SOCS3/GADD45B/RUNX1 | 12 |
| HP_PREAXIAL_POLYDACTYLY | HP_PREAXIAL_POLYDACTYLY | HP_PREAXIAL_POLYDACTYLY | 12/1438 | 78/23056 | 0.1538462 | 2.466674 | 3.346409 | 0.0031243 | 0.0143975 | 0.0092556 | FGFRL1/FGFR3/TFAP2A/GJA1/GLI3/SHH/COLEC10/FGFR2/GLI1/BMP4/DACT1/SALL1 | 12 |
| HP_ABNORMALITY_OF_THE_ZYGOMATIC_BONE | HP_ABNORMALITY_OF_THE_ZYGOMATIC_BONE | HP_ABNORMALITY_OF_THE_ZYGOMATIC_BONE | 27/1438 | 246/23056 | 0.1097561 | 1.759761 | 3.089842 | 0.0031269 | 0.0144049 | 0.0092604 | HSPG2/ADAMTSL4/TWIST2/TGFBR2/WNT5A/FGFR3/FAT4/FOXC1/RREB1/TFAP2A/RUNX2/FAM20C/TMEM270/SHH/COL5A1/FGFR2/SERPINH1/ZIC2/BMP4/FBN1/MAF/COL1A1/KCNJ2/BMP2/COL9A3/NDP/BGN | 27 |
| GOBP_POLYSACCHARIDE_METABOLIC_PROCESS | GOBP_POLYSACCHARIDE_METABOLIC_PROCESS | GOBP_POLYSACCHARIDE_METABOLIC_PROCESS | 15/1438 | 109/23056 | 0.1376147 | 2.206428 | 3.256163 | 0.0031396 | 0.0144489 | 0.0092887 | EGF/PPP1R3G/CSGALNACT1/EXT1/HAS2/PPP1R3C/PHLDA2/PYGM/IGF1/PYGL/B3GNT3/TGFB1/HAS1/PDGFB/CHST7 | 15 |
| GOBP_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 15/1438 | 109/23056 | 0.1376147 | 2.206428 | 3.256163 | 0.0031396 | 0.0144489 | 0.0092887 | RNF220/LGR6/EGF/SEMA5A/RSPO3/CAV1/RSPO2/HHEX/FGFR2/YAP1/WNT10B/DACT1/JUP/COL1A1/TGFB1 | 15 |
| GOBP_STRESS_FIBER_ASSEMBLY | GOBP_STRESS_FIBER_ASSEMBLY | GOBP_STRESS_FIBER_ASSEMBLY | 15/1438 | 109/23056 | 0.1376147 | 2.206428 | 3.256163 | 0.0031396 | 0.0144489 | 0.0092887 | S1PR1/RHOC/S100A10/PHLDB2/ITGB5/CCN2/MET/ZYX/ARHGEF5/NRP1/SYNPO2L/APOA1/CGNL1/TPM1/SDC4 | 15 |
| GOCC_EARLY_ENDOSOME | GOCC_EARLY_ENDOSOME | GOCC_EARLY_ENDOSOME | 39/1438 | 395/23056 | 0.0987342 | 1.583043 | 3.014488 | 0.0031434 | 0.0144612 | 0.0092966 | LDLRAP1/VCAM1/MR1/EPHA4/DNER/ACKR3/ACKR2/EPHA3/MME/ZFYVE28/KDR/TLR3/F2RL1/ADRB2/SERPINB1/HFE/HLA-E/HLA-C/PTP4A1/TMEM184A/GPNMB/SAMD9L/CAV1/CD274/ANXA1/NRP1/DKK1/IFITM3/RAB38/APOC3/APOA1/TPCN1/EHD4/HAP1/LIPG/CD22/APOE/EHD2/MLC1 | 39 |
| GOBP_REGULATION_OF_ENDOCYTOSIS | GOBP_REGULATION_OF_ENDOCYTOSIS | GOBP_REGULATION_OF_ENDOCYTOSIS | 24/1438 | 211/23056 | 0.1137441 | 1.823702 | 3.100059 | 0.0032647 | 0.0150092 | 0.0096489 | LDLRAP1/WNT5A/EPHA3/EGF/DAB2/ITGA2/F2RL1/HFE/CD36/SERPINE1/CAV1/CLU/ANGPT1/DKK1/APOC3/NCKAP1L/PRKD1/EHD4/ANXA2/CDH13/C3/CD22/AXL/APOE | 24 |
| MANNE_COVID19_NONICU_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_NONICU_VS_HEALTHY_DONOR_PLATELETS_DN | MANNE_COVID19_NONICU_VS_HEALTHY_DONOR_PLATELETS_DN | 24/1438 | 211/23056 | 0.1137441 | 1.823702 | 3.100059 | 0.0032647 | 0.0150092 | 0.0096489 | TGFB2/WNT9A/CAVIN2/ACKR2/KDR/CXCL6/CXCL5/ANXA3/GASK1B/IL7R/TGFBI/CLIC5/UTRN/SCIN/ANGPT1/PDCD1LG2/PAPPA/PAPSS2/YAP1/CAVIN1/SERPINB8/APCDD1L/MAP3K7CL/LGALS2 | 24 |
| HP_CONSTIPATION | HP_CONSTIPATION | HP_CONSTIPATION | 39/1438 | 396/23056 | 0.0984848 | 1.579045 | 2.997673 | 0.0032830 | 0.0150885 | 0.0096999 | MMP23B/ECE1/HSPG2/LAMC2/LAMB3/ACTG2/COL5A2/DES/TGFBR2/COL7A1/MITF/CD96/GDNF/SNCAIP/RREB1/HFE/PSMB8/TENT5A/TMEM270/SEMA3C/SEMA3D/SLC26A4/PODXL/SHH/GAS1/COL5A1/BIRC3/MMP1/TNFRSF1A/SCNN1A/STAT6/EDNRB/ZIC2/DACT1/SALL1/CAVIN1/COL1A1/CACNA1A/PRNP | 39 |
| GOBP_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | GOBP_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | GOBP_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 32/1438 | 308/23056 | 0.1038961 | 1.665806 | 3.033930 | 0.0032865 | 0.0150996 | 0.0097070 | C1QTNF12/ZC3H12A/PTGS2/TGFB2/IL1A/IL1B/PPARG/VEGFC/F2RL1/PCSK1/ABLIM3/BMP6/MICALL2/GLI3/TCAF2/ARHGEF5/SHH/ADAM9/ADCY8/ANKRD1/TCF7L2/BAG3/IGF1/PRKD1/JUP/GIP/MYOM1/TGFB1/KCNN4/PRNP/RAC2/TENM1 | 32 |
| BARIS_THYROID_CANCER_DN | BARIS_THYROID_CANCER_DN | BARIS_THYROID_CANCER_DN | 10/1438 | 59/23056 | 0.1694915 | 2.717522 | 3.406803 | 0.0032925 | 0.0151066 | 0.0097115 | SP110/COL8A1/VCL/CD44/MMP2/GRB7/ABCC3/TGFB1/IL13RA1/BGN | 10 |
| BOYLAN_MULTIPLE_MYELOMA_C_DN | BOYLAN_MULTIPLE_MYELOMA_C_DN | BOYLAN_MULTIPLE_MYELOMA_C_DN | 10/1438 | 59/23056 | 0.1694915 | 2.717522 | 3.406803 | 0.0032925 | 0.0151066 | 0.0097115 | SPP1/SERPINB1/TNFRSF21/FZD6/MYOF/TRIM5/RAB20/KCNN4/APOE/SAT1 | 10 |
| GOMF_MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_MONOCARBOXYLIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 10/1438 | 59/23056 | 0.1694915 | 2.717522 | 3.406803 | 0.0032925 | 0.0151066 | 0.0097115 | ABCG2/CD36/SLC16A12/SLC5A12/SLCO2B1/SLC6A13/SLC10A2/ABCC3/SLC16A5/SLC16A3 | 10 |
| HP_ABNORMAL_NASOLACRIMAL_SYSTEM_MORPHOLOGY | HP_ABNORMAL_NASOLACRIMAL_SYSTEM_MORPHOLOGY | HP_ABNORMAL_NASOLACRIMAL_SYSTEM_MORPHOLOGY | 10/1438 | 59/23056 | 0.1694915 | 2.717522 | 3.406803 | 0.0032925 | 0.0151066 | 0.0097115 | COL3A1/FOXL2/FGFR3/TFAP2A/FGFR2/BIRC3/GRIP1/FREM2/SIX1/SIX5 | 10 |
| GOBP_CARDIAC_CONDUCTION | GOBP_CARDIAC_CONDUCTION | GOBP_CARDIAC_CONDUCTION | 14/1438 | 99/23056 | 0.1414141 | 2.267347 | 3.259190 | 0.0032998 | 0.0151249 | 0.0097233 | ATP2B4/AGT/KCNE4/DSP/TBX18/GJA1/TRDN/CAV1/KCNA5/HCN4/JUP/KCNJ2/DSG2/SCN1B | 14 |
| GOBP_FATTY_ACID_TRANSPORT | GOBP_FATTY_ACID_TRANSPORT | GOBP_FATTY_ACID_TRANSPORT | 14/1438 | 99/23056 | 0.1414141 | 2.267347 | 3.259190 | 0.0032998 | 0.0151249 | 0.0097233 | CRABP2/PLA2G4A/IL1A/IL1B/PPARG/EDN1/CD36/FABP4/ANXA1/ACSL5/SPX/THBS1/TNFRSF11A/APOE | 14 |
| WP_HIPPO_SIGNALING_REGULATION_PATHWAYS | WP_HIPPO_SIGNALING_REGULATION_PATHWAYS | WP_HIPPO_SIGNALING_REGULATION_PATHWAYS | 14/1438 | 99/23056 | 0.1414141 | 2.267347 | 3.259190 | 0.0032998 | 0.0151249 | 0.0097233 | EPHA2/FGFR3/KDR/LEF1/CDH9/MET/TEK/TCF7L2/FGFR2/LATS2/FLT3/FLT1/CDH13/CDH15 | 14 |
| GOBP_FOREBRAIN_NEURON_DIFFERENTIATION | GOBP_FOREBRAIN_NEURON_DIFFERENTIATION | GOBP_FOREBRAIN_NEURON_DIFFERENTIATION | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | DLX1/DLX2/NRP2/HES1/INHBA/SEMA3A/NRP1/FGFR2 | 8 |
| GOBP_REGULATION_OF_MACROPHAGE_MIGRATION | GOBP_REGULATION_OF_MACROPHAGE_MIGRATION | GOBP_REGULATION_OF_MACROPHAGE_MIGRATION | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | CSF1/RARRES2/C3AR1/MMP14/THBS1/CYP19A1/CCL5/C5AR1 | 8 |
| GOBP_RESPONSE_TO_DEXAMETHASONE | GOBP_RESPONSE_TO_DEXAMETHASONE | GOBP_RESPONSE_TO_DEXAMETHASONE | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | ERRFI1/CPS1/CLDN1/EDN1/AQP1/PLAT/FBXO32/FIBIN | 8 |
| HP_ORTHOSTATIC_HYPOTENSION | HP_ORTHOSTATIC_HYPOTENSION | HP_ORTHOSTATIC_HYPOTENSION | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | COL5A2/SIM1/CAV1/TNFSF15/GSN/COL5A1/COL1A1/IL12RB1 | 8 |
| LEE_AGING_MUSCLE_DN | LEE_AGING_MUSCLE_DN | LEE_AGING_MUSCLE_DN | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | TNFRSF4/S100A10/COL3A1/PSMB8/PLA2G7/ADAM28/MYH2/COL1A1 | 8 |
| LI_LUNG_CANCER | LI_LUNG_CANCER | LI_LUNG_CANCER | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | S100A2/CSF2/KRT8/KRT18/KRT19/KRT17/HAP1/LGALS1 | 8 |
| ONO_AML1_TARGETS_DN | ONO_AML1_TARGETS_DN | ONO_AML1_TARGETS_DN | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | TNFRSF18/RUNX3/RUNX2/CASP4/IL4R/CCL5/CCR7/SOCS3 | 8 |
| PID_AMB2_NEUTROPHILS_PATHWAY | PID_AMB2_NEUTROPHILS_PATHWAY | PID_AMB2_NEUTROPHILS_PATHWAY | 8/1438 | 41/23056 | 0.1951220 | 3.128464 | 3.518091 | 0.0033831 | 0.0154655 | 0.0099423 | CCN2/IL6/PLAT/PLAU/SELPLG/MMP2/MYH2/ICAM1 | 8 |
| HP_ABNORMAL_AORTIC_MORPHOLOGY | HP_ABNORMAL_AORTIC_MORPHOLOGY | HP_ABNORMAL_AORTIC_MORPHOLOGY | 38/1438 | 384/23056 | 0.0989583 | 1.586637 | 2.989813 | 0.0033893 | 0.0154889 | 0.0099573 | MMP23B/HSPG2/LDLRAP1/PTPN22/TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/SLC34A2/RREB1/TENT5A/GJA1/GLI3/TMEM270/SHH/TPM2/GAS1/COL5A1/NOTCH1/MYPN/FGFR2/WT1/EFEMP2/ROBO4/ZIC2/MMP14/FBLN5/FBN1/SMAD6/MMP2/FOXF1/COL1A1/GATA6/APOE/RIN2/GATA5/BGN | 38 |
| REACTOME_SENSORY_PERCEPTION | REACTOME_SENSORY_PERCEPTION | REACTOME_SENSORY_PERCEPTION | 30/1438 | 284/23056 | 0.1056338 | 1.693667 | 3.033638 | 0.0033986 | 0.0155261 | 0.0099812 | AGRN/TAS1R1/DHRS3/HSPG2/RPE65/XIRP2/ITPR3/CLIC5/AKR1B10/OR2F1/TMC1/GSN/AKR1C3/EPS8L2/OR2AT4/APOC3/APOA1/OR10G4/OR10G7/SCNN1A/EPS8/LRP10/KCNJ2/SCN1B/APOE/SDC4/MYH9/MSN/GUCY2F/GPC4 | 30 |
| SWEET_KRAS_ONCOGENIC_SIGNATURE | SWEET_KRAS_ONCOGENIC_SIGNATURE | SWEET_KRAS_ONCOGENIC_SIGNATURE | 13/1438 | 89/23056 | 0.1460674 | 2.341954 | 3.271409 | 0.0034202 | 0.0155833 | 0.0100180 | CTSS/FCGR2A/CSF2/TGFBI/MDFI/CITED2/PHLDA2/KRT8/KRT18/PHLDA1/MT2A/CD68/SIRPA | 13 |
| WP_ALLOGRAFT_REJECTION | WP_ALLOGRAFT_REJECTION | WP_ALLOGRAFT_REJECTION | 13/1438 | 89/23056 | 0.1460674 | 2.341954 | 3.271409 | 0.0034202 | 0.0155833 | 0.0100180 | IL1A/IL1B/CASP8/CXCL8/GDNF/C9/HLA-E/HLA-C/MICA/COL5A1/FAS/C3/TGFB1 | 13 |
| JIANG_HYPOXIA_NORMAL | JIANG_HYPOXIA_NORMAL | JIANG_HYPOXIA_NORMAL | 23/1438 | 200/23056 | 0.1150000 | 1.843839 | 3.091210 | 0.0034217 | 0.0155833 | 0.0100180 | DPP4/PDGFC/NT5E/CITED2/SOD2/SERPINE1/CAV1/ASPH/NEK6/PPP1R3C/GPRC5A/RAB20/NFKBIA/CA12/NUPR1/PSMB10/ITGB4/GADD45B/ZFP36/BLVRB/SIRPA/TGM2/HMOX1 | 23 |
| GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION | 9/1438 | 50/23056 | 0.1800000 | 2.886008 | 3.443200 | 0.0034225 | 0.0155833 | 0.0100180 | OSR1/IL1A/HES1/HOXA7/CAV1/S1PR3/NOTCH1/YAP1/SOX9 | 9 |
| GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | 9/1438 | 50/23056 | 0.1800000 | 2.886008 | 3.443200 | 0.0034225 | 0.0155833 | 0.0100180 | ITPKB/BCL6/IL7R/IDO1/ST3GAL1/BMP4/CCL5/CCR7/AXL | 9 |
| GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION | 9/1438 | 50/23056 | 0.1800000 | 2.886008 | 3.443200 | 0.0034225 | 0.0155833 | 0.0100180 | RUNX3/ZC3H12A/NLRP3/BCL6/ANXA1/NCKAP1L/IL4R/IL12RB1/RUNX1 | 9 |
| GOBP_REGULATION_OF_GENE_SILENCING_BY_RNA | GOBP_REGULATION_OF_GENE_SILENCING_BY_RNA | GOBP_REGULATION_OF_GENE_SILENCING_BY_RNA | 9/1438 | 50/23056 | 0.1800000 | 2.886008 | 3.443200 | 0.0034225 | 0.0155833 | 0.0100180 | ZC3H12A/PPARG/IL6/AJUBA/BMP4/MYOCD/WTIP/ZFP36/TGFB1 | 9 |
| GOBP_T_CELL_APOPTOTIC_PROCESS | GOBP_T_CELL_APOPTOTIC_PROCESS | GOBP_T_CELL_APOPTOTIC_PROCESS | 9/1438 | 50/23056 | 0.1800000 | 2.886008 | 3.443200 | 0.0034225 | 0.0155833 | 0.0100180 | WNT5A/IL7R/GLI3/IDO1/ST3GAL1/CD274/FAS/BMP4/CCL5 | 9 |
| GOBP_T_CELL_MEDIATED_CYTOTOXICITY | GOBP_T_CELL_MEDIATED_CYTOTOXICITY | GOBP_T_CELL_MEDIATED_CYTOTOXICITY | 9/1438 | 50/23056 | 0.1800000 | 2.886008 | 3.443200 | 0.0034225 | 0.0155833 | 0.0100180 | MR1/PTPRC/IL7R/HLA-E/MICA/KLRD1/NCKAP1L/IL12RB1/NECTIN2 | 9 |
| KENNY_CTNNB1_TARGETS_UP | KENNY_CTNNB1_TARGETS_UP | KENNY_CTNNB1_TARGETS_UP | 9/1438 | 50/23056 | 0.1800000 | 2.886008 | 3.443200 | 0.0034225 | 0.0155833 | 0.0100180 | CCN1/PTPN22/NABP1/TM4SF1/SPP1/LOXL2/KRT7/TNFAIP2/MMP2 | 9 |
| BRUECKNER_TARGETS_OF_MIRLET7A3_UP | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | 15/1438 | 110/23056 | 0.1363636 | 2.186370 | 3.216750 | 0.0034308 | 0.0156108 | 0.0100356 | ERRFI1/PLA2G4A/ELF3/LAMB3/TFPI/FOXC1/RBM24/GJA1/PERP/LRATD2/GLIS3/KLF4/DKK1/CYP24A1/SAT1 | 15 |
| HP_VERTIGO | HP_VERTIGO | HP_VERTIGO | 15/1438 | 110/23056 | 0.1363636 | 2.186370 | 3.216750 | 0.0034308 | 0.0156108 | 0.0100356 | PTPN22/COL3A1/NABP1/TECRL/EGF/TRDN/SLC26A4/TPK1/DKK1/FAS/TNFRSF1A/JUP/CACNA1A/SCN1B/PDGFB | 15 |
| GOBP_REGULATION_OF_LIPID_KINASE_ACTIVITY | GOBP_REGULATION_OF_LIPID_KINASE_ACTIVITY | GOBP_REGULATION_OF_LIPID_KINASE_ACTIVITY | 11/1438 | 69/23056 | 0.1594203 | 2.556046 | 3.338567 | 0.0034489 | 0.0156775 | 0.0100785 | FGFR3/TEK/CCKBR/FLT3/FLT1/PRKD1/TNFAIP8L3/CCR7/SOCS3/TGFB1/PDGFB | 11 |
| LEE_CALORIE_RESTRICTION_NEOCORTEX_UP | LEE_CALORIE_RESTRICTION_NEOCORTEX_UP | LEE_CALORIE_RESTRICTION_NEOCORTEX_UP | 11/1438 | 69/23056 | 0.1594203 | 2.556046 | 3.338567 | 0.0034489 | 0.0156775 | 0.0100785 | EDN2/UBA7/TNNC1/PPIC/HLA-E/SERPINE1/PRKD1/NFKBIA/CES1/HOXB3/RELB | 11 |
| WP_RAC1PAK1P38MMP2_PATHWAY | WP_RAC1PAK1P38MMP2_PATHWAY | WP_RAC1PAK1P38MMP2_PATHWAY | 11/1438 | 69/23056 | 0.1594203 | 2.556046 | 3.338567 | 0.0034489 | 0.0156775 | 0.0100785 | TIE1/FN1/TNIP3/DOK2/ANGPT1/TEK/YAP1/FOXO1/NFKBIA/MMP2/GRB7 | 11 |
| HP_AMENORRHEA | HP_AMENORRHEA | HP_AMENORRHEA | 21/1438 | 177/23056 | 0.1186441 | 1.902265 | 3.107826 | 0.0034785 | 0.0156941 | 0.0100892 | HJV/CCDC141/PPARG/FOXL2/PCSK1/HFE/SIM1/SEMA3A/CAV1/ZFPM2/ITGA8/PAPSS2/WT1/FOS/CYP19A1/BNC1/CAVIN1/SOX9/AXL/BMP2/PDGFB | 21 |
| GOBP_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION | 12/1438 | 79/23056 | 0.1518987 | 2.435450 | 3.296167 | 0.0034794 | 0.0156941 | 0.0100892 | ERRFI1/ZC3H12A/PTPN22/CD34/TNFAIP3/GPNMB/CD274/IGF1/IL27RA/AXL/BCL3/SIRPA | 12 |
| AUJLA_IL22_AND_IL17A_SIGNALING | AUJLA_IL22_AND_IL17A_SIGNALING | AUJLA_IL22_AND_IL17A_SIGNALING | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | IL36G/CXCL1/CXCL5/CSF3 | 4 |
| BIOCARTA_MONOCYTE_PATHWAY | BIOCARTA_MONOCYTE_PATHWAY | BIOCARTA_MONOCYTE_PATHWAY | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | ITGA4/CD44/PECAM1/ICAM1 | 4 |
| FOURNIER_ACINAR_DEVELOPMENT_LATE_UP | FOURNIER_ACINAR_DEVELOPMENT_LATE_UP | FOURNIER_ACINAR_DEVELOPMENT_LATE_UP | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | GPNMB/BBOX1/CRYAB/APOE | 4 |
| GOBP_BRONCHUS_DEVELOPMENT | GOBP_BRONCHUS_DEVELOPMENT | GOBP_BRONCHUS_DEVELOPMENT | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | TGFBR2/BMP4/SOX9/WNT7B | 4 |
| GOBP_CELLULAR_RESPONSE_TO_UV_A | GOBP_CELLULAR_RESPONSE_TO_UV_A | GOBP_CELLULAR_RESPONSE_TO_UV_A | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | MME/MMP1/MMP3/MMP2 | 4 |
| GOBP_CRANIAL_NERVE_STRUCTURAL_ORGANIZATION | GOBP_CRANIAL_NERVE_STRUCTURAL_ORGANIZATION | GOBP_CRANIAL_NERVE_STRUCTURAL_ORGANIZATION | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | NRP2/SEMA3A/NRP1/HOXB2 | 4 |
| GOBP_DITERPENOID_BIOSYNTHETIC_PROCESS | GOBP_DITERPENOID_BIOSYNTHETIC_PROCESS | GOBP_DITERPENOID_BIOSYNTHETIC_PROCESS | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | CRABP2/AKR1C3/ALDH1A2/ALDH1A3 | 4 |
| GOBP_ENDOTHELIAL_CELL_MORPHOGENESIS | GOBP_ENDOTHELIAL_CELL_MORPHOGENESIS | GOBP_ENDOTHELIAL_CELL_MORPHOGENESIS | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | HEG1/MET/STC1/COL18A1 | 4 |
| GOBP_ISOPRENOID_CATABOLIC_PROCESS | GOBP_ISOPRENOID_CATABOLIC_PROCESS | GOBP_ISOPRENOID_CATABOLIC_PROCESS | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | CYP26B1/AKR1B10/AKR1C3/CYP26A1 | 4 |
| GOBP_LIMB_BUD_FORMATION | GOBP_LIMB_BUD_FORMATION | GOBP_LIMB_BUD_FORMATION | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | SEMA3C/SHH/FGFR2/SOX9 | 4 |
| GOBP_MEMBRANE_RAFT_ASSEMBLY | GOBP_MEMBRANE_RAFT_ASSEMBLY | GOBP_MEMBRANE_RAFT_ASSEMBLY | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | S100A10/CAV2/CAV1/ANXA2 | 4 |
| GOBP_REGULATION_OF_CELL_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_REGULATION_OF_CELL_CELL_ADHESION_MEDIATED_BY_INTEGRIN | GOBP_REGULATION_OF_CELL_CELL_ADHESION_MEDIATED_BY_INTEGRIN | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | DPP4/PODXL/PIEZO1/CCL5 | 4 |
| GOBP_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_T_HELPER_2_CELL_DIFFERENTIATION | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | NLRP3/BCL6/ANXA1/IL4R | 4 |
| GOBP_SINOATRIAL_NODE_DEVELOPMENT | GOBP_SINOATRIAL_NODE_DEVELOPMENT | GOBP_SINOATRIAL_NODE_DEVELOPMENT | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | TBX18/BMP4/HCN4/GATA6 | 4 |
| GOBP_TONIC_SMOOTH_MUSCLE_CONTRACTION | GOBP_TONIC_SMOOTH_MUSCLE_CONTRACTION | GOBP_TONIC_SMOOTH_MUSCLE_CONTRACTION | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | EDN2/AGT/MYLK/EDN1 | 4 |
| GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_DEVELOPMENT | GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_DEVELOPMENT | GOBP_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_DEVELOPMENT | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | HES1/NOTCH1/ADM/EFEMP2 | 4 |
| GOCC_INTERSTITIAL_MATRIX | GOCC_INTERSTITIAL_MATRIX | GOCC_INTERSTITIAL_MATRIX | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | ADAMTSL4/VIT/CCDC80/COL14A1 | 4 |
| GOCC_SERINE_TYPE_PEPTIDASE_COMPLEX | GOCC_SERINE_TYPE_PEPTIDASE_COMPLEX | GOCC_SERINE_TYPE_PEPTIDASE_COMPLEX | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | CFH/MBL2/PLAU/THBD | 4 |
| GOMF_STRUCTURAL_MOLECULE_ACTIVITY_CONFERRING_ELASTICITY | GOMF_STRUCTURAL_MOLECULE_ACTIVITY_CONFERRING_ELASTICITY | GOMF_STRUCTURAL_MOLECULE_ACTIVITY_CONFERRING_ELASTICITY | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | AHNAK/FBLN5/FBN1/EMILIN2 | 4 |
| HP_HUMERORADIAL_SYNOSTOSIS | HP_HUMERORADIAL_SYNOSTOSIS | HP_HUMERORADIAL_SYNOSTOSIS | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | TBX15/CYP26B1/FGFR2/NOG | 4 |
| HP_OVERGROWTH_OF_EXTERNAL_GENITALIA | HP_OVERGROWTH_OF_EXTERNAL_GENITALIA | HP_OVERGROWTH_OF_EXTERNAL_GENITALIA | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | PPARG/CAV1/FOS/CAVIN1 | 4 |
| HP_PORTAL_VEIN_THROMBOSIS | HP_PORTAL_VEIN_THROMBOSIS | HP_PORTAL_VEIN_THROMBOSIS | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | MET/NOTCH1/PIEZO1/KCNN4 | 4 |
| HP_RHEGMATOGENOUS_RETINAL_DETACHMENT | HP_RHEGMATOGENOUS_RETINAL_DETACHMENT | HP_RHEGMATOGENOUS_RETINAL_DETACHMENT | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | RPE65/TSPAN12/FZD4/NDP | 4 |
| HP_SOFT_DOUGHY_SKIN | HP_SOFT_DOUGHY_SKIN | HP_SOFT_DOUGHY_SKIN | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | COL5A2/ADAMTS2/COL5A1/COL1A1 | 4 |
| NIKOLSKY_BREAST_CANCER_7P15_AMPLICON | NIKOLSKY_BREAST_CANCER_7P15_AMPLICON | NIKOLSKY_BREAST_CANCER_7P15_AMPLICON | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | HOXA1/HOXA2/HOXA3/HOXA7 | 4 |
| REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY | REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY | REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | LAMC2/LAMB3/ITGA6/ITGB4 | 4 |
| TAGHAVI_NEOPLASTIC_TRANSFORMATION | TAGHAVI_NEOPLASTIC_TRANSFORMATION | TAGHAVI_NEOPLASTIC_TRANSFORMATION | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | AGRN/FLNC/NEK6/PDGFB | 4 |
| WHITESIDE_CISPLATIN_RESISTANCE_UP | WHITESIDE_CISPLATIN_RESISTANCE_UP | WHITESIDE_CISPLATIN_RESISTANCE_UP | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | ITGA7/ITGB4/GDF15/MX1 | 4 |
| YIH_RESPONSE_TO_ARSENITE_C5 | YIH_RESPONSE_TO_ARSENITE_C5 | YIH_RESPONSE_TO_ARSENITE_C5 | 4/1438 | 11/23056 | 0.3636364 | 5.830320 | 4.132740 | 0.0034880 | 0.0156941 | 0.0100892 | CRABP2/PLAU/KRT15/KRT19 | 4 |
| HP_APLASIA_HYPOPLASIA_OF_THE_PHALANGES_OF_THE_HAND | HP_APLASIA_HYPOPLASIA_OF_THE_PHALANGES_OF_THE_HAND | HP_APLASIA_HYPOPLASIA_OF_THE_PHALANGES_OF_THE_HAND | 26/1438 | 236/23056 | 0.1101695 | 1.766389 | 3.052122 | 0.0035050 | 0.0157658 | 0.0101353 | PTCH2/KCNN3/FN1/TGFBR2/WNT5A/FGFR3/ADAMTS2/RUNX2/GJA1/SHH/TRPS1/NOTCH1/FGFR2/GLI1/BMP4/FBN1/NOG/KCNJ2/SOX9/PIEZO2/BMP2/ARSL/FRMPD4/GPC4/ARHGEF6/BGN | 26 |
| RASHI_RESPONSE_TO_IONIZING_RADIATION_5 | RASHI_RESPONSE_TO_IONIZING_RADIATION_5 | RASHI_RESPONSE_TO_IONIZING_RADIATION_5 | 17/1438 | 132/23056 | 0.1287879 | 2.064905 | 3.164513 | 0.0035153 | 0.0158067 | 0.0101616 | CASP8/EPHA4/ESYT3/TDO2/F2RL1/TFAP2A/THBS2/INHBA/SERPINE1/COL14A1/PCSK5/NACC2/COL13A1/PPP1R3C/TMEM229B/LLGL2/DSG2 | 17 |
| GOBP_NEGATIVE_REGULATION_OF_BINDING | GOBP_NEGATIVE_REGULATION_OF_BINDING | GOBP_NEGATIVE_REGULATION_OF_BINDING | 20/1438 | 166/23056 | 0.1204819 | 1.931733 | 3.107253 | 0.0035938 | 0.0161545 | 0.0103852 | IFI16/ITGA4/SP100/XIRP1/LEF1/DAB2/ADRB2/HFE/MDFI/CAV1/DKK1/CARD16/HMGA2/NFATC4/NFKBIA/DACT1/NOG/TMC8/HMOX1/PDGFB | 20 |
| BROWNE_HCMV_INFECTION_12HR_DN | BROWNE_HCMV_INFECTION_12HR_DN | BROWNE_HCMV_INFECTION_12HR_DN | 14/1438 | 100/23056 | 0.1400000 | 2.244673 | 3.217077 | 0.0036219 | 0.0162702 | 0.0104596 | DHRS3/FGF5/DAB2/SERPINB1/PTP4A1/CRYBG1/THBS2/GLI3/SERPINE1/VWA5A/MYH8/RIN2/RUNX1/MID1 | 14 |
| GOBP_B_CELL_PROLIFERATION | GOBP_B_CELL_PROLIFERATION | GOBP_B_CELL_PROLIFERATION | 14/1438 | 100/23056 | 0.1400000 | 2.244673 | 3.217077 | 0.0036219 | 0.0162702 | 0.0104596 | TNFRSF4/PTPRC/BCL6/LEF1/IL7R/MZB1/TNFRSF21/AHR/IFNE/NCKAP1L/TNFSF13B/CD70/CD22/NFATC2 | 14 |
| HP_RENAL_HYPOPLASIA_APLASIA | HP_RENAL_HYPOPLASIA_APLASIA | HP_RENAL_HYPOPLASIA_APLASIA | 32/1438 | 310/23056 | 0.1032258 | 1.655058 | 2.994765 | 0.0036269 | 0.0162821 | 0.0104672 | KYNU/CCDC141/RARB/CD96/FGFR3/FAT4/RREB1/TFAP2A/TBX18/GLI3/TMEM270/SEMA3A/SHH/FGF20/GDF6/GAS1/ITGA8/FGFR2/GLI1/HMGA2/GRIP1/FREM2/ZIC2/BMP4/DACT1/SIX1/SALL1/LHX1/MEOX1/KCNJ2/PIEZO2/SIX5 | 32 |
| HP_TALIPES_EQUINOVARUS | HP_TALIPES_EQUINOVARUS | HP_TALIPES_EQUINOVARUS | 32/1438 | 310/23056 | 0.1032258 | 1.655058 | 2.994765 | 0.0036269 | 0.0162821 | 0.0104672 | HSPG2/TBX15/TGFB2/COL3A1/COL5A2/DES/COL6A3/TWIST2/TGFBR2/LAMB2/FGFRL1/FAT4/ARSI/RREB1/COL12A1/ADGRG6/BMPER/GLI3/SAMD9/RSPO2/TPM2/COL5A1/ITGA8/MYPN/ITGA7/SMAD6/MYH8/COL1A1/SOX9/PIEZO2/COL6A2/GPC4 | 32 |
| GOBP_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | GOBP_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | GOBP_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | 24/1438 | 213/23056 | 0.1126761 | 1.806578 | 3.050098 | 0.0036853 | 0.0164312 | 0.0105631 | AGRN/NRP2/EPHA4/WNT5A/IL1RAP/GRID2/SLC7A11/MDGA1/TPBG/THBS2/FZD1/DKK1/SRGN/AMIGO2/NFATC4/LRFN5/SIX1/SIX4/APOE/PRNP/FRMPD4/SRPX2/GPC4/SLITRK4 | 24 |
| APPEL_IMATINIB_RESPONSE | APPEL_IMATINIB_RESPONSE | APPEL_IMATINIB_RESPONSE | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | FUCA1/PPARG/PLD1/MSR1/CD68/APOE/C5AR1 | 7 |
| GOBP_MATERNAL_PLACENTA_DEVELOPMENT | GOBP_MATERNAL_PLACENTA_DEVELOPMENT | GOBP_MATERNAL_PLACENTA_DEVELOPMENT | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | PTGS2/SPP1/CITED2/PTN/STC1/LIF/NDP | 7 |
| GOBP_PROTEIN_CONTAINING_COMPLEX_REMODELING | GOBP_PROTEIN_CONTAINING_COMPLEX_REMODELING | GOBP_PROTEIN_CONTAINING_COMPLEX_REMODELING | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | AGT/PLA2G7/APOC3/APOA1/CETP/LIPG/APOE | 7 |
| GOBP_REGULATION_OF_FATTY_ACID_TRANSPORT | GOBP_REGULATION_OF_FATTY_ACID_TRANSPORT | GOBP_REGULATION_OF_FATTY_ACID_TRANSPORT | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | PLA2G4A/IL1A/IL1B/EDN1/ACSL5/THBS1/TNFRSF11A | 7 |
| GOBP_REGULATION_OF_RENAL_SYSTEM_PROCESS | GOBP_REGULATION_OF_RENAL_SYSTEM_PROCESS | GOBP_REGULATION_OF_RENAL_SYSTEM_PROCESS | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | AGT/F2RL1/EDN1/STC1/SPX/EDNRB/PDGFB | 7 |
| HP_HYPOPLASIA_OF_THE_IRIS | HP_HYPOPLASIA_OF_THE_IRIS | HP_HYPOPLASIA_OF_THE_IRIS | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | LAMB2/MITF/FGFRL1/FOXC1/WT1/FBN1/NDP | 7 |
| TANG_SENESCENCE_TP53_TARGETS_UP | TANG_SENESCENCE_TP53_TARGETS_UP | TANG_SENESCENCE_TP53_TARGETS_UP | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | SLC4A4/TSPAN12/MMP3/ABCA8/GMFG/ADAMTS5/SIM2 | 7 |
| VALK_AML_CLUSTER_10 | VALK_AML_CLUSTER_10 | VALK_AML_CLUSTER_10 | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | CRIM1/F2RL1/RBPMS/TPM2/C3AR1/CD22/MN1 | 7 |
| WP_WHITE_FAT_CELL_DIFFERENTIATION | WP_WHITE_FAT_CELL_DIFFERENTIATION | WP_WHITE_FAT_CELL_DIFFERENTIATION | 7/1438 | 33/23056 | 0.2121212 | 3.401020 | 3.559804 | 0.0036856 | 0.0164312 | 0.0105631 | PPARG/CEBPD/KLF4/WNT10B/FOXO1/KLF2/CEBPB | 7 |
| HP_THORACIC_AORTIC_ANEURYSM | HP_THORACIC_AORTIC_ANEURYSM | HP_THORACIC_AORTIC_ANEURYSM | 19/1438 | 155/23056 | 0.1225806 | 1.965382 | 3.110227 | 0.0036907 | 0.0164312 | 0.0105631 | MMP23B/HSPG2/TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/TENT5A/TMEM270/TPM2/COL5A1/NOTCH1/MYPN/ROBO4/FBLN5/FBN1/SMAD6/COL1A1/GATA5 | 19 |
| WP_MESODERMAL_COMMITMENT_PATHWAY | WP_MESODERMAL_COMMITMENT_PATHWAY | WP_MESODERMAL_COMMITMENT_PATHWAY | 19/1438 | 155/23056 | 0.1225806 | 1.965382 | 3.110227 | 0.0036907 | 0.0164312 | 0.0105631 | BHLHE40/RARB/LEF1/ADAM19/FOXC1/INHBA/EXT1/KLF4/FZD8/DKK1/TRIM5/FZD4/YAP1/HMGA2/ZIC2/BMP4/SMAD6/NOG/GATA6 | 19 |
| DELACROIX_RAR_TARGETS_DN | DELACROIX_RAR_TARGETS_DN | DELACROIX_RAR_TARGETS_DN | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | FSTL1/PLSCR2/TPM2/NRP1/FGFR2/EMP1 | 6 |
| GOBP_AMELOGENESIS | GOBP_AMELOGENESIS | GOBP_AMELOGENESIS | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | ITGB6/AMTN/ENAM/PERP/FAM20C/SLC24A4 | 6 |
| GOBP_IMMUNE_RESPONSE_TO_TUMOR_CELL | GOBP_IMMUNE_RESPONSE_TO_TUMOR_CELL | GOBP_IMMUNE_RESPONSE_TO_TUMOR_CELL | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | MR1/MICA/AHR/CD274/NECTIN2/IL4I1 | 6 |
| GOBP_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY | GOBP_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY | GOBP_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | NMI/SP100/PPARG/PARP14/TXK/NLRC5 | 6 |
| GOBP_POSITIVE_REGULATION_OF_FATTY_ACID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_FATTY_ACID_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_FATTY_ACID_TRANSPORT | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | PLA2G4A/IL1A/IL1B/EDN1/ACSL5/TNFRSF11A | 6 |
| GOBP_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | GOBP_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | GOBP_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | AGT/SUCNR1/F2RL1/PCSK5/EDNRB/PDGFB | 6 |
| GOBP_TRABECULA_FORMATION | GOBP_TRABECULA_FORMATION | GOBP_TRABECULA_FORMATION | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | BMP10/ADGRG6/TEK/WNT10B/MMP2/COL1A1 | 6 |
| GOCC_MYOFILAMENT | GOCC_MYOFILAMENT | GOCC_MYOFILAMENT | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | LMOD1/TNNC1/LMOD2/TPM2/TPM1/MYOM1 | 6 |
| GOMF_THREONINE_TYPE_PEPTIDASE_ACTIVITY | GOMF_THREONINE_TYPE_PEPTIDASE_ACTIVITY | GOMF_THREONINE_TYPE_PEPTIDASE_ACTIVITY | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | PSMB8/PSMB9/PSMB10/GGTLC3/GGTLC2/GGT1 | 6 |
| HP_TARSAL_SYNOSTOSIS | HP_TARSAL_SYNOSTOSIS | HP_TARSAL_SYNOSTOSIS | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | FGFR3/GLI3/GDF6/TPM2/FGFR2/NOG | 6 |
| LA_MEN1_TARGETS | LA_MEN1_TARGETS | LA_MEN1_TARGETS | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | FRRS1/CASP8/ADAM19/ITGA5/NUPR1/CNN1 | 6 |
| PID_LYMPH_ANGIOGENESIS_PATHWAY | PID_LYMPH_ANGIOGENESIS_PATHWAY | PID_LYMPH_ANGIOGENESIS_PATHWAY | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | ITGA4/FN1/VEGFC/ITGA2/ITGA5/COL1A1 | 6 |
| REACTOME_SIGNALING_BY_EGFR_IN_CANCER | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | TGFA/EPGN/EREG/BTC/EGF/HBEGF | 6 |
| WANG_BARRETTS_ESOPHAGUS_DN | WANG_BARRETTS_ESOPHAGUS_DN | WANG_BARRETTS_ESOPHAGUS_DN | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | FGFR3/SERPINB1/GPNMB/AQP3/JUP/KLK6 | 6 |
| WONG_ENDMETRIUM_CANCER_UP | WONG_ENDMETRIUM_CANCER_UP | WONG_ENDMETRIUM_CANCER_UP | 6/1438 | 25/23056 | 0.2400000 | 3.848011 | 3.674596 | 0.0036925 | 0.0164312 | 0.0105631 | S100A2/CXCL5/CDC20B/FOXC1/TFAP2A/EPPK1 | 6 |
| REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | 27/1438 | 249/23056 | 0.1084337 | 1.738559 | 3.022075 | 0.0036962 | 0.0164423 | 0.0105702 | SLC1A7/SLCO2A1/SLC34A2/SLC4A4/SLC7A11/SLC12A7/SLC6A7/RHAG/SLC22A1/SLC26A4/SLC26A7/SLC22A18/SLC5A12/SLC15A3/SLCO2B1/SLC6A13/SLC2A14/SLC38A4/SLC7A7/SLC24A4/SLC28A1/SLC47A1/SLC16A3/SLC14A2/SLC14A1/SLC7A10/RUNX1 | 27 |
| HP_ABNORMAL_DIAPHYSIS_MORPHOLOGY | HP_ABNORMAL_DIAPHYSIS_MORPHOLOGY | HP_ABNORMAL_DIAPHYSIS_MORPHOLOGY | 31/1438 | 298/23056 | 0.1040268 | 1.667902 | 2.993009 | 0.0036999 | 0.0164536 | 0.0105775 | HSPG2/FN1/SLCO2A1/FGFR3/NKX3-2/SGMS2/RUNX2/TENT5A/GJA1/FAM20C/GLI3/TMEM270/SHH/CSGALNACT1/RSPO2/TRPS1/EXT1/TNFRSF11B/TPM2/PAPSS2/FGFR2/SERPINH1/GLI1/FBN1/CYP19A1/COL1A1/SOX9/TNFRSF11A/TGFB1/COL9A3/BGN | 31 |
| HP_POLYHYDRAMNIOS | HP_POLYHYDRAMNIOS | HP_POLYHYDRAMNIOS | 26/1438 | 237/23056 | 0.1097046 | 1.758936 | 3.028903 | 0.0037098 | 0.0164923 | 0.0106023 | AGRN/HSPG2/PRRX1/LMOD1/ACTG2/ITGA6/CD96/MYLK/FGFR3/DOK7/ADAMTS3/RREB1/ADGRG6/RSPO2/TPM2/CRB2/MYPN/COL13A1/ITGA7/GLDN/FOXF1/PIEZO1/SOX9/ITGB4/PLVAP/GPC4 | 26 |
| GOBP_STRIATED_MUSCLE_CONTRACTION | GOBP_STRIATED_MUSCLE_CONTRACTION | GOBP_STRIATED_MUSCLE_CONTRACTION | 21/1438 | 178/23056 | 0.1179775 | 1.891579 | 3.079745 | 0.0037182 | 0.0165188 | 0.0106194 | ZC3H12A/CASQ1/BMP10/KCNE4/TNNC1/DSP/GJA1/CCN2/CAV1/STC1/GSN/KCNA5/TPM1/HCN4/MYH8/JUP/MYL4/KCNJ2/DSG2/SCN1B/SMPX | 21 |
| HP_ABNORMAL_PHARYNX_MORPHOLOGY | HP_ABNORMAL_PHARYNX_MORPHOLOGY | HP_ABNORMAL_PHARYNX_MORPHOLOGY | 21/1438 | 178/23056 | 0.1179775 | 1.891579 | 3.079745 | 0.0037182 | 0.0165188 | 0.0106194 | GFI1/PTPN22/COL5A2/CFI/DNAH5/IL7R/MCIDAS/PSMB8/TAPBP/GJA1/GLI3/SHH/COL5A1/NFKB2/FGFR2/TNFRSF1A/SCNN1A/IL21R/ELANE/RAC2/MID1 | 21 |
| BERNARD_PPAPDC1B_TARGETS_DN | BERNARD_PPAPDC1B_TARGETS_DN | BERNARD_PPAPDC1B_TARGETS_DN | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | SEL1L3/MACC1/STC1/ZNF703/FBXO32/PROSER2/FGFR2/SERPINA1/THBS1/MT1X | 10 |
| GOBP_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | GOBP_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | GOBP_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | DSP/TBX18/GJA1/TRDN/CAV1/KCNA5/HCN4/JUP/DSG2/SCN1B | 10 |
| GOBP_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | PTPN22/LAX1/AGT/IL1B/PPARG/CAV1/PTPRJ/BMP4/APOE/BMP2 | 10 |
| GOBP_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | ZC3H12A/PTGS2/IL1B/GLI3/SHH/TCF7L2/BAG3/PRKD1/JUP/TGFB1 | 10 |
| GOBP_REGULATION_OF_JUN_KINASE_ACTIVITY | GOBP_REGULATION_OF_JUN_KINASE_ACTIVITY | GOBP_REGULATION_OF_JUN_KINASE_ACTIVITY | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | PTPN22/EPHA4/WNT5A/EDN1/SASH1/ARHGEF5/FZD8/DKK1/FZD4/TNFRSF11A | 10 |
| HP_COXA_VARA | HP_COXA_VARA | HP_COXA_VARA | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | HSPG2/PRG4/FN1/WNT5A/NKX3-2/ADAMTS2/RUNX2/EXT1/COL1A1/COL9A3 | 10 |
| HP_STOMATITIS | HP_STOMATITIS | HP_STOMATITIS | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | GFI1/NLRP3/KYNU/NABP1/CASP10/IL17RC/IL6/FAS/IRF9/ELANE | 10 |
| KYNG_DNA_DAMAGE_BY_4NQO_OR_UV | KYNG_DNA_DAMAGE_BY_4NQO_OR_UV | KYNG_DNA_DAMAGE_BY_4NQO_OR_UV | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | PRELP/IL1R1/HNMT/PTPRK/TCF7L2/C3AR1/IGF1/KRT13/SERPINB2/RIN2 | 10 |
| VANASSE_BCL2_TARGETS_DN | VANASSE_BCL2_TARGETS_DN | VANASSE_BCL2_TARGETS_DN | 10/1438 | 60/23056 | 0.1666667 | 2.672230 | 3.345028 | 0.0037347 | 0.0165439 | 0.0106355 | PTPN22/IFI16/FN1/ACKR3/ACKR2/PLA2G7/TRPS1/TRAF1/COL5A1/MYL4 | 10 |
| HP_ABNORMAL_CARDIAC_VENTRICULAR_FUNCTION | HP_ABNORMAL_CARDIAC_VENTRICULAR_FUNCTION | HP_ABNORMAL_CARDIAC_VENTRICULAR_FUNCTION | 15/1438 | 111/23056 | 0.1351351 | 2.166673 | 3.177758 | 0.0037437 | 0.0165785 | 0.0106577 | LDLRAP1/TGFB2/TGFBR2/WNT5A/MYLK/SLC34A2/LAMA2/CITED2/FLNC/MYPN/EFEMP2/FBLN5/ACTC1/FBN1/GATA6 | 15 |
| GOBP_RESPONSE_TO_CALCIUM_ION | GOBP_RESPONSE_TO_CALCIUM_ION | GOBP_RESPONSE_TO_CALCIUM_ION | 18/1438 | 144/23056 | 0.1250000 | 2.004173 | 3.117542 | 0.0037628 | 0.0166470 | 0.0107018 | S100A16/ITPKB/WNT5A/SUCNR1/TRPC3/CRHBP/PCSK1/EDN1/ITPR3/CAV1/ADAM9/ADCY8/AQP3/AKR1C3/SYT12/ALOX5AP/FOS/THBS1 | 18 |
| HP_CARDIAC_CONDUCTION_ABNORMALITY | HP_CARDIAC_CONDUCTION_ABNORMALITY | HP_CARDIAC_CONDUCTION_ABNORMALITY | 18/1438 | 144/23056 | 0.1250000 | 2.004173 | 3.117542 | 0.0037628 | 0.0166470 | 0.0107018 | DES/TNNC1/MYOZ2/GJA1/TRDN/CITED2/SEMA3A/SCNN1A/MMP14/ACTC1/HCN4/MMP2/JUP/KCNJ2/GATA6/CACNA1A/SCN1B/GPC4 | 18 |
| HP_VERTEBRAL_SEGMENTATION_DEFECT | HP_VERTEBRAL_SEGMENTATION_DEFECT | HP_VERTEBRAL_SEGMENTATION_DEFECT | 18/1438 | 144/23056 | 0.1250000 | 2.004173 | 3.117542 | 0.0037628 | 0.0166470 | 0.0107018 | PTCH2/KYNU/FN1/WNT5A/FGFRL1/SH3TC2/BMPER/GLI3/TMEM270/GDF6/TPM2/DKK1/FGFR2/GRIP1/FREM2/MEOX1/NOG/GPC4 | 18 |
| GOBP_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE | GOBP_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE | GOBP_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE | 13/1438 | 90/23056 | 0.1444444 | 2.315933 | 3.226016 | 0.0037747 | 0.0166889 | 0.0107287 | EDN1/TNFAIP3/IL6/AQP1/MET/GPR37/TRPA1/ANXA1/STAT6/NQO1/KLF2/AXL/SIRPA | 13 |
| WP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA | WP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA | WP_NCRNAS_INVOLVED_IN_WNT_SIGNALING_IN_HEPATOCELLULAR_CARCINOMA | 13/1438 | 90/23056 | 0.1444444 | 2.315933 | 3.226016 | 0.0037747 | 0.0166889 | 0.0107287 | WNT5A/LEF1/NKD2/FZD1/FZD6/KLF4/FZD8/DKK1/PLAU/TCF7L2/FOSL1/WNT10B/WNT7B | 13 |
| FIGUEROA_AML_METHYLATION_CLUSTER_1_UP | FIGUEROA_AML_METHYLATION_CLUSTER_1_UP | FIGUEROA_AML_METHYLATION_CLUSTER_1_UP | 16/1438 | 122/23056 | 0.1311475 | 2.102738 | 3.149682 | 0.0037995 | 0.0167879 | 0.0107923 | TIE1/CAVIN2/FSTL1/CXCL1/EREG/CRHBP/ADGRG6/TEK/JCAD/WT1/VWA5A/VWF/YBX3/MSRB3/PAQR5/MYL4 | 16 |
| GOBP_AMINE_METABOLIC_PROCESS | GOBP_AMINE_METABOLIC_PROCESS | GOBP_AMINE_METABOLIC_PROCESS | 16/1438 | 122/23056 | 0.1311475 | 2.102738 | 3.149682 | 0.0037995 | 0.0167879 | 0.0107923 | VCAM1/ATP2B4/TGFB2/SULT1C2/HNMT/KYNU/SLC7A11/TDO2/SNCAIP/MOXD1/GPR37/IDO1/NNMT/SLC7A7/IL4I1/SAT1 | 16 |
| GOBP_NEGATIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 22/1438 | 190/23056 | 0.1157895 | 1.856497 | 3.057466 | 0.0038104 | 0.0168305 | 0.0108197 | TNFRSF4/ZC3H12A/GFI1/NLRP3/SP100/BHLHE40/IRAK2/HES1/MDFI/TNFAIP3/FZD6/PARP10/KLF4/TCF7L2/NFKBIA/NUPR1/NLRC5/BCL3/PRNP/FOXS1/PTGIS/HMOX1 | 22 |
| GOBP_NEGATIVE_REGULATION_OF_SECRETION | GOBP_NEGATIVE_REGULATION_OF_SECRETION | GOBP_NEGATIVE_REGULATION_OF_SECRETION | 20/1438 | 167/23056 | 0.1197605 | 1.920165 | 3.077974 | 0.0038497 | 0.0169988 | 0.0109279 | TNFRSF1B/IL1B/EGF/CRHBP/ADTRP/EDN1/GJA1/INHBA/ANXA1/NOTCH1/TNFRSF1A/SPX/NCKAP1L/RHBDF1/FOXF1/RHBDF2/APOE/IL11/LIF/HMOX1 | 20 |
| GOBP_MONOCYTE_CHEMOTAXIS | GOBP_MONOCYTE_CHEMOTAXIS | GOBP_MONOCYTE_CHEMOTAXIS | 11/1438 | 70/23056 | 0.1571429 | 2.519531 | 3.283834 | 0.0038663 | 0.0170392 | 0.0109539 | SLIT2/PLA2G7/IL6/CCL26/SERPINE1/ANXA1/FLT1/CCL5/TNFRSF11A/DEFB124/PDGFB | 11 |
| GOBP_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | 11/1438 | 70/23056 | 0.1571429 | 2.519531 | 3.283834 | 0.0038663 | 0.0170392 | 0.0109539 | EREG/PRDM6/SHH/NOTCH1/DKK1/BHLHE41/RBPMS2/MYOCD/BMP2/NFATC2/PDGFB | 11 |
| GOBP_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | 11/1438 | 70/23056 | 0.1571429 | 2.519531 | 3.283834 | 0.0038663 | 0.0170392 | 0.0109539 | MCOLN2/IL1B/WNT5A/TLR3/F2RL1/TSLP/IL6/IL4R/MBP/DEFB124/HMOX1 | 11 |
| GOBP_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 11/1438 | 70/23056 | 0.1571429 | 2.519531 | 3.283834 | 0.0038663 | 0.0170392 | 0.0109539 | CSF1/ITPKB/COL3A1/F2RL1/GPR20/NOTCH1/SYNPO2L/APOA1/IGF1/TGM2/LPAR4 | 11 |
| NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | NATSUME_RESPONSE_TO_INTERFERON_BETA_UP | 11/1438 | 70/23056 | 0.1571429 | 2.519531 | 3.283834 | 0.0038663 | 0.0170392 | 0.0109539 | VCAM1/FGF5/HLA-C/PDGFA/PTPRZ1/IL15RA/FAS/IFITM3/TNFSF14/BCL3/NFATC2 | 11 |
| GOBP_RESPONSE_TO_OSMOTIC_STRESS | GOBP_RESPONSE_TO_OSMOTIC_STRESS | GOBP_RESPONSE_TO_OSMOTIC_STRESS | 12/1438 | 80/23056 | 0.1500000 | 2.405007 | 3.246688 | 0.0038663 | 0.0170392 | 0.0109539 | ERRFI1/PTGS2/MYLK/CLDN1/TLR3/ITGA2/AQP1/YBX3/ZFP36L1/RELB/ICOSLG/MLC1 | 12 |
| BIOCARTA_NFAT_PATHWAY | BIOCARTA_NFAT_PATHWAY | BIOCARTA_NFAT_PATHWAY | 9/1438 | 51/23056 | 0.1764706 | 2.829420 | 3.373196 | 0.0039304 | 0.0173049 | 0.0111247 | CAMK1G/AGT/HBEGF/EDN1/IGF1/NFATC4/CTF1/MYH2/NFATC2 | 9 |
| GOBP_POSITIVE_REGULATION_OF_STRESS_FIBER_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_STRESS_FIBER_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_STRESS_FIBER_ASSEMBLY | 9/1438 | 51/23056 | 0.1764706 | 2.829420 | 3.373196 | 0.0039304 | 0.0173049 | 0.0111247 | RHOC/S100A10/CCN2/ARHGEF5/NRP1/SYNPO2L/APOA1/TPM1/SDC4 | 9 |
| HP_ABNORMAL_DENTAL_PULP_MORPHOLOGY | HP_ABNORMAL_DENTAL_PULP_MORPHOLOGY | HP_ABNORMAL_DENTAL_PULP_MORPHOLOGY | 9/1438 | 51/23056 | 0.1764706 | 2.829420 | 3.373196 | 0.0039304 | 0.0173049 | 0.0111247 | LAMB3/TGFA/GALNT3/COL5A2/GJA1/COL5A1/WNT10B/DLX3/COL1A1 | 9 |
| AMIT_EGF_RESPONSE_40_HELA | AMIT_EGF_RESPONSE_40_HELA | AMIT_EGF_RESPONSE_40_HELA | 8/1438 | 42/23056 | 0.1904762 | 3.053977 | 3.436200 | 0.0039548 | 0.0173733 | 0.0111687 | PTGS2/HES1/IER3/IL6/KLF2/ZFP36/BCL3/CEBPB | 8 |
| CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN | 8/1438 | 42/23056 | 0.1904762 | 3.053977 | 3.436200 | 0.0039548 | 0.0173733 | 0.0111687 | TM4SF1/TGFBI/GJA1/NRP1/PLAU/PPP1R3C/RRAD/PTGIS | 8 |
| GOBP_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION | 8/1438 | 42/23056 | 0.1904762 | 3.053977 | 3.436200 | 0.0039548 | 0.0173733 | 0.0111687 | ZC3H12A/CD96/INHBA/CD274/PDCD1LG2/NLRP6/AXL/PRNP | 8 |
| GOBP_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | GOBP_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | GOBP_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION | 8/1438 | 42/23056 | 0.1904762 | 3.053977 | 3.436200 | 0.0039548 | 0.0173733 | 0.0111687 | ERRFI1/PTPRC/PDGFC/VEGFC/PDGFA/GPNMB/CAV1/PDGFB | 8 |
| GOMF_STRUCTURAL_CONSTITUENT_OF_MUSCLE | GOMF_STRUCTURAL_CONSTITUENT_OF_MUSCLE | GOMF_STRUCTURAL_CONSTITUENT_OF_MUSCLE | 8/1438 | 42/23056 | 0.1904762 | 3.053977 | 3.436200 | 0.0039548 | 0.0173733 | 0.0111687 | NEXN/ASPH/TPM2/TPM1/MYH8/KRT19/MYOM1/MYL9 | 8 |
| HP_IMPAIRED_MASTICATION | HP_IMPAIRED_MASTICATION | HP_IMPAIRED_MASTICATION | 8/1438 | 42/23056 | 0.1904762 | 3.053977 | 3.436200 | 0.0039548 | 0.0173733 | 0.0111687 | PTPN22/TGFA/LAMB2/LAMA2/TPM2/PYGM/WNT10B/ITGA7 | 8 |
| HP_SUPERNUMERARY_TOOTH | HP_SUPERNUMERARY_TOOTH | HP_SUPERNUMERARY_TOOTH | 8/1438 | 42/23056 | 0.1904762 | 3.053977 | 3.436200 | 0.0039548 | 0.0173733 | 0.0111687 | HSPG2/KCNN3/WNT5A/ADAMTS3/FAT4/RUNX2/TRPS1/EXT1 | 8 |
| WP_BREAST_CANCER_PATHWAY | WP_BREAST_CANCER_PATHWAY | WP_BREAST_CANCER_PATHWAY | 19/1438 | 156/23056 | 0.1217949 | 1.952783 | 3.079591 | 0.0039633 | 0.0174051 | 0.0111892 | WNT5A/HES1/FGF5/LEF1/EGF/FGF18/FZD1/FGF20/FZD6/NOTCH1/FZD8/NFKB2/TCF7L2/PGR/WNT10B/IGF1/FOS/GADD45B/WNT7B | 19 |
| GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_SYMBIONT | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_SYMBIONT | GOBP_BIOLOGICAL_PROCESS_INVOLVED_IN_INTERACTION_WITH_SYMBIONT | 14/1438 | 101/23056 | 0.1386139 | 2.222449 | 3.175462 | 0.0039692 | 0.0174200 | 0.0111987 | ZC3H12A/FN1/CXCL6/LEF1/F2RL1/CAV2/MBL2/SFTPD/NLRP6/HMGA2/CCL5/ELANE/APOE/APOL1 | 14 |
| WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY | WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY | WP_MICRORNAS_IN_CARDIOMYOCYTE_HYPERTROPHY | 14/1438 | 101/23056 | 0.1386139 | 2.222449 | 3.175462 | 0.0039692 | 0.0174200 | 0.0111987 | IKBKE/AGT/WNT5A/MYLK/EGF/EDN1/FZD1/FGFR2/IGF1/NFATC4/CTF1/MYLK3/TGFB1/LIF | 14 |
| HP_ABNORMALITY_OF_THE_CALF | HP_ABNORMALITY_OF_THE_CALF | HP_ABNORMALITY_OF_THE_CALF | 29/1438 | 275/23056 | 0.1054545 | 1.690793 | 2.972227 | 0.0040262 | 0.0176587 | 0.0113522 | HSPG2/TBX15/FN1/SLCO2A1/FGFR3/NKX3-2/SGMS2/RUNX2/TENT5A/GLI3/TMEM270/MET/SHH/CSGALNACT1/TRPS1/EXT1/TPM2/PAPSS2/FGFR2/SERPINH1/GLI1/FBN1/CYP19A1/COL1A1/SOX9/SCN1B/TGFB1/COL9A3/BGN | 29 |
| AMIT_DELAYED_EARLY_GENES | AMIT_DELAYED_EARLY_GENES | AMIT_DELAYED_EARLY_GENES | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | BHLHE40/HES1/FOSL1/ZFP36L1/ZFP36 | 5 |
| BIOCARTA_CARDIACEGF_PATHWAY | BIOCARTA_CARDIACEGF_PATHWAY | BIOCARTA_CARDIACEGF_PATHWAY | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | AGT/EGF/EDN1/EDNRB/FOS | 5 |
| BOWIE_RESPONSE_TO_TAMOXIFEN | BOWIE_RESPONSE_TO_TAMOXIFEN | BOWIE_RESPONSE_TO_TAMOXIFEN | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | IFI16/IRF9/CCL5/IFI35/MX1 | 5 |
| GOBP_CELLULAR_RESPONSE_TO_EXOGENOUS_DSRNA | GOBP_CELLULAR_RESPONSE_TO_EXOGENOUS_DSRNA | GOBP_CELLULAR_RESPONSE_TO_EXOGENOUS_DSRNA | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | TLR3/STING1/CAV1/DDX58/COLEC12 | 5 |
| GOBP_FEMALE_GENITALIA_DEVELOPMENT | GOBP_FEMALE_GENITALIA_DEVELOPMENT | GOBP_FEMALE_GENITALIA_DEVELOPMENT | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | SRD5A2/WNT5A/CYP19A1/LHX1/AXL | 5 |
| GOBP_LYMPHANGIOGENESIS | GOBP_LYMPHANGIOGENESIS | GOBP_LYMPHANGIOGENESIS | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | EPHA2/TIE1/PTPN14/VEGFC/FOXC1 | 5 |
| GOBP_MAMMARY_GLAND_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_MAMMARY_GLAND_EPITHELIAL_CELL_DIFFERENTIATION | GOBP_MAMMARY_GLAND_EPITHELIAL_CELL_DIFFERENTIATION | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | LBH/ZNF703/FOXB1/FOXF1/CEBPB | 5 |
| GOBP_POSITIVE_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | PLA2G4A/IL1R1/IL1B/IL27RA/IL12RB1 | 5 |
| GOBP_STRIATUM_DEVELOPMENT | GOBP_STRIATUM_DEVELOPMENT | GOBP_STRIATUM_DEVELOPMENT | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | RARB/SLC7A11/INHBA/FOXP2/ALDH1A3 | 5 |
| GOMF_CADHERIN_BINDING_INVOLVED_IN_CELL_CELL_ADHESION | GOMF_CADHERIN_BINDING_INVOLVED_IN_CELL_CELL_ADHESION | GOMF_CADHERIN_BINDING_INVOLVED_IN_CELL_CELL_ADHESION | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | S100A11/ANXA1/KRT18/ANXA2/CDC42EP1 | 5 |
| HP_ABSENT_TOENAIL | HP_ABSENT_TOENAIL | HP_ABSENT_TOENAIL | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | KCNN3/COL7A1/DSP/JUP/GPC4 | 5 |
| HP_ASCENDING_TUBULAR_AORTA_ANEURYSM | HP_ASCENDING_TUBULAR_AORTA_ANEURYSM | HP_ASCENDING_TUBULAR_AORTA_ANEURYSM | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | TGFB2/COL3A1/TGFBR2/FBLN5/FBN1 | 5 |
| HP_BRAIN_STEM_COMPRESSION | HP_BRAIN_STEM_COMPRESSION | HP_BRAIN_STEM_COMPRESSION | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | FGFR3/TENT5A/DKK1/TNFRSF11A/PDGFB | 5 |
| KARAKAS_TGFB1_SIGNALING | KARAKAS_TGFB1_SIGNALING | KARAKAS_TGFB1_SIGNALING | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | FAP/FN1/IL15/MMP2/MT2A | 5 |
| MOREIRA_RESPONSE_TO_TSA_DN | MOREIRA_RESPONSE_TO_TSA_DN | MOREIRA_RESPONSE_TO_TSA_DN | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | RARB/FGF18/NOTCH1/LAT/ICAM1 | 5 |
| SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_UP | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | CXCL2/SERPINE1/FRMD6/MT1X/SOCS3 | 5 |
| TOMIDA_METASTASIS_DN | TOMIDA_METASTASIS_DN | TOMIDA_METASTASIS_DN | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | FOXC1/TRIP6/KRT18/DLX4/SAT1 | 5 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_DN | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_DN | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_DN | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | LTBP1/MYLK/MYL4/COL18A1/ITM2A | 5 |
| WEBER_METHYLATED_IN_COLON_CANCER | WEBER_METHYLATED_IN_COLON_CANCER | WEBER_METHYLATED_IN_COLON_CANCER | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | TGFB2/WWTR1/SHH/ALX4/FOXF1 | 5 |
| WP_NEPHROGENESIS | WP_NEPHROGENESIS | WP_NEPHROGENESIS | 5/1438 | 18/23056 | 0.2777778 | 4.453717 | 3.780549 | 0.0040507 | 0.0176587 | 0.0113522 | OSR1/FOXD1/RSPO3/FGF20/ALDH1A2 | 5 |
| ROPERO_HDAC2_TARGETS | ROPERO_HDAC2_TARGETS | ROPERO_HDAC2_TARGETS | 15/1438 | 112/23056 | 0.1339286 | 2.147328 | 3.139180 | 0.0040795 | 0.0177790 | 0.0114295 | EPHA2/ADCY10/HAPLN1/MOG/RBPMS/ST3GAL1/MYRF/TNFAIP2/SMAD6/SLFN12/GIP/MAG/EMP3/BIRC7/RUNX1 | 15 |
| GOMF_DNA_BINDING_TRANSCRIPTION_REPRESSOR_ACTIVITY | GOMF_DNA_BINDING_TRANSCRIPTION_REPRESSOR_ACTIVITY | GOMF_DNA_BINDING_TRANSCRIPTION_REPRESSOR_ACTIVITY | 33/1438 | 325/23056 | 0.1015385 | 1.628005 | 2.940692 | 0.0040918 | 0.0178270 | 0.0114604 | GFI1/TBX15/PRRX1/BHLHE40/PPARG/MITF/BCL6/HES1/NKX3-2/LEF1/IRX2/SOX30/TFAP2A/TBX18/MAFK/HOXA2/FOXP2/MSC/TRPS1/GLIS3/NACC2/HHEX/CREB3L1/BHLHE41/FOXO1/NFATC4/SALL1/HOXB13/DLX4/FOXS1/CEBPB/NFATC2/TFAP2C | 33 |
| GOBP_RESPONSE_TO_ESTRADIOL | GOBP_RESPONSE_TO_ESTRADIOL | GOBP_RESPONSE_TO_ESTRADIOL | 16/1438 | 123/23056 | 0.1300813 | 2.085643 | 3.113604 | 0.0041212 | 0.0179435 | 0.0115353 | PTGS2/AGT/CASP8/ITGA2/CRHBP/CCN2/PDGFA/ZNF703/ANXA1/CRYAB/CYP19A1/ALDH1A2/MMP2/NQO1/COL1A1/TGFB1 | 16 |
| KARLSSON_TGFB1_TARGETS_UP | KARLSSON_TGFB1_TARGETS_UP | KARLSSON_TGFB1_TARGETS_UP | 16/1438 | 123/23056 | 0.1300813 | 2.085643 | 3.113604 | 0.0041212 | 0.0179435 | 0.0115353 | TNFRSF9/BHLHE40/PTP4A1/CCN2/ZYX/EXT1/CD44/YBX3/HMGA2/NUAK1/MMP14/ANXA2/TPM1/TNFRSF12A/SALL1/MSN | 16 |
| GOBP_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 25/1438 | 227/23056 | 0.1101322 | 1.765791 | 2.990431 | 0.0041600 | 0.0181065 | 0.0116401 | PTGS2/IL1A/IL1B/ITGA6/ACKR3/GDNF/CSF2/VNN1/TNFAIP3/SOD2/SERPINE1/CLU/NRP1/ITPRIP/TCF7L2/CD44/CREB3L1/YAP1/YBX3/IGF1/BMP4/THBS1/NOG/ICAM1/HMOX1 | 25 |
| LU_EZH2_TARGETS_UP | LU_EZH2_TARGETS_UP | LU_EZH2_TARGETS_UP | 30/1438 | 288/23056 | 0.1041667 | 1.670144 | 2.951590 | 0.0041659 | 0.0181267 | 0.0116531 | S100A2/S100A13/TM4SF1/IER3/PSMB8/PSMB9/SOD2/TRIP6/RARRES2/B4GALT1/CLIC3/ZCCHC24/MICAL2/PLAAT4/PRSS23/H2AJ/MSRB3/CPM/OASL/AHNAK2/PSMB10/CLDN7/CD68/MYH4/IFI35/CGB5/CGB8/SDC4/ELFN2/SPANXD | 30 |
| GOBP_AGING | GOBP_AGING | GOBP_AGING | 32/1438 | 313/23056 | 0.1022364 | 1.639195 | 2.936542 | 0.0041935 | 0.0182408 | 0.0117264 | TNFRSF1B/VCAM1/PTGS2/PRELP/AGT/TGFBR2/MME/BCL6/CLDN1/IL15/PLK2/EDN1/CCN2/CITED2/SOD2/SERPINE1/LOXL2/NEK6/DKK1/DNMBP/PITX3/ADM/CRYAB/HMGA2/NUAK1/EDNRB/FOS/MMP2/NQO1/CD68/MBP/PRNP | 32 |
| GOBP_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | GOBP_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY | 10/1438 | 61/23056 | 0.1639344 | 2.628423 | 3.284503 | 0.0042226 | 0.0183501 | 0.0117967 | PTPN22/DDX60/TNFAIP3/DDX58/SLC15A3/BIRC3/OASL/NFKBIA/RNF135/DHX58 | 10 |
| GOMF_COPPER_ION_BINDING | GOMF_COPPER_ION_BINDING | GOMF_COPPER_ION_BINDING | 10/1438 | 61/23056 | 0.1639344 | 2.628423 | 3.284503 | 0.0042226 | 0.0183501 | 0.0117967 | S100A5/S100A13/IL1A/SOD3/MOXD1/LOXL2/LOXL4/LOXL1/PRNP/PRND | 10 |
| POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN | 10/1438 | 61/23056 | 0.1639344 | 2.628423 | 3.284503 | 0.0042226 | 0.0183501 | 0.0117967 | CFH/NID1/COL3A1/C1S/GLI1/NFATC4/LTBP2/ALDH1A3/COL1A1/NDP | 10 |
| GOBP_NEGATIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 12/1438 | 81/23056 | 0.1481481 | 2.375316 | 3.197948 | 0.0042871 | 0.0186070 | 0.0119618 | LTBP1/PPARG/VEPH1/CD109/CAV2/CAV1/HTRA4/HTRA1/BCL9L/FBN1/SMAD6/BMP2 | 12 |
| HP_LUMBAR_HYPERLORDOSIS | HP_LUMBAR_HYPERLORDOSIS | HP_LUMBAR_HYPERLORDOSIS | 12/1438 | 81/23056 | 0.1481481 | 2.375316 | 3.197948 | 0.0042871 | 0.0186070 | 0.0119618 | HSPG2/FUCA1/FN1/COL6A3/FGFR3/COL12A1/TPM2/MYPN/FBN1/PIEZO2/COL6A2/BGN | 12 |
| ROSS_AML_WITH_MLL_FUSIONS | ROSS_AML_WITH_MLL_FUSIONS | ROSS_AML_WITH_MLL_FUSIONS | 12/1438 | 81/23056 | 0.1481481 | 2.375316 | 3.197948 | 0.0042871 | 0.0186070 | 0.0119618 | ELF3/CAPG/SRGN/ALDH3B1/ITGA7/CPM/ALOX5AP/CES1/CCL5/SIRPA/LGALS1/SAGE1 | 12 |
| ROSS_LEUKEMIA_WITH_MLL_FUSIONS | ROSS_LEUKEMIA_WITH_MLL_FUSIONS | ROSS_LEUKEMIA_WITH_MLL_FUSIONS | 12/1438 | 81/23056 | 0.1481481 | 2.375316 | 3.197948 | 0.0042871 | 0.0186070 | 0.0119618 | PTPRC/CAPG/C9/DAB2/HOXA7/ITGA7/CSPG4/CES1/CCL5/MYH9/RAC2/LGALS1 | 12 |
| BURTON_ADIPOGENESIS_2 | BURTON_ADIPOGENESIS_2 | BURTON_ADIPOGENESIS_2 | 11/1438 | 71/23056 | 0.1549296 | 2.484045 | 3.230042 | 0.0043231 | 0.0187392 | 0.0120468 | SPSB1/IL1R1/FST/GJA1/SASH1/ST3GAL1/FOSL1/ITGA5/HMGA2/KRT13/KCNN4 | 11 |
| GOBP_OVULATION_CYCLE | GOBP_OVULATION_CYCLE | GOBP_OVULATION_CYCLE | 11/1438 | 71/23056 | 0.1549296 | 2.484045 | 3.230042 | 0.0043231 | 0.0187392 | 0.0120468 | TGFB2/SLIT2/EREG/INHBA/PTN/HAS2/ANXA1/FZD4/PGR/MMP2/AXL | 11 |
| HP_ABNORMAL_CIRCULATING_IGA_LEVEL | HP_ABNORMAL_CIRCULATING_IGA_LEVEL | HP_ABNORMAL_CIRCULATING_IGA_LEVEL | 11/1438 | 71/23056 | 0.1549296 | 2.484045 | 3.230042 | 0.0043231 | 0.0187392 | 0.0120468 | CASP10/CASP8/IL7R/STING1/PSMB8/TNFSF15/FAS/NFKB2/CAVIN1/TNFRSF11A/IL12RB1 | 11 |
| RAGHAVACHARI_PLATELET_SPECIFIC_GENES | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | 11/1438 | 71/23056 | 0.1549296 | 2.484045 | 3.230042 | 0.0043231 | 0.0187392 | 0.0120468 | MYLK/ITGB5/CXCL5/SPARC/PTGS1/VCL/THBS1/TPM1/CCL5/MAP3K7CL/ZNF185 | 11 |
| HP_ABNORMAL_CLAVICLE_MORPHOLOGY | HP_ABNORMAL_CLAVICLE_MORPHOLOGY | HP_ABNORMAL_CLAVICLE_MORPHOLOGY | 14/1438 | 102/23056 | 0.1372549 | 2.200660 | 3.134333 | 0.0043432 | 0.0188144 | 0.0120951 | TBX15/FGFR3/FAT4/RUNX2/GJA1/GLI3/RSPO2/TNFRSF11B/FGFR2/ALX4/MMP14/MMP2/TNFRSF11A/BGN | 14 |
| HP_DENTAL_CROWDING | HP_DENTAL_CROWDING | HP_DENTAL_CROWDING | 14/1438 | 102/23056 | 0.1372549 | 2.200660 | 3.134333 | 0.0043432 | 0.0188144 | 0.0120951 | COL3A1/WNT5A/EDN1/GJA1/TRPS1/TPM2/COL5A1/FGFR2/ITGA7/GRIP1/FREM2/FBN1/KCNJ2/BMP2 | 14 |
| GOBP_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 18/1438 | 146/23056 | 0.1232877 | 1.976718 | 3.053426 | 0.0043597 | 0.0188741 | 0.0121335 | CCN1/IFI16/NLRP3/CASP10/CASP8/PPARG/FOXL2/CCN2/PERP/ASPH/TNFSF15/GSN/FAS/NLRP6/CASP4/CASP1/BLID/UACA | 18 |
| HP_ABNORMAL_CONJUNCTIVA_MORPHOLOGY | HP_ABNORMAL_CONJUNCTIVA_MORPHOLOGY | HP_ABNORMAL_CONJUNCTIVA_MORPHOLOGY | 18/1438 | 146/23056 | 0.1232877 | 1.976718 | 3.053426 | 0.0043597 | 0.0188741 | 0.0121335 | FUCA1/NLRP3/GALNT3/COL7A1/FGFR3/PSMB8/PSMB9/STX11/SAMD9/GSN/FAS/FGFR2/MMP1/TNFRSF1A/DACT1/FBN1/SALL1/PIEZO1 | 18 |
| BAUS_TFF2_TARGETS_UP | BAUS_TFF2_TARGETS_UP | BAUS_TFF2_TARGETS_UP | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | PTPN22/ABCG2/HLA-E/PSMB8/PSMB9/CRIP1/GGT1 | 7 |
| COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | SERPINE2/DNER/TNFRSF21/SOD2/HTRA1/SOX8/ITGA3 | 7 |
| GOBP_OSTEOBLAST_PROLIFERATION | GOBP_OSTEOBLAST_PROLIFERATION | GOBP_OSTEOBLAST_PROLIFERATION | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | CCN1/NPR3/CTHRC1/FGFR2/SOX8/BMP2/MN1 | 7 |
| GOBP_REGULATION_OF_PRESYNAPSE_ORGANIZATION | GOBP_REGULATION_OF_PRESYNAPSE_ORGANIZATION | GOBP_REGULATION_OF_PRESYNAPSE_ORGANIZATION | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | IL1RAP/MDGA1/FZD1/DKK1/LRFN5/GPC4/SLITRK4 | 7 |
| GOBP_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | WNT5A/IL7R/IDO1/ST3GAL1/CD274/BMP4/CCL5 | 7 |
| GOMF_PHOSPHOLIPASE_A2_ACTIVITY | GOMF_PHOSPHOLIPASE_A2_ACTIVITY | GOMF_PHOSPHOLIPASE_A2_ACTIVITY | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | PLA2G4A/PLA2G7/PLAAT4/PLAAT3/PLA2G4D/PLA2G4C/PNPLA3 | 7 |
| HP_AXIAL_MUSCLE_WEAKNESS | HP_AXIAL_MUSCLE_WEAKNESS | HP_AXIAL_MUSCLE_WEAKNESS | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | DES/COL6A3/LAMB2/COL12A1/TPM2/CRYAB/COL6A2 | 7 |
| HP_NEOPLASM_OF_HEAD_AND_NECK | HP_NEOPLASM_OF_HEAD_AND_NECK | HP_NEOPLASM_OF_HEAD_AND_NECK | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | TGFBR2/MSR1/CTHRC1/COL14A1/RHBDF2/COL4A6/COL4A5 | 7 |
| HP_SUBARACHNOID_HEMORRHAGE | HP_SUBARACHNOID_HEMORRHAGE | HP_SUBARACHNOID_HEMORRHAGE | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | TGFB2/COL3A1/TGFBR2/MYLK/ITGA2/CD109/FBN1 | 7 |
| PID_HIF2PATHWAY | PID_HIF2PATHWAY | PID_HIF2PATHWAY | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | BHLHE40/KDR/ABCG2/CITED2/SERPINE1/FLT1/MMP14 | 7 |
| REACTOME_PLASMA_LIPOPROTEIN_REMODELING | REACTOME_PLASMA_LIPOPROTEIN_REMODELING | REACTOME_PLASMA_LIPOPROTEIN_REMODELING | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | PCSK5/APOC3/APOA1/CETP/LIPG/CREB3L3/APOE | 7 |
| VALK_AML_CLUSTER_3 | VALK_AML_CLUSTER_3 | VALK_AML_CLUSTER_3 | 7/1438 | 34/23056 | 0.2058824 | 3.300990 | 3.462876 | 0.0043955 | 0.0189574 | 0.0121870 | TNFRSF4/CFH/CRYBG1/CEBPD/PIEZO2/SERPINB8/COL4A5 | 7 |
| DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | 25/1438 | 228/23056 | 0.1096491 | 1.758046 | 2.966766 | 0.0044033 | 0.0189850 | 0.0122048 | OLFML3/LONRF2/SEMA3B/COL12A1/TPBG/TPD52L1/MYBL1/NXNL2/MYOF/MICAL2/CD44/CD82/PLAAT3/PRSS23/PGR/PHLDA1/TPM1/CA12/SLC47A1/KRT13/MOCOS/KCNK6/BLVRB/TGM2/ZNF185 | 25 |
| GOBP_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | GOBP_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | 20/1438 | 169/23056 | 0.1183432 | 1.897441 | 3.020016 | 0.0044072 | 0.0189898 | 0.0122079 | AGRN/CSF1/CRABP2/BMP10/FN1/TGFBR2/SEMA5A/EDN1/ZFPM2/NOTCH1/NRP1/FGFR2/WT1/YAP1/YBX3/GLI1/IGF1/TRPV2/GATA6/FOXS1 | 20 |
| OHGUCHI_LIVER_HNF4A_TARGETS_DN | OHGUCHI_LIVER_HNF4A_TARGETS_DN | OHGUCHI_LIVER_HNF4A_TARGETS_DN | 20/1438 | 169/23056 | 0.1183432 | 1.897441 | 3.020016 | 0.0044072 | 0.0189898 | 0.0122079 | S100A10/AADAC/SUCNR1/CLDN1/IL1RAP/CPN2/CFI/C9/PXDC1/SMLR1/PERP/RARRES2/MBL2/NLRP6/BBOX1/SLCO2B1/SOAT2/SERPINA1/CES1/SLC47A1 | 20 |
| HP_HYPERHIDROSIS | HP_HYPERHIDROSIS | HP_HYPERHIDROSIS | 17/1438 | 135/23056 | 0.1259259 | 2.019018 | 3.062572 | 0.0044340 | 0.0190995 | 0.0122784 | FUCA1/PTPN22/LAMC2/LAMB3/NLRP3/COL6A3/SLCO2A1/TENT5A/PERP/BIRC3/KRT17/JUP/ITGB4/SERPINB7/CACNA1A/PRNP/COL6A2 | 17 |
| GOBP_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING | GOBP_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING | GOBP_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING | 15/1438 | 113/23056 | 0.1327434 | 2.128325 | 3.101005 | 0.0044396 | 0.0191175 | 0.0122900 | ZC3H12A/PTPN22/NLRP3/IL1B/NMI/TLR3/EDN1/SASH1/TRIP6/TCIM/NFKBIA/UACA/IFI35/TNFSF14/BCL3 | 15 |
| GOBP_PRESYNAPSE_ORGANIZATION | GOBP_PRESYNAPSE_ORGANIZATION | GOBP_PRESYNAPSE_ORGANIZATION | 9/1438 | 52/23056 | 0.1730769 | 2.775008 | 3.304871 | 0.0044954 | 0.0193337 | 0.0124289 | WNT5A/IL1RAP/MDGA1/FZD1/DKK1/LRFN5/C5AR1/GPC4/SLITRK4 | 9 |
| GOBP_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS | GOBP_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS | GOBP_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS | 9/1438 | 52/23056 | 0.1730769 | 2.775008 | 3.304871 | 0.0044954 | 0.0193337 | 0.0124289 | EDN2/PTGS2/PLA2G4A/IL1B/EDN1/ANXA1/PTGS1/AKR1C3/PTGIS | 9 |
| GOMF_ORGANIC_HYDROXY_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ORGANIC_HYDROXY_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ORGANIC_HYDROXY_COMPOUND_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 9/1438 | 52/23056 | 0.1730769 | 2.775008 | 3.304871 | 0.0044954 | 0.0193337 | 0.0124289 | SLC22A1/AQP1/AQP7/AQP3/SLC5A12/SLCO2B1/SLC10A2/ABCC3/SLC16A3 | 9 |
| WP_NETRINUNC5B_SIGNALING_PATHWAY | WP_NETRINUNC5B_SIGNALING_PATHWAY | WP_NETRINUNC5B_SIGNALING_PATHWAY | 9/1438 | 52/23056 | 0.1730769 | 2.775008 | 3.304871 | 0.0044954 | 0.0193337 | 0.0124289 | VCAM1/IL1A/KDR/CCN2/YAP1/ROBO4/COL1A1/ITGB4/ICAM1 | 9 |
| HP_ABNORMALITY_OF_FONTANELLES | HP_ABNORMALITY_OF_FONTANELLES | HP_ABNORMALITY_OF_FONTANELLES | 21/1438 | 181/23056 | 0.1160221 | 1.860226 | 2.996579 | 0.0045212 | 0.0194384 | 0.0124963 | AGT/NLRP3/WNT5A/FGFR3/FAT4/ADAMTS2/RUNX2/TENT5A/GJA1/FAM20C/BMPER/GLI3/SLC26A4/GLIS3/FGFR2/MMP2/MAF/LHX1/COL1A1/SOX9/PIEZO2 | 21 |
| ALONSO_METASTASIS_DN | ALONSO_METASTASIS_DN | ALONSO_METASTASIS_DN | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | EDN2/IFI44L/ACKR2/PAPPA/FOXO1/CYP19A1 | 6 |
| CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | TDO2/MOXD1/MS4A4A/NNMT/SLC38A4/ALOX5AP | 6 |
| GOBP_BLASTODERM_SEGMENTATION | GOBP_BLASTODERM_SEGMENTATION | GOBP_BLASTODERM_SEGMENTATION | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | NRP2/WNT5A/TDRD6/SEMA3A/NRP1/WT1 | 6 |
| GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT | GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT | GOBP_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | CASP8/MDFI/GCM1/KRT19/SOCS3/LIF | 6 |
| GOBP_HYPEROSMOTIC_RESPONSE | GOBP_HYPEROSMOTIC_RESPONSE | GOBP_HYPEROSMOTIC_RESPONSE | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | ERRFI1/CLDN1/TLR3/AQP1/YBX3/ICOSLG | 6 |
| GOBP_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION | GOBP_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION | GOBP_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | EPHA2/WNT5A/RREB1/ZNF703/STAT6/CEBPB | 6 |
| GOBP_NEGATIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_CHEMOKINE_PRODUCTION | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | EPHA2/F2RL1/IL6/KLF4/ELANE/SIRPA | 6 |
| GOBP_POSITIVE_REGULATION_OF_FOCAL_ADHESION_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_FOCAL_ADHESION_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_FOCAL_ADHESION_ASSEMBLY | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | S100A10/KDR/TEK/NRP1/PTPRJ/SDC4 | 6 |
| GOBP_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | GOBP_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | GOBP_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | BMP6/TNFAIP3/SASH1/CD36/TRIM5/CARD16 | 6 |
| GOMF_HYALURONIC_ACID_BINDING | GOMF_HYALURONIC_ACID_BINDING | GOMF_HYALURONIC_ACID_BINDING | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | SUSD5/STAB1/HAPLN1/CD44/LAYN/HAPLN3 | 6 |
| HOEGERKORP_CD44_TARGETS_DIRECT_UP | HOEGERKORP_CD44_TARGETS_DIRECT_UP | HOEGERKORP_CD44_TARGETS_DIRECT_UP | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | MITF/CFI/ADRB2/IL6/AQP1/PYGL | 6 |
| HP_ANTERIOR_CHAMBER_SYNECHIAE | HP_ANTERIOR_CHAMBER_SYNECHIAE | HP_ANTERIOR_CHAMBER_SYNECHIAE | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | RPE65/PTPN22/FOXC1/COL18A1/IL2RB/NDP | 6 |
| HP_AVASCULAR_NECROSIS_OF_THE_CAPITAL_FEMORAL_EPIPHYSIS | HP_AVASCULAR_NECROSIS_OF_THE_CAPITAL_FEMORAL_EPIPHYSIS | HP_AVASCULAR_NECROSIS_OF_THE_CAPITAL_FEMORAL_EPIPHYSIS | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | FN1/WNT5A/ADAMTS2/TRPS1/EXT1/COL1A1 | 6 |
| HP_URETEROCELE | HP_URETEROCELE | HP_URETEROCELE | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | LAMC2/LAMB3/ITGA6/LHX1/ITGB4/SCN1B | 6 |
| PID_IL27_PATHWAY | PID_IL27_PATHWAY | PID_IL27_PATHWAY | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | IL1B/IL6/EBI3/IL27RA/IL12RB1/TGFB1 | 6 |
| REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | AGRN/HSPG2/CSPG4/SDC4/GPC4/BGN | 6 |
| ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_DN | ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_DN | ROYLANCE_BREAST_CANCER_16Q_COPY_NUMBER_DN | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | MYLK3/MMP2/LPCAT2/CES1/MAF/CDYL2 | 6 |
| WP_MAMMALIAN_DISORDER_OF_SEXUAL_DEVELOPMENT | WP_MAMMALIAN_DISORDER_OF_SEXUAL_DEVELOPMENT | WP_MAMMALIAN_DISORDER_OF_SEXUAL_DEVELOPMENT | 6/1438 | 26/23056 | 0.2307692 | 3.700011 | 3.552707 | 0.0045507 | 0.0194555 | 0.0125073 | FOXL2/FST/FGFR2/WT1/SOX8/SOX9 | 6 |
| BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 | BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 | BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 | 13/1438 | 92/23056 | 0.1413043 | 2.265586 | 3.137012 | 0.0045728 | 0.0195381 | 0.0125604 | HSPG2/RASSF5/CYP26B1/ADAMTS3/RSPO3/HOXA3/PLAG1/HAS2/PTPN3/PAPPA/FOSL1/HMGA2/KCNJ2 | 13 |
| ELVIDGE_HIF1A_TARGETS_DN | ELVIDGE_HIF1A_TARGETS_DN | ELVIDGE_HIF1A_TARGETS_DN | 13/1438 | 92/23056 | 0.1413043 | 2.265586 | 3.137012 | 0.0045728 | 0.0195381 | 0.0125604 | VEGFC/GJA1/CITED2/CAV1/LOXL2/STC1/ADM/FOS/AHNAK2/LOXL1/KRT15/CAVIN1/PDGFB | 13 |
| GOBP_O_GLYCAN_PROCESSING | GOBP_O_GLYCAN_PROCESSING | GOBP_O_GLYCAN_PROCESSING | 8/1438 | 43/23056 | 0.1860465 | 2.982954 | 3.356716 | 0.0045982 | 0.0196100 | 0.0126066 | GALNT5/GALNT3/GALNT15/GXYLT2/GALNT10/ST3GAL1/GALNT9/B3GNT3 | 8 |
| GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_NAD_P_H_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_OF_OXYGEN | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_NAD_P_H_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_OF_OXYGEN | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN_NAD_P_H_AS_ONE_DONOR_AND_INCORPORATION_OF_ONE_ATOM_OF_OXYGEN | 8/1438 | 43/23056 | 0.1860465 | 2.982954 | 3.356716 | 0.0045982 | 0.0196100 | 0.0126066 | CYP4X1/FMO3/CYP26B1/AKR1C3/CYP26A1/MICAL2/CYP46A1/CYP4F11 | 8 |
| HP_CORNEAL_EROSION | HP_CORNEAL_EROSION | HP_CORNEAL_EROSION | 8/1438 | 43/23056 | 0.1860465 | 2.982954 | 3.356716 | 0.0045982 | 0.0196100 | 0.0126066 | TWIST2/COL7A1/FGFR3/TGFBI/FGFR2/WT1/MMP1/COL4A5 | 8 |
| HP_LACK_OF_SKIN_ELASTICITY | HP_LACK_OF_SKIN_ELASTICITY | HP_LACK_OF_SKIN_ELASTICITY | 8/1438 | 43/23056 | 0.1860465 | 2.982954 | 3.356716 | 0.0045982 | 0.0196100 | 0.0126066 | TGFB2/COL5A2/TGFBR2/COL5A1/EFEMP2/FBLN5/FBN1/COL1A1 | 8 |
| HP_SUPRAVENTRICULAR_TACHYCARDIA | HP_SUPRAVENTRICULAR_TACHYCARDIA | HP_SUPRAVENTRICULAR_TACHYCARDIA | 8/1438 | 43/23056 | 0.1860465 | 2.982954 | 3.356716 | 0.0045982 | 0.0196100 | 0.0126066 | CITED2/SEMA3A/SCNN1A/ACTC1/HCN4/GATA6/SCN1B/BMP2 | 8 |
| LUI_THYROID_CANCER_CLUSTER_2 | LUI_THYROID_CANCER_CLUSTER_2 | LUI_THYROID_CANCER_CLUSTER_2 | 8/1438 | 43/23056 | 0.1860465 | 2.982954 | 3.356716 | 0.0045982 | 0.0196100 | 0.0126066 | PPARG/ATP10B/TPM2/ZCCHC24/SCNN1A/NID2/ABCC3/SLC16A3 | 8 |
| GOBP_RESPONSE_TO_PEPTIDE_HORMONE | GOBP_RESPONSE_TO_PEPTIDE_HORMONE | GOBP_RESPONSE_TO_PEPTIDE_HORMONE | 39/1438 | 404/23056 | 0.0965347 | 1.547777 | 2.864806 | 0.0046043 | 0.0196298 | 0.0126193 | C1QTNF12/ERRFI1/RPE65/PTGS2/AGT/SRD5A2/IL1B/COL3A1/CPS1/PPARG/EREG/CRHBP/PCSK1/MZB1/EDN1/CCN2/PDK4/CAV2/CAV1/RARRES2/PLAT/ADCY8/ANXA1/PTPRE/ADM/TNS2/STAT6/FOXO1/EDNRB/ZFP36L1/SLC24A4/FBN1/GLP2R/GRB7/GIP/COL1A1/SOCS3/GDF15/PNPLA3 | 39 |
| GOCC_ACTIN_BASED_CELL_PROJECTION | GOCC_ACTIN_BASED_CELL_PROJECTION | GOCC_ACTIN_BASED_CELL_PROJECTION | 24/1438 | 217/23056 | 0.1105991 | 1.773277 | 2.951757 | 0.0046638 | 0.0198772 | 0.0127784 | VCAM1/RHOC/ACTG2/EPHA4/MYO10/IQGAP2/UTRN/PDGFA/PODXL/ANGPT1/TEK/B4GALT1/TMC1/EPS8L2/CD44/PLEKHG6/EPS8/LCP1/SLC10A2/ACTC1/MYO1E/ITGA3/TGFB1/MSN | 24 |
| GOBP_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | GOBP_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | GOBP_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 18/1438 | 147/23056 | 0.1224490 | 1.963271 | 3.021749 | 0.0046861 | 0.0199662 | 0.0128356 | ZC3H12A/AGT/TGFBR2/F2RL1/TFAP2A/SOD2/CD36/PON3/AKR1C3/ALOX5/MMP3/CRYAB/FOXO1/FBLN5/THBS1/TGFB1/RAC2/PDGFB | 18 |
| HP_ABNORMAL_MYELOID_LEUKOCYTE_MORPHOLOGY | HP_ABNORMAL_MYELOID_LEUKOCYTE_MORPHOLOGY | HP_ABNORMAL_MYELOID_LEUKOCYTE_MORPHOLOGY | 33/1438 | 328/23056 | 0.1006098 | 1.613114 | 2.884377 | 0.0047046 | 0.0200386 | 0.0128822 | NEXN/GFI1/PTPN22/FMO3/NLRP3/NABP1/CASP10/DES/TNNC1/TLR3/IL7R/DSP/CAP2/LAMA4/STX11/SAMD9/SAMD9L/MYPN/VCL/FAS/ANKRD1/BAG3/CRYAB/SLC7A7/ACTC1/TPM1/DSG2/ELANE/APOE/RUNX1/MYH9/RAC2/MSN | 33 |
| PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | 20/1438 | 170/23056 | 0.1176471 | 1.886280 | 2.991332 | 0.0047100 | 0.0200553 | 0.0128929 | S100A10/GYPC/SERPINB1/PLEKHA2/HHEX/ARHGDIB/CPM/TNFRSF19/LCP1/TMEM229B/CRIP1/LACTB/COTL1/CCR7/KLF2/CD22/GMFG/BLVRB/CD37/CHST7 | 20 |
| HP_UPPER_EXTREMITY_JOINT_DISLOCATION | HP_UPPER_EXTREMITY_JOINT_DISLOCATION | HP_UPPER_EXTREMITY_JOINT_DISLOCATION | 12/1438 | 82/23056 | 0.1463415 | 2.346348 | 3.149926 | 0.0047439 | 0.0201673 | 0.0129649 | HSPG2/TBX15/COL5A2/WNT5A/CD96/TENT5A/COL27A1/COL5A1/FBN1/SMAD6/COL1A1/NOG | 12 |
| REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA | REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA | REACTOME_DDX58_IFIH1_MEDIATED_INDUCTION_OF_INTERFERON_ALPHA_BETA | 12/1438 | 82/23056 | 0.1463415 | 2.346348 | 3.149926 | 0.0047439 | 0.0201673 | 0.0129649 | IKBKE/CASP10/CASP8/UBA7/TNFAIP3/DDX58/NFKB2/SAA1/NFKBIA/NLRC5/RNF135/DHX58 | 12 |
| GOBP_INNER_EAR_MORPHOGENESIS | GOBP_INNER_EAR_MORPHOGENESIS | GOBP_INNER_EAR_MORPHOGENESIS | 14/1438 | 103/23056 | 0.1359223 | 2.179294 | 3.093680 | 0.0047451 | 0.0201673 | 0.0129649 | PRRX1/WNT5A/TFAP2A/TBX18/HOXA1/FZD6/CTHRC1/ITGA8/FGFR2/HMX3/SIX1/SIX4/ALDH1A3/SOX9 | 14 |
| GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 14/1438 | 103/23056 | 0.1359223 | 2.179294 | 3.093680 | 0.0047451 | 0.0201673 | 0.0129649 | ARHGEF16/EPHA2/LDLRAP1/GBP1/ATP2B4/LYPD1/EPHA3/LRRC15/NKD2/DAB2/MMP14/ITGA3/TGFB1/PRNP | 14 |
| GOMF_MONOOXYGENASE_ACTIVITY | GOMF_MONOOXYGENASE_ACTIVITY | GOMF_MONOOXYGENASE_ACTIVITY | 14/1438 | 103/23056 | 0.1359223 | 2.179294 | 3.093680 | 0.0047451 | 0.0201673 | 0.0129649 | CYP4X1/FMO3/CYP26B1/CYP39A1/MOXD1/AKR1C3/CYP26A1/MICAL2/CYP46A1/CYP19A1/CYP4F11/PTGIS/CYP24A1/HMOX1 | 14 |
| HP_CHEST_PAIN | HP_CHEST_PAIN | HP_CHEST_PAIN | 14/1438 | 103/23056 | 0.1359223 | 2.179294 | 3.093680 | 0.0047451 | 0.0201673 | 0.0129649 | PTPN22/TGFB2/COL3A1/TGFBR2/TNNC1/MYLK/SLC34A2/SPP1/EXT1/TNFRSF1A/SCNN1A/FBN1/COL4A6/COL4A5 | 14 |
| GOBP_AORTA_DEVELOPMENT | GOBP_AORTA_DEVELOPMENT | GOBP_AORTA_DEVELOPMENT | 10/1438 | 62/23056 | 0.1612903 | 2.586029 | 3.225180 | 0.0047595 | 0.0202097 | 0.0129921 | TGFB2/COL3A1/MYLK/HES1/ADAMTS6/NOTCH1/EFEMP2/SIX1/SMAD6/LOXL1 | 10 |
| GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | 10/1438 | 62/23056 | 0.1612903 | 2.586029 | 3.225180 | 0.0047595 | 0.0202097 | 0.0129921 | GBP5/IFI16/NLRP3/CASP8/WNT5A/F2RL1/IL6/CD36/GSDMD/CASP1 | 10 |
| GOBP_REGULATION_OF_MACROPHAGE_ACTIVATION | GOBP_REGULATION_OF_MACROPHAGE_ACTIVATION | GOBP_REGULATION_OF_MACROPHAGE_ACTIVATION | 10/1438 | 62/23056 | 0.1612903 | 2.586029 | 3.225180 | 0.0047595 | 0.0202097 | 0.0129921 | ZC3H12A/PLA2G4A/PTPRC/WNT5A/IL31RA/ADGRF5/IL6/LRFN5/THBS1/IL4R | 10 |
| GOBP_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | GOBP_REGULATION_OF_ION_TRANSMEMBRANE_TRANSPORT | 45/1438 | 483/23056 | 0.0931677 | 1.493793 | 2.828644 | 0.0047747 | 0.0202682 | 0.0130298 | CTSS/CASQ1/ATP2B4/CNIH3/AGT/OSR1/TMEM37/KCNE4/CRHBP/ADRB2/EDN1/CLIC5/GJA1/TRDN/UTRN/HECW1/CAV1/TCAF2/TMC1/PTPN3/CLIC3/LRRC55/AHNAK/CATSPER1/UBASH3B/CACNA2D4/KCNA5/KCNH3/TPCN1/PRKD1/BDKRB1/RRAD/HAP1/KCNJ2/CACNA1A/SCN1B/FXYD5/KCNK6/KCNN4/KCNA7/CACNG6/PRNP/REM1/JPH2/CLIC6 | 45 |
| GOBP_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 17/1438 | 136/23056 | 0.1250000 | 2.004173 | 3.029177 | 0.0047808 | 0.0202877 | 0.0130422 | GFI1/EPHA4/SEMA3B/WNT5A/HES1/SPP1/SEMA5A/DAB2/SEMA3C/SEMA3A/SEMA3D/NRP1/DKK1/MBP/SEMA6B/MAG/APOE | 17 |
| GOBP_ESTABLISHMENT_OF_TISSUE_POLARITY | GOBP_ESTABLISHMENT_OF_TISSUE_POLARITY | GOBP_ESTABLISHMENT_OF_TISSUE_POLARITY | 11/1438 | 72/23056 | 0.1527778 | 2.449544 | 3.177160 | 0.0048217 | 0.0204361 | 0.0131377 | WNT5A/PRICKLE2/DAB2/RSPO3/FZD1/FZD6/CTHRC1/DKK1/DACT1/CELSR1/GPC4 | 11 |
| GOBP_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 11/1438 | 72/23056 | 0.1527778 | 2.449544 | 3.177160 | 0.0048217 | 0.0204361 | 0.0131377 | DLX1/DLX2/HES1/ID4/HOXA2/GLI3/SHH/NOTCH1/SOX8/SOX9/MAG | 11 |
| GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | GOBP_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | 11/1438 | 72/23056 | 0.1527778 | 2.449544 | 3.177160 | 0.0048217 | 0.0204361 | 0.0131377 | MYLK/CLDN1/HBEGF/RREB1/CD36/SERPINE1/PTN/CCN4/ANXA1/THBS1/THBD | 11 |
| HP_RENAL_DYSPLASIA | HP_RENAL_DYSPLASIA | HP_RENAL_DYSPLASIA | 11/1438 | 72/23056 | 0.1527778 | 2.449544 | 3.177160 | 0.0048217 | 0.0204361 | 0.0131377 | ITGA6/TBX18/GLI3/ITGA8/SIX1/SALL1/ITGB4/PIEZO2/PLVAP/SCN1B/SIX5 | 11 |
| HP_PATENT_DUCTUS_ARTERIOSUS | HP_PATENT_DUCTUS_ARTERIOSUS | HP_PATENT_DUCTUS_ARTERIOSUS | 32/1438 | 316/23056 | 0.1012658 | 1.623633 | 2.878935 | 0.0048331 | 0.0204782 | 0.0131647 | MMP23B/ECE1/HSPG2/KCNN3/TGFB2/KYNU/TGFBR2/CD96/MYLK/FGFR3/PRDM6/FOXC1/RREB1/GJA1/GLI3/TMEM270/SAMD9/CSGALNACT1/FGFR2/WT1/MYRF/DACT1/FBN1/SALL1/MAF/FOXF1/MYOCD/GATA6/COL18A1/USP18/ARSL/GPC4 | 32 |
| DESERT_PERIPORTAL_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | DESERT_PERIPORTAL_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | DESERT_PERIPORTAL_HEPATOCELLULAR_CARCINOMA_SUBCLASS_UP | 19/1438 | 159/23056 | 0.1194969 | 1.915938 | 2.989027 | 0.0048828 | 0.0206823 | 0.0132959 | CDA/ECM1/SRD5A2/CPS1/VIPR1/TDO2/C9/CRHBP/SLC22A1/GPR37/APOA1/C1R/IGF1/SLC46A3/ANPEP/ACSM3/ABCA8/ABCA6/TENM1 | 19 |
| DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | 36/1438 | 367/23056 | 0.0980926 | 1.572757 | 2.852658 | 0.0049031 | 0.0207617 | 0.0133470 | ITGA10/FN1/LAMB2/JCHAIN/ADAMTS3/CXCL1/HFE/IER3/DDR1/GPSM3/PDE1C/EPHB4/TRIP6/CPED1/CPA2/MEST/FZD6/KLF4/ALOX5/DKK1/HKDC1/TCF7L2/PGGHG/NRIP3/MPZL2/YBX3/KRT18/CRISPLD2/PIEZO1/KCNN4/CYP24A1/NCAM2/COL18A1/COL6A2/GGT1/TENM1 | 36 |
| AMIT_EGF_RESPONSE_20_MCF10A | AMIT_EGF_RESPONSE_20_MCF10A | AMIT_EGF_RESPONSE_20_MCF10A | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | MDFI/AQP3/MMP14/THBS1 | 4 |
| BIOCARTA_D4GDI_PATHWAY | BIOCARTA_D4GDI_PATHWAY | BIOCARTA_D4GDI_PATHWAY | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CASP10/CASP8/CASP1/ARHGDIB | 4 |
| BIOCARTA_FIBRINOLYSIS_PATHWAY | BIOCARTA_FIBRINOLYSIS_PATHWAY | BIOCARTA_FIBRINOLYSIS_PATHWAY | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | SERPINE1/PLAT/PLAU/SERPINB2 | 4 |
| CLAUS_PGR_POSITIVE_MENINGIOMA_DN | CLAUS_PGR_POSITIVE_MENINGIOMA_DN | CLAUS_PGR_POSITIVE_MENINGIOMA_DN | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | FSTL1/HEG1/TM4SF1/BACE2 | 4 |
| GOBP_BRANCHING_INVOLVED_IN_PROSTATE_GLAND_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_PROSTATE_GLAND_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_PROSTATE_GLAND_MORPHOGENESIS | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | SHH/FGFR2/BMP4/HOXB13 | 4 |
| GOBP_CELLULAR_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE_STIMULUS | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | EDN1/INHBA/PLAT/NOTCH1 | 4 |
| GOBP_CYTIDINE_METABOLIC_PROCESS | GOBP_CYTIDINE_METABOLIC_PROCESS | GOBP_CYTIDINE_METABOLIC_PROCESS | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CDA/APOBEC3A/APOBEC3G/APOBEC3H | 4 |
| GOBP_CYTIDINE_TO_URIDINE_EDITING | GOBP_CYTIDINE_TO_URIDINE_EDITING | GOBP_CYTIDINE_TO_URIDINE_EDITING | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | RBM47/APOBEC3A/APOBEC3G/APOBEC3H | 4 |
| GOBP_ETHER_BIOSYNTHETIC_PROCESS | GOBP_ETHER_BIOSYNTHETIC_PROCESS | GOBP_ETHER_BIOSYNTHETIC_PROCESS | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | PLA2G4A/ALOX5/LPCAT2/PLA2G4C | 4 |
| GOBP_MESENCHYMAL_TO_EPITHELIAL_TRANSITION_INVOLVED_IN_METANEPHROS_MORPHOGENESIS | GOBP_MESENCHYMAL_TO_EPITHELIAL_TRANSITION_INVOLVED_IN_METANEPHROS_MORPHOGENESIS | GOBP_MESENCHYMAL_TO_EPITHELIAL_TRANSITION_INVOLVED_IN_METANEPHROS_MORPHOGENESIS | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | GDNF/BMP4/SALL1/LIF | 4 |
| GOBP_NEGATIVE_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_NEGATIVE_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_NEGATIVE_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | EPHA4/PTN/APOE/PRNP | 4 |
| GOBP_NEGATIVE_REGULATION_OF_MUSCLE_ADAPTATION | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_ADAPTATION | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_ADAPTATION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | ERRFI1/ATP2B4/PPARG/FOXO1 | 4 |
| GOBP_NEGATIVE_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | LEF1/YBX3/BMP4/TGFB1 | 4 |
| GOBP_NEGATIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | GOBP_NEGATIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | GOBP_NEGATIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | PPARG/DKK1/SMAD6/NOG | 4 |
| GOBP_NEPHRIC_DUCT_MORPHOGENESIS | GOBP_NEPHRIC_DUCT_MORPHOGENESIS | GOBP_NEPHRIC_DUCT_MORPHOGENESIS | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | OSR1/EPHA4/BMP4/LHX1 | 4 |
| GOBP_NEUTROPHIL_MEDIATED_KILLING_OF_SYMBIONT_CELL | GOBP_NEUTROPHIL_MEDIATED_KILLING_OF_SYMBIONT_CELL | GOBP_NEUTROPHIL_MEDIATED_KILLING_OF_SYMBIONT_CELL | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CXCL6/F2RL1/NLRP6/ELANE | 4 |
| GOBP_POSITIVE_REGULATION_OF_OSTEOBLAST_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_OSTEOBLAST_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_OSTEOBLAST_PROLIFERATION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CCN1/CTHRC1/SOX8/BMP2 | 4 |
| GOBP_POSITIVE_REGULATION_OF_PRODUCTION_OF_MIRNAS_INVOLVED_IN_GENE_SILENCING_BY_MIRNA | GOBP_POSITIVE_REGULATION_OF_PRODUCTION_OF_MIRNAS_INVOLVED_IN_GENE_SILENCING_BY_MIRNA | GOBP_POSITIVE_REGULATION_OF_PRODUCTION_OF_MIRNAS_INVOLVED_IN_GENE_SILENCING_BY_MIRNA | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | IL6/BMP4/MYOCD/TGFB1 | 4 |
| GOBP_REGULATION_OF_HEAT_GENERATION | GOBP_REGULATION_OF_HEAT_GENERATION | GOBP_REGULATION_OF_HEAT_GENERATION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | PTGS2/IL1B/EDNRB/TNFRSF11A | 4 |
| GOBP_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION | GOBP_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION | GOBP_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA1_PRODUCTION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | LUM/THBS1/GATA6/SERPINB7 | 4 |
| GOBP_REGULATION_OF_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_REGULATION_OF_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_REGULATION_OF_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | DSP/CAV1/JUP/DSG2 | 4 |
| GOBP_TRIGLYCERIDE_RICH_LIPOPROTEIN_PARTICLE_REMODELING | GOBP_TRIGLYCERIDE_RICH_LIPOPROTEIN_PARTICLE_REMODELING | GOBP_TRIGLYCERIDE_RICH_LIPOPROTEIN_PARTICLE_REMODELING | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | APOC3/APOA1/CETP/APOE | 4 |
| GOBP_WNT_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT | GOBP_WNT_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT | GOBP_WNT_SIGNALING_PATHWAY_INVOLVED_IN_HEART_DEVELOPMENT | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | WNT5A/DKK1/ALPK2/BMP2 | 4 |
| GOCC_MICROFIBRIL | GOCC_MICROFIBRIL | GOCC_MICROFIBRIL | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | LTBP1/EFEMP2/FBN1/ADAMTSL5 | 4 |
| GOMF_CYTIDINE_DEAMINASE_ACTIVITY | GOMF_CYTIDINE_DEAMINASE_ACTIVITY | GOMF_CYTIDINE_DEAMINASE_ACTIVITY | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CDA/APOBEC3A/APOBEC3G/APOBEC3H | 4 |
| HP_ABSENT_PHALANGEAL_CREASE | HP_ABSENT_PHALANGEAL_CREASE | HP_ABSENT_PHALANGEAL_CREASE | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | TBX15/TPM2/NOG/PIEZO2 | 4 |
| HP_BRONCHOCONSTRICTION | HP_BRONCHOCONSTRICTION | HP_BRONCHOCONSTRICTION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | HNMT/ADRB2/PLA2G7/ALOX5 | 4 |
| HP_DECREASED_SERUM_COMPLEMENT_C3 | HP_DECREASED_SERUM_COMPLEMENT_C3 | HP_DECREASED_SERUM_COMPLEMENT_C3 | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CFH/SPP1/CFI/C3 | 4 |
| HP_ELEVATED_DIASTOLIC_BLOOD_PRESSURE | HP_ELEVATED_DIASTOLIC_BLOOD_PRESSURE | HP_ELEVATED_DIASTOLIC_BLOOD_PRESSURE | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | ECE1/AGT/FLT1/PTGIS | 4 |
| HP_ELEVATED_SYSTOLIC_BLOOD_PRESSURE | HP_ELEVATED_SYSTOLIC_BLOOD_PRESSURE | HP_ELEVATED_SYSTOLIC_BLOOD_PRESSURE | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | ECE1/AGT/FLT1/PTGIS | 4 |
| HP_ESOPHAGEAL_CARCINOMA | HP_ESOPHAGEAL_CARCINOMA | HP_ESOPHAGEAL_CARCINOMA | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | TGFBR2/MSR1/CTHRC1/RHBDF2 | 4 |
| HP_INCREASED_C_PEPTIDE_LEVEL | HP_INCREASED_C_PEPTIDE_LEVEL | HP_INCREASED_C_PEPTIDE_LEVEL | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | PPARG/CAV1/FOS/CAVIN1 | 4 |
| HP_INCREASED_ENDOMYSIAL_CONNECTIVE_TISSUE | HP_INCREASED_ENDOMYSIAL_CONNECTIVE_TISSUE | HP_INCREASED_ENDOMYSIAL_CONNECTIVE_TISSUE | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | COL6A3/COL12A1/LAMA2/COL6A2 | 4 |
| HP_LIMITED_NECK_RANGE_OF_MOTION | HP_LIMITED_NECK_RANGE_OF_MOTION | HP_LIMITED_NECK_RANGE_OF_MOTION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | GDF6/MEOX1/NOG/SCN1B | 4 |
| HP_NEONATAL_SHORT_LIMB_SHORT_STATURE | HP_NEONATAL_SHORT_LIMB_SHORT_STATURE | HP_NEONATAL_SHORT_LIMB_SHORT_STATURE | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | FGFR3/GLI1/COL1A1/SOX9 | 4 |
| HP_ST_SEGMENT_DEPRESSION | HP_ST_SEGMENT_DEPRESSION | HP_ST_SEGMENT_DEPRESSION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | TNNC1/CITED2/ACTC1/GATA6 | 4 |
| PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CYP26B1/CLDN1/FST/THBS1 | 4 |
| REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CA13/CA1/CA3/CA12 | 4 |
| SASAKI_TARGETS_OF_TP73_AND_TP63 | SASAKI_TARGETS_OF_TP73_AND_TP63 | SASAKI_TARGETS_OF_TP73_AND_TP63 | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CCN1/IL4R/MT2A/MT1X | 4 |
| SHIN_B_CELL_LYMPHOMA_CLUSTER_6 | SHIN_B_CELL_LYMPHOMA_CLUSTER_6 | SHIN_B_CELL_LYMPHOMA_CLUSTER_6 | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | PTGS2/IL1B/HOXA1/HOXA7 | 4 |
| SOUCEK_MYC_TARGETS | SOUCEK_MYC_TARGETS | SOUCEK_MYC_TARGETS | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | CXCL6/CXCL3/CXCL2/CCL5 | 4 |
| WP_BONE_MORPHOGENIC_PROTEIN_BMP_SIGNALING_AND_REGULATION | WP_BONE_MORPHOGENIC_PROTEIN_BMP_SIGNALING_AND_REGULATION | WP_BONE_MORPHOGENIC_PROTEIN_BMP_SIGNALING_AND_REGULATION | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | RUNX2/SMAD6/NOG/BMP2 | 4 |
| WP_IL10_ANTIINFLAMMATORY_SIGNALING_PATHWAY | WP_IL10_ANTIINFLAMMATORY_SIGNALING_PATHWAY | WP_IL10_ANTIINFLAMMATORY_SIGNALING_PATHWAY | 4/1438 | 12/23056 | 0.3333333 | 5.344460 | 3.882413 | 0.0049756 | 0.0207931 | 0.0133672 | IL1A/IL6/BLVRB/HMOX1 | 4 |
| GOBP_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | GOBP_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | GOBP_REGULATION_OF_SMALL_MOLECULE_METABOLIC_PROCESS | 34/1438 | 342/23056 | 0.0994152 | 1.593962 | 2.854164 | 0.0050029 | 0.0209009 | 0.0134365 | C1QTNF12/CDA/LDLRAP1/GFI1/PTGS2/ATP2B4/IL1B/HRH1/PPARG/SLC4A4/SLC7A11/DAB2/PPP1R3G/BMP6/PDK4/CAV1/ANXA1/AKR1C3/PPP1R3C/PHLDA2/ADM/NNMT/APOC3/APOA1/IGF1/FOXO1/SLC7A7/NUPR1/CES1/GIP/SOX9/C1QTNF1/APOE/BMP2 | 34 |
| MITSIADES_RESPONSE_TO_APLIDIN_UP | MITSIADES_RESPONSE_TO_APLIDIN_UP | MITSIADES_RESPONSE_TO_APLIDIN_UP | 42/1438 | 445/23056 | 0.0943820 | 1.513263 | 2.819773 | 0.0050091 | 0.0209204 | 0.0134490 | CCN1/CTSS/SH2D2A/MR1/LAX1/NUAK2/GALNT3/KCNE4/SP140L/ACKR3/HES1/FOXD1/HBEGF/GMPR/TRIM38/HLA-E/TENT5A/TPBG/EXT1/KLF4/PPP1R3C/IFITM3/FOSL1/SCNN1A/C3AR1/BHLHE41/GLIPR1/IGF1/OASL/ALOX5AP/FOXO1/NFKBIA/COL1A1/ABCA8/GADD45B/TNFSF9/ICAM1/KLF2/BCL3/CEBPB/RUNX1/PDGFB | 42 |
| IWANAGA_CARCINOGENESIS_BY_KRAS_UP | IWANAGA_CARCINOGENESIS_BY_KRAS_UP | IWANAGA_CARCINOGENESIS_BY_KRAS_UP | 20/1438 | 171/23056 | 0.1169591 | 1.875249 | 2.962842 | 0.0050297 | 0.0210001 | 0.0135002 | LGR6/HNMT/GALNT3/TGFBR2/CXCL6/EREG/RAI14/HLA-E/GJA1/FUCA2/CLU/TCIM/ASPH/CREB3L1/BCL9L/IGF1/LDHD/MRC2/PRNP/RUNX1 | 20 |
| HP_PRENATAL_MATERNAL_ABNORMALITY | HP_PRENATAL_MATERNAL_ABNORMALITY | HP_PRENATAL_MATERNAL_ABNORMALITY | 18/1438 | 148/23056 | 0.1216216 | 1.950006 | 2.990320 | 0.0050324 | 0.0210048 | 0.0135032 | CFH/TGFB2/CFAP221/PPARG/TGFBR2/MYLK/MME/CFI/DNAH5/MCIDAS/CCNO/GJA1/ADGRG6/SHH/GAS1/ZIC2/FBN1/CYP19A1 | 18 |
| DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP | DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP | DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP | 9/1438 | 53/23056 | 0.1698113 | 2.722649 | 3.238149 | 0.0051217 | 0.0213385 | 0.0137178 | ATP2B4/PLAC8/SRGN/C11orf21/ALDH3B1/NFE2/SELPLG/ALOX5AP/LCP1 | 9 |
| GOBP_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | GOBP_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | GOBP_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | 9/1438 | 53/23056 | 0.1698113 | 2.722649 | 3.238149 | 0.0051217 | 0.0213385 | 0.0137178 | LMOD1/CCL26/LMOD2/NCKAP1L/CSF3/CCR7/CDC42EP5/CDC42EP1/TENM1 | 9 |
| GOBP_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS | GOBP_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS | GOBP_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS | 9/1438 | 53/23056 | 0.1698113 | 2.722649 | 3.238149 | 0.0051217 | 0.0213385 | 0.0137178 | CITED2/TCIM/NOTCH1/BAG3/CREB3L1/CREB3L3/KLF2/CEBPB/HMOX1 | 9 |
| HP_ABNORMALITY_OF_LIPOPROTEIN_CHOLESTEROL_CONCENTRATION | HP_ABNORMALITY_OF_LIPOPROTEIN_CHOLESTEROL_CONCENTRATION | HP_ABNORMALITY_OF_LIPOPROTEIN_CHOLESTEROL_CONCENTRATION | 9/1438 | 53/23056 | 0.1698113 | 2.722649 | 3.238149 | 0.0051217 | 0.0213385 | 0.0137178 | LDLRAP1/PPARG/PSMB8/APOC3/APOA1/SLC7A7/CETP/CREB3L3/APOE | 9 |
| SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_DN | 9/1438 | 53/23056 | 0.1698113 | 2.722649 | 3.238149 | 0.0051217 | 0.0213385 | 0.0137178 | PRRX1/LYPD1/COL8A1/SPON2/TGFBI/INHBA/PLAT/HMGA2/NUAK1 | 9 |
| SMIRNOV_RESPONSE_TO_IR_2HR_UP | SMIRNOV_RESPONSE_TO_IR_2HR_UP | SMIRNOV_RESPONSE_TO_IR_2HR_UP | 9/1438 | 53/23056 | 0.1698113 | 2.722649 | 3.238149 | 0.0051217 | 0.0213385 | 0.0137178 | SLC7A11/PLK2/IER3/FAS/FOSL1/RRAD/SOX9/TNFSF9/GDF15 | 9 |
| HP_ABNORMAL_ENCHONDRAL_OSSIFICATION | HP_ABNORMAL_ENCHONDRAL_OSSIFICATION | HP_ABNORMAL_ENCHONDRAL_OSSIFICATION | 17/1438 | 137/23056 | 0.1240876 | 1.989543 | 2.996067 | 0.0051494 | 0.0214476 | 0.0137879 | HSPG2/PTCH2/THRB/CD96/FGFRL1/NKX3-2/SLC34A2/RUNX2/BMPER/RSPO2/FGFR2/CYP19A1/SOX9/COL9A3/ARSL/GPC4/BGN | 17 |
| HP_SLEEP_APNEA | HP_SLEEP_APNEA | HP_SLEEP_APNEA | 14/1438 | 104/23056 | 0.1346154 | 2.158340 | 3.053490 | 0.0051765 | 0.0215265 | 0.0138387 | AGRN/COL3A1/LAMB2/FGFR3/EDN1/RUNX2/SIM1/GSN/DKK1/COL13A1/FGFR2/LRRC32/BMP2/SRPX2 | 14 |
| GOBP_CARBOXYLIC_ACID_TRANSPORT | GOBP_CARBOXYLIC_ACID_TRANSPORT | GOBP_CARBOXYLIC_ACID_TRANSPORT | 29/1438 | 280/23056 | 0.1035714 | 1.660600 | 2.868356 | 0.0051844 | 0.0215265 | 0.0138387 | SLC1A7/PLA2G4A/AGT/IL1A/IL1B/SLCO2A1/ABCG2/SLC7A11/SLC6A7/EDN1/GJA1/CD36/SLC26A4/SLC26A7/ANXA1/SLC16A12/SLC5A12/SLCO2B1/SLC6A13/TRPC4/SLC10A2/SLC7A7/CES1/SLC47A1/ABCC3/SLC16A5/SLC16A3/TNFRSF11A/SLC7A10 | 29 |
| GOBP_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY | 22/1438 | 195/23056 | 0.1128205 | 1.808894 | 2.925604 | 0.0051968 | 0.0215265 | 0.0138387 | CCN1/IFI16/NLRP3/CASP10/CASP8/FN1/EPHA4/PPARG/FOXL2/CCN2/PERP/CAV1/ASPH/TNFSF15/GSN/FAS/NLRP6/CASP4/CASP1/BLID/UACA/MBP | 22 |
| ALONSO_METASTASIS_EMT_UP | ALONSO_METASTASIS_EMT_UP | ALONSO_METASTASIS_EMT_UP | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | SPARC/FZD1/EMP1/LUM/EDNRB/MMP2/DSG2 | 7 |
| GOBP_BRANCHING_INVOLVED_IN_BLOOD_VESSEL_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_BLOOD_VESSEL_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_BLOOD_VESSEL_MORPHOGENESIS | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | TGFBR2/KDR/LEF1/EDN1/SHH/NRP1/NFATC4 | 7 |
| GOBP_CELLULAR_RESPONSE_TO_FATTY_ACID | GOBP_CELLULAR_RESPONSE_TO_FATTY_ACID | GOBP_CELLULAR_RESPONSE_TO_FATTY_ACID | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | ZC3H12A/CPS1/CLDN1/HES1/EDN1/PDK4/AKR1C3 | 7 |
| GOBP_HINDLIMB_MORPHOGENESIS | GOBP_HINDLIMB_MORPHOGENESIS | GOBP_HINDLIMB_MORPHOGENESIS | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | OSR1/RARB/SHH/RSPO2/NOTCH1/ALX4/BMP4 | 7 |
| GOBP_REGULATION_OF_CARDIOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_CARDIOCYTE_DIFFERENTIATION | GOBP_REGULATION_OF_CARDIOCYTE_DIFFERENTIATION | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | TGFB2/DKK1/BMP4/MYOCD/GATA6/TGFB1/BMP2 | 7 |
| GOBP_RESPONSE_TO_VITAMIN_D | GOBP_RESPONSE_TO_VITAMIN_D | GOBP_RESPONSE_TO_VITAMIN_D | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | PTGS2/SPP1/IL15/STC1/AQP3/CYP24A1/MN1 | 7 |
| HP_CHRONIC_PULMONARY_OBSTRUCTION | HP_CHRONIC_PULMONARY_OBSTRUCTION | HP_CHRONIC_PULMONARY_OBSTRUCTION | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | PTPN22/MCIDAS/RREB1/MMP1/SERPINA1/HMOX1/RAC2 | 7 |
| HP_PERICARDITIS | HP_PERICARDITIS | HP_PERICARDITIS | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | PTPN22/FCGR2A/PRG4/IL6/FAS/TNFRSF1A/MAF | 7 |
| QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | 7/1438 | 35/23056 | 0.2000000 | 3.206676 | 3.369494 | 0.0052040 | 0.0215265 | 0.0138387 | LBH/F2RL1/CITED2/GPRC5A/ITGA5/SLC16A3/COL6A2 | 7 |
| GOBP_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | GOBP_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | GOBP_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | IFI16/CASP8/PERP/ASPH/NLRP6 | 5 |
| GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN | GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN | GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | ERAP2/HFE/HLA-E/HLA-C/TAPBP | 5 |
| GOBP_GROWTH_PLATE_CARTILAGE_DEVELOPMENT | GOBP_GROWTH_PLATE_CARTILAGE_DEVELOPMENT | GOBP_GROWTH_PLATE_CARTILAGE_DEVELOPMENT | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | RARB/TGFBR2/STC1/COL27A1/SOX9 | 5 |
| GOBP_NEGATIVE_REGULATION_OF_MACROPHAGE_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_MACROPHAGE_ACTIVATION | GOBP_NEGATIVE_REGULATION_OF_MACROPHAGE_ACTIVATION | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | ZC3H12A/PTPRC/IL31RA/ADGRF5/LRFN5 | 5 |
| GOBP_PERICARDIUM_DEVELOPMENT | GOBP_PERICARDIUM_DEVELOPMENT | GOBP_PERICARDIUM_DEVELOPMENT | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | WNT5A/HEG1/NOTCH1/WT1/BMP2 | 5 |
| GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | CSF1/AGT/CSF2/CD36/MSR1 | 5 |
| GOBP_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | IKBKE/WNT5A/STING1/TRIM56/NLRC5 | 5 |
| GOBP_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT | GOBP_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT | GOBP_REGULATION_OF_HAIR_FOLLICLE_DEVELOPMENT | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | TGFB2/WNT5A/FST/WNT10B/KRT17 | 5 |
| GOMF_EPHRIN_RECEPTOR_ACTIVITY | GOMF_EPHRIN_RECEPTOR_ACTIVITY | GOMF_EPHRIN_RECEPTOR_ACTIVITY | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | EPHA2/EPHA4/EPHA3/EPHB4/EPHB6 | 5 |
| HP_ABNORMALITY_OF_THE_MIDDLE_PHALANX_OF_THE_5TH_FINGER | HP_ABNORMALITY_OF_THE_MIDDLE_PHALANX_OF_THE_5TH_FINGER | HP_ABNORMALITY_OF_THE_MIDDLE_PHALANX_OF_THE_5TH_FINGER | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | WNT5A/RUNX2/GJA1/NOG/BMP2 | 5 |
| HP_ABNORMALITY_OF_THE_PERIUNGUAL_REGION | HP_ABNORMALITY_OF_THE_PERIUNGUAL_REGION | HP_ABNORMALITY_OF_THE_PERIUNGUAL_REGION | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | LAMC2/LAMB3/STING1/NFKB2/KRT17 | 5 |
| HP_DESCENDING_AORTIC_DISSECTION | HP_DESCENDING_AORTIC_DISSECTION | HP_DESCENDING_AORTIC_DISSECTION | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | TGFB2/COL3A1/TGFBR2/MYLK/FBN1 | 5 |
| HP_EXANTHEM | HP_EXANTHEM | HP_EXANTHEM | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | NLRP3/STX11/TNFRSF1A/EPB42/RUNX1 | 5 |
| HP_PAROXYSMAL_ATRIAL_FIBRILLATION | HP_PAROXYSMAL_ATRIAL_FIBRILLATION | HP_PAROXYSMAL_ATRIAL_FIBRILLATION | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | TRDN/KCNA5/MYL4/KCNJ2/SCN1B | 5 |
| HP_PATCHY_HYPOPIGMENTATION_OF_HAIR | HP_PATCHY_HYPOPIGMENTATION_OF_HAIR | HP_PATCHY_HYPOPIGMENTATION_OF_HAIR | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | PTPN22/MITF/TFAP2A/FAS/EDNRB | 5 |
| HUMMERICH_BENIGN_SKIN_TUMOR_DN | HUMMERICH_BENIGN_SKIN_TUMOR_DN | HUMMERICH_BENIGN_SKIN_TUMOR_DN | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | MYH8/MYH4/MYH1/MYH2/CKM | 5 |
| LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP | LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP | LANDIS_ERBB2_BREAST_PRENEOPLASTIC_UP | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | FRRS1/NPNT/CD82/DSG2/KCNN4 | 5 |
| MATZUK_EMBRYONIC_GERM_CELL | MATZUK_EMBRYONIC_GERM_CELL | MATZUK_EMBRYONIC_GERM_CELL | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | FST/GJA1/STRA8/WT1/BMP4 | 5 |
| SHIN_B_CELL_LYMPHOMA_CLUSTER_5 | SHIN_B_CELL_LYMPHOMA_CLUSTER_5 | SHIN_B_CELL_LYMPHOMA_CLUSTER_5 | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | GFI1/IL6/SOCS3/BCL3/CEBPB | 5 |
| VERNOCHET_ADIPOGENESIS | VERNOCHET_ADIPOGENESIS | VERNOCHET_ADIPOGENESIS | 5/1438 | 19/23056 | 0.2631579 | 4.219310 | 3.620603 | 0.0052186 | 0.0215265 | 0.0138387 | AGT/PPARG/RARRES2/FABP4/LUM | 5 |
| BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN | BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN | BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_DN | 19/1438 | 160/23056 | 0.1187500 | 1.903964 | 2.959276 | 0.0052258 | 0.0215498 | 0.0138536 | LAMB3/ACTG2/IER3/MSR1/PTPN3/TRAF1/PAEP/FBN1/CYP19A1/LOXL1/CTF1/CD68/GRB7/KRT17/ITGA3/SGCA/CKM/NPAS1/CEBPB | 19 |
| GOBP_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS | GOBP_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS | GOBP_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS | 15/1438 | 115/23056 | 0.1304348 | 2.091310 | 3.025835 | 0.0052372 | 0.0215832 | 0.0138751 | EDN2/PTGS2/PLA2G4A/IL1B/MGLL/EDN1/ANXA1/PTGR1/PTGS1/AKR1C3/ALOX5/TNFRSF1A/CYP4F11/PLA2G4C/PTGIS | 15 |
| HP_ARACHNODACTYLY | HP_ARACHNODACTYLY | HP_ARACHNODACTYLY | 15/1438 | 115/23056 | 0.1304348 | 2.091310 | 3.025835 | 0.0052372 | 0.0215832 | 0.0138751 | PTCH2/TGFB2/CYP26B1/ACTG2/TGFBR2/MYLK/FGFR3/RREB1/FGFR2/EFEMP2/C1R/FBLN5/FBN1/BNC1/PIEZO2 | 15 |
| HP_ABNORMAL_BILIARY_TRACT_MORPHOLOGY | HP_ABNORMAL_BILIARY_TRACT_MORPHOLOGY | HP_ABNORMAL_BILIARY_TRACT_MORPHOLOGY | 12/1438 | 83/23056 | 0.1445783 | 2.318079 | 3.102601 | 0.0052386 | 0.0215832 | 0.0138751 | FCGR2A/CLDN1/HFE/PTPN3/TNFSF15/SERPINA1/IL21R/GATA6/IL12RB1/TGFB1/KCNN4/HMOX1 | 12 |
| HP_CORNEAL_OPACITY | HP_CORNEAL_OPACITY | HP_CORNEAL_OPACITY | 28/1438 | 268/23056 | 0.1044776 | 1.675129 | 2.867183 | 0.0052841 | 0.0217642 | 0.0139915 | FUCA1/PTPN22/NLRP3/TWIST2/COL7A1/SLC4A4/TGFBI/FOXC1/PSMB8/TENT5A/GJA1/TMEM270/COLEC10/PITX3/WT1/YAP1/MMP1/APOA1/MMP14/BMP4/LTBP2/MMP2/MAF/APOE/COL18A1/IL2RB/PDGFB/NDP | 28 |
| GOBP_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 8/1438 | 44/23056 | 0.1818182 | 2.915160 | 3.279506 | 0.0053190 | 0.0218753 | 0.0140629 | GBP1/PTPN22/PTPRJ/TESPA1/CCR7/KCNN4/NECTIN2/PRNP | 8 |
| GOBP_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY | GOBP_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY | GOBP_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY | 8/1438 | 44/23056 | 0.1818182 | 2.915160 | 3.279506 | 0.0053190 | 0.0218753 | 0.0140629 | PTPN22/RAB7B/NMI/TNIP3/F2RL1/TNFAIP3/NFKBIA/IFI35 | 8 |
| HALLMARK_APICAL_SURFACE | HALLMARK_APICAL_SURFACE | HALLMARK_APICAL_SURFACE | 8/1438 | 44/23056 | 0.1818182 | 2.915160 | 3.279506 | 0.0053190 | 0.0218753 | 0.0140629 | MDGA1/CRYBG1/EPHB4/ATP6V0A4/B4GALT1/GAS1/LYPD3/IL2RB | 8 |
| HP_THORACIC_SCOLIOSIS | HP_THORACIC_SCOLIOSIS | HP_THORACIC_SCOLIOSIS | 8/1438 | 44/23056 | 0.1818182 | 2.915160 | 3.279506 | 0.0053190 | 0.0218753 | 0.0140629 | AGRN/DES/DOK7/SH3TC2/TPM2/MYPN/COL13A1/SGCA | 8 |
| REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_DEATH_GENES | REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_DEATH_GENES | REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_DEATH_GENES | 8/1438 | 44/23056 | 0.1818182 | 2.915160 | 3.279506 | 0.0053190 | 0.0218753 | 0.0140629 | CASP10/BCL6/PERP/TNFRSF10C/TNFRSF10A/AIFM2/FAS/CASP1 | 8 |
| GOBP_REGULATION_OF_SPROUTING_ANGIOGENESIS | GOBP_REGULATION_OF_SPROUTING_ANGIOGENESIS | GOBP_REGULATION_OF_SPROUTING_ANGIOGENESIS | 10/1438 | 63/23056 | 0.1587302 | 2.544981 | 3.167013 | 0.0053485 | 0.0219701 | 0.0141238 | FGF18/BMPER/CEMIP2/KLF4/JCAD/ALOX5/CREB3L1/ITGA5/THBS1/KLF2 | 10 |
| GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | GOBP_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION | 10/1438 | 63/23056 | 0.1587302 | 2.544981 | 3.167013 | 0.0053485 | 0.0219701 | 0.0141238 | PTGS2/IL1A/IL1B/ADAMTS3/IL6/SULF1/C3AR1/C3/TGFB1/C5AR1 | 10 |
| PID_MYC_REPRESS_PATHWAY | PID_MYC_REPRESS_PATHWAY | PID_MYC_REPRESS_PATHWAY | 10/1438 | 63/23056 | 0.1587302 | 2.544981 | 3.167013 | 0.0053485 | 0.0219701 | 0.0141238 | GFI1/ITGA6/WNT5A/CLU/CEBPD/DKK1/ZFP36L1/CCL5/ITGB4/LGALS1 | 10 |
| REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | 10/1438 | 63/23056 | 0.1587302 | 2.544981 | 3.167013 | 0.0053485 | 0.0219701 | 0.0141238 | AGRN/COL3A1/COL5A2/COL6A3/GDNF/COL5A1/PRNP/COL9A3/COL6A2/COL4A5 | 10 |
| LEE_AGING_CEREBELLUM_DN | LEE_AGING_CEREBELLUM_DN | LEE_AGING_CEREBELLUM_DN | 11/1438 | 73/23056 | 0.1506849 | 2.415989 | 3.125159 | 0.0053648 | 0.0220241 | 0.0141585 | CCN1/UBA7/CSF2/LMOD2/CLIC3/NFKB2/SERPINH1/ZIC2/THBS1/MYL4/ITM2A | 11 |
| WP_FOLATE_METABOLISM | WP_FOLATE_METABOLISM | WP_FOLATE_METABOLISM | 11/1438 | 73/23056 | 0.1506849 | 2.415989 | 3.125159 | 0.0053648 | 0.0220241 | 0.0141585 | CSF1/IL1B/SOD3/SOD2/IL6/SERPINE1/PLAT/NFKB2/SAA1/APOA1/ICAM1 | 11 |
| GOBP_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | GOBP_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 18/1438 | 149/23056 | 0.1208054 | 1.936918 | 2.959137 | 0.0053993 | 0.0221591 | 0.0142453 | RPE65/IGFN1/ATP2B4/TGFB2/DLX1/DLX2/THRB/LAMB2/TFAP2A/TSPAN12/CRB2/NRP1/CABP4/FZD4/SOX8/LHX1/SOX9/NDP | 18 |
| GOCC_PLASMA_MEMBRANE_SIGNALING_RECEPTOR_COMPLEX | GOCC_PLASMA_MEMBRANE_SIGNALING_RECEPTOR_COMPLEX | GOCC_PLASMA_MEMBRANE_SIGNALING_RECEPTOR_COMPLEX | 31/1438 | 306/23056 | 0.1013072 | 1.624297 | 2.835406 | 0.0054487 | 0.0223550 | 0.0143713 | ITGA10/HJV/CNIH3/ITGB6/ITGA6/ITGA4/TGFBR2/ITGB5/GRID2/OSMR/ITGA2/CSF2/HFE/ITGB8/IL6/TRAF1/ITGA8/APBB1IP/TSPAN32/EPS8/ITGA5/ITGA7/ITGA11/ITGA3/ITGB4/IL27RA/IL12RB1/PSG9/BMP2/IL2RB/IL13RA1 | 31 |
| GOBP_AXIS_SPECIFICATION | GOBP_AXIS_SPECIFICATION | GOBP_AXIS_SPECIFICATION | 13/1438 | 94/23056 | 0.1382979 | 2.217382 | 3.050284 | 0.0055014 | 0.0225510 | 0.0144973 | WNT5A/IRX4/MDFI/TDRD6/CITED2/PKD1L1/SHH/STC1/NOTCH1/WT1/BMP4/SMAD6/LHX1 | 13 |
| GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | 13/1438 | 94/23056 | 0.1382979 | 2.217382 | 3.050284 | 0.0055014 | 0.0225510 | 0.0144973 | SERPINE2/RHAG/CD36/CA1/AQP3/HBD/MICAL2/TPM1/LAT/CCL5/SERPINB2/BLVRB/APOE | 13 |
| REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | 13/1438 | 94/23056 | 0.1382979 | 2.217382 | 3.050284 | 0.0055014 | 0.0225510 | 0.0144973 | LYPD1/LYPD6B/MDGA1/CD109/VNN1/VNN2/LY6K/TECTB/OPCML/CPM/MSLN/LYPD3/PRND | 13 |
| HP_JOINT_HYPERMOBILITY | HP_JOINT_HYPERMOBILITY | HP_JOINT_HYPERMOBILITY | 35/1438 | 357/23056 | 0.0980392 | 1.571900 | 2.808698 | 0.0055265 | 0.0226469 | 0.0145589 | PTPN22/KCNN3/TGFB2/COL3A1/COL5A2/COL6A3/TGFBR2/FGFR3/SEMA5A/ADAMTS2/RREB1/COL12A1/TENT5A/TMEM270/SHH/CSGALNACT1/TRPS1/EXT1/COL5A1/CREB3L1/EFEMP2/TNFRSF1A/C1S/C1R/ZIC2/FBLN5/FBN1/COL1A1/RRAS/RIN2/COL9A3/COL18A1/COL6A2/IL2RB/BGN | 35 |
| GOBP_DETECTION_OF_ABIOTIC_STIMULUS | GOBP_DETECTION_OF_ABIOTIC_STIMULUS | GOBP_DETECTION_OF_ABIOTIC_STIMULUS | 17/1438 | 138/23056 | 0.1231884 | 1.975127 | 2.963237 | 0.0055409 | 0.0226506 | 0.0145613 | RPE65/SERPINE2/TRPM8/CDS1/TRPC3/ITGA2/PKD1L1/TRPA1/TMC1/CABP4/CACNA2D4/SLC24A4/PIEZO1/JUP/GNGT2/PIEZO2/GUCY2F | 17 |
| GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREEN_UP | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | SERPINE2/SGMS2/AKR1B10/TNFRSF10A/IFNE/SOCS3 | 6 |
| GOBP_ATRIOVENTRICULAR_VALVE_DEVELOPMENT | GOBP_ATRIOVENTRICULAR_VALVE_DEVELOPMENT | GOBP_ATRIOVENTRICULAR_VALVE_DEVELOPMENT | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | CCN1/TGFB2/TGFBR2/NOTCH1/SMAD6/BMP2 | 6 |
| GOBP_ETHER_METABOLIC_PROCESS | GOBP_ETHER_METABOLIC_PROCESS | GOBP_ETHER_METABOLIC_PROCESS | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | PLA2G4A/PLA2G7/ALOX5/PLAAT3/LPCAT2/PLA2G4C | 6 |
| GOBP_NEGATIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | DLX1/DLX2/HES1/ID4/NOTCH1/NOG | 6 |
| GOBP_NITRIC_OXIDE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_NITRIC_OXIDE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_NITRIC_OXIDE_MEDIATED_SIGNAL_TRANSDUCTION | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | ATP2B4/AGT/CD36/THBS1/APOE/FPR1 | 6 |
| GOBP_RENAL_TUBULAR_SECRETION | GOBP_RENAL_TUBULAR_SECRETION | GOBP_RENAL_TUBULAR_SECRETION | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | AGT/ABCG2/EDN1/STC1/SPX/EDNRB | 6 |
| LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_2_UP | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | CRABP2/HOXA1/HMGA2/IGF1/MEOX1/NCAM2 | 6 |
| NAKAMURA_CANCER_MICROENVIRONMENT_UP | NAKAMURA_CANCER_MICROENVIRONMENT_UP | NAKAMURA_CANCER_MICROENVIRONMENT_UP | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | COL3A1/POSTN/CTF1/COL1A1/SOX9/APOE | 6 |
| PID_GLYPICAN_1PATHWAY | PID_GLYPICAN_1PATHWAY | PID_GLYPICAN_1PATHWAY | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | TGFB2/TGFBR2/SLIT2/FLT1/TGFB1/PRNP | 6 |
| REACTOME_PYROPTOSIS | REACTOME_PYROPTOSIS | REACTOME_PYROPTOSIS | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | IL1A/IL1B/GSDMD/CASP4/CASP1/ELANE | 6 |
| WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING | WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING | WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING | 6/1438 | 27/23056 | 0.2222222 | 3.562973 | 3.436708 | 0.0055471 | 0.0226506 | 0.0145613 | DNER/HES1/LEF1/NOTCH1/MAML2/RRAS | 6 |
| HP_ABNORMALITY_OF_THE_SPINAL_CORD | HP_ABNORMALITY_OF_THE_SPINAL_CORD | HP_ABNORMALITY_OF_THE_SPINAL_CORD | 32/1438 | 319/23056 | 0.1003135 | 1.608364 | 2.821932 | 0.0055531 | 0.0226682 | 0.0145726 | PTCH2/TGFB2/TGFBR2/MYLK/FGFRL1/RREB1/HFE/RUNX2/TENT5A/BMPER/GLI3/TMEM270/SHH/GDF6/EXT1/COLEC10/DKK1/PLAU/ALX4/HMGA2/GRIP1/FREM2/ZIC2/DACT1/FBN1/FOXF1/MEOX1/ITGB4/TNFRSF11A/APOE/BMP2/ARSL | 32 |
| HP_DEPRESSED_NASAL_RIDGE | HP_DEPRESSED_NASAL_RIDGE | HP_DEPRESSED_NASAL_RIDGE | 15/1438 | 116/23056 | 0.1293103 | 2.073282 | 2.988824 | 0.0056774 | 0.0231686 | 0.0148943 | MMP23B/HSPG2/TWIST2/FAM20C/BMPER/GLI3/SHH/FGF20/GAS1/ITGA8/ALX4/ZIC2/SOX9/MN1/ARSL | 15 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | GOBP_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | GOBP_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 12/1438 | 84/23056 | 0.1428571 | 2.290483 | 3.055953 | 0.0057735 | 0.0235467 | 0.0151374 | ZC3H12A/PTGS2/WWTR1/GLI3/SHH/BAG3/YAP1/PRKD1/JUP/TGFB1/LIF/CARD10 | 12 |
| PID_CMYB_PATHWAY | PID_CMYB_PATHWAY | PID_CMYB_PATHWAY | 12/1438 | 84/23056 | 0.1428571 | 2.290483 | 3.055953 | 0.0057735 | 0.0235467 | 0.0151374 | PTGS2/CD34/HES1/LEF1/LECT2/CEBPD/CA1/BIRC3/ANPEP/MAF/ELANE/CEBPB | 12 |
| HP_JOINT_HYPERFLEXIBILITY | HP_JOINT_HYPERFLEXIBILITY | HP_JOINT_HYPERFLEXIBILITY | 21/1438 | 185/23056 | 0.1135135 | 1.820005 | 2.888113 | 0.0058107 | 0.0236606 | 0.0152106 | TGFB2/COL3A1/TGFBR2/FGFR3/SEMA5A/ADAMTS2/RREB1/TENT5A/TMEM270/SHH/TRPS1/EXT1/C1S/C1R/ZIC2/FBLN5/FBN1/COL1A1/RRAS/COL9A3/COL18A1 | 21 |
| GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL_INVOLVED_IN_CONTRACTION | 9/1438 | 54/23056 | 0.1666667 | 2.672230 | 3.172958 | 0.0058135 | 0.0236606 | 0.0152106 | KCNE4/DSP/GJA1/CAV1/KCNA5/JUP/KCNJ2/DSG2/SCN1B | 9 |
| GOBP_CELLULAR_RESPONSE_TO_CAMP | GOBP_CELLULAR_RESPONSE_TO_CAMP | GOBP_CELLULAR_RESPONSE_TO_CAMP | 9/1438 | 54/23056 | 0.1666667 | 2.672230 | 3.172958 | 0.0058135 | 0.0236606 | 0.0152106 | CPS1/CRHBP/AHR/AQP1/STC1/WT1/WNT10B/ZFP36L1/HCN4 | 9 |
| GOBP_POSITIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS | GOBP_POSITIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS | 9/1438 | 54/23056 | 0.1666667 | 2.672230 | 3.172958 | 0.0058135 | 0.0236606 | 0.0152106 | LDLRAP1/EGF/DAB2/HFE/SERPINE1/CLU/ANGPT1/ANXA2/C3 | 9 |
| GOBP_REGULATION_OF_MYOBLAST_DIFFERENTIATION | GOBP_REGULATION_OF_MYOBLAST_DIFFERENTIATION | GOBP_REGULATION_OF_MYOBLAST_DIFFERENTIATION | 9/1438 | 54/23056 | 0.1666667 | 2.672230 | 3.172958 | 0.0058135 | 0.0236606 | 0.0152106 | RBM24/NOTCH1/BMP4/ZFP36L1/SOX8/MYOCD/SOX9/TNFSF14/TGFB1 | 9 |
| HP_ABNORMALITY_OF_FIBULA_MORPHOLOGY | HP_ABNORMALITY_OF_FIBULA_MORPHOLOGY | HP_ABNORMALITY_OF_FIBULA_MORPHOLOGY | 9/1438 | 54/23056 | 0.1666667 | 2.672230 | 3.172958 | 0.0058135 | 0.0236606 | 0.0152106 | TBX15/FGFR3/GLI3/MET/SHH/EXT1/FGFR2/SOX9/BGN | 9 |
| TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP | 9/1438 | 54/23056 | 0.1666667 | 2.672230 | 3.172958 | 0.0058135 | 0.0236606 | 0.0152106 | TIE1/IFI16/TM4SF1/NPR3/F2RL1/CRHBP/ANGPT1/MYRF/JUP | 9 |
| HP_ABNORMALITY_OF_DENTAL_MORPHOLOGY | HP_ABNORMALITY_OF_DENTAL_MORPHOLOGY | HP_ABNORMALITY_OF_DENTAL_MORPHOLOGY | 28/1438 | 270/23056 | 0.1037037 | 1.662721 | 2.825093 | 0.0058424 | 0.0237712 | 0.0152817 | LAMB3/TGFA/GALNT3/COL3A1/TWIST2/FGFR3/ADAMTS3/FAT4/ADAMTS2/FOXC1/TFAP2A/GJA1/FAM20C/TMEM270/TRPS1/FGFR2/ALX4/C1S/C1R/WNT10B/GLI1/PRKD1/NFKBIA/BMP4/SIX1/FBN1/DLX4/DLX3 | 28 |
| GOBP_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | GOBP_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 22/1438 | 197/23056 | 0.1116751 | 1.790530 | 2.873935 | 0.0058573 | 0.0238178 | 0.0153117 | LDLRAP1/ZC3H12A/PTGS2/IL1B/DAB2/ABLIM3/MICALL2/GLI3/TCAF2/SHH/TCF7L2/BAG3/PRKD1/ANXA2/JUP/TGFB1/EHD2/PRNP/RAC2/MLC1/MSN/TENM1 | 22 |
| HP_AORTIC_ANEURYSM | HP_AORTIC_ANEURYSM | HP_AORTIC_ANEURYSM | 22/1438 | 197/23056 | 0.1116751 | 1.790530 | 2.873935 | 0.0058573 | 0.0238178 | 0.0153117 | MMP23B/HSPG2/PTPN22/TGFB2/COL3A1/COL5A2/TGFBR2/MYLK/TENT5A/TMEM270/TPM2/COL5A1/NOTCH1/MYPN/EFEMP2/ROBO4/FBLN5/FBN1/SMAD6/COL1A1/RIN2/GATA5 | 22 |
| BILD_MYC_ONCOGENIC_SIGNATURE | BILD_MYC_ONCOGENIC_SIGNATURE | BILD_MYC_ONCOGENIC_SIGNATURE | 23/1438 | 209/23056 | 0.1100478 | 1.764439 | 2.863226 | 0.0058687 | 0.0238499 | 0.0153323 | MCOLN2/MTMR11/LAMC2/ATP2B4/SLC12A8/C9/SERPINB1/COL5A1/NRP1/PLAU/NFKB2/AHNAK/ADAMTS15/GPRC5A/EMP1/IRF9/LTBP2/TNFAIP2/RHBDF1/COL1A1/ABCC3/TGM2/RUNX1 | 23 |
| GOBP_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 23/1438 | 209/23056 | 0.1100478 | 1.764439 | 2.863226 | 0.0058687 | 0.0238499 | 0.0153323 | CSF1/RAB7B/ITPKB/CASP8/MITF/LEF1/TLR3/SCIN/HOXA7/INHBA/UBASH3B/NCKAP1L/NFKBIA/ZFP36L1/FOS/FBN1/CSF3/FSTL3/ZFP36/TGFB1/CEBPB/RUNX1/LIF | 23 |
| GOBP_MYELOID_CELL_DEVELOPMENT | GOBP_MYELOID_CELL_DEVELOPMENT | GOBP_MYELOID_CELL_DEVELOPMENT | 11/1438 | 74/23056 | 0.1486486 | 2.383340 | 3.074009 | 0.0059551 | 0.0241561 | 0.0155292 | BCL6/ADGRF5/RHAG/CITED2/FAM20C/NCKAP1L/EPB42/FBN1/ANXA2/SIGLEC15/KLF2 | 11 |
| GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY | 17/1438 | 139/23056 | 0.1223022 | 1.960917 | 2.930681 | 0.0059563 | 0.0241561 | 0.0155292 | MR1/PTPRC/NLRP3/IL1R1/IL1B/F2RL1/HLA-E/RAET1E/IL6/DDX58/KLRD1/KLRC4-KLRK1/STAT6/C3/IL12RB1/TGFB1/NECTIN2 | 17 |
| HP_ABNORMAL_SACRUM_MORPHOLOGY | HP_ABNORMAL_SACRUM_MORPHOLOGY | HP_ABNORMAL_SACRUM_MORPHOLOGY | 17/1438 | 139/23056 | 0.1223022 | 1.960917 | 2.930681 | 0.0059563 | 0.0241561 | 0.0155292 | FUCA1/TWIST2/WNT5A/CD96/FGFRL1/FGFR3/FAT4/RUNX2/BMPER/TMEM270/FGF20/GDF6/COLEC10/ITGA8/FGFR2/TNFRSF1A/MEOX1 | 17 |
| HP_LIMITED_ELBOW_MOVEMENT | HP_LIMITED_ELBOW_MOVEMENT | HP_LIMITED_ELBOW_MOVEMENT | 17/1438 | 139/23056 | 0.1223022 | 1.960917 | 2.930681 | 0.0059563 | 0.0241561 | 0.0155292 | TBX15/COL6A3/FGFR3/TFAP2A/PSMB8/COL12A1/LAMA2/CSGALNACT1/COLEC10/TPM2/FGFR2/ITGA7/FBN1/SMAD6/COL9A3/COL6A2/BGN | 17 |
| HP_VESTIBULAR_DYSFUNCTION | HP_VESTIBULAR_DYSFUNCTION | HP_VESTIBULAR_DYSFUNCTION | 17/1438 | 139/23056 | 0.1223022 | 1.960917 | 2.930681 | 0.0059563 | 0.0241561 | 0.0155292 | PTPN22/COL3A1/NABP1/TECRL/EGF/SH3TC2/CLIC5/TRDN/SLC26A4/TPK1/DKK1/FAS/TNFRSF1A/JUP/CACNA1A/SCN1B/PDGFB | 17 |
| LIU_SOX4_TARGETS_UP | LIU_SOX4_TARGETS_UP | LIU_SOX4_TARGETS_UP | 17/1438 | 139/23056 | 0.1223022 | 1.960917 | 2.930681 | 0.0059563 | 0.0241561 | 0.0155292 | CSF1/ATP2B4/THRB/TMEM158/WWTR1/LEF1/PLK2/HBEGF/TNFRSF21/PDGFA/PRSS23/THBS1/KIFC3/USP43/SOX9/MBP/LIF | 17 |
| PECE_MAMMARY_STEM_CELL_UP | PECE_MAMMARY_STEM_CELL_UP | PECE_MAMMARY_STEM_CELL_UP | 17/1438 | 139/23056 | 0.1223022 | 1.960917 | 2.930681 | 0.0059563 | 0.0241561 | 0.0155292 | S100A2/LAMB3/DDR1/PERP/CLU/CEBPD/BAG3/EPS8L2/KRT8/EHD4/IL4R/MT2A/MT1X/KRT17/SOCS3/APOE/NDP | 17 |
| GOBP_REGULATION_OF_B_CELL_PROLIFERATION | GOBP_REGULATION_OF_B_CELL_PROLIFERATION | GOBP_REGULATION_OF_B_CELL_PROLIFERATION | 10/1438 | 64/23056 | 0.1562500 | 2.505216 | 3.109958 | 0.0059930 | 0.0242761 | 0.0156063 | TNFRSF4/PTPRC/BCL6/MZB1/TNFRSF21/AHR/NCKAP1L/TNFSF13B/CD22/NFATC2 | 10 |
| GOBP_RESPONSE_TO_TYPE_I_INTERFERON | GOBP_RESPONSE_TO_TYPE_I_INTERFERON | GOBP_RESPONSE_TO_TYPE_I_INTERFERON | 10/1438 | 64/23056 | 0.1562500 | 2.505216 | 3.109958 | 0.0059930 | 0.0242761 | 0.0156063 | IKBKE/SP100/WNT5A/STING1/TRIM56/IFITM2/IFITM3/NLRC5/MX1/USP18 | 10 |
| LEE_LIVER_CANCER_MYC_E2F1_DN | LEE_LIVER_CANCER_MYC_E2F1_DN | LEE_LIVER_CANCER_MYC_E2F1_DN | 10/1438 | 64/23056 | 0.1562500 | 2.505216 | 3.109958 | 0.0059930 | 0.0242761 | 0.0156063 | CFH/HSD11B1/KYNU/IL1RAP/TDO2/SFTPD/IGF1/HPD/TRPV2/ELANE | 10 |
| REACTOME_SEMAPHORIN_INTERACTIONS | REACTOME_SEMAPHORIN_INTERACTIONS | REACTOME_SEMAPHORIN_INTERACTIONS | 10/1438 | 64/23056 | 0.1562500 | 2.505216 | 3.109958 | 0.0059930 | 0.0242761 | 0.0156063 | RHOC/PTPRC/SEMA5A/SEMA3A/MET/NRP1/RND1/RRAS/MYL9/MYH9 | 10 |
| GOBP_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 13/1438 | 95/23056 | 0.1368421 | 2.194041 | 3.007738 | 0.0060191 | 0.0243675 | 0.0156650 | S100A13/NMI/SUCNR1/ANXA3/F2RL1/DOCK2/IL4R/LAT/FOXF1/IFI35/MILR1/HMOX1/RAC2 | 13 |
| HP_ABNORMALITY_OF_CORNEAL_STROMA | HP_ABNORMALITY_OF_CORNEAL_STROMA | HP_ABNORMALITY_OF_CORNEAL_STROMA | 13/1438 | 95/23056 | 0.1368421 | 2.194041 | 3.007738 | 0.0060191 | 0.0243675 | 0.0156650 | PTPN22/NLRP3/SLC4A4/TGFBI/FOXC1/PSMB8/PITX3/WT1/MMP2/APOE/COL18A1/IL2RB/NDP | 13 |
| GOBP_AORTA_MORPHOGENESIS | GOBP_AORTA_MORPHOGENESIS | GOBP_AORTA_MORPHOGENESIS | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | TGFB2/COL3A1/MYLK/HES1/NOTCH1/EFEMP2/SIX1 | 7 |
| GOBP_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS | GOBP_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | PPARG/ADTRP/CD36/CES1/CDH13/CD68/APOE | 7 |
| GOBP_POSITIVE_T_CELL_SELECTION | GOBP_POSITIVE_T_CELL_SELECTION | GOBP_POSITIVE_T_CELL_SELECTION | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | PTPRC/ITPKB/DOCK2/IL6/SHH/STAT6/IL12RB1 | 7 |
| GOBP_REGULATION_OF_HORMONE_METABOLIC_PROCESS | GOBP_REGULATION_OF_HORMONE_METABOLIC_PROCESS | GOBP_REGULATION_OF_HORMONE_METABOLIC_PROCESS | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | GFI1/DAB2/BMP6/AKR1C3/TCF7L2/ADM/BMP2 | 7 |
| GOBP_SNRNA_PROCESSING | GOBP_SNRNA_PROCESSING | GOBP_SNRNA_PROCESSING | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | CT45A5/CT45A6/CT45A2/CT45A7/CT45A9/CT45A10/SAGE1 | 7 |
| HAN_JNK_SINGALING_UP | HAN_JNK_SINGALING_UP | HAN_JNK_SINGALING_UP | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | CCN1/GBP4/TGFBI/IRF9/CCL5/RUNX1/USP18 | 7 |
| HP_ABNORMAL_CIRCULATING_FERRITIN_CONCENTRATION | HP_ABNORMAL_CIRCULATING_FERRITIN_CONCENTRATION | HP_ABNORMAL_CIRCULATING_FERRITIN_CONCENTRATION | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | HJV/HFE/STX11/SLC7A7/PIEZO1/KCNN4/BMP2 | 7 |
| HP_CHORIORETINAL_ATROPHY | HP_CHORIORETINAL_ATROPHY | HP_CHORIORETINAL_ATROPHY | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | RPE65/CFH/EFEMP1/CFI/TSPAN12/FZD4/NDP | 7 |
| HP_FATIGABLE_WEAKNESS_OF_SKELETAL_MUSCLES | HP_FATIGABLE_WEAKNESS_OF_SKELETAL_MUSCLES | HP_FATIGABLE_WEAKNESS_OF_SKELETAL_MUSCLES | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | AGRN/CASQ1/DOK7/FLNC/TPM2/MYPN/COL13A1 | 7 |
| HP_PERICARDIAL_EFFUSION | HP_PERICARDIAL_EFFUSION | HP_PERICARDIAL_EFFUSION | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | PTPN14/ADAMTS3/SPP1/FAT4/EPHB4/MAF/PLVAP | 7 |
| KIM_ALL_DISORDERS_CALB1_CORR_DN | KIM_ALL_DISORDERS_CALB1_CORR_DN | KIM_ALL_DISORDERS_CALB1_CORR_DN | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | GFI1/IL1RAP/RREB1/AQP7/ANPEP/GIP/GADD45B | 7 |
| MARZEC_IL2_SIGNALING_DN | MARZEC_IL2_SIGNALING_DN | MARZEC_IL2_SIGNALING_DN | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | PTPRC/PDGFC/CARD6/NT5E/FAS/CASP1/TNFRSF11A | 7 |
| REACTOME_STRIATED_MUSCLE_CONTRACTION | REACTOME_STRIATED_MUSCLE_CONTRACTION | REACTOME_STRIATED_MUSCLE_CONTRACTION | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | DES/TNNC1/TPM2/ACTC1/TPM1/MYH8/MYL4 | 7 |
| YANG_BREAST_CANCER_ESR1_UP | YANG_BREAST_CANCER_ESR1_UP | YANG_BREAST_CANCER_ESR1_UP | 7/1438 | 36/23056 | 0.1944444 | 3.117602 | 3.279420 | 0.0061190 | 0.0246498 | 0.0158465 | MLPH/INPP4B/AHNAK/SCNN1A/KRT18/TNS2/CA12 | 7 |
| GOBP_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION | 8/1438 | 45/23056 | 0.1777778 | 2.850379 | 3.204449 | 0.0061229 | 0.0246498 | 0.0158465 | ERRFI1/ZC3H12A/NLRP3/SERPINB1/TNFAIP3/CARD16/APOA1/IGF1 | 8 |
| GOBP_POSITIVE_REGULATION_OF_MUSCLE_CONTRACTION | GOBP_POSITIVE_REGULATION_OF_MUSCLE_CONTRACTION | GOBP_POSITIVE_REGULATION_OF_MUSCLE_CONTRACTION | 8/1438 | 45/23056 | 0.1777778 | 2.850379 | 3.204449 | 0.0061229 | 0.0246498 | 0.0158465 | EDN2/PTGS2/NPNT/ITGA2/EDN1/CCN2/SPX/MYOCD | 8 |
| GOBP_REGULATION_OF_POLYSACCHARIDE_METABOLIC_PROCESS | GOBP_REGULATION_OF_POLYSACCHARIDE_METABOLIC_PROCESS | GOBP_REGULATION_OF_POLYSACCHARIDE_METABOLIC_PROCESS | 8/1438 | 45/23056 | 0.1777778 | 2.850379 | 3.204449 | 0.0061229 | 0.0246498 | 0.0158465 | EGF/PPP1R3G/HAS2/PPP1R3C/PHLDA2/IGF1/TGFB1/PDGFB | 8 |
| HP_CHORIORETINAL_DEGENERATION | HP_CHORIORETINAL_DEGENERATION | HP_CHORIORETINAL_DEGENERATION | 8/1438 | 45/23056 | 0.1777778 | 2.850379 | 3.204449 | 0.0061229 | 0.0246498 | 0.0158465 | RPE65/CFH/EFEMP1/CFI/TSPAN12/FZD4/ADAMTS18/NDP | 8 |
| LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_DN | 8/1438 | 45/23056 | 0.1777778 | 2.850379 | 3.204449 | 0.0061229 | 0.0246498 | 0.0158465 | LGR6/SEMA3B/SPP1/PHLDA2/CYP19A1/CSF3/COL9A3/SLITRK4 | 8 |
| GOBP_REGULATION_OF_HORMONE_SECRETION | GOBP_REGULATION_OF_HORMONE_SECRETION | GOBP_REGULATION_OF_HORMONE_SECRETION | 25/1438 | 234/23056 | 0.1068376 | 1.712968 | 2.827192 | 0.0061263 | 0.0246562 | 0.0158506 | C1QTNF12/AGT/IL1B/PPARG/FOXL2/SPP1/DAB2/CRHBP/BMP6/EDN1/HFE/GJA1/IL6/INHBA/ADCY8/ANXA1/ALOX5/TCF7L2/KCNA5/CYP19A1/CCL5/GIP/C1QTNF1/IL11/LIF | 25 |
| BROWNE_HCMV_INFECTION_8HR_UP | BROWNE_HCMV_INFECTION_8HR_UP | BROWNE_HCMV_INFECTION_8HR_UP | 14/1438 | 106/23056 | 0.1320755 | 2.117616 | 2.974463 | 0.0061341 | 0.0246587 | 0.0158522 | PLA2G4A/GALNT3/FGF18/COL21A1/SOD2/TLL2/PLAAT4/FOS/ABCA6/ELANE/ICAM1/APOE/MX2/SSX2 | 14 |
| HP_RED_EYE | HP_RED_EYE | HP_RED_EYE | 14/1438 | 106/23056 | 0.1320755 | 2.117616 | 2.974463 | 0.0061341 | 0.0246587 | 0.0158522 | NLRP3/COL7A1/FGFR3/TGFBI/PSMB8/PSMB9/STX11/SAMD9/GSN/FAS/FGFR2/MMP1/TNFRSF1A/FBN1 | 14 |
| REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS | REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS | REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS | 14/1438 | 106/23056 | 0.1320755 | 2.117616 | 2.974463 | 0.0061341 | 0.0246587 | 0.0158522 | FMO3/CYP26B1/AADAC/AHRR/CYP39A1/AHR/PTGS1/CYP26A1/CYP46A1/CYP19A1/CES1/CYP4F11/PTGIS/CYP24A1 | 14 |
| REACTOME_STIMULI_SENSING_CHANNELS | REACTOME_STIMULI_SENSING_CHANNELS | REACTOME_STIMULI_SENSING_CHANNELS | 14/1438 | 106/23056 | 0.1320755 | 2.117616 | 2.974463 | 0.0061341 | 0.0246587 | 0.0158522 | MCOLN2/CASQ1/TRPM8/TRPC3/TRDN/ASPH/TRPA1/TRPM6/SCNN1A/BEST3/TPCN1/TRPC4/MLKL/TRPV2 | 14 |
| GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | GOBP_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY | 15/1438 | 117/23056 | 0.1282051 | 2.055562 | 2.952184 | 0.0061469 | 0.0247029 | 0.0158807 | MR1/PTPRC/NLRP3/IL1R1/IL1B/HLA-E/RAET1E/IL6/KLRD1/KLRC4-KLRK1/STAT6/C3/IL12RB1/TGFB1/NECTIN2 | 15 |
| HP_ABNORMALITY_OF_THE_HELIX | HP_ABNORMALITY_OF_THE_HELIX | HP_ABNORMALITY_OF_THE_HELIX | 18/1438 | 151/23056 | 0.1192053 | 1.911264 | 2.897488 | 0.0061989 | 0.0249044 | 0.0160102 | HSPG2/FN1/FGFR3/RREB1/DSP/TFAP2A/EDN1/HOXA2/FOXP2/FGFR2/DACT1/FBN1/SALL1/JUP/RRAS/BMP2/NDP/GPC4 | 18 |
| HP_INFLAMMATORY_ABNORMALITY_OF_THE_EYE | HP_INFLAMMATORY_ABNORMALITY_OF_THE_EYE | HP_INFLAMMATORY_ABNORMALITY_OF_THE_EYE | 22/1438 | 198/23056 | 0.1111111 | 1.781487 | 2.848323 | 0.0062126 | 0.0249523 | 0.0160410 | PTPN22/NLRP3/CASP10/COL7A1/FGFR3/PSMB8/PSMB9/TNFAIP3/STX11/IL6/SAMD9/GSN/FAS/FGFR2/BIRC3/MMP1/TNFRSF1A/FBN1/APOE/IL2RB/COL4A6/COL4A5 | 22 |
| GOBP_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 12/1438 | 85/23056 | 0.1411765 | 2.263536 | 3.009965 | 0.0063508 | 0.0254848 | 0.0163833 | CCN1/PTGS2/IL1A/IL1B/DAB2/BMP6/ADGRF5/ANXA1/ADM/RAB38/APOA1/APOE | 12 |
| GOBP_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | GOBP_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | GOBP_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS | 12/1438 | 85/23056 | 0.1411765 | 2.263536 | 3.009965 | 0.0063508 | 0.0254848 | 0.0163833 | WNT5A/CITED2/INHBA/SEMA3A/STRA8/SHH/PLAT/ZFPM2/WT1/EDNRB/BNC1/SOX9 | 12 |
| GOBP_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION | GOBP_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION | GOBP_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION | 12/1438 | 85/23056 | 0.1411765 | 2.263536 | 3.009965 | 0.0063508 | 0.0254848 | 0.0163833 | WNT5A/EGF/VEGFC/GLI3/PTPRZ1/PTN/SHH/NOTCH1/PITX3/GLI1/FOXO1/LHX1 | 12 |
| WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | 17/1438 | 140/23056 | 0.1214286 | 1.946910 | 2.898396 | 0.0063967 | 0.0256614 | 0.0164968 | GALNT3/ITGA6/IRAK2/RASSF6/PLAC8/MYO10/IQGAP2/ELL2/PERP/EPHB4/SH2D4A/PHLDA2/SYTL2/NQO1/ABCC3/LLGL2/GGT1 | 17 |
| GOBP_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | GOBP_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | GOBP_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 24/1438 | 223/23056 | 0.1076233 | 1.725566 | 2.808031 | 0.0065306 | 0.0261911 | 0.0168374 | ZC3H12A/PTGS2/PTPN14/IL1B/SP100/SH3TC2/ABLIM3/MICALL2/GLI3/CD36/MDFIC/TCAF2/SHH/ANGPT1/TCF7L2/BAG3/LCP1/PRKD1/BMP4/JUP/TGFB1/PRNP/RAC2/TENM1 | 24 |
| HP_ABNORMAL_MENINGEAL_MORPHOLOGY | HP_ABNORMAL_MENINGEAL_MORPHOLOGY | HP_ABNORMAL_MENINGEAL_MORPHOLOGY | 16/1438 | 129/23056 | 0.1240310 | 1.988636 | 2.904103 | 0.0065515 | 0.0262596 | 0.0168814 | PTCH2/TGFB2/TGFBR2/MYLK/RREB1/BMPER/GLI3/SHH/GAS1/FGFR2/ALX4/GRIP1/FREM2/ZIC2/DACT1/FBN1 | 16 |
| REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE | REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE | REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE | 16/1438 | 129/23056 | 0.1240310 | 1.988636 | 2.904103 | 0.0065515 | 0.0262596 | 0.0168814 | TCHH/SPRR2F/DSP/PERP/KRT80/KRT7/KRT4/KRT79/KRT8/KRT18/KRT13/KRT15/KRT19/KRT17/JUP/DSG2 | 16 |
| GOBP_CELL_KILLING | GOBP_CELL_KILLING | GOBP_CELL_KILLING | 21/1438 | 187/23056 | 0.1122995 | 1.800540 | 2.834879 | 0.0065608 | 0.0262781 | 0.0168933 | MR1/CFH/PTPRC/TGFB2/CXCL6/IL7R/C9/F2RL1/HLA-E/MICA/RAET1E/NLRP6/KLRD1/KLRC4-KLRK1/NCKAP1L/ELANE/C3/ICAM1/IL12RB1/NECTIN2/IL11 | 21 |
| HP_FINGER_SYNDACTYLY | HP_FINGER_SYNDACTYLY | HP_FINGER_SYNDACTYLY | 21/1438 | 187/23056 | 0.1122995 | 1.800540 | 2.834879 | 0.0065608 | 0.0262781 | 0.0168933 | WNT5A/FGFR3/ADAMTS3/FAT4/SEMA5A/DSP/GJA1/GLI3/SHH/NOTCH1/FGFR2/WNT10B/GRIP1/FREM2/BMP4/SALL1/JUP/NOG/ITGB4/PIEZO2/GPC4 | 21 |
| GOBP_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM | GOBP_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM | GOBP_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM | 13/1438 | 96/23056 | 0.1354167 | 2.171187 | 2.965720 | 0.0065749 | 0.0262781 | 0.0168933 | WNT5A/PRICKLE2/DAB2/RSPO3/FZD1/FZD6/CTHRC1/DKK1/DACT1/FOXF1/CELSR1/MSN/GPC4 | 13 |
| GOBP_ALCOHOL_CATABOLIC_PROCESS | GOBP_ALCOHOL_CATABOLIC_PROCESS | GOBP_ALCOHOL_CATABOLIC_PROCESS | 9/1438 | 55/23056 | 0.1636364 | 2.623644 | 3.109231 | 0.0065751 | 0.0262781 | 0.0168933 | SULT1E1/INPP4B/CYP39A1/SYNJ2/AKR1B10/AKR1C3/ALDH3B1/CYP46A1/APOE | 9 |
| LAU_APOPTOSIS_CDKN2A_UP | LAU_APOPTOSIS_CDKN2A_UP | LAU_APOPTOSIS_CDKN2A_UP | 9/1438 | 55/23056 | 0.1636364 | 2.623644 | 3.109231 | 0.0065751 | 0.0262781 | 0.0168933 | CASP8/TNFAIP3/CLU/FAS/CASP1/NFKBIA/TNFRSF12A/TNFSF9/CARD10 | 9 |
| GOBP_POLYSACCHARIDE_BIOSYNTHETIC_PROCESS | GOBP_POLYSACCHARIDE_BIOSYNTHETIC_PROCESS | GOBP_POLYSACCHARIDE_BIOSYNTHETIC_PROCESS | 11/1438 | 75/23056 | 0.1466667 | 2.351562 | 3.023685 | 0.0065952 | 0.0262781 | 0.0168933 | EGF/PPP1R3G/CSGALNACT1/EXT1/HAS2/PPP1R3C/IGF1/B3GNT3/TGFB1/HAS1/PDGFB | 11 |
| GOBP_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | GOBP_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | GOBP_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | 11/1438 | 75/23056 | 0.1466667 | 2.351562 | 3.023685 | 0.0065952 | 0.0262781 | 0.0168933 | TNFRSF4/PTPRC/BCL6/MZB1/HLA-E/IL6/STAT6/IL4R/IL27RA/CD22/TGFB1 | 11 |
| HP_ABNORMAL_EPIDERMAL_MORPHOLOGY | HP_ABNORMAL_EPIDERMAL_MORPHOLOGY | HP_ABNORMAL_EPIDERMAL_MORPHOLOGY | 11/1438 | 75/23056 | 0.1466667 | 2.351562 | 3.023685 | 0.0065952 | 0.0262781 | 0.0168933 | CLDN1/IL7R/OSMR/DSP/GJA1/PERP/COL14A1/KRT13/JUP/SERPINB7/SERPINB8 | 11 |
| BIOCARTA_COMP_PATHWAY | BIOCARTA_COMP_PATHWAY | BIOCARTA_COMP_PATHWAY | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | C9/MBL2/C1S/C1R/C3 | 5 |
| GOBP_BASE_CONVERSION_OR_SUBSTITUTION_EDITING | GOBP_BASE_CONVERSION_OR_SUBSTITUTION_EDITING | GOBP_BASE_CONVERSION_OR_SUBSTITUTION_EDITING | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | RBM47/ADAD1/APOBEC3A/APOBEC3G/APOBEC3H | 5 |
| GOBP_ENAMEL_MINERALIZATION | GOBP_ENAMEL_MINERALIZATION | GOBP_ENAMEL_MINERALIZATION | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | ITGB6/AMTN/ENAM/FAM20C/SLC24A4 | 5 |
| GOBP_GAMMA_DELTA_T_CELL_ACTIVATION | GOBP_GAMMA_DELTA_T_CELL_ACTIVATION | GOBP_GAMMA_DELTA_T_CELL_ACTIVATION | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | PTPRC/LEF1/MICA/MICB/NCKAP1L | 5 |
| GOBP_INTERLEUKIN_13_PRODUCTION | GOBP_INTERLEUKIN_13_PRODUCTION | GOBP_INTERLEUKIN_13_PRODUCTION | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | IL1RAP/LEF1/TSLP/HLA-E/TNFRSF21 | 5 |
| GOBP_MESENCHYMAL_TO_EPITHELIAL_TRANSITION | GOBP_MESENCHYMAL_TO_EPITHELIAL_TRANSITION | GOBP_MESENCHYMAL_TO_EPITHELIAL_TRANSITION | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | GDNF/WT1/BMP4/SALL1/LIF | 5 |
| GOBP_MYELOID_DENDRITIC_CELL_DIFFERENTIATION | GOBP_MYELOID_DENDRITIC_CELL_DIFFERENTIATION | GOBP_MYELOID_DENDRITIC_CELL_DIFFERENTIATION | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | ITGB6/TGFBR2/CSF2/ITGB8/RELB | 5 |
| GOBP_NEGATIVE_REGULATION_OF_PROGRAMMED_NECROTIC_CELL_DEATH | GOBP_NEGATIVE_REGULATION_OF_PROGRAMMED_NECROTIC_CELL_DEATH | GOBP_NEGATIVE_REGULATION_OF_PROGRAMMED_NECROTIC_CELL_DEATH | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | CASP8/CAV1/BIRC3/YBX3/NUPR1 | 5 |
| GOBP_NEGATIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | IL7R/IDO1/ST3GAL1/BMP4/CCL5 | 5 |
| GOBP_REGULATION_OF_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_SKELETAL_MUSCLE_CELL_DIFFERENTIATION | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | CYP26B1/RBM24/SIX1/SIX4/MYOCD | 5 |
| GOBP_SINGLE_STRANDED_VIRAL_RNA_REPLICATION_VIA_DOUBLE_STRANDED_DNA_INTERMEDIATE | GOBP_SINGLE_STRANDED_VIRAL_RNA_REPLICATION_VIA_DOUBLE_STRANDED_DNA_INTERMEDIATE | GOBP_SINGLE_STRANDED_VIRAL_RNA_REPLICATION_VIA_DOUBLE_STRANDED_DNA_INTERMEDIATE | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | CXCL8/HMGA2/APOBEC3A/APOBEC3G/APOBEC3H | 5 |
| HP_ABNORMAL_RIGHT_VENTRICULAR_FUNCTION | HP_ABNORMAL_RIGHT_VENTRICULAR_FUNCTION | HP_ABNORMAL_RIGHT_VENTRICULAR_FUNCTION | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | WNT5A/SLC34A2/CITED2/ACTC1/GATA6 | 5 |
| HP_CONGENITAL_MUSCULAR_DYSTROPHY | HP_CONGENITAL_MUSCULAR_DYSTROPHY | HP_CONGENITAL_MUSCULAR_DYSTROPHY | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | COL6A3/COL12A1/LAMA2/ITGA7/COL6A2 | 5 |
| LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK | LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK | LIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | VCAM1/NRP2/ACKR3/PLA2G7/HTRA1 | 5 |
| MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP | MASRI_RESISTANCE_TO_TAMOXIFEN_AND_AROMATASE_INHIBITORS_UP | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | CYP26B1/GJA1/MYBL1/SULF1/PGR | 5 |
| REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | CHSY3/CSGALNACT1/CSPG4/CHST7/BGN | 5 |
| WP_HYPERTROPHY_MODEL | WP_HYPERTROPHY_MODEL | WP_HYPERTROPHY_MODEL | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | CCN1/IL1R1/IL1A/HBEGF/ANKRD1 | 5 |
| YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN | 5/1438 | 20/23056 | 0.2500000 | 4.008345 | 3.471309 | 0.0066059 | 0.0262781 | 0.0168933 | FN1/FST/GJA1/ALDH1A2/DSG2 | 5 |
| HP_FUNCTIONAL_ABNORMALITY_OF_THE_MIDDLE_EAR | HP_FUNCTIONAL_ABNORMALITY_OF_THE_MIDDLE_EAR | HP_FUNCTIONAL_ABNORMALITY_OF_THE_MIDDLE_EAR | 38/1438 | 400/23056 | 0.0950000 | 1.523171 | 2.722302 | 0.0066100 | 0.0262868 | 0.0168989 | MMP23B/HSPG2/RPE65/PTPN22/PRRX1/CFAP221/FGFRL1/FGFR3/ADAMTS3/SGMS2/FAT4/DNAH5/MCIDAS/CCNO/RREB1/TFAP2A/EDN1/TENT5A/GJA1/FAM20C/AHR/HOXA2/GDF6/TRPS1/EXT1/FGFR2/CREB3L1/GRIP1/FREM2/BMP4/SIX1/FBN1/MEOX1/DLX4/NOG/TNFRSF11A/BMP2/ARSL | 38 |
| GOBP_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | GOBP_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | GOBP_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | 14/1438 | 107/23056 | 0.1308411 | 2.097825 | 2.935604 | 0.0066634 | 0.0264693 | 0.0170162 | PTGS2/ATP2B4/WNT5A/IL6/CAV1/ANGPT1/IFNE/CD44/PRKD1/CSF3/TGFB1/IL11/LIF/TENM1 | 14 |
| CHIN_BREAST_CANCER_COPY_NUMBER_UP | CHIN_BREAST_CANCER_COPY_NUMBER_UP | CHIN_BREAST_CANCER_COPY_NUMBER_UP | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | LAMC2/PTGS2/TGFB2/EXT1/LRRC32/CYP24A1 | 6 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_KILLING | GOBP_NEGATIVE_REGULATION_OF_CELL_KILLING | GOBP_NEGATIVE_REGULATION_OF_CELL_KILLING | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | PTPRC/IL7R/HLA-E/MICA/KLRD1/NCKAP1L | 6 |
| GOBP_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | SERPINE2/SERPINE1/GAS1/CARD16/THBS1/PRNP | 6 |
| GOBP_POSITIVE_REGULATION_OF_PROTEIN_MATURATION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_MATURATION | GOBP_POSITIVE_REGULATION_OF_PROTEIN_MATURATION | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | S100A10/NKD2/GSN/MMP14/ANXA2/MYH9 | 6 |
| GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | DSP/TBX18/CAV1/HCN4/JUP/DSG2 | 6 |
| GOBP_REGULATION_OF_PLATELET_AGGREGATION | GOBP_REGULATION_OF_PLATELET_AGGREGATION | GOBP_REGULATION_OF_PLATELET_AGGREGATION | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | SERPINE2/IL6/UBASH3B/ADAMTS18/C1QTNF1/EMILIN2 | 6 |
| GOBP_RIG_I_SIGNALING_PATHWAY | GOBP_RIG_I_SIGNALING_PATHWAY | GOBP_RIG_I_SIGNALING_PATHWAY | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | DDX60/DDX58/BIRC3/OASL/RNF135/DHX58 | 6 |
| HP_MORPHOLOGICAL_ABNORMALITY_OF_THE_MIDDLE_EAR | HP_MORPHOLOGICAL_ABNORMALITY_OF_THE_MIDDLE_EAR | HP_MORPHOLOGICAL_ABNORMALITY_OF_THE_MIDDLE_EAR | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | TFAP2A/GDF6/SIX1/COL1A1/NOG/SIX5 | 6 |
| HP_SYRINGOMYELIA | HP_SYRINGOMYELIA | HP_SYRINGOMYELIA | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | RUNX2/TENT5A/EXT1/DKK1/HMGA2/FOXF1 | 6 |
| PID_TCR_CALCIUM_PATHWAY | PID_TCR_CALCIUM_PATHWAY | PID_TCR_CALCIUM_PATHWAY | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | PTGS2/CSF2/RCAN2/FOSL1/FOS/NFATC2 | 6 |
| REACTOME_ENDOGENOUS_STEROLS | REACTOME_ENDOGENOUS_STEROLS | REACTOME_ENDOGENOUS_STEROLS | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | AHRR/CYP39A1/AHR/CYP46A1/CYP19A1/PTGIS | 6 |
| WILENSKY_RESPONSE_TO_DARAPLADIB | WILENSKY_RESPONSE_TO_DARAPLADIB | WILENSKY_RESPONSE_TO_DARAPLADIB | 6/1438 | 28/23056 | 0.2142857 | 3.435724 | 3.326084 | 0.0066940 | 0.0264693 | 0.0170162 | CTSS/IL1A/PLA2G7/CD68/CCL5/HMOX1 | 6 |
| GOBP_EXCRETION | GOBP_EXCRETION | GOBP_EXCRETION | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | AGT/CLDN16/ABCG2/EDN1/ATP6V0A4/STC1/SLC22A18/SPX/EDNRB/HMOX1 | 10 |
| GOBP_HORMONE_BIOSYNTHETIC_PROCESS | GOBP_HORMONE_BIOSYNTHETIC_PROCESS | GOBP_HORMONE_BIOSYNTHETIC_PROCESS | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | GFI1/SRD5A2/DAB2/BMP6/HFE/AKR1B15/ADM/DIO2/CYP19A1/BMP2 | 10 |
| GOBP_RESPONSE_TO_ACTIVITY | GOBP_RESPONSE_TO_ACTIVITY | GOBP_RESPONSE_TO_ACTIVITY | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | PERM1/AGT/ITGA2/BMP6/EDN1/SOD2/IL6/TNS2/MMP2/METRNL | 10 |
| HP_OPEN_BITE | HP_OPEN_BITE | HP_OPEN_BITE | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | KCNN3/ITGB6/WNT5A/FGFR3/ENAM/ADAMTS2/RUNX2/TMEM270/FGFR2/BMP2 | 10 |
| LEE_LIVER_CANCER_ACOX1_UP | LEE_LIVER_CANCER_ACOX1_UP | LEE_LIVER_CANCER_ACOX1_UP | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | NIBAN1/SPON2/EDN1/PLAT/FABP4/KRT8/ANXA2/MFGE8/MT2A/NQO1 | 10 |
| LEE_LIVER_CANCER_MYC_TGFA_DN | LEE_LIVER_CANCER_MYC_TGFA_DN | LEE_LIVER_CANCER_MYC_TGFA_DN | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | HSD11B1/KYNU/IL1RAP/ABCG2/TDO2/GPR37/CA3/IGF1/HPD/TRPV2 | 10 |
| PID_LYSOPHOSPHOLIPID_PATHWAY | PID_LYSOPHOSPHOLIPID_PATHWAY | PID_LYSOPHOSPHOLIPID_PATHWAY | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | CXCL8/HBEGF/IL6/TRIP6/ADCY8/PRKD1/NFKBIA/FOS/MMP2/LPAR4 | 10 |
| PID_RB_1PATHWAY | PID_RB_1PATHWAY | PID_RB_1PATHWAY | 10/1438 | 65/23056 | 0.1538462 | 2.466674 | 3.053975 | 0.0066964 | 0.0264693 | 0.0170162 | TGFB2/PPARG/MITF/CSF2/RUNX2/MET/CEBPD/SFTPD/CKM/CEBPB | 10 |
| ZHENG_GLIOBLASTOMA_PLASTICITY_UP | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | 26/1438 | 248/23056 | 0.1048387 | 1.680919 | 2.780557 | 0.0067075 | 0.0265057 | 0.0170396 | CCN1/ALDH1L1/SPP1/HFE/IER3/PLA2G7/ADGRG6/BMPER/CD36/SEMA3A/CLU/ASPH/CA3/FZD6/ANGPT1/FBXO32/EDNRB/MFGE8/NUPR1/MT1X/MBP/SCN1B/SDC4/CSDC2/COL4A6/IL13RA1 | 26 |
| HP_WEIGHT_LOSS | HP_WEIGHT_LOSS | HP_WEIGHT_LOSS | 30/1438 | 298/23056 | 0.1006711 | 1.614099 | 2.751905 | 0.0067458 | 0.0266492 | 0.0171319 | ECE1/HSPG2/PTPN22/NABP1/TGFBR2/BCL6/SLC34A2/GDNF/HFE/GJA1/IL6/SEMA3C/SEMA3D/TPM2/FAS/WT1/BIRC3/SCNN1A/ITGA7/STAT6/EDNRB/RHBDF2/TGFB1/PRNP/CYP24A1/RUNX1/IL2RB/NDP/COL4A6/COL4A5 | 30 |
| GOBP_SIGNAL_RELEASE | GOBP_SIGNAL_RELEASE | GOBP_SIGNAL_RELEASE | 42/1438 | 453/23056 | 0.0927152 | 1.486538 | 2.697351 | 0.0067822 | 0.0266897 | 0.0171579 | C1QTNF12/ILDR2/PLA2G4A/AGT/IL1A/IL1B/PPARG/FOXL2/SUCNR1/SPP1/GDNF/DAB2/FOXD1/F2RL1/CRHBP/SNCAIP/BMP6/EDN1/HFE/GJA1/STX11/IL6/INHBA/CADPS2/FGF20/ADCY8/ANXA1/PCSK5/ALOX5/TCF7L2/ADM/SYT12/FZD4/KCNA5/EDNRB/CYP19A1/CCL5/GIP/C1QTNF1/TNFRSF11A/IL11/LIF | 42 |
| GOBP_ACTIN_FILAMENT_BUNDLE_ORGANIZATION | GOBP_ACTIN_FILAMENT_BUNDLE_ORGANIZATION | GOBP_ACTIN_FILAMENT_BUNDLE_ORGANIZATION | 19/1438 | 164/23056 | 0.1158537 | 1.857526 | 2.842376 | 0.0068009 | 0.0266897 | 0.0171579 | S1PR1/RHOC/S100A10/PHLDB2/ITGB5/CCN2/MET/ZYX/ARHGEF5/AIF1L/NRP1/SYNPO2L/APOA1/EPS8/LCP1/CGNL1/TPM1/SDC4/PLS3 | 19 |
| LIU_CMYB_TARGETS_UP | LIU_CMYB_TARGETS_UP | LIU_CMYB_TARGETS_UP | 19/1438 | 164/23056 | 0.1158537 | 1.857526 | 2.842376 | 0.0068009 | 0.0266897 | 0.0171579 | ECE1/CRIM1/LYPD1/RBM47/MYO10/TGFBI/CITED2/SH2D4A/CA12/MT2A/MT1X/NQO1/CRISPLD2/TRPV2/ABCC3/SOX9/EMP3/CDC42EP1/SAT1 | 19 |
| BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | 25/1438 | 236/23056 | 0.1059322 | 1.698451 | 2.781561 | 0.0068119 | 0.0266897 | 0.0171579 | IFI16/GPR39/SP100/TM4SF1/STK32B/ARHGAP24/CFI/IQGAP2/GMPR/AKR1B10/PDCD1LG2/AQP3/ANXA1/PCSK5/GSN/DNMBP/PLAAT4/ABCA6/SLC14A1/DOK5/RUNX1/SIM2/GGT1/SAT1/COL4A6 | 25 |
| GOBP_RESPONSE_TO_ALCOHOL | GOBP_RESPONSE_TO_ALCOHOL | GOBP_RESPONSE_TO_ALCOHOL | 25/1438 | 236/23056 | 0.1059322 | 1.698451 | 2.781561 | 0.0068119 | 0.0266897 | 0.0171579 | CDA/VCAM1/CASP8/TGFBR2/CLDN1/SLIT2/CRHBP/SOD2/AHR/INHBA/CA3/ADCY8/AKR1C3/FGFR2/FOSL1/EPS8/FOS/CES1/NQO1/CSF3/CCR7/JUP/KLF2/TGFB1/MLC1 | 25 |
| BIOCARTA_IL10_PATHWAY | BIOCARTA_IL10_PATHWAY | BIOCARTA_IL10_PATHWAY | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | IL1A/IL6/BLVRB/HMOX1 | 4 |
| GOBP_CARDIAC_NEURAL_CREST_CELL_DEVELOPMENT_INVOLVED_IN_OUTFLOW_TRACT_MORPHOGENESIS | GOBP_CARDIAC_NEURAL_CREST_CELL_DEVELOPMENT_INVOLVED_IN_OUTFLOW_TRACT_MORPHOGENESIS | GOBP_CARDIAC_NEURAL_CREST_CELL_DEVELOPMENT_INVOLVED_IN_OUTFLOW_TRACT_MORPHOGENESIS | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | HES1/EDN1/SEMA3C/BMP4 | 4 |
| GOBP_FAT_SOLUBLE_VITAMIN_CATABOLIC_PROCESS | GOBP_FAT_SOLUBLE_VITAMIN_CATABOLIC_PROCESS | GOBP_FAT_SOLUBLE_VITAMIN_CATABOLIC_PROCESS | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | CYP26B1/CYP26A1/CYP4F11/CYP24A1 | 4 |
| GOBP_GLOMERULAR_EPITHELIAL_CELL_DEVELOPMENT | GOBP_GLOMERULAR_EPITHELIAL_CELL_DEVELOPMENT | GOBP_GLOMERULAR_EPITHELIAL_CELL_DEVELOPMENT | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | LAMB2/PODXL/BMP4/MYO1E | 4 |
| GOBP_HYPERSENSITIVITY | GOBP_HYPERSENSITIVITY | GOBP_HYPERSENSITIVITY | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | HLA-E/EXT1/CCR7/C3 | 4 |
| GOBP_NEGATIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | LEF1/YBX3/BMP4/TGFB1 | 4 |
| GOBP_POSITIVE_REGULATION_OF_PSEUDOPODIUM_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_PSEUDOPODIUM_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_PSEUDOPODIUM_ASSEMBLY | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | F2RL1/CCR7/CDC42EP5/CDC42EP1 | 4 |
| GOBP_POSITIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | WNT5A/IDO1/CD274/CCL5 | 4 |
| GOBP_POSITIVE_REGULATION_OF_URINE_VOLUME | GOBP_POSITIVE_REGULATION_OF_URINE_VOLUME | GOBP_POSITIVE_REGULATION_OF_URINE_VOLUME | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | NPR3/EDN1/HAS2/EDNRB | 4 |
| GOBP_REGULATION_OF_NUCLEOTIDE_BINDING_OLIGOMERIZATION_DOMAIN_CONTAINING_SIGNALING_PATHWAY | GOBP_REGULATION_OF_NUCLEOTIDE_BINDING_OLIGOMERIZATION_DOMAIN_CONTAINING_SIGNALING_PATHWAY | GOBP_REGULATION_OF_NUCLEOTIDE_BINDING_OLIGOMERIZATION_DOMAIN_CONTAINING_SIGNALING_PATHWAY | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | PTPN22/TNFAIP3/SLC15A3/BIRC3 | 4 |
| GOBP_REGULATION_OF_SKELETAL_MUSCLE_CELL_PROLIFERATION | GOBP_REGULATION_OF_SKELETAL_MUSCLE_CELL_PROLIFERATION | GOBP_REGULATION_OF_SKELETAL_MUSCLE_CELL_PROLIFERATION | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | SHH/ANGPT1/SIX1/SIX5 | 4 |
| GOMF_CO_RECEPTOR_BINDING | GOMF_CO_RECEPTOR_BINDING | GOMF_CO_RECEPTOR_BINDING | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | HFE/DKK1/BMP4/BMP2 | 4 |
| GOMF_GAMMA_CATENIN_BINDING | GOMF_GAMMA_CATENIN_BINDING | GOMF_GAMMA_CATENIN_BINDING | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | LEF1/PTPRK/TCF7L2/PTPRJ | 4 |
| GOMF_MYOSIN_HEAVY_CHAIN_BINDING | GOMF_MYOSIN_HEAVY_CHAIN_BINDING | GOMF_MYOSIN_HEAVY_CHAIN_BINDING | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | NKD2/MYL4/AXL/MYL9 | 4 |
| HP_ABNORMAL_LEFT_ATRIUM_MORPHOLOGY | HP_ABNORMAL_LEFT_ATRIUM_MORPHOLOGY | HP_ABNORMAL_LEFT_ATRIUM_MORPHOLOGY | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | RARB/FLNC/MYPN/SCN1B | 4 |
| HP_ALOPECIA_TOTALIS | HP_ALOPECIA_TOTALIS | HP_ALOPECIA_TOTALIS | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | DSP/GJA1/NFKB2/JUP | 4 |
| HP_APLASIA_OF_THE_PHALANGES_OF_THE_HAND | HP_APLASIA_OF_THE_PHALANGES_OF_THE_HAND | HP_APLASIA_OF_THE_PHALANGES_OF_THE_HAND | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | FGFR3/GJA1/SHH/FGFR2 | 4 |
| HP_BAND_KERATOPATHY | HP_BAND_KERATOPATHY | HP_BAND_KERATOPATHY | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | PTPN22/SLC4A4/COL18A1/IL2RB | 4 |
| HP_HEMOLYTIC_UREMIC_SYNDROME | HP_HEMOLYTIC_UREMIC_SYNDROME | HP_HEMOLYTIC_UREMIC_SYNDROME | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | CFH/CFI/C3/THBD | 4 |
| HP_LICHENIFICATION | HP_LICHENIFICATION | HP_LICHENIFICATION | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | TNFRSF1B/COL7A1/VEGFC/OSMR | 4 |
| HP_LOWER_LIMB_UNDERGROWTH | HP_LOWER_LIMB_UNDERGROWTH | HP_LOWER_LIMB_UNDERGROWTH | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | FN1/EXT1/PAPSS2/NOG | 4 |
| HP_MYOCARDIAL_FIBROSIS | HP_MYOCARDIAL_FIBROSIS | HP_MYOCARDIAL_FIBROSIS | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | SERPINE1/FLNC/MYPN/JPH2 | 4 |
| INAMURA_LUNG_CANCER_SCC_DN | INAMURA_LUNG_CANCER_SCC_DN | INAMURA_LUNG_CANCER_SCC_DN | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | CAV1/ADAMTS8/VWF/ABCA8 | 4 |
| MARTINELLI_IMMATURE_NEUTROPHIL_DN | MARTINELLI_IMMATURE_NEUTROPHIL_DN | MARTINELLI_IMMATURE_NEUTROPHIL_DN | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | FCGR2A/CXCL8/SOD2/SEMA3C | 4 |
| MIKKELSEN_NPC_ICP_WITH_H3K27ME3 | MIKKELSEN_NPC_ICP_WITH_H3K27ME3 | MIKKELSEN_NPC_ICP_WITH_H3K27ME3 | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | MLPH/HLA-E/HOXB13/TTLL6 | 4 |
| NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_DN | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | IKBKE/CASP10/TNFAIP3/STAT6 | 4 |
| REACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING | REACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING | REACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | EREG/BTC/EGF/HBEGF | 4 |
| REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | FGF5/FGF18/FGF20/FGFR2 | 4 |
| REACTOME_NF_KB_ACTIVATION_THROUGH_FADD_RIP_1_PATHWAY_MEDIATED_BY_CASPASE_8_AND_10 | REACTOME_NF_KB_ACTIVATION_THROUGH_FADD_RIP_1_PATHWAY_MEDIATED_BY_CASPASE_8_AND_10 | REACTOME_NF_KB_ACTIVATION_THROUGH_FADD_RIP_1_PATHWAY_MEDIATED_BY_CASPASE_8_AND_10 | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | CASP10/CASP8/DDX58/RNF135 | 4 |
| REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_TESTIS_DIFFERENTIATION | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | FOXL2/ZFPM2/WT1/SOX9 | 4 |
| SHI_SPARC_TARGETS_DN | SHI_SPARC_TARGETS_DN | SHI_SPARC_TARGETS_DN | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | SEMA3B/SPARC/AHR/MAP3K8 | 4 |
| WP_EDA_SIGNALING_IN_HAIR_FOLLICLE_DEVELOPMENT | WP_EDA_SIGNALING_IN_HAIR_FOLLICLE_DEVELOPMENT | WP_EDA_SIGNALING_IN_HAIR_FOLLICLE_DEVELOPMENT | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | SHH/DKK1/GLI1/RELB | 4 |
| WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_PUBERTY_STAGE_2_OF_4 | WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_PUBERTY_STAGE_2_OF_4 | WP_MAMMARY_GLAND_DEVELOPMENT_PATHWAY_PUBERTY_STAGE_2_OF_4 | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | FN1/EGF/FOSL1/PGR | 4 |
| WP_TRANSCRIPTIONAL_CASCADE_REGULATING_ADIPOGENESIS | WP_TRANSCRIPTIONAL_CASCADE_REGULATING_ADIPOGENESIS | WP_TRANSCRIPTIONAL_CASCADE_REGULATING_ADIPOGENESIS | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | PPARG/CEBPD/KLF2/CEBPB | 4 |
| WU_HBX_TARGETS_3_DN | WU_HBX_TARGETS_3_DN | WU_HBX_TARGETS_3_DN | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | IL6/WT1/EBI3/TGFB1 | 4 |
| YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | YAGUE_PRETUMOR_DRUG_RESISTANCE_DN | 4/1438 | 13/23056 | 0.3076923 | 4.933348 | 3.658632 | 0.0068357 | 0.0266897 | 0.0171579 | COL8A1/RREB1/LTBP2/MMP2 | 4 |
| WP_APOPTOSIS | WP_APOPTOSIS | WP_APOPTOSIS | 12/1438 | 86/23056 | 0.1395349 | 2.237216 | 2.964616 | 0.0069727 | 0.0272168 | 0.0174968 | TNFRSF1B/CASP10/CASP8/TNFRSF21/TRAF1/FAS/BIRC3/CASP4/CASP1/TNFRSF1A/IGF1/NFKBIA | 12 |
| HALLMARK_GLYCOLYSIS | HALLMARK_GLYCOLYSIS | HALLMARK_GLYCOLYSIS | 22/1438 | 200/23056 | 0.1100000 | 1.763672 | 2.797537 | 0.0069765 | 0.0272239 | 0.0175013 | AGRN/ELF3/TGFA/LCT/TGFBI/IER3/TPBG/NT5E/CITED2/MET/STC1/EXT1/B4GALT1/COL5A1/CD44/PYGL/SOX9/SLC16A3/B3GNT3/KDELR3/IL13RA1/GPC4 | 22 |
| GOBP_GENITALIA_DEVELOPMENT | GOBP_GENITALIA_DEVELOPMENT | GOBP_GENITALIA_DEVELOPMENT | 8/1438 | 46/23056 | 0.1739130 | 2.788414 | 3.131431 | 0.0070158 | 0.0273459 | 0.0175798 | SRD5A2/WNT5A/BMP6/SHH/WT1/CYP19A1/LHX1/AXL | 8 |
| GOBP_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | GOBP_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | GOBP_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | 8/1438 | 46/23056 | 0.1739130 | 2.788414 | 3.131431 | 0.0070158 | 0.0273459 | 0.0175798 | LEF1/GJA1/SHH/YBX3/WNT10B/BMP4/TGFB1/JPH2 | 8 |
| HP_RETICULOCYTOSIS | HP_RETICULOCYTOSIS | HP_RETICULOCYTOSIS | 8/1438 | 46/23056 | 0.1739130 | 2.788414 | 3.131431 | 0.0070158 | 0.0273459 | 0.0175798 | CFH/GYPC/CASP10/RHAG/FAS/EPB42/PIEZO1/KCNN4 | 8 |
| NAKAJIMA_MAST_CELL | NAKAJIMA_MAST_CELL | NAKAJIMA_MAST_CELL | 8/1438 | 46/23056 | 0.1739130 | 2.788414 | 3.131431 | 0.0070158 | 0.0273459 | 0.0175798 | CAPG/GPNMB/CLU/PLAT/PHLDA2/VWA5A/CAVIN1/GDF15 | 8 |
| GOBP_LEUKOCYTE_MEDIATED_CYTOTOXICITY | GOBP_LEUKOCYTE_MEDIATED_CYTOTOXICITY | GOBP_LEUKOCYTE_MEDIATED_CYTOTOXICITY | 16/1438 | 130/23056 | 0.1230769 | 1.973339 | 2.870291 | 0.0070507 | 0.0274743 | 0.0176623 | MR1/PTPRC/CXCL6/IL7R/F2RL1/HLA-E/MICA/RAET1E/NLRP6/KLRD1/KLRC4-KLRK1/NCKAP1L/ELANE/ICAM1/IL12RB1/NECTIN2 | 16 |
| GOBP_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | GOBP_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | GOBP_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | 18/1438 | 153/23056 | 0.1176471 | 1.886280 | 2.836774 | 0.0070922 | 0.0276124 | 0.0177511 | AGT/IL1A/SLC12A8/SLC4A4/SLC12A7/EDN1/PDK4/SLC26A4/ATP6V0A4/EXT1/CCKBR/RAB38/KCNA5/SCNN1A/SPX/EDNRB/RAB20/KCNJ2 | 18 |
| HP_ABNORMALITY_OF_FEMALE_EXTERNAL_GENITALIA | HP_ABNORMALITY_OF_FEMALE_EXTERNAL_GENITALIA | HP_ABNORMALITY_OF_FEMALE_EXTERNAL_GENITALIA | 18/1438 | 153/23056 | 0.1176471 | 1.886280 | 2.836774 | 0.0070922 | 0.0276124 | 0.0177511 | MMP23B/HSPG2/TBX15/TWIST2/PPARG/WNT5A/CD96/SIM1/CAV1/ZFPM2/FGFR2/WT1/GRIP1/FREM2/FOS/CYP19A1/CAVIN1/SOX9 | 18 |
| HP_PREMATURELY_AGED_APPEARANCE | HP_PREMATURELY_AGED_APPEARANCE | HP_PREMATURELY_AGED_APPEARANCE | 18/1438 | 153/23056 | 0.1176471 | 1.886280 | 2.836774 | 0.0070922 | 0.0276124 | 0.0177511 | PTPN22/COL3A1/COL5A2/TWIST2/MITF/FGFR3/ADAMTS2/TFAP2A/PSMB8/TMEM270/COL5A1/FAS/FGFR2/C1R/EDNRB/FBLN5/FBN1/COL1A1 | 18 |
| GOBP_C21_STEROID_HORMONE_METABOLIC_PROCESS | GOBP_C21_STEROID_HORMONE_METABOLIC_PROCESS | GOBP_C21_STEROID_HORMONE_METABOLIC_PROCESS | 7/1438 | 37/23056 | 0.1891892 | 3.033342 | 3.192437 | 0.0071489 | 0.0277781 | 0.0178576 | DAB2/BMP6/AKR1C3/ADM/EDNRB/CYP46A1/BMP2 | 7 |
| GOBP_DOPAMINERGIC_NEURON_DIFFERENTIATION | GOBP_DOPAMINERGIC_NEURON_DIFFERENTIATION | GOBP_DOPAMINERGIC_NEURON_DIFFERENTIATION | 7/1438 | 37/23056 | 0.1891892 | 3.033342 | 3.192437 | 0.0071489 | 0.0277781 | 0.0178576 | WNT5A/FZD1/SHH/FGF20/RSPO2/DKK1/PITX3 | 7 |
| GOBP_ERYTHROCYTE_DEVELOPMENT | GOBP_ERYTHROCYTE_DEVELOPMENT | GOBP_ERYTHROCYTE_DEVELOPMENT | 7/1438 | 37/23056 | 0.1891892 | 3.033342 | 3.192437 | 0.0071489 | 0.0277781 | 0.0178576 | BCL6/ADGRF5/RHAG/CITED2/NCKAP1L/EPB42/KLF2 | 7 |
| GOBP_LENS_FIBER_CELL_DIFFERENTIATION | GOBP_LENS_FIBER_CELL_DIFFERENTIATION | GOBP_LENS_FIBER_CELL_DIFFERENTIATION | 7/1438 | 37/23056 | 0.1891892 | 3.033342 | 3.192437 | 0.0071489 | 0.0277781 | 0.0178576 | EPHA2/SLC7A11/PITX3/PLAAT3/MAF/BFSP1/WNT7B | 7 |
| HP_ABSENT_FINGERNAIL | HP_ABSENT_FINGERNAIL | HP_ABSENT_FINGERNAIL | 7/1438 | 37/23056 | 0.1891892 | 3.033342 | 3.192437 | 0.0071489 | 0.0277781 | 0.0178576 | KCNN3/COL7A1/DSP/NOTCH1/JUP/NOG/SCN1B | 7 |
| HP_CHRONIC_LUNG_DISEASE | HP_CHRONIC_LUNG_DISEASE | HP_CHRONIC_LUNG_DISEASE | 7/1438 | 37/23056 | 0.1891892 | 3.033342 | 3.192437 | 0.0071489 | 0.0277781 | 0.0178576 | FCGR2A/SHH/GAS1/SERPINH1/ZIC2/LAT/TGFB1 | 7 |
| PID_IL23_PATHWAY | PID_IL23_PATHWAY | PID_IL23_PATHWAY | 7/1438 | 37/23056 | 0.1891892 | 3.033342 | 3.192437 | 0.0071489 | 0.0277781 | 0.0178576 | IL1B/CXCL1/IL6/NFKBIA/ITGA3/SOCS3/IL12RB1 | 7 |
| GAVIN_FOXP3_TARGETS_CLUSTER_T4 | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | 13/1438 | 97/23056 | 0.1340206 | 2.148804 | 2.924215 | 0.0071706 | 0.0278388 | 0.0178966 | TNFRSF9/NIBAN1/CAPG/ITGA6/NT5E/STX11/ITGB8/NRP1/CD44/AHNAK/PLAAT3/APOL3/IL2RB | 13 |
| GOBP_NEGATIVE_REGULATION_OF_PROTEIN_BINDING | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_BINDING | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_BINDING | 13/1438 | 97/23056 | 0.1340206 | 2.148804 | 2.924215 | 0.0071706 | 0.0278388 | 0.0178966 | ITGA4/XIRP1/DAB2/ADRB2/HFE/CAV1/DKK1/CARD16/NFATC4/DACT1/NOG/TMC8/PDGFB | 13 |
| HP_CYANOSIS | HP_CYANOSIS | HP_CYANOSIS | 13/1438 | 97/23056 | 0.1340206 | 2.148804 | 2.924215 | 0.0071706 | 0.0278388 | 0.0178966 | AGRN/FUCA1/COL5A2/DOK7/SLC34A2/GJA1/CITED2/COL5A1/COL13A1/ACTC1/COL1A1/GATA6/SCN1B | 13 |
| ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN | ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN | ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN | 15/1438 | 119/23056 | 0.1260504 | 2.021014 | 2.879992 | 0.0071796 | 0.0278660 | 0.0179141 | PTPN22/CFH/LCT/SLC12A8/ENAM/HOXA1/HOXA7/C7orf33/MYBL1/DRAM1/ZIC2/TPM1/CLUL1/MID1/ZNF185 | 15 |
| GOBP_ACTIN_CYTOSKELETON_REORGANIZATION | GOBP_ACTIN_CYTOSKELETON_REORGANIZATION | GOBP_ACTIN_CYTOSKELETON_REORGANIZATION | 14/1438 | 108/23056 | 0.1296296 | 2.078401 | 2.897170 | 0.0072285 | 0.0280400 | 0.0180259 | S1PR1/HMCN1/IQGAP2/MICALL2/TEK/ANXA1/GSN/NRP1/ARHGDIB/EPS8/PLEK2/CSF3/GMFG/MYH9 | 14 |
| GOBP_REGULATION_OF_EXTENT_OF_CELL_GROWTH | GOBP_REGULATION_OF_EXTENT_OF_CELL_GROWTH | GOBP_REGULATION_OF_EXTENT_OF_CELL_GROWTH | 14/1438 | 108/23056 | 0.1296296 | 2.078401 | 2.897170 | 0.0072285 | 0.0280400 | 0.0180259 | CRABP2/FN1/SEMA3B/WNT5A/SPP1/SEMA5A/SEMA3C/SEMA3A/SEMA3D/NRP1/TRPV2/SEMA6B/MAG/APOE | 14 |
| GOBP_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | GOBP_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | GOBP_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | 19/1438 | 165/23056 | 0.1151515 | 1.846268 | 2.813661 | 0.0072497 | 0.0281061 | 0.0180685 | MCOLN2/CASQ1/PTPRC/ATP2B4/TRPC3/ITPR3/TRDN/CAV1/TRPA1/UBASH3B/TPCN1/PRKD1/SLC24A4/BDKRB1/TRPV2/CCR7/HAP1/PRNP/JPH2 | 19 |
| GOBP_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | GOBP_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | GOBP_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS | 19/1438 | 165/23056 | 0.1151515 | 1.846268 | 2.813661 | 0.0072497 | 0.0281061 | 0.0180685 | PTGS2/CD34/EPHA4/PPARG/EDN1/CITED2/AQP1/CAV1/STC1/AQP3/NOTCH1/FAS/CARD16/FOXO1/AJUBA/ZFP36L1/GATA6/PTGIS/HMOX1 | 19 |
| GOBP_STEM_CELL_PROLIFERATION | GOBP_STEM_CELL_PROLIFERATION | GOBP_STEM_CELL_PROLIFERATION | 11/1438 | 76/23056 | 0.1447368 | 2.320621 | 2.974159 | 0.0072879 | 0.0282383 | 0.0181535 | PTPRC/CD34/WNT5A/VEGFC/GJA1/YAP1/WNT10B/HMGA2/ZFP36L1/RUNX1/WNT7B | 11 |
| GOBP_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE | 11/1438 | 76/23056 | 0.1447368 | 2.320621 | 2.974159 | 0.0072879 | 0.0282383 | 0.0181535 | ZC3H12A/NLRP3/BCL6/LEF1/IL6/ANXA1/STAT6/IL4R/IL12RB1/BCL3/RELB | 11 |
| HP_TOOTH_MALPOSITION | HP_TOOTH_MALPOSITION | HP_TOOTH_MALPOSITION | 33/1438 | 338/23056 | 0.0976331 | 1.565389 | 2.700692 | 0.0073343 | 0.0284100 | 0.0182638 | HSPG2/KCNN3/TGFA/ITGB6/COL3A1/WNT5A/FGFR3/ENAM/FAT4/ADAMTS2/EDN1/RUNX2/TENT5A/GJA1/TMEM270/ASPH/TRPS1/TPM2/COL5A1/FGFR2/WNT10B/ITGA7/GRIP1/FREM2/PRKD1/BMP4/SIX1/FBN1/DLX4/DLX3/KCNJ2/BMP2/GPC4 | 33 |
| DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | 30/1438 | 300/23056 | 0.1000000 | 1.603338 | 2.712861 | 0.0073955 | 0.0286391 | 0.0184111 | IFI44L/CCN1/GBP1/IFI16/NMI/SP100/BHLHE40/BCL6/CXCL8/CXCL1/CXCL2/CAP2/ID4/PSMB9/CCN2/TNFAIP3/ANXA1/IFITM3/ADM/YAP1/OASL/IRF9/NFKBIA/ACSM3/CCL5/IFI35/ZFP36/CEBPB/MX2/MID1 | 30 |
| BIOCARTA_HIVNEF_PATHWAY | BIOCARTA_HIVNEF_PATHWAY | BIOCARTA_HIVNEF_PATHWAY | 9/1438 | 56/23056 | 0.1607143 | 2.576793 | 3.046906 | 0.0074110 | 0.0286748 | 0.0184340 | TNFRSF1B/CASP8/TRAF1/GSN/FAS/BIRC3/TNFRSF1A/ARHGDIB/NFKBIA | 9 |
| DIRMEIER_LMP1_RESPONSE_LATE_UP | DIRMEIER_LMP1_RESPONSE_LATE_UP | DIRMEIER_LMP1_RESPONSE_LATE_UP | 9/1438 | 56/23056 | 0.1607143 | 2.576793 | 3.046906 | 0.0074110 | 0.0286748 | 0.0184340 | TNFRSF1B/RUNX3/MDFIC/TRAF1/NFKB2/CRIP1/IL4R/PIEZO1/HMOX1 | 9 |
| REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | 9/1438 | 56/23056 | 0.1607143 | 2.576793 | 3.046906 | 0.0074110 | 0.0286748 | 0.0184340 | NLRP3/CASP8/IRAK2/TNFAIP3/NFKB2/BIRC3/CASP4/CASP1/HMOX1 | 9 |
| BRUNO_HEMATOPOIESIS | BRUNO_HEMATOPOIESIS | BRUNO_HEMATOPOIESIS | 10/1438 | 66/23056 | 0.1515152 | 2.429300 | 2.999025 | 0.0074621 | 0.0288157 | 0.0185246 | TIE1/CD53/PTGS2/VAMP5/BHLHE40/TEC/SPARC/TSPAN32/ANXA2/ADGRE1 | 10 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | GOBP_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | GOBP_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION | 10/1438 | 66/23056 | 0.1515152 | 2.429300 | 2.999025 | 0.0074621 | 0.0288157 | 0.0185246 | GBP1/PHLDB2/BCL6/HOXA7/SERPINE1/NOTCH1/FZD4/MMP14/THBS1/COL1A1 | 10 |
| GOBP_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | GOBP_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | GOBP_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 10/1438 | 66/23056 | 0.1515152 | 2.429300 | 2.999025 | 0.0074621 | 0.0288157 | 0.0185246 | GBP1/PTPN22/PTPRC/PTPRJ/TESPA1/CCR7/CD22/KCNN4/NECTIN2/PRNP | 10 |
| HP_ECTRODACTYLY | HP_ECTRODACTYLY | HP_ECTRODACTYLY | 10/1438 | 66/23056 | 0.1515152 | 2.429300 | 2.999025 | 0.0074621 | 0.0288157 | 0.0185246 | ITGB6/FGFRL1/FGFR3/GLI3/PLAG1/NOTCH1/FGFR2/WNT10B/HMGA2/MMP2 | 10 |
| HP_URETHRAL_OBSTRUCTION | HP_URETHRAL_OBSTRUCTION | HP_URETHRAL_OBSTRUCTION | 10/1438 | 66/23056 | 0.1515152 | 2.429300 | 2.999025 | 0.0074621 | 0.0288157 | 0.0185246 | LAMC2/LAMB3/ITGA6/COL7A1/TMEM270/MMP1/DACT1/SALL1/ITGB4/RIN2 | 10 |
| PID_HIF1_TFPATHWAY | PID_HIF1_TFPATHWAY | PID_HIF1_TFPATHWAY | 10/1438 | 66/23056 | 0.1515152 | 2.429300 | 2.999025 | 0.0074621 | 0.0288157 | 0.0185246 | BHLHE40/ABCG2/EDN1/NT5E/CITED2/SERPINE1/ADM/BHLHE41/FOS/HMOX1 | 10 |
| REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | 10/1438 | 66/23056 | 0.1515152 | 2.429300 | 2.999025 | 0.0074621 | 0.0288157 | 0.0185246 | CYP26B1/AHRR/CYP39A1/AHR/CYP26A1/CYP46A1/CYP19A1/CYP4F11/PTGIS/CYP24A1 | 10 |
| WP_HEPATITIS_B_INFECTION | WP_HEPATITIS_B_INFECTION | WP_HEPATITIS_B_INFECTION | 18/1438 | 154/23056 | 0.1168831 | 1.874031 | 2.806758 | 0.0075764 | 0.0292486 | 0.0188030 | HSPG2/IKBKE/TGFB2/CASP10/CASP8/TGFBR2/CXCL8/TLR3/IL6/DDX58/FAS/CREB3L1/STAT6/NFATC4/FOS/CREB3L3/TGFB1/NFATC2 | 18 |
| XU_GH1_AUTOCRINE_TARGETS_DN | XU_GH1_AUTOCRINE_TARGETS_DN | XU_GH1_AUTOCRINE_TARGETS_DN | 16/1438 | 131/23056 | 0.1221374 | 1.958275 | 2.836779 | 0.0075800 | 0.0292544 | 0.0188066 | TNFRSF4/PLK2/SLC22A23/COL12A1/PTPRK/SEMA3C/PODXL/RBPMS/SULF1/B4GALT1/PTPN3/CD44/PLAAT3/KRT80/THBS1/TPM1 | 16 |
| GOBP_POST_EMBRYONIC_DEVELOPMENT | GOBP_POST_EMBRYONIC_DEVELOPMENT | GOBP_POST_EMBRYONIC_DEVELOPMENT | 12/1438 | 87/23056 | 0.1379310 | 2.211501 | 2.919890 | 0.0076416 | 0.0294757 | 0.0189489 | EFEMP1/HEG1/KDR/SOD2/SEMA3C/KLF4/FGFR2/ALX4/BMP4/FBN1/MYO1E/LHX1 | 12 |
| KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN | 12/1438 | 87/23056 | 0.1379310 | 2.211501 | 2.919890 | 0.0076416 | 0.0294757 | 0.0189489 | EPHA2/GPR39/COL8A1/MME/IL1RAP/MAFK/SERPINE1/MSC/PITX3/APOC3/BMP4/ALPK3 | 12 |
| GOMF_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 19/1438 | 166/23056 | 0.1144578 | 1.835146 | 2.785144 | 0.0077222 | 0.0297783 | 0.0191434 | SLC1A7/ABCG2/SLC7A11/SLC6A7/CD36/SLC26A4/SLC26A7/SLC16A12/SLC5A12/SLCO2B1/SLC6A13/SLC38A4/SLC10A2/SLC7A7/SLC47A1/ABCC3/SLC16A5/SLC16A3/SLC7A10 | 19 |
| GOBP_RECEPTOR_MEDIATED_ENDOCYTOSIS | GOBP_RECEPTOR_MEDIATED_ENDOCYTOSIS | GOBP_RECEPTOR_MEDIATED_ENDOCYTOSIS | 26/1438 | 251/23056 | 0.1035857 | 1.660828 | 2.714967 | 0.0078064 | 0.0300762 | 0.0193349 | HSPG2/LDLRAP1/LRP1B/ITGA4/ACKR3/TGFBR2/STAB1/CXCL8/EGF/DAB2/ADRB2/HFE/CD36/SERPINE1/CAV2/CAV1/MSR1/CLU/ANGPT1/DKK1/SFTPD/ADM/APOC3/ANXA2/C3/APOE | 26 |
| GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT | GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT | GOBP_REGULATION_OF_CALCIUM_ION_TRANSPORT | 26/1438 | 251/23056 | 0.1035857 | 1.660828 | 2.714967 | 0.0078064 | 0.0300762 | 0.0193349 | CASQ1/PTGS2/AGT/MYLK/HES1/EGF/TRPC3/TRDN/CAV1/STC1/TMC1/PLPP4/AHNAK/UBASH3B/PRKD1/BDKRB1/GRAMD2A/RRAD/TRPV2/CCL5/HAP1/CACNG6/PRNP/REM1/JPH2/PDGFB | 26 |
| GOBP_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_LONG_TERM_SYNAPTIC_POTENTIATION | GOBP_LONG_TERM_SYNAPTIC_POTENTIATION | 13/1438 | 98/23056 | 0.1326531 | 2.126877 | 2.883213 | 0.0078082 | 0.0300762 | 0.0193349 | EPHA4/SERPINE2/MME/PLK2/ITPR3/PTN/ADCY8/SYT12/NFATC4/CYP46A1/GIP/APOE/PRNP | 13 |
| TAKAO_RESPONSE_TO_UVB_RADIATION_DN | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | 13/1438 | 98/23056 | 0.1326531 | 2.126877 | 2.883213 | 0.0078082 | 0.0300762 | 0.0193349 | S100A5/IFI16/TNFAIP3/CEBPD/NFKB2/ADM/TNFRSF1A/FOXO1/ANXA2/CES1/SERPINB8/ZFP36/CYP24A1 | 13 |
| HP_PECTUS_EXCAVATUM | HP_PECTUS_EXCAVATUM | HP_PECTUS_EXCAVATUM | 28/1438 | 276/23056 | 0.1014493 | 1.626575 | 2.700877 | 0.0078193 | 0.0301105 | 0.0193570 | HSPG2/COL3A1/TGFBR2/WNT5A/CD96/FGFR3/COL12A1/TENT5A/FAM20C/TMEM270/MET/CSGALNACT1/TPM2/COL5A1/MYPN/EFEMP2/ITGA7/LTBP2/FBLN5/FBN1/MAF/PIEZO1/NOG/PIEZO2/RRAS/BMP2/SRPX2/GPC4 | 28 |
| HP_ABNORMAL_SYNAPTIC_TRANSMISSION_AT_THE_NEUROMUSCULAR_JUNCTION | HP_ABNORMAL_SYNAPTIC_TRANSMISSION_AT_THE_NEUROMUSCULAR_JUNCTION | HP_ABNORMAL_SYNAPTIC_TRANSMISSION_AT_THE_NEUROMUSCULAR_JUNCTION | 14/1438 | 109/23056 | 0.1284404 | 2.059333 | 2.859151 | 0.0078311 | 0.0301458 | 0.0193797 | AGRN/CASQ1/DES/EPHA4/LAMB2/DOK7/SLC34A2/PON3/FLNC/TPM2/DKK1/MYPN/COL13A1/ITGA7 | 14 |
| IVANOVA_HEMATOPOIESIS_STEM_CELL | IVANOVA_HEMATOPOIESIS_STEM_CELL | IVANOVA_HEMATOPOIESIS_STEM_CELL | 21/1438 | 190/23056 | 0.1105263 | 1.772110 | 2.756229 | 0.0078329 | 0.0301458 | 0.0193797 | S100A5/LYPD1/SLIT2/MYO10/IQGAP2/PTPRK/SASH1/SEMA3D/PTGR1/PYGM/ARHGAP42/ROBO4/EMP1/NFKBIA/HOXB2/ITGA3/SLC16A5/SERPINB8/NFATC2/COL18A1/LPAR4 | 21 |
| HP_ABNORMAL_FORM_OF_THE_VERTEBRAL_BODIES | HP_ABNORMAL_FORM_OF_THE_VERTEBRAL_BODIES | HP_ABNORMAL_FORM_OF_THE_VERTEBRAL_BODIES | 32/1438 | 327/23056 | 0.0978593 | 1.569016 | 2.672774 | 0.0079246 | 0.0304902 | 0.0196011 | HSPG2/FUCA1/PTCH2/TBX15/KYNU/FN1/WNT5A/FGFRL1/FGFR3/SGMS2/SPARC/RUNX2/TENT5A/GJA1/GLI3/TMEM270/SHH/CSGALNACT1/PAPSS2/FGFR2/SERPINH1/ZIC2/MMP14/FBN1/MMP2/FOXF1/COL1A1/PIEZO2/TNFRSF11A/COL9A3/ARSL/BGN | 32 |
| HP_ABNORMALITY_OF_THE_SMALL_INTESTINE | HP_ABNORMALITY_OF_THE_SMALL_INTESTINE | HP_ABNORMALITY_OF_THE_SMALL_INTESTINE | 25/1438 | 239/23056 | 0.1046025 | 1.677132 | 2.713920 | 0.0079579 | 0.0305963 | 0.0196693 | FCGR2A/PLA2G4A/ACTG2/LCT/RARB/FGFRL1/ADAMTS3/PCSK1/TNFAIP3/SHH/GAS1/TNFSF15/EFEMP2/ZIC2/SLC10A2/SLC7A7/FBLN5/SALL1/FOXF1/PLVAP/IL12RB1/TGFB1/FRMPD4/GPC4/ARHGEF6 | 25 |
| DOANE_BREAST_CANCER_ESR1_DN | DOANE_BREAST_CANCER_ESR1_DN | DOANE_BREAST_CANCER_ESR1_DN | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | CXCL8/FOXC1/SOD2/BBOX1/CRYAB/MSLN/COL9A3/MID1 | 8 |
| GOBP_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | GOBP_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | GOBP_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | TNFRSF1B/IL1B/ADAM19/ADAM9/PTPN3/APOE/BACE2/MYH9 | 8 |
| GOBP_XENOBIOTIC_TRANSPORT | GOBP_XENOBIOTIC_TRANSPORT | GOBP_XENOBIOTIC_TRANSPORT | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | CLDN1/ABCG2/GJA1/SLC22A1/SLC22A18/SLC47A1/ABCC3/ABCA8 | 8 |
| HP_ABNORMAL_PUPILLARY_FUNCTION | HP_ABNORMAL_PUPILLARY_FUNCTION | HP_ABNORMAL_PUPILLARY_FUNCTION | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | RPE65/LAMB2/SH3TC2/DNMBP/LOXL1/CACNA1A/PRNP/MYL9 | 8 |
| HP_ECCHYMOSIS | HP_ECCHYMOSIS | HP_ECCHYMOSIS | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | COL3A1/COL5A2/NABP1/ITGA2/CD109/STX11/COL5A1/COL1A1 | 8 |
| HP_HEMORRHAGE_OF_THE_EYE | HP_HEMORRHAGE_OF_THE_EYE | HP_HEMORRHAGE_OF_THE_EYE | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | HMCN1/CFH/EFEMP1/CFI/TSPAN12/FZD4/APOE/NDP | 8 |
| HP_HIGH_MYOPIA | HP_HIGH_MYOPIA | HP_HIGH_MYOPIA | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | ADAMTSL4/P3H2/FGFR3/TGFBI/LTBP2/FBN1/RIN2/COL18A1 | 8 |
| PID_IL6_7_PATHWAY | PID_IL6_7_PATHWAY | PID_IL6_7_PATHWAY | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | MITF/IL6/CEBPD/PTPRE/FOXO1/FOS/SOCS3/CEBPB | 8 |
| REACTOME_INTERLEUKIN_12_SIGNALING | REACTOME_INTERLEUKIN_12_SIGNALING | REACTOME_INTERLEUKIN_12_SIGNALING | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | SOD2/CA1/LCP1/ANXA2/SERPINB2/CNN2/IL12RB1/MSN | 8 |
| SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_2 | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | CSF1/IL1R1/RPRM/CSF2/HOXA1/PLAT/PLEK2/LHX1 | 8 |
| ZHAN_MULTIPLE_MYELOMA_CD1_DN | ZHAN_MULTIPLE_MYELOMA_CD1_DN | ZHAN_MULTIPLE_MYELOMA_CD1_DN | 8/1438 | 47/23056 | 0.1702128 | 2.729086 | 3.060348 | 0.0080034 | 0.0305963 | 0.0196693 | LAX1/HES1/GRAMD2B/ADAM19/ITPR3/TNS3/BHLHE41/SLFN11 | 8 |
| GOBP_ANDROGEN_METABOLIC_PROCESS | GOBP_ANDROGEN_METABOLIC_PROCESS | GOBP_ANDROGEN_METABOLIC_PROCESS | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | SRD5A2/UGT2B7/SPP1/SHH/ADM/CYP19A1 | 6 |
| GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | GOBP_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | MR1/ERAP2/HFE/HLA-E/HLA-C/TAPBP | 6 |
| GOBP_STEM_CELL_DIVISION | GOBP_STEM_CELL_DIVISION | GOBP_STEM_CELL_DIVISION | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | TGFB2/LBH/WWTR1/EXT1/NOTCH1/ESRRB | 6 |
| GOCC_PODOSOME | GOCC_PODOSOME | GOCC_PODOSOME | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | VCAM1/SCIN/ARHGEF5/GSN/VCL/LCP1 | 6 |
| HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN | HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN | HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_DN | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | IER3/GPRC5A/KRT8/ANXA2/GDF15/TFAP2C | 6 |
| HP_ADIPOSE_TISSUE_LOSS | HP_ADIPOSE_TISSUE_LOSS | HP_ADIPOSE_TISSUE_LOSS | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | PPARG/PSMB8/CAV1/FOS/FBN1/CAVIN1 | 6 |
| HP_APLASIA_HYPOPLASIA_OF_THE_SCAPULAE | HP_APLASIA_HYPOPLASIA_OF_THE_SCAPULAE | HP_APLASIA_HYPOPLASIA_OF_THE_SCAPULAE | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | TBX15/FGFR3/PSMB8/RUNX2/RSPO2/SOX9 | 6 |
| HP_IRON_DEFICIENCY_ANEMIA | HP_IRON_DEFICIENCY_ANEMIA | HP_IRON_DEFICIENCY_ANEMIA | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | PLA2G4A/CASP10/FN1/COL7A1/FAS/MMP1 | 6 |
| PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6 | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | AOX1/RBM24/PDK4/AMIGO2/LOXL1/IL2RB | 6 |
| WATANABE_COLON_CANCER_MSI_VS_MSS_UP | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | PLA2G4A/TFAP2A/MYRF/ZIC2/CRIP1/SOX8 | 6 |
| WP_RAS_AND_BRADYKININ_PATHWAYS_IN_COVID19 | WP_RAS_AND_BRADYKININ_PATHWAYS_IN_COVID19 | WP_RAS_AND_BRADYKININ_PATHWAYS_IN_COVID19 | 6/1438 | 29/23056 | 0.2068966 | 3.317251 | 3.220384 | 0.0080034 | 0.0305963 | 0.0196693 | AGT/IL1A/IL1B/SERPINE1/BDKRB1/CYP24A1 | 6 |
| HP_ABNORMAL_CIRCULATING_LIPID_CONCENTRATION | HP_ABNORMAL_CIRCULATING_LIPID_CONCENTRATION | HP_ABNORMAL_CIRCULATING_LIPID_CONCENTRATION | 27/1438 | 264/23056 | 0.1022727 | 1.639778 | 2.696460 | 0.0080181 | 0.0306436 | 0.0196997 | LDLRAP1/PLA2G4A/CFH/PPARG/COL7A1/PSMB8/PSMB9/PLA2G7/STX11/TMEM270/CAV1/TNFSF15/MMP1/APOC3/APOA1/SLC7A7/PYGL/FOS/FBN1/CYP19A1/CETP/PSMB10/CAVIN1/CREB3L3/PLVAP/IL12RB1/APOE | 27 |
| GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | GOBP_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 11/1438 | 77/23056 | 0.1428571 | 2.290483 | 2.925407 | 0.0080361 | 0.0306782 | 0.0197220 | KCNE4/DSP/TBX18/GJA1/CAV1/KCNA5/HCN4/JUP/KCNJ2/DSG2/SCN1B | 11 |
| GOBP_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 11/1438 | 77/23056 | 0.1428571 | 2.290483 | 2.925407 | 0.0080361 | 0.0306782 | 0.0197220 | GFI1/PTPN22/RAB7B/TLR3/F2RL1/TNFAIP3/CD36/CAV1/NLRP6/BIRC3/IFI35 | 11 |
| HP_SKIN_TAGS | HP_SKIN_TAGS | HP_SKIN_TAGS | 11/1438 | 77/23056 | 0.1428571 | 2.290483 | 2.925407 | 0.0080361 | 0.0306782 | 0.0197220 | PTCH2/FN1/FGFRL1/SEMA5A/EDN1/FGFR2/DACT1/SIX1/SALL1/SIX5/GPC4 | 11 |
| NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | 11/1438 | 77/23056 | 0.1428571 | 2.290483 | 2.925407 | 0.0080361 | 0.0306782 | 0.0197220 | FGFR3/FGF18/CAP2/MDFI/SIM1/FGFR2/SIX1/COL9A3/COL4A5/GPC4/MAGEA9 | 11 |
| FOSTER_TOLERANT_MACROPHAGE_UP | FOSTER_TOLERANT_MACROPHAGE_UP | FOSTER_TOLERANT_MACROPHAGE_UP | 19/1438 | 167/23056 | 0.1137725 | 1.824157 | 2.756824 | 0.0082194 | 0.0312358 | 0.0200804 | TNFRSF1B/MCOLN2/GALNT15/SLC7A11/ELL2/TGFBI/HLA-E/MET/MSR1/RBPMS/MS4A4A/PPM1H/TMCC3/RAB20/THBS1/SMAD6/NUPR1/SLC16A3/FPR1 | 19 |
| CHIBA_RESPONSE_TO_TSA_DN | CHIBA_RESPONSE_TO_TSA_DN | CHIBA_RESPONSE_TO_TSA_DN | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | TGFB2/CXCL8/DSP/ADAM9/BIRC3 | 5 |
| GOBP_CARDIAC_RIGHT_VENTRICLE_MORPHOGENESIS | GOBP_CARDIAC_RIGHT_VENTRICLE_MORPHOGENESIS | GOBP_CARDIAC_RIGHT_VENTRICLE_MORPHOGENESIS | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | TGFB2/SEMA3C/ZFPM2/NOTCH1/BMP4 | 5 |
| GOBP_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS | GOBP_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS | GOBP_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | PTGS2/HAS2/KLF4/MMP2/KLF2 | 5 |
| GOBP_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION | GOBP_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION | GOBP_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | TXK/TEC/KDR/DDR1/CAV1 | 5 |
| GOBP_POSITIVE_REGULATION_OF_CARDIOCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_CARDIOCYTE_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_CARDIOCYTE_DIFFERENTIATION | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | TGFB2/BMP4/MYOCD/GATA6/TGFB1 | 5 |
| GOBP_REGULATION_OF_URINE_VOLUME | GOBP_REGULATION_OF_URINE_VOLUME | GOBP_REGULATION_OF_URINE_VOLUME | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | NPR3/EDN1/HAS2/ADM/EDNRB | 5 |
| GOBP_RESPONSE_TO_MUSCLE_ACTIVITY | GOBP_RESPONSE_TO_MUSCLE_ACTIVITY | GOBP_RESPONSE_TO_MUSCLE_ACTIVITY | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | PERM1/AGT/ITGA2/TNS2/METRNL | 5 |
| GOBP_T_HELPER_1_CELL_DIFFERENTIATION | GOBP_T_HELPER_1_CELL_DIFFERENTIATION | GOBP_T_HELPER_1_CELL_DIFFERENTIATION | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | LEF1/ANXA1/STAT6/IL4R/RELB | 5 |
| GOCC_STRIATED_MUSCLE_THIN_FILAMENT | GOCC_STRIATED_MUSCLE_THIN_FILAMENT | GOCC_STRIATED_MUSCLE_THIN_FILAMENT | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | LMOD1/TNNC1/LMOD2/TPM2/TPM1 | 5 |
| HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_UP | HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_UP | HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_UP | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | PTPN7/IL1RAP/LTK/MEOX1/RUNX1 | 5 |
| HP_BILATERAL_CLEFT_LIP | HP_BILATERAL_CLEFT_LIP | HP_BILATERAL_CLEFT_LIP | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | SHH/RSPO2/YAP1/ZIC2/DLX4 | 5 |
| HP_CALCIFICATION_OF_THE_AORTA | HP_CALCIFICATION_OF_THE_AORTA | HP_CALCIFICATION_OF_THE_AORTA | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | LDLRAP1/SLC34A2/NOTCH1/SMAD6/GATA5 | 5 |
| HP_MICRONODULAR_CIRRHOSIS | HP_MICRONODULAR_CIRRHOSIS | HP_MICRONODULAR_CIRRHOSIS | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | CASP8/MET/PDGFRL/KRT8/KRT18 | 5 |
| HP_PREMATURE_LOSS_OF_PRIMARY_TEETH | HP_PREMATURE_LOSS_OF_PRIMARY_TEETH | HP_PREMATURE_LOSS_OF_PRIMARY_TEETH | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | COL3A1/GJA1/C1S/C1R/PRKD1 | 5 |
| HP_PULMONARY_EDEMA | HP_PULMONARY_EDEMA | HP_PULMONARY_EDEMA | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | CFH/CFI/EPHB4/FLNC/MYPN | 5 |
| HP_SKIN_EROSION | HP_SKIN_EROSION | HP_SKIN_EROSION | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | LAMC2/LAMB3/COL7A1/DSP/ITGB4 | 5 |
| MALTA_CURATED_STEMNESS_MARKERS | MALTA_CURATED_STEMNESS_MARKERS | MALTA_CURATED_STEMNESS_MARKERS | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | CD34/ABCG2/KLF4/NOTCH1/CD44 | 5 |
| MURAKAMI_UV_RESPONSE_6HR_DN | MURAKAMI_UV_RESPONSE_6HR_DN | MURAKAMI_UV_RESPONSE_6HR_DN | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | EDN2/TGFB2/IL6/KRT13/TGFB1 | 5 |
| REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX | REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX | REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | PTGR1/ALOX5/ALOX5AP/CYP4F11/GGT1 | 5 |
| SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_DN | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_DN | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_2FC_DN | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | CTSS/LEF1/ADM/IGF1/IL32 | 5 |
| TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_UP | TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_UP | TUOMISTO_TUMOR_SUPPRESSION_BY_COL13A1_UP | 5/1438 | 21/23056 | 0.2380952 | 3.817471 | 3.331419 | 0.0082322 | 0.0312358 | 0.0200804 | SLC34A2/ITGA8/MS4A4A/SERPINA1/MT1X | 5 |
| REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS | REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS | REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS | 40/1438 | 432/23056 | 0.0925926 | 1.484572 | 2.622225 | 0.0082627 | 0.0313431 | 0.0201494 | TGFA/FN1/TGFBR2/HES1/FGFR3/KDR/EPGN/EREG/BTC/FGF5/EGF/HBEGF/FGF18/PSMB8/PSMB9/PDGFA/MET/SHH/FGF20/FZD6/NOTCH1/APBB1IP/FZD8/DKK1/VCL/TCF7L2/FGFR2/FZD4/MAML2/VWF/FLT3/FOXO1/BCL2A1/PSMB10/TGFB1/CEBPB/MYH9/RAC2/PDGFB/MSN | 40 |
| GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN | GOMF_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN | 20/1438 | 179/23056 | 0.1117318 | 1.791439 | 2.741566 | 0.0082867 | 0.0313607 | 0.0201608 | CYP4X1/FMO3/PTGS2/CYP26B1/P3H2/CYP39A1/MOXD1/ASPH/PTGS1/AKR1C3/CYP26A1/MICAL2/BBOX1/P4HA3/CYP46A1/CYP19A1/CYP4F11/PTGIS/CYP24A1/HMOX1 | 20 |
| GOCC_NEUROMUSCULAR_JUNCTION | GOCC_NEUROMUSCULAR_JUNCTION | GOCC_NEUROMUSCULAR_JUNCTION | 10/1438 | 67/23056 | 0.1492537 | 2.393042 | 2.945071 | 0.0082937 | 0.0313607 | 0.0201608 | SYNC/DES/EPHA4/SERPINE2/LAMB2/LAMA2/UTRN/CDH15/MYH9/COL4A5 | 10 |
| GOMF_SCAFFOLD_PROTEIN_BINDING | GOMF_SCAFFOLD_PROTEIN_BINDING | GOMF_SCAFFOLD_PROTEIN_BINDING | 10/1438 | 67/23056 | 0.1492537 | 2.393042 | 2.945071 | 0.0082937 | 0.0313607 | 0.0201608 | ATP2B4/CASP8/GRID2/DSP/GJA1/CAV2/KCNA5/KRT8/KRT18/KRT15 | 10 |
| HP_ABNORMAL_PULMONARY_VALVE_MORPHOLOGY | HP_ABNORMAL_PULMONARY_VALVE_MORPHOLOGY | HP_ABNORMAL_PULMONARY_VALVE_MORPHOLOGY | 10/1438 | 67/23056 | 0.1492537 | 2.393042 | 2.945071 | 0.0082937 | 0.0313607 | 0.0201608 | TGFBR2/RREB1/SHH/NOTCH1/ZIC2/DACT1/SALL1/FOXF1/RNF135/RRAS | 10 |
| HP_ABNORMALITY_OF_SKELETAL_MUSCLE_FIBER_SIZE | HP_ABNORMALITY_OF_SKELETAL_MUSCLE_FIBER_SIZE | HP_ABNORMALITY_OF_SKELETAL_MUSCLE_FIBER_SIZE | 10/1438 | 67/23056 | 0.1492537 | 2.393042 | 2.945071 | 0.0082937 | 0.0313607 | 0.0201608 | CASQ1/COL6A3/PPARG/COL12A1/LAMA2/TPM2/MYPN/CRYAB/ITGA7/COL6A2 | 10 |
| APPIERTO_RESPONSE_TO_FENRETINIDE_UP | APPIERTO_RESPONSE_TO_FENRETINIDE_UP | APPIERTO_RESPONSE_TO_FENRETINIDE_UP | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | CCN1/NID1/TM4SF1/MMP3/MYO1E/GDF15/SDC4 | 7 |
| GOBP_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | GOBP_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | DLX1/DLX2/BCL6/TCIM/MMP14/NFKBIA/MAGEA1 | 7 |
| GOBP_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | GOBP_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | WNT5A/RUNX2/FAM20C/SULF1/CREB3L1/THBS1/NOG | 7 |
| HP_ACUTE_KIDNEY_INJURY | HP_ACUTE_KIDNEY_INJURY | HP_ACUTE_KIDNEY_INJURY | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | CFH/CFI/SAA1/PYGM/FLT1/C3/THBD | 7 |
| HP_APHTHOUS_ULCER | HP_APHTHOUS_ULCER | HP_APHTHOUS_ULCER | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | GFI1/NLRP3/CASP10/IL17RC/IL6/FAS/ELANE | 7 |
| HP_BLADDER_DIVERTICULUM | HP_BLADDER_DIVERTICULUM | HP_BLADDER_DIVERTICULUM | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | COL3A1/COL5A2/TMEM270/COL5A1/EFEMP2/FBLN5/COL1A1 | 7 |
| REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION | REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION | REACTOME_GENE_AND_PROTEIN_EXPRESSION_BY_JAK_STAT_SIGNALING_AFTER_INTERLEUKIN_12_STIMULATION | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | SOD2/CA1/LCP1/ANXA2/SERPINB2/CNN2/MSN | 7 |
| REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | TGFA/TFAP2A/CITED2/APOE/CGB5/CGB8/TFAP2C | 7 |
| TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | TGFBR2/SERPINB1/CRYBG1/AHR/HHEX/IL4R/CD37 | 7 |
| WP_WNT_SIGNALING_IN_KIDNEY_DISEASE | WP_WNT_SIGNALING_IN_KIDNEY_DISEASE | WP_WNT_SIGNALING_IN_KIDNEY_DISEASE | 7/1438 | 38/23056 | 0.1842105 | 2.953517 | 3.108347 | 0.0083016 | 0.0313607 | 0.0201608 | WNT5A/FZD1/FZD6/FZD8/FZD4/WNT10B/WNT7B | 7 |
| GOBP_NEGATIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_NEGATIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | GOBP_NEGATIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | TGFB2/HEG1/BCL6/SLIT2/ARHGAP24/MET/ARHGAP42/CGNL1/ITGA3 | 9 |
| GOBP_OVARIAN_FOLLICLE_DEVELOPMENT | GOBP_OVARIAN_FOLLICLE_DEVELOPMENT | GOBP_OVARIAN_FOLLICLE_DEVELOPMENT | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | FOXL2/KDR/EREG/FOXC1/INHBA/DMRTA1/MMP14/MMP2/CEBPB | 9 |
| GOBP_POSITIVE_REGULATION_OF_DNA_BINDING | GOBP_POSITIVE_REGULATION_OF_DNA_BINDING | GOBP_POSITIVE_REGULATION_OF_DNA_BINDING | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | PPARG/HES1/EGF/ITGA2/FOXC1/KLF4/IGF1/MYOCD/TGFB1 | 9 |
| GOBP_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | GOBP_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | WNT5A/BCL6/IL7R/IDO1/ST3GAL1/CD274/BMP4/CCL5/BIRC7 | 9 |
| GOBP_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | GOBP_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | CASP8/F2RL1/TNFAIP3/CASP4/CASP1/CARD16/APOA1/TNFRSF1A/BIRC7 | 9 |
| GOBP_RUFFLE_ORGANIZATION | GOBP_RUFFLE_ORGANIZATION | GOBP_RUFFLE_ORGANIZATION | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | ARHGAP24/CAV1/AIF1L/EPS8L2/EPS8/TPM1/CSPG4/CCR7/ICAM1 | 9 |
| HP_ABNORMAL_MIDDLE_PHALANX_MORPHOLOGY_OF_THE_HAND | HP_ABNORMAL_MIDDLE_PHALANX_MORPHOLOGY_OF_THE_HAND | HP_ABNORMAL_MIDDLE_PHALANX_MORPHOLOGY_OF_THE_HAND | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | WNT5A/FGFR3/RUNX2/GJA1/TRPS1/FGFR2/BMP4/NOG/BMP2 | 9 |
| HP_TRANSIENT_ISCHEMIC_ATTACK | HP_TRANSIENT_ISCHEMIC_ATTACK | HP_TRANSIENT_ISCHEMIC_ATTACK | 9/1438 | 57/23056 | 0.1578947 | 2.531586 | 2.985923 | 0.0083256 | 0.0313822 | 0.0201746 | TGFB2/COL3A1/TGFBR2/MYLK/CITED2/HTRA1/ACTC1/FBN1/GATA6 | 9 |
| GOBP_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 33/1438 | 341/23056 | 0.0967742 | 1.551617 | 2.646751 | 0.0083283 | 0.0313836 | 0.0201754 | AGRN/CRABP2/AGT/ITGA6/FN1/EPHA4/WNT5A/EPHA3/SLIT2/SEMA5A/ITGA2/F2RL1/RREB1/FZD1/PTN/NRP1/EPS8L2/FZD4/EPS8/GRIP1/PRKD1/PLEK2/LTK/TRPV2/CCR7/HAP1/ITGA3/SCN1B/APOE/CDC42EP5/RAC2/CDC42EP1/TENM1 | 33 |
| HP_DERMATOLOGICAL_MANIFESTATIONS_OF_SYSTEMIC_DISORDERS | HP_DERMATOLOGICAL_MANIFESTATIONS_OF_SYSTEMIC_DISORDERS | HP_DERMATOLOGICAL_MANIFESTATIONS_OF_SYSTEMIC_DISORDERS | 29/1438 | 290/23056 | 0.1000000 | 1.603338 | 2.666678 | 0.0083458 | 0.0314354 | 0.0202088 | AGRN/FUCA1/GYPC/COL5A2/SP110/CLDN1/DOK7/SLC34A2/RHAG/GJA1/CITED2/STX11/SLC26A4/PTPN3/TNFSF15/GSN/COL5A1/COL13A1/KRT8/KRT18/SERPINA1/ACTC1/EPB42/PIEZO1/COL1A1/GATA6/IL12RB1/SCN1B/KCNN4 | 29 |
| IWANAGA_CARCINOGENESIS_BY_KRAS_DN | IWANAGA_CARCINOGENESIS_BY_KRAS_DN | IWANAGA_CARCINOGENESIS_BY_KRAS_DN | 15/1438 | 121/23056 | 0.1239669 | 1.987609 | 2.809200 | 0.0083466 | 0.0314354 | 0.0202088 | GBP2/ITGA6/TNNC1/ITGB5/COX7B2/MYOZ2/TMEM200A/SKAP2/KLF4/FIBIN/FLT1/ITPRIPL2/ABCA6/ITGB4/TBC1D8B | 15 |
| HP_BLUE_SCLERAE | HP_BLUE_SCLERAE | HP_BLUE_SCLERAE | 12/1438 | 88/23056 | 0.1363636 | 2.186370 | 2.875770 | 0.0083598 | 0.0314764 | 0.0202351 | COL3A1/TGFBR2/WNT5A/ADAMTS2/COL12A1/TENT5A/COL5A1/CREB3L1/SERPINH1/C1R/FBN1/COL1A1 | 12 |
| RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN | 27/1438 | 265/23056 | 0.1018868 | 1.633590 | 2.675491 | 0.0084137 | 0.0316707 | 0.0203600 | ERRFI1/EPHA2/FUCA1/SP110/SP100/IRAK2/PRICKLE2/GRID2/DDO/FABP4/CA3/DDX58/TRAF1/NOTCH1/PROSER2/AIFM2/BBOX1/NNMT/LTBP2/CES1/CAVIN1/MBP/PLIN4/SLC7A10/LENG9/GPC4/ARHGEF6 | 27 |
| HP_PECTUS_CARINATUM | HP_PECTUS_CARINATUM | HP_PECTUS_CARINATUM | 17/1438 | 144/23056 | 0.1180556 | 1.892829 | 2.771868 | 0.0084288 | 0.0317100 | 0.0203853 | AGRN/HSPG2/FN1/TGFBR2/WNT5A/MME/TENT5A/TRPS1/TNFRSF11B/COL13A1/FBN1/RNF135/PIEZO2/TNFRSF11A/RRAS/BMP2/BGN | 17 |
| WP_ECTODERM_DIFFERENTIATION | WP_ECTODERM_DIFFERENTIATION | WP_ECTODERM_DIFFERENTIATION | 17/1438 | 144/23056 | 0.1180556 | 1.892829 | 2.771868 | 0.0084288 | 0.0317100 | 0.0203853 | TFAP2A/CAP2/GLI3/PODXL/SHH/STC1/TNFRSF11B/FZD8/FGFR2/FZD4/BMP4/KIFC3/LHX1/JUP/GATA6/TFAP2C/GAS2L1 | 17 |
| CHENG_IMPRINTED_BY_ESTRADIOL | CHENG_IMPRINTED_BY_ESTRADIOL | CHENG_IMPRINTED_BY_ESTRADIOL | 14/1438 | 110/23056 | 0.1272727 | 2.040612 | 2.821538 | 0.0084728 | 0.0318584 | 0.0204807 | RUNX3/RPRM/IRAK2/THRB/WNT5A/FAM126A/HOXA1/FZD1/ZNF467/TOR4A/FZD8/PAPSS2/ZFP36L1/TFAP2C | 14 |
| WOOD_EBV_EBNA1_TARGETS_UP | WOOD_EBV_EBNA1_TARGETS_UP | WOOD_EBV_EBNA1_TARGETS_UP | 14/1438 | 110/23056 | 0.1272727 | 2.040612 | 2.821538 | 0.0084728 | 0.0318584 | 0.0204807 | SPON2/FGFR3/PODXL/CLU/RBPMS/AKR1C3/BAG3/CD44/SERPINH1/C1S/NQO1/C3/ICAM1/TFAP2C | 14 |
| GOBP_STEROL_HOMEOSTASIS | GOBP_STEROL_HOMEOSTASIS | GOBP_STEROL_HOMEOSTASIS | 13/1438 | 99/23056 | 0.1313131 | 2.105393 | 2.842700 | 0.0084897 | 0.0318784 | 0.0204935 | LDLRAP1/NR5A2/CYP39A1/CAV1/FABP4/APOC3/APOA1/SOAT2/ACSM3/CES1/CETP/LIPG/APOE | 13 |
| HAHTOLA_SEZARY_SYNDROM_UP | HAHTOLA_SEZARY_SYNDROM_UP | HAHTOLA_SEZARY_SYNDROM_UP | 13/1438 | 99/23056 | 0.1313131 | 2.105393 | 2.842700 | 0.0084897 | 0.0318784 | 0.0204935 | NIBAN1/CSGALNACT1/CA1/FAS/HBD/MS4A4A/C3AR1/NFE2/GLIPR1/CRIP1/CES1/MEOX1/ITM2A | 13 |
| REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | REN_ALVEOLAR_RHABDOMYOSARCOMA_UP | 13/1438 | 99/23056 | 0.1313131 | 2.105393 | 2.842700 | 0.0084897 | 0.0318784 | 0.0204935 | KCNN3/DES/TNNC1/TSPAN12/SYNPO2L/VWF/SIX1/DIO2/ALPK3/CDH15/MEOX1/SGCA/ITM2A | 13 |
| ROVERSI_GLIOMA_COPY_NUMBER_UP | ROVERSI_GLIOMA_COPY_NUMBER_UP | ROVERSI_GLIOMA_COPY_NUMBER_UP | 13/1438 | 99/23056 | 0.1313131 | 2.105393 | 2.842700 | 0.0084897 | 0.0318784 | 0.0204935 | GALNT5/SLC7A11/GALNT10/AHR/CREB3L1/PTPRJ/GALNT9/BCL3/BCAM/NECTIN2/APOE/RELB/CKM | 13 |
| SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | 13/1438 | 99/23056 | 0.1313131 | 2.105393 | 2.842700 | 0.0084897 | 0.0318784 | 0.0204935 | LRP1B/MLPH/SEMA3B/EPHA3/FGFR3/INPP4B/CCNO/PLK2/PGGHG/RND1/CRIP1/CA12/CELSR1 | 13 |
| GOBP_PLASMA_MEMBRANE_ORGANIZATION | GOBP_PLASMA_MEMBRANE_ORGANIZATION | GOBP_PLASMA_MEMBRANE_ORGANIZATION | 18/1438 | 156/23056 | 0.1153846 | 1.850005 | 2.747391 | 0.0086247 | 0.0323763 | 0.0208136 | TIE1/SYPL2/PTPRC/TGFB2/CAVIN2/PLSCR4/PLSCR2/SH3TC2/CAV2/CAV1/CLU/GSN/COL5A1/MYOF/MYRF/EHD2/MYH9/A4GALT | 18 |
| FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 32/1438 | 329/23056 | 0.0972644 | 1.559478 | 2.636112 | 0.0086334 | 0.0323999 | 0.0208288 | S100A2/S100A13/BRINP3/KYNU/MLPH/TMEM158/SEL1L3/RBM47/EGF/INPP4B/PPIC/FOXC1/TNFRSF21/CADPS2/CLU/PAPSS2/TCF7L2/SLC22A18/P2RY2/VWA5A/SCNN1A/RND1/KRT7/KRT18/ACSS3/CES1/HOXB2/SIGLEC15/BLVRB/GGT1/APOBEC3A/MID1 | 32 |
| REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | 23/1438 | 216/23056 | 0.1064815 | 1.707258 | 2.693463 | 0.0086445 | 0.0324329 | 0.0208500 | EDN2/AGT/GPR39/HRH1/MGLL/TRPC3/F2RL1/HBEGF/EDN1/ITPR3/HCRTR2/ANXA1/CCKBR/SAA1/P2RY2/MMP3/EDNRB/BDKRB1/GPR132/GNGT2/ADRA1D/CYSLTR1/LPAR4 | 23 |
| GOMF_GATED_CHANNEL_ACTIVITY | GOMF_GATED_CHANNEL_ACTIVITY | GOMF_GATED_CHANNEL_ACTIVITY | 33/1438 | 342/23056 | 0.0964912 | 1.547081 | 2.628886 | 0.0086834 | 0.0325699 | 0.0209380 | MCOLN2/KCNN3/TMEM63A/TMEM37/KCNE4/TRPM8/GRID2/ITPR3/CLIC5/AQP1/TRPA1/TMC1/CLIC3/LRRC55/CATSPER1/CACNA2D4/KCNA5/SCNN1A/KCNH3/TPCN1/HCN4/PIEZO1/KCNJ2/TMC8/PIEZO2/CACNA1A/SCN1B/KCNK6/KCNN4/KCNA7/CACNG6/CLIC6/GABRE | 33 |
| HP_ELEVATED_PULMONARY_ARTERY_PRESSURE | HP_ELEVATED_PULMONARY_ARTERY_PRESSURE | HP_ELEVATED_PULMONARY_ARTERY_PRESSURE | 16/1438 | 133/23056 | 0.1203008 | 1.928828 | 2.770636 | 0.0087339 | 0.0327503 | 0.0210541 | HSPG2/LAMB2/FGFR3/GJA1/LAMA2/CCN2/CITED2/CAV1/NOTCH1/KRT8/KRT18/ACTC1/FBN1/FOXF1/COL1A1/GATA6 | 16 |
| GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 25/1438 | 241/23056 | 0.1037344 | 1.663214 | 2.669353 | 0.0088063 | 0.0330129 | 0.0212228 | SLC1A7/SLC12A8/SLCO2A1/SLC34A2/SLC4A4/SLC7A11/SLC12A7/SLC6A7/SLC22A1/SLC26A4/SLC26A7/SLC16A12/SLC22A18/SLC5A12/SLC15A3/SLCO2B1/SLC6A13/SLC38A4/SLC10A2/SLC24A4/SLC28A1/SLC47A1/SLC16A5/SLC16A3/SLC6A16 | 25 |
| GOBP_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT | GOBP_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT | 11/1438 | 78/23056 | 0.1410256 | 2.261118 | 2.877405 | 0.0088425 | 0.0331393 | 0.0213041 | RUNX3/LAMB2/CLDN1/GDNF/SH3TC2/CITED2/ADGRG6/EDNRB/SOX8/ITGB4/RUNX1 | 11 |
| GOBP_MEMORY | GOBP_MEMORY | GOBP_MEMORY | 15/1438 | 122/23056 | 0.1229508 | 1.971317 | 2.774312 | 0.0089840 | 0.0336423 | 0.0216275 | PTGS2/HRH1/PLK2/ITPR3/PTN/ADCY8/ITGA8/ITGA5/NFATC4/GIP/ITGA3/APOE/PRNP/LRRN4/CEBPB | 15 |
| GOBP_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 15/1438 | 122/23056 | 0.1229508 | 1.971317 | 2.774312 | 0.0089840 | 0.0336423 | 0.0216275 | PTPN22/LAX1/AGT/IL1B/PPARG/HEG1/TNFAIP3/CAV1/HHEX/PTPRJ/LATS2/BMP4/MYOCD/APOE/BMP2 | 15 |
| HP_PRURITUS | HP_PRURITUS | HP_PRURITUS | 15/1438 | 122/23056 | 0.1229508 | 1.971317 | 2.774312 | 0.0089840 | 0.0336423 | 0.0216275 | TNFRSF1B/NLRP3/IL17RC/COL7A1/IL7R/OSMR/IL31RA/DSP/PERP/GPNMB/PTPN3/TNFSF15/GSN/IL12RB1/RUNX1 | 15 |
| GOBP_ESTABLISHMENT_OF_CELL_POLARITY | GOBP_ESTABLISHMENT_OF_CELL_POLARITY | GOBP_ESTABLISHMENT_OF_CELL_POLARITY | 17/1438 | 145/23056 | 0.1172414 | 1.879776 | 2.740868 | 0.0090100 | 0.0336669 | 0.0216433 | CYP26B1/WNT5A/AMOTL2/HES1/DOCK2/GJA1/UST/SHH/GSN/CRB2/FOXF1/CCR7/ANKFN1/LLGL2/ALPK2/MYH9/MSN | 17 |
| GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS | 17/1438 | 145/23056 | 0.1172414 | 1.879776 | 2.740868 | 0.0090100 | 0.0336669 | 0.0216433 | DLX1/GDNF/SOD2/PTPRZ1/FGF20/ANGPT1/NRP1/NFATC4/SIX1/SIX4/FOXB1/IL27RA/MAG/AXL/APOE/CEBPB/HMOX1 | 17 |
| HP_VASCULAR_NEOPLASM | HP_VASCULAR_NEOPLASM | HP_VASCULAR_NEOPLASM | 17/1438 | 145/23056 | 0.1172414 | 1.879776 | 2.740868 | 0.0090100 | 0.0336669 | 0.0216433 | GFI1/WNT5A/CD96/FGFRL1/KDR/TFAP2A/TENT5A/GLI3/EPHB4/SHH/TEK/GAS1/NOTCH1/FGFR2/ZIC2/ELANE/NDP | 17 |
| GOBP_FATTY_ACID_METABOLIC_PROCESS | GOBP_FATTY_ACID_METABOLIC_PROCESS | GOBP_FATTY_ACID_METABOLIC_PROCESS | 37/1438 | 395/23056 | 0.0936709 | 1.501861 | 2.594756 | 0.0090448 | 0.0336669 | 0.0216433 | EDN2/PTGS2/PLA2G4A/IL1B/PPARG/MGLL/TECRL/ACOT12/ADTRP/EDN1/CD36/PDK4/CAV1/ANXA1/PTGR1/PTGS1/AKR1C3/ALOX5/ACSL5/APOC3/APOA1/TNFRSF1A/ALOX5AP/PLA2G4D/ACSM3/CES1/GIP/ACSF2/SOX9/LIPG/C3/CYP4F11/PLA2G4C/PTGIS/CYP24A1/GGT1/PNPLA3 | 37 |
| BROWNE_HCMV_INFECTION_8HR_DN | BROWNE_HCMV_INFECTION_8HR_DN | BROWNE_HCMV_INFECTION_8HR_DN | 8/1438 | 48/23056 | 0.1666667 | 2.672230 | 2.991103 | 0.0090917 | 0.0336669 | 0.0216433 | CEBPD/MSC/PLAU/VWA5A/NAV3/BMP4/ITGA3/MAGEA10 | 8 |
| GERHOLD_ADIPOGENESIS_UP | GERHOLD_ADIPOGENESIS_UP | GERHOLD_ADIPOGENESIS_UP | 8/1438 | 48/23056 | 0.1666667 | 2.672230 | 2.991103 | 0.0090917 | 0.0336669 | 0.0216433 | AGT/PPARG/CD36/FABP4/ITGA7/IGF1/APOE/CEBPB | 8 |
| GOBP_CALCINEURIN_MEDIATED_SIGNALING | GOBP_CALCINEURIN_MEDIATED_SIGNALING | GOBP_CALCINEURIN_MEDIATED_SIGNALING | 8/1438 | 48/23056 | 0.1666667 | 2.672230 | 2.991103 | 0.0090917 | 0.0336669 | 0.0216433 | NR5A2/ATP2B4/MYOZ2/MYOZ1/IGF1/NFATC4/PRNP/NFATC2 | 8 |
| GOBP_REGULATION_OF_P38MAPK_CASCADE | GOBP_REGULATION_OF_P38MAPK_CASCADE | GOBP_REGULATION_OF_P38MAPK_CASCADE | 8/1438 | 48/23056 | 0.1666667 | 2.672230 | 2.991103 | 0.0090917 | 0.0336669 | 0.0216433 | ZC3H12A/PTPN22/IL1B/SASH1/GDF6/BMP4/GADD45B/BMP2 | 8 |
| GOMF_CHEMOKINE_ACTIVITY | GOMF_CHEMOKINE_ACTIVITY | GOMF_CHEMOKINE_ACTIVITY | 8/1438 | 48/23056 | 0.1666667 | 2.672230 | 2.991103 | 0.0090917 | 0.0336669 | 0.0216433 | CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/CCL26/CCL5 | 8 |
| HP_ABNORMALITY_OF_THE_PUBIC_HAIR | HP_ABNORMALITY_OF_THE_PUBIC_HAIR | HP_ABNORMALITY_OF_THE_PUBIC_HAIR | 8/1438 | 48/23056 | 0.1666667 | 2.672230 | 2.991103 | 0.0090917 | 0.0336669 | 0.0216433 | CCDC141/FOXL2/ZFPM2/WT1/BNC1/SOX9/ITGB4/AXL | 8 |
| BIOCARTA_RANKL_PATHWAY | BIOCARTA_RANKL_PATHWAY | BIOCARTA_RANKL_PATHWAY | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | FOSL1/IRF9/FOS/TNFRSF11A | 4 |
| DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | OLFML3/ATP2B4/PLK2/MOXD1 | 4 |
| DORN_ADENOVIRUS_INFECTION_48HR_UP | DORN_ADENOVIRUS_INFECTION_48HR_UP | DORN_ADENOVIRUS_INFECTION_48HR_UP | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | ELF3/NFKB2/ANPEP/BACE2 | 4 |
| GOBP_ACTIVATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_ACTIVATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | GOBP_ACTIVATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | EGF/PDGFC/ADRB2/ANGPT1 | 4 |
| GOBP_COMPLEMENT_DEPENDENT_CYTOTOXICITY | GOBP_COMPLEMENT_DEPENDENT_CYTOTOXICITY | GOBP_COMPLEMENT_DEPENDENT_CYTOTOXICITY | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | CFH/TGFB2/C3/IL11 | 4 |
| GOBP_INDOLALKYLAMINE_METABOLIC_PROCESS | GOBP_INDOLALKYLAMINE_METABOLIC_PROCESS | GOBP_INDOLALKYLAMINE_METABOLIC_PROCESS | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | KYNU/TDO2/IDO1/IL4I1 | 4 |
| GOBP_LATERAL_MESODERM_DEVELOPMENT | GOBP_LATERAL_MESODERM_DEVELOPMENT | GOBP_LATERAL_MESODERM_DEVELOPMENT | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | CITED2/SHH/YAP1/FOXF1 | 4 |
| GOBP_MINERALOCORTICOID_METABOLIC_PROCESS | GOBP_MINERALOCORTICOID_METABOLIC_PROCESS | GOBP_MINERALOCORTICOID_METABOLIC_PROCESS | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | DAB2/BMP6/EDNRB/BMP2 | 4 |
| GOBP_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | GOBP_NEGATIVE_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | BCL6/ANXA1/STAT6/IL27RA | 4 |
| GOBP_NEUTROPHIL_MEDIATED_CYTOTOXICITY | GOBP_NEUTROPHIL_MEDIATED_CYTOTOXICITY | GOBP_NEUTROPHIL_MEDIATED_CYTOTOXICITY | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | CXCL6/F2RL1/NLRP6/ELANE | 4 |
| GOBP_NOSE_DEVELOPMENT | GOBP_NOSE_DEVELOPMENT | GOBP_NOSE_DEVELOPMENT | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | GLI3/SIX1/SIX4/ALDH1A3 | 4 |
| GOBP_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BETA_SIGNALING_PATHWAY | GOBP_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BETA_SIGNALING_PATHWAY | GOBP_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BETA_SIGNALING_PATHWAY | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | PDGFA/PDGFRL/MYOCD/PDGFB | 4 |
| GOBP_POSITIVE_THYMIC_T_CELL_SELECTION | GOBP_POSITIVE_THYMIC_T_CELL_SELECTION | GOBP_POSITIVE_THYMIC_T_CELL_SELECTION | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | PTPRC/ITPKB/DOCK2/SHH | 4 |
| GOBP_REGULATION_OF_FIBRINOLYSIS | GOBP_REGULATION_OF_FIBRINOLYSIS | GOBP_REGULATION_OF_FIBRINOLYSIS | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | FAP/SERPINE1/THBS1/THBD | 4 |
| GOBP_REGULATION_OF_KERATINOCYTE_MIGRATION | GOBP_REGULATION_OF_KERATINOCYTE_MIGRATION | GOBP_REGULATION_OF_KERATINOCYTE_MIGRATION | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | HBEGF/ADAM9/HAS2/EPPK1 | 4 |
| GOBP_RESPONSE_TO_UV_A | GOBP_RESPONSE_TO_UV_A | GOBP_RESPONSE_TO_UV_A | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | MME/MMP1/MMP3/MMP2 | 4 |
| GOMF_ARYLSULFATASE_ACTIVITY | GOMF_ARYLSULFATASE_ACTIVITY | GOMF_ARYLSULFATASE_ACTIVITY | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | ARSJ/ARSI/SULF1/ARSL | 4 |
| GOMF_HMG_BOX_DOMAIN_BINDING | GOMF_HMG_BOX_DOMAIN_BINDING | GOMF_HMG_BOX_DOMAIN_BINDING | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | PRRX1/HOXA3/ALX4/MEOX1 | 4 |
| GOMF_NADP_RETINOL_DEHYDROGENASE_ACTIVITY | GOMF_NADP_RETINOL_DEHYDROGENASE_ACTIVITY | GOMF_NADP_RETINOL_DEHYDROGENASE_ACTIVITY | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | DHRS3/AKR1B10/AKR1B15/AKR1C3 | 4 |
| HOEGERKORP_CD44_TARGETS_DIRECT_DN | HOEGERKORP_CD44_TARGETS_DIRECT_DN | HOEGERKORP_CD44_TARGETS_DIRECT_DN | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | SERPINA1/SLC14A1/BCAM/GUCY2F | 4 |
| HP_ANTERIOR_OPEN_BITE_MALOCCLUSION | HP_ANTERIOR_OPEN_BITE_MALOCCLUSION | HP_ANTERIOR_OPEN_BITE_MALOCCLUSION | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | KCNN3/ITGB6/ENAM/BMP2 | 4 |
| HP_APLASIA_HYPOPLASIA_OF_THE_DISTAL_PHALANGES_OF_THE_TOES | HP_APLASIA_HYPOPLASIA_OF_THE_DISTAL_PHALANGES_OF_THE_TOES | HP_APLASIA_HYPOPLASIA_OF_THE_DISTAL_PHALANGES_OF_THE_TOES | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | KCNN3/NOG/ARSL/GPC4 | 4 |
| HP_COR_PULMONALE | HP_COR_PULMONALE | HP_COR_PULMONALE | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | FCGR2A/TPM2/ITGA7/TGFB1 | 4 |
| HP_FATIGUABLE_WEAKNESS_OF_PROXIMAL_LIMB_MUSCLES | HP_FATIGUABLE_WEAKNESS_OF_PROXIMAL_LIMB_MUSCLES | HP_FATIGUABLE_WEAKNESS_OF_PROXIMAL_LIMB_MUSCLES | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | CASQ1/FLNC/TPM2/MYPN | 4 |
| HP_ILEUS | HP_ILEUS | HP_ILEUS | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | FCGR2A/WT1/CAVIN1/TGFB1 | 4 |
| HP_INCREASED_LEVEL_OF_L_FUCOSE_IN_URINE | HP_INCREASED_LEVEL_OF_L_FUCOSE_IN_URINE | HP_INCREASED_LEVEL_OF_L_FUCOSE_IN_URINE | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | CASP10/FGFR2/KRT8/KRT18 | 4 |
| HP_LARYNGEAL_STENOSIS | HP_LARYNGEAL_STENOSIS | HP_LARYNGEAL_STENOSIS | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | LAMC2/LAMB3/GRIP1/FREM2 | 4 |
| HP_SCARRING_ALOPECIA_OF_SCALP | HP_SCARRING_ALOPECIA_OF_SCALP | HP_SCARRING_ALOPECIA_OF_SCALP | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | LAMC2/LAMB3/CLDN1/ITGB4 | 4 |
| HP_SHALLOW_ANTERIOR_CHAMBER | HP_SHALLOW_ANTERIOR_CHAMBER | HP_SHALLOW_ANTERIOR_CHAMBER | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | TSPAN12/LTBP2/FBN1/NDP | 4 |
| MATZUK_POSTIMPLANTATION_AND_POSTPARTUM | MATZUK_POSTIMPLANTATION_AND_POSTPARTUM | MATZUK_POSTIMPLANTATION_AND_POSTPARTUM | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | CSF1/B4GALT1/FZD4/FOXB1 | 4 |
| PARK_APL_PATHOGENESIS_UP | PARK_APL_PATHOGENESIS_UP | PARK_APL_PATHOGENESIS_UP | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | PSMB9/AHR/ANXA1/SELPLG | 4 |
| REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | PCSK1/INHBA/CGB5/CGB8 | 4 |
| REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING | REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING | REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | RUNX3/HES1/NOTCH1/MAML2 | 4 |
| REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | SEMA3A/NRP1/RND1/RRAS | 4 |
| REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | CYP39A1/AKR1C3/CYP46A1/PTGIS | 4 |
| VICENT_METASTASIS_UP | VICENT_METASTASIS_UP | VICENT_METASTASIS_UP | 4/1438 | 14/23056 | 0.2857143 | 4.580966 | 3.456673 | 0.0091034 | 0.0336669 | 0.0216433 | SUSD5/ABCG2/CRYBG1/MICAL2 | 4 |
| GOBP_DORSAL_VENTRAL_PATTERN_FORMATION | GOBP_DORSAL_VENTRAL_PATTERN_FORMATION | GOBP_DORSAL_VENTRAL_PATTERN_FORMATION | 12/1438 | 89/23056 | 0.1348315 | 2.161804 | 2.832240 | 0.0091296 | 0.0337183 | 0.0216764 | RNF220/EDN1/MDFI/HOXA2/GLI3/SHH/GLI1/BMP4/SMAD6/LHX1/HOXB2/NOG | 12 |
| GOBP_REGULATION_OF_ANION_TRANSPORT | GOBP_REGULATION_OF_ANION_TRANSPORT | GOBP_REGULATION_OF_ANION_TRANSPORT | 12/1438 | 89/23056 | 0.1348315 | 2.161804 | 2.832240 | 0.0091296 | 0.0337183 | 0.0216764 | PLA2G4A/AGT/IL1A/IL1B/EDN1/TCAF2/STC1/CES1/TNFRSF11A/PRNP/CEBPB/GABRE | 12 |
| GOMF_ALCOHOL_BINDING | GOMF_ALCOHOL_BINDING | GOMF_ALCOHOL_BINDING | 12/1438 | 89/23056 | 0.1348315 | 2.161804 | 2.832240 | 0.0091296 | 0.0337183 | 0.0216764 | CRABP2/OSBPL10/TRPC3/ITPR3/CAV1/TPK1/APOC3/APOA1/SOAT2/TRPC4/CETP/ADAP2 | 12 |
| HP_ARNOLD_CHIARI_MALFORMATION | HP_ARNOLD_CHIARI_MALFORMATION | HP_ARNOLD_CHIARI_MALFORMATION | 12/1438 | 89/23056 | 0.1348315 | 2.161804 | 2.832240 | 0.0091296 | 0.0337183 | 0.0216764 | TGFBR2/FGFR3/TMEM270/DKK1/NFKB2/FGFR2/HMGA2/DACT1/FBN1/SALL1/MAF/FOXF1 | 12 |
| HP_OVARIAN_CYST | HP_OVARIAN_CYST | HP_OVARIAN_CYST | 12/1438 | 89/23056 | 0.1348315 | 2.161804 | 2.832240 | 0.0091296 | 0.0337183 | 0.0216764 | PPARG/FOXL2/TMEM270/CAV1/WT1/FLT1/MMP14/FOS/CYP19A1/MMP2/CAVIN1/SOX9 | 12 |
| GOCC_COATED_VESICLE | GOCC_COATED_VESICLE | GOCC_COATED_VESICLE | 29/1438 | 292/23056 | 0.0993151 | 1.592356 | 2.627268 | 0.0091382 | 0.0337411 | 0.0216910 | ECE1/LDLRAP1/CNIH3/TGFA/COL7A1/WNT5A/EPGN/EREG/BTC/EGF/IL7R/DAB2/HBEGF/ADRB2/EDN1/HLA-E/HLA-C/ADCY8/SFTPD/FZD4/VWF/SERPINA1/MYO1E/PITPNM3/COPZ2/WIPI1/APOE/KDELR3/MLC1 | 29 |
| GOCC_CLATHRIN_COATED_VESICLE_MEMBRANE | GOCC_CLATHRIN_COATED_VESICLE_MEMBRANE | GOCC_CLATHRIN_COATED_VESICLE_MEMBRANE | 14/1438 | 111/23056 | 0.1261261 | 2.022228 | 2.784322 | 0.0091554 | 0.0337954 | 0.0217259 | LDLRAP1/TGFA/WNT5A/EPGN/EREG/BTC/EGF/IL7R/DAB2/HBEGF/ADRB2/ADCY8/FZD4/APOE | 14 |
| NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON | NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON | NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON | 18/1438 | 157/23056 | 0.1146497 | 1.838222 | 2.718034 | 0.0091909 | 0.0339175 | 0.0218044 | TRPS1/EXT1/TNFRSF11B/COLEC10/COL14A1/HAS2/FBXO32/KLHL38/ANXA13/LRATD2/TMEM71/CCN4/ST3GAL1/GPR20/LY6K/GSDMD/EPPK1/PARP10 | 18 |
| KEGG_P53_SIGNALING_PATHWAY | KEGG_P53_SIGNALING_PATHWAY | KEGG_P53_SIGNALING_PATHWAY | 10/1438 | 68/23056 | 0.1470588 | 2.357850 | 2.892077 | 0.0091946 | 0.0339218 | 0.0218072 | RPRM/CASP8/SHISA5/PERP/SERPINE1/FAS/CD82/IGF1/THBS1/GADD45B | 10 |
| GOBP_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | GOBP_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION | 13/1438 | 100/23056 | 0.1300000 | 2.084339 | 2.802666 | 0.0092171 | 0.0339594 | 0.0218313 | CSF1/RAB7B/CASP8/LEF1/SCIN/INHBA/NCKAP1L/ZFP36L1/FOS/CSF3/TGFB1/RUNX1/LIF | 13 |
| GOCC_LIPID_DROPLET | GOCC_LIPID_DROPLET | GOCC_LIPID_DROPLET | 13/1438 | 100/23056 | 0.1300000 | 2.084339 | 2.802666 | 0.0092171 | 0.0339594 | 0.0218313 | DHRS3/CAV1/GIMAP2/FABP4/AQP7/AIFM2/METTL7B/ANXA2/LPCAT2/CES1/PLIN4/PLA2G4C/PNPLA3 | 13 |
| HP_BILIARY_TRACT_ABNORMALITY | HP_BILIARY_TRACT_ABNORMALITY | HP_BILIARY_TRACT_ABNORMALITY | 13/1438 | 100/23056 | 0.1300000 | 2.084339 | 2.802666 | 0.0092171 | 0.0339594 | 0.0218313 | FCGR2A/CLDN1/FGFRL1/HFE/PTPN3/TNFSF15/SERPINA1/IL21R/GATA6/IL12RB1/TGFB1/KCNN4/HMOX1 | 13 |
| MENSE_HYPOXIA_UP | MENSE_HYPOXIA_UP | MENSE_HYPOXIA_UP | 13/1438 | 100/23056 | 0.1300000 | 2.084339 | 2.802666 | 0.0092171 | 0.0339594 | 0.0218313 | BHLHE40/OSMR/FOXD1/ELL2/TSLP/SOD2/CEBPD/ASPH/KLF4/PPP1R3C/ADM/BHLHE41/CEBPB | 13 |
| REACTOME_VISUAL_PHOTOTRANSDUCTION | REACTOME_VISUAL_PHOTOTRANSDUCTION | REACTOME_VISUAL_PHOTOTRANSDUCTION | 13/1438 | 100/23056 | 0.1300000 | 2.084339 | 2.802666 | 0.0092171 | 0.0339594 | 0.0218313 | AGRN/DHRS3/HSPG2/RPE65/AKR1B10/AKR1C3/APOC3/APOA1/LRP10/APOE/SDC4/GUCY2F/GPC4 | 13 |
| GOBP_ARACHIDONIC_ACID_METABOLIC_PROCESS | GOBP_ARACHIDONIC_ACID_METABOLIC_PROCESS | GOBP_ARACHIDONIC_ACID_METABOLIC_PROCESS | 9/1438 | 58/23056 | 0.1551724 | 2.487938 | 2.926228 | 0.0093235 | 0.0343235 | 0.0220654 | PTGS2/PLA2G4A/MGLL/PTGS1/AKR1C3/ALOX5/CYP4F11/PLA2G4C/PTGIS | 9 |
| GOBP_MEMBRANE_PROTEIN_PROTEOLYSIS | GOBP_MEMBRANE_PROTEIN_PROTEOLYSIS | GOBP_MEMBRANE_PROTEIN_PROTEOLYSIS | 9/1438 | 58/23056 | 0.1551724 | 2.487938 | 2.926228 | 0.0093235 | 0.0343235 | 0.0220654 | TNFRSF1B/IL1B/ADAM19/ADAM9/PTPN3/TGFB1/APOE/BACE2/MYH9 | 9 |
| HP_RECURRENT_SINUSITIS | HP_RECURRENT_SINUSITIS | HP_RECURRENT_SINUSITIS | 9/1438 | 58/23056 | 0.1551724 | 2.487938 | 2.926228 | 0.0093235 | 0.0343235 | 0.0220654 | COL5A2/CFI/DNAH5/MCIDAS/PSMB8/COL5A1/NFKB2/IL21R/RAC2 | 9 |
| HP_ABNORMAL_PULMONARY_THORACIC_IMAGING_FINDING | HP_ABNORMAL_PULMONARY_THORACIC_IMAGING_FINDING | HP_ABNORMAL_PULMONARY_THORACIC_IMAGING_FINDING | 16/1438 | 134/23056 | 0.1194030 | 1.914433 | 2.737994 | 0.0093611 | 0.0344529 | 0.0221486 | PTPN22/CFAP221/COL3A1/CASP10/SLC34A2/DNAH5/MCIDAS/CCNO/RREB1/DSP/LAMA2/CCN2/CAV1/FAS/BIRC3/APOE | 16 |
| HP_FINGER_CLINODACTYLY | HP_FINGER_CLINODACTYLY | HP_FINGER_CLINODACTYLY | 34/1438 | 357/23056 | 0.0952381 | 1.526989 | 2.588131 | 0.0094485 | 0.0347560 | 0.0223434 | MMP23B/HSPG2/TBX15/WNT5A/CD96/FGFR3/DSP/TFAP2A/RUNX2/GJA1/CITED2/TMEM270/SHH/CSGALNACT1/PLAG1/ZFPM2/TRPS1/FGFR2/HMGA2/IGF1/BMP4/DACT1/SALL1/MAF/JUP/DLX3/NOG/KCNJ2/PIEZO2/GATA6/RRAS/BMP2/GATA5/GPC4 | 34 |
| YOSHIMURA_MAPK8_TARGETS_DN | YOSHIMURA_MAPK8_TARGETS_DN | YOSHIMURA_MAPK8_TARGETS_DN | 34/1438 | 357/23056 | 0.0952381 | 1.526989 | 2.588131 | 0.0094485 | 0.0347560 | 0.0223434 | FUCA1/VCAM1/S100A10/TGFA/HNMT/DPP4/FN1/BHLHE40/PRICKLE2/SLC4A4/NPR3/EDN1/AHR/IL6/TNS3/MET/CEBPD/PTGS1/PAPSS2/ADM/PTPRJ/AHNAK/C1R/EMP1/IGFBP6/FLT1/LTBP2/NUPR1/MYH1/JUP/MYL4/COPZ2/GATA6/CACNA1A | 34 |
| GOBP_KILLING_BY_HOST_OF_SYMBIONT_CELLS | GOBP_KILLING_BY_HOST_OF_SYMBIONT_CELLS | GOBP_KILLING_BY_HOST_OF_SYMBIONT_CELLS | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | CXCL6/F2RL1/MBL2/NLRP6/ELANE/APOL1 | 6 |
| GOBP_MAMMARY_GLAND_DUCT_MORPHOGENESIS | GOBP_MAMMARY_GLAND_DUCT_MORPHOGENESIS | GOBP_MAMMARY_GLAND_DUCT_MORPHOGENESIS | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | EPHA2/CSF1/WNT5A/DDR1/FGFR2/PGR | 6 |
| GOMF_INTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_INTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | GOMF_INTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | MCOLN2/ITPR3/AQP1/TRPA1/TPCN1/HCN4 | 6 |
| GOMF_XENOBIOTIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_XENOBIOTIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | GOMF_XENOBIOTIC_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | ABCG2/SLC22A1/SLC6A13/SLC47A1/ABCC3/ABCA8 | 6 |
| HP_ALOPECIA_OF_SCALP | HP_ALOPECIA_OF_SCALP | HP_ALOPECIA_OF_SCALP | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | ECM1/LAMC2/LAMB3/COL3A1/CLDN1/ITGB4 | 6 |
| HP_HYPOREFLEXIA_OF_LOWER_LIMBS | HP_HYPOREFLEXIA_OF_LOWER_LIMBS | HP_HYPOREFLEXIA_OF_LOWER_LIMBS | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | DES/HSPB3/FLNC/CRYAB/FBLN5/MAG | 6 |
| PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | TNFRSF1B/IER3/HOXA1/IGFBP6/ALOX5AP/TNFAIP2 | 6 |
| TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | FCGR2A/CXCL5/IL7R/TGFBI/ALOX5/LIF | 6 |
| VALK_AML_CLUSTER_12 | VALK_AML_CLUSTER_12 | VALK_AML_CLUSTER_12 | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | GALNT3/NKX3-2/SKAP2/ANXA8/VCL/GABRE | 6 |
| WP_MATRIX_METALLOPROTEINASES | WP_MATRIX_METALLOPROTEINASES | WP_MATRIX_METALLOPROTEINASES | 6/1438 | 30/23056 | 0.2000000 | 3.206676 | 3.119207 | 0.0094872 | 0.0348051 | 0.0223750 | MMP23B/MMP10/MMP1/MMP3/MMP14/MMP2 | 6 |
| GOBP_HORMONE_TRANSPORT | GOBP_HORMONE_TRANSPORT | GOBP_HORMONE_TRANSPORT | 29/1438 | 293/23056 | 0.0989761 | 1.586922 | 2.607674 | 0.0095570 | 0.0350516 | 0.0225335 | C1QTNF12/ILDR2/AGT/IL1B/PPARG/FOXL2/SPP1/DAB2/FOXD1/CRHBP/BMP6/EDN1/HFE/GJA1/IL6/INHBA/ADCY8/ANXA1/ALOX5/TCF7L2/ADM/FZD4/KCNA5/CYP19A1/CCL5/GIP/C1QTNF1/IL11/LIF | 29 |
| GOBP_ANION_HOMEOSTASIS | GOBP_ANION_HOMEOSTASIS | GOBP_ANION_HOMEOSTASIS | 7/1438 | 39/23056 | 0.1794872 | 2.877786 | 3.026971 | 0.0095854 | 0.0351091 | 0.0225704 | CYBRD1/CPS1/SLC12A8/SLC34A2/SLC7A11/SLC12A7/CA12 | 7 |
| HP_DIFFUSE_MESANGIAL_SCLEROSIS | HP_DIFFUSE_MESANGIAL_SCLEROSIS | HP_DIFFUSE_MESANGIAL_SCLEROSIS | 7/1438 | 39/23056 | 0.1794872 | 2.877786 | 3.026971 | 0.0095854 | 0.0351091 | 0.0225704 | LAMB2/ARHGAP24/CRB2/WT1/MYO1E/APOL1/TBC1D8B | 7 |
| ONGUSAHA_TP53_TARGETS | ONGUSAHA_TP53_TARGETS | ONGUSAHA_TP53_TARGETS | 7/1438 | 39/23056 | 0.1794872 | 2.877786 | 3.026971 | 0.0095854 | 0.0351091 | 0.0225704 | TNFRSF18/SERPINE2/ANXA8L1/FAS/NQO1/COL18A1/SAT1 | 7 |
| SESTO_RESPONSE_TO_UV_C6 | SESTO_RESPONSE_TO_UV_C6 | SESTO_RESPONSE_TO_UV_C6 | 7/1438 | 39/23056 | 0.1794872 | 2.877786 | 3.026971 | 0.0095854 | 0.0351091 | 0.0225704 | ITGB5/TGFBI/TPBG/PTGR1/PTGS1/PYGL/RRAS | 7 |
| ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN | ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN | ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN | 7/1438 | 39/23056 | 0.1794872 | 2.877786 | 3.026971 | 0.0095854 | 0.0351091 | 0.0225704 | GFI1/PTPRC/TGFBR2/LEF1/UTRN/MS4A4A/TESPA1 | 7 |
| HP_BOWING_OF_THE_LEGS | HP_BOWING_OF_THE_LEGS | HP_BOWING_OF_THE_LEGS | 23/1438 | 218/23056 | 0.1055046 | 1.691595 | 2.646095 | 0.0096091 | 0.0351864 | 0.0226201 | HSPG2/FN1/SLCO2A1/FGFR3/NKX3-2/SGMS2/RUNX2/TENT5A/TMEM270/CSGALNACT1/TRPS1/EXT1/TPM2/PAPSS2/FGFR2/SERPINH1/GLI1/FBN1/CYP19A1/COL1A1/SOX9/TGFB1/COL9A3 | 23 |
| BASSO_B_LYMPHOCYTE_NETWORK | BASSO_B_LYMPHOCYTE_NETWORK | BASSO_B_LYMPHOCYTE_NETWORK | 17/1438 | 146/23056 | 0.1164384 | 1.866900 | 2.710113 | 0.0096228 | 0.0352179 | 0.0226404 | TNFRSF1B/SP100/BHLHE40/HLA-E/MDFIC/ZYX/SRGN/HHEX/CD44/AHNAK/CASP4/SLC46A3/CRIP1/IL27RA/LGALS1/SAT1/ITM2A | 17 |
| YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | 17/1438 | 146/23056 | 0.1164384 | 1.866900 | 2.710113 | 0.0096228 | 0.0352179 | 0.0226404 | TNFRSF9/BRINP3/HSD11B1/KCNE4/EPHA3/TRPC3/FOXD1/PCSK5/TSPAN32/TRIM5/MPZL2/TNFRSF19/ALDH1A3/NOG/MBP/ADAMTSL5/IL11 | 17 |
| GOBP_ANTIMICROBIAL_HUMORAL_RESPONSE | GOBP_ANTIMICROBIAL_HUMORAL_RESPONSE | GOBP_ANTIMICROBIAL_HUMORAL_RESPONSE | 15/1438 | 123/23056 | 0.1219512 | 1.955290 | 2.739755 | 0.0096594 | 0.0353330 | 0.0227144 | SPON2/JCHAIN/CXCL8/CXCL6/CXCL1/CXCL5/CXCL3/CXCL2/HLA-E/RARRES2/SFTPD/GATA6/ELANE/BCL3/WFDC10B | 15 |
| HP_ABNORMALITY_OF_LIMB_EPIPHYSIS_MORPHOLOGY | HP_ABNORMALITY_OF_LIMB_EPIPHYSIS_MORPHOLOGY | HP_ABNORMALITY_OF_LIMB_EPIPHYSIS_MORPHOLOGY | 15/1438 | 123/23056 | 0.1219512 | 1.955290 | 2.739755 | 0.0096594 | 0.0353330 | 0.0227144 | HSPG2/FN1/WNT5A/FGFRL1/FGFR3/NKX3-2/ADAMTS2/RUNX2/TRPS1/EXT1/SALL1/COL1A1/COL9A3/ARSL/BGN | 15 |
| HP_ABNORMAL_ACETABULUM_MORPHOLOGY | HP_ABNORMAL_ACETABULUM_MORPHOLOGY | HP_ABNORMAL_ACETABULUM_MORPHOLOGY | 11/1438 | 79/23056 | 0.1392405 | 2.232496 | 2.830131 | 0.0097100 | 0.0355086 | 0.0228272 | HSPG2/TGFB2/TGFBR2/FGFR3/TENT5A/CSGALNACT1/FGFR2/FBN1/MMP2/COL1A1/BGN | 11 |
| HP_ABNORMAL_ORAL_PHYSIOLOGY | HP_ABNORMAL_ORAL_PHYSIOLOGY | HP_ABNORMAL_ORAL_PHYSIOLOGY | 25/1438 | 243/23056 | 0.1028807 | 1.649525 | 2.625197 | 0.0097271 | 0.0355616 | 0.0228614 | PTPN22/TGFA/NABP1/EPHA4/LAMB2/FGFR3/SH3TC2/SIM1/LAMA2/CCN2/PON3/SERPINE1/FOXP2/CAV1/TPM2/GSN/FGFR2/PYGM/SCNN1A/WNT10B/ITGA7/SCN1B/FRMPD4/SRPX2/ARHGEF6 | 25 |
| GOBP_REGULATION_OF_ACTIN_FILAMENT_LENGTH | GOBP_REGULATION_OF_ACTIN_FILAMENT_LENGTH | GOBP_REGULATION_OF_ACTIN_FILAMENT_LENGTH | 18/1438 | 158/23056 | 0.1139241 | 1.826588 | 2.688889 | 0.0097865 | 0.0357693 | 0.0229948 | LMOD1/CAPG/SLIT2/SEMA5A/F2RL1/ARHGAP18/SCIN/CCL26/LMOD2/GSN/EPS8/NCKAP1L/COTL1/CSF3/CCR7/CDC42EP5/CDC42EP1/TENM1 | 18 |
| GOCC_CLATHRIN_COATED_VESICLE | GOCC_CLATHRIN_COATED_VESICLE | GOCC_CLATHRIN_COATED_VESICLE | 21/1438 | 194/23056 | 0.1082474 | 1.735572 | 2.653525 | 0.0098338 | 0.0359327 | 0.0230999 | ECE1/LDLRAP1/TGFA/WNT5A/EPGN/EREG/BTC/EGF/IL7R/DAB2/HBEGF/ADRB2/EDN1/ADCY8/SFTPD/FZD4/VWF/MYO1E/WIPI1/APOE/MLC1 | 21 |
| HALLMARK_BILE_ACID_METABOLISM | HALLMARK_BILE_ACID_METABOLISM | HALLMARK_BILE_ACID_METABOLISM | 14/1438 | 112/23056 | 0.1250000 | 2.004173 | 2.747496 | 0.0098805 | 0.0360840 | 0.0231972 | BMP6/CYP39A1/ACSL5/SLC22A18/BBOX1/APOA1/SOAT2/DIO2/SERPINA6/CYP46A1/ABCA8/ABCA9/ABCA6/PEX11G | 14 |
| HP_ENCEPHALOCELE | HP_ENCEPHALOCELE | HP_ENCEPHALOCELE | 14/1438 | 112/23056 | 0.1250000 | 2.004173 | 2.747496 | 0.0098805 | 0.0360840 | 0.0231972 | HSPG2/RPE65/NID1/CYP26B1/FGFR3/SHH/GDF6/GAS1/NOTCH1/ALX4/GRIP1/FREM2/ZIC2/COL18A1 | 14 |
| BOYLAN_MULTIPLE_MYELOMA_D_UP | BOYLAN_MULTIPLE_MYELOMA_D_UP | BOYLAN_MULTIPLE_MYELOMA_D_UP | 12/1438 | 90/23056 | 0.1333333 | 2.137784 | 2.789283 | 0.0099534 | 0.0363212 | 0.0233497 | ITGA6/FSTL1/PLK2/ASPH/ADM/SLC15A3/PRSS23/CPM/SLC47A1/CCR7/BLVRB/CHST7 | 12 |
| GOBP_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM | GOBP_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM | GOBP_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM | 12/1438 | 90/23056 | 0.1333333 | 2.137784 | 2.789283 | 0.0099534 | 0.0363212 | 0.0233497 | IL22RA1/MR1/CXCL6/F2RL1/IL6/AQP1/SERPINE1/RARRES2/DEFB107B/GSDMD/PRKD1/ELANE | 12 |
| GOCC_MICROVILLUS | GOCC_MICROVILLUS | GOCC_MICROVILLUS | 12/1438 | 90/23056 | 0.1333333 | 2.137784 | 2.789283 | 0.0099534 | 0.0363212 | 0.0233497 | VCAM1/IQGAP2/PDGFA/PODXL/ANGPT1/TEK/CD44/PLEKHG6/SLC10A2/MYO1E/TGFB1/MSN | 12 |
| HP_POLYDACTYLY | HP_POLYDACTYLY | HP_POLYDACTYLY | 26/1438 | 256/23056 | 0.1015625 | 1.628390 | 2.607571 | 0.0099639 | 0.0363497 | 0.0233680 | MMP23B/HSPG2/PTCH2/TGFBR2/CD96/FGFRL1/FGFR3/RREB1/TFAP2A/GJA1/GLI3/SHH/PLAG1/GDF6/COLEC10/CRB2/FGFR2/GLI1/HMGA2/ZIC2/BMP4/DACT1/SMAD6/SALL1/GATA6/GPC4 | 26 |
| GOBP_PROTEIN_LOCALIZATION_TO_NUCLEUS | GOBP_PROTEIN_LOCALIZATION_TO_NUCLEUS | GOBP_PROTEIN_LOCALIZATION_TO_NUCLEUS | 29/1438 | 294/23056 | 0.0986395 | 1.581524 | 2.588155 | 0.0099913 | 0.0364401 | 0.0234261 | ZC3H12A/GBP2/PTGS2/RASSF5/AGT/SP100/WWTR1/GLI3/CD36/MDFIC/SHH/ANGPT1/NOTCH1/HHEX/BAG3/YAP1/LATS2/PRKD1/NFKBIA/BMP4/SIX1/SIX4/JUP/COL1A1/SOX9/TGFB1/BCL3/LIF/CARD10 | 29 |
| GAVIN_PDE3B_TARGETS | GAVIN_PDE3B_TARGETS | GAVIN_PDE3B_TARGETS | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | TFPI/NT5E/SYTL2/EBI3/TGFB1 | 5 |
| GOBP_CALCIUM_MEDIATED_SIGNALING_USING_INTRACELLULAR_CALCIUM_SOURCE | GOBP_CALCIUM_MEDIATED_SIGNALING_USING_INTRACELLULAR_CALCIUM_SOURCE | GOBP_CALCIUM_MEDIATED_SIGNALING_USING_INTRACELLULAR_CALCIUM_SOURCE | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | VCAM1/PTPRC/KDR/PTPRJ/PRNP | 5 |
| GOBP_GLYCEROL_ETHER_METABOLIC_PROCESS | GOBP_GLYCEROL_ETHER_METABOLIC_PROCESS | GOBP_GLYCEROL_ETHER_METABOLIC_PROCESS | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | PLA2G4A/PLA2G7/PLAAT3/LPCAT2/PLA2G4C | 5 |
| GOBP_LYMPHOID_PROGENITOR_CELL_DIFFERENTIATION | GOBP_LYMPHOID_PROGENITOR_CELL_DIFFERENTIATION | GOBP_LYMPHOID_PROGENITOR_CELL_DIFFERENTIATION | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | HES1/SHH/NOTCH1/FLT3/BMP4 | 5 |
| GOBP_NEGATIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_NEGATIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_NEGATIVE_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | HEG1/BCL6/MET/ARHGAP42/ITGA3 | 5 |
| GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | GOBP_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | DKK1/BMP4/MYOCD/TGFB1/BMP2 | 5 |
| GOBP_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS | GOBP_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS | GOBP_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | GFI1/DAB2/BMP6/ADM/BMP2 | 5 |
| GOBP_REGULATION_OF_ICOSANOID_SECRETION | GOBP_REGULATION_OF_ICOSANOID_SECRETION | GOBP_REGULATION_OF_ICOSANOID_SECRETION | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | PLA2G4A/IL1A/IL1B/EDN1/TNFRSF11A | 5 |
| GOBP_REGULATION_OF_RESPONSE_TO_TUMOR_CELL | GOBP_REGULATION_OF_RESPONSE_TO_TUMOR_CELL | GOBP_REGULATION_OF_RESPONSE_TO_TUMOR_CELL | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | MR1/AHR/CD274/NECTIN2/IL4I1 | 5 |
| GOBP_SEX_DETERMINATION | GOBP_SEX_DETERMINATION | GOBP_SEX_DETERMINATION | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | FOXL2/CITED2/WT1/SIX4/SOX9 | 5 |
| GOBP_VASCULAR_WOUND_HEALING | GOBP_VASCULAR_WOUND_HEALING | GOBP_VASCULAR_WOUND_HEALING | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | CD34/KDR/TNFAIP3/SERPINE1/ALOX5 | 5 |
| HP_ABNORMAL_SERUM_INTERFERON_LEVEL | HP_ABNORMAL_SERUM_INTERFERON_LEVEL | HP_ABNORMAL_SERUM_INTERFERON_LEVEL | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | PTPN22/SP110/PSMB8/STX11/IL2RB | 5 |
| HP_ABNORMALITY_OF_METACARPOPHALANGEAL_JOINT | HP_ABNORMALITY_OF_METACARPOPHALANGEAL_JOINT | HP_ABNORMALITY_OF_METACARPOPHALANGEAL_JOINT | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | PTPN22/COL3A1/HFE/NOG/IL2RB | 5 |
| HP_ECTOPIA_PUPILLAE | HP_ECTOPIA_PUPILLAE | HP_ECTOPIA_PUPILLAE | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | ADAMTSL4/FGFRL1/FOXC1/WT1/FBN1 | 5 |
| HP_NEOPLASM_OF_THE_TRACHEOBRONCHIAL_SYSTEM | HP_NEOPLASM_OF_THE_TRACHEOBRONCHIAL_SYSTEM | HP_NEOPLASM_OF_THE_TRACHEOBRONCHIAL_SYSTEM | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | CASP8/MAP3K8/SLC22A18/COL4A6/COL4A5 | 5 |
| HP_PROGRESSIVE_PROXIMAL_MUSCLE_WEAKNESS | HP_PROGRESSIVE_PROXIMAL_MUSCLE_WEAKNESS | HP_PROGRESSIVE_PROXIMAL_MUSCLE_WEAKNESS | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | COL6A3/COL12A1/PYGM/CRYAB/COL6A2 | 5 |
| PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | NR5A2/GYPA/EXT1/ADCY8/MICAL2 | 5 |
| WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC | WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC | WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | EREG/ARHGAP24/COL5A1/BMF/LPAR4 | 5 |
| WP_TRANSCRIPTION_FACTOR_REGULATION_IN_ADIPOGENESIS | WP_TRANSCRIPTION_FACTOR_REGULATION_IN_ADIPOGENESIS | WP_TRANSCRIPTION_FACTOR_REGULATION_IN_ADIPOGENESIS | 5/1438 | 22/23056 | 0.2272727 | 3.643950 | 3.199883 | 0.0101161 | 0.0367101 | 0.0235996 | PPARG/IL6/CEBPD/FOXO1/CEBPB | 5 |
| GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | GOBP_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 10/1438 | 69/23056 | 0.1449275 | 2.323678 | 2.840011 | 0.0101684 | 0.0368665 | 0.0237002 | NLRP3/IL1R1/IL1B/WNT5A/SPON2/F2RL1/HLA-E/IL6/CD36/DDX58 | 10 |
| GOBP_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY | GOBP_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY | 10/1438 | 69/23056 | 0.1449275 | 2.323678 | 2.840011 | 0.0101684 | 0.0368665 | 0.0237002 | CCN1/RHOC/AGT/FGFR3/TXK/FGFR2/APOA1/FLT1/CCL5/C5AR1 | 10 |
| HP_ABNORMALITY_OF_THE_HEPATIC_VASCULATURE | HP_ABNORMALITY_OF_THE_HEPATIC_VASCULATURE | HP_ABNORMALITY_OF_THE_HEPATIC_VASCULATURE | 10/1438 | 69/23056 | 0.1449275 | 2.323678 | 2.840011 | 0.0101684 | 0.0368665 | 0.0237002 | ACTG2/SP110/CLDN1/HFE/GLIS3/TNFSF15/NOTCH1/FLT1/IL12RB1/RUNX1 | 10 |
| HP_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | HP_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | HP_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | 41/1438 | 451/23056 | 0.0909091 | 1.457580 | 2.531088 | 0.0101700 | 0.0368665 | 0.0237002 | MMP23B/HSPG2/TBX15/WNT5A/CD96/FGFR3/DOK7/DSP/TFAP2A/RUNX2/GJA1/CITED2/ADGRG6/GLI3/TMEM270/SAMD9/SHH/CSGALNACT1/PLAG1/ZFPM2/TRPS1/TPM2/FGFR2/HMGA2/IGF1/BMP4/DACT1/SALL1/MAF/JUP/DLX3/NOG/KCNJ2/PIEZO2/GATA6/RRAS/BMP2/GATA5/COL9A3/GPC4/BGN | 41 |
| GOBP_COCHLEA_DEVELOPMENT | GOBP_COCHLEA_DEVELOPMENT | GOBP_COCHLEA_DEVELOPMENT | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | EPHA4/WNT5A/HES1/TBX18/HOXA1/CTHRC1/SIX1/SOX9 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS | GOBP_NEGATIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | ZC3H12A/EDN1/BAG3/IGF1/NUPR1/MYOCD/LYPD3/HMOX1 | 8 |
| GOBP_POSITIVE_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | GOBP_POSITIVE_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | GOBP_POSITIVE_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_STAT | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | AGT/HES1/IL7R/TSLP/IL6/NOTCH1/CCL5/TGFB1 | 8 |
| GOBP_PROTEIN_LIPID_COMPLEX_SUBUNIT_ORGANIZATION | GOBP_PROTEIN_LIPID_COMPLEX_SUBUNIT_ORGANIZATION | GOBP_PROTEIN_LIPID_COMPLEX_SUBUNIT_ORGANIZATION | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | AGT/PLA2G7/APOC3/APOA1/SOAT2/CETP/LIPG/APOE | 8 |
| GOMF_TUMOR_NECROSIS_FACTOR_RECEPTOR_SUPERFAMILY_BINDING | GOMF_TUMOR_NECROSIS_FACTOR_RECEPTOR_SUPERFAMILY_BINDING | GOMF_TUMOR_NECROSIS_FACTOR_RECEPTOR_SUPERFAMILY_BINDING | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | TNFSF18/CASP8/TNFSF15/TRAF1/TNFSF13B/TNFSF9/CD70/TNFSF14 | 8 |
| HP_ABNORMAL_MACROSCOPIC_URINE_APPEARANCE | HP_ABNORMAL_MACROSCOPIC_URINE_APPEARANCE | HP_ABNORMAL_MACROSCOPIC_URINE_APPEARANCE | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | ARHGAP24/SPP1/CRB2/WT1/PYGM/MYO1E/APOL1/TBC1D8B | 8 |
| HP_BICORNUATE_UTERUS | HP_BICORNUATE_UTERUS | HP_BICORNUATE_UTERUS | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | RARB/FGFR3/ITGA8/FGFR2/WT1/GRIP1/FREM2/FOXF1 | 8 |
| PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | 8/1438 | 49/23056 | 0.1632653 | 2.617695 | 2.923606 | 0.0102867 | 0.0372110 | 0.0239217 | FN1/DOK2/ANGPT1/TEK/ITGA5/FOXO1/MMP2/GRB7 | 8 |
| GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | GOBP_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 15/1438 | 124/23056 | 0.1209677 | 1.939522 | 2.705521 | 0.0103743 | 0.0375179 | 0.0241190 | ARHGEF16/EPHA2/LDLRAP1/GBP1/ATP2B4/LYPD1/EPHA3/LRRC15/NKD2/DAB2/MMP14/ITGA3/TGFB1/PRNP/GPC4 | 15 |
| DAWSON_METHYLATED_IN_LYMPHOMA_TCL1 | DAWSON_METHYLATED_IN_LYMPHOMA_TCL1 | DAWSON_METHYLATED_IN_LYMPHOMA_TCL1 | 9/1438 | 59/23056 | 0.1525424 | 2.445770 | 2.867767 | 0.0104090 | 0.0375843 | 0.0241616 | PCDH10/FOXC1/ID4/TBX18/HOXA2/TNS3/CADPS2/GAS1/TNFAIP2 | 9 |
| GOBP_ACTIN_FILAMENT_DEPOLYMERIZATION | GOBP_ACTIN_FILAMENT_DEPOLYMERIZATION | GOBP_ACTIN_FILAMENT_DEPOLYMERIZATION | 9/1438 | 59/23056 | 0.1525424 | 2.445770 | 2.867767 | 0.0104090 | 0.0375843 | 0.0241616 | LMOD1/CAPG/SEMA5A/F2RL1/SCIN/LMOD2/GSN/MICAL2/EPS8 | 9 |
| GOBP_NEURON_PROJECTION_REGENERATION | GOBP_NEURON_PROJECTION_REGENERATION | GOBP_NEURON_PROJECTION_REGENERATION | 9/1438 | 59/23056 | 0.1525424 | 2.445770 | 2.867767 | 0.0104090 | 0.0375843 | 0.0241616 | PRRX1/EPHA4/LAMB2/SPP1/PTN/KLF4/ADM/MMP2/MAG | 9 |
| GOBP_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | GOBP_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | GOBP_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY | 9/1438 | 59/23056 | 0.1525424 | 2.445770 | 2.867767 | 0.0104090 | 0.0375843 | 0.0241616 | MR1/PTPRC/NLRP3/IL1R1/IL1B/HLA-E/IL6/IL12RB1/NECTIN2 | 9 |
| HP_ABNORMAL_TRICUSPID_VALVE_PHYSIOLOGY | HP_ABNORMAL_TRICUSPID_VALVE_PHYSIOLOGY | HP_ABNORMAL_TRICUSPID_VALVE_PHYSIOLOGY | 9/1438 | 59/23056 | 0.1525424 | 2.445770 | 2.867767 | 0.0104090 | 0.0375843 | 0.0241616 | PLD1/CITED2/FLNC/CSGALNACT1/MYPN/ACTC1/FBN1/ALPK3/GATA6 | 9 |
| HP_SPARSE_AND_THIN_EYEBROW | HP_SPARSE_AND_THIN_EYEBROW | HP_SPARSE_AND_THIN_EYEBROW | 9/1438 | 59/23056 | 0.1525424 | 2.445770 | 2.867767 | 0.0104090 | 0.0375843 | 0.0241616 | TWIST2/CLDN1/DSP/TRPS1/ALX4/KRT17/JUP/ITGA3/RIN2 | 9 |
| REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS | REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS | REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS | 29/1438 | 295/23056 | 0.0983051 | 1.576163 | 2.568708 | 0.0104416 | 0.0376920 | 0.0242309 | DHRS3/CRABP2/NR5A2/TGFA/CYP26B1/RARB/EPGN/EREG/BTC/EGF/HBEGF/H3C6/PDK4/CAV2/CAV1/S1PR3/AKR1C3/CYP26A1/PGR/MMP3/H2AJ/FOS/ALDH1A2/ALDH1A3/MMP2/CETP/GNGT2/APOE/RUNX1 | 29 |
| GOBP_IMPORT_INTO_CELL | GOBP_IMPORT_INTO_CELL | GOBP_IMPORT_INTO_CELL | 24/1438 | 232/23056 | 0.1034483 | 1.658626 | 2.600404 | 0.0104496 | 0.0377109 | 0.0242431 | SLC1A7/ATP2B4/AGT/CYBRD1/ITGA4/SLC12A8/SLC7A11/SLC12A7/GDNF/HFE/SLC22A1/CD36/ACSL5/SLC15A3/SLC6A13/SCNN1A/SPX/SLC24A4/THBS1/HCN4/TRPV2/SLC47A1/KCNJ2/PRNP | 24 |
| HP_BROAD_FOREHEAD | HP_BROAD_FOREHEAD | HP_BROAD_FOREHEAD | 19/1438 | 171/23056 | 0.1111111 | 1.781487 | 2.645443 | 0.0104723 | 0.0377827 | 0.0242892 | ACTG2/FGFR3/ADAMTS3/FAT4/RUNX2/TENT5A/SIM1/CITED2/TMEM270/ZFPM2/FGFR2/ZIC2/FBN1/RNF135/KCNJ2/GATA6/BMP2/GATA5/GPC4 | 19 |
| FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN | FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN | FONTAINE_PAPILLARY_THYROID_CARCINOMA_DN | 11/1438 | 80/23056 | 0.1375000 | 2.204590 | 2.783564 | 0.0106416 | 0.0383333 | 0.0246432 | RUNX3/CD34/MLPH/IGSF10/SH3RF2/GFPT2/MATN2/CD274/KLRD1/JUP/ABCA8 | 11 |
| GOBP_PROTEOGLYCAN_METABOLIC_PROCESS | GOBP_PROTEOGLYCAN_METABOLIC_PROCESS | GOBP_PROTEOGLYCAN_METABOLIC_PROCESS | 11/1438 | 80/23056 | 0.1375000 | 2.204590 | 2.783564 | 0.0106416 | 0.0383333 | 0.0246432 | ADAMTS12/CHSY3/UST/CSGALNACT1/SULF1/EXT1/TCF7L2/IGF1/BMP2/CHST7/BGN | 11 |
| HP_DIPLOPIA | HP_DIPLOPIA | HP_DIPLOPIA | 11/1438 | 80/23056 | 0.1375000 | 2.204590 | 2.783564 | 0.0106416 | 0.0383333 | 0.0246432 | AGRN/PTPN22/DOK7/PODXL/DKK1/COL13A1/NFKB2/STAT6/CACNA1A/TGFB1/PRNP | 11 |
| HP_MUSCULAR_DYSTROPHY | HP_MUSCULAR_DYSTROPHY | HP_MUSCULAR_DYSTROPHY | 11/1438 | 80/23056 | 0.1375000 | 2.204590 | 2.783564 | 0.0106416 | 0.0383333 | 0.0246432 | COL6A3/COL12A1/LAMA2/BAG3/CRYAB/ITGA7/CAVIN1/SGCA/ITGB4/PIEZO2/COL6A2 | 11 |
| ROSS_AML_WITH_PML_RARA_FUSION | ROSS_AML_WITH_PML_RARA_FUSION | ROSS_AML_WITH_PML_RARA_FUSION | 11/1438 | 80/23056 | 0.1375000 | 2.204590 | 2.783564 | 0.0106416 | 0.0383333 | 0.0246432 | AGRN/TNFRSF4/STAB1/FNDC3B/AQP3/ALOX5/ANXA8/KRT18/LTK/MMP2/MRC2 | 11 |
| YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | 11/1438 | 80/23056 | 0.1375000 | 2.204590 | 2.783564 | 0.0106416 | 0.0383333 | 0.0246432 | CAVIN2/LAMA2/AQP1/RARRES2/CA3/ADM/TNS2/FLT1/APOE/THBD/REM1 | 11 |
| GOMF_RNA_POLYMERASE_II_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_BINDING | GOMF_RNA_POLYMERASE_II_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_BINDING | GOMF_RNA_POLYMERASE_II_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_BINDING | 33/1438 | 347/23056 | 0.0951009 | 1.524788 | 2.540412 | 0.0106519 | 0.0383601 | 0.0246604 | PRRX1/CD34/BHLHE40/PPARG/FOXL2/HES1/LEF1/ZNF366/STING1/FOXC1/ID4/CITED2/AHR/TRIP6/MDFIC/ZFPM2/KLF4/ANKRD1/TCF7L2/BHLHE41/HMGA2/GRIP1/OASL/FLT3/NFKBIA/DACT1/FOS/ESRRB/MYOCD/WIPI1/GATA6/CEBPB/GAS2L1 | 33 |
| WP_TCELL_RECEPTOR_TCR_SIGNALING_PATHWAY | WP_TCELL_RECEPTOR_TCR_SIGNALING_PATHWAY | WP_TCELL_RECEPTOR_TCR_SIGNALING_PATHWAY | 12/1438 | 91/23056 | 0.1318681 | 2.114292 | 2.746886 | 0.0108337 | 0.0390047 | 0.0250748 | TNFRSF9/IL1A/IL1B/IL6/IL15RA/MAP3K8/FAS/NFKBIA/FOS/LAT/TGFB1/NFATC2 | 12 |
| HP_ABNORMALITY_OF_FEMUR_MORPHOLOGY | HP_ABNORMALITY_OF_FEMUR_MORPHOLOGY | HP_ABNORMALITY_OF_FEMUR_MORPHOLOGY | 26/1438 | 258/23056 | 0.1007752 | 1.615767 | 2.565264 | 0.0109526 | 0.0394224 | 0.0253433 | HSPG2/FUCA1/TBX15/PRG4/FN1/WNT5A/FGFR3/NKX3-2/SGMS2/ADAMTS2/RUNX2/TENT5A/GJA1/GLI3/CSGALNACT1/TRPS1/EXT1/FGFR2/FBN1/COL1A1/SOX9/TNFRSF11A/TGFB1/COL9A3/ARSL/BGN | 26 |
| GOBP_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | GOBP_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | GOBP_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | 21/1438 | 196/23056 | 0.1071429 | 1.717862 | 2.603066 | 0.0109784 | 0.0394884 | 0.0253858 | LMOD1/CAPG/CATIP/SLIT2/SEMA5A/F2RL1/ARHGAP18/MICALL2/SCIN/CCL26/LMOD2/GSN/MICAL2/EPS8/NCKAP1L/COTL1/CSF3/CCR7/CDC42EP5/CDC42EP1/TENM1 | 21 |
| HP_SYNDACTYLY | HP_SYNDACTYLY | HP_SYNDACTYLY | 36/1438 | 387/23056 | 0.0930233 | 1.491477 | 2.514762 | 0.0109868 | 0.0394884 | 0.0253858 | TBX15/TWIST2/TGFBR2/WNT5A/CD96/FGFR3/ADAMTS3/FAT4/SEMA5A/DSP/GJA1/GLI3/SHH/CSGALNACT1/PLAG1/NOTCH1/FGFR2/WNT10B/HMGA2/GRIP1/FREM2/PRKD1/BMP4/DACT1/SMAD6/SALL1/MYH8/JUP/NOG/KCNJ2/ITGB4/PIEZO2/BMP2/FRMPD4/GPC4/ARHGEF6 | 36 |
| CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 30/1438 | 309/23056 | 0.0970874 | 1.556639 | 2.540650 | 0.0109935 | 0.0394884 | 0.0253858 | ATP2B4/HNMT/BHLHE40/DOK7/ITGA2/SPARC/RBM24/TPBG/BMPER/STC1/ZNF703/MYBL1/SULF1/COL5A1/PAPSS2/BAG3/PRSS23/PGR/ADAMTS15/YBX3/FREM2/CA12/MT2A/MRC2/RHBDF2/IL27RA/EMP3/TFAP2C/PNPLA3/COL4A5 | 30 |
| CERIBELLI_PROMOTERS_INACTIVE_AND_BOUND_BY_NFY | CERIBELLI_PROMOTERS_INACTIVE_AND_BOUND_BY_NFY | CERIBELLI_PROMOTERS_INACTIVE_AND_BOUND_BY_NFY | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | CYP24A1/DOK5/MAP3K7CL/CLIC6/MX1/IL2RB/APOBEC3A | 7 |
| GOBP_CELLULAR_RESPONSE_TO_OSMOTIC_STRESS | GOBP_CELLULAR_RESPONSE_TO_OSMOTIC_STRESS | GOBP_CELLULAR_RESPONSE_TO_OSMOTIC_STRESS | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | ERRFI1/PTGS2/MYLK/AQP1/YBX3/ZFP36L1/RELB | 7 |
| GOBP_HIPPO_SIGNALING | GOBP_HIPPO_SIGNALING | GOBP_HIPPO_SIGNALING | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | AMOTL2/WWTR1/FAT4/YAP1/LATS2/AJUBA/WTIP | 7 |
| GOBP_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION | GOBP_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION | GOBP_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | EDN2/TGFB2/EDN1/CCN2/ADM/TPM1/ADRA1D | 7 |
| GOBP_REGULATION_OF_CELLULAR_EXTRAVASATION | GOBP_REGULATION_OF_CELLULAR_EXTRAVASATION | GOBP_REGULATION_OF_CELLULAR_EXTRAVASATION | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | IL1R1/ITGA4/ELANE/ICAM1/IL27RA/PLVAP/XG | 7 |
| HP_ABNORMALITY_OF_THE_ALVEOLAR_RIDGES | HP_ABNORMALITY_OF_THE_ALVEOLAR_RIDGES | HP_ABNORMALITY_OF_THE_ALVEOLAR_RIDGES | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | TBX15/CD96/GJA1/C1S/C1R/ELANE/GPC4 | 7 |
| HP_BROAD_PHALANX_OF_THE_TOES | HP_BROAD_PHALANX_OF_THE_TOES | HP_BROAD_PHALANX_OF_THE_TOES | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | GLI3/FGFR2/DACT1/SALL1/SCN1B/BMP2/GPC4 | 7 |
| HP_ORAL_ULCER | HP_ORAL_ULCER | HP_ORAL_ULCER | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | GFI1/PTPRC/SPP1/IL7R/TNFAIP3/FAS/ELANE | 7 |
| WENG_POR_TARGETS_LIVER_UP | WENG_POR_TARGETS_LIVER_UP | WENG_POR_TARGETS_LIVER_UP | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | AHR/CD36/CYP26A1/GADD45B/PRNP/HMOX1/LGALS1 | 7 |
| ZHAN_MULTIPLE_MYELOMA_LB_DN | ZHAN_MULTIPLE_MYELOMA_LB_DN | ZHAN_MULTIPLE_MYELOMA_LB_DN | 7/1438 | 40/23056 | 0.1750000 | 2.805841 | 2.948146 | 0.0110083 | 0.0394884 | 0.0253858 | RTP4/DDX60/CASP4/PSMB10/IFI35/MX2/USP18 | 7 |
| ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | ASTON_MAJOR_DEPRESSIVE_DISORDER_DN | 18/1438 | 160/23056 | 0.1125000 | 1.803755 | 2.631226 | 0.0110700 | 0.0396942 | 0.0255181 | TMEM63A/CAP2/MOG/SYNJ2/SEMA3C/GPR37/FGFR2/MYRF/CRYAB/CYP19A1/MYO1E/ACSM3/ABCA8/MAG/KLK6/MX1/CDC42EP1/COL4A5 | 18 |
| GOBP_CYTOSOLIC_CALCIUM_ION_TRANSPORT | GOBP_CYTOSOLIC_CALCIUM_ION_TRANSPORT | GOBP_CYTOSOLIC_CALCIUM_ION_TRANSPORT | 20/1438 | 184/23056 | 0.1086957 | 1.742759 | 2.608908 | 0.0110715 | 0.0396942 | 0.0255181 | MCOLN2/CASQ1/PTPRC/ATP2B4/TRPC3/ITPR3/TRDN/CCN2/CAV1/TRPA1/UBASH3B/TPCN1/PRKD1/SLC24A4/BDKRB1/TRPV2/CCR7/HAP1/PRNP/JPH2 | 20 |
| RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | 15/1438 | 125/23056 | 0.1200000 | 1.924006 | 2.671606 | 0.0111301 | 0.0398553 | 0.0256216 | COL3A1/COL5A2/LRRC15/CARD6/PPIC/GALNT10/ADAMTS2/MAFK/SYTL2/CPM/FBN1/KDELR3/MXRA5/SRPX2/IL13RA1 | 15 |
| BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_DN | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | PDGFRL/FABP4/IGF1/SOCS3/C3/APOE | 6 |
| BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | PTPN22/SPP1/SLC7A11/SERPINB1/RAB20/SAT1 | 6 |
| DANG_MYC_TARGETS_DN | DANG_MYC_TARGETS_DN | DANG_MYC_TARGETS_DN | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | SERPINE1/ZFP36L1/TGFB1/HMOX1/PDGFB/MSN | 6 |
| GOBP_ANGIOGENESIS_INVOLVED_IN_WOUND_HEALING | GOBP_ANGIOGENESIS_INVOLVED_IN_WOUND_HEALING | GOBP_ANGIOGENESIS_INVOLVED_IN_WOUND_HEALING | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | CD34/KDR/TNFAIP3/SERPINE1/B4GALT1/ALOX5 | 6 |
| GOBP_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | GOBP_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ORGANIZATION | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | S100A10/KDR/TEK/NRP1/PTPRJ/SDC4 | 6 |
| GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | GOBP_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | ZC3H12A/PTPN22/STING1/DDX58/IL12RB1/APOBEC3G | 6 |
| GOBP_RESPONSE_TO_INTERFERON_BETA | GOBP_RESPONSE_TO_INTERFERON_BETA | GOBP_RESPONSE_TO_INTERFERON_BETA | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | IFI16/IKBKE/TLR3/STING1/IFITM2/IFITM3 | 6 |
| GOBP_TOLERANCE_INDUCTION | GOBP_TOLERANCE_INDUCTION | GOBP_TOLERANCE_INDUCTION | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | TGFBR2/HLA-E/TNFAIP3/IDO1/CD274/PSG9 | 6 |
| HP_ABNORMALITY_OF_DENTAL_COLOR | HP_ABNORMALITY_OF_DENTAL_COLOR | HP_ABNORMALITY_OF_DENTAL_COLOR | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | ITGB6/ENAM/TENT5A/DLX3/KCNJ2/ITGB4 | 6 |
| HP_AMELOGENESIS_IMPERFECTA | HP_AMELOGENESIS_IMPERFECTA | HP_AMELOGENESIS_IMPERFECTA | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | LAMB3/ITGB6/AMTN/ENAM/SLC24A4/DLX3 | 6 |
| HP_MUSCLE_FIBER_INCLUSION_BODIES | HP_MUSCLE_FIBER_INCLUSION_BODIES | HP_MUSCLE_FIBER_INCLUSION_BODIES | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | CASQ1/FLNC/TPM2/MYPN/CRYAB/MYH2 | 6 |
| HP_NATAL_TOOTH | HP_NATAL_TOOTH | HP_NATAL_TOOTH | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | DSP/FAM20C/GLI3/FGFR2/KRT17/JUP | 6 |
| REACTOME_HS_GAG_BIOSYNTHESIS | REACTOME_HS_GAG_BIOSYNTHESIS | REACTOME_HS_GAG_BIOSYNTHESIS | 6/1438 | 31/23056 | 0.1935484 | 3.103235 | 3.022199 | 0.0111570 | 0.0398553 | 0.0256216 | AGRN/HSPG2/EXT1/HS3ST3A1/SDC4/GPC4 | 6 |
| HP_NEOPLASM_OF_THE_RESPIRATORY_SYSTEM | HP_NEOPLASM_OF_THE_RESPIRATORY_SYSTEM | HP_NEOPLASM_OF_THE_RESPIRATORY_SYSTEM | 10/1438 | 70/23056 | 0.1428571 | 2.290483 | 2.788841 | 0.0112188 | 0.0400550 | 0.0257500 | CASP8/SLCO2A1/PERP/COL14A1/MAP3K8/SLC22A18/WT1/STAT6/COL4A6/COL4A5 | 10 |
| SESTO_RESPONSE_TO_UV_C7 | SESTO_RESPONSE_TO_UV_C7 | SESTO_RESPONSE_TO_UV_C7 | 10/1438 | 70/23056 | 0.1428571 | 2.290483 | 2.788841 | 0.0112188 | 0.0400550 | 0.0257500 | CRABP2/PLA2G4A/ITGA6/CEBPD/GSN/MMP10/MMP1/MT1X/LIF/LGALS1 | 10 |
| HP_TALL_STATURE | HP_TALL_STATURE | HP_TALL_STATURE | 22/1438 | 209/23056 | 0.1052632 | 1.687724 | 2.575889 | 0.0114226 | 0.0407719 | 0.0262109 | HSPG2/TGFB2/COL6A3/PPARG/TGFBR2/MYLK/FGFR3/GLI3/CAV1/TPM2/MYPN/EFEMP2/C1R/FOS/FBLN5/FBN1/CYP19A1/RNF135/CAVIN1/TGFB1/COL6A2/GPC4 | 22 |
| HP_ABNORMAL_FEMORAL_NECK_MORPHOLOGY | HP_ABNORMAL_FEMORAL_NECK_MORPHOLOGY | HP_ABNORMAL_FEMORAL_NECK_MORPHOLOGY | 16/1438 | 137/23056 | 0.1167883 | 1.872512 | 2.641726 | 0.0114596 | 0.0408828 | 0.0262822 | HSPG2/FUCA1/PRG4/FN1/WNT5A/FGFR3/NKX3-2/ADAMTS2/RUNX2/GLI3/CSGALNACT1/EXT1/COL1A1/TGFB1/COL9A3/BGN | 16 |
| HP_INTRACRANIAL_HEMORRHAGE | HP_INTRACRANIAL_HEMORRHAGE | HP_INTRACRANIAL_HEMORRHAGE | 16/1438 | 137/23056 | 0.1167883 | 1.872512 | 2.641726 | 0.0114596 | 0.0408828 | 0.0262822 | CFH/TGFB2/COL3A1/FN1/TGFBR2/MYLK/CFI/ITGA2/SPARC/CD109/TENT5A/SAMD9/SERPINE1/FBN1/USP18/PDGFB | 16 |
| MATZUK_SPERMATOZOA | MATZUK_SPERMATOZOA | MATZUK_SPERMATOZOA | 14/1438 | 114/23056 | 0.1228070 | 1.969011 | 2.674977 | 0.0114654 | 0.0408930 | 0.0262887 | ADCY10/ATP2B4/CFAP221/ADAD1/ADAMTS2/ROS1/AHR/WIPF3/B4GALT1/MFGE8/TGFB1/NECTIN2/PLA2G4C/PRND | 14 |
| GOBP_STEROID_METABOLIC_PROCESS | GOBP_STEROID_METABOLIC_PROCESS | GOBP_STEROID_METABOLIC_PROCESS | 31/1438 | 323/23056 | 0.0959752 | 1.538807 | 2.515131 | 0.0115168 | 0.0410548 | 0.0263927 | LDLRAP1/GFI1/NR5A2/HSD11B1/AGT/SRD5A2/CYP26B1/IL1A/UGT2B7/SULT1E1/SPP1/DAB2/BMP6/CYP39A1/AKR1B15/SHH/AKR1C3/CYP26A1/ADM/APOA1/SOAT2/EDNRB/SERPINA6/CYP46A1/CYP19A1/CES1/CETP/APOE/BMP2/CYP24A1/APOL1 | 31 |
| GRESHOCK_CANCER_COPY_NUMBER_UP | GRESHOCK_CANCER_COPY_NUMBER_UP | GRESHOCK_CANCER_COPY_NUMBER_UP | 31/1438 | 323/23056 | 0.0959752 | 1.538807 | 2.515131 | 0.0115168 | 0.0410548 | 0.0263927 | PRRX1/ACKR3/PPARG/BCL6/LPP/FGFR3/TEC/ROS1/MET/PLAG1/EXT1/NOTCH1/FAS/NFKB2/FGFR2/WT1/MAML2/BIRC3/HMGA2/FLT3/FOXO1/LCP1/IL21R/MAF/COL1A1/FSTL3/BCL3/RUNX1/MN1/MYH9/PDGFB | 31 |
| GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | GOBP_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY | 9/1438 | 60/23056 | 0.1500000 | 2.405007 | 2.810491 | 0.0115869 | 0.0412344 | 0.0265082 | CXCL6/F2RL1/HLA-E/DDX58/IL4R/FOXF1/C3/HMOX1/RAC2 | 9 |
| HP_CUTANEOUS_SYNDACTYLY | HP_CUTANEOUS_SYNDACTYLY | HP_CUTANEOUS_SYNDACTYLY | 9/1438 | 60/23056 | 0.1500000 | 2.405007 | 2.810491 | 0.0115869 | 0.0412344 | 0.0265082 | FAT4/GJA1/GLI3/FGFR2/GRIP1/FREM2/MYH8/NOG/PIEZO2 | 9 |
| GOBP_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | GOBP_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | GOBP_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 8/1438 | 50/23056 | 0.1600000 | 2.565341 | 2.857772 | 0.0115942 | 0.0412344 | 0.0265082 | SP100/TNFAIP3/SERPINE1/ITPRIP/THBS1/TMC8/ICAM1/HMOX1 | 8 |
| HP_ABNORMAL_CRY | HP_ABNORMAL_CRY | HP_ABNORMAL_CRY | 8/1438 | 50/23056 | 0.1600000 | 2.565341 | 2.857772 | 0.0115942 | 0.0412344 | 0.0265082 | AGRN/LAMB2/SEMA5A/SIM1/LAMA2/TPM2/COL13A1/CRYAB | 8 |
| HP_ABNORMAL_NUMBER_OF_INCISORS | HP_ABNORMAL_NUMBER_OF_INCISORS | HP_ABNORMAL_NUMBER_OF_INCISORS | 8/1438 | 50/23056 | 0.1600000 | 2.565341 | 2.857772 | 0.0115942 | 0.0412344 | 0.0265082 | TGFA/SHH/GAS1/WNT10B/ZIC2/BMP4/DLX4/DLX3 | 8 |
| HP_NARROW_NASAL_BRIDGE | HP_NARROW_NASAL_BRIDGE | HP_NARROW_NASAL_BRIDGE | 8/1438 | 50/23056 | 0.1600000 | 2.565341 | 2.857772 | 0.0115942 | 0.0412344 | 0.0265082 | COL3A1/SIM1/GJA1/SHH/GAS1/ZIC2/MMP2/NDP | 8 |
| HP_PULMONARY_INFILTRATES | HP_PULMONARY_INFILTRATES | HP_PULMONARY_INFILTRATES | 8/1438 | 50/23056 | 0.1600000 | 2.565341 | 2.857772 | 0.0115942 | 0.0412344 | 0.0265082 | PTPN22/CASP10/SLC34A2/CCN2/CAV1/FAS/BIRC3/APOE | 8 |
| REACTOME_SIGNALING_BY_EGFR | REACTOME_SIGNALING_BY_EGFR | REACTOME_SIGNALING_BY_EGFR | 8/1438 | 50/23056 | 0.1600000 | 2.565341 | 2.857772 | 0.0115942 | 0.0412344 | 0.0265082 | TGFA/EPGN/EREG/BTC/EGF/HBEGF/PTPRK/PTPN3 | 8 |
| WP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY | WP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY | WP_INTERLEUKIN1_IL1_STRUCTURAL_PATHWAY | 8/1438 | 50/23056 | 0.1600000 | 2.565341 | 2.857772 | 0.0115942 | 0.0412344 | 0.0265082 | IL1R1/IL1A/IRAK2/IL1RAP/MAP3K8/NFKBIA/FOS/MBP | 8 |
| ZAMORA_NOS2_TARGETS_DN | ZAMORA_NOS2_TARGETS_DN | ZAMORA_NOS2_TARGETS_DN | 11/1438 | 81/23056 | 0.1358025 | 2.177373 | 2.737681 | 0.0116402 | 0.0413873 | 0.0266065 | CFH/CD36/FZD4/SLC6A13/VWF/ALOX5AP/ZFP36L1/JUP/SCN1B/RRAS/MYH9 | 11 |
| GOBP_INTERLEUKIN_8_PRODUCTION | GOBP_INTERLEUKIN_8_PRODUCTION | GOBP_INTERLEUKIN_8_PRODUCTION | 13/1438 | 103/23056 | 0.1262136 | 2.023630 | 2.685322 | 0.0116947 | 0.0414539 | 0.0266493 | PTPN22/PTPRC/IL1B/WNT5A/TLR3/F2RL1/IL6/SERPINE1/DDX58/ANXA1/KLF4/ELANE/BCL3 | 13 |
| GOBP_PEPTIDYL_TYROSINE_DEPHOSPHORYLATION | GOBP_PEPTIDYL_TYROSINE_DEPHOSPHORYLATION | GOBP_PEPTIDYL_TYROSINE_DEPHOSPHORYLATION | 13/1438 | 103/23056 | 0.1262136 | 2.023630 | 2.685322 | 0.0116947 | 0.0414539 | 0.0266493 | PTPN22/PTPRC/PTPN7/PTPN14/PTP4A1/PTPRK/PTPRZ1/PTPN3/DUSP13/PTPRE/PTPRJ/UBASH3B/TNS2 | 13 |
| GOBP_TRIGLYCERIDE_METABOLIC_PROCESS | GOBP_TRIGLYCERIDE_METABOLIC_PROCESS | GOBP_TRIGLYCERIDE_METABOLIC_PROCESS | 13/1438 | 103/23056 | 0.1262136 | 2.023630 | 2.685322 | 0.0116947 | 0.0414539 | 0.0266493 | CPS1/MGLL/AADAC/GPAT3/CAV1/PLAAT3/APOC3/APOA1/CETP/LIPG/C3/APOE/PNPLA3 | 13 |
| WP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER | WP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER | WP_LNCRNA_IN_CANONICAL_WNT_SIGNALING_AND_COLORECTAL_CANCER | 13/1438 | 103/23056 | 0.1262136 | 2.023630 | 2.685322 | 0.0116947 | 0.0414539 | 0.0266493 | WNT5A/LEF1/NKD2/TFAP2A/FZD1/FZD6/FZD8/DKK1/PLAU/TCF7L2/FOSL1/WNT10B/WNT7B | 13 |
| WP_RAS_SIGNALING | WP_RAS_SIGNALING | WP_RAS_SIGNALING | 20/1438 | 185/23056 | 0.1081081 | 1.733338 | 2.582866 | 0.0117091 | 0.0414539 | 0.0266493 | EPHA2/PLA2G4A/RASSF5/RASGRP3/PLD1/FGFR3/KDR/MET/TEK/HTR7/FGFR2/PLAAT3/FLT3/FLT1/PLA2G4D/LAT/GNGT2/PLA2G4C/RRAS/RAC2 | 20 |
| GOBP_REGULATION_OF_CELL_PROJECTION_ASSEMBLY | GOBP_REGULATION_OF_CELL_PROJECTION_ASSEMBLY | GOBP_REGULATION_OF_CELL_PROJECTION_ASSEMBLY | 23/1438 | 222/23056 | 0.1036036 | 1.661116 | 2.552803 | 0.0117997 | 0.0414539 | 0.0266493 | AGRN/EPHA2/PLD1/SLIT2/ARHGAP24/ADAMTS16/MYO10/MCIDAS/F2RL1/CAV1/PODXL/NRP1/EPS8L2/YAP1/EPS8/PLEK2/CCR7/HAP1/ICAM1/CDC42EP5/RAC2/CDC42EP1/TENM1 | 23 |
| BIOCARTA_CLASSIC_PATHWAY | BIOCARTA_CLASSIC_PATHWAY | BIOCARTA_CLASSIC_PATHWAY | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | C9/C1S/C1R/C3 | 4 |
| BIOCARTA_IL17_PATHWAY | BIOCARTA_IL17_PATHWAY | BIOCARTA_IL17_PATHWAY | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CD34/CXCL8/IL6/CSF3 | 4 |
| CHANG_POU5F1_TARGETS_UP | CHANG_POU5F1_TARGETS_UP | CHANG_POU5F1_TARGETS_UP | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CCN1/COL3A1/FN1/COL5A1 | 4 |
| FIGUEROA_AML_METHYLATION_CLUSTER_4_DN | FIGUEROA_AML_METHYLATION_CLUSTER_4_DN | FIGUEROA_AML_METHYLATION_CLUSTER_4_DN | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | EPHA2/CSGALNACT1/CCR7/GNGT2 | 4 |
| GOBP_BUNDLE_OF_HIS_CELL_TO_PURKINJE_MYOCYTE_COMMUNICATION | GOBP_BUNDLE_OF_HIS_CELL_TO_PURKINJE_MYOCYTE_COMMUNICATION | GOBP_BUNDLE_OF_HIS_CELL_TO_PURKINJE_MYOCYTE_COMMUNICATION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | DSP/KCNA5/JUP/DSG2 | 4 |
| GOBP_CDC42_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_CDC42_PROTEIN_SIGNAL_TRANSDUCTION | GOBP_CDC42_PROTEIN_SIGNAL_TRANSDUCTION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | NRP1/APOC3/APOA1/APOE | 4 |
| GOBP_CELL_PROLIFERATION_IN_HINDBRAIN | GOBP_CELL_PROLIFERATION_IN_HINDBRAIN | GOBP_CELL_PROLIFERATION_IN_HINDBRAIN | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | EGF/SHH/GLI1/LHX1 | 4 |
| GOBP_CHONDROCYTE_DIFFERENTIATION_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS | GOBP_CHONDROCYTE_DIFFERENTIATION_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS | GOBP_CHONDROCYTE_DIFFERENTIATION_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | TGFBR2/COL27A1/SERPINH1/SOX9 | 4 |
| GOBP_COLLECTING_DUCT_DEVELOPMENT | GOBP_COLLECTING_DUCT_DEVELOPMENT | GOBP_COLLECTING_DUCT_DEVELOPMENT | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | SHH/NOTCH1/BMP4/WNT7B | 4 |
| GOBP_HEPARIN_METABOLIC_PROCESS | GOBP_HEPARIN_METABOLIC_PROCESS | GOBP_HEPARIN_METABOLIC_PROCESS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CSGALNACT1/ANGPT1/EXT1/EDNRB | 4 |
| GOBP_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_CLEARANCE | GOBP_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_CLEARANCE | GOBP_HIGH_DENSITY_LIPOPROTEIN_PARTICLE_CLEARANCE | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | APOC3/APOA1/LIPG/APOE | 4 |
| GOBP_NEGATIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CD274/PDCD1LG2/LRRC32/PRNP | 4 |
| GOBP_NEGATIVE_REGULATION_OF_CALCINEURIN_MEDIATED_SIGNALING | GOBP_NEGATIVE_REGULATION_OF_CALCINEURIN_MEDIATED_SIGNALING | GOBP_NEGATIVE_REGULATION_OF_CALCINEURIN_MEDIATED_SIGNALING | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | ATP2B4/MYOZ2/MYOZ1/PRNP | 4 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_ADHESION_MOLECULE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_CELL_ADHESION_MOLECULE_PRODUCTION | GOBP_NEGATIVE_REGULATION_OF_CELL_ADHESION_MOLECULE_PRODUCTION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CXCL8/NOTCH1/APOA1/MYOCD | 4 |
| GOBP_NEGATIVE_REGULATION_OF_KERATINOCYTE_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_KERATINOCYTE_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_KERATINOCYTE_PROLIFERATION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CD109/PTPRK/EPPK1/FGFR2 | 4 |
| GOBP_PHOSPHOLIPID_HOMEOSTASIS | GOBP_PHOSPHOLIPID_HOMEOSTASIS | GOBP_PHOSPHOLIPID_HOMEOSTASIS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | ITGB6/APOA1/CETP/LIPG | 4 |
| GOBP_POSITIVE_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | WNT5A/DAB2/RSPO3/DKK1 | 4 |
| GOBP_PRIMARY_ALCOHOL_CATABOLIC_PROCESS | GOBP_PRIMARY_ALCOHOL_CATABOLIC_PROCESS | GOBP_PRIMARY_ALCOHOL_CATABOLIC_PROCESS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | SULT1E1/AKR1B10/AKR1C3/ALDH3B1 | 4 |
| GOBP_SKELETAL_MUSCLE_CELL_PROLIFERATION | GOBP_SKELETAL_MUSCLE_CELL_PROLIFERATION | GOBP_SKELETAL_MUSCLE_CELL_PROLIFERATION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | SHH/ANGPT1/SIX1/SIX5 | 4 |
| GOMF_CARBONATE_DEHYDRATASE_ACTIVITY | GOMF_CARBONATE_DEHYDRATASE_ACTIVITY | GOMF_CARBONATE_DEHYDRATASE_ACTIVITY | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CA13/CA1/CA3/CA12 | 4 |
| GOMF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | GOMF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | GOMF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CASP10/CASP8/CASP4/CASP1 | 4 |
| GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_ACTIVITY | GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_ACTIVITY | GOMF_LOW_DENSITY_LIPOPROTEIN_PARTICLE_RECEPTOR_ACTIVITY | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | LRP1B/STAB1/CD36/LRP10 | 4 |
| GOMF_PHOSPHATIDYLGLYCEROL_BINDING | GOMF_PHOSPHATIDYLGLYCEROL_BINDING | GOMF_PHOSPHATIDYLGLYCEROL_BINDING | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | RPE65/MME/ANXA13/GSDMD | 4 |
| HOLLERN_MICROACINAR_BREAST_TUMOR_DN | HOLLERN_MICROACINAR_BREAST_TUMOR_DN | HOLLERN_MICROACINAR_BREAST_TUMOR_DN | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | ACKR3/DRAM1/TNFAIP2/ADAMTS5 | 4 |
| HP_ABNORMAL_FINGER_FLEXION_CREASES | HP_ABNORMAL_FINGER_FLEXION_CREASES | HP_ABNORMAL_FINGER_FLEXION_CREASES | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | TBX15/TPM2/NOG/PIEZO2 | 4 |
| HP_ABNORMAL_PLACENTAL_SIZE | HP_ABNORMAL_PLACENTAL_SIZE | HP_ABNORMAL_PLACENTAL_SIZE | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | HSPG2/PLAG1/HMGA2/IGF1 | 4 |
| HP_ABNORMALITY_OF_METACARPAL_EPIPHYSES | HP_ABNORMALITY_OF_METACARPAL_EPIPHYSES | HP_ABNORMALITY_OF_METACARPAL_EPIPHYSES | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | FGFRL1/SALL1/COL9A3/BGN | 4 |
| HP_ABNORMALITY_OF_THE_5TH_METACARPAL | HP_ABNORMALITY_OF_THE_5TH_METACARPAL | HP_ABNORMALITY_OF_THE_5TH_METACARPAL | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | RUNX2/FBN1/NOG/BMP2 | 4 |
| HP_CARDIAC_SHUNT | HP_CARDIAC_SHUNT | HP_CARDIAC_SHUNT | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | CITED2/ACTC1/FOXF1/GATA6 | 4 |
| HP_DECREASED_SIZE_OF_NERVE_TERMINALS | HP_DECREASED_SIZE_OF_NERVE_TERMINALS | HP_DECREASED_SIZE_OF_NERVE_TERMINALS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | AGRN/LAMB2/DOK7/COL13A1 | 4 |
| HP_DIAPHRAGMATIC_WEAKNESS | HP_DIAPHRAGMATIC_WEAKNESS | HP_DIAPHRAGMATIC_WEAKNESS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | COL6A3/COL12A1/BAG3/COL6A2 | 4 |
| HP_HIP_FLEXOR_WEAKNESS | HP_HIP_FLEXOR_WEAKNESS | HP_HIP_FLEXOR_WEAKNESS | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | AGRN/DOK7/FLNC/COL13A1 | 4 |
| HP_MIDLINE_DEFECT_OF_THE_NOSE | HP_MIDLINE_DEFECT_OF_THE_NOSE | HP_MIDLINE_DEFECT_OF_THE_NOSE | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | NUAK2/ALX4/GRIP1/FREM2 | 4 |
| HP_PROPORTIONATE_TALL_STATURE | HP_PROPORTIONATE_TALL_STATURE | HP_PROPORTIONATE_TALL_STATURE | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | PPARG/CAV1/FOS/CAVIN1 | 4 |
| MATZUK_OVULATION | MATZUK_OVULATION | MATZUK_OVULATION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | PTGS2/SULT1E1/PGR/CEBPB | 4 |
| REACTOME_ERBB2_REGULATES_CELL_MOTILITY | REACTOME_ERBB2_REGULATES_CELL_MOTILITY | REACTOME_ERBB2_REGULATES_CELL_MOTILITY | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | EREG/BTC/EGF/HBEGF | 4 |
| REACTOME_HEME_DEGRADATION | REACTOME_HEME_DEGRADATION | REACTOME_HEME_DEGRADATION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | ABCG2/SLCO2B1/BLVRB/HMOX1 | 4 |
| REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | ITGA10/ITGA2/VWF/COL1A1 | 4 |
| REACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX | REACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX | REACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | PTGS2/PTGS1/AKR1C3/PTGIS | 4 |
| REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | WWTR1/RUNX2/CCN2/YAP1 | 4 |
| SCHAVOLT_TARGETS_OF_TP53_AND_TP63 | SCHAVOLT_TARGETS_OF_TP53_AND_TP63 | SCHAVOLT_TARGETS_OF_TP53_AND_TP63 | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | EPHA2/PODXL/FAS/CASP1 | 4 |
| WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE | WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE | WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | ADCY10/ADRB2/ADCY8/ADRA1D | 4 |
| WP_SOMATIC_SEX_DETERMINATION | WP_SOMATIC_SEX_DETERMINATION | WP_SOMATIC_SEX_DETERMINATION | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | FOXL2/WT1/SOX8/SOX9 | 4 |
| ZHENG_RESPONSE_TO_ARSENITE_UP | ZHENG_RESPONSE_TO_ARSENITE_UP | ZHENG_RESPONSE_TO_ARSENITE_UP | 4/1438 | 15/23056 | 0.2666667 | 4.275568 | 3.272923 | 0.0118099 | 0.0414539 | 0.0266493 | FOSL1/MT2A/MT1X/HMOX1 | 4 |
| GOMF_HISTONE_DEACETYLASE_BINDING | GOMF_HISTONE_DEACETYLASE_BINDING | GOMF_HISTONE_DEACETYLASE_BINDING | 15/1438 | 126/23056 | 0.1190476 | 1.908736 | 2.638002 | 0.0119284 | 0.0418486 | 0.0269030 | HES1/LEF1/GCM1/GLI3/NACC2/ANKRD1/BHLHE41/DACT1/MYOCD/BCL3/CEBPB/MAGEA9B/MAGEA9/MAGEA10/MAGEA1 | 15 |
| HP_APLASIA_HYPOPLASIA_INVOLVING_THE_METACARPAL_BONES | HP_APLASIA_HYPOPLASIA_INVOLVING_THE_METACARPAL_BONES | HP_APLASIA_HYPOPLASIA_INVOLVING_THE_METACARPAL_BONES | 15/1438 | 126/23056 | 0.1190476 | 1.908736 | 2.638002 | 0.0119284 | 0.0418486 | 0.0269030 | PTCH2/TWIST2/CD96/FAT4/RUNX2/GLI3/SHH/TRPS1/EXT1/FBN1/NOG/KCNJ2/BMP2/COL9A3/BGN | 15 |
| HP_ABNORMAL_TONGUE_MORPHOLOGY | HP_ABNORMAL_TONGUE_MORPHOLOGY | HP_ABNORMAL_TONGUE_MORPHOLOGY | 30/1438 | 311/23056 | 0.0964630 | 1.546628 | 2.503131 | 0.0119612 | 0.0419528 | 0.0269700 | FUCA1/PTPN22/TBX15/ECM1/KCNN3/PRRX1/PPARG/COL7A1/WNT5A/SH3TC2/EDN1/PSMB8/RUNX2/LAMA2/FAM20C/GLI3/TMEM270/SLC26A4/CAV1/RSPO2/GSN/MMP1/GRIP1/FREM2/BMP4/FOS/CAVIN1/SOX9/SRPX2/GPC4 | 30 |
| GOCC_CELL_LEADING_EDGE | GOCC_CELL_LEADING_EDGE | GOCC_CELL_LEADING_EDGE | 38/1438 | 416/23056 | 0.0913462 | 1.464588 | 2.466211 | 0.0120816 | 0.0423642 | 0.0272345 | EPHA2/S100A11/ACTG2/CAPG/DPP4/FAP/PHLDB2/MYLK/MYO10/IQGAP2/ABLIM3/PTPRK/ARHGAP18/PODXL/DDX58/GSN/AIF1L/ITGA8/APBB1IP/JCAD/EPS8L2/CD44/PTPRJ/LAYN/EPS8/ITGA5/LCP1/AJUBA/PLEK2/ACTC1/TPM1/CSPG4/PIEZO1/ITGB4/MYH9/RAC2/ARHGEF6/GABRE | 38 |
| HP_INFERTILITY | HP_INFERTILITY | HP_INFERTILITY | 21/1438 | 198/23056 | 0.1060606 | 1.700510 | 2.553184 | 0.0122274 | 0.0427060 | 0.0274542 | HJV/FCGR2A/CFAP221/CCDC141/CATIP/FOXL2/DNAH5/MCIDAS/CCNO/HFE/SIM1/ZFPM2/CFAP58/WT1/CATSPER1/PGR/BTG4/CYP19A1/SOX9/AXL/TGFB1 | 21 |
| COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | 16/1438 | 138/23056 | 0.1159420 | 1.858943 | 2.610175 | 0.0122358 | 0.0427060 | 0.0274542 | ERRFI1/CDA/PRG4/RASSF5/CCDC85A/SULT1E1/GSDMD/BAG3/EPS8L2/HMGA2/NFKBIA/OSGIN1/ABCC3/GADD45B/RELB/COL18A1 | 16 |
| GOCC_PHAGOCYTIC_VESICLE | GOCC_PHAGOCYTIC_VESICLE | GOCC_PHAGOCYTIC_VESICLE | 16/1438 | 138/23056 | 0.1159420 | 1.858943 | 2.610175 | 0.0122358 | 0.0427060 | 0.0274542 | CTSS/RAB7B/ITGB5/ANXA3/HLA-E/HLA-C/TAPBP/CD36/ATP6V0A4/ZYX/GSN/RAB38/RAB20/FMNL1/ELANE/RAC2 | 16 |
| WP_MEASLES_VIRUS_INFECTION | WP_MEASLES_VIRUS_INFECTION | WP_MEASLES_VIRUS_INFECTION | 16/1438 | 138/23056 | 0.1159420 | 1.858943 | 2.610175 | 0.0122358 | 0.0427060 | 0.0274542 | IKBKE/IL1A/IL1B/CASP8/TNFAIP3/IL6/DDX58/FAS/NFKB2/IRF9/NFKBIA/FOS/CLEC4M/MX1/IL2RB/MSN | 16 |
| GOBP_BRANCHING_INVOLVED_IN_MAMMARY_GLAND_DUCT_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_MAMMARY_GLAND_DUCT_MORPHOGENESIS | GOBP_BRANCHING_INVOLVED_IN_MAMMARY_GLAND_DUCT_MORPHOGENESIS | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | EPHA2/CSF1/WNT5A/DDR1/PGR | 5 |
| GOBP_CALCIUM_INDEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | GOBP_CALCIUM_INDEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | GOBP_CALCIUM_INDEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | CLDN1/CLDN16/CLDN6/CLDN7/BMP2 | 5 |
| GOBP_CELLULAR_RESPONSE_TO_DSRNA | GOBP_CELLULAR_RESPONSE_TO_DSRNA | GOBP_CELLULAR_RESPONSE_TO_DSRNA | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | TLR3/STING1/CAV1/DDX58/COLEC12 | 5 |
| GOBP_LUNG_CELL_DIFFERENTIATION | GOBP_LUNG_CELL_DIFFERENTIATION | GOBP_LUNG_CELL_DIFFERENTIATION | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | THRB/YAP1/SOX9/GATA6/KLF2 | 5 |
| GOBP_LYMPH_VESSEL_MORPHOGENESIS | GOBP_LYMPH_VESSEL_MORPHOGENESIS | GOBP_LYMPH_VESSEL_MORPHOGENESIS | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | EPHA2/TIE1/PTPN14/VEGFC/FOXC1 | 5 |
| GOBP_PHASIC_SMOOTH_MUSCLE_CONTRACTION | GOBP_PHASIC_SMOOTH_MUSCLE_CONTRACTION | GOBP_PHASIC_SMOOTH_MUSCLE_CONTRACTION | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | HTR1D/EDN2/GDNF/EDN1/EDNRB | 5 |
| GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | PTPN22/PTPRC/TGFBR2/HLA-E/EBI3 | 5 |
| GOBP_REGULATION_OF_PRODUCTION_OF_SMALL_RNA_INVOLVED_IN_GENE_SILENCING_BY_RNA | GOBP_REGULATION_OF_PRODUCTION_OF_SMALL_RNA_INVOLVED_IN_GENE_SILENCING_BY_RNA | GOBP_REGULATION_OF_PRODUCTION_OF_SMALL_RNA_INVOLVED_IN_GENE_SILENCING_BY_RNA | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | ZC3H12A/IL6/BMP4/MYOCD/TGFB1 | 5 |
| GOBP_REGULATION_OF_RECEPTOR_BINDING | GOBP_REGULATION_OF_RECEPTOR_BINDING | GOBP_REGULATION_OF_RECEPTOR_BINDING | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | HFE/NRP1/PHLDA2/ANXA2/NOG | 5 |
| GOCC_ENDOCYTIC_VESICLE_LUMEN | GOCC_ENDOCYTIC_VESICLE_LUMEN | GOCC_ENDOCYTIC_VESICLE_LUMEN | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | SPARC/SAA1/APOA1/CSF3/APOE | 5 |
| GOCC_M_BAND | GOCC_M_BAND | GOCC_M_BAND | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | TRIM63/LMOD2/CRYAB/MYOM1/SMPX | 5 |
| GOMF_FIBROBLAST_GROWTH_FACTOR_BINDING | GOMF_FIBROBLAST_GROWTH_FACTOR_BINDING | GOMF_FIBROBLAST_GROWTH_FACTOR_BINDING | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | S100A13/FGFRL1/FGFR3/FGFR2/THBS1 | 5 |
| HINATA_NFKB_TARGETS_KERATINOCYTE_DN | HINATA_NFKB_TARGETS_KERATINOCYTE_DN | HINATA_NFKB_TARGETS_KERATINOCYTE_DN | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | GPRC5A/THBS1/KLK6/RUNX1/ZNF185 | 5 |
| HP_ABDOMINAL_AORTIC_ANEURYSM | HP_ABDOMINAL_AORTIC_ANEURYSM | HP_ABDOMINAL_AORTIC_ANEURYSM | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | PTPN22/TGFB2/TGFBR2/MYLK/FBN1 | 5 |
| HP_ABNORMAL_5TH_FINGER_PHALANX_MORPHOLOGY | HP_ABNORMAL_5TH_FINGER_PHALANX_MORPHOLOGY | HP_ABNORMAL_5TH_FINGER_PHALANX_MORPHOLOGY | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | WNT5A/RUNX2/GJA1/NOG/BMP2 | 5 |
| HP_BRANCHIAL_ANOMALY | HP_BRANCHIAL_ANOMALY | HP_BRANCHIAL_ANOMALY | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | TFAP2A/SHH/ZIC2/SIX1/SIX5 | 5 |
| HP_DYSTROPHIC_TOENAIL | HP_DYSTROPHIC_TOENAIL | HP_DYSTROPHIC_TOENAIL | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | COL7A1/RUNX2/PERP/NOTCH1/ITGB4 | 5 |
| KEGG_NITROGEN_METABOLISM | KEGG_NITROGEN_METABOLISM | KEGG_NITROGEN_METABOLISM | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | CPS1/CA13/CA1/CA3/CA12 | 5 |
| MARKS_HDAC_TARGETS_UP | MARKS_HDAC_TARGETS_UP | MARKS_HDAC_TARGETS_UP | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | CASP8/RARB/GSN/FAS/GADD45B | 5 |
| ONO_FOXP3_TARGETS_UP | ONO_FOXP3_TARGETS_UP | ONO_FOXP3_TARGETS_UP | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | TNFRSF18/PDCD1LG2/FOS/CCR7/GADD45B | 5 |
| PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | GYPC/PPARG/IER3/ST3GAL1/ALOX5AP | 5 |
| WILLERT_WNT_SIGNALING | WILLERT_WNT_SIGNALING | WILLERT_WNT_SIGNALING | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | GYPC/GJA1/CITED2/TNFRSF11B/EDNRB | 5 |
| WP_BLOOD_CLOTTING_CASCADE | WP_BLOOD_CLOTTING_CASCADE | WP_BLOOD_CLOTTING_CASCADE | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | SERPINE1/PLAT/PLAU/VWF/SERPINB2 | 5 |
| WP_KYNURENINE_PATHWAY_AND_LINKS_TO_CELL_SENESCENCE | WP_KYNURENINE_PATHWAY_AND_LINKS_TO_CELL_SENESCENCE | WP_KYNURENINE_PATHWAY_AND_LINKS_TO_CELL_SENESCENCE | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | KYNU/TDO2/AHR/IDO1/FOXO1 | 5 |
| WP_NRF2ARE_REGULATION | WP_NRF2ARE_REGULATION | WP_NRF2ARE_REGULATION | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | SLC7A11/NQO1/MAF/CEBPB/HMOX1 | 5 |
| WU_HBX_TARGETS_2_UP | WU_HBX_TARGETS_2_UP | WU_HBX_TARGETS_2_UP | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | TGFB2/CXCL1/FAS/CASP4/ANPEP | 5 |
| ZIRN_TRETINOIN_RESPONSE_WT1_UP | ZIRN_TRETINOIN_RESPONSE_WT1_UP | ZIRN_TRETINOIN_RESPONSE_WT1_UP | 5/1438 | 23/23056 | 0.2173913 | 3.485517 | 3.075811 | 0.0122755 | 0.0427060 | 0.0274542 | DHRS3/RARB/LRRC32/IGFBP6/COTL1 | 5 |
| BAE_BRCA1_TARGETS_UP | BAE_BRCA1_TARGETS_UP | BAE_BRCA1_TARGETS_UP | 10/1438 | 71/23056 | 0.1408451 | 2.258223 | 2.738537 | 0.0123492 | 0.0429190 | 0.0275912 | MTMR11/TGFB2/KYNU/ANXA1/ALOX5/STAT6/KRT19/JUP/SAT1/COL4A5 | 10 |
| BOYLAN_MULTIPLE_MYELOMA_PCA3_DN | BOYLAN_MULTIPLE_MYELOMA_PCA3_DN | BOYLAN_MULTIPLE_MYELOMA_PCA3_DN | 10/1438 | 71/23056 | 0.1408451 | 2.258223 | 2.738537 | 0.0123492 | 0.0429190 | 0.0275912 | IL7R/ADAM19/CRYBG1/GSDMD/PTGR1/GSN/CASP1/MYL9/CYTH4/CYSLTR1 | 10 |
| GOBP_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | GOBP_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS | 10/1438 | 71/23056 | 0.1408451 | 2.258223 | 2.738537 | 0.0123492 | 0.0429190 | 0.0275912 | ZC3H12A/AGT/TGFBR2/F2RL1/SOD2/CD36/AKR1C3/THBS1/TGFB1/PDGFB | 10 |
| KEGG_MELANOMA | KEGG_MELANOMA | KEGG_MELANOMA | 10/1438 | 71/23056 | 0.1408451 | 2.258223 | 2.738537 | 0.0123492 | 0.0429190 | 0.0275912 | MITF/FGF5/EGF/PDGFC/FGF18/PDGFA/MET/FGF20/IGF1/PDGFB | 10 |
| ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | 20/1438 | 186/23056 | 0.1075269 | 1.724019 | 2.556983 | 0.0123757 | 0.0430003 | 0.0276434 | FUCA1/ECM1/TMEM158/MICA/MICB/SYNJ2/FLNC/PARP12/CLIC3/CYP26A1/DNMBP/NRIP3/EHD4/MMP2/CAVIN1/KDELR3/SSX1/SSX2/SPANXA1/MAGEA9 | 20 |
| HP_ABNORMALITY_OF_THE_GINGIVA | HP_ABNORMALITY_OF_THE_GINGIVA | HP_ABNORMALITY_OF_THE_GINGIVA | 23/1438 | 223/23056 | 0.1031390 | 1.653667 | 2.529774 | 0.0124056 | 0.0430932 | 0.0277032 | GFI1/ECM1/KCNN3/COL3A1/NABP1/WNT5A/CD96/ADAMTS3/FAT4/ADAMTS2/DSP/PERP/FAM20C/TMEM270/SAMD9/FGFR2/C1S/C1R/MMP14/IRF9/MMP2/ELANE/RIN2 | 23 |
| GOBP_CELL_CELL_JUNCTION_ASSEMBLY | GOBP_CELL_CELL_JUNCTION_ASSEMBLY | GOBP_CELL_CELL_JUNCTION_ASSEMBLY | 17/1438 | 150/23056 | 0.1133333 | 1.817116 | 2.589460 | 0.0124134 | 0.0430984 | 0.0277065 | EPHA2/RHOC/AGT/IL1B/HEG1/CLDN1/CLDN16/CDH9/GJA1/MICALL2/CAV1/ZNF703/VCL/CLDN6/CLDN7/JUP/PECAM1 | 17 |
| WP_REGULATION_OF_ACTIN_CYTOSKELETON | WP_REGULATION_OF_ACTIN_CYTOSKELETON | WP_REGULATION_OF_ACTIN_CYTOSKELETON | 17/1438 | 150/23056 | 0.1133333 | 1.817116 | 2.589460 | 0.0124134 | 0.0430984 | 0.0277065 | FN1/MYLK/FGFR3/FGF5/EGF/FGF18/PDGFA/FGF20/GSN/VCL/FGFR2/BDKRB1/RRAS/RAC2/PDGFB/MSN/ARHGEF6 | 17 |
| HP_GLAUCOMA | HP_GLAUCOMA | HP_GLAUCOMA | 33/1438 | 351/23056 | 0.0940171 | 1.507412 | 2.470629 | 0.0124777 | 0.0433109 | 0.0278431 | PTCH2/RPE65/PTPN22/NLRP3/COL3A1/FGFR3/SLC4A4/ADAMTS3/FAT4/FOXC1/RREB1/TENT5A/GJA1/AHR/TMEM270/GLIS3/TEK/DDX58/GSN/FAS/FGFR2/WT1/YAP1/FREM2/LTBP2/FBN1/LOXL1/MAF/MAG/TGFB1/COL18A1/IL2RB/NDP | 33 |
| GOBP_FATTY_ACID_BIOSYNTHETIC_PROCESS | GOBP_FATTY_ACID_BIOSYNTHETIC_PROCESS | GOBP_FATTY_ACID_BIOSYNTHETIC_PROCESS | 18/1438 | 162/23056 | 0.1111111 | 1.781487 | 2.574379 | 0.0124836 | 0.0433204 | 0.0278492 | EDN2/PTGS2/PLA2G4A/IL1B/MGLL/TECRL/EDN1/PDK4/ANXA1/PTGS1/AKR1C3/ALOX5/APOC3/APOA1/ACSM3/GIP/LIPG/PTGIS | 18 |
| BILBAN_B_CLL_LPL_DN | BILBAN_B_CLL_LPL_DN | BILBAN_B_CLL_LPL_DN | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | IER3/ANXA1/KLF4/FOS/PRNP/SAT1/ARHGEF6 | 7 |
| GOBP_NEGATIVE_REGULATION_OF_GLIOGENESIS | GOBP_NEGATIVE_REGULATION_OF_GLIOGENESIS | GOBP_NEGATIVE_REGULATION_OF_GLIOGENESIS | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | DLX1/DLX2/HES1/ID4/NOTCH1/PITX3/NOG | 7 |
| GOBP_NEUTRAL_LIPID_CATABOLIC_PROCESS | GOBP_NEUTRAL_LIPID_CATABOLIC_PROCESS | GOBP_NEUTRAL_LIPID_CATABOLIC_PROCESS | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | CPS1/MGLL/AADAC/APOC3/APOA1/LIPG/PNPLA3 | 7 |
| GOBP_RESPONSE_TO_COPPER_ION | GOBP_RESPONSE_TO_COPPER_ION | GOBP_RESPONSE_TO_COPPER_ION | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | IL1A/SOD3/AQP1/LOXL2/MT2A/MT1X/PRNP | 7 |
| GOBP_RESPONSE_TO_TESTOSTERONE | GOBP_RESPONSE_TO_TESTOSTERONE | GOBP_RESPONSE_TO_TESTOSTERONE | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | SRD5A2/SPP1/EDN1/THBS1/NQO1/HOXB13/MSN | 7 |
| GOBP_STEROID_HORMONE_BIOSYNTHETIC_PROCESS | GOBP_STEROID_HORMONE_BIOSYNTHETIC_PROCESS | GOBP_STEROID_HORMONE_BIOSYNTHETIC_PROCESS | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | SRD5A2/DAB2/BMP6/AKR1B15/ADM/CYP19A1/BMP2 | 7 |
| HP_ABNORMALITY_OF_THE_UMBILICAL_CORD | HP_ABNORMALITY_OF_THE_UMBILICAL_CORD | HP_ABNORMALITY_OF_THE_UMBILICAL_CORD | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | HSPG2/ADGRG6/SERPINE1/WT1/FOXF1/GATA6/RAC2 | 7 |
| HP_MEGALENCEPHALY | HP_MEGALENCEPHALY | HP_MEGALENCEPHALY | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | FGFR3/SHH/GAS1/FGFR2/HEPACAM/ZIC2/MLC1 | 7 |
| HP_WEAK_CRY | HP_WEAK_CRY | HP_WEAK_CRY | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | AGRN/LAMB2/SIM1/LAMA2/TPM2/COL13A1/CRYAB | 7 |
| KEGG_GRAFT_VERSUS_HOST_DISEASE | KEGG_GRAFT_VERSUS_HOST_DISEASE | KEGG_GRAFT_VERSUS_HOST_DISEASE | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | IL1A/IL1B/HLA-E/HLA-C/IL6/FAS/KLRD1 | 7 |
| STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | RAI14/CAP2/MICB/ASPH/PAPSS2/MYOF/PRSS23 | 7 |
| VALK_AML_WITH_FLT3_ITD | VALK_AML_WITH_FLT3_ITD | VALK_AML_WITH_FLT3_ITD | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | LCT/IL1RAP/MMP2/HOXB2/HOXB3/PIEZO2/COL4A5 | 7 |
| WP_BLADDER_CANCER | WP_BLADDER_CANCER | WP_BLADDER_CANCER | 7/1438 | 41/23056 | 0.1707317 | 2.737406 | 2.871720 | 0.0125782 | 0.0435056 | 0.0279683 | FGFR3/CXCL8/EGF/HBEGF/MMP1/THBS1/MMP2 | 7 |
| HP_ABNORMALITY_OF_THE_ANTERIOR_FONTANELLE | HP_ABNORMALITY_OF_THE_ANTERIOR_FONTANELLE | HP_ABNORMALITY_OF_THE_ANTERIOR_FONTANELLE | 13/1438 | 104/23056 | 0.1250000 | 2.004173 | 2.647092 | 0.0126258 | 0.0436593 | 0.0280671 | NLRP3/WNT5A/FGFR3/FAT4/ADAMTS2/RUNX2/GLI3/GLIS3/FGFR2/MMP2/COL1A1/SOX9/PIEZO2 | 13 |
| HP_ABNORMALITY_OF_THE_CARPAL_BONES | HP_ABNORMALITY_OF_THE_CARPAL_BONES | HP_ABNORMALITY_OF_THE_CARPAL_BONES | 11/1438 | 82/23056 | 0.1341463 | 2.150819 | 2.692464 | 0.0127086 | 0.0439235 | 0.0282369 | FGFR3/SLC34A2/SHH/EXT1/FGFR2/GLI1/MMP14/MMP2/NOG/GPC4/BGN | 11 |
| ROSS_ACUTE_MYELOID_LEUKEMIA_CBF | ROSS_ACUTE_MYELOID_LEUKEMIA_CBF | ROSS_ACUTE_MYELOID_LEUKEMIA_CBF | 11/1438 | 82/23056 | 0.1341463 | 2.150819 | 2.692464 | 0.0127086 | 0.0439235 | 0.0282369 | ATP2B4/CD34/VAMP5/STK32B/SPARC/CAV1/TPK1/IL15RA/C11orf21/ITGB4/MN1 | 11 |
| GOBP_T_CELL_RECEPTOR_SIGNALING_PATHWAY | GOBP_T_CELL_RECEPTOR_SIGNALING_PATHWAY | GOBP_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 15/1438 | 127/23056 | 0.1181102 | 1.893706 | 2.604704 | 0.0127708 | 0.0441134 | 0.0283590 | ZC3H12A/GBP1/PTPN22/PTPRC/TXK/TEC/MOG/TNFRSF21/PTPRJ/TESPA1/CCR7/KCNN4/NECTIN2/PRNP/ICOSLG | 15 |
| HP_NEOPLASM_OF_THE_LIVER | HP_NEOPLASM_OF_THE_LIVER | HP_NEOPLASM_OF_THE_LIVER | 15/1438 | 127/23056 | 0.1181102 | 1.893706 | 2.604704 | 0.0127708 | 0.0441134 | 0.0283590 | CASP10/CASP8/TGFBR2/HFE/MET/PDGFRL/TNFSF15/FAS/WT1/STAT6/PYGL/SERPINA1/IL12RB1/BMP2/GPC4 | 15 |
| MEBARKI_HCC_PROGENITOR_WNT_DN | MEBARKI_HCC_PROGENITOR_WNT_DN | MEBARKI_HCC_PROGENITOR_WNT_DN | 12/1438 | 93/23056 | 0.1290323 | 2.068823 | 2.663712 | 0.0127732 | 0.0441134 | 0.0283590 | GASK1A/DOK7/SLIT2/TDRD6/ITGA8/KRT4/DIO2/USP43/MBP/PLIN4/SLC6A16/LGALS2 | 12 |
| GOBP_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | GOBP_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 9/1438 | 61/23056 | 0.1475410 | 2.365581 | 2.754354 | 0.0128615 | 0.0443958 | 0.0285405 | RHOC/S100A10/CCN2/ARHGEF5/NRP1/SYNPO2L/APOA1/TPM1/SDC4 | 9 |
| WP_NOVEL_INTRACELLULAR_COMPONENTS_OF_RIGILIKE_RECEPTOR_RLR_PATHWAY | WP_NOVEL_INTRACELLULAR_COMPONENTS_OF_RIGILIKE_RECEPTOR_RLR_PATHWAY | WP_NOVEL_INTRACELLULAR_COMPONENTS_OF_RIGILIKE_RECEPTOR_RLR_PATHWAY | 9/1438 | 61/23056 | 0.1475410 | 2.365581 | 2.754354 | 0.0128615 | 0.0443958 | 0.0285405 | IKBKE/CASP10/CASP8/CXCL8/STING1/IFNE/DDX58/NFKBIA/DHX58 | 9 |
| MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | 21/1438 | 199/23056 | 0.1055276 | 1.691965 | 2.528454 | 0.0128930 | 0.0444936 | 0.0286034 | HSPG2/TIE1/CCN1/PRELP/PTPN14/NID1/ALDH1L1/SOD3/LAMA4/SOD2/PDK4/FABP4/CA13/ANXA8L1/PPP1R3C/NID2/CSPG4/CAVIN1/ACSF2/SLC7A10/EHD2 | 21 |
| GOBP_DETECTION_OF_MECHANICAL_STIMULUS | GOBP_DETECTION_OF_MECHANICAL_STIMULUS | GOBP_DETECTION_OF_MECHANICAL_STIMULUS | 8/1438 | 51/23056 | 0.1568627 | 2.515040 | 2.793523 | 0.0130200 | 0.0447661 | 0.0287786 | SERPINE2/ITGA2/PKD1L1/TRPA1/TMC1/PIEZO1/JUP/PIEZO2 | 8 |
| GOBP_POSITIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION | GOBP_POSITIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION | 8/1438 | 51/23056 | 0.1568627 | 2.515040 | 2.793523 | 0.0130200 | 0.0447661 | 0.0287786 | EGF/VEGFC/GLI3/SHH/NOTCH1/PITX3/GLI1/LHX1 | 8 |
| HP_PETECHIAE | HP_PETECHIAE | HP_PETECHIAE | 8/1438 | 51/23056 | 0.1568627 | 2.515040 | 2.793523 | 0.0130200 | 0.0447661 | 0.0287786 | NABP1/CASP10/ITGA2/CD109/STX11/SAMD9/APOE/USP18 | 8 |
| HP_ULNAR_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | HP_ULNAR_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | HP_ULNAR_DEVIATION_OF_THE_HAND_OR_OF_FINGERS_OF_THE_HAND | 8/1438 | 51/23056 | 0.1568627 | 2.515040 | 2.793523 | 0.0130200 | 0.0447661 | 0.0287786 | CD96/ADGRG6/TPM2/DACT1/SALL1/PIEZO2/BMP2/COL9A3 | 8 |
| NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | 8/1438 | 51/23056 | 0.1568627 | 2.515040 | 2.793523 | 0.0130200 | 0.0447661 | 0.0287786 | S100A2/TPM2/IGFBP6/NFKBIA/ANXA2/MMP2/CD70/LGALS1 | 8 |
| WP_PHOTODYNAMIC_THERAPYINDUCED_AP1_SURVIVAL_SIGNALING | WP_PHOTODYNAMIC_THERAPYINDUCED_AP1_SURVIVAL_SIGNALING | WP_PHOTODYNAMIC_THERAPYINDUCED_AP1_SURVIVAL_SIGNALING | 8/1438 | 51/23056 | 0.1568627 | 2.515040 | 2.793523 | 0.0130200 | 0.0447661 | 0.0287786 | HBEGF/IL6/FAS/TNFRSF1A/FOS/BMF/MMP2/BCL3 | 8 |
| CAVARD_LIVER_CANCER_MALIGNANT_VS_BENIGN | CAVARD_LIVER_CANCER_MALIGNANT_VS_BENIGN | CAVARD_LIVER_CANCER_MALIGNANT_VS_BENIGN | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | DPP4/SPP1/FST/HLA-C/PTGR1/CES1 | 6 |
| GOBP_ANIMAL_ORGAN_MATURATION | GOBP_ANIMAL_ORGAN_MATURATION | GOBP_ANIMAL_ORGAN_MATURATION | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | FGFR3/ADAMTS12/EXT1/IGF1/ALDH1A2/BMP2 | 6 |
| GOBP_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | GOBP_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | IL1B/WNT5A/PHLDB2/DKK1/MMP14/THBS1 | 6 |
| GOBP_POSITIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION_INVOLVED_IN_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION_INVOLVED_IN_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_SIGNALING_PATHWAY | GOBP_POSITIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION_INVOLVED_IN_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_SIGNALING_PATHWAY | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | S1PR1/F2RL1/EDN1/GPR20/C3AR1/LPAR4 | 6 |
| HALLMARK_NOTCH_SIGNALING | HALLMARK_NOTCH_SIGNALING | HALLMARK_NOTCH_SIGNALING | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | WNT5A/HES1/FZD1/NOTCH1/TCF7L2/MAML2 | 6 |
| HP_PERIPHERAL_ARTERIAL_STENOSIS | HP_PERIPHERAL_ARTERIAL_STENOSIS | HP_PERIPHERAL_ARTERIAL_STENOSIS | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | LDLRAP1/TGFB2/TGFBR2/MYLK/FBN1/APOE | 6 |
| HP_POLYURIA | HP_POLYURIA | HP_POLYURIA | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | PTPN22/CLDN16/ITPR3/IL6/PLVAP/CYP24A1 | 6 |
| PID_SYNDECAN_4_PATHWAY | PID_SYNDECAN_4_PATHWAY | PID_SYNDECAN_4_PATHWAY | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | TFPI/FN1/ITGA5/THBS1/CCL5/SDC4 | 6 |
| POS_HISTAMINE_RESPONSE_NETWORK | POS_HISTAMINE_RESPONSE_NETWORK | POS_HISTAMINE_RESPONSE_NETWORK | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | IL15/NNMT/FBLN5/LOXL1/TGFB1/CEBPB | 6 |
| WP_DEVELOPMENT_AND_HETEROGENEITY_OF_THE_ILC_FAMILY | WP_DEVELOPMENT_AND_HETEROGENEITY_OF_THE_ILC_FAMILY | WP_DEVELOPMENT_AND_HETEROGENEITY_OF_THE_ILC_FAMILY | 6/1438 | 32/23056 | 0.1875000 | 3.006259 | 2.929043 | 0.0130242 | 0.0447661 | 0.0287786 | GFI1/IL1B/IL15/TSLP/AHR/IL6 | 6 |
| VANTVEER_BREAST_CANCER_ESR1_DN | VANTVEER_BREAST_CANCER_ESR1_DN | VANTVEER_BREAST_CANCER_ESR1_DN | 23/1438 | 224/23056 | 0.1026786 | 1.646284 | 2.506860 | 0.0130362 | 0.0447964 | 0.0287980 | EPHA2/PDZK1IP1/GBP1/S100A10/NMI/TM4SF1/FNDC3B/MYO10/FOXC1/TNFRSF21/TNFAIP3/SOD2/IDO1/IL15RA/SRGN/ADM/KRT7/GLIPR1/BCL2A1/CCL5/KCNN4/MID1/MSN | 23 |
| KEGG_WNT_SIGNALING_PATHWAY | KEGG_WNT_SIGNALING_PATHWAY | KEGG_WNT_SIGNALING_PATHWAY | 17/1438 | 151/23056 | 0.1125828 | 1.805082 | 2.559870 | 0.0132018 | 0.0453539 | 0.0291565 | WNT9A/WNT5A/PRICKLE2/LEF1/NKD2/FZD1/FZD6/FZD8/DKK1/TCF7L2/FOSL1/FZD4/WNT10B/NFATC4/NFATC2/RAC2/WNT7B | 17 |
| HP_AMBIGUOUS_GENITALIA | HP_AMBIGUOUS_GENITALIA | HP_AMBIGUOUS_GENITALIA | 14/1438 | 116/23056 | 0.1206897 | 1.935063 | 2.603919 | 0.0132417 | 0.0454795 | 0.0292372 | TBX15/SRD5A2/TWIST2/GLI3/SHH/ZFPM2/GAS1/WT1/MYRF/GRIP1/FREM2/ZIC2/CYP19A1/SOX9 | 14 |
| GOBP_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | GOBP_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 24/1438 | 237/23056 | 0.1012658 | 1.623633 | 2.488912 | 0.0133397 | 0.0458048 | 0.0294464 | ERRFI1/PTPN22/PTPRC/LAX1/AGT/IL1B/PPARG/HEG1/WWTR1/ZFYVE28/TNFAIP3/CAV1/FABP4/HHEX/PTPRJ/UBASH3B/GPRC5A/LATS2/AJUBA/BMP4/MYOCD/GADD45B/APOE/BMP2 | 24 |
| GOBP_SUPEROXIDE_METABOLIC_PROCESS | GOBP_SUPEROXIDE_METABOLIC_PROCESS | GOBP_SUPEROXIDE_METABOLIC_PROCESS | 10/1438 | 72/23056 | 0.1388889 | 2.226858 | 2.689070 | 0.0135633 | 0.0465377 | 0.0299175 | AGT/SOD3/F2RL1/EDN1/SOD2/CD36/PON3/FBLN5/NQO1/TGFB1 | 10 |
| GOMF_MYOSIN_BINDING | GOMF_MYOSIN_BINDING | GOMF_MYOSIN_BINDING | 10/1438 | 72/23056 | 0.1388889 | 2.226858 | 2.689070 | 0.0135633 | 0.0465377 | 0.0299175 | MLPH/NKD2/GSN/ACTC1/MYH8/HAP1/MYL4/LLGL2/AXL/MYL9 | 10 |
| KEGG_LEISHMANIA_INFECTION | KEGG_LEISHMANIA_INFECTION | KEGG_LEISHMANIA_INFECTION | 10/1438 | 72/23056 | 0.1388889 | 2.226858 | 2.689070 | 0.0135633 | 0.0465377 | 0.0299175 | FCGR2A/PTGS2/TGFB2/IL1A/IL1B/ITGA4/NFKBIA/FOS/C3/TGFB1 | 10 |
| GOMF_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY | GOMF_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY | GOMF_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY | 13/1438 | 105/23056 | 0.1238095 | 1.985085 | 2.609287 | 0.0136131 | 0.0466969 | 0.0300198 | PTPN22/PTPRC/PTPN7/PTPN14/PTP4A1/PTPRK/PTPRZ1/PTPN3/DUSP13/PTPRE/PTPRJ/UBASH3B/TNS2 | 13 |
| REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | 15/1438 | 128/23056 | 0.1171875 | 1.878912 | 2.571706 | 0.0136588 | 0.0468420 | 0.0301131 | PLA2G4A/OSBPL10/MGLL/PLD1/GPAT3/CDS1/PLAAT4/PLAAT3/PLA2G4D/LPCAT2/PITPNM3/PLA2G4C/CRLS1/PNPLA3/DGAT2L6 | 15 |
| HP_ABNORMALITY_OF_THE_TONGUE | HP_ABNORMALITY_OF_THE_TONGUE | HP_ABNORMALITY_OF_THE_TONGUE | 35/1438 | 380/23056 | 0.0921053 | 1.476759 | 2.416915 | 0.0138292 | 0.0473952 | 0.0304687 | FUCA1/PTPN22/TBX15/ECM1/KCNN3/PRRX1/CASP10/PPARG/COL7A1/WNT5A/SH3TC2/EDN1/PSMB8/RUNX2/LAMA2/PERP/FAM20C/GLI3/TMEM270/SLC26A4/CAV1/RSPO2/GSN/FAS/MMP1/GRIP1/FREM2/BMP4/FOS/CAVIN1/SOX9/CACNA1A/PDGFB/SRPX2/GPC4 | 35 |
| GOBP_NATURAL_KILLER_CELL_ACTIVATION | GOBP_NATURAL_KILLER_CELL_ACTIVATION | GOBP_NATURAL_KILLER_CELL_ACTIVATION | 12/1438 | 94/23056 | 0.1276596 | 2.046814 | 2.622908 | 0.0138374 | 0.0473952 | 0.0304687 | PTPN22/PTPRC/CASP8/IL15/HLA-E/MICA/IFNE/IL15RA/KLRC4-KLRK1/IL21R/AXL/IL2RB | 12 |
| GOMF_DIOXYGENASE_ACTIVITY | GOMF_DIOXYGENASE_ACTIVITY | GOMF_DIOXYGENASE_ACTIVITY | 12/1438 | 94/23056 | 0.1276596 | 2.046814 | 2.622908 | 0.0138374 | 0.0473952 | 0.0304687 | RPE65/PTGS2/P3H2/TDO2/IDO1/ASPH/PTGS1/ALOX5/BBOX1/P4HA3/HPD/ALOX5AP | 12 |
| HP_FLAT_FACE | HP_FLAT_FACE | HP_FLAT_FACE | 12/1438 | 94/23056 | 0.1276596 | 2.046814 | 2.622908 | 0.0138374 | 0.0473952 | 0.0304687 | HSPG2/COL3A1/FN1/WNT5A/FGFR3/ADAMTS3/FAT4/FGFR2/MAF/SOX9/COL9A3/MN1 | 12 |
| RASHI_RESPONSE_TO_IONIZING_RADIATION_6 | RASHI_RESPONSE_TO_IONIZING_RADIATION_6 | RASHI_RESPONSE_TO_IONIZING_RADIATION_6 | 12/1438 | 94/23056 | 0.1276596 | 2.046814 | 2.622908 | 0.0138374 | 0.0473952 | 0.0304687 | HTR1D/GBP2/PTPRC/PSMB9/MSC/FAS/HHEX/SLC38A4/SELPLG/CCL5/FMNL1/EMP3 | 12 |
| BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | 11/1438 | 83/23056 | 0.1325301 | 2.124906 | 2.647894 | 0.0138499 | 0.0474024 | 0.0304734 | PLA2G4A/TFPI/BHLHE40/PLK2/SERPINB1/TRPS1/TRIM5/PRSS23/RAB20/MT1X/SLC47A1 | 11 |
| GOMF_PDZ_DOMAIN_BINDING | GOMF_PDZ_DOMAIN_BINDING | GOMF_PDZ_DOMAIN_BINDING | 11/1438 | 83/23056 | 0.1325301 | 2.124906 | 2.647894 | 0.0138499 | 0.0474024 | 0.0304734 | ARHGEF16/ATP2B4/CRIM1/GRID2/SYNJ2/FZD1/GPR37/PLEKHA2/FZD8/FZD4/LLGL2 | 11 |
| HP_DECREASED_FERTILITY_IN_FEMALES | HP_DECREASED_FERTILITY_IN_FEMALES | HP_DECREASED_FERTILITY_IN_FEMALES | 11/1438 | 83/23056 | 0.1325301 | 2.124906 | 2.647894 | 0.0138499 | 0.0474024 | 0.0304734 | CFAP221/FOXL2/DNAH5/MCIDAS/CCNO/ZFPM2/WT1/PGR/BTG4/CYP19A1/SOX9 | 11 |
| GOCC_COATED_VESICLE_MEMBRANE | GOCC_COATED_VESICLE_MEMBRANE | GOCC_COATED_VESICLE_MEMBRANE | 19/1438 | 176/23056 | 0.1079545 | 1.730876 | 2.510305 | 0.0139537 | 0.0477340 | 0.0306865 | LDLRAP1/CNIH3/TGFA/WNT5A/EPGN/EREG/BTC/EGF/IL7R/DAB2/HBEGF/ADRB2/HLA-E/HLA-C/ADCY8/FZD4/COPZ2/APOE/KDELR3 | 19 |
| GOCC_LEADING_EDGE_MEMBRANE | GOCC_LEADING_EDGE_MEMBRANE | GOCC_LEADING_EDGE_MEMBRANE | 19/1438 | 176/23056 | 0.1079545 | 1.730876 | 2.510305 | 0.0139537 | 0.0477340 | 0.0306865 | EPHA2/DPP4/FAP/PTPRK/DDX58/AIF1L/ITGA8/JCAD/EPS8L2/CD44/PTPRJ/EPS8/ITGA5/LCP1/PLEK2/TPM1/CSPG4/PIEZO1/GABRE | 19 |
| HP_CONGENITAL_CONTRACTURE | HP_CONGENITAL_CONTRACTURE | HP_CONGENITAL_CONTRACTURE | 17/1438 | 152/23056 | 0.1118421 | 1.793207 | 2.530503 | 0.0140289 | 0.0479794 | 0.0308443 | AGRN/HSPG2/PRG4/ITGA6/DOK7/COL12A1/ADGRG6/FAM20C/GLI3/TPM2/MYPN/COL13A1/MYH8/MYH2/ITGB4/PIEZO2/SRPX2 | 17 |
| HP_APLASIA_HYPOPLASIA_OF_TOE | HP_APLASIA_HYPOPLASIA_OF_TOE | HP_APLASIA_HYPOPLASIA_OF_TOE | 18/1438 | 164/23056 | 0.1097561 | 1.759761 | 2.518323 | 0.0140361 | 0.0479918 | 0.0308523 | KCNN3/FGFRL1/FGFR3/IL7R/ADAMTS2/GJA1/GLI3/NOTCH1/FGFR2/WNT10B/GRIP1/DACT1/SALL1/NOG/SOX9/BMP2/ARSL/GPC4 | 18 |
| GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_DN | 9/1438 | 62/23056 | 0.1451613 | 2.327426 | 2.699313 | 0.0142373 | 0.0486434 | 0.0312712 | TNFRSF1B/CASP8/HOXA2/HOXA3/VWA5A/BMP4/HOXB3/GATA6/SIX5 | 9 |
| HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP | HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP | HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_UP | 9/1438 | 62/23056 | 0.1451613 | 2.327426 | 2.699313 | 0.0142373 | 0.0486434 | 0.0312712 | PLD1/PSMB9/TNFAIP3/ANXA1/LUM/MMP14/CDH13/CLDN7/GABRE | 9 |
| PID_IL12_2PATHWAY | PID_IL12_2PATHWAY | PID_IL12_2PATHWAY | 9/1438 | 62/23056 | 0.1451613 | 2.327426 | 2.699313 | 0.0142373 | 0.0486434 | 0.0312712 | IL1R1/IL1B/NFKB2/STAT6/FOS/GADD45B/IL12RB1/RELB/IL2RB | 9 |
| BARRIER_COLON_CANCER_RECURRENCE_UP | BARRIER_COLON_CANCER_RECURRENCE_UP | BARRIER_COLON_CANCER_RECURRENCE_UP | 7/1438 | 42/23056 | 0.1666667 | 2.672230 | 2.797556 | 0.0143029 | 0.0488069 | 0.0313763 | CFH/SULT1C2/TENT5A/FOXO1/ANXA2/KDELR3/ITM2A | 7 |
| GOBP_NEGATIVE_REGULATION_OF_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_PROLIFERATION | GOBP_NEGATIVE_REGULATION_OF_VASCULAR_ASSOCIATED_SMOOTH_MUSCLE_CELL_PROLIFERATION | 7/1438 | 42/23056 | 0.1666667 | 2.672230 | 2.797556 | 0.0143029 | 0.0488069 | 0.0313763 | PPARG/SOD2/EFEMP2/TPM1/MYOCD/CNN1/HMOX1 | 7 |
| HP_CELLULITIS | HP_CELLULITIS | HP_CELLULITIS | 7/1438 | 42/23056 | 0.1666667 | 2.672230 | 2.797556 | 0.0143029 | 0.0488069 | 0.0313763 | GFI1/VEGFC/TNFRSF1A/PIEZO1/COL1A1/ELANE/RAC2 | 7 |
| KEGG_BLADDER_CANCER | KEGG_BLADDER_CANCER | KEGG_BLADDER_CANCER | 7/1438 | 42/23056 | 0.1666667 | 2.672230 | 2.797556 | 0.0143029 | 0.0488069 | 0.0313763 | FGFR3/CXCL8/EGF/VEGFC/MMP1/THBS1/MMP2 | 7 |
| PID_BMP_PATHWAY | PID_BMP_PATHWAY | PID_BMP_PATHWAY | 7/1438 | 42/23056 | 0.1666667 | 2.672230 | 2.797556 | 0.0143029 | 0.0488069 | 0.0313763 | HJV/FST/BMP6/BMP4/SMAD6/NOG/BMP2 | 7 |
| HP_TOE_SYNDACTYLY | HP_TOE_SYNDACTYLY | HP_TOE_SYNDACTYLY | 23/1438 | 226/23056 | 0.1017699 | 1.631716 | 2.461371 | 0.0143742 | 0.0490379 | 0.0315248 | TBX15/TWIST2/CD96/FGFR3/GJA1/GLI3/SHH/CSGALNACT1/FGFR2/WNT10B/GRIP1/FREM2/BMP4/DACT1/SALL1/MYH8/NOG/KCNJ2/ITGB4/BMP2/FRMPD4/GPC4/ARHGEF6 | 23 |
| BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP | BREDEMEYER_RAG_SIGNALING_VIA_ATM_NOT_VIA_NFKB_UP | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | CRIM1/CSGALNACT1/TMEM71/MAP3K8/PRRG4/COLEC12/KCNK6/THBD | 8 |
| GOBP_APOPTOTIC_CELL_CLEARANCE | GOBP_APOPTOTIC_CELL_CLEARANCE | GOBP_APOPTOTIC_CELL_CLEARANCE | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | CD36/ANXA1/THBS1/MFGE8/C3/AXL/TGM2/RAC2 | 8 |
| GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | GOBP_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | DPP4/SLIT2/ADTRP/HOXA7/KLRC4-KLRK1/CYP19A1/IL27RA/HMOX1 | 8 |
| GOBP_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | GOBP_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | TNFRSF4/PTPRC/MZB1/HLA-E/IL6/STAT6/IL4R/TGFB1 | 8 |
| GOMF_NUCLEAR_RECEPTOR_ACTIVITY | GOMF_NUCLEAR_RECEPTOR_ACTIVITY | GOMF_NUCLEAR_RECEPTOR_ACTIVITY | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | NR5A2/PPARG/THRB/RARB/AHRR/AHR/PGR/ESRRB | 8 |
| HP_ABNORMAL_MUSCLE_FIBER_TYPE_DISTRIBUTION | HP_ABNORMAL_MUSCLE_FIBER_TYPE_DISTRIBUTION | HP_ABNORMAL_MUSCLE_FIBER_TYPE_DISTRIBUTION | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | AGRN/COL6A3/LAMB2/DOK7/TPM2/MYPN/COL13A1/COL6A2 | 8 |
| HP_HYPOVENTILATION | HP_HYPOVENTILATION | HP_HYPOVENTILATION | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | COL6A3/LAMB2/COL12A1/LAMA2/HOXA1/TPM2/MYPN/COL6A2 | 8 |
| WANG_BARRETTS_ESOPHAGUS_UP | WANG_BARRETTS_ESOPHAGUS_UP | WANG_BARRETTS_ESOPHAGUS_UP | 8/1438 | 52/23056 | 0.1538462 | 2.466674 | 2.730787 | 0.0145699 | 0.0496071 | 0.0318907 | FUCA1/GPA33/VIPR1/CLU/AKR1C3/MSLN/ITGA3/ITGB4 | 8 |
| GOBP_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | GOBP_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | GOBP_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 13/1438 | 106/23056 | 0.1226415 | 1.966358 | 2.571899 | 0.0146586 | 0.0498692 | 0.0320592 | S1PR1/RHOC/S100A10/PHLDB2/CCN2/MET/ARHGEF5/NRP1/SYNPO2L/APOA1/CGNL1/TPM1/SDC4 | 13 |
| HP_ABNORMAL_CORNEAL_EPITHELIUM_MORPHOLOGY | HP_ABNORMAL_CORNEAL_EPITHELIUM_MORPHOLOGY | HP_ABNORMAL_CORNEAL_EPITHELIUM_MORPHOLOGY | 13/1438 | 106/23056 | 0.1226415 | 1.966358 | 2.571899 | 0.0146586 | 0.0498692 | 0.0320592 | NLRP3/TWIST2/COL7A1/FGFR3/TGFBI/GSN/FAS/FGFR2/WT1/MMP1/FBN1/COL4A6/COL4A5 | 13 |
| REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | 13/1438 | 106/23056 | 0.1226415 | 1.966358 | 2.571899 | 0.0146586 | 0.0498692 | 0.0320592 | SLC1A7/SLC34A2/SLC4A4/SLC7A11/SLC12A7/SLC26A4/SLC26A7/SLC5A12/SLC15A3/SLC38A4/SLC7A7/SLC24A4/SLC7A10 | 13 |
| GOBP_NEGATIVE_REGULATION_OF_NECROTIC_CELL_DEATH | GOBP_NEGATIVE_REGULATION_OF_NECROTIC_CELL_DEATH | GOBP_NEGATIVE_REGULATION_OF_NECROTIC_CELL_DEATH | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | CASP8/CAV1/BIRC3/YBX3/NUPR1 | 5 |
| GOBP_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | GOBP_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | LBH/HES1/NOTCH1/YAP1/ESRRB | 5 |
| GOBP_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_STRESS | GOBP_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_STRESS | GOBP_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_STRESS | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | NOTCH1/CREB3L1/CREB3L3/KLF2/CEBPB | 5 |
| GOBP_REGULATION_OF_EXCRETION | GOBP_REGULATION_OF_EXCRETION | GOBP_REGULATION_OF_EXCRETION | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | AGT/EDN1/STC1/SPX/EDNRB | 5 |
| GOBP_REGULATION_OF_MACROPHAGE_DIFFERENTIATION | GOBP_REGULATION_OF_MACROPHAGE_DIFFERENTIATION | GOBP_REGULATION_OF_MACROPHAGE_DIFFERENTIATION | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | CSF1/CASP8/INHBA/TGFB1/LIF | 5 |
| GOBP_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | GOBP_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | GOBP_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | TNFRSF1B/IL1B/ADAM9/PTPN3/APOE | 5 |
| GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_RENIN_ANGIOTENSIN | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_RENIN_ANGIOTENSIN | GOBP_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_RENIN_ANGIOTENSIN | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | AGT/SUCNR1/F2RL1/PCSK5/EDNRB | 5 |
| GOBP_RESPONSE_TO_MUSCLE_STRETCH | GOBP_RESPONSE_TO_MUSCLE_STRETCH | GOBP_RESPONSE_TO_MUSCLE_STRETCH | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | EDN1/GSN/ANKRD1/NFKBIA/FOS | 5 |
| GOBP_SKELETAL_MUSCLE_ADAPTATION | GOBP_SKELETAL_MUSCLE_ADAPTATION | GOBP_SKELETAL_MUSCLE_ADAPTATION | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | TRIM63/TNNC1/MYOZ2/IL15/MYOZ1 | 5 |
| GOBP_SULFATION | GOBP_SULFATION | GOBP_SULFATION | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | SULT1C3/SULT1C2/SULT1E1/UST/EXT1 | 5 |
| GOBP_WATER_TRANSPORT | GOBP_WATER_TRANSPORT | GOBP_WATER_TRANSPORT | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | AQP1/HAS2/AQP7/AQP3/SLC14A1 | 5 |
| GOMF_C_C_CHEMOKINE_BINDING | GOMF_C_C_CHEMOKINE_BINDING | GOMF_C_C_CHEMOKINE_BINDING | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | ACKR3/ACKR2/CCR3/CCR7/ZFP36 | 5 |
| GOMF_R_SMAD_BINDING | GOMF_R_SMAD_BINDING | GOMF_R_SMAD_BINDING | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | PPARG/ANKRD1/FOS/SMAD6/MYOCD | 5 |
| HANSON_HRAS_SIGNALING_VIA_NFKB | HANSON_HRAS_SIGNALING_VIA_NFKB | HANSON_HRAS_SIGNALING_VIA_NFKB | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | TSLP/SELPLG/ALDH1A3/SERPINB2/COL18A1 | 5 |
| HP_ABNORMALLY_OSSIFIED_VERTEBRAE | HP_ABNORMALLY_OSSIFIED_VERTEBRAE | HP_ABNORMALLY_OSSIFIED_VERTEBRAE | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | HSPG2/NKX3-2/BMPER/RSPO2/SOX9 | 5 |
| HP_PAROXYSMAL_VENTRICULAR_TACHYCARDIA | HP_PAROXYSMAL_VENTRICULAR_TACHYCARDIA | HP_PAROXYSMAL_VENTRICULAR_TACHYCARDIA | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | SEMA3A/SCNN1A/HCN4/JUP/SCN1B | 5 |
| WANG_LSD1_TARGETS_UP | WANG_LSD1_TARGETS_UP | WANG_LSD1_TARGETS_UP | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | TGFB2/RPRM/PDGFA/SIX1/LGALS1 | 5 |
| WP_EBSTEINBARR_VIRUS_LMP1_SIGNALING | WP_EBSTEINBARR_VIRUS_LMP1_SIGNALING | WP_EBSTEINBARR_VIRUS_LMP1_SIGNALING | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | CXCL8/TRAF1/NFKB2/NFKBIA/CCL5 | 5 |
| ZHAN_MULTIPLE_MYELOMA_SPIKED | ZHAN_MULTIPLE_MYELOMA_SPIKED | ZHAN_MULTIPLE_MYELOMA_SPIKED | 5/1438 | 24/23056 | 0.2083333 | 3.340287 | 2.958443 | 0.0147268 | 0.0498692 | 0.0320592 | CFH/GALNT3/FGFR3/CCN2/EDNRB | 5 |
| HP_RECURRENT_BACTERIAL_INFECTIONS | HP_RECURRENT_BACTERIAL_INFECTIONS | HP_RECURRENT_BACTERIAL_INFECTIONS | 19/1438 | 177/23056 | 0.1073446 | 1.721097 | 2.483798 | 0.0147484 | 0.0499299 | 0.0320982 | GFI1/LAMC2/CFH/LAMB3/CFAP221/CFI/DNAH5/MCIDAS/CCNO/CITED2/SAMD9/MBL2/SCNN1A/SLC7A7/ACTC1/GATA6/ELANE/C3/IL12RB1 | 19 |
5.1.3. Export ADRN and MES tables with all signaling pathways identified
In this part I am exporting the enricher object as a dataframe to an xlsx object where I can specify the excel spreadsheet’s name. I am using a single xlsx object to save the ADRN normoxia and MES normoxia signaling pathways:
5.1.3.1. ADRN Normoxia
library("xlsx")
write.xlsx(as.data.frame(enrichr_RNA_Normoxia_ADRN_vs_MES_Up),
file = "../manuscripts/manuscript versions/Figures/Supplementary Tables/Supplementary_Table-2.xlsx",
sheetName = "ADRN_Normoxia",
append = FALSE)
5.1.3.2. MES Normoxia
library("xlsx")
write.xlsx(as.data.frame(enrichr_RNA_Normoxia_ADRN_vs_MES_Down),
file = "../manuscripts/manuscript versions/Figures/Supplementary Tables/Supplementary_Table-2.xlsx",
sheetName = "MES_Normoxia",
append = TRUE)
It becomes evident now that the parameter append is to append a different excel spreadsheet. In the case above, I first constructed the xlsx object and saved the ADRN normoxia pathways. After, I appended the MES Normoxia signaling values in a different spreadsheet in the same xlsx object.
6. Plots
6.1. ADRN Normoxia
p_adrn_norm <- dotplot(enrichr_RNA_Normoxia_ADRN_vs_MES_Up,
font.size = 6,
showCategory=c(
# The 03 terms below were maintained from Analysis done before
# Abstract Submission on 05/20/2022.
# These terms ended up not changing considering the
# Abstract Submission requests.
# Request changes included LFC and top 10% Up and
# Down-regulated Genes in the Diff. Gene Exp. Analysis.
"GOCC_PRESYNAPSE",
"GOCC_SYNAPTIC_MEMBRANE",
"REACTOME_NEURONAL_SYSTEM",
#"GOCC_MICROTUBULE", This particular term did not hold,
# but th idea should have
"GOMF_TUBULIN_BINDING", # This term held,
# supporting the notion in the line above
"GOBP_NEURON_MIGRATION",# If this involves Microtubule,
# this term supports the notion above
#"GOBP_REGULATION_OF_MICROTUBULE_POLYMERIZATION",
#"GOBP_REGULATION_OF_MICROTUBULE_BASED_PROCESS",
"GOBP_MEMBRANE_DEPOLARIZATION",
"HALLMARK_HYPOXIA",
"HALLMARK_TGF_BETA_SIGNALING"
)) + ggtitle("ADRN Normoxia")+
theme(axis.text.y = element_text(size = 6),
legend.text=element_text(size=6),
legend.key.size = unit(0.2, 'cm'))+
theme_classic()
# Print Graph ADRN Normoxia
p_adrn_norm
6.2. MES Normoxia
p_mes_norm <- dotplot(enrichr_RNA_Normoxia_ADRN_vs_MES_Down,
font.size = 6,
showCategory=c(
"GOCC_COLLAGEN_CONTAINING_EXTRACELLULAR_MATRIX",
"HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION",
"HALLMARK_TNFA_SIGNALING_VIA_NFKB",
"HALLMARK_INFLAMMATORY_RESPONSE",
#"HALLMARK_INTERFERON_ALPHA_RESPONSE",
#"HALLMARK_INTERFERON_GAMMA_RESPONSE",
"HALLMARK_TGF_BETA_SIGNALING",
#"HALLMARK_IL2_STAT5_SIGNALING",
"HALLMARK_HYPOXIA",
#"HALLMARK_GLYCOLYSIS",
#"REACTOME_COLLAGEN_FORMATION",
#"GOMF_COLLAGEN_BINDING",
#"REACTOME_COLLAGEN_CHAIN_TRIMERIZATION",
"REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES"
#"GOMF_COLLAGEN_BINDING"
#"GOBP_COLLAGEN_METABOLIC_PROCESS",
#"REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION",
#"GOMF_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT",
#"REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX"
#"GOMF_EXTRACELLULAR_MATRIX_BINDING"
)
) + ggtitle("MES Normoxia")+
theme(axis.text.y = element_text(size = 6),
legend.text=element_text(size=6),
legend.key.size = unit(0.2, 'cm'))+
theme_classic()
# Print Graph MES Normoxia
p_mes_norm
Session Info
sessionInfo()## R version 4.4.1 (2024-06-14)
## Platform: aarch64-apple-darwin20
## Running under: macOS 15.6
##
## Matrix products: default
## BLAS: /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/libRblas.0.dylib
## LAPACK: /Library/Frameworks/R.framework/Versions/4.4-arm64/Resources/lib/libRlapack.dylib; LAPACK version 3.12.0
##
## locale:
## [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
##
## time zone: America/Chicago
## tzcode source: internal
##
## attached base packages:
## [1] stats graphics grDevices utils datasets methods base
##
## other attached packages:
## [1] xlsx_0.6.5 kableExtra_1.4.0 knitr_1.48
## [4] msigdbr_7.5.1 ggplot2_3.5.1 clusterProfiler_4.12.6
##
## loaded via a namespace (and not attached):
## [1] RColorBrewer_1.1-3 rstudioapi_0.16.0 jsonlite_1.8.9
## [4] magrittr_2.0.3 farver_2.1.2 rmarkdown_2.28
## [7] fs_1.6.4 zlibbioc_1.50.0 vctrs_0.6.5
## [10] memoise_2.0.1 ggtree_3.12.0 htmltools_0.5.8.1
## [13] gridGraphics_0.5-1 sass_0.4.9 bslib_0.8.0
## [16] plyr_1.8.9 httr2_1.0.5 cachem_1.1.0
## [19] igraph_2.0.3 lifecycle_1.0.4 pkgconfig_2.0.3
## [22] Matrix_1.7-0 R6_2.5.1 fastmap_1.2.0
## [25] gson_0.1.0 GenomeInfoDbData_1.2.12 digest_0.6.37
## [28] aplot_0.2.3 enrichplot_1.24.4 colorspace_2.1-1
## [31] patchwork_1.3.0 AnnotationDbi_1.66.0 S4Vectors_0.42.1
## [34] RSQLite_2.3.7 labeling_0.4.3 fansi_1.0.6
## [37] httr_1.4.7 polyclip_1.10-7 compiler_4.4.1
## [40] bit64_4.5.2 withr_3.0.1 BiocParallel_1.38.0
## [43] viridis_0.6.5 DBI_1.2.3 highr_0.11
## [46] ggforce_0.4.2 R.utils_2.12.3 MASS_7.3-61
## [49] rappdirs_0.3.3 tools_4.4.1 ape_5.8
## [52] scatterpie_0.2.4 R.oo_1.26.0 glue_1.8.0
## [55] nlme_3.1-166 GOSemSim_2.30.2 grid_4.4.1
## [58] shadowtext_0.1.4 reshape2_1.4.4 fgsea_1.30.0
## [61] generics_0.1.3 gtable_0.3.5 R.methodsS3_1.8.2
## [64] tidyr_1.3.1 data.table_1.16.0 tidygraph_1.3.1
## [67] xml2_1.3.6 utf8_1.2.4 XVector_0.44.0
## [70] BiocGenerics_0.50.0 ggrepel_0.9.6 pillar_1.9.0
## [73] stringr_1.5.1 yulab.utils_0.1.7 babelgene_22.9
## [76] rJava_1.0-11 splines_4.4.1 dplyr_1.1.4
## [79] tweenr_2.0.3 treeio_1.28.0 lattice_0.22-6
## [82] bit_4.5.0 tidyselect_1.2.1 GO.db_3.19.1
## [85] Biostrings_2.72.1 gridExtra_2.3 IRanges_2.38.1
## [88] svglite_2.1.3 stats4_4.4.1 xfun_0.48
## [91] graphlayouts_1.2.0 Biobase_2.64.0 stringi_1.8.4
## [94] UCSC.utils_1.0.0 lazyeval_0.2.2 ggfun_0.1.6
## [97] yaml_2.3.10 xlsxjars_0.9.0 evaluate_1.0.0
## [100] codetools_0.2-20 ggraph_2.2.1 tibble_3.2.1
## [103] qvalue_2.36.0 ggplotify_0.1.2 cli_3.6.3
## [106] systemfonts_1.1.0 munsell_0.5.1 jquerylib_0.1.4
## [109] Rcpp_1.0.13 GenomeInfoDb_1.40.1 png_0.1-8
## [112] parallel_4.4.1 blob_1.2.4 DOSE_3.30.5
## [115] viridisLite_0.4.2 tidytree_0.4.6 scales_1.3.0
## [118] purrr_1.0.2 crayon_1.5.3 rlang_1.1.4
## [121] cowplot_1.1.3 fastmatch_1.1-4 KEGGREST_1.44.1